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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

6-Chlorooxindole Manufacturer/High quality/Best price/In stock

Cas:56341-37-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 6-Chlorooxindole supplier in China

Cas:56341-37-8

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

High quality 6-Chlorooxindole CAS 56341-37-8 with factory price Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed addit

High quality 6-Chlorooxindole CAS 56341-37-8 with factory price

Cas:56341-37-8

Min.Order:10 Kilogram

FOB Price: $10.0

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

Good quality Good price Promptly delivery Appearance:white powder Storage:dry dondition Package:According to the demand of customer Application:intermediate Transportation:According to the demand of customer Port:shanghai

6-Chlorooxindole56341-37-8

Cas:56341-37-8

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 6-chloro-1,3-dihydroindol-2-one

Cas:56341-37-8

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% 56341-37-8 6-Chloro-1,3-dihydro-indol-2-one Manufacturer

Cas:56341-37-8

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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ANQING CHICO PHARMACEUTICAL CO.,LTD.

High quality. Factory supply. In stock. Best price.1.Quick response within 24 hours;2.Best quality in your requirement;?3.We pay more attention on delivery time, and usually ship on time;4.Under the premise of safety and effectiveness, we can produce

6-Chlorooxindole

Cas:56341-37-8

Min.Order:0

Negotiable

Type:Trading Company

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

6-Chlorooxindole

Cas:56341-37-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Product Name: 6-Chlorooxindole Synonyms: 6-Chloro-2-oxindole in stock Factory;6-Chloro-1,3-dihydroindole-2-one;6-Chlorooxindole,98%;6-Chloro-1,3-dihvdro-indol-2-one;6-Chloro-2-oxindole 98%;6-chloro indole ketone;6-Chloroindolin-2-one, 6-Chloro-1,3

6-Chlorooxindole 56341-37-8

Cas:56341-37-8

Min.Order:1 Kilogram

FOB Price: $230.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

6-Chlorooxindole

Cas:56341-37-8

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 56341-37-8 with fast shipping

Cas:56341-37-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product Name 6-Chlorooxindole Synonyms 6-Chlorooxindole;H-indol-6-yl hypochlorite CAS: 56341-37-8 MF: - MW: - EINECS:

6-Chlorooxindole CAS: 56341-37-8

Cas:56341-37-8

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:white or off-white powder Storage:Store in sealed containers

Intermediate 6-Chlorooxindole 56341-37-8

Cas:56341-37-8

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2H-Indol-2-one,6-chloro-1,3-dihydro- 56341-37-8

Cas:56341-37-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the

2H-Indol-2-one,6-chloro-1,3-dihydro-/ LIDE PHARMA- Factory supply / Best price

Cas:56341-37-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

6-Chlorooxindole CAS:56341-37-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermed

6-Chlorooxindole CAS:56341-37-8

Cas:56341-37-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2H-Indol-2-one,6-chloro-1,3-dihydro-

Cas:56341-37-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Sankai Chemical Technology Co., Ltd

Hebei Sankai Chemical Technology Co., LTD. is located in xingtai City, Hebei Province, China. It is a biotechnology enterprise engaged in the research, development, production and sales of animal and plant extracts, cosmetics, pharmaceutical raw mate

Buy High Quality 56341-37-8 56341-37-8 USP 56341-37-8 In Medicine

Cas:56341-37-8

Min.Order:1 Kilogram

FOB Price: $2.5 / 5.0

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2H-Indol-2-one,6-chloro-1,3-dihydro-

Cas:56341-37-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

6-Chlorooxindole

Cas:56341-37-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Service 1.Own made fine chemical products 2.Out sourcing and quality c

6-Chloro-1,3-dihydro-indol-2-one

Cas:56341-37-8

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

6-Chlorooxindole 56341-37-8

Cas:56341-37-8

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

6-CHLOROOXINDOLE

Cas:56341-37-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

6-Chlorooxindole

Cas:56341-37-8

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

6-Chlorooxindole

Cas:56341-37-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

6-chloro-2-oxindole

Cas:56341-37-8

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

our strengths: 1: Fast and guaranteed shipment (TNT;EMS;FEDEX;DHL;UPS;EUB, special line) 2: Various payment items accepted (Btc; MoneyGram; WU) 3: Valued package (Paraffin coating; Double aluminum foil bag; Vacuum packaging) 4: Efficient delivery

Best price/In stock 6-Chlorooxindole 56341-37-8

Cas:56341-37-8

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products 6-Chlorooxindole

Cas:56341-37-8

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Send Pharmaceutical Technology Co., Ltd.

low price high quality high purity good sevice stock Appearance:white Storage:Preserve In Well-Closed, Light-Resistant and Tight Containers. Store In Cool & Dry Place Package:1g,5g,10g...1kg,5kg...more Application:Pharmaceutical intermediat

6-Chlorooxindole

Cas:56341-37-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 6-Chlorooxindole

Cas:56341-37-8

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Synthetic route

6-chloroisatin
6341-92-0

6-chloroisatin

6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

Conditions
ConditionsYield
With titanium tetrachloride; zinc In tetrahydrofuran at 20℃; for 0.0833333h; Inert atmosphere;88%
Multi-step reaction with 2 steps
1: hydrazine hydrate / ethanol / 0.5 h / Heating
2: Na / ethanol / Heating
View Scheme
With sodium ethanolate; hydrazine hydrate In ethanol
methyl 2-(4-chloro-2-nitrophenyl)acetate
147124-37-6

methyl 2-(4-chloro-2-nitrophenyl)acetate

6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

Conditions
ConditionsYield
With iron In acetic acid at 100℃; for 1h;87%
Multi-step reaction with 2 steps
1: palladium 10% on activated carbon; hydrogen / ethyl acetate / 20 °C / 2280.15 Torr / Sealed tube
2: ethyl acetate / 6 h / Reflux; Molecular sieve
View Scheme
(4-Chlor-2-nitro-phenyl)-malonsaeure-diaethylester
10565-16-9

(4-Chlor-2-nitro-phenyl)-malonsaeure-diaethylester

6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

Conditions
ConditionsYield
With hydrogenchloride; tin In ethanol Heating;79%
dimethyl (4-chloro-2-nitrophenyl)malonate
147124-32-1

dimethyl (4-chloro-2-nitrophenyl)malonate

6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

Conditions
ConditionsYield
With iron; acetic acid In 5,5-dimethyl-1,3-cyclohexadiene at 25 - 105℃; Large scale;75%
Stage #1: dimethyl (4-chloro-2-nitrophenyl)malonate With hydrogenchloride; water In methanol at 20 - 95℃; Large scale;
Stage #2: With tin In methanol at 45 - 95℃; Large scale;
75%
Stage #1: dimethyl (4-chloro-2-nitrophenyl)malonate With lithium chloride In dimethyl sulfoxide at 100℃; for 3h;
Stage #2: With iron; acetic acid at 100℃; for 1h;
dimethyl 4-chloro-2-nitrophenyl malonate

dimethyl 4-chloro-2-nitrophenyl malonate

6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

Conditions
ConditionsYield
With hydrogen; acetic acid; Pt/C In water71%
4-chloro-2-nitro-phenylacetic acid
37777-71-2

4-chloro-2-nitro-phenylacetic acid

A

6-chloro-1-hydroxy-indolin-2-one
28230-26-4

6-chloro-1-hydroxy-indolin-2-one

B

6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

Conditions
ConditionsYield
Stage #1: 4-chloro-2-nitro-phenylacetic acid With 1,10-Phenanthroline; platinum on carbon; hydrogen In ethanol at 20℃; under 7500.75 Torr; Flow reactor; Green chemistry;
Stage #2: With acetic acid In ethanol at 20℃; Green chemistry;
A 63%
B n/a
3-Chloroacetanilide
588-07-8

3-Chloroacetanilide

ethyl iodoacetae
623-48-3

ethyl iodoacetae

6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

Conditions
ConditionsYield
With silver(I) acetate; palladium diacetate; trifluoroacetic acid at 120℃; for 24h; Sealed tube; Inert atmosphere; Schlenk technique; regioselective reaction;53%
2-chloro-N-(3-chlorophenyl)acetamide
2564-05-8

2-chloro-N-(3-chlorophenyl)acetamide

A

4-chloroindolin-2-one
20870-77-3

4-chloroindolin-2-one

B

6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

Conditions
ConditionsYield
With aluminium trichloride 1. 50-60 deg C, 10 min; 2. 150-160 deg C, 2 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With aluminium trichloride Product distribution; 50-60 deg C, 10 min; 150-160 deg C, 2 h;
6-chloroisatin 3-hydrazone
879-32-3

6-chloroisatin 3-hydrazone

6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

Conditions
ConditionsYield
With sodium In ethanol Heating; Yield given;
With potassium tert-butylate In ethanol for 2h; Reflux; Inert atmosphere;
2,5-dichloronitrobenzene
89-61-2

2,5-dichloronitrobenzene

6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: tBuOK / dimethylformamide / 0.17 h / 90 °C
1.2: dimethylformamide / 2 h / 90 °C
2.1: LiCl / dimethylsulfoxide / 3 h / 100 °C
2.2: acetic acid; iron / 1 h / 100 °C
View Scheme
Multi-step reaction with 2 steps
1: 84 percent / NaH / dimethylsulfoxide / 100 °C
2: 79 percent / Sn, HCl / ethanol / Heating
View Scheme
Multi-step reaction with 3 steps
1: 1) NaH / 1) DMSO, 100 deg C, 40 min, 2a) RT, 30 min, 2b) 100 deg C, 1 h
2: 69 percent / LiCl / dimethylsulfoxide; H2O / 3 h / 100 °C
3: 87 percent / Fe powder / acetic acid / 1 h / 100 °C
View Scheme
3-chloro-aniline
108-42-9

3-chloro-aniline

6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 62 percent / benzene / Heating
2: AlCl3 / 50-60 deg C, 10 min; 150-160 deg C, 2 h
View Scheme
Multi-step reaction with 4 steps
1.1: hydrogenchloride; hydroxylamine hydrochloride; sodium sulfate / water / 60 - 70 °C
2.1: sulfuric acid / 80 - 90 °C
3.1: sulfuric acid; water
4.1: hydrazine hydrate / ethanol / Reflux
4.2: Reflux
View Scheme
Multi-step reaction with 4 steps
1: sodium sulfate; sulfuric acid; hydroxylamine hydrochloride / water / 0.5 h / 130 °C
2: sulfuric acid / 1 h / 50 - 70 °C
3: hydrazine hydrate / ethanol / 0.5 h / Inert atmosphere; Reflux
4: potassium tert-butylate / ethanol / 2 h / Reflux; Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: dichloromethane / 20 °C / Inert atmosphere
2: palladium diacetate; silver(I) acetate; trifluoroacetic acid / 24 h / 120 °C / Sealed tube; Inert atmosphere; Schlenk technique
View Scheme
4-chloro-2-nitro-phenylacetic acid
37777-71-2

4-chloro-2-nitro-phenylacetic acid

6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

Conditions
ConditionsYield
Stage #1: 4-chloro-2-nitro-phenylacetic acid With iron; acetic acid In methanol at 50 - 75℃; for 1h;
Stage #2: With hydrogenchloride In methanol; water at 20 - 25℃;
Multi-step reaction with 2 steps
1: sodium dithionite / ethanol / 4 h / 40 - 45 °C
2: hydrogenchloride / ethanol / 2 h / 70 - 75 °C / pH 2 - 2.5
View Scheme
6-chloro-3-iminoindolin-2-one
1261152-95-7

6-chloro-3-iminoindolin-2-one

6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sulfuric acid; water
2.1: hydrazine hydrate / ethanol / Reflux
2.2: Reflux
View Scheme
Ν-(3-chlorophenyl)-2-hydroxyiminoacetamide
17122-55-3

Ν-(3-chlorophenyl)-2-hydroxyiminoacetamide

6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: sulfuric acid / 80 - 90 °C
2.1: sulfuric acid; water
3.1: hydrazine hydrate / ethanol / Reflux
3.2: Reflux
View Scheme
Multi-step reaction with 3 steps
1: sulfuric acid / 1 h / 50 - 70 °C
2: hydrazine hydrate / ethanol / 0.5 h / Inert atmosphere; Reflux
3: potassium tert-butylate / ethanol / 2 h / Reflux; Inert atmosphere
View Scheme
2-nitro-4-chlorobenzene diazonium tetrafluoroborate

2-nitro-4-chlorobenzene diazonium tetrafluoroborate

6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: tris(bipyridine)ruthenium(II) dichloride hexahydrate; oxygen / 20 °C / Irradiation
2: palladium 10% on activated carbon; hydrogen / ethyl acetate / 20 °C / 2280.15 Torr / Sealed tube
3: ethyl acetate / 6 h / Reflux; Molecular sieve
View Scheme
methyl 2-(2-amino-4-chlorophenyl)acetate

methyl 2-(2-amino-4-chlorophenyl)acetate

6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

Conditions
ConditionsYield
In ethyl acetate for 6h; Reflux; Molecular sieve;
(2-amino-4-chlorophenyl)acetic acid
177985-31-8

(2-amino-4-chlorophenyl)acetic acid

6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

Conditions
ConditionsYield
With hydrogenchloride In ethanol at 70 - 75℃; for 2h; pH=2 - 2.5;
2-(4-chloro-2-nitrophenyl)malonate potassium

2-(4-chloro-2-nitrophenyl)malonate potassium

6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: hydrogenchloride / ethanol / 1 h / 0 - 40 °C / pH 6 - 6.5
2: sodium dithionite / ethanol / 4 h / 40 - 45 °C
3: hydrogenchloride / ethanol / 2 h / 70 - 75 °C / pH 2 - 2.5
View Scheme
2-(4-chloro-2-nitrophenyl)malonate sodium

2-(4-chloro-2-nitrophenyl)malonate sodium

6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: hydrogenchloride / ethanol / 1 h / 0 - 40 °C / pH 6 - 6.5
2: sodium dithionite / ethanol / 4 h / 40 - 45 °C
3: hydrogenchloride / ethanol / 2 h / 70 - 75 °C / pH 2 - 2.5
View Scheme
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

3,3-Dibromo-6-chloro-1,3-dihydro-indol-2-one
215959-30-1

3,3-Dibromo-6-chloro-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
With pyridinium hydrobromide perbromide In water; tert-butyl alcohol at 20℃; for 3.5h;100%
With pyridinium perbromide hydrobromide In water; tert-butyl alcohol for 16h;99%
With copper(ll) bromide In ethyl acetate at 80℃;
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

Me2NCH(OR)2

Me2NCH(OR)2

6-Chloro-3-[1-dimethylamino-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one

6-Chloro-3-[1-dimethylamino-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
In chloroform Heating;100%
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

methyl 2-oxobutanoate
3952-66-7

methyl 2-oxobutanoate

C13H14ClNO4

C13H14ClNO4

Conditions
ConditionsYield
With piperidine In methanol at 0 - 20℃; for 24h;97%
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

2-fluoro-3-chlorobenzaldehyde
85070-48-0

2-fluoro-3-chlorobenzaldehyde

6-chloro-3-[1-(3-chloro-2-fluorophenyl)-meth-(E)-ylidene]-1,3-dihydroindol-2-one
908027-64-5

6-chloro-3-[1-(3-chloro-2-fluorophenyl)-meth-(E)-ylidene]-1,3-dihydroindol-2-one

Conditions
ConditionsYield
With piperidine In methanol at 20℃; Reflux;96%
With piperidine for 6h; Reflux;95%
With piperidine for 6h; Reflux;95%
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

salicylaldehyde
90-02-8

salicylaldehyde

C15H8ClNO

C15H8ClNO

Conditions
ConditionsYield
With H4[PVMo11O40] suppoted montmorillonite K-10 clay In neat (no solvent) at 100℃; for 1h; Green chemistry;96%
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

5-bromo-6-chloro-1,3-dihydro-2H-indol-2-one

5-bromo-6-chloro-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
With N-Bromosuccinimide In acetonitrile at -10 - 20℃; for 3h;95.8%
With N-Bromosuccinimide In acetonitrile at -10 - 20℃; for 3h;95.8%
With N-Bromosuccinimide In acetonitrile at -10 - 20℃; for 5h;4.5 g
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

3-Chlorobenzaldehyde
587-04-2

3-Chlorobenzaldehyde

E/Z-6-chloro-3-[1-(3-chlorophenyl)methylidene]-1,3-dihydroindol-2-one
387344-30-1

E/Z-6-chloro-3-[1-(3-chlorophenyl)methylidene]-1,3-dihydroindol-2-one

Conditions
ConditionsYield
With pyrrolidine In methanol at 70℃; for 3h;95%
With pyrrolidine In methanol at 70℃; for 3h;95%
With pyrrolidine In methanol at 70℃; for 3h;95%
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

acetone
67-64-1

acetone

6-chloro-3-(propan-2-ylidene)indolin-2-one
1374606-24-2

6-chloro-3-(propan-2-ylidene)indolin-2-one

Conditions
ConditionsYield
With morpholine for 16h; Knoevenagel Condensation; Reflux;95%
With piperidine In ethanol at 23℃; for 4h;
With piperidine at 120℃; for 0.166667h; Microwave irradiation; Inert atmosphere;
With piperidine In ethanol at 23℃; for 4h; Inert atmosphere;
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

diphenyl(vinyl)sulfonium trifluoromethanesulfonate

diphenyl(vinyl)sulfonium trifluoromethanesulfonate

6'-chloro-1',2'-dihydrospiro[cyclopropane-1,3'-indole]-2'-one

6'-chloro-1',2'-dihydrospiro[cyclopropane-1,3'-indole]-2'-one

Conditions
ConditionsYield
With zinc trifluoromethanesulfonate; 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 21℃; for 4h;95%
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

2-fluoro-3-chlorobenzaldehyde
85070-48-0

2-fluoro-3-chlorobenzaldehyde

(3E/Z)-6-chloro-3-(3-chloro-2-fluorobenzylidene)-1,3-dihydro-2H-indol-2-one
897365-76-3

(3E/Z)-6-chloro-3-(3-chloro-2-fluorobenzylidene)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
With piperidine In ethanol at 80℃; for 2h; Inert atmosphere;94%
With piperidine In methanol at 50℃; for 3h;89%
With piperidine In ethanol for 8h; Inert atmosphere; Reflux;
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

acetic anhydride
108-24-7

acetic anhydride

1,3-diacetyl-6-chloro-1H-indol-2-yl acetate
1195737-73-5

1,3-diacetyl-6-chloro-1H-indol-2-yl acetate

Conditions
ConditionsYield
With dmap at 150℃; for 1h;93%
With dmap at 150℃; for 1h;93%
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

phenyl chloroformate
1885-14-9

phenyl chloroformate

6-chloro-2-phenoxycarbonyloxy-indole-1-carboxylic acid phenyl ester
301700-14-1

6-chloro-2-phenoxycarbonyloxy-indole-1-carboxylic acid phenyl ester

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 20℃; for 0.5h; Acylation;92%
With triethylamine In tetrahydrofuran
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

6-chloroindoline-2-thione
392332-34-2

6-chloroindoline-2-thione

Conditions
ConditionsYield
With tetraphosphorus decasulfide; sodium hydrogencarbonate In tetrahydrofuran at 20℃; for 4h;92%
Stage #1: 6-chloro-2-oxindole With sodium hydrogencarbonate In tetrahydrofuran at 20℃; for 0.166667h;
Stage #2: With tetraphosphorus decasulfide In tetrahydrofuran at 20℃;
Stage #1: 6-chloro-2-oxindole With sodium hydrogencarbonate In tetrahydrofuran at 20℃; for 0.166667h;
Stage #2: With tetraphosphorus decasulfide In tetrahydrofuran at 20℃;
With Lawessons reagent In tetrahydrofuran for 24h; Reflux;
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

2-chloropropionyl chloride
625-36-5

2-chloropropionyl chloride

6-chloro-5-(3-chloro-propionyl)-1,3-dihydro-indol-2-one
860024-14-2

6-chloro-5-(3-chloro-propionyl)-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
With aluminum (III) chloride In carbon disulfide at 20℃; for 3h; Heating / reflux;92%
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

6-chloro-2-oxindole-3-thione S-oxide
1261171-12-3

6-chloro-2-oxindole-3-thione S-oxide

Conditions
ConditionsYield
With thionyl chloride In acetonitrile at 25 - 30℃; for 0.166667h;92%
3-bromo-2-fluorobenzaldehyde
149947-15-9

3-bromo-2-fluorobenzaldehyde

6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

(E/Z)-3-(3-bromo-2-fluoro-benzylidene)-6-chloro-1,3-dihydro-indol-2-one
1309685-47-9

(E/Z)-3-(3-bromo-2-fluoro-benzylidene)-6-chloro-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
With piperidine In methanol at 80℃; for 2h;92%
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

3-chloro-5-fluorobenzaldehyde
90390-49-1

3-chloro-5-fluorobenzaldehyde

(3E/Z)-6-chloro-3-(3-chloro-5-fluorobenzylidene)-1,3-dihydro-2H-indol-2-one
1309685-27-5

(3E/Z)-6-chloro-3-(3-chloro-5-fluorobenzylidene)-1,3-dihydro-2H-indol-2-one

Conditions
ConditionsYield
With piperidine In methanol at 80℃; for 2h;92%
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

chloroacetyl chloride
79-04-9

chloroacetyl chloride

6-chloro-5-(2-chloroacetyl) indolin-2-one
118307-04-3

6-chloro-5-(2-chloroacetyl) indolin-2-one

Conditions
ConditionsYield
With aluminum (III) chloride In dichloromethane at 0 - 30℃; for 24h; Inert atmosphere;90.6%
With aluminium trichloride In carbon disulfide
With aluminum (III) chloride In dichloromethane at 0 - 45℃; for 14h; Heating / reflux;
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

4-(4-bromo-2-formyl-phenoxy)-piperidine-1-carboxylic acid tert-butyl ester
1160653-87-1

4-(4-bromo-2-formyl-phenoxy)-piperidine-1-carboxylic acid tert-butyl ester

E/Z-4-[4-bromo-2-(6-chloro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-phenoxy]-piperidine-1-carboxylic acid tert-butyl ester
1162669-96-6

E/Z-4-[4-bromo-2-(6-chloro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-phenoxy]-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With piperidine In methanol at 100℃; for 3h;90%
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

p-Chlorothiophenol
106-54-7

p-Chlorothiophenol

6-chloro-3-((4-chlorophenyl)thio)indolin-2-one

6-chloro-3-((4-chlorophenyl)thio)indolin-2-one

Conditions
ConditionsYield
With iron(III) chloride; potassium carbonate In dimethyl sulfoxide at 50℃; for 1.5h; Green chemistry;90%
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

malononitrile
109-77-3

malononitrile

2-(6-chloro-2-oxoindolin-3-ylidene)malononitrile
1356828-86-8

2-(6-chloro-2-oxoindolin-3-ylidene)malononitrile

Conditions
ConditionsYield
With iron(III) chloride hexahydrate; oxygen In N,N-dimethyl-formamide at 50℃; for 5h; Green chemistry;90%
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

6-chloroisatin
6341-92-0

6-chloroisatin

Conditions
ConditionsYield
With oxygen; copper(II) acetate monohydrate; potassium carbonate In N,N-dimethyl-formamide at 50℃; under 760.051 Torr; for 0.5h;89%
Stage #1: 6-chloro-2-oxindole With pyridinium perbromide hydrobromide
Stage #2: With methanol; water
85%
Multi-step reaction with 2 steps
1: CuBr2 / ethyl acetate / 80 °C
2: water / methanol / 2 h / Heating
View Scheme
Multi-step reaction with 2 steps
1: 99 percent / pyridine*HBr*Br2 / 2-methyl-propan-2-ol; H2O / 16 h
2: 57 percent / H2O / methanol / 50 h / Heating
View Scheme
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

azulene
275-51-4

azulene

1-(6-chloroindol-2-yl)azulene
1365097-46-6

1-(6-chloroindol-2-yl)azulene

Conditions
ConditionsYield
Stage #1: 6-chloro-2-oxindole; azulene With trifluoromethylsulfonic anhydride In dichloromethane at 20℃; for 2.5h; Vilsmeier-Haack type arylation;
Stage #2: With potassium carbonate In dichloromethane; water
89%
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

4-methyl-benzaldehyde
104-87-0

4-methyl-benzaldehyde

(E)-3-(4-methylbenzylidene)-6-chloroindolin-2-one
1612883-15-4

(E)-3-(4-methylbenzylidene)-6-chloroindolin-2-one

Conditions
ConditionsYield
With piperidine In ethanol for 3h; Reflux;89%
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

(3-oxo-butyl)-propyl-carbamic acid tert-butyl ester

(3-oxo-butyl)-propyl-carbamic acid tert-butyl ester

4-(6-chloro-2-oxo-1,2-dihydro-indol-3-ylidene)-azepane-1-carboxylic acid tert-butyl ester

4-(6-chloro-2-oxo-1,2-dihydro-indol-3-ylidene)-azepane-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With pyrrolidine In isopropyl alcohol at 90℃; for 48h;88%
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

4-(Methylthio)benzaldehyde
3446-89-7

4-(Methylthio)benzaldehyde

(E)-3-(4-(methylthio)benzylidene)-6-chloroindolin-2-one
1612883-12-1

(E)-3-(4-(methylthio)benzylidene)-6-chloroindolin-2-one

Conditions
ConditionsYield
With piperidine In ethanol for 3h; Reflux;88%
piperidine
110-89-4

piperidine

1H-indol-2-ylcarboxaldehyde
19005-93-7

1H-indol-2-ylcarboxaldehyde

6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

6-chloro-3-(1H-indol-2-ylmethylene)-1,3-dihydro-indol-2-one

6-chloro-3-(1H-indol-2-ylmethylene)-1,3-dihydro-indol-2-one

Conditions
ConditionsYield
In ethanol87%
6-chloro-2-oxindole
56341-37-8

6-chloro-2-oxindole

acetic anhydride
108-24-7

acetic anhydride

1-acetyl-6-chloroindolin-2-one
651747-72-7

1-acetyl-6-chloroindolin-2-one

Conditions
ConditionsYield
at 130℃; for 7h;87%
With sodium carbonate In tetrahydrofuran at 20℃; for 12h; Inert atmosphere;

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