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hangzhou verychem science and technology co.ltd

Product name: 2,4,5-Trichloropyrimidine Cas No:5750-76-5 Assay: 99%min Hangzhou Verychem Science And Technology Co. Ltd. was set up in year 2004, it’s a young but fast growing company. In the t

2,4,5-Trichloropyrimidine

Cas:5750-76-5

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Appearance:liquid Storage:Inert atmosphere,Store in freezer, under -20°C Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

2,4,5-Trichloropyrimidine cas no. 5750-76-5 98%

Cas:5750-76-5

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

2,4,5-Trichloropyrimidine

Cas:5750-76-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2,5,6-Trichloropyrimidine supplier in China

Cas:5750-76-5

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

2,4,5-Trichloropyrimidine

Cas:5750-76-5

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price OLED 99% 5750-76-5 2, 4, 5 -Trichloropyrimidine Manufacturer

Cas:5750-76-5

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

2,4,5-Trichloropyrimidine

Cas:5750-76-5

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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ANQING CHICO PHARMACEUTICAL CO.,LTD.

High quality. Factory supply. In stock. Best price.1.Quick response within 24 hours;2.Best quality in your requirement;?3.We pay more attention on delivery time, and usually ship on time;4.Under the premise of safety and effectiveness, we can produce

2,4,5-Trichloropyrimidine

Cas:5750-76-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2,4,5-Trichloropyrimidine

Cas:5750-76-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Leader Biochemical Group

About Product Technical Details MPC Basic information Product Name: MPC Synonyms: methyl propyl carbonate;MPC;Carbonic acid, methyl propyl ester;butan-2-ylcarbonate;Methyl propyl carbonate

China Largest factory Manufacturer Supply 2,4,5-Trichloropyrimidine CAS 5750-76-5

Cas:5750-76-5

Min.Order:1 Kilogram

FOB Price: $1.0 / 3.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

2,4,5-Trichloropyrimidine

Cas:5750-76-5

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

high quality 2,4,5-Trichloropyrimidine

Cas:5750-76-5

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

GMP Manufacturer CAS 5750-76-5 with high-quality service

Cas:5750-76-5

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product name 2,4,5-Trichloropyrimidine CAS NO. 5750-76-5 Synonyms 2,4,5-Trichloropyrimidine Category Pharmaceutical Intermediates, organic b

2,4,5-Trichloropyrimidine

Cas:5750-76-5

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry plac

2,4,5-Trichloropyrimidine CAS 5750-76-5

Cas:5750-76-5

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2,4,5-Trichloropyrimidine 5750-76-5

Cas:5750-76-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

2,4,5-Trichloropyrimidine

Cas:5750-76-5

Min.Order:1 Kilogram

FOB Price: $185.0 / 200.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

2,4,5-Trichloropyrimidine CAS:5750-76-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

2,4,5-Trichloropyrimidine CAS:5750-76-5

Cas:5750-76-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2,4,5-Trichloropyrimidine

Cas:5750-76-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2,5,6-Trichloropyrimidine

Cas:5750-76-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

CAS 5750-76-5 2,4,5-Trichloropyrimidine

Cas:5750-76-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2,4,5-Trichloro-pyriMidine

Cas:5750-76-5

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2,4,5-Trichloropyrimidine

Cas:5750-76-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

2,4,5-Trichloropyrimidine

Cas:5750-76-5

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2,4,5-Trichloropyrimidine

Cas:5750-76-5

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

cas:5750-76-5

Cas:5750-76-5

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 2,4,5-Trichloropyrimidine CAS No.:5750-76-5 Molecule Formula:C4HCl3N2 Molecule Weight:183.42 Purity: 98.0% Package: 200kg/drum Description:Light yellow to colorless liquid Manufacture Standards:Enterprise Standard

High Quality 2,4,5-Trichloropyrimidine

Cas:5750-76-5

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

2,4,5-Trichloropyrimidine

Cas:5750-76-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

2,4,5-Trichloropyrimidine Chemical Properties Boiling point 84°C 1mm density 1.6001 g/mL at 25 °C (lit.) refractive index n20/D 1.574(lit.) Fp >230 °F pka -4.26±0.29(Predicted) Water Solubility Not miscibl

2,4,5-Trichloropyrimidine

Cas:5750-76-5

Min.Order:1 Gram

FOB Price: $66.0

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

2,4,5-Trichloro-pyriMidine

Cas:5750-76-5

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Synthetic route

5-chlorouracil
1820-81-1

5-chlorouracil

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

Conditions
ConditionsYield
With phosphorus pentachloride; trichlorophosphate Neat (no solvent); Heating / reflux;95%
With phosgene; Triphenylphosphine oxide In nitrobenzene at -5 - 125℃; for 0.833333h; Inert atmosphere;93%
With N,N-diethylaniline; trichlorophosphate at 110℃; for 24h;81%
2,4-dihydroxy-5-chloropyrimidine
1820-81-1

2,4-dihydroxy-5-chloropyrimidine

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

Conditions
ConditionsYield
With dmap; thionyl chloride; bis(trichloromethyl) carbonate for 10h; Reflux; Green chemistry;91%
With pyridine; trichlorophosphate at 160℃; for 2h; Autoclave; neat (no solvent);89%
2-cyanoethyl isocyanide dichloride

2-cyanoethyl isocyanide dichloride

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

Conditions
ConditionsYield
With hydrogenchloride In chloroform; chlorine
With hydrogenchloride; thionyl chloride In chlorine
disulfur dichloride
10025-67-9

disulfur dichloride

sulphur dichloride

sulphur dichloride

(2-cyanoethyl)-methyl-dithiocarbamic acid methyl ester

(2-cyanoethyl)-methyl-dithiocarbamic acid methyl ester

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

4-fluoro-N-methylaniline
459-59-6

4-fluoro-N-methylaniline

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

2,5-dichloro-N-(4-fluorophenyl)-N-methylpyrimidin-4-amine
1341200-86-9

2,5-dichloro-N-(4-fluorophenyl)-N-methylpyrimidin-4-amine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol for 12h; Reflux;100%
4-difluoromethoxyaniline
22236-10-8

4-difluoromethoxyaniline

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

2,5-dichloro-N-(4-(difluoromethoxy)phenyl)pyrimidin-4-amine
1341200-83-6

2,5-dichloro-N-(4-(difluoromethoxy)phenyl)pyrimidin-4-amine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol for 12h; Reflux;100%
4-fluoroboronic acid
1765-93-1

4-fluoroboronic acid

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

2,5-dichloro-4-(4-fluorophenyl)pyrimidine
1341200-89-2

2,5-dichloro-4-(4-fluorophenyl)pyrimidine

Conditions
ConditionsYield
With palladium diacetate; sodium carbonate; triphenylphosphine In tetrahydrofuran; water for 12h; Suzuki coupling; Reflux;100%
2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

4-fluoroaniline
371-40-4

4-fluoroaniline

2,5-dichloro-N-(4-fluorophenyl)pyrimidine-4-amine
280582-13-0

2,5-dichloro-N-(4-fluorophenyl)pyrimidine-4-amine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol for 12h; Reflux;100%
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃;85%
Stage #1: 2,4,5-trichloropyrimidine With tetra-(n-butyl)ammonium iodide In dimethyl sulfoxide at 20℃;
Stage #2: 4-fluoroaniline With triethylamine In dimethyl sulfoxide at 20℃; for 3h;
65%
With sodium carbonate In ethanol at 20℃; for 16h;57%
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃;57%
5-aminohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester

5-aminohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

tert-butyl 5-((2,5-dichloropyrimidin-4-yl)amino)hexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate

tert-butyl 5-((2,5-dichloropyrimidin-4-yl)amino)hexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate

Conditions
ConditionsYield
With triethylamine In ethanol at 20℃;100%
With triethylamine In ethanol at 20℃;100%
With triethylamine In ethanol at 20℃;100%
(S)-10-amino-2-cyclopropyl-3,3-difluoro-7-methyl-1,2,3,4-tetrahydro-[1,4]oxazepino[2,3-c]quinolin-6(7H)-one

(S)-10-amino-2-cyclopropyl-3,3-difluoro-7-methyl-1,2,3,4-tetrahydro-[1,4]oxazepino[2,3-c]quinolin-6(7H)-one

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

(S)-2-cyclopropyl-10-((2,5-dichloropyrimidin-4-yl)amino)-3,3-difluoro-7-methyl-1,2,3,4-tetrahydro-[1,4]oxazepino[2,3-c]quinolin-6(7H)-one

(S)-2-cyclopropyl-10-((2,5-dichloropyrimidin-4-yl)amino)-3,3-difluoro-7-methyl-1,2,3,4-tetrahydro-[1,4]oxazepino[2,3-c]quinolin-6(7H)-one

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In 1-methyl-pyrrolidin-2-one at 140℃; for 1h; Inert atmosphere; Microwave irradiation; Sealed tube;100%
With N-ethyl-N,N-diisopropylamine In 1-methyl-pyrrolidin-2-one at 140℃; for 1h; Inert atmosphere; Microwave irradiation;88%
2,2,2-trifluoroethanol
75-89-8

2,2,2-trifluoroethanol

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

2,5-dichloro-4-(2,2,2-trifluoroethoxy)pyrimidine

2,5-dichloro-4-(2,2,2-trifluoroethoxy)pyrimidine

Conditions
ConditionsYield
With potassium carbonate at 20℃; for 2h;100%
2-fluoro-6-nitroaniline
17809-36-8

2-fluoro-6-nitroaniline

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

2,5-dichloro-N-(2-fluoro-6-nitrophenyl)pyrimidin-4-amine

2,5-dichloro-N-(2-fluoro-6-nitrophenyl)pyrimidin-4-amine

Conditions
ConditionsYield
Stage #1: 2-fluoro-6-nitroaniline With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.5h;
Stage #2: 2,4,5-trichloropyrimidine In N,N-dimethyl-formamide; mineral oil at 0℃; for 2h;
100%
2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

aniline
62-53-3

aniline

4-Anilino-2,5-dichloropyrimidine
280581-45-5

4-Anilino-2,5-dichloropyrimidine

Conditions
ConditionsYield
With potassium phosphate; TPGS-750-M In water at 20℃; for 24h; Inert atmosphere;99%
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol for 12h; Reflux;92%
Stage #1: 2,4,5-trichloropyrimidine With tetra-(n-butyl)ammonium iodide In dimethyl sulfoxide at 20℃;
Stage #2: aniline With triethylamine In dimethyl sulfoxide at 20℃; for 3h;
89%
2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

tert-butyl ((1r,4r)-4-(aminomethyl)cyclohexyl)carbamate
177583-27-6

tert-butyl ((1r,4r)-4-(aminomethyl)cyclohexyl)carbamate

{4-[(2,5-dichloro-pyrimidin-4-ylamino)-methyl]-cyclohexyl}-carbamic acid tert-butyl ester
874822-31-8

{4-[(2,5-dichloro-pyrimidin-4-ylamino)-methyl]-cyclohexyl}-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In ethanol at 40℃; for 1h;99%
2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

4-chloro-aniline
106-47-8

4-chloro-aniline

2,5-dichloro-N-(4-chlorophenyl)pyrimidin-4-amine
1341200-80-3

2,5-dichloro-N-(4-chlorophenyl)pyrimidin-4-amine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol for 12h; Reflux;99%
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 16h;61%
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃;61%
(R)-1-(4-methoxyphenyl)ethylamine
6298-96-0, 22038-86-4, 35600-82-9, 41851-59-6

(R)-1-(4-methoxyphenyl)ethylamine

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

(S)-2,5-dichloro-N-(1-(4-methoxyphenyl)ethyl)pyrimidin-4-amine

(S)-2,5-dichloro-N-(1-(4-methoxyphenyl)ethyl)pyrimidin-4-amine

Conditions
ConditionsYield
With potassium phosphate; TPGS-750-M In water at 20℃; for 20h; Inert atmosphere;99%
2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

phenol
108-95-2

phenol

2,5-dichloro-4-phenoxypyrimidine

2,5-dichloro-4-phenoxypyrimidine

Conditions
ConditionsYield
With potassium carbonate In acetone at 20℃; for 6h;99%
Stage #1: 2,4,5-trichloropyrimidine With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.25h; Inert atmosphere;
Stage #2: phenol In N,N-dimethyl-formamide at 20℃; for 3h; Inert atmosphere;
92%
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 4h;
3-((5-methyl-4-nitro-1H-pyrazol-3-yl)oxy)propan-1-amine hydrochloride

3-((5-methyl-4-nitro-1H-pyrazol-3-yl)oxy)propan-1-amine hydrochloride

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

2,5-dichloro-N-(3-((5-methyl-4-nitro-1H-pyrazol-3-yl)oxy)propyl)pyrimidin-4-amine

2,5-dichloro-N-(3-((5-methyl-4-nitro-1H-pyrazol-3-yl)oxy)propyl)pyrimidin-4-amine

Conditions
ConditionsYield
Stage #1: 3-((5-methyl-4-nitro-1H-pyrazol-3-yl)oxy)propan-1-amine hydrochloride With N-ethyl-N,N-diisopropylamine In isopropyl alcohol at 0℃; for 0.166667h; Inert atmosphere;
Stage #2: 2,4,5-trichloropyrimidine In isopropyl alcohol at 0 - 20℃; Inert atmosphere;
99%
sodium thiomethanolate

sodium thiomethanolate

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

2,5-dichloro-4-(methylthio)pyrimidine
1245830-98-1

2,5-dichloro-4-(methylthio)pyrimidine

Conditions
ConditionsYield
In tetrahydrofuran; water at 0 - 20℃; for 4h;99%
4-fluoro-2-{[(oxan-2-yl)oxy]methyl}-1-(propan-2-yl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole

4-fluoro-2-{[(oxan-2-yl)oxy]methyl}-1-(propan-2-yl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

6-(2,5-dichloropyrimidin-4-yl)-4-fluoro-2-{[(oxan-2-yl)oxy]methyl}-1-(propan-2-yl)-1H-benzimidazole

6-(2,5-dichloropyrimidin-4-yl)-4-fluoro-2-{[(oxan-2-yl)oxy]methyl}-1-(propan-2-yl)-1H-benzimidazole

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In 1,4-dioxane; water at 90℃; for 16h; Inert atmosphere;99%
cis-2-(3a,6a-dimethyl-1-oxohexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)acetamide

cis-2-(3a,6a-dimethyl-1-oxohexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)acetamide

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

cis-2-(5-(2,5-dichloropyrimidin-4-yl)-3a,6a-dimethyl-1-oxohexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)acetamide

cis-2-(5-(2,5-dichloropyrimidin-4-yl)-3a,6a-dimethyl-1-oxohexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)acetamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In acetonitrile at 50℃; for 12h; Inert atmosphere;99%
2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

methylamine
74-89-5

methylamine

2-chloro-5-chloro-N-methylpyrimidin-4-amine
940927-35-5

2-chloro-5-chloro-N-methylpyrimidin-4-amine

Conditions
ConditionsYield
In tetrahydrofuran at 0 - 20℃; regioselective reaction;98%
In tetrahydrofuran at 0 - 20℃; for 6h; regioselective reaction;85%
In ethanol at 0℃;83%
2-(2-ethynylphenyl)propanamide
1566543-62-1

2-(2-ethynylphenyl)propanamide

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

2-(2-((2,5-dichloropyrimidin-4-yl)ethynyl)phenyl)propanamide
1566543-95-0

2-(2-((2,5-dichloropyrimidin-4-yl)ethynyl)phenyl)propanamide

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine In 1,4-dioxane at 60℃; for 2.5h; Inert atmosphere;98%
2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

naphthalen-2-ylamine
91-59-8

naphthalen-2-ylamine

2,5-dichloro-N-(naphthalene-2-yl)pyrimidin-4-amine

2,5-dichloro-N-(naphthalene-2-yl)pyrimidin-4-amine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol for 2h; Reflux;98%
With sodium carbonate In ethanol at 20℃; regioselective reaction;88%
With sodium carbonate In ethanol at 20℃;88%
With sodium carbonate In ethanol88%
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol for 3h; Heating;79.6%
5-(1,1-dioxothiomorpholin-4-yl)pentylamine

5-(1,1-dioxothiomorpholin-4-yl)pentylamine

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

N-(2,5-dichloropyrimidin-4-yl)-5-(1,1-dioxothiomorpholin-4-yl)pentylamine

N-(2,5-dichloropyrimidin-4-yl)-5-(1,1-dioxothiomorpholin-4-yl)pentylamine

Conditions
ConditionsYield
With triethylamine In ethanol at 70℃; for 4h;98%
4-fluoro-1-isopropyl-2-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)-1H-benzo[d]imidazole
1231930-37-2

4-fluoro-1-isopropyl-2-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)-1H-benzo[d]imidazole

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

6-(2,5-dichloropyrimidin-4-yl)-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

6-(2,5-dichloropyrimidin-4-yl)-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In 1,4-dioxane; water at 90℃; for 16h; Inert atmosphere;98%
With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate In water; N,N-dimethyl-formamide at 60℃; for 2h; Inert atmosphere;31%
4-(4-amino-5-isopropoxy-2-methylphenyl)-piperidine-1-carboxylic acid tert-butyl ester
1032903-63-1

4-(4-amino-5-isopropoxy-2-methylphenyl)-piperidine-1-carboxylic acid tert-butyl ester

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

4-(4-((4,5-dichloropyrimidin-2-yl)amino)-5-isopropoxy-2-methylphenyl)piperidine-1-carboxylic acid tert-butyl ester

4-(4-((4,5-dichloropyrimidin-2-yl)amino)-5-isopropoxy-2-methylphenyl)piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol at 80℃; for 24h; Reagent/catalyst; Temperature; Solvent; Inert atmosphere;97.9%
2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

(R)-2-amino-2-(4-fluorophenyl)ethanol
174770-74-2

(R)-2-amino-2-(4-fluorophenyl)ethanol

(2R)-2-[(2,5-dichloropyrimidin-4-yl)amino]-2-(4-fluorophenyl)ethanol

(2R)-2-[(2,5-dichloropyrimidin-4-yl)amino]-2-(4-fluorophenyl)ethanol

Conditions
ConditionsYield
With triethylamine In ethanol at 20℃; for 12h;97%
5-methoxy-1H-pyrazol-3-amine
41307-23-7

5-methoxy-1H-pyrazol-3-amine

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

2,5-dichloro-N-(5-methoxy-1H-pyrazol-3-yl)pyrimidin-4-amine
915720-77-3

2,5-dichloro-N-(5-methoxy-1H-pyrazol-3-yl)pyrimidin-4-amine

Conditions
ConditionsYield
With triethylamine In ethanol at 18 - 25℃; for 12h; regioselective reaction;97%
With triethylamine In ethanol at 18 - 25℃; for 12h;
With triethylamine In ethanol at 20℃; for 12h;
2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

Cyclopropylamine
765-30-0

Cyclopropylamine

2,5-dichloro-N-cyclopropylpyrimidin-4-amine
1050602-55-5

2,5-dichloro-N-cyclopropylpyrimidin-4-amine

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at -10 - 20℃;97%
In ethanol at 0℃;63%
With N-ethyl-N,N-diisopropylamine for 12h; Reflux;45%
morpholine
110-91-8

morpholine

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

4-(2,5-dichloropyrimidin-4-yl)morpholine
1215126-57-0

4-(2,5-dichloropyrimidin-4-yl)morpholine

Conditions
ConditionsYield
With potassium phosphate monohydrate; C64H118O20 In water at 45℃; for 3h; Reagent/catalyst;97%
With potassium phosphate; TPGS-750-M In water at 20℃; for 20h; Inert atmosphere;86%
In ethanol at 0℃; for 3h;70%
With triethylamine In tetrahydrofuran at 25℃; for 1h; Inert atmosphere;
2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

3,5-Dimethoxyaniline
10272-07-8

3,5-Dimethoxyaniline

2,5-dichloro-N4-(3,5-dimethoxyphenyl)pyrimidin-4-amine

2,5-dichloro-N4-(3,5-dimethoxyphenyl)pyrimidin-4-amine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol for 2h; Reflux;97%
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol for 0.166667h; Reflux;85%
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol for 0.166667h; Reflux;85%
2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

3,4,5-Trimethoxyaniline
24313-88-0

3,4,5-Trimethoxyaniline

2,5-dichloro-N4-(3,4,5-trimethoxyphenyl)pyrimidin-4-amine

2,5-dichloro-N4-(3,4,5-trimethoxyphenyl)pyrimidin-4-amine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol for 14h; Reflux;97%
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol for 14h; Reflux;97%
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol for 2h; Reflux;32%
3-fluoro-4-methoxyaniline
366-99-4

3-fluoro-4-methoxyaniline

2,4,5-trichloropyrimidine
5750-76-5

2,4,5-trichloropyrimidine

2,5-dichloro-N-(3-fluoro-4-methoxyphenyl)pyrimidin-4-amine

2,5-dichloro-N-(3-fluoro-4-methoxyphenyl)pyrimidin-4-amine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol for 2h; Reflux;97%

Raw Materials

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