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Wuxi TAA Chemical Industry Co.,LTD.

GMP factoryFull experience of large numbers containers loading in main Chinese seaports Packing with pallet as buyer's special request Best service after shipment with e-mail Cargos together with container sales seervice available Rich experience for

good quality and low price Ketoconazole factory

Cas:65277-42-1

Min.Order:0

Negotiable

Type:Other

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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem’s R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantiti

Ketoconazole

Cas:65277-42-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Ketoconazole

Cas:65277-42-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% ketoconazole 65277-42-1 GMP manufacturer

Cas:65277-42-1

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Hubei Vanz Pharm Co.,Ltd

ISO Factory/Good qualityAppearance:off white Storage:dry and cool place Package:10G/BAG; 1KG/BAG ;25KG/DRUM Application:Active pharaceutical ingredients Transportation:BY SEA,AIR,EXPRESS Port:shenzhen/shanghai

Ketoconazole

Cas:65277-42-1

Min.Order:0

Negotiable

Type:Manufacturers

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Wuhan Zenuo Biological Medicine Technology Co Ltd

Strict quality control: good raw materials, good quality, Zenuo Biology has always regarded quality as the life of the enterprise. Zenuo Biology has an independent quality control department and long-term cooperation with the third-party detection

Ketoconazole factory best quality

Cas:65277-42-1

Min.Order:100 Gram

Negotiable

Type:Trading Company

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Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Ketoconazole

Cas:65277-42-1

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Lonwin Chemical Group Limited

Quick Details CAS No.: 65277-42-1 Other Names: ketoconazole MF: C26H28Cl2N4O4 EINECS No.: 265-667-4 Place of Origin:

Ketoconazole

Cas:65277-42-1

Min.Order:100 Kilogram

FOB Price: $100.0 / 150.0

Type:Other

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Hebei Kunsui Technology Co., Ltd.

1. A strong scientific research team . 2. Stable quality (with a complete scientific research center and testing center to ensure the quality stability of each batch of products). 3. Rich export experience (with practical experience in exporting to m

CAS 65277-42-1 Hot Sale Direct Supply Antifungal Drugs Ketoconazole

Cas:65277-42-1

Min.Order:1 Kilogram

FOB Price: $6.5 / 6.6

Type:Trading Company

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Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

Hot Sale China Factory Direct Supply Antifungal Drugs Ketoconazole

Cas:65277-42-1

Min.Order:1 Kilogram

FOB Price: $15.0 / 65.0

Type:Trading Company

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Characters A white or almost white powder Conform Practically insoluble in water,f

High purity Various Specifications ketoconazole CAS:65277-42-1

Cas:65277-42-1

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Manufacturers

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Kono Chem Co.,Ltd

Specifications: Ketoconazole CAS 65277-42-1 CAS 65277-42-1 Brand: Renyoung MF C26H28Cl2N4O4 Molecular Weight:531.44 Min order: 10

Ketoconazole

Cas:65277-42-1

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Other

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Wuhan Fortuna Chemical Co.,Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:Off-white to white powder Storage:2-8°C Package:1kg/foil bag;

Hot selling Ketoconazole CAS 65277-42-1 of USP standard

Cas:65277-42-1

Min.Order:5 Kilogram

FOB Price: $100.0 / 180.0

Type:Trading Company

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Hebei yanxi chemical co.,LTD.

D - glucuronic acid and N - acetyl glucosamine disaccharides unit composed of hyaluronic acid (Hyaluronan), also called uronic acid, hyaluronic acid, basic structure is made up of two disaccharides unit D - glucuronic acid and N - acetyl glucosamin

Ketoconazole

Cas:65277-42-1

Min.Order:1000 Gram

FOB Price: $200.0

Type:Manufacturers

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

Ketoconazole manufacturer with low price

Cas:65277-42-1

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Xi'an Quanao Biotech Co., Ltd.

Xi’an Quanao Biotech Co., Ltd. with 18 years experience in plant extract filed. Product grade: Medicine, Health care product, Cosmetics, Food, Beverage, Feed. Hot selling market: Europe, North America, South America, Middle East, Asia Pacifi

Raw material 99% Ketoconazole powder price for soap cas 65277-42-1

Cas:65277-42-1

Min.Order:1 Kilogram

FOB Price: $99.0 / 119.0

Type:Manufacturers

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Hefei TNJ chemical industry co.,ltd

1.strict Quality control: Strictly in accordance with Chinese GMP(2010 version), guidelines issued by FDA,EDQM, and ICH relevant regulations, we have established a sound quality assurance system, implementing regular supervision and management in

good quality and low price Ketoconazole factory

Cas:65277-42-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

Ketoconazole

Cas:65277-42-1

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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EAST CHEMSOURCES LIMITED

Ketoconazole English name: Ketoconazole Chemical name: cis-1-Acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine Category involved:

Ketoconazole

Cas:65277-42-1

Min.Order:1 Kilogram

FOB Price: $2.0 / 3.0

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Ketoconazole

Cas:65277-42-1

Min.Order:1

Negotiable

Type:Other

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Chengdu Lemeitian Pharmaceutical Technology Co,. Ltd

ADVANTAGE: 1. More than 3,000 Chinese medicine reference substances / standard products available from stock, issued on the same day, multiple cities can be delivered the next day 2. The products are provided with COA, HPLC, NMR, quality assurance,

R41400

Cas:65277-42-1

Min.Order:5 Milligram

Negotiable

Type:Manufacturers

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Hubei DiBo chemical co., LTD

Name:ketoconazole CAS NO: 65277-42-1 Grade:Medical scientific research and export Molecular formula:C26H28Cl2N4O4 Molecular weight: 531.4309 Product Quality 12 years of chemical raw materials Mature operation of the industry System stabili

ketoconazole/ CAS:65277-42-1 / raw material/ high-quality

Cas:65277-42-1

Min.Order:25 Kilogram

FOB Price: $2.0 / 3.0

Type:Other

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Henan Tianfu Chemical Co., Ltd.

Henan Tianfu Chemical Co., Ltd. is located in Zhengzhou High-tech Development Zone with import and export license. We passed ISO 9001:2008 in 2009, and won "High-tech Enterprise" by provincial government in 2013.The objective of the com

TIANFU-CHEM - Ketoconazole

Cas:65277-42-1

Min.Order:1 Gram

FOB Price: $1000.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Ketoconazole

Cas:65277-42-1

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 65277-42-1 with best quality

Cas:65277-42-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Ketoconazole 99%

Cas:65277-42-1

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Ketoconazole/ LIDE PHARMA- Factory supply / Best price

Cas:65277-42-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Sinotech Import&Export Corporation

Prouduct name: Ketoconazole CAS: 65277-42-1 Appearance: White or almost white crystal powder Purity: 98.5%min Appearance:White powder Storage:Store in cool and dry place, away from sun light. Package:drum Application:Antibiotic; Antifungal

Ketoconazole

Cas:65277-42-1

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:Almost white crystalline powder Storage:ln stock Package:25kg/Carton Application:Chemicals Transportation:Express/Sea/Air Port:Any port in china

Ketoconazole in stock

Cas:65277-42-1

Min.Order:25 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

Our Adwantage: 1.We have stock so we can delivery quickly at the very day when receive the payment. 2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order. 3.High quality gua

Synthetic route

1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanone
46503-52-0

1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanone

(+/-)-1-acetyl-4-<4-(2,3-dihydroxypropoxy)phenyl>piperazine

(+/-)-1-acetyl-4-<4-(2,3-dihydroxypropoxy)phenyl>piperazine

ketoconazole
65277-42-1

ketoconazole

Conditions
ConditionsYield
With trifluoroacetic acid In dimethyl sulfoxide; toluene for 16h; Reagent/catalyst; Temperature; Reflux;80%
1H-imidazole
288-32-4

1H-imidazole

(2R,4S)-cis-2-(bromomethyl)-2-(2,4-dichlorophenyl)-4-<<4-(4-acetylpiperazin-1-yl)phenoxy>methyl>-1,3-dioxolane
142128-67-4

(2R,4S)-cis-2-(bromomethyl)-2-(2,4-dichlorophenyl)-4-<<4-(4-acetylpiperazin-1-yl)phenoxy>methyl>-1,3-dioxolane

A

ketoconazole
65277-42-1

ketoconazole

B

(2R,4S)-cis-2-(hydroxymethyl)-2-(2,4-dichlorophenyl)-4-<<4-(4-acetylpiperazin-1-yl)phenoxy>methyl>-1,3-dioxolane
142004-25-9

(2R,4S)-cis-2-(hydroxymethyl)-2-(2,4-dichlorophenyl)-4-<<4-(4-acetylpiperazin-1-yl)phenoxy>methyl>-1,3-dioxolane

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl acetamide for 4h; Heating;A 53%
B 10%
(2R,4R)-(+)-<2-(2,4-dichlorophenyl)-2-<(1H-imidazol-1-yl)methyl>-1,3-dioxolan-4-yl>methyl methanesulfonate
170210-43-2

(2R,4R)-(+)-<2-(2,4-dichlorophenyl)-2-<(1H-imidazol-1-yl)methyl>-1,3-dioxolan-4-yl>methyl methanesulfonate

N-acetyl-N'-(4-hydroxyphenyl)piperazine
67914-60-7, 89929-31-7

N-acetyl-N'-(4-hydroxyphenyl)piperazine

ketoconazole
65277-42-1

ketoconazole

Conditions
ConditionsYield
With sodium hydride 1.) DMSO, RT, 1 h, 2.) DMSO, 80 deg C, 4 h; Yield given. Multistep reaction;
[cis-[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl] 4-methyl-benzenesulfonate

[cis-[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl] 4-methyl-benzenesulfonate

N-acetyl-N'-(4-hydroxyphenyl)piperazine
67914-60-7, 89929-31-7

N-acetyl-N'-(4-hydroxyphenyl)piperazine

ketoconazole
65277-42-1

ketoconazole

Conditions
ConditionsYield
With sodium hydride In dimethyl sulfoxide at 0 - 80℃;
1-(4-hydroxyphenyl)piperazine
56621-48-8

1-(4-hydroxyphenyl)piperazine

ketoconazole
65277-42-1

ketoconazole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: pyridine / CH2Cl2
2: K2CO3 / methanol / 20 °C
3: NaH / dimethylsulfoxide / 0 - 80 °C
View Scheme
1-(4-Acetoxyphenyl)-4-acetylpiperazine
133345-21-8

1-(4-Acetoxyphenyl)-4-acetylpiperazine

ketoconazole
65277-42-1

ketoconazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: K2CO3 / methanol / 20 °C
2: NaH / dimethylsulfoxide / 0 - 80 °C
View Scheme
(2R,4R)-(+)-<2-(2,4-dichlorophenyl)-2-<(1H-imidazol-1-yl)methyl>-1,3-dioxolan-4-yl>methyl benzoate
70894-66-5, 134071-29-7, 138866-89-4

(2R,4R)-(+)-<2-(2,4-dichlorophenyl)-2-<(1H-imidazol-1-yl)methyl>-1,3-dioxolan-4-yl>methyl benzoate

ketoconazole
65277-42-1

ketoconazole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: NaOH / dioxane / Heating
2: pyridine
3: NaH / dimethylsulfoxide / 0 - 80 °C
View Scheme
(2R,4S)-(+)-2-(2,4-dichlorophenyl)-2-<(1H-imidazol-1-yl)methyl>-1,3-dioxolane-4-methanol
170210-42-1

(2R,4S)-(+)-2-(2,4-dichlorophenyl)-2-<(1H-imidazol-1-yl)methyl>-1,3-dioxolane-4-methanol

ketoconazole
65277-42-1

ketoconazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: pyridine
2: NaH / dimethylsulfoxide / 0 - 80 °C
View Scheme
Multi-step reaction with 2 steps
1: 81 percent / pyridine / 16 h / 0 °C
2: 1.) NaH / 1.) DMSO, RT, 1 h, 2.) DMSO, 80 deg C, 4 h
View Scheme
(2R,4R)-(+)-<2-(2,4-dichlorophenyl)-2-<(1H-imidazol-1-yl)methyl>-1,3-dioxolan-4-yl>methyl benzoate nitrate

(2R,4R)-(+)-<2-(2,4-dichlorophenyl)-2-<(1H-imidazol-1-yl)methyl>-1,3-dioxolan-4-yl>methyl benzoate nitrate

ketoconazole
65277-42-1

ketoconazole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 89 percent / 50percent aq. NaOH / dioxane / 0.5 h / Heating
2: 81 percent / pyridine / 16 h / 0 °C
3: 1.) NaH / 1.) DMSO, RT, 1 h, 2.) DMSO, 80 deg C, 4 h
View Scheme
1-(4-{4-[2-(2,4-dichloro-phenyl)-2-imidazol-1-ylmethyl-[1,3]dioxolan-4-ylmethoxy]-phenyl}-piperazin-1-yl)-ethanone
79156-75-5

1-(4-{4-[2-(2,4-dichloro-phenyl)-2-imidazol-1-ylmethyl-[1,3]dioxolan-4-ylmethoxy]-phenyl}-piperazin-1-yl)-ethanone

A

ketoconazole
65277-42-1

ketoconazole

B

(2R,4R)-Ketoconazole
142128-58-3

(2R,4R)-Ketoconazole

D

(2S,4S)-Ketoconazole
142128-60-7

(2S,4S)-Ketoconazole

Conditions
ConditionsYield
With methanol; sodium dodecyl-sulfate; 2,3,6-trimethyl-beta-cyclodextrin; sodium hydroxide In aq. phosphate buffer at 25℃; pH=2.5; pH-value; Reagent/catalyst; Temperature; Resolution of racemate;
Conditions
ConditionsYield
With Beckman P/ACE MDQ Capillary Electrophoresis System equipped fused-silica capillaries (Polymicro Technologies, Phoenix, Arizona) of 50-μm ID cut with sulfobutyl ether β-cyclodextrin as chiral selector In aq. buffer at 25℃; pH=2.5; Concentration; pH-value; Reagent/catalyst; Resolution of racemate;
N-acetyl-N'-(4-hydroxyphenyl)piperazine
67914-60-7, 89929-31-7

N-acetyl-N'-(4-hydroxyphenyl)piperazine

ketoconazole
65277-42-1

ketoconazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hydroxide; tetrabutylammomium bromide / water; toluene / 16 h / 25 °C
2: trifluoroacetic acid / toluene; dimethyl sulfoxide / 16 h / Reflux
View Scheme
1,3-Dichlorobenzene
541-73-1

1,3-Dichlorobenzene

ketoconazole
65277-42-1

ketoconazole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: aluminum (III) chloride / dichloromethane / 0.5 h / 25 °C
1.2: 16 h / Reflux
2.1: triethylamine / dichloromethane / 10 °C
3.1: trifluoroacetic acid / toluene; dimethyl sulfoxide / 16 h / Reflux
View Scheme
Multi-step reaction with 3 steps
1.1: aluminum (III) chloride / dichloromethane / 0.5 h / 25 °C
1.2: 16 h / Reflux
2.1: triethylamine / dichloromethane / 10 °C
3.1: trifluoroacetic acid / toluene; dimethyl sulfoxide / 16 h / Reflux
View Scheme
2,4-dichlorophenacyl bromide
2631-72-3

2,4-dichlorophenacyl bromide

ketoconazole
65277-42-1

ketoconazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: triethylamine / dichloromethane / 10 °C
2: trifluoroacetic acid / toluene; dimethyl sulfoxide / 16 h / Reflux
View Scheme
Conditions
ConditionsYield
With cellulose (3,5-dimethylphenylcarbamate) coated reduced graphene oxide(at)silica gel In hexane at 25℃; Resolution of racemate; enantioselective reaction;
copper(II) acetate monohydrate
6046-93-1

copper(II) acetate monohydrate

ketoconazole
65277-42-1

ketoconazole

[Cu(ketoconazole)2(Ac)2]*H2O

[Cu(ketoconazole)2(Ac)2]*H2O

Conditions
ConditionsYield
In methanol at 25℃; for 24h;94%
copper(II) nitrate trihydrate

copper(II) nitrate trihydrate

ketoconazole
65277-42-1

ketoconazole

[Cu(ketoconazole)2(NO3)(H2O)](NO3)*H2O

[Cu(ketoconazole)2(NO3)(H2O)](NO3)*H2O

Conditions
ConditionsYield
In methanol at 25℃; for 36h;89%
zinc(II) nitrate hexahydrate

zinc(II) nitrate hexahydrate

ketoconazole
65277-42-1

ketoconazole

[Zn(ketoconazole)2(NO3)(H2O)](NO3)

[Zn(ketoconazole)2(NO3)(H2O)](NO3)

Conditions
ConditionsYield
In methanol at 25℃; for 24h;86%
bis(triphenylphosphino)copper(I) nitrate
14494-93-0, 23751-62-4, 106678-35-7

bis(triphenylphosphino)copper(I) nitrate

ketoconazole
65277-42-1

ketoconazole

[Cu(PPh3)2(cis-1-acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine)2]NO3

[Cu(PPh3)2(cis-1-acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine)2]NO3

Conditions
ConditionsYield
In acetonitrile for 24h;83%
potassium tetrachloroplatinate(II)
10025-99-7

potassium tetrachloroplatinate(II)

ketoconazole
65277-42-1

ketoconazole

trans-Pt(cis-1-acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine)2Cl2

trans-Pt(cis-1-acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine)2Cl2

Conditions
ConditionsYield
In ethanol; water at 100℃; for 2h;78%
methanol
67-56-1

methanol

ketoconazole
65277-42-1

ketoconazole

zinc(II) chloride
7646-85-7

zinc(II) chloride

[Zn(ketoconazole)2Cl2]*0.4CH3OH

[Zn(ketoconazole)2Cl2]*0.4CH3OH

Conditions
ConditionsYield
at 25℃; for 24h;78%
(tetrahydrothiophene)gold(I) chloride
39929-21-0

(tetrahydrothiophene)gold(I) chloride

ketoconazole
65277-42-1

ketoconazole

[Au(cis-1-acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine)2]Cl

[Au(cis-1-acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine)2]Cl

Conditions
ConditionsYield
In dichloromethane at 0℃; for 2h;65%
zinc(II) acetate dihydrate
5970-45-6

zinc(II) acetate dihydrate

ketoconazole
65277-42-1

ketoconazole

[Zn(ketoconazole)2(Ac)2]*H2O

[Zn(ketoconazole)2(Ac)2]*H2O

Conditions
ConditionsYield
In methanol at 25℃; for 24h;65%
Ethyl bromodifluoroacetate
667-27-6

Ethyl bromodifluoroacetate

ketoconazole
65277-42-1

ketoconazole

1-(4-(4-(((2R,4S)-2-(2,4-dichlorophenyl)-2-((3-(difluoromethyl)-2-thioxo-2,3-dihydro-1H-imidazol-1-yl)methyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)ethan-1-one

1-(4-(4-(((2R,4S)-2-(2,4-dichlorophenyl)-2-((3-(difluoromethyl)-2-thioxo-2,3-dihydro-1H-imidazol-1-yl)methyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)ethan-1-one

Conditions
ConditionsYield
With rongalite; sulfur In N,N-dimethyl acetamide at 100℃; for 24h; Sealed tube;43%
With sulfur; rongalite In N,N-dimethyl acetamide at 100℃; for 24h; Sealed tube;43%
ketoconazole
65277-42-1

ketoconazole

copper dichloride

copper dichloride

[Cu(ketoconazole)2Cl2]*3.2H2O

[Cu(ketoconazole)2Cl2]*3.2H2O

Conditions
ConditionsYield
In methanol at 25℃; for 0.5h;38%
ethyl bromofluoroacetate
401-55-8

ethyl bromofluoroacetate

ketoconazole
65277-42-1

ketoconazole

2-(3-(((2R,4S)-4-((4-(4-acetylpiperazin-1-yl)phenoxy)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-2-yl)methyl)-2-thioxo-2,3-dihydro-1H-imidazol-1-yl)-2-fluoroacetic acid ethyl ester

2-(3-(((2R,4S)-4-((4-(4-acetylpiperazin-1-yl)phenoxy)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-2-yl)methyl)-2-thioxo-2,3-dihydro-1H-imidazol-1-yl)-2-fluoroacetic acid ethyl ester

Conditions
ConditionsYield
With sulfur; sodium dithionite In 1,2-dichloro-ethane at 80℃; for 24h; Sealed tube;37%
With sulfur; sodium dithionite In 1,2-dichloro-ethane at 100℃; for 24h; Sealed tube;37%
ketoconazole
65277-42-1

ketoconazole

(+/-)-Deacylketoconazole

(+/-)-Deacylketoconazole

Conditions
ConditionsYield
With potassium hydroxide In isopropyl alcohol
With sodium hydroxide In methanol Reflux;700 mg
ketoconazole
65277-42-1

ketoconazole

ketoconazole-iodine

ketoconazole-iodine

Conditions
ConditionsYield
With iodine In 1,4-dioxane at 24.84 - 39.84℃; Kinetics; Equilibrium constant; Thermodynamic data; Solvent;
ketoconazole
65277-42-1

ketoconazole

2,4-diamino-6-piperidinopyrimidine 3-oxide
38304-91-5

2,4-diamino-6-piperidinopyrimidine 3-oxide

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