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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine chemicals, ph

Cyclopropyl isocyanide

Cas:58644-53-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

Cyclopropyl isocyanide CAS:58644-53-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic in

Cyclopropyl isocyanide CAS:58644-53-4

Cas:58644-53-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Cyclopropane, isocyano-

Cas:58644-53-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Cyclopropane, isocyano-

Cas:58644-53-4

Min.Order:0

Negotiable

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Cyclopropane isocarbonitrile

Cas:58644-53-4

Min.Order:0 Metric Ton

Negotiable

Type:Other

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Cyclopropane, isocyano-

Cas:58644-53-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Cyclopropyl isocyanide

Cas:58644-53-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white crystalline powder Storage:Sealed in a cool ,dry and microtherm place , avoid light . Package:100g/bottle,1kg/bottle,25kg/drum or as per your request Application:It is an impo

58644-53-4 supplier in China

Cas:58644-53-4

Min.Order:100 Gram

Negotiable

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

Cyclopropyl isocyanide

Cas:58644-53-4

Min.Order:0

Negotiable

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

Cyclopropane, isocyano-

Cas:58644-53-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

Cyclopropyl isocyanide

Cas:58644-53-4

Min.Order:0

Negotiable

Type:Manufacturers

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Cyclopropane, isocyano-

Cas:58644-53-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou Ocean Chemical Co., Ltd.

★.Best quality according to requirement ★.Competitive price in China market ★.Mature Technical support ★.Professional logistic support

Cyclopropylisonitrile

Cas:58644-53-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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DB BIOTECH CO., LTD

best seller Application:API

Cyclopropyl isocyanide

Cas:58644-53-4

Min.Order:0

Negotiable

Type:Trading Company

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BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:white solid Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as primary an

Cyclopropyl isoCyanide

Cas:58644-53-4

Min.Order:0

Negotiable

Type:Trading Company

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Hangzhou Fandachem Co.,Ltd

Cyclopropyl isocyanideAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:pharmaceutical intermediate Transportation:by air, by sea, by express

Cyclopropyl isocyanide

Cas:58644-53-4

Min.Order:0

Negotiable

Type:Other

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Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Cyclopropyl isocyanide

Cas:58644-53-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

Cyclopropyl isocyanide

Cas:58644-53-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Pharm intermediate

Cyclopropyl isocyanide

Cas:58644-53-4

Min.Order:0

Negotiable

Type:Trading Company

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Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

58644-53-4

Cas:58644-53-4

Min.Order:0

Negotiable

Type:Trading Company

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Hebei Muhuang Technology Co., Ltd

best seller Application:API

Cyclopropyl isocyanide

Cas:58644-53-4

Min.Order:0

Negotiable

Type:Trading Company

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ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Cyclopropyl isocyanide

Cas:58644-53-4

Min.Order:0

Negotiable

Type:Trading Company

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Shaanxi Mingqi Chemical Co., Ltd

Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers.1) Standard:BP/USP/EP/Enterprise standard2) All Purity≥99%3) We are manufacturer and can provide high quality products with factory pric

Manufacturer Supply Top quality Cyclopropyl isocyanide

Cas:58644-53-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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HuBei Ipure Biotech CO.,ltd

HuBei ipure is a diversified product production and operation enterprise, with API, pharma intermediates, and other fine chemicals as well as R&D and pigments development and sales as one of the large enterprises, with more than 130 acres of plant

Cyclopropane, isocyano-

Cas:58644-53-4

Min.Order:1 Gram

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.

Reply quotation within 2 hours.Guarantee the time of delivery. Update the progress of customization Weekly.High purity& High product customization success rate.Inquiries for other compounds are acceptable. Storage:refrigeration Package:1g,5g,10g,100g

Cyclopropyl isocyanide

Cas:58644-53-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai united Scientific Co.,Ltd.

United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat

Cyclopropane, isocyano-

Cas:58644-53-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chungking Joyinchem Co., Ltd.

Joyinchem have been committed to chemical supply for several years and have built good cooperation records with multinational chemical corporations and importers from all over the world. Our services include:-Spot goods-Contract manufacturing-Custom

Cyclopropane, isocyano-

Cas:58644-53-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Finetech Industry Limited

FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the Cyclopropylisonitrile, CAS:58644-53-4 with the most competitive price and the best qu

Cyclopropylisonitrile

Cas:58644-53-4

Min.Order:0

Negotiable

Type:Trading Company

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Nanjing Raymon Biotech Co., Ltd.

Cyclopropane, isocyano- Storage:keep in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical research/pharma intermediate Transportation:By Sea,by Air,By courier like DHL or Fedx. Port:Shanghai/Shenzhen

Cyclopropane, isocyano-

Cas:58644-53-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Changzhou Run-chem Biological Co.,ltd

Cyclopropyl isocyanide 58644-53-4 98% Storage:dry and ventilated place Package:suitable for shipping Application:Cyclopropyl isocyanide 58644-53-4 98% Transportation:air shipping Port:shanghai

Cyclopropyl isocyanide 58644-53-4 98%

Cas:58644-53-4

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

inquiry

Synthetic route

N-cyclopropylformamide
58644-54-5

N-cyclopropylformamide

cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

Conditions
ConditionsYield
With tributyl-amine; p-toluenesulfonyl chloride
With p-toluenesulfonyl chloride at 100℃;
With isocyanate de chlorosulfonyle; triethylamine In methanol; dichloromethane; toluene at 0 - 40℃; for 5.5h;
With triethylamine; trichlorophosphate In dichloromethane for 0.0666667h; Cooling with ice; Green chemistry;
chloroform
67-66-3

chloroform

Cyclopropylamine
765-30-0

Cyclopropylamine

cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

Conditions
ConditionsYield
With N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide In dichloromethane; water at 20℃; for 12h;
cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

(2S)-2-(tert-butoxycarbonyl)aminobutyraldehyde
153371-25-6

(2S)-2-(tert-butoxycarbonyl)aminobutyraldehyde

(2S,3S)-3-(tert-butoxycarbonylamino)-1-(cyclopropylamino)-1-oxopentan-2-yl acetate
1439404-21-3

(2S,3S)-3-(tert-butoxycarbonylamino)-1-(cyclopropylamino)-1-oxopentan-2-yl acetate

Conditions
ConditionsYield
With acetic acid In dichloromethane Inert atmosphere;100%
With acetic acid In dichloromethane at 20℃; Inert atmosphere;100%
{1-[2-(1-formyl-3-methyl-cyclobutylcarbamoyl)-6,6-dimethyl-3-aza-bicyclo[3.1.0]hexane-3-carbonyl]-2,2-dimethyl-propyl}-carbamic acid tert-butyl ester
1101869-53-7

{1-[2-(1-formyl-3-methyl-cyclobutylcarbamoyl)-6,6-dimethyl-3-aza-bicyclo[3.1.0]hexane-3-carbonyl]-2,2-dimethyl-propyl}-carbamic acid tert-butyl ester

cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

acetic acid
64-19-7

acetic acid

acetic acid (1-{[3-(2-tert-butoxycarbonylamino-3,3-dimethyl-butyryl)-6,6-dimethyl-3-aza-bicyclo[3.1.0]hexane-2-carbonyl]-amino}-3-methyl-cyclobutyl)-cyclopropylcarbamoyl-methyl ester
1101869-54-8

acetic acid (1-{[3-(2-tert-butoxycarbonylamino-3,3-dimethyl-butyryl)-6,6-dimethyl-3-aza-bicyclo[3.1.0]hexane-2-carbonyl]-amino}-3-methyl-cyclobutyl)-cyclopropylcarbamoyl-methyl ester

Conditions
ConditionsYield
94%
cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

cyclopropropanecarbonitrile
5500-21-0

cyclopropropanecarbonitrile

Conditions
ConditionsYield
at 520 - 550℃; under 0.01 Torr;92%
With 1,1-Diphenylethylene In various solvent(s) at 210℃; Rate constant; Thermodynamic data; ΔG(excit.) <250 deg C>; ΔH(excit.), ΔS(excit.);98 % Chromat.
C26H41F2N3O5
1231183-20-2

C26H41F2N3O5

cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

acetic acid
64-19-7

acetic acid

C32H50F2N4O7
1231182-76-5

C32H50F2N4O7

Conditions
ConditionsYield
In ethyl acetate at 20℃; Passerini reaction; Cooling with ice;90%
3-pyridinecarboxaldehyde
500-22-1

3-pyridinecarboxaldehyde

2-furanoic acid
88-14-2

2-furanoic acid

cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

4-Aminobiphenyl
92-67-1

4-Aminobiphenyl

2-(N-{[1,1′-biphenyl]-4-yl}-1-(furan-2-yl)formamido)-N-cyclopropyl-2-(pyridin-3-yl)acetamide

2-(N-{[1,1′-biphenyl]-4-yl}-1-(furan-2-yl)formamido)-N-cyclopropyl-2-(pyridin-3-yl)acetamide

Conditions
ConditionsYield
Stage #1: 3-pyridinecarboxaldehyde; 4-phenylalanine In methanol at 20℃; for 0.5h; Ugi Condensation; Inert atmosphere;
Stage #2: 2-furanoic acid; cyclopropyl isocyanide In methanol at 20℃; Ugi Condensation; Inert atmosphere;
89%
2-iodobenzophenone
25187-00-2

2-iodobenzophenone

cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

2-benzoyl-N-cyclopropylbenzamide

2-benzoyl-N-cyclopropylbenzamide

Conditions
ConditionsYield
With 2,6-dimethylpyridine; copper(I) oxide In water at 80℃; for 1h; Sonication; Green chemistry;85%
cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

(1S,3aR,6aS)-2-((S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-hydroxypent-2-yl)octahydrocyclopenta[c]pyrrole-1-carboxamide

(1S,3aR,6aS)-2-((S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-hydroxypent-2-yl)octahydrocyclopenta[c]pyrrole-1-carboxamide

acetic acid
64-19-7

acetic acid

C38H57N7O7
1257874-86-4

C38H57N7O7

Conditions
ConditionsYield
Stage #1: (1S,3aR,6aS)-2-((S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-hydroxypent-2-yl)octahydrocyclopenta[c]pyrrole-1-carboxamide With sulfur trioxide pyridine complex; triethylamine In dichloromethane; dimethyl sulfoxide at -12 - -10℃;
Stage #2: cyclopropyl isocyanide; acetic acid In dichloromethane at 0 - 20℃; for 18h;
84%
cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

(R)-2,2,5,5-tetramethyl-[1,3]dioxane-4-carboxylic acid (3-oxopropyl)amide

(R)-2,2,5,5-tetramethyl-[1,3]dioxane-4-carboxylic acid (3-oxopropyl)amide

(R)-2,2,5,5-tetramethyl-[1,3]dioxane-4-carboxylic acid (3-cyclopropylcarbamoyl-3-hydroxypropyl)amide

(R)-2,2,5,5-tetramethyl-[1,3]dioxane-4-carboxylic acid (3-cyclopropylcarbamoyl-3-hydroxypropyl)amide

Conditions
ConditionsYield
Stage #1: cyclopropyl isocyanide; (R)-2,2,5,5-tetramethyl-[1,3]dioxane-4-carboxylic acid (3-oxopropyl)amide With chloroacetic acid In dichloromethane at 0 - 20℃; for 12h;
Stage #2: With water; potassium carbonate In methanol at 20℃; for 5h;
81%
chloroform
67-66-3

chloroform

cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

acetone
67-64-1

acetone

3-(cyclopropylamino)-2,2-dimethyl-3-oxopropanoic acid

3-(cyclopropylamino)-2,2-dimethyl-3-oxopropanoic acid

Conditions
ConditionsYield
With sodium hydroxide at 0 - 20℃; Bargellini Reaction;80%
3-pyridinecarboxaldehyde
500-22-1

3-pyridinecarboxaldehyde

2-furanoic acid
88-14-2

2-furanoic acid

4-tert-Butylaniline
769-92-6

4-tert-Butylaniline

cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

2-[N-(4-tert-butylphenyl)-1-(furan-2-yl)formamido]-N-cyclopropyl-2-(pyridin-3-yl)acetamide

2-[N-(4-tert-butylphenyl)-1-(furan-2-yl)formamido]-N-cyclopropyl-2-(pyridin-3-yl)acetamide

Conditions
ConditionsYield
Stage #1: 3-pyridinecarboxaldehyde; 4-tert-Butylaniline In methanol at 20℃; for 0.5h; Ugi Condensation; Inert atmosphere;
Stage #2: 2-furanoic acid; cyclopropyl isocyanide In methanol at 20℃; Ugi Condensation; Inert atmosphere;
80%
(S)-(9H-fluoren-9-yl)methyl 1-cyclobutyl-3-oxopropan-2-ylcarbamate
1035377-59-3

(S)-(9H-fluoren-9-yl)methyl 1-cyclobutyl-3-oxopropan-2-ylcarbamate

cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

acetic acid
64-19-7

acetic acid

(3S)-3-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-cyclobutyl-1-(cyclopropylamino)-1-oxobutan-2-yl acetate
1035377-60-6

(3S)-3-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-cyclobutyl-1-(cyclopropylamino)-1-oxobutan-2-yl acetate

Conditions
ConditionsYield
In dichloromethane at 0 - 20℃; for 16h;73%
1-phenylmethyl-4-piperidone
3612-20-2

1-phenylmethyl-4-piperidone

L-phenylalanine
63-91-2

L-phenylalanine

cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

(S)-2,9-dibenzyl-4-cyclopropyl-1,4,9-triazaspiro[5.5]undecane-3,5-dione

(S)-2,9-dibenzyl-4-cyclopropyl-1,4,9-triazaspiro[5.5]undecane-3,5-dione

Conditions
ConditionsYield
In 2,2,2-trifluoroethanol at 60℃; for 24h;71%
tert-butyl-N-{2-[N-(3′-oxopentyl)(2-nitrophenyl)sulfonamido]ethyl}carbamate
1489247-14-4

tert-butyl-N-{2-[N-(3′-oxopentyl)(2-nitrophenyl)sulfonamido]ethyl}carbamate

cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

trifluoroacetic acid
76-05-1

trifluoroacetic acid

N-cyclopropyl-5-ethyl-1-[(2-nitrophenyl)sulfonyl]-4-(trifluoroacetyl)-1,4-diazepane-5-carboxamide

N-cyclopropyl-5-ethyl-1-[(2-nitrophenyl)sulfonyl]-4-(trifluoroacetyl)-1,4-diazepane-5-carboxamide

Conditions
ConditionsYield
Stage #1: tert-butyl-N-{2-[N-(3′-oxopentyl)(2-nitrophenyl)sulfonamido]ethyl}carbamate; trifluoroacetic acid In dichloromethane at 20℃; Inert atmosphere;
Stage #2: cyclopropyl isocyanide In ethanol at 0℃; Inert atmosphere;
66%
tert-butyl-N-{2-[N-(3′-oxopentyl)(2-nitrophenyl)sulfonamido]ethyl}carbamate
1489247-14-4

tert-butyl-N-{2-[N-(3′-oxopentyl)(2-nitrophenyl)sulfonamido]ethyl}carbamate

cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

N-cyclopropyl-5-ethyl-1-[(2-nitrophenyl)sulfonyl]-4-(trifluoroacetyl)-1,4-diazepane-5-carboxamide

N-cyclopropyl-5-ethyl-1-[(2-nitrophenyl)sulfonyl]-4-(trifluoroacetyl)-1,4-diazepane-5-carboxamide

Conditions
ConditionsYield
Stage #1: tert-butyl-N-{2-[N-(3′-oxopentyl)(2-nitrophenyl)sulfonamido]ethyl}carbamate With trifluoroacetic acid at 20℃;
Stage #2: cyclopropyl isocyanide In ethanol at 0 - 20℃;
66%
(S)-N-(1-hydroxypentan-2-yl)formamide
1257874-84-2

(S)-N-(1-hydroxypentan-2-yl)formamide

cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

(S)-1-(cyclopropylamino)-3-formamido-1-oxohexan-2-yl acetate
1257874-85-3

(S)-1-(cyclopropylamino)-3-formamido-1-oxohexan-2-yl acetate

Conditions
ConditionsYield
Stage #1: (S)-N-(1-hydroxypentan-2-yl)formamide With Dess-Martin periodane In dichloromethane at 20℃; for 1h;
Stage #2: cyclopropyl isocyanide In dichloromethane for 48h;
60%
Stage #1: (S)-N-(1-hydroxypentan-2-yl)formamide With Dess-Martin periodane In dichloromethane at 20℃; for 48h; Dess-Martin oxidation;
Stage #2: cyclopropyl isocyanide With acetic acid In dichloromethane at 20℃; for 72h; Passerini reaction;
0.99 g
(S)-N-(1-hydroxypentan-2-yl)formamide
1257874-84-2

(S)-N-(1-hydroxypentan-2-yl)formamide

cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

Dess-Martin periodane
87413-09-0

Dess-Martin periodane

(S)-1-(cyclopropylamino)-3-formamido-1-oxohexan-2-yl acetate
1257874-85-3

(S)-1-(cyclopropylamino)-3-formamido-1-oxohexan-2-yl acetate

Conditions
ConditionsYield
Stage #1: (S)-N-(1-hydroxypentan-2-yl)formamide; Dess-Martin periodane In dichloromethane at 20℃; for 1h; Dess-Martin oxidation;
Stage #2: cyclopropyl isocyanide In dichloromethane for 48h; Passerini reaction; optical yield given as %de;
60%
3-pyridinecarboxaldehyde
500-22-1

3-pyridinecarboxaldehyde

N-(3-(trifluoromethyl)benzyl)cyclopropanamine
16065-24-0

N-(3-(trifluoromethyl)benzyl)cyclopropanamine

cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

N-((1-cyclopropyl-1H-tetrazol-5-yl)(pyridin-3-yl)methyl)-N-(3-(trifluoromethyl)benzyl)cyclopropanamine

N-((1-cyclopropyl-1H-tetrazol-5-yl)(pyridin-3-yl)methyl)-N-(3-(trifluoromethyl)benzyl)cyclopropanamine

Conditions
ConditionsYield
With trimethylsilylazide In methanol at 20℃; Ugi Condensation; Inert atmosphere;59%
cycl-isopropylidene malonate
2033-24-1

cycl-isopropylidene malonate

cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

2,3-diamino-N-(3-fluoro-4-(phenylamino)phenyl)benzamide

2,3-diamino-N-(3-fluoro-4-(phenylamino)phenyl)benzamide

C29H28FN5O4

C29H28FN5O4

Conditions
ConditionsYield
In 1,2-dichloro-ethane Inert atmosphere; Reflux;56%
cycl-isopropylidene malonate
2033-24-1

cycl-isopropylidene malonate

cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

2,3-diamino-N-(2-naphthyl)benzamide

2,3-diamino-N-(2-naphthyl)benzamide

C27H26N4O4

C27H26N4O4

Conditions
ConditionsYield
In 1,2-dichloro-ethane Inert atmosphere; Reflux;56%
N-((1H-imidazol-2-yl)methyl)-1-phenylmethanamine

N-((1H-imidazol-2-yl)methyl)-1-phenylmethanamine

cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

isobutyraldehyde
78-84-2

isobutyraldehyde

(E)-N-(7-benzyl-6-isopropyl-7,8-dihydroimidazo[1,2-a]pyrazin-5(6H)-ylidene)cyclopropanamine

(E)-N-(7-benzyl-6-isopropyl-7,8-dihydroimidazo[1,2-a]pyrazin-5(6H)-ylidene)cyclopropanamine

Conditions
ConditionsYield
In methanol at 20℃; for 18h; Inert atmosphere;56%
tert-butyl 1-formyl-3-methoxycyclobutylcarbamate
1232365-54-6

tert-butyl 1-formyl-3-methoxycyclobutylcarbamate

cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

tert-butyl 1-(2-(cyclopropylamino)-1-hydroxy-2-oxoethyl)-3-methoxycyclobutylcarbamate
1232365-55-7

tert-butyl 1-(2-(cyclopropylamino)-1-hydroxy-2-oxoethyl)-3-methoxycyclobutylcarbamate

Conditions
ConditionsYield
With pyridine; trifluoroacetic acid In dichloromethane Cooling with ice;54%
Stage #1: tert-butyl 1-formyl-3-methoxycyclobutylcarbamate; cyclopropyl isocyanide With pyridine; trifluoroacetic acid In dichloromethane Cooling with ice;
Stage #2: With lithium hydroxide In 1,4-dioxane
Stage #3: With citric acid In 1,4-dioxane
54%
With pyridine; trifluoroacetic acid In dichloromethane at 20℃; Cooling with ice;54%
2-methylnicotinaldehyde
60032-57-7

2-methylnicotinaldehyde

cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

N-cyclopropyl-1-(3-(trifluoromethyl)phenyl)-cyclopropan-1-amine

N-cyclopropyl-1-(3-(trifluoromethyl)phenyl)-cyclopropan-1-amine

N-cyclopropyl-N-((1-cyclopropyl-1H-tetrazol-5-yl)(2-methylpyridin-3-yl)methyl)-1-(3-(trifluoromethyl)phenyl)cyclopropan-1-amine

N-cyclopropyl-N-((1-cyclopropyl-1H-tetrazol-5-yl)(2-methylpyridin-3-yl)methyl)-1-(3-(trifluoromethyl)phenyl)cyclopropan-1-amine

Conditions
ConditionsYield
With trimethylsilylazide In methanol at 20℃; Ugi Condensation; Inert atmosphere;52%
cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

phenylacetaldehyde
122-78-1

phenylacetaldehyde

N-cyclopropyl-2-hydroxy-3-phenylpropanamide

N-cyclopropyl-2-hydroxy-3-phenylpropanamide

Conditions
ConditionsYield
With 2-(hydroxymethyl)benzoic acid In dichloromethane Passerini Condensation; Reflux;51%
cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

benzoyl chloride
98-88-4

benzoyl chloride

(1-cyclopropyl-1H-tetrazol-5-yl)(phenyl)methanone
1346110-82-4

(1-cyclopropyl-1H-tetrazol-5-yl)(phenyl)methanone

Conditions
ConditionsYield
With pyridine; sodium azide In water at 100℃; for 0.2h; sealed tube; microwave irradiation;49%
cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

tert-butyl-(3S)-3,6-dimethyl-4-[(2-nitrophenyl)sulfonyl]-1,2,3,4-tetrahydropyrazine-1-carbamate

tert-butyl-(3S)-3,6-dimethyl-4-[(2-nitrophenyl)sulfonyl]-1,2,3,4-tetrahydropyrazine-1-carbamate

(2S,5S)-N-cyclopropyl-2,5-dimethyl-4-(2-nitrobenzenesulfonyl)-1-(trifluoroacetyl)piperazine-2-carboxamide

(2S,5S)-N-cyclopropyl-2,5-dimethyl-4-(2-nitrobenzenesulfonyl)-1-(trifluoroacetyl)piperazine-2-carboxamide

Conditions
ConditionsYield
Stage #1: tert-butyl-(3S)-3,6-dimethyl-4-[(2-nitrophenyl)sulfonyl]-1,2,3,4-tetrahydropyrazine-1-carbamate With trifluoroacetic acid at 20℃;
Stage #2: cyclopropyl isocyanide In ethanol at 0 - 20℃;
49%
cycl-isopropylidene malonate
2033-24-1

cycl-isopropylidene malonate

cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

3-fluoro-4-phenoxyphenyl 2,3-diaminobenzoate

3-fluoro-4-phenoxyphenyl 2,3-diaminobenzoate

C29H26FN3O6

C29H26FN3O6

Conditions
ConditionsYield
In 1,2-dichloro-ethane Inert atmosphere; Reflux;48%
cycl-isopropylidene malonate
2033-24-1

cycl-isopropylidene malonate

cyclopropyl isocyanide
58644-53-4

cyclopropyl isocyanide

C12H12N2O2S

C12H12N2O2S

C22H23N3O5S

C22H23N3O5S

Conditions
ConditionsYield
In 1,2-dichloro-ethane Inert atmosphere; Reflux;48%

Raw Materials

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