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Sunmore Healthcare Co., LTD.

Time Efficiency, Cost Effectiveness, Better Possibilities! 1. Better Quality & Competetive Price. 2. Quick & Professional Quotation. 3. Over Three Decades of Experience in This F

Erythromycin

Cas:114-07-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Dawn Ray Pharmaceutical Co.,Ltd

It conforms to USP.We have GMP for this mterial. Appearance:White crystalline powder Storage:room temperature Package:25kg/drum or customer requirements Application:medicine additives , functional food additives,cosmetic additives etc. Transportati

Erythromycin base

Cas:114-07-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

99% up GMP DMF Erythromycin Thiocyanate 114-07-8

Cas:114-07-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay (Ursolic acid) 98%min 98.22% -----------------------------------------------------------------------------------------------------------

High purity 114-07-8 Erythromycin

Cas:114-07-8

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Trading Company

inquiry

Kono Chem Co.,Ltd

We are an independent, privately owned company comprised of a dedicated team of professionals with a singular purpose: your success. To us, you are not a project and you’re not only a client. You are our strategic partner. We know our success

Erythromycin

Cas:114-07-8

Min.Order:1 Gram

FOB Price: $650.0 / 1000.0

Type:Other

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages for Erythromycin Cas 114-07-8 Guaranteed the purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White crystalline powder Storage:0-6°C Package:1kg/foil bag, 25kg/dru

Wholesale factory low price Erythromycin Cas 114-07-8 with best purity

Cas:114-07-8

Min.Order:1 Kilogram

FOB Price: $98.0

Type:Trading Company

inquiry

Xi'an Quanao Biotech Co., Ltd.

Xi’an Quanao Biotech Co., Ltd. with 18 years experience in plant extract filed. Product grade: Medicine, Health care product, Cosmetics, Food, Beverage, Feed. Hot selling market: Europe, North America, South America, Middle East, Asia Pacifi

Top quality 99% Erythromycin powder CAS:114-07-8

Cas:114-07-8

Min.Order:1 Kilogram

FOB Price: $36.0 / 66.0

Type:Manufacturers

inquiry

Hangzhou Think Chemical Co. Ltd

Erythromycin CAS No.:114-07-8 Name: Erythromycin Synonyms: (-)-Erythromycin Molecular Structure Molecular Formula: C37H67NO13 Molecular Weight: 733.93

High purity Erythromycin CAS No.:114-07-8

Cas:114-07-8

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Other

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Erythromycin

Cas:114-07-8

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Erythromycin 114-07-8 ISO Producer

Cas:114-07-8

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chengdu Lemeitian Pharmaceutical Technology Co,. Ltd

ADVANTAGE: 1. More than 3,000 Chinese medicine reference substances / standard products available from stock, issued on the same day, multiple cities can be delivered the next day 2. The products are provided with COA, HPLC, NMR, quality assurance,

Erythromycin

Cas:114-07-8

Min.Order:10 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price in China. If you are looking for the product’s supplier in China, DayangChem is your best choice. As a leading manufacturer and supplier of chemicals in China, Day

Erythromycin

Cas:114-07-8

Min.Order:1 Kilogram

FOB Price: $4.0

Type:Lab/Research institutions

inquiry

Hubei DiBo chemical co., LTD

Name:Erythromycin CAS NO: 114-07-8 Grade:Medical scientific research and export Molecular formula:C37H67NO13 Molecular weight: 733.93 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Dat

Erythromycin/ CAS:114-07-8/ raw material/ high-quality

Cas:114-07-8

Min.Order:25 Kilogram

FOB Price: $2.0 / 3.0

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

Erythromycin Basic information Product Name: Erythromycin Synonyms: abboticin;abomacetin;dotycin;em;emu;e-mycin;erycin;erycinum CAS: 114-07-8 MF:

TIANFU-CHEM CAS:114-07-8 Erythromycin

Cas:114-07-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

Erythromycin

Cas:114-07-8

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 114-07-8 with best quality

Cas:114-07-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Erythromycin/ LIDE PHARMA- Factory supply / Best price

Cas:114-07-8

Min.Order:25 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

Erythromycin CAS114-07-8

Cas:114-07-8

Min.Order:1 Kilogram

FOB Price: $289.0 / 499.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Name: Erythromycin Synonyms: Abomacetin CAS:114-07-8 MF: C37H67NO13 Appearance: white powder Storage:Store in cool and dry place, away from sun light. Package: 25kgs/drum Application:APIs Transportation:By sea or by air Port:Qingdao port

Erythromycin CAS:114-07-8

Cas:114-07-8

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:white powder Storage:Store in sealed containers at cool & d

USP 85% Erythromycin CAS 114-07-8 Hot Sale Pharmaceutical Raw Materials

Cas:114-07-8

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1,In No Less five years exporting experience. 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Onchem specialized in APIs, chemical intermediate

High quality Erythromycin99% with low price

Cas:114-07-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Baoji Guokang Healthchem co.,ltd

Erythromycin is white or almost white crystalline or powder;Odorless, bitter taste; slight moist.In methanol, ethanol or acetone soluble,Very slightly soluble in water. Erythromycin can affect the protein synthesis, general bacteria to gram-

Antibiotic,Erythromycin,cas:114-07-8

Cas:114-07-8

Min.Order:1 Kilogram

FOB Price: $140.0 / 150.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Erythromycin CAS:114-07-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,

Erythromycin CAS:114-07-8

Cas:114-07-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Terui OP New Material Technology Co., Ltd.

We have overseas warehouses in California, New Laredo Mexico, Vancouver Canada, Amsterdam Netherlands, and Melbourne Australia. Overseas warehouses can provide some of the best-selling products. We look forward to the cooperation of local powerful

Chinese suppliers CAS 114-07-8 Erythromycin

Cas:114-07-8

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Erythromycin

Cas:114-07-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Mojin Biotechnology Co.,Ltd

Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in chemical raw materials and chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe,

High Purity China Factory Price Erythromycin Powder CAS 114-07-8

Cas:114-07-8

Min.Order:1 Kilogram

FOB Price: $70.0 / 100.0

Type:Trading Company

inquiry

Lonwin Chemical Group Limited

EP Standard API CAS: 114-07-8 Specificatio Items Specification Result Assay 93.0% ~102.0% 98.0% Appearance

Factory supply EP Standard API

Cas:114-07-8

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. 3) OEM/ODM Available;

Erythromycin CAS 114-07-8

Cas:114-07-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Erythromycin

Cas:114-07-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

erythromycin A thiocyanate
7704-67-8

erythromycin A thiocyanate

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
With sodium hydroxide In methanol at 40℃; pH=9-9.8;99.33%
With ammonia In dichloromethane; water at 25 - 35℃;
In dichloromethane; water at 37℃; pH=12; Product distribution / selectivity;
With ammonia In water at 35 - 70℃; for 1.5h; Reagent/catalyst;106 g
erythromycin A N-oxide
992-65-4

erythromycin A N-oxide

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
With hydrogen; Raney-Ni (W4) In ethanol at 25℃; for 1h;84%
With hydrogen; Rany Ni (W4) In ethanol at 25℃; for 1h;84%
(2',4''-O-bistrimethylsilyl)-6-O-methylerythromycinA-9[O-(1-ethoxy-1-methylethyl)]oxime
119665-62-2

(2',4''-O-bistrimethylsilyl)-6-O-methylerythromycinA-9[O-(1-ethoxy-1-methylethyl)]oxime

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
With formic acid; water; sodium hydrogensulfite In ethanol for 8h; Heating;66.7%
formaldehyd
50-00-0

formaldehyd

N-Demethylerythromycin A
992-62-1

N-Demethylerythromycin A

A

C38H66N2O13

C38H66N2O13

B

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
With sodium cyanoborohydride In methanol; water for 0.5h; Ambient temperature;A 11.4%
B n/a
formaldehyd
50-00-0

formaldehyd

N-Demethylerythromycin A
992-62-1

N-Demethylerythromycin A

NaCNBH3

NaCNBH3

A

C38H66N2O13

C38H66N2O13

B

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
In methanol; water for 0.5h; Ambient temperature;A 11.4%
B n/a
9-deoxo-9-iminoerythromycin A
30760-16-8

9-deoxo-9-iminoerythromycin A

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
With water at 5℃; Yield given;
With water In methanol at 23℃; pH 7, methanol-phosphate buffer, various pH, other erythromycin;
With hydrogenchloride; water In ethanol pH=5 - 6;
9-N,11-O-benzylidene-9-deoxo-9-iminoerythromycin A
123943-98-6

9-N,11-O-benzylidene-9-deoxo-9-iminoerythromycin A

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
With water at 37℃; Rate constant; pH 7 (1:1 methanol-phosphate buffer);
C45H74N2O12
123944-04-7

C45H74N2O12

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
With water at 37℃; Rate constant; pH 7 (1:1 methanol-phosphate buffer);
C44H71ClN2O12
123944-06-9

C44H71ClN2O12

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
With water at 37℃; Rate constant; pH 7 (1:1 methanol-phosphate buffer);
C45H74N2O13
123944-10-5

C45H74N2O13

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
With water at 37℃; Rate constant; pH 7 (1:1 methanol-phosphate buffer);
C44H71N3O14
123944-09-2

C44H71N3O14

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
With water at 37℃; Rate constant; pH 7 (1:1 methanol-phosphate buffer);
erythromycin A 9-(E)-oxime
111321-02-9

erythromycin A 9-(E)-oxime

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 30 percent / Bu3P / tetrahydrofuran / 1 h / 0 °C
2: H2O; HCl / ethanol / pH 5 - 6
View Scheme
Multi-step reaction with 2 steps
1.1: PySeSePy; Me3P / tetrahydrofuran / 0.17 h / 0 °C
1.2: 80 percent / H2O / pH 10
2.1: H2O; HCl / ethanol / pH 5 - 6
View Scheme
9-deoxy-9-homoerythromycin A(Z) oxime

9-deoxy-9-homoerythromycin A(Z) oxime

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Bu3P / tetrahydrofuran / 1 h / 0 °C
2: H2O; HCl / ethanol / pH 5 - 6
View Scheme
9S-Dihydroerythronolide A aglycon
15562-19-3, 28316-68-9

9S-Dihydroerythronolide A aglycon

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
Multi-step reaction with 11 steps
1: 87 percent / DL-10-camphorsulfonic acid / CH2Cl2 / 72 h / -30 °C
2: 100 percent / pyridinium p-toluenesulfonate / CH2Cl2 / 1.5 h / 25 °C
3: 95 percent / H2 / Pd(OH)2/C / ethyl acetate / 2 h / 25 °C
4: 63 percent / silver triflate, 4A molecular sieves / CH2Cl2; toluene / 4 h / 25 °C
5: 100 percent / m-chloroperoxybenzoic acid / CH2Cl2 / 0.25 h / 25 °C
6: 90 percent / 4A molecular sieves, N-iodosuccinimide, TfOH / CH2Cl2 / 0.17 h / -35 °C
7: 66 percent / 50percent aq. AcOH / 12 h / 40 °C
8: 54 percent / H2 / Raney Ni (W4) / ethanol / 1.5 h / 40 °C
9: 99 percent / m-chloroperoxybenzoic acid / CH2Cl2 / 0.17 h / 25 °C
10: 58 percent / bis(tri-n-butyltin) oxide, Br2 / CH2Cl2 / 24 h / 25 °C
11: 84 percent / H2 / Rany Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
Multi-step reaction with 11 steps
1: 87 percent / CSA / CH2Cl2 / 72 h / -30 °C
2: PPTS / CH2Cl2 / 1.5 h / 25 °C
3: H2 / Pd(OH)2 / 2 h / 25 °C
4: 63 percent / AgOTf, MS 4A / CH2Cl2; toluene / 4 h / 0 - 25 °C
5: 99 percent / mCPBA / CHCl3 / 0.33 h / 25 °C
6: 90 percent / NIS, TfOH, MS 4A / CH2Cl2 / 0.17 h / -35 °C
7: 66 percent / 50percent aq. AcOH / 24 h / 40 °C
8: 54 percent / H2 / Raney-Ni (W4) / ethanol
9: 99 percent / mCPBA / CHCl3 / 0.17 h / 25 °C
10: 58 percent / (n-Bu3Sn)2O, Br2 / CH2Cl2 / 24 h / 25 °C
11: 84 percent / H2 / Raney-Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
(9S)-9-dihydro-9,11-O-isopropylideneerythronolide A
138505-34-7

(9S)-9-dihydro-9,11-O-isopropylideneerythronolide A

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1: 63 percent / silver triflate, 4A molecular sieves / CH2Cl2; toluene / 4 h / 25 °C
2: 100 percent / m-chloroperoxybenzoic acid / CH2Cl2 / 0.25 h / 25 °C
3: 90 percent / 4A molecular sieves, N-iodosuccinimide, TfOH / CH2Cl2 / 0.17 h / -35 °C
4: 66 percent / 50percent aq. AcOH / 12 h / 40 °C
5: 54 percent / H2 / Raney Ni (W4) / ethanol / 1.5 h / 40 °C
6: 99 percent / m-chloroperoxybenzoic acid / CH2Cl2 / 0.17 h / 25 °C
7: 58 percent / bis(tri-n-butyltin) oxide, Br2 / CH2Cl2 / 24 h / 25 °C
8: 84 percent / H2 / Rany Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
Multi-step reaction with 8 steps
1: 63 percent / AgOTf, MS 4A / CH2Cl2; toluene / 4 h / 0 - 25 °C
2: 99 percent / mCPBA / CHCl3 / 0.33 h / 25 °C
3: 90 percent / NIS, TfOH, MS 4A / CH2Cl2 / 0.17 h / -35 °C
4: 66 percent / 50percent aq. AcOH / 24 h / 40 °C
5: 54 percent / H2 / Raney-Ni (W4) / ethanol
6: 99 percent / mCPBA / CHCl3 / 0.17 h / 25 °C
7: 58 percent / (n-Bu3Sn)2O, Br2 / CH2Cl2 / 24 h / 25 °C
8: 84 percent / H2 / Raney-Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
(9S)-9-dihydro-3,5-O-(p-methoxybenzylidene)erythronolide A
138505-32-5

(9S)-9-dihydro-3,5-O-(p-methoxybenzylidene)erythronolide A

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
Multi-step reaction with 10 steps
1: 100 percent / pyridinium p-toluenesulfonate / CH2Cl2 / 1.5 h / 25 °C
2: 95 percent / H2 / Pd(OH)2/C / ethyl acetate / 2 h / 25 °C
3: 63 percent / silver triflate, 4A molecular sieves / CH2Cl2; toluene / 4 h / 25 °C
4: 100 percent / m-chloroperoxybenzoic acid / CH2Cl2 / 0.25 h / 25 °C
5: 90 percent / 4A molecular sieves, N-iodosuccinimide, TfOH / CH2Cl2 / 0.17 h / -35 °C
6: 66 percent / 50percent aq. AcOH / 12 h / 40 °C
7: 54 percent / H2 / Raney Ni (W4) / ethanol / 1.5 h / 40 °C
8: 99 percent / m-chloroperoxybenzoic acid / CH2Cl2 / 0.17 h / 25 °C
9: 58 percent / bis(tri-n-butyltin) oxide, Br2 / CH2Cl2 / 24 h / 25 °C
10: 84 percent / H2 / Rany Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
Multi-step reaction with 10 steps
1: PPTS / CH2Cl2 / 1.5 h / 25 °C
2: H2 / Pd(OH)2 / 2 h / 25 °C
3: 63 percent / AgOTf, MS 4A / CH2Cl2; toluene / 4 h / 0 - 25 °C
4: 99 percent / mCPBA / CHCl3 / 0.33 h / 25 °C
5: 90 percent / NIS, TfOH, MS 4A / CH2Cl2 / 0.17 h / -35 °C
6: 66 percent / 50percent aq. AcOH / 24 h / 40 °C
7: 54 percent / H2 / Raney-Ni (W4) / ethanol
8: 99 percent / mCPBA / CHCl3 / 0.17 h / 25 °C
9: 58 percent / (n-Bu3Sn)2O, Br2 / CH2Cl2 / 24 h / 25 °C
10: 84 percent / H2 / Raney-Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
(9S)-9-dihydro-9,11-O-isopropylidene-3,5-O-(p-methoxybenzylidene)erythronolide
138505-33-6

(9S)-9-dihydro-9,11-O-isopropylidene-3,5-O-(p-methoxybenzylidene)erythronolide

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
Multi-step reaction with 9 steps
1: 95 percent / H2 / Pd(OH)2/C / ethyl acetate / 2 h / 25 °C
2: 63 percent / silver triflate, 4A molecular sieves / CH2Cl2; toluene / 4 h / 25 °C
3: 100 percent / m-chloroperoxybenzoic acid / CH2Cl2 / 0.25 h / 25 °C
4: 90 percent / 4A molecular sieves, N-iodosuccinimide, TfOH / CH2Cl2 / 0.17 h / -35 °C
5: 66 percent / 50percent aq. AcOH / 12 h / 40 °C
6: 54 percent / H2 / Raney Ni (W4) / ethanol / 1.5 h / 40 °C
7: 99 percent / m-chloroperoxybenzoic acid / CH2Cl2 / 0.17 h / 25 °C
8: 58 percent / bis(tri-n-butyltin) oxide, Br2 / CH2Cl2 / 24 h / 25 °C
9: 84 percent / H2 / Rany Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
Multi-step reaction with 9 steps
1: H2 / Pd(OH)2 / 2 h / 25 °C
2: 63 percent / AgOTf, MS 4A / CH2Cl2; toluene / 4 h / 0 - 25 °C
3: 99 percent / mCPBA / CHCl3 / 0.33 h / 25 °C
4: 90 percent / NIS, TfOH, MS 4A / CH2Cl2 / 0.17 h / -35 °C
5: 66 percent / 50percent aq. AcOH / 24 h / 40 °C
6: 54 percent / H2 / Raney-Ni (W4) / ethanol
7: 99 percent / mCPBA / CHCl3 / 0.17 h / 25 °C
8: 58 percent / (n-Bu3Sn)2O, Br2 / CH2Cl2 / 24 h / 25 °C
9: 84 percent / H2 / Raney-Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
(9S)-9-dihydro-9,11-O-isopropylidene-5-O-(2-O-(methoxycarbonyl)-β-D-desosaminyl)erythronolide
138505-35-8

(9S)-9-dihydro-9,11-O-isopropylidene-5-O-(2-O-(methoxycarbonyl)-β-D-desosaminyl)erythronolide

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: 100 percent / m-chloroperoxybenzoic acid / CH2Cl2 / 0.25 h / 25 °C
2: 90 percent / 4A molecular sieves, N-iodosuccinimide, TfOH / CH2Cl2 / 0.17 h / -35 °C
3: 66 percent / 50percent aq. AcOH / 12 h / 40 °C
4: 54 percent / H2 / Raney Ni (W4) / ethanol / 1.5 h / 40 °C
5: 99 percent / m-chloroperoxybenzoic acid / CH2Cl2 / 0.17 h / 25 °C
6: 58 percent / bis(tri-n-butyltin) oxide, Br2 / CH2Cl2 / 24 h / 25 °C
7: 84 percent / H2 / Rany Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
Multi-step reaction with 7 steps
1: 99 percent / mCPBA / CHCl3 / 0.33 h / 25 °C
2: 90 percent / NIS, TfOH, MS 4A / CH2Cl2 / 0.17 h / -35 °C
3: 66 percent / 50percent aq. AcOH / 24 h / 40 °C
4: 54 percent / H2 / Raney-Ni (W4) / ethanol
5: 99 percent / mCPBA / CHCl3 / 0.17 h / 25 °C
6: 58 percent / (n-Bu3Sn)2O, Br2 / CH2Cl2 / 24 h / 25 °C
7: 84 percent / H2 / Raney-Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
(9S)-9-dihydro-9,11-O-isopropylidene-5-O-(2-O-(methoxycarbonyl)-β-D-desosaminyl)erythronolide A N-oxide
138505-36-9

(9S)-9-dihydro-9,11-O-isopropylidene-5-O-(2-O-(methoxycarbonyl)-β-D-desosaminyl)erythronolide A N-oxide

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 90 percent / 4A molecular sieves, N-iodosuccinimide, TfOH / CH2Cl2 / 0.17 h / -35 °C
2: 66 percent / 50percent aq. AcOH / 12 h / 40 °C
3: 54 percent / H2 / Raney Ni (W4) / ethanol / 1.5 h / 40 °C
4: 99 percent / m-chloroperoxybenzoic acid / CH2Cl2 / 0.17 h / 25 °C
5: 58 percent / bis(tri-n-butyltin) oxide, Br2 / CH2Cl2 / 24 h / 25 °C
6: 84 percent / H2 / Rany Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
Multi-step reaction with 6 steps
1: 90 percent / NIS, TfOH, MS 4A / CH2Cl2 / 0.17 h / -35 °C
2: 66 percent / 50percent aq. AcOH / 24 h / 40 °C
3: 54 percent / H2 / Raney-Ni (W4) / ethanol
4: 99 percent / mCPBA / CHCl3 / 0.17 h / 25 °C
5: 58 percent / (n-Bu3Sn)2O, Br2 / CH2Cl2 / 24 h / 25 °C
6: 84 percent / H2 / Raney-Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
(9S)-9-dihydroerythromycin A N-oxide
138505-44-9

(9S)-9-dihydroerythromycin A N-oxide

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 58 percent / bis(tri-n-butyltin) oxide, Br2 / CH2Cl2 / 24 h / 25 °C
2: 84 percent / H2 / Rany Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
Multi-step reaction with 2 steps
1: 58 percent / (n-Bu3Sn)2O, Br2 / CH2Cl2 / 24 h / 25 °C
2: 84 percent / H2 / Raney-Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
(9S)-3-O-(2,6-anhydro-4-O-benzyl-3-C-methyl-3-O-methyl-2-thio-α-L-altropyranosyl)-9-dihydro-5-O-(2-O-(methoxycarbonyl)-β-D-desosaminyl)erythronolide A N-Oxide
138505-43-8

(9S)-3-O-(2,6-anhydro-4-O-benzyl-3-C-methyl-3-O-methyl-2-thio-α-L-altropyranosyl)-9-dihydro-5-O-(2-O-(methoxycarbonyl)-β-D-desosaminyl)erythronolide A N-Oxide

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 54 percent / H2 / Raney Ni (W4) / ethanol / 1.5 h / 40 °C
2: 99 percent / m-chloroperoxybenzoic acid / CH2Cl2 / 0.17 h / 25 °C
3: 58 percent / bis(tri-n-butyltin) oxide, Br2 / CH2Cl2 / 24 h / 25 °C
4: 84 percent / H2 / Rany Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
Multi-step reaction with 4 steps
1: 54 percent / H2 / Raney-Ni (W4) / ethanol
2: 99 percent / mCPBA / CHCl3 / 0.17 h / 25 °C
3: 58 percent / (n-Bu3Sn)2O, Br2 / CH2Cl2 / 24 h / 25 °C
4: 84 percent / H2 / Raney-Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
(9S)-3-O-(2,6-anhydro-4-O-benzyl-3-C-methyl-3-O-methyl-2-thio-α-L-altropyranosyl)-9-dihydro-9,11-O-isopropylidene-5-O-(2-O-(methoxycarbonyl)-β-D-desosaminyl)erythronolide A N-Oxide
138505-42-7

(9S)-3-O-(2,6-anhydro-4-O-benzyl-3-C-methyl-3-O-methyl-2-thio-α-L-altropyranosyl)-9-dihydro-9,11-O-isopropylidene-5-O-(2-O-(methoxycarbonyl)-β-D-desosaminyl)erythronolide A N-Oxide

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 66 percent / 50percent aq. AcOH / 12 h / 40 °C
2: 54 percent / H2 / Raney Ni (W4) / ethanol / 1.5 h / 40 °C
3: 99 percent / m-chloroperoxybenzoic acid / CH2Cl2 / 0.17 h / 25 °C
4: 58 percent / bis(tri-n-butyltin) oxide, Br2 / CH2Cl2 / 24 h / 25 °C
5: 84 percent / H2 / Rany Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
Multi-step reaction with 5 steps
1: 66 percent / 50percent aq. AcOH / 24 h / 40 °C
2: 54 percent / H2 / Raney-Ni (W4) / ethanol
3: 99 percent / mCPBA / CHCl3 / 0.17 h / 25 °C
4: 58 percent / (n-Bu3Sn)2O, Br2 / CH2Cl2 / 24 h / 25 °C
5: 84 percent / H2 / Raney-Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
methyl 2,6-anhydro-4-O-benzyl-3-C-methyl-3-O-methyl-2-thio-α-L-altropyranoside
137101-04-3

methyl 2,6-anhydro-4-O-benzyl-3-C-methyl-3-O-methyl-2-thio-α-L-altropyranoside

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: 91 percent / TMSOTf / CH2Cl2 / 0.25 h / 0 °C
2: 90 percent / 4A molecular sieves, N-iodosuccinimide, TfOH / CH2Cl2 / 0.17 h / -35 °C
3: 66 percent / 50percent aq. AcOH / 12 h / 40 °C
4: 54 percent / H2 / Raney Ni (W4) / ethanol / 1.5 h / 40 °C
5: 99 percent / m-chloroperoxybenzoic acid / CH2Cl2 / 0.17 h / 25 °C
6: 58 percent / bis(tri-n-butyltin) oxide, Br2 / CH2Cl2 / 24 h / 25 °C
7: 84 percent / H2 / Rany Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
Multi-step reaction with 7 steps
1: 96 percent / TMSOTf / CH2Cl2 / 0.17 h / -10 °C
2: 90 percent / NIS, TfOH, MS 4A / CH2Cl2 / 0.17 h / -35 °C
3: 66 percent / 50percent aq. AcOH / 24 h / 40 °C
4: 54 percent / H2 / Raney-Ni (W4) / ethanol
5: 99 percent / mCPBA / CHCl3 / 0.17 h / 25 °C
6: 58 percent / (n-Bu3Sn)2O, Br2 / CH2Cl2 / 24 h / 25 °C
7: 84 percent / H2 / Raney-Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
phenyl 2,6-anhydro-4-O-benzyl-3-C-methyl-3-O-methyl-1,2-dithio-β-L-altro-pyranoside
168072-11-5

phenyl 2,6-anhydro-4-O-benzyl-3-C-methyl-3-O-methyl-1,2-dithio-β-L-altro-pyranoside

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 90 percent / 4A molecular sieves, N-iodosuccinimide, TfOH / CH2Cl2 / 0.17 h / -35 °C
2: 66 percent / 50percent aq. AcOH / 12 h / 40 °C
3: 54 percent / H2 / Raney Ni (W4) / ethanol / 1.5 h / 40 °C
4: 99 percent / m-chloroperoxybenzoic acid / CH2Cl2 / 0.17 h / 25 °C
5: 58 percent / bis(tri-n-butyltin) oxide, Br2 / CH2Cl2 / 24 h / 25 °C
6: 84 percent / H2 / Rany Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
1-(2-pyrimidinethio) 3,4,6-trideoxy-2-O-methoxycarbonyl-3-(dimethylamino)-D-xylo-hexopyranoside
138603-63-1

1-(2-pyrimidinethio) 3,4,6-trideoxy-2-O-methoxycarbonyl-3-(dimethylamino)-D-xylo-hexopyranoside

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1: 63 percent / silver triflate, 4A molecular sieves / CH2Cl2; toluene / 4 h / 25 °C
2: 100 percent / m-chloroperoxybenzoic acid / CH2Cl2 / 0.25 h / 25 °C
3: 90 percent / 4A molecular sieves, N-iodosuccinimide, TfOH / CH2Cl2 / 0.17 h / -35 °C
4: 66 percent / 50percent aq. AcOH / 12 h / 40 °C
5: 54 percent / H2 / Raney Ni (W4) / ethanol / 1.5 h / 40 °C
6: 99 percent / m-chloroperoxybenzoic acid / CH2Cl2 / 0.17 h / 25 °C
7: 58 percent / bis(tri-n-butyltin) oxide, Br2 / CH2Cl2 / 24 h / 25 °C
8: 84 percent / H2 / Rany Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
(9S)-9-dihydroerythromycin A
63864-45-9

(9S)-9-dihydroerythromycin A

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 99 percent / m-chloroperoxybenzoic acid / CH2Cl2 / 0.17 h / 25 °C
2: 58 percent / bis(tri-n-butyltin) oxide, Br2 / CH2Cl2 / 24 h / 25 °C
3: 84 percent / H2 / Rany Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
Multi-step reaction with 3 steps
1: 99 percent / mCPBA / CHCl3 / 0.17 h / 25 °C
2: 58 percent / (n-Bu3Sn)2O, Br2 / CH2Cl2 / 24 h / 25 °C
3: 84 percent / H2 / Raney-Ni (W4) / ethanol / 1 h / 25 °C
View Scheme
D-desosamine
801972-88-3

D-desosamine

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
Multi-step reaction with 9 steps
1: (NCO2Et)2, P(n-Bu)3 / toluene / -30 - 25 °C
2: aq. NaHCO3 / CH2Cl2 / 25 °C
3: silver triflate / CH2Cl2; toluene / 25 °C
4: Pb(ClO4)2 / acetonitrile / 25 °C
5: MeOH
6: 75 percent / Na-Hg/MeOH
7: N-chlorosuccinimide / pyridine / 25 °C
8: AgF / hexamethylphosphoric acid triamide / 70 °C
9: H2O / 5 °C
View Scheme
Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: 72 percent / P(n-Bu)3 / CH2Cl2 / 0 °C
2: Pb(ClO4)2 / acetonitrile / 25 °C
3: MeOH
4: 75 percent / Na-Hg/MeOH
5: N-chlorosuccinimide / pyridine / 25 °C
6: AgF / hexamethylphosphoric acid triamide / 70 °C
7: H2O / 5 °C
View Scheme
erythromycylamine
26116-56-3

erythromycylamine

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: N-chlorosuccinimide / pyridine / 25 °C
2: AgF / hexamethylphosphoric acid triamide / 70 °C
3: H2O / 5 °C
View Scheme
4-O-acetyl-1-deoxy-1-(2-pyridylthio)-α-L-cladinoside
78443-20-6

4-O-acetyl-1-deoxy-1-(2-pyridylthio)-α-L-cladinoside

erythromycin
114-07-8

erythromycin

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: Pb(ClO4)2 / acetonitrile / 25 °C
2: MeOH
3: 75 percent / Na-Hg/MeOH
4: N-chlorosuccinimide / pyridine / 25 °C
5: AgF / hexamethylphosphoric acid triamide / 70 °C
6: H2O / 5 °C
View Scheme
succinic acid anhydride
108-30-5

succinic acid anhydride

erythromycin
114-07-8

erythromycin

2'-O-(3-carboxypropanoyl) erythromycin
20057-07-2

2'-O-(3-carboxypropanoyl) erythromycin

Conditions
ConditionsYield
In acetone at 50℃;100%
With acetone
With dichloromethane
erythromycin
114-07-8

erythromycin

erythromycin A 9-(E)-oxime
111321-02-9

erythromycin A 9-(E)-oxime

Conditions
ConditionsYield
With hydroxylamine; acetic acid In water; isopropyl alcohol at 50℃; for 15h; Inert atmosphere;100%
With hydroxylamine hydrochloride; sodium acetate; acetic acid In methanol at 55℃; for 24h;98%
With hydroxylamine hydrochloride; triethylamine In methanol for 96h; Heating / reflux;84%
Conditions
ConditionsYield
With water at 5 - 40℃; Product distribution / selectivity;99%
erythromycin
114-07-8

erythromycin

erythromycin A N-oxide
992-65-4

erythromycin A N-oxide

Conditions
ConditionsYield
With dihydrogen peroxide In methanol; water at 15 - 20℃; for 20h;98%
With dihydrogen peroxide In methanol; water at 20℃; for 19h;90%
With dihydrogen peroxide In methanol at 20℃;88%
With sodium periodate; ethanol; water
With dihydrogen peroxide
erythromycin
114-07-8

erythromycin

(9-E)-deoxo-9-hydroximinoerythromycin A
13127-18-9

(9-E)-deoxo-9-hydroximinoerythromycin A

Conditions
ConditionsYield
With hydroxylamine; acetic acid In isopropyl alcohol at 50℃; for 24h;95%
With hydroxylamine hydrochloride; triethylamine In methanol Reflux;93%
With hydroxylamine hydrochloride; potassium carbonate In methanol at 20℃; for 48h; Solvent; Reagent/catalyst; Temperature;88.2%
2-Methoxypropene
116-11-0

2-Methoxypropene

erythromycin
114-07-8

erythromycin

11,12-isopropylidene-8,9-anhydroerythromycin A 6,9-hemiacetal
110496-61-2

11,12-isopropylidene-8,9-anhydroerythromycin A 6,9-hemiacetal

Conditions
ConditionsYield
With pyridine hydrochloride In chloroform for 24h; Ambient temperature;94%
ethanol
64-17-5

ethanol

erythromycin
114-07-8

erythromycin

(2S,3S,4R,6S)-6-Ethoxy-4-methoxy-2,4-dimethyl-tetrahydro-pyran-3-ol
153029-63-1

(2S,3S,4R,6S)-6-Ethoxy-4-methoxy-2,4-dimethyl-tetrahydro-pyran-3-ol

Conditions
ConditionsYield
With toluene-4-sulfonic acid In acetonitrile for 1h; Ambient temperature;92%
acetic anhydride
108-24-7

acetic anhydride

erythromycin
114-07-8

erythromycin

2'-O-acetylerythromycin A
992-69-8, 86784-08-9

2'-O-acetylerythromycin A

Conditions
ConditionsYield
With pyridine In ethyl acetate at 20℃; for 1h;91%
In dichloromethane at 0 - 20℃; for 12h; Inert atmosphere;66%
In dichloromethane at 20℃;
With 1-methyl-1H-imidazole
In dichloromethane
erythromycin
114-07-8

erythromycin

(9S)-9-dihydroerythromycin A
63864-45-9

(9S)-9-dihydroerythromycin A

Conditions
ConditionsYield
Stage #1: erythromycin With sodium tetrahydroborate In diethyl ether; isopropyl alcohol at 0 - 20℃; for 3h;
Stage #2: With triethanolamine In diethyl ether; water; isopropyl alcohol for 2h; pH=6.5; Product distribution / selectivity;
86%
With sodium tetrahydroborate In diethyl ether; isopropyl alcohol at 0 - 20℃;86%
With aluminum oxide; sodium tetrahydroborate82%
sodium thiocyanide
540-72-7

sodium thiocyanide

erythromycin
114-07-8

erythromycin

erythromycin A thiocyanate
7704-67-8

erythromycin A thiocyanate

Conditions
ConditionsYield
Stage #1: erythromycin In acetone at 35℃; pH=8.5;
Stage #2: sodium thiocyanide In acetone Concentration; pH-value; Temperature; Solvent;
85.1%
Stage #1: erythromycin With LACTIC ACID; water at 5 - 40℃;
Stage #2: sodium thiocyanide In water at -15 - 10℃; Product distribution / selectivity;
Stage #1: erythromycin In acetone at 35℃; pH=8.5;
Stage #2: sodium thiocyanide In acetone
85.1 %Chromat.
erythromycin
114-07-8

erythromycin

N-Demethylerythromycin A
992-62-1

N-Demethylerythromycin A

Conditions
ConditionsYield
With sodium hydroxide; iodine; sodium acetate In methanol; water at 20 - 50℃; for 3.5h; pH=8 - 9;84%
With iodine; sodium acetate In methanol; water34%
With sodium hydroxide; iodine; sodium acetate In methanol; water for 2.5h;
acetic anhydride
108-24-7

acetic anhydride

erythromycin
114-07-8

erythromycin

2'O-acetylerythralosamine

2'O-acetylerythralosamine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 2h;84%
erythromycin
114-07-8

erythromycin

anhydroerythromycin A

anhydroerythromycin A

Conditions
ConditionsYield
With hydrogenchloride at 20℃; pH=1.7;81%
prop-2-yn-1-ol methanesulfonate
16156-58-4

prop-2-yn-1-ol methanesulfonate

tert-butyl 2-azidoacetate
6367-36-8

tert-butyl 2-azidoacetate

erythromycin
114-07-8

erythromycin

CH3O3S(1-)*C46H81N4O15(1+)
632329-94-3

CH3O3S(1-)*C46H81N4O15(1+)

Conditions
ConditionsYield
80%
benzyl chloroformate
501-53-1

benzyl chloroformate

erythromycin
114-07-8

erythromycin

A

O,N-dicarbobenzoxy-N-demethylerythromycin A enol ether

O,N-dicarbobenzoxy-N-demethylerythromycin A enol ether

B

2'-O,3'-N-bis(benzyloxycarbonyl)-N-demethylerythromycin A
81103-09-5

2'-O,3'-N-bis(benzyloxycarbonyl)-N-demethylerythromycin A

Conditions
ConditionsYield
With sodium hydrogencarbonate at 50℃; for 1h;A n/a
B 79%
C21H36O4
77379-13-6

C21H36O4

erythromycin
114-07-8

erythromycin

A

2'-O-linoleoylerythromycin A
112915-10-3, 112966-76-4

2'-O-linoleoylerythromycin A

B

4''-O-linoleoylerythromycin A
112915-11-4, 112966-77-5

4''-O-linoleoylerythromycin A

C

erythromycin, 2'-(ethyl carbonate)
7218-80-6

erythromycin, 2'-(ethyl carbonate)

Conditions
ConditionsYield
With pyridine In tetrahydrofuran at 20℃; for 10h;A 78%
B n/a
C 5%
benzyl chloroformate
501-53-1

benzyl chloroformate

erythromycin
114-07-8

erythromycin

2'-O,3'-N-bis(benzyloxycarbonyl)-N-demethylerythromycin A
81103-09-5

2'-O,3'-N-bis(benzyloxycarbonyl)-N-demethylerythromycin A

Conditions
ConditionsYield
With sodium hydrogencarbonate In toluene77%
With sodium hydrogencarbonate
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

erythromycin
114-07-8

erythromycin

2',4''-O-Bis(trimethylsilyl)erythromycin A
130073-47-1

2',4''-O-Bis(trimethylsilyl)erythromycin A

Conditions
ConditionsYield
With 1-(Trimethylsilyl)imidazole In ethyl acetate for 0.5h; Ambient temperature;76%
erythromycin
114-07-8

erythromycin

phenylcarbonochloridothioate
1005-56-7

phenylcarbonochloridothioate

erythromycin A-2'-phenylthionoformate
1379596-14-1

erythromycin A-2'-phenylthionoformate

Conditions
ConditionsYield
With 1,2,2,6,6-pentamethylpiperidine; 1-methyl-1H-imidazole In dichloromethane at 20℃; for 2h;76%
With triethylamine
methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

erythromycin
114-07-8

erythromycin

2',4''-di-O-methanesulfonylerythromycin A
71900-36-2

2',4''-di-O-methanesulfonylerythromycin A

Conditions
ConditionsYield
With triethylamine In acetone 1.) 0 to 3 deg C, 30 min, 2.) RT, 2 h;75.7%
erythromycin
114-07-8

erythromycin

α-(nucleozidediphosphate)-D-glucose

α-(nucleozidediphosphate)-D-glucose

2'-[O-(β-D-glucopyranosyl)]erythromycin A

2'-[O-(β-D-glucopyranosyl)]erythromycin A

Conditions
ConditionsYield
With glycosyltransferase OleD; Tris buffer at 37℃; pH=7.8;74%
octanoic acid anhydride
623-66-5

octanoic acid anhydride

erythromycin
114-07-8

erythromycin

A

C53H95NO15
914076-22-5

C53H95NO15

B

2',4"-dioctanoylerythromycin

2',4"-dioctanoylerythromycin

Conditions
ConditionsYield
With C47H62N8O10; triethylamine In chloroform Inert atmosphere;A 71%
B n/a
With pyridine Title compound not separated from byproducts.;
erythromycin
114-07-8

erythromycin

EM 201
857839-61-3

EM 201

Conditions
ConditionsYield
With acetic acid at 20℃; for 2h;71%
Product distribution / selectivity; Acidic aqueous solution;
acetic anhydride
108-24-7

acetic anhydride

erythromycin
114-07-8

erythromycin

A

C41H71NO15

C41H71NO15

B

2'-O-acetylerythromycin A
992-69-8, 86784-08-9

2'-O-acetylerythromycin A

Conditions
ConditionsYield
With pyridine at 25℃; for 72h;A 70%
B n/a
erythromycin
114-07-8

erythromycin

8,9-anhydroerythromycin A 6,9-hemiacetal
33396-29-1

8,9-anhydroerythromycin A 6,9-hemiacetal

Conditions
ConditionsYield
With acetic acid for 1h; Ambient temperature;68%
With acetic acid Erwaermen bei vermindertem Druck;
With acetic acid at 20℃;
With acetic acid at 20℃; for 0.75h;
erythromycin
114-07-8

erythromycin

3-tert-butoxycarbonylamino-propionic acid anhydride
120074-75-1

3-tert-butoxycarbonylamino-propionic acid anhydride

A

2'-3-(Boc)-propanoylerythromycin

2'-3-(Boc)-propanoylerythromycin

B

2',4"-di-3-(Boc)-propanoylerythromycin

2',4"-di-3-(Boc)-propanoylerythromycin

C

C53H93N3O19
1097637-89-2

C53H93N3O19

Conditions
ConditionsYield
With C47H62N8O10; triethylamine In chloroform at 20℃; for 65h; Inert atmosphere;A 13%
B 3%
C 68%
erythromycin
114-07-8

erythromycin

3-tert-butoxycarbonylamino-propionic acid anhydride
120074-75-1

3-tert-butoxycarbonylamino-propionic acid anhydride

A

2',4"-di-3-(Boc)-propanoylerythromycin

2',4"-di-3-(Boc)-propanoylerythromycin

B

C53H93N3O19
1097637-89-2

C53H93N3O19

Conditions
ConditionsYield
With C47H62N8O10; triethylamine In chloroform Inert atmosphere;A n/a
B 68%
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