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TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed product

1,2,3-Trifluoro-4-nitrobenzene

Cas:771-69-7

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

2,3,4-Trifluoronitrobenzene Manufacturer/High quality/Best price/In stock

Cas:771-69-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2,3,4-Trifluoronitrobenzene supplier in China

Cas:771-69-7

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

1,2,3-Trifluoro-4-nitrobenzene

Cas:771-69-7

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2,3,4-Trifluoro Nitro Benzene

Cas:771-69-7

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price OLED 99% 771-69-7 1,2,3-Trifluoro-4-nitrobenzene Manufacturer

Cas:771-69-7

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

1,2,3-Trifluoro-4-nitrobenzene

Cas:771-69-7

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

2, 3, 4-Trifluoronitrobenzene

Cas:771-69-7

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

2,3,4-Trifluoronitrobenzene -- CHemwill

Cas:771-69-7

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

2,3,4-Trifluoronitrobenzene

Cas:771-69-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 771-69-7 with fast shipping

Cas:771-69-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:Liquid Storage:Store in sealed containers at cool & dry plac

High quality Benzene,1,2,3-trifluoro-4-nitro- CAS 771-69-7

Cas:771-69-7

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2,3,4-Trifluoronitrobenzene 771-69-7

Cas:771-69-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Ofloxacin intermediate, 1,2,3-Trifluoro-4-nitrobenzene CAS:771-69-7

Cas:771-69-7

Min.Order:1 Kilogram

FOB Price: $42.0 / 48.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

1,2,3-Trifluoro-4-nitrobenzene CAS:771-69-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality org

1,2,3-Trifluoro-4-nitrobenzene CAS:771-69-7

Cas:771-69-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2,3,4-Trifluoronitrobenzene

Cas:771-69-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:771-69-7

Cas:771-69-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2,3,4-Trifluoronitrobenzene

Cas:771-69-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

771-69-7

Cas:771-69-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1,2,3-Trifluoro-4-nitrobenzene

Cas:771-69-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2,3,4-Trifluoronitrobenzene

Cas:771-69-7

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

2,3,4-TrifluoronitrobenzeneAppearance:transparent to light yellow liquid Storage:In Shade Package:according to customers' requirements Application:pharmaceutical intermediate Transportation:By air(EMS or EUB or FedEx or TNT ect...) or by sea(FOB or

2,3,4-Trifluoronitrobenzene

Cas:771-69-7

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Best Offer1,2,3-Trifluoro-4-nitrobenzene

Cas:771-69-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

2,3,4-Trifluoronitrobenzene

Cas:771-69-7

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

1,2,3-Trifluoro-4-nitrobenzene Basic information Product Name: 1,2,3-Trifluoro-4-nitrobenzene Synonyms: 3,4,5 TRIFLUORONITROBENZEN;2,3,4-Trifluornitrobenzene;4-chloro-2-fluroaniline;2,3,4-TRIFLUORONITROBRNZENE;1-nitro-2,3,4-trifluorobenzene;2,

1,2,3-Trifluoro-4-nitrobenzene

Cas:771-69-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

1-nitro-2,3,4-trifluorobenzene

Cas:771-69-7

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

1-nitro-2,3,4-trifluorobenzene

Cas:771-69-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

1-nitro-2,3,4-trifluorobenzene

Cas:771-69-7

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

2,3,4-Trifluoronitrobenzene

Cas:771-69-7

Min.Order:0

Negotiable

Type:Other

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

2,3,4-Trifluoronitrobenzene

Cas:771-69-7

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

4-nitro-1,2,3-trichlorobenzene
17700-09-3

4-nitro-1,2,3-trichlorobenzene

2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

Conditions
ConditionsYield
Stage #1: 4-nitro-1,2,3-trichlorobenzene With potassium fluoride; tetrabutylammomium bromide In dimethyl sulfoxide at 75 - 80℃; for 4h;
Stage #2: With potassium fluoride; tetrabutyl ammonium fluoride In dimethyl sulfoxide at 75 - 180℃; for 12h; Time;
99.7%
1,3-dichloro-2-fluorobenzene
2268-05-5

1,3-dichloro-2-fluorobenzene

2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

Conditions
ConditionsYield
Stage #1: 1,3-dichloro-2-fluorobenzene With sulfuric acid; nitric acid at 20 - 25℃; for 2.5h;
Stage #2: With sulfolane; potassium fluoride for 5h;
85.5%
Multi-step reaction with 2 steps
1: sulfuric acid; aqueous nitric acid / 40 °C
2: dimethylformamide; potassium fluoride / 150 °C
View Scheme
Multi-step reaction with 2 steps
1: sulfuric acid; nitric acid / 2 h / Heating
2: sulfolane; potassium fluoride / 8 h / 200 - 210 °C
View Scheme
1,3-dichloro-2-fluoro-4-nitrobenzene
393-79-3

1,3-dichloro-2-fluoro-4-nitrobenzene

2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

Conditions
ConditionsYield
With potassium fluoride at 160 - 165℃; for 7h; Time;85%
With potassium fluoride; immobilized pyridinium salt In sulfolane at 180℃; for 2h;68%
With potassium fluoride; N,N-dimethyl-formamide at 150℃;
With sulfolane; potassium fluoride at 200 - 210℃; for 8h; Temperature;124 g
1,2,3-trifluorobenzene
1489-53-8

1,2,3-trifluorobenzene

2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

3,4,5-trifluoro aniline
163733-96-8

3,4,5-trifluoro aniline

2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: tetrahydrofuran
View Scheme
anhydrous ethylene glycol dimethyl ether

anhydrous ethylene glycol dimethyl ether

trimethyl(ethoxypolyoxypropylmethyl ether)ammonium chloride

trimethyl(ethoxypolyoxypropylmethyl ether)ammonium chloride

1,3-dichloro-2-fluoro-4-nitrobenzene
393-79-3

1,3-dichloro-2-fluoro-4-nitrobenzene

tetrabutyl phosphonium bromide
3115-68-2

tetrabutyl phosphonium bromide

2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

Conditions
ConditionsYield
With potassium fluoride In 5,5-dimethyl-1,3-cyclohexadiene
1,2-dichloro-benzene
95-50-1

1,2-dichloro-benzene

2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: nitric acid; sulfuric acid / 2 h / 95 - 100 °C
2.1: potassium fluoride / 3 h / 140 - 150 °C
3.1: chlorine / 180 - 190 °C
4.1: nitric acid; sulfuric acid / 2.5 h / 20 - 25 °C
4.2: 5 h
View Scheme
1,2-Dichloro-3-nitrobenzene
3209-22-1

1,2-Dichloro-3-nitrobenzene

2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: potassium fluoride / 3 h / 140 - 150 °C
2.1: chlorine / 180 - 190 °C
3.1: nitric acid; sulfuric acid / 2.5 h / 20 - 25 °C
3.2: 5 h
View Scheme
1-chloro-2-fluoro-3-nitrobenzene
2106-49-2

1-chloro-2-fluoro-3-nitrobenzene

2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: chlorine / 180 - 190 °C
2.1: nitric acid; sulfuric acid / 2.5 h / 20 - 25 °C
2.2: 5 h
View Scheme
3,4,5-trichloronitrobenzen
20098-48-0

3,4,5-trichloronitrobenzen

2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: potassium fluoride; N-benzyl-N,N,N-triethylammonium chloride / 11 h / 140 - 175 °C
2.1: hydrogen / methanol / Inert atmosphere
3.1: nitrosylsulfuric acid / 6 h / 10 - 15 °C
3.2: 1 h
4.1: sulfuric acid; nitric acid / 2 h / Heating
5.1: sulfolane; potassium fluoride / 8 h / 200 - 210 °C
View Scheme
3,5-dichloro-4-fluoro-nitrobenzene
3107-19-5

3,5-dichloro-4-fluoro-nitrobenzene

2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: hydrogen / methanol / Inert atmosphere
2.1: nitrosylsulfuric acid / 6 h / 10 - 15 °C
2.2: 1 h
3.1: sulfuric acid; nitric acid / 2 h / Heating
4.1: sulfolane; potassium fluoride / 8 h / 200 - 210 °C
View Scheme
3,5-dichloro-4-fluorophenylamine
2729-34-2

3,5-dichloro-4-fluorophenylamine

2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: nitrosylsulfuric acid / 6 h / 10 - 15 °C
1.2: 1 h
2.1: sulfuric acid; nitric acid / 2 h / Heating
3.1: sulfolane; potassium fluoride / 8 h / 200 - 210 °C
View Scheme
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

2,3,4-trifluoro-5-(trimethylsilyl)nitrobenzene

2,3,4-trifluoro-5-(trimethylsilyl)nitrobenzene

Conditions
ConditionsYield
With sodium hexamethyldisilazane In tetrahydrofuran at -78℃;100%
2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

(R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol
100-79-8

(R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol

(R)-3,4-difluoro-2-(2,3-isopropylidenedioxypropoxy)nitrobenzene
129798-33-0

(R)-3,4-difluoro-2-(2,3-isopropylidenedioxypropoxy)nitrobenzene

Conditions
ConditionsYield
With potassium hydroxide In water; toluene100%
3,5-dibromophenol
626-41-5

3,5-dibromophenol

2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

C12H5Br2F2NO3
930786-23-5

C12H5Br2F2NO3

Conditions
ConditionsYield
With sodium t-butanolate In tetrahydrofuran at 0 - 20℃;100%
2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

aniline
62-53-3

aniline

(2,3-Difluoro-6-nitro-phenyl)-phenylamine
1393178-31-8

(2,3-Difluoro-6-nitro-phenyl)-phenylamine

Conditions
ConditionsYield
Stage #1: aniline With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 0.166667h; Inert atmosphere;
Stage #2: 2,3,4-trifluoronitrobenzene In tetrahydrofuran at -78℃; for 0.5h;
Stage #3: With water In tetrahydrofuran
100%
2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

sodium methylate
124-41-4

sodium methylate

2-fluoro-1,3-dimethoxy-4-nitrobenzene
155020-44-3

2-fluoro-1,3-dimethoxy-4-nitrobenzene

Conditions
ConditionsYield
In methanol Ambient temperature;99%
In methanol at 4 - 20℃; for 0.5h;99%
In methanol at 0 - 20℃;98%
In methanol at 0 - 20℃;80%
2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

methylamine
74-89-5

methylamine

2,3-difluoro-N-methyl-6-nitroaniline
170432-54-9

2,3-difluoro-N-methyl-6-nitroaniline

Conditions
ConditionsYield
In tetrahydrofuran at 40℃; for 18h;99%
2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

2,3,4-trifluoroaniline
3862-73-5

2,3,4-trifluoroaniline

Conditions
ConditionsYield
With sodium hypophosphite monohydrate; 1% platinum on charcoal; hydrogen at 65 - 80℃; under 6750.68 Torr; for 2.75h; Reagent/catalyst; Temperature; Autoclave;98.52%
With hydrogen; nickel Autoclave;91.8%
With iron; ammonium chloride
1,5-dioxaspiro[5.5]undecane-2,4-dione
1658-27-1

1,5-dioxaspiro[5.5]undecane-2,4-dione

2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

N-ethyl-N,N-diisopropylamine
7087-68-5

N-ethyl-N,N-diisopropylamine

C15H13F2NO6*C8H19N

C15H13F2NO6*C8H19N

Conditions
ConditionsYield
In acetonitrile at 45℃; for 20h;98%
2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

1,2,3-Trifluoro-4,6-dinitrobenzene
55346-93-5

1,2,3-Trifluoro-4,6-dinitrobenzene

Conditions
ConditionsYield
With trifluorormethanesulfonic acid; tris(trifluoromethanesulfonyloxy)boron; nitric acid at 65℃; for 6h;96%
With sulfuric acid; potassium nitrate91%
With sulfuric acid; nitric acid at 80℃; for 2h;84.2%
2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

1-(4-fluoro-phenyl)-2-(tetrahydro-pyrimidin-2-ylidene)-ethanone
251940-05-3

1-(4-fluoro-phenyl)-2-(tetrahydro-pyrimidin-2-ylidene)-ethanone

6-fluoro-10-(4-fluorobenzoyl)-9-nitro-1,2,3,4-tetrahydropyrimido[1,2-a]indole

6-fluoro-10-(4-fluorobenzoyl)-9-nitro-1,2,3,4-tetrahydropyrimido[1,2-a]indole

Conditions
ConditionsYield
Stage #1: 2,3,4-trifluoronitrobenzene; 1-(4-fluoro-phenyl)-2-(tetrahydro-pyrimidin-2-ylidene)-ethanone With sodium carbonate In 1,4-dioxane at 80℃; for 4h;
Stage #2: With caesium carbonate In 1,4-dioxane for 3h; Reflux;
93%
2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

1-phenyl-2-(tetrahydropyrimidin-2(1H)-ylidene)ethan-1-one
82100-30-9

1-phenyl-2-(tetrahydropyrimidin-2(1H)-ylidene)ethan-1-one

10-benzoyl-6-fluoro-9-nitro-1,2,3,4-tetrahydropyrimido[1,2-a]indole

10-benzoyl-6-fluoro-9-nitro-1,2,3,4-tetrahydropyrimido[1,2-a]indole

Conditions
ConditionsYield
Stage #1: 2,3,4-trifluoronitrobenzene; 1-phenyl-2-(tetrahydropyrimidin-2(1H)-ylidene)ethan-1-one With potassium carbonate In 1,4-dioxane at 80℃; for 3h;
Stage #2: With caesium carbonate In 1,4-dioxane for 3h; Reflux;
93%
2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

2-amino-3,4-difluoronitro-benzene
211693-73-1

2-amino-3,4-difluoronitro-benzene

Conditions
ConditionsYield
With ammonium hydroxide In ethanol at 20℃; for 8h;91.2%
With ammonia In methanol at 70℃; for 1.5h; Microwave irradiation;73%
With ammonia In methanol at 70℃; for 1.5h; Microwave irradiation;35.6%
2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

(2R)-1-(benzyloxy)propan-2-ol
89401-28-5

(2R)-1-(benzyloxy)propan-2-ol

(R)-2-(1-benzyloxyisopropoxy)-3,4-difluoronitrobenzene

(R)-2-(1-benzyloxyisopropoxy)-3,4-difluoronitrobenzene

Conditions
ConditionsYield
With potassium hydroxide; potassium carbonate In water; toluene91%
2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

ethyl acetoacetate
141-97-9

ethyl acetoacetate

1-(2,3-difluoro-6-nitrophenyl)propan-2-one
121247-16-3

1-(2,3-difluoro-6-nitrophenyl)propan-2-one

Conditions
ConditionsYield
With hydrogenchloride; acetic acid In tetrahydrofuran; water90%
Stage #1: ethyl acetoacetate With potassium tert-butylate In tetrahydrofuran at 11 - 25℃; for 1h;
Stage #2: 2,3,4-trifluoronitrobenzene In tetrahydrofuran at 10 - 21℃; for 3.08333h;
Stage #3: With sulfuric acid In acetic acid at 70℃; for 3h; Heating / reflux;
82%
With acetic acid In tetrahydrofuran; hydrogenchloride72%
With acetic acid In tetrahydrofuran; hydrogenchloride72%
With sodium hydride Yield given. Multistep reaction;
2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

3-chloro-5-[(2,3-difluoro-6-nitrophenyl)oxy]benzonitrile
770719-09-0

3-chloro-5-[(2,3-difluoro-6-nitrophenyl)oxy]benzonitrile

Conditions
ConditionsYield
Stage #1: 3-chloro-5-hydroxybenzonitrile With sodium t-butanolate In tetrahydrofuran at 0℃; for 0.25h;
Stage #2: 2,3,4-trifluoronitrobenzene In tetrahydrofuran at 0℃; for 3.5h;
89%
Stage #1: 3-bromo-5-chlorophenol With sodium t-butanolate In tetrahydrofuran at 0℃; for 1h;
Stage #2: 2,3,4-trifluoronitrobenzene In tetrahydrofuran at 0℃;
Stage #3: With hydrogenchloride In tetrahydrofuran; water for 1h;
82%
Stage #1: 3-chloro-5-hydroxybenzonitrile With sodium t-butanolate In tetrahydrofuran at 0℃; for 1h;
Stage #2: 2,3,4-trifluoronitrobenzene In tetrahydrofuran at 0℃;
82%
Stage #1: 3-chloro-5-hydroxybenzonitrile With potassium tert-butylate In tetrahydrofuran at 0℃; for 0.333333h;
Stage #2: 2,3,4-trifluoronitrobenzene In tetrahydrofuran at 20℃; for 2h;
3-chloro-5-hydroxybenzonitrile
473923-97-6

3-chloro-5-hydroxybenzonitrile

2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

3-chloro-5-[(2,3-difluoro-6-nitrophenyl)oxy]benzonitrile
770719-09-0

3-chloro-5-[(2,3-difluoro-6-nitrophenyl)oxy]benzonitrile

Conditions
ConditionsYield
Stage #1: 3-chloro-5-hydroxybenzonitrile With sodium t-butanolate In tetrahydrofuran at 0℃;
Stage #2: 2,3,4-trifluoronitrobenzene In tetrahydrofuran at 0 - 20℃;
89%
With sodium t-butanolate In tetrahydrofuran at 0℃; for 1h;82%
Stage #1: 3-chloro-5-hydroxybenzonitrile With sodium t-butanolate In tetrahydrofuran at 0℃; for 1h;
Stage #2: 2,3,4-trifluoronitrobenzene In tetrahydrofuran at 0℃;
Stage #3: With hydrogenchloride; water In tetrahydrofuran for 1h;
82%
methanol
67-56-1

methanol

2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

2-fluoro-1,3-dimethoxy-4-nitrobenzene
155020-44-3

2-fluoro-1,3-dimethoxy-4-nitrobenzene

Conditions
ConditionsYield
With sodium methylate for 48h; Reflux;89%
2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

ethyl acetoacetate
141-97-9

ethyl acetoacetate

A

1,2-difluoro-3-(2,2-dimethoxypropyl)-4-nitrobenzene
288385-96-6

1,2-difluoro-3-(2,2-dimethoxypropyl)-4-nitrobenzene

B

1-(2,3-difluoro-6-nitrophenyl)propan-2-one
121247-16-3

1-(2,3-difluoro-6-nitrophenyl)propan-2-one

Conditions
ConditionsYield
With acetic acid In tetrahydrofuran; hydrogenchlorideA 88%
B 72%
2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

3,4-difluoro-2-(3,5-bis-tert-butylcarbamoyl-phenoxy)nitrobenzene
866959-42-4

3,4-difluoro-2-(3,5-bis-tert-butylcarbamoyl-phenoxy)nitrobenzene

Conditions
ConditionsYield
Stage #1: N,N'-di-tert-butyl-5-hydroxy-isophthalamide With potassium tert-butylate In tetrahydrofuran at 0℃; for 0.5h;
Stage #2: 2,3,4-trifluoronitrobenzene In tetrahydrofuran at -35 - 30℃; for 21h;
88%
2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

1-(4-methoxyphenyl)-2-(tetrahydropyrimidin-2(1H)-ylidene)ethan-1-one
107165-84-4

1-(4-methoxyphenyl)-2-(tetrahydropyrimidin-2(1H)-ylidene)ethan-1-one

6-fluoro-10-(4-methoxybenzoyl)-9-nitro-1,2,3,4-tetrahydropyrimido[1,2-a]indole

6-fluoro-10-(4-methoxybenzoyl)-9-nitro-1,2,3,4-tetrahydropyrimido[1,2-a]indole

Conditions
ConditionsYield
Stage #1: 2,3,4-trifluoronitrobenzene; 1-(4-methoxyphenyl)-2-(tetrahydropyrimidin-2(1H)-ylidene)ethan-1-one With triethylamine In 1,4-dioxane at 60℃; for 5h;
Stage #2: With caesium carbonate In 1,4-dioxane for 3h; Reflux;
87%
2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

2,3-difluoro-6-nitrophenol
82419-26-9

2,3-difluoro-6-nitrophenol

Conditions
ConditionsYield
With potassium hydroxide; sulfuric acid In water86%
With potassium hydroxide In water; dimethyl sulfoxide at 18 - 20℃; for 2h;29%
With potassium hydroxide In water; dimethyl sulfoxide
With potassium hydroxide In dimethyl sulfoxide at 15 - 17℃; for 3h;38.8g
1-methyl-piperazine
109-01-3

1-methyl-piperazine

2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

1-(2,3-difluoro-4-nitrophenyl)-4-methylpiperazine

1-(2,3-difluoro-4-nitrophenyl)-4-methylpiperazine

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 0℃; for 1h;86%
7-Indolol
2380-84-9

7-Indolol

2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

C14H8F2N2O3
770718-79-1

C14H8F2N2O3

Conditions
ConditionsYield
With sodium t-butanolate In tetrahydrofuran at 0℃; for 2h;84%
Stage #1: 7-Indolol With sodium t-butanolate In tetrahydrofuran at 0℃; for 0.166667h;
Stage #2: 2,3,4-trifluoronitrobenzene In tetrahydrofuran
84%
methanolic ammonia

methanolic ammonia

2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

2-amino-3,4-difluoronitro-benzene
211693-73-1

2-amino-3,4-difluoronitro-benzene

Conditions
ConditionsYield
In ethyl acetate84%
2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

(R)-(-)-2-(1-ethoxyethoxy)-1-propanol
184110-41-6

(R)-(-)-2-(1-ethoxyethoxy)-1-propanol

(R)-2-[2-(1-ethoxyethoxy)propoxy]-3,4-difluoronitrobenzene

(R)-2-[2-(1-ethoxyethoxy)propoxy]-3,4-difluoronitrobenzene

Conditions
ConditionsYield
In tetrahydrofuran; diethyl ether; water82%
With potassium hydroxide; potassium carbonate In water; toluene6.7%
3-(difluoromethyl)-5-hydroxybenzonitrile
874974-85-3

3-(difluoromethyl)-5-hydroxybenzonitrile

2,3,4-trifluoronitrobenzene
771-69-7

2,3,4-trifluoronitrobenzene

3-difluoromethyl-5-(2,3-difluoro-6-nitro-phenoxy)-benzonitrile
1068603-76-8

3-difluoromethyl-5-(2,3-difluoro-6-nitro-phenoxy)-benzonitrile

Conditions
ConditionsYield
Stage #1: 3-(difluoromethyl)-5-hydroxybenzonitrile; 2,3,4-trifluoronitrobenzene With potassium carbonate In tetrahydrofuran at 0℃;
Stage #2: With acetic acid In tetrahydrofuran at 0 - 5℃; Product distribution / selectivity;
80%

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