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NANJING SUNNY PHARMATECH CO., LTD

Our product has a very high quality and now we are exporting to customers overseas with very positive feedback. With best price, quality and service from Nanjing Sunny, we are confident to set up a very nice cooperation with customers all over the w

3-Chloro-1,2-benzisothiazole

Cas:7716-66-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

3-Chloro-1,2-benzisothiazole Manufacturer/High quality/Best price/In stock

Cas:7716-66-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 3-Chloro-1,2-Benzisothiazole supplier in China

Cas:7716-66-7

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

3-Chloro-1,2-benzisothiazole

Cas:7716-66-7

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 3-Chloro-1,2-Benzisothiazole

Cas:7716-66-7

Min.Order:1

Negotiable

Type:Other

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3-Chloro-1,2-benzisothiazole

Cas:7716-66-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

3-Chloro-1,2-benzisothiazole Basic information Product Name: 3-Chloro-1,2-benzisothiazole Synonyms: 3-CHLORO-1,2-BENZISOTHIAZOLE;3-CHLORO-1,2-BENZOISOTHIAZOLE;3-CHLORO-BENZO[D]ISOTHIAZOL

3-Chloro-1,2-benzisothiazole

Cas:7716-66-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

3-Chloro-1,2-benzisothiazole

Cas:7716-66-7

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 7716-66-7 with best quality

Cas:7716-66-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after the dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available &diam

3-Chloro-1,2-benzisothiazole CAS7716-66-7

Cas:7716-66-7

Min.Order:1 Kilogram

FOB Price: $7.0 / 10.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product name 3-Chloro-1,2-benzisothiazole CAS 7716-66-7 Synonyms 3-CHLORO-1,2-BENZISOTHIAZOLE;3-CHLORO-1,2-BENZOISOTHIAZOLE;3-CHLORO-BENZO[D]ISOTHIAZOLE;3-CHLOROBENZISOTHIAZO

3-Chloro-1,2-benzisothiazole CAS: 7716-66-7

Cas:7716-66-7

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:white or off-white powder Storage:Store in sealed containers

3-Chloro-1,2-benzisothiazole CAS 7716-66-7

Cas:7716-66-7

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1,2-Benzisothiazole,3-chloro- 7716-66-7

Cas:7716-66-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

3-Chloro-1,2-benzisothiazole CAS:7716-66-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality orga

3-Chloro-1,2-benzisothiazole CAS:7716-66-7

Cas:7716-66-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1,2-Benzisothiazole,3-chloro-

Cas:7716-66-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

1,2-Benzisothiazole,3-chloro-/ LIDE PHARMA- Factory supply / Best price

Cas:7716-66-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:7716-66-7

Cas:7716-66-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

3-Chloro-1,2-Benzisothiazole

Cas:7716-66-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Service 1.Own made fine chemical products 2.Out sourcing and quality c

3-Chloro-1,2-benzisothiazole

Cas:7716-66-7

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3-Chloro-1,2-benzisothiazole

Cas:7716-66-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products 3-Chloro-1,2-benzisothiazole

Cas:7716-66-7

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 3-Chloro-1,2-Benzisothiazole

Cas:7716-66-7

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

3-Chloro-1,2-benzisothiazole CAS NO.7716-66-7Appearance:White Solid Storage:Well-ventilating, away from open fire, high temperature, and Antioxidant. Package:according to customers' requirements Application:Pharmaceutical Intermediate Transportation:

3-Chloro-1,2-benzisothiazole CAS NO.7716-66-7

Cas:7716-66-7

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:light yellow crystal powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum, or as per your request. Application:For medicine , pest

3-Chloro-1,2-benzisothiazole

Cas:7716-66-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

3-Chloro-1,2-benzisothiazole

Cas:7716-66-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

BEST PRICE/3-Chloro-1,2-benzisothiazole CAS NO.7716-66-7 CAS NO.7716-66-7

Cas:7716-66-7

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

3-Chloro-1,2-benzoisothiazole

Cas:7716-66-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

3-Chloro-1,2-benzisothiazole

Cas:7716-66-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

3-Chloro-1,2-benzisothiazole CAS NO.7716-66-7

Cas:7716-66-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

3-Chloro-1,2-benzisothiazole cas no. 7716-66-7 98%%

Cas:7716-66-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

1,2-benzisothiazolin-3-one
2634-33-5

1,2-benzisothiazolin-3-one

3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

Conditions
ConditionsYield
In chlorobenzene; paraffin oil92.7%
With thionyl chloride; N,N-dimethyl-formamide In chlorobenzene at 70 - 80℃; for 9h;90%
With tetramethylurea In chlorobenzene84.9%
2-(trimethylsilyl)phenyl trifluoromethanesulfonate
88284-48-4

2-(trimethylsilyl)phenyl trifluoromethanesulfonate

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

Conditions
ConditionsYield
With cesium fluoride In tetrahydrofuran Reagent/catalyst; Solvent; Inert atmosphere;76%
benzenedizolium-2-carboxylate
1608-42-0

benzenedizolium-2-carboxylate

3,4-dichloro-1,2,5-thiadiazole
5728-20-1

3,4-dichloro-1,2,5-thiadiazole

A

3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

B

ClCN

ClCN

Conditions
ConditionsYield
In tetrahydrofuran for 0.5h; Heating;A 35%
B n/a
1,2-benzisothiazol-3-one
2634-33-5

1,2-benzisothiazol-3-one

3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

Conditions
ConditionsYield
With triethylamine; trichlorophosphate
3-Chlor-2-methyl-1,2-benzisothiazoliumchlorid
4163-05-7

3-Chlor-2-methyl-1,2-benzisothiazoliumchlorid

3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

1.2-benzisothiazolone

1.2-benzisothiazolone

3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

Conditions
ConditionsYield
With phosphorus pentachloride; trichlorophosphate at 130 - 140℃;
2,2'-dithiodibenzoic acid dichloride
19602-82-5

2,2'-dithiodibenzoic acid dichloride

3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: Cl2 / CH2Cl2
2: concd NH4OH / CH2Cl2 / 1 h
3: 77 percent / POCl3 / 3.5 h / 20 - 120 °C
View Scheme
2,2'-dithiobenzoic acid
119-80-2

2,2'-dithiobenzoic acid

3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 71 percent / SOCl2 / dimethylformamide; toluene / 18 h / 75 °C
2: Cl2 / CH2Cl2
3: concd NH4OH / CH2Cl2 / 1 h
4: 77 percent / POCl3 / 3.5 h / 20 - 120 °C
View Scheme
2-chlorosulfenylbenzoyl chloride
3950-02-5

2-chlorosulfenylbenzoyl chloride

3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: concd NH4OH / CH2Cl2 / 1 h
2: 77 percent / POCl3 / 3.5 h / 20 - 120 °C
View Scheme
anthranilic acid
118-92-3

anthranilic acid

3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: pentyl nitrile
2: 35 percent / tetrahydrofuran / 0.5 h / Heating
View Scheme
1,2-benzisothiazolin-3-one
2634-33-5

1,2-benzisothiazolin-3-one

water
7732-18-5

water

3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

Conditions
ConditionsYield
With trichlorophosphate
3-methoxy-1,2-benzoisothiazole
40991-38-6

3-methoxy-1,2-benzoisothiazole

3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

Conditions
ConditionsYield
With tributyl-amine; trichlorophosphate at 20 - 115℃;6.97 g
3-methoxy-4-chloro-1,2,5-thiadiazole
5728-16-5

3-methoxy-4-chloro-1,2,5-thiadiazole

2-(trimethylsilyl)phenyl trifluoromethanesulfonate
88284-48-4

2-(trimethylsilyl)phenyl trifluoromethanesulfonate

A

3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

B

3-methoxy-1,2-benzoisothiazole
40991-38-6

3-methoxy-1,2-benzoisothiazole

Conditions
ConditionsYield
With cesium fluoride In tetrahydrofuran at 60℃; Inert atmosphere; Overall yield = 75 %;
3-Morpholino-4-chloro-1,2,5-thiadiazole
30165-96-9

3-Morpholino-4-chloro-1,2,5-thiadiazole

2-(trimethylsilyl)phenyl trifluoromethanesulfonate
88284-48-4

2-(trimethylsilyl)phenyl trifluoromethanesulfonate

A

3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

B

3-(morpholin-4-yl)-1,2-benzoisothiazole
22801-59-8

3-(morpholin-4-yl)-1,2-benzoisothiazole

Conditions
ConditionsYield
With cesium fluoride In tetrahydrofuran at 60℃; Inert atmosphere; Overall yield = 83 %;
2-Chlorobenzonitrile
873-32-5

2-Chlorobenzonitrile

3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: tetrabutylammomium bromide; sodium hydroxide; Octanethiol / chlorobenzene; water / 4 h / 65 - 70 °C / Inert atmosphere
2: thionyl chloride / chlorobenzene; N,N-dimethyl-formamide / 10 h / 75 °C
View Scheme
2-cyanothioanisole
6609-54-7

2-cyanothioanisole

3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hydrogenchloride; chlorine / chlorobenzene; water / 1.5 h / 25 - 65 °C
2: trichlorophosphate / N,N-dimethyl-formamide; toluene / 3.5 h / 0 - 60 °C / Inert atmosphere
View Scheme
3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

4-[4-(4-chloro-phenyl)-5-methyl-4H-[1,2,4]triazol-3-yl]-piperidine
859154-07-7

4-[4-(4-chloro-phenyl)-5-methyl-4H-[1,2,4]triazol-3-yl]-piperidine

3-{4-[4-(4-chlorophenyl)-5-methyl-4H-1,2,4-triazol-3-yl]piperidin-1-yl}-1,2-benzisothiazole

3-{4-[4-(4-chlorophenyl)-5-methyl-4H-1,2,4-triazol-3-yl]piperidin-1-yl}-1,2-benzisothiazole

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile at 20℃; for 48h;98%
piperazine
110-85-0

piperazine

3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

1-(2-cyanophenylthio)piperazine

1-(2-cyanophenylthio)piperazine

Conditions
ConditionsYield
In tetrahydrofuran at 60 - 65℃; for 17h; Inert atmosphere;89%
3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

Methyl phenyldiazoacetate
22979-35-7

Methyl phenyldiazoacetate

methyl 4-chloro-2-phenyl-2H-benzo[e][1,3]thiazine-2-carboxylate
1044822-25-4

methyl 4-chloro-2-phenyl-2H-benzo[e][1,3]thiazine-2-carboxylate

Conditions
ConditionsYield
dirhodium tetraacetate In dichloromethane for 0.25h; Heating;88%
3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

3-Amino-benzo[b]thiophene-2-carboxylic acid methyl ester
35212-85-2

3-Amino-benzo[b]thiophene-2-carboxylic acid methyl ester

Conditions
ConditionsYield
Stage #1: malonic acid dimethyl ester With sodium methylate In methanol for 0.0833333h; Inert atmosphere;
Stage #2: 3-chloro-1,2-benzisothiazole In methanol at 20℃; for 0.5h; Reagent/catalyst; Inert atmosphere;
88%
3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

o-trifluoromethylphenyl bromide
392-83-6

o-trifluoromethylphenyl bromide

3-(2-trifluoromethylphenyl)benzisothiazole
1393880-01-7

3-(2-trifluoromethylphenyl)benzisothiazole

Conditions
ConditionsYield
Stage #1: o-trifluoromethylphenyl bromide With n-butyllithium; Triisopropyl borate In tetrahydrofuran; hexane at -78℃; for 1h; Inert atmosphere;
Stage #2: 3-chloro-1,2-benzisothiazole With potassium phosphate; chloro-(2-dicyclohexylphosphino-2,4,6-triisopropyl-1,1-biphenyl)[2-(2-amino-1,1-biphenyl)]palladium(II) In tetrahydrofuran; hexane; water at 40℃; for 2h; Suzuki-Miyaura Coupling; Inert atmosphere;
87%
piperazine
110-85-0

piperazine

3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

3-(1-piperazinyl)-1,2-benzisothiazole
87691-87-0

3-(1-piperazinyl)-1,2-benzisothiazole

Conditions
ConditionsYield
In ethanol at 80℃; for 36h;85%
In ethanol at 80℃; for 18h;79.6%
at 125℃; for 24h;68%
3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

1-phenoxy-2-propanol
770-35-4

1-phenoxy-2-propanol

3-((1-phenoxypropan-2-yl)oxy)benzo[d]isothiazole

3-((1-phenoxypropan-2-yl)oxy)benzo[d]isothiazole

Conditions
ConditionsYield
With C52H70NO5PPdS; sodium t-butanolate In tetrahydrofuran at 20℃; for 18h; Sealed tube; Schlenk technique;81%
3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

phenylacetonitrile
140-29-4

phenylacetonitrile

2-fenil-2-(1,2-benzisotiazol-3-il)acetonitrile
86004-79-7

2-fenil-2-(1,2-benzisotiazol-3-il)acetonitrile

Conditions
ConditionsYield
With sodium ethanolate In ethanol for 2h; Heating;80%
With sodium ethanolate
piperazine
110-85-0

piperazine

3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

3-(1-piperazinyl)-1,2-benzisothiazole hydrochloride
87691-88-1

3-(1-piperazinyl)-1,2-benzisothiazole hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In water; isopropyl alcohol; toluene; tert-butyl alcohol80%
With hydrogenchloride In water; toluene; tert-butyl alcohol80%
With hydrogenchloride In water; isopropyl alcohol; toluene; tert-butyl alcohol80%
3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

acetylacetone
123-54-6

acetylacetone

2-acetyl-3-aminobenzothiophen
34263-61-1

2-acetyl-3-aminobenzothiophen

Conditions
ConditionsYield
Stage #1: acetylacetone With sodium ethanolate In ethanol for 0.333333h;
Stage #2: 3-chloro-1,2-benzisothiazole In ethanol at 20℃; for 16h;
80%
3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

2-propylzinc bromide lithium chloride

2-propylzinc bromide lithium chloride

3-isopropyl-benzo[d]isothiazole

3-isopropyl-benzo[d]isothiazole

Conditions
ConditionsYield
With 2′-(dicyclohexylphophanyl)-N2,N2,N6,N6-tetramethyl[1,1′-biphenyl]-2,6-diamine; C13H13NO3PdS In tetrahydrofuran; toluene at 0 - 20℃; for 1h; Negishi Coupling; Inert atmosphere;78%
3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

diethyl malonate
105-53-3

diethyl malonate

ethyl 3-aminobenzothiophene-2-carboxylate
34761-09-6

ethyl 3-aminobenzothiophene-2-carboxylate

Conditions
ConditionsYield
Stage #1: diethyl malonate With sodium ethanolate In ethanol for 0.333333h; Inert atmosphere; Cooling with ice;
Stage #2: 3-chloro-1,2-benzisothiazole In ethanol for 24h; Inert atmosphere;
76%
Stage #1: diethyl malonate With sodium ethanolate In ethanol for 0.333333h; Inert atmosphere; Cooling with ice;
Stage #2: 3-chloro-1,2-benzisothiazole In ethanol for 24h; Inert atmosphere;
76%
Stage #1: diethyl malonate With sodium ethanolate In ethanol for 0.333333h; Cooling with ice; Inert atmosphere;
Stage #2: 3-chloro-1,2-benzisothiazole In ethanol for 24h; Inert atmosphere;
76%
piperidine
110-89-4

piperidine

3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

3-(piperidin-1-yl)-1,2-benzoisothiazole
22801-60-1

3-(piperidin-1-yl)-1,2-benzoisothiazole

Conditions
ConditionsYield
Reflux;70.8%
3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

p-chlorobenzyl cyanide
140-53-4

p-chlorobenzyl cyanide

2-(4-clorofenil)-2-(1,2-benzisotiazol-3-il)acetonitrile
87792-16-3

2-(4-clorofenil)-2-(1,2-benzisotiazol-3-il)acetonitrile

Conditions
ConditionsYield
With sodium ethanolate In ethanol for 2h; Heating;70%
piperazine
110-85-0

piperazine

3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

A

3,3'-(1,4-piperazinyl)-1,2-benzisothiazole

3,3'-(1,4-piperazinyl)-1,2-benzisothiazole

B

3-(1-piperazinyl)-1,2-benzisothiazole hydrochloride
87691-88-1

3-(1-piperazinyl)-1,2-benzisothiazole hydrochloride

Conditions
ConditionsYield
With pyridine at 115 - 119℃; for 25h; Temperature; Solvent; Inert atmosphere;A n/a
B 67%
3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

3,4-dichloro-benzeneacetonitrile
3218-49-3

3,4-dichloro-benzeneacetonitrile

2-(3,4-diclorofenil)-2-(1,2-benzisotiazol-3-il)acetonitrile
87792-17-4

2-(3,4-diclorofenil)-2-(1,2-benzisotiazol-3-il)acetonitrile

Conditions
ConditionsYield
With sodium ethanolate In ethanol for 2h; Heating;65%
3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

3,4-dihydro-7-methoxybenzofuro[2,3-c]pyridine-2(1H)-butanamine
263544-12-3

3,4-dihydro-7-methoxybenzofuro[2,3-c]pyridine-2(1H)-butanamine

butan-1-ol
71-36-3

butan-1-ol

N-(1,2-benzisothiazol-3-yl)-3,4-dihydro-7-methoxybenzofuro[2,3-c]pyridine-2(1H)-butanamine monohydrochloride monohydrate

N-(1,2-benzisothiazol-3-yl)-3,4-dihydro-7-methoxybenzofuro[2,3-c]pyridine-2(1H)-butanamine monohydrochloride monohydrate

Conditions
ConditionsYield
With sodium hydrogencarbonate In dichloromethane; acetone61%
3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

3,4-dimethoxyphenylacetonitrile
93-17-4

3,4-dimethoxyphenylacetonitrile

Benzo[d]isothiazol-3-yl-(3,4-dimethoxy-phenyl)-acetonitrile

Benzo[d]isothiazol-3-yl-(3,4-dimethoxy-phenyl)-acetonitrile

Conditions
ConditionsYield
With sodium ethanolate In ethanol for 2h; Heating;60%
3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

C12H15BrO2Zn

C12H15BrO2Zn

4-(benzo[d]isothiazol-3-yl)pentyl benzoate

4-(benzo[d]isothiazol-3-yl)pentyl benzoate

Conditions
ConditionsYield
With [1,3-bis(2,6-diisoheptylphenyl)-4,5-dichloroimidazol-2-ylidene](3-chloropyridyl)palladium(II) dichloride In tetrahydrofuran; toluene at 0 - 23℃; Negishi Coupling; Inert atmosphere; Schlenk technique;59%
3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

3-aminobenzisothiazole
23031-78-9

3-aminobenzisothiazole

Conditions
ConditionsYield
With ammonia In formamide at 130℃; for 0.75h;58%
3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

dimethyl 2,1-benzoisothiazole-3-malonate

dimethyl 2,1-benzoisothiazole-3-malonate

Conditions
ConditionsYield
With sodium acetate In tetrahydrofuran; ethanol at 20℃; for 24.5h; Inert atmosphere; Reflux;57%
3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

p-methoxybenzylnitrile
104-47-2

p-methoxybenzylnitrile

Benzo[d]isothiazol-3-yl-(4-methoxy-phenyl)-acetonitrile

Benzo[d]isothiazol-3-yl-(4-methoxy-phenyl)-acetonitrile

Conditions
ConditionsYield
With sodium ethanolate In ethanol for 2h; Heating;45%
3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

[3,3']bi[benzo[d]isothiazolyl]

[3,3']bi[benzo[d]isothiazolyl]

Conditions
ConditionsYield
With piperazine at 120℃; for 24h;30.8%
3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

A

3,5-dibromo-1,2-benzisothiazole

3,5-dibromo-1,2-benzisothiazole

B

3,7-dibromo-1,2-benzisothiazole
155167-97-8

3,7-dibromo-1,2-benzisothiazole

Conditions
ConditionsYield
With bromine; iron(III) chloride In acetic acid for 20h; Heating;A n/a
B 18%
3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

3-chloro-7-nitro-1,2-benzisothiazole
41533-75-9

3-chloro-7-nitro-1,2-benzisothiazole

Conditions
ConditionsYield
With sulfuric acid; potassium nitrate at 0℃; for 3h;15%
With sulfuric acid; potassium nitrate at 0 - 26℃; for 12h;220 mg
3-chloro-1,2-benzisothiazole
7716-66-7

3-chloro-1,2-benzisothiazole

8-<4-(3-methyl-1-piperazinyl)butyl>-8-azaspiro<4.5>decane-7,9-dione
80827-65-2

8-<4-(3-methyl-1-piperazinyl)butyl>-8-azaspiro<4.5>decane-7,9-dione

8-<4-<4-(1,2-benzisothiazol-3-yl)-3-methyl-1-piperazinyl>butyl>-8-azaspiro<4.5>decane-7,9-dione
99748-55-7

8-<4-<4-(1,2-benzisothiazol-3-yl)-3-methyl-1-piperazinyl>butyl>-8-azaspiro<4.5>decane-7,9-dione

Conditions
ConditionsYield
at 120℃; for 16h;8%

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