GMP factoryFull experience of large numbers containers loading in main Chinese seaports Packing with pallet as buyer's special request Best service after shipment with e-mail Cargos together with container sales seervice available Rich experience for
Cas:65277-42-1
Min.Order:0
Negotiable
Type:Other
inquiryDayangchem’s R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantiti
Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:65277-42-1
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:65277-42-1
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiryISO Factory/Good qualityAppearance:off white Storage:dry and cool place Package:10G/BAG; 1KG/BAG ;25KG/DRUM Application:Active pharaceutical ingredients Transportation:BY SEA,AIR,EXPRESS Port:shenzhen/shanghai
Strict quality control: good raw materials, good quality, Zenuo Biology has always regarded quality as the life of the enterprise. Zenuo Biology has an independent quality control department and long-term cooperation with the third-party detection
Cas:65277-42-1
Min.Order:100 Gram
Negotiable
Type:Trading Company
inquiryShanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu
Cas:65277-42-1
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Manufacturers
inquiryQuick Details CAS No.: 65277-42-1 Other Names: ketoconazole MF: C26H28Cl2N4O4 EINECS No.: 265-667-4 Place of Origin:
1. A strong scientific research team . 2. Stable quality (with a complete scientific research center and testing center to ensure the quality stability of each batch of products). 3. Rich export experience (with practical experience in exporting to m
Cas:65277-42-1
Min.Order:1 Kilogram
FOB Price: $6.5 / 6.6
Type:Trading Company
inquiryWhy is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c
Cas:65277-42-1
Min.Order:1 Kilogram
FOB Price: $15.0 / 65.0
Type:Trading Company
inquiryItems Standard Result Characters A white or almost white powder Conform Practically insoluble in water,f
Cas:65277-42-1
Min.Order:1 Gram
FOB Price: $100.0 / 500.0
Type:Manufacturers
inquirySpecifications: Ketoconazole CAS 65277-42-1 CAS 65277-42-1 Brand: Renyoung MF C26H28Cl2N4O4 Molecular Weight:531.44 Min order: 10
1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:Off-white to white powder Storage:2-8°C Package:1kg/foil bag;
Cas:65277-42-1
Min.Order:5 Kilogram
FOB Price: $100.0 / 180.0
Type:Trading Company
inquiryD - glucuronic acid and N - acetyl glucosamine disaccharides unit composed of hyaluronic acid (Hyaluronan), also called uronic acid, hyaluronic acid, basic structure is made up of two disaccharides unit D - glucuronic acid and N - acetyl glucosamin
We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C
Cas:65277-42-1
Min.Order:1 Gram
Negotiable
Type:Manufacturers
inquiryXi’an Quanao Biotech Co., Ltd. with 18 years experience in plant extract filed. Product grade: Medicine, Health care product, Cosmetics, Food, Beverage, Feed. Hot selling market: Europe, North America, South America, Middle East, Asia Pacifi
Cas:65277-42-1
Min.Order:1 Kilogram
FOB Price: $99.0 / 119.0
Type:Manufacturers
inquiry1.strict Quality control: Strictly in accordance with Chinese GMP(2010 version), guidelines issued by FDA,EDQM, and ICH relevant regulations, we have established a sound quality assurance system, implementing regular supervision and management in
Cas:65277-42-1
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryhigh quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai
Ketoconazole English name: Ketoconazole Chemical name: cis-1-Acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine Category involved:
The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
ADVANTAGE: 1. More than 3,000 Chinese medicine reference substances / standard products available from stock, issued on the same day, multiple cities can be delivered the next day 2. The products are provided with COA, HPLC, NMR, quality assurance,
Name:ketoconazole CAS NO: 65277-42-1 Grade:Medical scientific research and export Molecular formula:C26H28Cl2N4O4 Molecular weight: 531.4309 Product Quality 12 years of chemical raw materials Mature operation of the industry System stabili
Cas:65277-42-1
Min.Order:25 Kilogram
FOB Price: $2.0 / 3.0
Type:Other
inquiryHenan Tianfu Chemical Co., Ltd. is located in Zhengzhou High-tech Development Zone with import and export license. We passed ISO 9001:2008 in 2009, and won "High-tech Enterprise" by provincial government in 2013.The objective of the com
Cas:65277-42-1
Min.Order:1 Gram
FOB Price: $1000.0
Type:Lab/Research institutions
inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
Cas:65277-42-1
Min.Order:1 Kilogram
FOB Price: $1.0 / 10.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:65277-42-1
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
Cas:65277-42-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryProuduct name: Ketoconazole CAS: 65277-42-1 Appearance: White or almost white crystal powder Purity: 98.5%min Appearance:White powder Storage:Store in cool and dry place, away from sun light. Package:drum Application:Antibiotic; Antifungal
Appearance:Almost white crystalline powder Storage:ln stock Package:25kg/Carton Application:Chemicals Transportation:Express/Sea/Air Port:Any port in china
Cas:65277-42-1
Min.Order:25 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryOur Adwantage: 1.We have stock so we can delivery quickly at the very day when receive the payment. 2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order. 3.High quality gua
Cas:65277-42-1
Min.Order:10 Gram
Negotiable
Type:Other
inquiry1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanone
ketoconazole
Conditions | Yield |
---|---|
With trifluoroacetic acid In dimethyl sulfoxide; toluene for 16h; Reagent/catalyst; Temperature; Reflux; | 80% |
1H-imidazole
(2R,4S)-cis-2-(bromomethyl)-2-(2,4-dichlorophenyl)-4-<<4-(4-acetylpiperazin-1-yl)phenoxy>methyl>-1,3-dioxolane
A
ketoconazole
B
(2R,4S)-cis-2-(hydroxymethyl)-2-(2,4-dichlorophenyl)-4-<<4-(4-acetylpiperazin-1-yl)phenoxy>methyl>-1,3-dioxolane
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl acetamide for 4h; Heating; | A 53% B 10% |
(2R,4R)-(+)-<2-(2,4-dichlorophenyl)-2-<(1H-imidazol-1-yl)methyl>-1,3-dioxolan-4-yl>methyl methanesulfonate
N-acetyl-N'-(4-hydroxyphenyl)piperazine
ketoconazole
Conditions | Yield |
---|---|
With sodium hydride 1.) DMSO, RT, 1 h, 2.) DMSO, 80 deg C, 4 h; Yield given. Multistep reaction; |
Conditions | Yield |
---|---|
With sodium hydride In dimethyl sulfoxide at 0 - 80℃; |
1-(4-hydroxyphenyl)piperazine
ketoconazole
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: pyridine / CH2Cl2 2: K2CO3 / methanol / 20 °C 3: NaH / dimethylsulfoxide / 0 - 80 °C View Scheme |
1-(4-Acetoxyphenyl)-4-acetylpiperazine
ketoconazole
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: K2CO3 / methanol / 20 °C 2: NaH / dimethylsulfoxide / 0 - 80 °C View Scheme |
(2R,4R)-(+)-<2-(2,4-dichlorophenyl)-2-<(1H-imidazol-1-yl)methyl>-1,3-dioxolan-4-yl>methyl benzoate
ketoconazole
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: NaOH / dioxane / Heating 2: pyridine 3: NaH / dimethylsulfoxide / 0 - 80 °C View Scheme |
(2R,4S)-(+)-2-(2,4-dichlorophenyl)-2-<(1H-imidazol-1-yl)methyl>-1,3-dioxolane-4-methanol
ketoconazole
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: pyridine 2: NaH / dimethylsulfoxide / 0 - 80 °C View Scheme | |
Multi-step reaction with 2 steps 1: 81 percent / pyridine / 16 h / 0 °C 2: 1.) NaH / 1.) DMSO, RT, 1 h, 2.) DMSO, 80 deg C, 4 h View Scheme |
ketoconazole
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 89 percent / 50percent aq. NaOH / dioxane / 0.5 h / Heating 2: 81 percent / pyridine / 16 h / 0 °C 3: 1.) NaH / 1.) DMSO, RT, 1 h, 2.) DMSO, 80 deg C, 4 h View Scheme |
1-(4-{4-[2-(2,4-dichloro-phenyl)-2-imidazol-1-ylmethyl-[1,3]dioxolan-4-ylmethoxy]-phenyl}-piperazin-1-yl)-ethanone
A
ketoconazole
B
(2R,4R)-Ketoconazole
D
(2S,4S)-Ketoconazole
Conditions | Yield |
---|---|
With methanol; sodium dodecyl-sulfate; 2,3,6-trimethyl-beta-cyclodextrin; sodium hydroxide In aq. phosphate buffer at 25℃; pH=2.5; pH-value; Reagent/catalyst; Temperature; Resolution of racemate; |
A
ketoconazole
Conditions | Yield |
---|---|
With Beckman P/ACE MDQ Capillary Electrophoresis System equipped fused-silica capillaries (Polymicro Technologies, Phoenix, Arizona) of 50-μm ID cut with sulfobutyl ether β-cyclodextrin as chiral selector In aq. buffer at 25℃; pH=2.5; Concentration; pH-value; Reagent/catalyst; Resolution of racemate; |
N-acetyl-N'-(4-hydroxyphenyl)piperazine
ketoconazole
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: sodium hydroxide; tetrabutylammomium bromide / water; toluene / 16 h / 25 °C 2: trifluoroacetic acid / toluene; dimethyl sulfoxide / 16 h / Reflux View Scheme |
1,3-Dichlorobenzene
ketoconazole
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: aluminum (III) chloride / dichloromethane / 0.5 h / 25 °C 1.2: 16 h / Reflux 2.1: triethylamine / dichloromethane / 10 °C 3.1: trifluoroacetic acid / toluene; dimethyl sulfoxide / 16 h / Reflux View Scheme | |
Multi-step reaction with 3 steps 1.1: aluminum (III) chloride / dichloromethane / 0.5 h / 25 °C 1.2: 16 h / Reflux 2.1: triethylamine / dichloromethane / 10 °C 3.1: trifluoroacetic acid / toluene; dimethyl sulfoxide / 16 h / Reflux View Scheme |
2,4-dichlorophenacyl bromide
ketoconazole
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: triethylamine / dichloromethane / 10 °C 2: trifluoroacetic acid / toluene; dimethyl sulfoxide / 16 h / Reflux View Scheme |
ketoconazole
A
ketoconazole
Conditions | Yield |
---|---|
With cellulose (3,5-dimethylphenylcarbamate) coated reduced graphene oxide(at)silica gel In hexane at 25℃; Resolution of racemate; enantioselective reaction; |
Conditions | Yield |
---|---|
In methanol at 25℃; for 24h; | 94% |
Conditions | Yield |
---|---|
In methanol at 25℃; for 36h; | 89% |
Conditions | Yield |
---|---|
In methanol at 25℃; for 24h; | 86% |
bis(triphenylphosphino)copper(I) nitrate
ketoconazole
Conditions | Yield |
---|---|
In acetonitrile for 24h; | 83% |
potassium tetrachloroplatinate(II)
ketoconazole
Conditions | Yield |
---|---|
In ethanol; water at 100℃; for 2h; | 78% |
Conditions | Yield |
---|---|
at 25℃; for 24h; | 78% |
(tetrahydrothiophene)gold(I) chloride
ketoconazole
Conditions | Yield |
---|---|
In dichloromethane at 0℃; for 2h; | 65% |
Conditions | Yield |
---|---|
In methanol at 25℃; for 24h; | 65% |
Ethyl bromodifluoroacetate
ketoconazole
Conditions | Yield |
---|---|
With rongalite; sulfur In N,N-dimethyl acetamide at 100℃; for 24h; Sealed tube; | 43% |
With sulfur; rongalite In N,N-dimethyl acetamide at 100℃; for 24h; Sealed tube; | 43% |
Conditions | Yield |
---|---|
In methanol at 25℃; for 0.5h; | 38% |
ethyl bromofluoroacetate
ketoconazole
Conditions | Yield |
---|---|
With sulfur; sodium dithionite In 1,2-dichloro-ethane at 80℃; for 24h; Sealed tube; | 37% |
With sulfur; sodium dithionite In 1,2-dichloro-ethane at 100℃; for 24h; Sealed tube; | 37% |
ketoconazole
Conditions | Yield |
---|---|
With potassium hydroxide In isopropyl alcohol | |
With sodium hydroxide In methanol Reflux; | 700 mg |
ketoconazole
Conditions | Yield |
---|---|
With iodine In 1,4-dioxane at 24.84 - 39.84℃; Kinetics; Equilibrium constant; Thermodynamic data; Solvent; |
ketoconazole
2,4-diamino-6-piperidinopyrimidine 3-oxide
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