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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

5-Nitrothiophene-2-carboxylic acid Manufacturer/High quality/Best price/In stock

Cas:6317-37-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay 98%min ---------------------------------------------------------------------------------------------

High purity Various Specifications 5-nitrothiophene-2-carboxylic acid CAS:6317-37-9

Cas:6317-37-9

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Manufacturers

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

5-Nitrothiophene-2-Carboxylic Acid

Cas:6317-37-9

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

ANQING CHICO PHARMACEUTICAL CO.,LTD.

High quality. Factory supply. In stock. Best price.1.Quick response within 24 hours;2.Best quality in your requirement;?3.We pay more attention on delivery time, and usually ship on time;4.Under the premise of safety and effectiveness, we can produce

5-Nitrothiophene-2-carboxylic acid

Cas:6317-37-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

5-Nitro-2-thiophenecarboxylic acid

Cas:6317-37-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.

CAS No.6317-37-9 5-Nitrothiophene-2-carboxylic acid

Cas:6317-37-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 6317-37-9 with competitive price

Cas:6317-37-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by email in time prod

5-Nitrothiophene-2-carboxylic acid

Cas:6317-37-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

5-Nitrothiophene-2-carboxylic acid CAS:6317-37-9

Cas:6317-37-9

Min.Order:1 Metric Ton

FOB Price: $380.0 / 590.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

1. Specifications Appearance & Physical State: Light yellow crystal powder MF: C5H2NO4S Melting Point: 154-159℃ MW: 172.1392

5-Nitrothiophene-2-carboxylic acid CAS: 6317-37-9

Cas:6317-37-9

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 5-Nitrothiophene-2-carboxylic acid Synonyms: RARECHEM AL BO 0544;5-Nitro-2-thenoic acid;5-NITRO-2-THIOPHENECARBOXYLIC ACID;5-NITROTHIOPHENE-2-CARBOXYLIC ACID;BUTTPARK 121\04-13;5-Nitro-2-ThiphenecarboxylicAcid;5-nitro-2-thiophenec

5-Nitrothiophene-2-carboxylic acid

Cas:6317-37-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

5-Nitrothiophene-2-carboxylic acid CAS:6317-37-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality

5-Nitrothiophene-2-carboxylic acid CAS:6317-37-9

Cas:6317-37-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,

5-Nitro-2-thiophenecarboxylic acidCAS NO.: 6317-37-9

Cas:6317-37-9

Min.Order:20 Metric Ton

Negotiable

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:6317-37-9

Cas:6317-37-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures

5-Nitrothiophene-2-carboxylic acid

Cas:6317-37-9

Min.Order:1 Kilogram

FOB Price: $40.0 / 60.0

Type:Lab/Research institutions

inquiry

Nanjing Fred Technology Co.,Ltd.

5-Ntrothiophene-2-carboxylic acid is one of the most competitive products in our company, we can supply it with good quality and best price. Appearance:White to light brown solid Storage:Room temperature, Keep in Dark Place. Package:Kilograms/MT Appl

5-ntrothiophene-2-carboxylic acid

Cas:6317-37-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

5-NITROTHIOPHENE-2-CARBOXYLIC ACID

Cas:6317-37-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

5-Nitrothiophene-2-carboxylic acid

Cas:6317-37-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

6317-37-9--5-Nitrothiophene-2-carboxylic acid Appearance:White Powder Storage:Room temperature Package:according to customers' requirements Application:Pharmaceutical intermediates,API Transportation:By air(EMS or EUB or FedEx or TNT ect...) or by

6317-37-9--5-Nitrothiophene-2-carboxylic acid

Cas:6317-37-9

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

5-Nitrothiophene-2-carboxylic acid

Cas:6317-37-9

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

5-Nitrothiophene-2-carboxylic acid

Cas:6317-37-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

5-Nitrothiophene-2-carboxylic acid

Cas:6317-37-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

5-Nitro-2-thiophenecarboxylic acidCAS NO.: 6317-37-9 CAS NO.6317-37-9

Cas:6317-37-9

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

5-Nitrothiophene-2-carboxylic acid

Cas:6317-37-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

5-Nitrothiophene-2-carboxylic acid

Cas:6317-37-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

2-Thiophenecarboxylicacid, 5-nitro-

Cas:6317-37-9

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

5-Nitro Thiophene-2-Carboxylic Acid cas no. 6317-37-9 98%

Cas:6317-37-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

5-nitrothiophene-2-carboxylic acid

Cas:6317-37-9

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

5-Nitrothiophene-2-carboxylic acid

Cas:6317-37-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

5-Nitrothiophene-2-carboxylic acid

Cas:6317-37-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

(5-nitrothiophen-2-yl)methanol
20898-85-5

(5-nitrothiophen-2-yl)methanol

5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

Conditions
ConditionsYield
With silica-supported Jones reagent In dichloromethane for 0.035h;99.7%
5-nitro-2-thiophenecarboxaldehyde
4521-33-9

5-nitro-2-thiophenecarboxaldehyde

5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

Conditions
ConditionsYield
With bromine; sodium acetate; acetic acid98.5%
With hydrogenchloride; bromine; sodium hydroxide In water98.2%
With sodium hypobromide; sodium acetate; acetic acid92%
2-thiophenylcarboxylic acid
527-72-0

2-thiophenylcarboxylic acid

A

5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

B

4-nitro-2-thiophenecarboxylic acid
13138-70-0

4-nitro-2-thiophenecarboxylic acid

Conditions
ConditionsYield
With nitric acid; acetic anhydride; acetic acid at 20℃; for 4h; Nitration;A 17%
B 34%
With sulfuric acid; nitric acid at 0 - 10℃; for 1.25h;
With sulfuric acid; nitric acid at 10 - 20℃;A n/a
B 18.2 g
With sulfuric acid; nitric acid at 10 - 20℃; Overall yield = 18.2 g;
5-nitro-2-thienyl cyanide
16689-02-4

5-nitro-2-thienyl cyanide

5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

Conditions
ConditionsYield
With hydrogenchloride
2-acetyl-5-nitrothiophene
39565-00-9

2-acetyl-5-nitrothiophene

A

5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

B

(5-nitro-[2]thienyl)-glyoxylic acid

(5-nitro-[2]thienyl)-glyoxylic acid

Conditions
ConditionsYield
With nitric acid
2-thiophenylcarboxylic acid
527-72-0

2-thiophenylcarboxylic acid

nitric acid
7697-37-2

nitric acid

acetic anhydride
108-24-7

acetic anhydride

A

2-nitrothiophene
609-40-5

2-nitrothiophene

B

5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

C

4-nitro-2-thiophenecarboxylic acid
13138-70-0

4-nitro-2-thiophenecarboxylic acid

Conditions
ConditionsYield
at -5℃;
2-thiophenylcarboxylic acid
527-72-0

2-thiophenylcarboxylic acid

A

5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

B

4-nitro-thiophene-2-carboxylic acid ; 2-nitro-thiophene

4-nitro-thiophene-2-carboxylic acid ; 2-nitro-thiophene

Conditions
ConditionsYield
With nitric acid; acetic anhydride at -5℃;
2-thiophenecarboxaldehyde diacetate
63011-97-2

2-thiophenecarboxaldehyde diacetate

5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: acetic acid anhydride; nitric acid; acetic acid
2: aqueous sulfuric acid
3: aqueous potassium permanganate solution; aq. NaOH solution
View Scheme
5-nitrothiophene-2-carboxaldehyde diacetate
14289-24-8

5-nitrothiophene-2-carboxaldehyde diacetate

5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aqueous sulfuric acid
2: aqueous potassium permanganate solution; aq. NaOH solution
View Scheme
Multi-step reaction with 2 steps
1: ethanol; sulfuric acid
2: chromium (VI)-oxide; aqueous sulfuric acid / 110 °C
View Scheme
2-thiophenylcarboxylic acid
527-72-0

2-thiophenylcarboxylic acid

5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

sodium chlorite
7758-19-2

sodium chlorite

5-nitro-2-thiophenecarboxaldehyde
4521-33-9

5-nitro-2-thiophenecarboxaldehyde

sodium dihydrogen phosphate

sodium dihydrogen phosphate

5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

Conditions
ConditionsYield
With dihydrogen peroxide; sodium thiosulfate In water; acetonitrile
sodium dihydrogenphosphate
10049-21-5

sodium dihydrogenphosphate

5-nitro-2-thiophenecarboxaldehyde
4521-33-9

5-nitro-2-thiophenecarboxaldehyde

dihydrogen peroxide
7722-84-1

dihydrogen peroxide

5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

Conditions
ConditionsYield
With hydrogenchloride; NaClO2; sodium sulfite In water; acetonitrile
5-nitro-2-thiophenecarboxaldehyde
4521-33-9

5-nitro-2-thiophenecarboxaldehyde

jones reagent

jones reagent

5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

Conditions
ConditionsYield
In water; isopropyl alcohol; acetone967 mg (90%)
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

5-nitrothiophene-2-carbonyl chloride
39978-57-9

5-nitrothiophene-2-carbonyl chloride

Conditions
ConditionsYield
With oxalyl dichloride Reflux;100%
With thionyl chloride Reflux;100%
With thionyl chloride
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

ethanol
64-17-5

ethanol

5-nitro-2-thiophenecarboxylic acid ethyl ester
5751-84-8

5-nitro-2-thiophenecarboxylic acid ethyl ester

Conditions
ConditionsYield
With hydrogenchloride In water for 1.5h; Reflux;98.3%
Stage #1: 5-nitrothiophene-2-carboxylic acid With thionyl chloride for 3h; Heating / reflux;
Stage #2: ethanol for 3h; Heating / reflux;
96%
In methanol Reflux;
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

(5-nitrothiophen-2-yl)methanol
20898-85-5

(5-nitrothiophen-2-yl)methanol

Conditions
ConditionsYield
With borane-THF In tetrahydrofuran at 20℃; for 16h; Inert atmosphere; Cooling with ice;98%
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

4-isopropyl-1-methylcyclohex-3-en-1-amine

4-isopropyl-1-methylcyclohex-3-en-1-amine

N-(4-isopropyl-1-methylcyclohex-3-en-1-yl)-5-nitrothiophene-2-carboxamide

N-(4-isopropyl-1-methylcyclohex-3-en-1-yl)-5-nitrothiophene-2-carboxamide

Conditions
ConditionsYield
Stage #1: 5-nitrothiophene-2-carboxylic acid With thionyl chloride; N,N-dimethyl-formamide In dichloromethane Reflux;
Stage #2: 4-isopropyl-1-methylcyclohex-3-en-1-amine With triethylamine In dichloromethane; N,N-dimethyl-formamide Reflux;
96.39%
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

(S)-N-[[3-[3-fluoro-4-(1-piperazinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide
154590-66-6

(S)-N-[[3-[3-fluoro-4-(1-piperazinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide

C21H22FN5O6S

C21H22FN5O6S

Conditions
ConditionsYield
With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 0 - 20℃; for 18h;93%
methanol
67-56-1

methanol

5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

methyl 5-nitrothiophene-2-carboxylate
5832-01-9

methyl 5-nitrothiophene-2-carboxylate

Conditions
ConditionsYield
With sulfuric acid for 48h; Heating;91%
With hydrogenchloride
With thionyl chloride
In methanol Reflux;
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

dimethyl sulfate
77-78-1

dimethyl sulfate

methyl 5-nitrothiophene-2-carboxylate
5832-01-9

methyl 5-nitrothiophene-2-carboxylate

Conditions
ConditionsYield
With potassium carbonate In DMF (N,N-dimethyl-formamide); acetone at 100℃; for 1h;89%
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

diethyl-L-glutamate hydrochloride
1118-89-4

diethyl-L-glutamate hydrochloride

N-(5-nitro-2-thiophenecarbonyl)-L-glutamic acid diethyl ester
106585-64-2

N-(5-nitro-2-thiophenecarbonyl)-L-glutamic acid diethyl ester

Conditions
ConditionsYield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In dichloromethane for 2h; Ambient temperature;88%
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

2-methoxy-6-pentadecylaniline

2-methoxy-6-pentadecylaniline

N-(2-methoxy-6-pentadecylphenyl)-5-nitrothiophene-2-carboxamide

N-(2-methoxy-6-pentadecylphenyl)-5-nitrothiophene-2-carboxamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 2h; Inert atmosphere;88%
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

2-methoxy-6-octylaniline

2-methoxy-6-octylaniline

N-(2-methoxy-6-octylphenyl)-5-nitrothiophene-2-carboxamide

N-(2-methoxy-6-octylphenyl)-5-nitrothiophene-2-carboxamide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 2h; Inert atmosphere;87%
2-{1-[3,5-difluoro-4-(1,2,3,6-tetrahydro-pyridin-4-yl)-phenyl]-1H-[1,2,3]triazol-4-ylmethyl}-isoindole-1,3-dione
864145-50-6

2-{1-[3,5-difluoro-4-(1,2,3,6-tetrahydro-pyridin-4-yl)-phenyl]-1H-[1,2,3]triazol-4-ylmethyl}-isoindole-1,3-dione

5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

2-(1-{3,5-difluoro-4-[1-(5-nitro-thiophene-2-carbonyl)-1,2,3,6-tetrahydro-pyridin-4-yl]-phenyl}-1H-[1,2,3]triazol-4-ylmethyl)-isoindole-1,3-dione

2-(1-{3,5-difluoro-4-[1-(5-nitro-thiophene-2-carbonyl)-1,2,3,6-tetrahydro-pyridin-4-yl]-phenyl}-1H-[1,2,3]triazol-4-ylmethyl)-isoindole-1,3-dione

Conditions
ConditionsYield
Stage #1: 5-nitrothiophene-2-carboxylic acid With thionyl chloride for 1h; Heating / reflux;
Stage #2: 2-{1-[3,5-difluoro-4-(1,2,3,6-tetrahydro-pyridin-4-yl)-phenyl]-1H-[1,2,3]triazol-4-ylmethyl}-isoindole-1,3-dione With triethylamine In tetrahydrofuran at 0 - 35℃; for 12h;
80%
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

L-glutamic acid diethyl ester
16450-41-2

L-glutamic acid diethyl ester

N-(5-nitro-2-thiophenecarbonyl)-L-glutamic acid diethyl ester
106585-64-2

N-(5-nitro-2-thiophenecarbonyl)-L-glutamic acid diethyl ester

Conditions
ConditionsYield
Stage #1: 5-nitrothiophene-2-carboxylic acid With thionyl chloride for 3h; Reflux;
Stage #2: L-glutamic acid diethyl ester With triethylamine In dichloromethane at 0 - 5℃; for 1h;
79.9%
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

C13H12N4O4S

C13H12N4O4S

5-nitro-N-(4-(5-(5-nitrothiophen-2-yl)-1,2,4-oxadiazol-3-yl)benzyl)thiophene-2-carboxamide

5-nitro-N-(4-(5-(5-nitrothiophen-2-yl)-1,2,4-oxadiazol-3-yl)benzyl)thiophene-2-carboxamide

Conditions
ConditionsYield
With dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 0 - 20℃; for 12h;78%
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

2-(3,4-dimethoxyphenyl)-ethylamine
120-20-7

2-(3,4-dimethoxyphenyl)-ethylamine

N-(3,4-dimethoxyphenethyl)-5-nitrothiophene-2-carboxamide
93988-49-9

N-(3,4-dimethoxyphenethyl)-5-nitrothiophene-2-carboxamide

Conditions
ConditionsYield
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine In N,N-dimethyl-formamide at 20℃; for 2h;74%
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

4-(4-(tert-butyl)phenyl)-5-(4-fluorophenyl)thiazol-2-amine

4-(4-(tert-butyl)phenyl)-5-(4-fluorophenyl)thiazol-2-amine

N-(4-(4-(tert-butyl)phenyl)-5-(4-fluorophenyl)thiazol-2-yl)-5-nitrothiophene-2-carboxamide

N-(4-(4-(tert-butyl)phenyl)-5-(4-fluorophenyl)thiazol-2-yl)-5-nitrothiophene-2-carboxamide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; Inert atmosphere;74%
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

4-amino-2-thiophenecarboxylic acid
89499-38-7

4-amino-2-thiophenecarboxylic acid

Conditions
ConditionsYield
With hydrogenchloride; tin(ll) chloride at 20℃; for 6h; Reduction;67%
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

1-(5-nitrothiazol-2-yl)piperidin-4-amine
1601751-76-1

1-(5-nitrothiazol-2-yl)piperidin-4-amine

5-nitro-N-(1-(5-nitrothiazol-2-yl)piperidin-4-yl)thiophene-2-carboxamide
1624309-47-2

5-nitro-N-(1-(5-nitrothiazol-2-yl)piperidin-4-yl)thiophene-2-carboxamide

Conditions
ConditionsYield
With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; triethylamine In dichloromethane; ethyl acetate at 0 - 20℃; for 6h;65.5%
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

C14H19ClN2O3
1312205-19-8

C14H19ClN2O3

C19H21N3O7S
1274572-94-9

C19H21N3O7S

Conditions
ConditionsYield
With dmap In N,N-dimethyl-formamide at 80℃; for 6h;64%
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

(4-aminomethyl)aniline
4403-71-8

(4-aminomethyl)aniline

5-nitro-N-(4-(5-nitrothiophene-2-carboxamido)benzyl)thiophene-2-carboxamide

5-nitro-N-(4-(5-nitrothiophene-2-carboxamido)benzyl)thiophene-2-carboxamide

Conditions
ConditionsYield
With dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 0℃; for 24h;63%
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

N-tert-butylchloroacetamide
15678-99-6

N-tert-butylchloroacetamide

C11H14N2O5S
1274572-90-5

C11H14N2O5S

Conditions
ConditionsYield
With dmap In N,N-dimethyl-formamide at 80℃; for 6h;61%
3-(1H-imidazol-1-yl)propan-1-amine
5036-48-6

3-(1H-imidazol-1-yl)propan-1-amine

5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

N-(3-(1H-imidazol-1-yl)propyl)-5-nitrothiophene-2-carboxamide

N-(3-(1H-imidazol-1-yl)propyl)-5-nitrothiophene-2-carboxamide

Conditions
ConditionsYield
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine In N,N-dimethyl-formamide at 20℃; for 2h;59%
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

C14H19ClN2O3
1312205-12-1

C14H19ClN2O3

C19H21N3O7S
1274572-93-8

C19H21N3O7S

Conditions
ConditionsYield
With dmap In N,N-dimethyl-formamide at 80℃; for 6h;58%
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

3-amino-6-trifluoromethylquinoxaline-2-carbonitrile-N1,N4-dioxide

3-amino-6-trifluoromethylquinoxaline-2-carbonitrile-N1,N4-dioxide

C15H6F3N5O5S
1207614-18-3

C15H6F3N5O5S

Conditions
ConditionsYield
Stage #1: 5-nitrothiophene-2-carboxylic acid; 3-amino-6-trifluoromethylquinoxaline-2-carbonitrile-N1,N4-dioxide In N,N-dimethyl-formamide at 20℃;
Stage #2: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide
Stage #3: With dmap
57.9%
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

chloroacetone
78-95-5

chloroacetone

C8H7NO5S
1274572-95-0

C8H7NO5S

Conditions
ConditionsYield
With dmap In N,N-dimethyl-formamide at 80℃; for 6h;56%
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

1-(4-fluorophenylmethyl)piperazine
70931-28-1

1-(4-fluorophenylmethyl)piperazine

[4-(4-fluorobenzyl)piperazin-1-yl](5-nitro-2-thienyl)methanone

[4-(4-fluorobenzyl)piperazin-1-yl](5-nitro-2-thienyl)methanone

Conditions
ConditionsYield
Stage #1: 5-nitrothiophene-2-carboxylic acid With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 1h;
Stage #2: 1-(4-fluorophenylmethyl)piperazine With triethylamine In N,N-dimethyl-formamide at 50℃; for 0.166667h; Microwave irradiation;
55%
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

3-amino-6-trifluoromethylquinoxaline-2-carbonitrile-N1,N4-dioxide

3-amino-6-trifluoromethylquinoxaline-2-carbonitrile-N1,N4-dioxide

C15H6F3N5O5S
1207614-17-2

C15H6F3N5O5S

Conditions
ConditionsYield
Stage #1: 5-nitrothiophene-2-carboxylic acid; 3-amino-6-trifluoromethylquinoxaline-2-carbonitrile-N1,N4-dioxide In N,N-dimethyl-formamide at 20℃;
Stage #2: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide
Stage #3: With dmap
51.8%
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

1-chloro-3,3-dimethyl-butan-2-one
13547-70-1

1-chloro-3,3-dimethyl-butan-2-one

C11H13NO5S
1274572-97-2

C11H13NO5S

Conditions
ConditionsYield
With dmap In N,N-dimethyl-formamide at 80℃; for 6h;48%
5-nitrothiophene-2-carboxylic acid
6317-37-9

5-nitrothiophene-2-carboxylic acid

C13H10N2O5S

C13H10N2O5S

5-nitro-N-(4-((5-nitrothiophen-2-yl)carbamoyl)benzyl)thiophene-2-carboxamide

5-nitro-N-(4-((5-nitrothiophen-2-yl)carbamoyl)benzyl)thiophene-2-carboxamide

Conditions
ConditionsYield
With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 0 - 20℃; for 2h;46%

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