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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

3,4-Dichloro-1,2,5-thiadiazole

Cas:5728-20-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Jinan Finer Chemical Co., Ltd

Product informations Product Name 3,4-Dichloro-1,2,5-thiadiazole CAS No. 5728-20-1

3,4-Dichloro-1,2,5-thiadiazole

Cas:5728-20-1

Min.Order:1 Gram

FOB Price: $8.0

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 3,4-dichloro-1,2,5-thiadiazole

Cas:5728-20-1

Min.Order:1

Negotiable

Type:Other

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Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality 3,4-Dichloro-1,2,5-thiadiazole

Cas:5728-20-1

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3,4-Dichloro-1,2,5-thiadiazole

Cas:5728-20-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

chengdu and import and export trade co., LTD., who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do res

3,4-Dichloro-1,2,5-thiadiazole 5728-20-1 in stock

Cas:5728-20-1

Min.Order:1 Kilogram

FOB Price: $400.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 5728-20-1 with best quality

Cas:5728-20-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

3,4-Dichloro-1,2,5-thiadiazole

Cas:5728-20-1

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

3,4-Dichloro-1,2,5-thiadiazole 5728-20-1

Cas:5728-20-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

3,4-Dichloro-1,2,5-thiadiazole

Cas:5728-20-1

Min.Order:1 Kilogram

FOB Price: $200.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

3,4-Dichloro-1,2,5-thiadiazole CAS:5728-20-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality org

3,4-Dichloro-1,2,5-thiadiazole CAS:5728-20-1

Cas:5728-20-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

3,4-Dichloro-1,2,5-thiadiazole

Cas:5728-20-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

3,4-Dichloro-1,2,5-thiadiazole

Cas:5728-20-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

3,4-Dichloro-1,2,5-thiadiazole

Cas:5728-20-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

3,4-Dichloro-1,2,5-thiadiazole

Cas:5728-20-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hefei Zhaobo Technology Co., Ltd.

3,4-Dichloro-1,2,5-thiadiazole cas 5728-20-1 Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict qu

3,4-Dichloro-1,2,5-thiadiazole cas 5728-20-1

Cas:5728-20-1

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Hebei Miheng Trading Co., Ltd.

Dipeptide diaminobutyroyl benzylamide diacetate CAS 823202-99-9 Our advantage 1.Top quality: Using high quality material and establishing a strict quality control system,assigning specific persons in charge of each part of production,from raw

3,4-Dichloro-1,2,5-thiadiazole CAS 5728-20-1

Cas:5728-20-1

Min.Order:1 Kilogram

FOB Price: $50.0 / 100.0

Type:Trading Company

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

3,4-Dichloro-1,2,5-thiadiazole

Cas:5728-20-1

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3,4-Dichloro-1,2,5-thiadiazole

Cas:5728-20-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High purity 3,4-Dichloro-1,2,5-thiadiazole

Cas:5728-20-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

3,4-Dichloro-1,2,5-thiadiazole

Cas:5728-20-1

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

3,4-Dichloro-1,2,5-thiadiazole

Cas:5728-20-1

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

3,4-Dichloro-1,2,5-thiadiazole,5728-20-1

Cas:5728-20-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

3,4-Dichloro-1,2,5-thiadiazole

Cas:5728-20-1

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

3,4-Dichloro-1,2,5-thiadiazole,5728-20-1

Cas:5728-20-1

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

3,4-Dichloro-1,2,5-thiadiazole

Cas:5728-20-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

3,4-Dichloro-1,2,5-thiadiazole,5728-20-1

Cas:5728-20-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

3,4-Dichloro-1,2,5-thiadiazole,5728-20-1

Cas:5728-20-1

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:Colorless or light yellow liquid Storage:stored in a cool, dry and ventilated place to provent sun and rain Package:25kg/drum, or as per your request. Application:Used as Pharmac

3,4-Dichloro-1,2,5-thiadiazole

Cas:5728-20-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Cas no.5728-20-1 98% 3,4-Dichloro-1,2,5-thiadiazole

Cas:5728-20-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

dichloroglyoxime
2038-44-0

dichloroglyoxime

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

Conditions
ConditionsYield
With pyridine; disulfur dichloride In acetonitrile at -25℃; for 5h; Inert atmosphere; Reflux;78%
With sulfur dichloride In N,N-dimethyl-formamide
ethanedinitrile
460-19-5

ethanedinitrile

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

Conditions
ConditionsYield
With disulfur dichloride In N,N-dimethyl-formamide
With sulfur dichloride
hexa-P-phenyl-P,P'-ethane-1,2-diyldiamino-bis-phosphonium; dichloride
33355-75-8

hexa-P-phenyl-P,P'-ethane-1,2-diyldiamino-bis-phosphonium; dichloride

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

Conditions
ConditionsYield
With sulfur tetrafluoride; triethylamine In dichloromethane
2-aminoacetonitrile
540-61-4

2-aminoacetonitrile

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

Conditions
ConditionsYield
With disulfur dichloride; chlorine In N,N-dimethyl-formamide
1,2-diaminoethane dihydrochloride
333-18-6

1,2-diaminoethane dihydrochloride

A

3-Chloro-1,2,5-thiadiazole
5097-45-0

3-Chloro-1,2,5-thiadiazole

B

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

Conditions
ConditionsYield
With disulfur dichloride; chlorine; iron In N,N-dimethyl-formamideA 5 g
B 115.7 g
piperidine
110-89-4

piperidine

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

3-(piperidin-1-yl)-4-chloro-1,2,5-thiadiazole

3-(piperidin-1-yl)-4-chloro-1,2,5-thiadiazole

Conditions
ConditionsYield
at 110 - 120℃;100%
at 90 - 100℃; Inert atmosphere;94%
In neat (no solvent) at 90℃; for 2h;
In neat (no solvent) at 90℃; for 2h;
4-benzylpyperidine
31252-42-3

4-benzylpyperidine

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

3-(4-benzylpiperidin-1-yl)-4-chloro-1,2,5-thiadiazole

3-(4-benzylpiperidin-1-yl)-4-chloro-1,2,5-thiadiazole

Conditions
ConditionsYield
at 110 - 120℃;100%
morpholine
110-91-8

morpholine

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

3-Morpholino-4-chloro-1,2,5-thiadiazole
30165-96-9

3-Morpholino-4-chloro-1,2,5-thiadiazole

Conditions
ConditionsYield
98%
at 110℃; for 2.5h; Inert atmosphere;95%
at 110 - 120℃;90%
hexamethylene imine
111-49-9

hexamethylene imine

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

3-(1-azepanyl)-4-chloro-1,2,5-thiadiazole
1119451-34-1

3-(1-azepanyl)-4-chloro-1,2,5-thiadiazole

Conditions
ConditionsYield
at 120℃; for 4h; Inert atmosphere;98%
(S)-1-tert-butylamino-2,3-dihydroxypropane
30315-46-9

(S)-1-tert-butylamino-2,3-dihydroxypropane

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

(S)-(-)-3-(3-tert-butylamnio-2-hydroxypropoxy)-4-chloro-1,2,5-thiadiazole
26791-15-1

(S)-(-)-3-(3-tert-butylamnio-2-hydroxypropoxy)-4-chloro-1,2,5-thiadiazole

Conditions
ConditionsYield
With potassium tert-butylate In tert-butyl alcohol for 1h; Heating / reflux;96.6%
3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

4,5-dimethyl-2-(trimethylsilyl)phenyl triflate

4,5-dimethyl-2-(trimethylsilyl)phenyl triflate

3-chloro-5,6-dimethyl-1,2-benzoisothiazole
41533-37-3

3-chloro-5,6-dimethyl-1,2-benzoisothiazole

Conditions
ConditionsYield
With cesium fluoride In tetrahydrofuran Inert atmosphere;96%
3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

6-(trimethylsilyl)benzo[d][1,3]dioxol-5-yl triflate
717903-52-1

6-(trimethylsilyl)benzo[d][1,3]dioxol-5-yl triflate

3-chloro-5,6-dioxolo-1,2-benzoisothiazole

3-chloro-5,6-dioxolo-1,2-benzoisothiazole

Conditions
ConditionsYield
With cesium fluoride In tetrahydrofuran Inert atmosphere;96%
3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

4,5-dimethoxy-2-(trimethylsilyl)phenyl trifluoromethanesulfonate

4,5-dimethoxy-2-(trimethylsilyl)phenyl trifluoromethanesulfonate

3-chloro-5,6-dimethoxy-1,2-benzoisothiazole

3-chloro-5,6-dimethoxy-1,2-benzoisothiazole

Conditions
ConditionsYield
With cesium fluoride In tetrahydrofuran Inert atmosphere;93%
3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

A

2-(Chlorimino)-N-(difluor-λ4-sulfanyliden)-1,1,2-trifluorethanamin
82878-41-9

2-(Chlorimino)-N-(difluor-λ4-sulfanyliden)-1,1,2-trifluorethanamin

B

2-Chlor-2-(chlorimino)-N-(difluor-λ4-sulfanyliden)-1,1-difluorethanamin
82878-40-8

2-Chlor-2-(chlorimino)-N-(difluor-λ4-sulfanyliden)-1,1-difluorethanamin

C

N,N-Dichlor-N'-(difluor-λ4-sulfanyliden)-1,1,2,2-tetrafluor-1,2-ethandiamin
32751-05-6

N,N-Dichlor-N'-(difluor-λ4-sulfanyliden)-1,1,2,2-tetrafluor-1,2-ethandiamin

D

Bis<2-<(difluor-λ4-sulfanyliden)amino>-1,1,2,2-tetrafluorethyl>diazen
82878-42-0

Bis<2-<(difluor-λ4-sulfanyliden)amino>-1,1,2,2-tetrafluorethyl>diazen

Conditions
ConditionsYield
With HgF3 at 140℃; for 1h; further reagent: BrF3;A n/a
B n/a
C n/a
D 91%
With bromine trifluoride at -15℃; Title compound not separated from byproducts;
1-methyl-piperazine
109-01-3

1-methyl-piperazine

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

3-chloro-4-(4-methylpiperazin-1-yl)-1,2,5-thiadiazole
870987-89-6

3-chloro-4-(4-methylpiperazin-1-yl)-1,2,5-thiadiazole

Conditions
ConditionsYield
In ethanol at 100℃; for 2.5h; Sealed tube; Microwave irradiation;91%
at 105 - 110℃; for 2.5h;90.2%
at 105 - 110℃; for 2.5h;90.2%
4-phenyl-1-piperazine
92-54-6

4-phenyl-1-piperazine

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

3-chloro-4-(4-phenylpiperazin-1-yl)-1,2,5-thiadiazole
1048981-72-1

3-chloro-4-(4-phenylpiperazin-1-yl)-1,2,5-thiadiazole

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 100 - 110℃;91%
at 105 - 110℃; for 2.5h;
4-phenylpiperidine
771-99-3

4-phenylpiperidine

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

Conditions
ConditionsYield
at 110 - 120℃;91%
3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

lithium hexamethyldisilazane
4039-32-1

lithium hexamethyldisilazane

C8H18ClN3SSi2

C8H18ClN3SSi2

Conditions
ConditionsYield
In n-heptane at -78℃; for 0.5h;90%
1,3-dimethyl-1,1,3,3-tetraphenyldisilazane
7453-26-1

1,3-dimethyl-1,1,3,3-tetraphenyldisilazane

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

C28H26ClN3SSi2

C28H26ClN3SSi2

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran at -10℃; for 0.5h;88%
pyrrolidine
123-75-1

pyrrolidine

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

3-(pyrrolidin-1-yl)-4-chloro-1,2,5-thiadiazole
173053-55-9

3-(pyrrolidin-1-yl)-4-chloro-1,2,5-thiadiazole

Conditions
ConditionsYield
at 22℃; Inert atmosphere;87%
titanium tetrachloride
7550-45-0

titanium tetrachloride

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

(SN2C2Cl2)2TiCl4
80044-97-9

(SN2C2Cl2)2TiCl4

Conditions
ConditionsYield
In dichloromethane under N2 and exclusion of air, to a soln. of SN2C2Cl2 in dry CH2Cl2 addn. of TiCl4 in CH2Cl2 under stirring at room temp.; removal of solvent, recrystn. (CH2Cl2), sublimation (vac., room temp.), elem. anal.;82%
decahydroisoquinoline
2744-08-3, 2744-09-4, 6329-61-9

decahydroisoquinoline

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

3-chloro-4-(octahydroisoquinolin-2(1H)-yl)-1,2,5-thiadiazole

3-chloro-4-(octahydroisoquinolin-2(1H)-yl)-1,2,5-thiadiazole

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 100 - 110℃;81%
3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

C2Cl2N2O3S2

C2Cl2N2O3S2

Conditions
ConditionsYield
With sulfur trioxide In dichloromethane Ambient temperature;79%
3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

1-t-Butoxycarbonylpiperazine
57260-71-6

1-t-Butoxycarbonylpiperazine

4-(4-chloro-[1,2,5]thiadiazol-3-yl)piperazine-1-carboxylic acid tert-butyl ester
291748-19-1

4-(4-chloro-[1,2,5]thiadiazol-3-yl)piperazine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
In N,N-dimethyl-formamide Heating;77%
With potassium carbonate In acetonitrile1.54 g (31%)
With diisopropylamine In N,N-dimethyl-formamide at 100℃; for 16h;2.7 g
With N-ethyl-N,N-diisopropylamine In dimethyl sulfoxide at 100℃; for 16h;
2-(trimethylsilyl)phenyl trifluoromethanesulfonate
88284-48-4

2-(trimethylsilyl)phenyl trifluoromethanesulfonate

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

Conditions
ConditionsYield
With cesium fluoride In tetrahydrofuran Reagent/catalyst; Solvent; Inert atmosphere;76%
1,1,3,3-tetramethyl-1,3-diphenyldisilazane
3449-26-1

1,1,3,3-tetramethyl-1,3-diphenyldisilazane

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

C18H22ClN3SSi2

C18H22ClN3SSi2

Conditions
ConditionsYield
With n-butyllithium In tetrahydrofuran at -10℃; for 0.5h;75%
3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

C19H26F3IO5SSi3

C19H26F3IO5SSi3

3-chloro-5,6-oxadisilole-1,2-benzoisothiazole

3-chloro-5,6-oxadisilole-1,2-benzoisothiazole

Conditions
ConditionsYield
Stage #1: C19H26F3IO5SSi3 With cesium fluoride
Stage #2: 3,4-dichloro-1,2,5-thiadiazole In tetrahydrofuran at 60℃; for 3h;
75%
2,2,6,6-tetramethyl-piperidine
768-66-1

2,2,6,6-tetramethyl-piperidine

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

2-chloro-2-(2,2,6,6-tetramethyl-1-piperidinylthio)iminoacetonitrile
895167-58-5

2-chloro-2-(2,2,6,6-tetramethyl-1-piperidinylthio)iminoacetonitrile

Conditions
ConditionsYield
Stage #1: 2,2,6,6-tetramethyl-piperidine With n-butyllithium In tert-butyl methyl ether at -20℃;
Stage #2: 3,4-dichloro-1,2,5-thiadiazole In tert-butyl methyl ether at -50℃;
74%
3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

KF

KF

A

3,4-Difluoro-1,2,5-thiadiazole
82878-37-3

3,4-Difluoro-1,2,5-thiadiazole

B

3-chloro-4-fluoro-1,2,5-thiadiazole
82878-38-4

3-chloro-4-fluoro-1,2,5-thiadiazole

Conditions
ConditionsYield
In sulfolane at 180℃; for 10h;A 73%
B 24%
In sulfolane at 180℃; for 10h; further reagent: 18-Crown<6>, XeF2;A 48%
B 24%
3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

lithium hexamethyldisilazane
4039-32-1

lithium hexamethyldisilazane

2-chloro-2-(N,N-bis(trimethylsilyl)aminothio)iminoacetonitrile
895167-57-4

2-chloro-2-(N,N-bis(trimethylsilyl)aminothio)iminoacetonitrile

Conditions
ConditionsYield
In tetrahydrofuran; diethyl ether; cyclohexane at -78℃; for 1h;73%
3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

2-methoxy-6-(trimethylsilyl)phenyltrifluoromethanesulfonate
881009-83-2

2-methoxy-6-(trimethylsilyl)phenyltrifluoromethanesulfonate

3-chloro-4-methoxy-1,2-benzoisothiazole
103486-06-2

3-chloro-4-methoxy-1,2-benzoisothiazole

Conditions
ConditionsYield
With cesium fluoride In tetrahydrofuran Inert atmosphere; regioselective reaction;70%
4-bromo-2-methoxy-6-(trimethylsilyl)phenyl trifluoromethanesulfonate

4-bromo-2-methoxy-6-(trimethylsilyl)phenyl trifluoromethanesulfonate

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

A

3-chloro-4-methoxy-6-bromo-1,2-benzoisothiazole

3-chloro-4-methoxy-6-bromo-1,2-benzoisothiazole

B

3-chloro-5-bromo-7-methoxy-1,2-benzoisothiazole

3-chloro-5-bromo-7-methoxy-1,2-benzoisothiazole

Conditions
ConditionsYield
With cesium fluoride In tetrahydrofuran Inert atmosphere; regioselective reaction;A 69%
B 9%
2-(trimethylsilyl)phenyl trifluoromethanesulfonate
88284-48-4

2-(trimethylsilyl)phenyl trifluoromethanesulfonate

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

A

3-Amino-benzo[b]thiophene-2-carboxylic acid methyl ester
35212-85-2

3-Amino-benzo[b]thiophene-2-carboxylic acid methyl ester

B

dimethyl 2,1-benzoisothiazole-3-malonate

dimethyl 2,1-benzoisothiazole-3-malonate

Conditions
ConditionsYield
Stage #1: 2-(trimethylsilyl)phenyl trifluoromethanesulfonate; 3,4-dichloro-1,2,5-thiadiazole With cesium fluoride In tetrahydrofuran at 20 - 65℃; Inert atmosphere;
Stage #2: malonic acid dimethyl ester With sodium methylate In tetrahydrofuran at 20℃; for 12h; Inert atmosphere;
A 11%
B 68%
3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

3,6-dimethyl-2-(trimethylsilyl)phenyl triflate
780820-44-2

3,6-dimethyl-2-(trimethylsilyl)phenyl triflate

3-chloro-4,7-dimethyl-1,2-benzoisothiazole

3-chloro-4,7-dimethyl-1,2-benzoisothiazole

Conditions
ConditionsYield
With cesium fluoride In tetrahydrofuran Inert atmosphere;67%

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