Dayang Chem (Hangzhou) Co.,Ltd.
Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:6576-51-8
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryWuhan Han Sheng New Material Technology Co.，Ltd
Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Cas:6576-51-8
Min.Order:10 Kilogram
Negotiable
Type:Trading Company
inquiryShanghai Upbio Tech Co.,Ltd
1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ
Cas:6576-51-8
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryQingdao Beluga Import and Export Co., LTD
DISTAMYCIN A HYDROCHLORIDE CAS:6576-51-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic
Cas:6576-51-8
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryShandong Hanjiang Chemical Co., Ltd.
Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:6576-51-8
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co., Ltd.
Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:6576-51-8
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryBOC Sciences
BOC Sciences is committed to supplying cost-effective products and services. We provide Distamycin A hydrochloride (Cas No:6576-51-8). More information, please visit the website:https://www.bocsci.com/distamycinahydrochloride-cas-6576-51-8-item-1-1
Zibo Hangyu Biotechnology Development Co., Ltd
Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:6576-51-8
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryJiangsu Qianyu Molecular Technology Co., LTD.
Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an
Cas:6576-51-8
Min.Order:0
Negotiable
Type:Trading Company
inquiryEAST CHEMSOURCES LIMITED
factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Cas:6576-51-8
Min.Order:1 Kilogram
FOB Price: $18.0 / 20.0
Type:Trading Company
inquiryShandong Mopai Biotechnology Co., LTD
Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
Cas:6576-51-8
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryKAISA GROUP INC
1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:6576-51-8
Min.Order:1 Metric Ton
FOB Price: $1.5
Type:Trading Company
inquiryTriumph International Development Limilted
Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Business Custom Synthesis:
Cas:6576-51-8
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryGolden Pharma Co., Limited
GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation
Cas:6576-51-8
Min.Order:1 Kilogram
Negotiable
Type:Other
inquiryBluecrystal chem-union
We are a Union of chemistry in China, consists of chemists，engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp
Cas:6576-51-8
Min.Order:1 Metric Ton
FOB Price: $1.0
Type:Trading Company
inquiryHebei Mojin Biotechnology Co.,Ltd
1, High quality with competitive price:2, Fast and safe delivery3.Excellent pre-sales and after-sales service4. Well-trained and professional technologist and sales with rich experience in the field for 5-10 yearsAppearance:see detailed specification
Cas:6576-51-8
Min.Order:0
Negotiable
Type:Trading Company
inquiryHenan Tianfu Chemical Co., Ltd.
Our advantage:Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientif
Cas:6576-51-8
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHangzhou Dingyan Chem Co., Ltd
R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates
Cas:6576-51-8
Min.Order:0
Negotiable
Type:Manufacturers
inquiryHangzhou J&H Chemical Co., Ltd.
J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals
Cas:6576-51-8
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryXian Changyue Biological Technology Co., Ltd.
best seller Application:API
Cas:6576-51-8
Min.Order:0
Negotiable
Type:Manufacturers
inquiryWuhan Circle Star Chem-medical Technology co.,Ltd.
1,we produce and sell good chemicals around the world.2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%.3,our staff consists of highly qualified in
Cas:6576-51-8
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryHebei Sankai Chemical Technology Co., Ltd
1. Product advantages? High purity, all above 98.5%, no impurities after dissolution? We will test each batch to ensure quality? OEM and private brand services designed for free? Various cap colors available? We can also provide MT1 peptide powder2.
Cas:6576-51-8
Min.Order:0
Negotiable
Type:Trading Company
inquiryAntimex Chemical Limied
Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
Cas:6576-51-8
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryHangzhou Ocean Chemical Co., Ltd.
★.Best quality according to requirement ★.Competitive price in China market ★.Mature Technical support ★.Professional logistic support
Cas:6576-51-8
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryHubei Langyou International Trading Co., Ltd
TIANFU-CHEM DISTAMYCIN A HYDROCHLORIDE Application:TIANFU-CHEM DISTAMYCIN A HYDROCHLORIDE
DB BIOTECH CO., LTD
best seller Application:API
Cas:6576-51-8
Min.Order:0
Negotiable
Type:Trading Company
inquiryHangzhou Fandachem Co.,Ltd
1H-Pyrrole-2-carboxamide,N-[5-[[(3-amino-3-iminopropyl)amino]carbonyl]-1-methyl-1H-pyrrol-3-yl]-4-[[[4-(formylamino)-1-methyl-1H-pyrrol-2-yl]carbonyl]amino]-1-methyl-,hydrochloride (1:1) cas 6576-51-8Appearance:white crystalline powder Storage:Store
Wuhan ZeShanCheng Biomedical Technology Co., Ltd.
1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highl
Cas:6576-51-8
Min.Order:0
Negotiable
Type:Trading Company
inquiryHenan Kanbei Chemical Co.,LTD
factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Cas:6576-51-8
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryTaixing Hehao Chemical Materials Co.,Ltd
hight degree of purityAppearance:COA mentioned Storage:COA mentioned Package:Standard or custom package Application:hight degree of purity Transportation:Express/Sea/Air Port:Any port in China
Cas:6576-51-8
Min.Order:0
Negotiable
Type:Other
inquirySynthetic route
-
-
77727-43-6
N-Succinimidyl 4-<<<4-<<<4-(Formylamino)-1-methylpyrrol-2-yl>carbonyl>amino>-1-methylpyrrol-2-yl>carbonyl>amino>-1-methylpyrrole-2-carboxylate
-
-
77152-88-6
(1-amino-3-ammoniopropylidene)ammonium dihydrobromide
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| With hydrogenchloride; sodium hydrogencarbonate In 1,4-dioxane; water 1.) 15 min, ice-cooled, 2.) room temperature, overnight; Yield given; |
-
-
3786-88-7
1-methyl-4-<1-methyl-4-(1-methyl-4-aminopyrrole-2-carboxamido)pyrrole-2-carboxamido>pyrrole-2-carboxamidopropionamidine hydrochloride
-
-
3197-61-3
N-formylimidazole
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| In tetrahydrofuran; methanol at -40℃; for 0.5h; Yield given; |
| Conditions | Yield |
|---|---|
| Multi-step reaction with 8 steps 1: 43 percent / 1.) 70percent nitric acid, acetic anhydride / 1.) a) -15 deg C, 0.5 h, b) RT, 20 min 2: SOCl2 / tetrahydrofuran / 0.08 h / Heating 3: Hunig's base / tetrahydrofuran / -20 - 20 °C 4: 1.) H2, 2.) HCl / 10percent Pd/C / 1.) methanol, 40 deg C, 1 atm, 2.) isopropanol, -30 deg C 5: 64 percent / 1,8-bis(dimethylamino)naphthalene, dicyclohexylcarbodiimide / tetrahydrofuran; dimethylformamide / 3 h / Ambient temperature 6: 1.) HCl, 2.) NH3 / 1.) EtOH, RT, 1.5 h, 2.) EtOH, 1 h, RT 7: 70 percent / H2 / 10percent Pd/C / methanol / 40 °C 8: methanol; tetrahydrofuran / 0.5 h / -40 °C View Scheme | |
| Multi-step reaction with 8 steps 1: 43 percent / 1.) 70percent nitric acid, acetic anhydride / 1.) a) -15 deg C, 0.5 h, b) RT, 20 min 2: SOCl2 / tetrahydrofuran / 0.08 h / Heating 3: 1.) H2, 2.) Hunig's base / 10percent Pd/C / 1.) MeOH, 1 atm, 2.) THF, 3) THF, RT, 30 min 4: 95 percent / NaOH / H2O; ethanol / Heating 5: 64 percent / 1,8-bis(dimethylamino)naphthalene, dicyclohexylcarbodiimide / tetrahydrofuran; dimethylformamide / 3 h / Ambient temperature 6: 1.) HCl, 2.) NH3 / 1.) EtOH, RT, 1.5 h, 2.) EtOH, 1 h, RT 7: 70 percent / H2 / 10percent Pd/C / methanol / 40 °C 8: methanol; tetrahydrofuran / 0.5 h / -40 °C View Scheme |
-
-
13138-78-8
1-methyl-4-nitro-pyrrol-2-carboxylic acid
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 7 steps 1: SOCl2 / tetrahydrofuran / 0.08 h / Heating 2: Hunig's base / tetrahydrofuran / -20 - 20 °C 3: 1.) H2, 2.) HCl / 10percent Pd/C / 1.) methanol, 40 deg C, 1 atm, 2.) isopropanol, -30 deg C 4: 64 percent / 1,8-bis(dimethylamino)naphthalene, dicyclohexylcarbodiimide / tetrahydrofuran; dimethylformamide / 3 h / Ambient temperature 5: 1.) HCl, 2.) NH3 / 1.) EtOH, RT, 1.5 h, 2.) EtOH, 1 h, RT 6: 70 percent / H2 / 10percent Pd/C / methanol / 40 °C 7: methanol; tetrahydrofuran / 0.5 h / -40 °C View Scheme | |
| Multi-step reaction with 7 steps 1: SOCl2 / tetrahydrofuran / 0.08 h / Heating 2: 1.) H2, 2.) Hunig's base / 10percent Pd/C / 1.) MeOH, 1 atm, 2.) THF, 3) THF, RT, 30 min 3: 95 percent / NaOH / H2O; ethanol / Heating 4: 64 percent / 1,8-bis(dimethylamino)naphthalene, dicyclohexylcarbodiimide / tetrahydrofuran; dimethylformamide / 3 h / Ambient temperature 5: 1.) HCl, 2.) NH3 / 1.) EtOH, RT, 1.5 h, 2.) EtOH, 1 h, RT 6: 70 percent / H2 / 10percent Pd/C / methanol / 40 °C 7: methanol; tetrahydrofuran / 0.5 h / -40 °C View Scheme | |
| Multi-step reaction with 8 steps 1: H2, 1.0 M Na2CO3(aq.) / 5percent Pd/C / 3.5 h / 3102.9 Torr / Ambient temperature 2: tetrahydrofuran; diethyl ether / 1.) 1 h, ice cooled, 2.) 2 h, ambient temperature 3: 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide hydrochloride / dimethylformamide / 40 °C 4: TFA / CH2Cl2 5: EDC / dimethylformamide / 40 °C 6: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 7: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 8: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme |
-
-
97950-76-0
1-methyl-4-(1-methyl-4-nitropyrrole-2-carboxamido)pyrrole-2-carboxylic acid
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 4 steps 1: 64 percent / 1,8-bis(dimethylamino)naphthalene, dicyclohexylcarbodiimide / tetrahydrofuran; dimethylformamide / 3 h / Ambient temperature 2: 1.) HCl, 2.) NH3 / 1.) EtOH, RT, 1.5 h, 2.) EtOH, 1 h, RT 3: 70 percent / H2 / 10percent Pd/C / methanol / 40 °C 4: methanol; tetrahydrofuran / 0.5 h / -40 °C View Scheme |
-
-
69910-20-9
methyl 1-methyl-4-(1-methyl-4-nitropyrrole-2-carboxamido)pyrrole-2-carbonate
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 5 steps 1: 95 percent / NaOH / H2O; ethanol / Heating 2: 64 percent / 1,8-bis(dimethylamino)naphthalene, dicyclohexylcarbodiimide / tetrahydrofuran; dimethylformamide / 3 h / Ambient temperature 3: 1.) HCl, 2.) NH3 / 1.) EtOH, RT, 1.5 h, 2.) EtOH, 1 h, RT 4: 70 percent / H2 / 10percent Pd/C / methanol / 40 °C 5: methanol; tetrahydrofuran / 0.5 h / -40 °C View Scheme |
-
-
28494-51-1
1-methyl-4-nitro-1H-pyrrole-2-carbonyl chloride
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 6 steps 1: Hunig's base / tetrahydrofuran / -20 - 20 °C 2: 1.) H2, 2.) HCl / 10percent Pd/C / 1.) methanol, 40 deg C, 1 atm, 2.) isopropanol, -30 deg C 3: 64 percent / 1,8-bis(dimethylamino)naphthalene, dicyclohexylcarbodiimide / tetrahydrofuran; dimethylformamide / 3 h / Ambient temperature 4: 1.) HCl, 2.) NH3 / 1.) EtOH, RT, 1.5 h, 2.) EtOH, 1 h, RT 5: 70 percent / H2 / 10percent Pd/C / methanol / 40 °C 6: methanol; tetrahydrofuran / 0.5 h / -40 °C View Scheme | |
| Multi-step reaction with 6 steps 1: 1.) H2, 2.) Hunig's base / 10percent Pd/C / 1.) MeOH, 1 atm, 2.) THF, 3) THF, RT, 30 min 2: 95 percent / NaOH / H2O; ethanol / Heating 3: 64 percent / 1,8-bis(dimethylamino)naphthalene, dicyclohexylcarbodiimide / tetrahydrofuran; dimethylformamide / 3 h / Ambient temperature 4: 1.) HCl, 2.) NH3 / 1.) EtOH, RT, 1.5 h, 2.) EtOH, 1 h, RT 5: 70 percent / H2 / 10percent Pd/C / methanol / 40 °C 6: methanol; tetrahydrofuran / 0.5 h / -40 °C View Scheme |
-
-
13138-76-6
1-methyl-4-nitropyrrole-2-carboxylic acid methyl ester
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 8 steps 1: 92 percent / aq. NaOH / Heating 2: SOCl2 / tetrahydrofuran / 0.08 h / Heating 3: Hunig's base / tetrahydrofuran / -20 - 20 °C 4: 1.) H2, 2.) HCl / 10percent Pd/C / 1.) methanol, 40 deg C, 1 atm, 2.) isopropanol, -30 deg C 5: 64 percent / 1,8-bis(dimethylamino)naphthalene, dicyclohexylcarbodiimide / tetrahydrofuran; dimethylformamide / 3 h / Ambient temperature 6: 1.) HCl, 2.) NH3 / 1.) EtOH, RT, 1.5 h, 2.) EtOH, 1 h, RT 7: 70 percent / H2 / 10percent Pd/C / methanol / 40 °C 8: methanol; tetrahydrofuran / 0.5 h / -40 °C View Scheme | |
| Multi-step reaction with 8 steps 1: 92 percent / aq. NaOH / Heating 2: SOCl2 / tetrahydrofuran / 0.08 h / Heating 3: 1.) H2, 2.) Hunig's base / 10percent Pd/C / 1.) MeOH, 1 atm, 2.) THF, 3) THF, RT, 30 min 4: 95 percent / NaOH / H2O; ethanol / Heating 5: 64 percent / 1,8-bis(dimethylamino)naphthalene, dicyclohexylcarbodiimide / tetrahydrofuran; dimethylformamide / 3 h / Ambient temperature 6: 1.) HCl, 2.) NH3 / 1.) EtOH, RT, 1.5 h, 2.) EtOH, 1 h, RT 7: 70 percent / H2 / 10percent Pd/C / methanol / 40 °C 8: methanol; tetrahydrofuran / 0.5 h / -40 °C View Scheme |
-
-
3185-95-3
1-methyl-4-nitro-1H-pyrrole-2-carboxylic acid (2-cyanoethyl)amide
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 5 steps 1: 1.) H2, 2.) HCl / 10percent Pd/C / 1.) methanol, 40 deg C, 1 atm, 2.) isopropanol, -30 deg C 2: 64 percent / 1,8-bis(dimethylamino)naphthalene, dicyclohexylcarbodiimide / tetrahydrofuran; dimethylformamide / 3 h / Ambient temperature 3: 1.) HCl, 2.) NH3 / 1.) EtOH, RT, 1.5 h, 2.) EtOH, 1 h, RT 4: 70 percent / H2 / 10percent Pd/C / methanol / 40 °C 5: methanol; tetrahydrofuran / 0.5 h / -40 °C View Scheme |
-
-
2522-28-3
3-<1-methyl-4-<1-methyl-4-(1-methyl-4-nitropyrrole-2-carboxamido)pyrrole-2-carboxamido>pyrrole-2-carboxamido>propionitrile
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: 1.) HCl, 2.) NH3 / 1.) EtOH, RT, 1.5 h, 2.) EtOH, 1 h, RT 2: 70 percent / H2 / 10percent Pd/C / methanol / 40 °C 3: methanol; tetrahydrofuran / 0.5 h / -40 °C View Scheme |
-
-
6576-50-7
N-(3-amino-3-iminopropyl)-1-methyl-4-{[(1-methyl-4-{[(1-methyl-4-nitro-1H-pyrrol-2-yl)carbonyl]amino}-1H-pyrrol-2-yl)carbonyl]amino}-1H-pyrrole-2-carboxamide hydrochloride
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: 70 percent / H2 / 10percent Pd/C / methanol / 40 °C 2: methanol; tetrahydrofuran / 0.5 h / -40 °C View Scheme |
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 4 steps 1: 64 percent / 1,8-bis(dimethylamino)naphthalene, dicyclohexylcarbodiimide / tetrahydrofuran; dimethylformamide / 3 h / Ambient temperature 2: 1.) HCl, 2.) NH3 / 1.) EtOH, RT, 1.5 h, 2.) EtOH, 1 h, RT 3: 70 percent / H2 / 10percent Pd/C / methanol / 40 °C 4: methanol; tetrahydrofuran / 0.5 h / -40 °C View Scheme |
-
-
45776-13-4
4-amino-1-methylpyrrole-2-carboxylic acid
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 7 steps 1: tetrahydrofuran; diethyl ether / 1.) 1 h, ice cooled, 2.) 2 h, ambient temperature 2: 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide hydrochloride / dimethylformamide / 40 °C 3: TFA / CH2Cl2 4: EDC / dimethylformamide / 40 °C 5: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 6: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 7: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme | |
| Multi-step reaction with 10 steps 1: tetrahydrofuran; diethyl ether / 1.) 1 h, ice cooled, 2.) 2 h, ambient temperature 2: Cs2CO3 / ethanol; H2O 3: dimethylformamide / 40 °C 4: TFA / CH2Cl2 / 1 h / Ambient temperature; stoppered flask 5: 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide hydrochloride / dimethylformamide / 40 °C 6: TFA / CH2Cl2 7: EDC / dimethylformamide / 40 °C 8: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 9: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 10: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme | |
| Multi-step reaction with 10 steps 1: tetrahydrofuran; diethyl ether / 1.) 1 h, ice cooled, 2.) 2 h, ambient temperature 2: Cs2CO3 / ethanol; H2O 3: dimethylformamide / 40 °C 4: TFA / CH2Cl2 / 1 h / Ambient temperature; stoppered flask 5: tetramethylguanidine / dimethylsulfoxide / 20 h / 50 °C 6: TFA / CH2Cl2 7: EDC / dimethylformamide / 40 °C 8: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 9: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 10: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme | |
| Multi-step reaction with 8 steps 1: tetrahydrofuran; diethyl ether / 1.) 1 h, ice cooled, 2.) 2 h, ambient temperature 2: 71 percent / N,N'-dicyclohexylcarbodiimide / dimethylformamide / 20 h / Ambient temperature 3: tetramethylguanidine / dimethylsulfoxide / 20 h / 50 °C 4: TFA / CH2Cl2 5: EDC / dimethylformamide / 40 °C 6: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 7: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 8: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme | |
| Multi-step reaction with 5 steps 1: 2.5 h / ice-bath 2: EDC / dimethylformamide / 40 °C 3: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 4: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 5: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme |
| Conditions | Yield |
|---|---|
| Multi-step reaction with 9 steps 1: 69 percent / 2 M NaOH / ethanol / 1.5 h / Heating 2: H2, 1.0 M Na2CO3(aq.) / 5percent Pd/C / 3.5 h / 3102.9 Torr / Ambient temperature 3: tetrahydrofuran; diethyl ether / 1.) 1 h, ice cooled, 2.) 2 h, ambient temperature 4: 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide hydrochloride / dimethylformamide / 40 °C 5: TFA / CH2Cl2 6: EDC / dimethylformamide / 40 °C 7: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 8: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 9: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme | |
| Multi-step reaction with 12 steps 1: 69 percent / 2 M NaOH / ethanol / 1.5 h / Heating 2: H2, 1.0 M Na2CO3(aq.) / 5percent Pd/C / 3.5 h / 3102.9 Torr / Ambient temperature 3: tetrahydrofuran; diethyl ether / 1.) 1 h, ice cooled, 2.) 2 h, ambient temperature 4: Cs2CO3 / ethanol; H2O 5: dimethylformamide / 40 °C 6: TFA / CH2Cl2 / 1 h / Ambient temperature; stoppered flask 7: 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide hydrochloride / dimethylformamide / 40 °C 8: TFA / CH2Cl2 9: EDC / dimethylformamide / 40 °C 10: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 11: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 12: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme | |
| Multi-step reaction with 12 steps 1: 69 percent / 2 M NaOH / ethanol / 1.5 h / Heating 2: H2, 1.0 M Na2CO3(aq.) / 5percent Pd/C / 3.5 h / 3102.9 Torr / Ambient temperature 3: tetrahydrofuran; diethyl ether / 1.) 1 h, ice cooled, 2.) 2 h, ambient temperature 4: Cs2CO3 / ethanol; H2O 5: dimethylformamide / 40 °C 6: TFA / CH2Cl2 / 1 h / Ambient temperature; stoppered flask 7: tetramethylguanidine / dimethylsulfoxide / 20 h / 50 °C 8: TFA / CH2Cl2 9: EDC / dimethylformamide / 40 °C 10: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 11: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 12: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme | |
| Multi-step reaction with 10 steps 1: 69 percent / 2 M NaOH / ethanol / 1.5 h / Heating 2: H2, 1.0 M Na2CO3(aq.) / 5percent Pd/C / 3.5 h / 3102.9 Torr / Ambient temperature 3: tetrahydrofuran; diethyl ether / 1.) 1 h, ice cooled, 2.) 2 h, ambient temperature 4: 71 percent / N,N'-dicyclohexylcarbodiimide / dimethylformamide / 20 h / Ambient temperature 5: tetramethylguanidine / dimethylsulfoxide / 20 h / 50 °C 6: TFA / CH2Cl2 7: EDC / dimethylformamide / 40 °C 8: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 9: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 10: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme | |
| Multi-step reaction with 7 steps 1: 69 percent / 2 M NaOH / ethanol / 1.5 h / Heating 2: H2, 1.0 M Na2CO3(aq.) / 5percent Pd/C / 3.5 h / 3102.9 Torr / Ambient temperature 3: 2.5 h / ice-bath 4: EDC / dimethylformamide / 40 °C 5: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 6: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 7: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme |
-
-
77716-14-4
Benzyl 4-Amino-1-methylpyrrole-2-carboxylate
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 6 steps 1: 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide hydrochloride / dimethylformamide / 40 °C 2: TFA / CH2Cl2 3: EDC / dimethylformamide / 40 °C 4: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 5: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 6: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme | |
| Multi-step reaction with 6 steps 1: tetramethylguanidine / dimethylsulfoxide / 20 h / 50 °C 2: TFA / CH2Cl2 3: EDC / dimethylformamide / 40 °C 4: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 5: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 6: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme |
-
-
77716-19-9
Benzyl 4-<<(4-Amino-1-methylpyrrol-2-yl)carbonyl>amino>-1-methylpyrrole-2-carboxylate
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 4 steps 1: EDC / dimethylformamide / 40 °C 2: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 3: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 4: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme |
-
-
77716-18-8
4-formamido-1-methylimidazole-2-carboxylic acid
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 4 steps 1: EDC / dimethylformamide / 40 °C 2: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 3: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 4: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme |
-
-
77716-11-1
4-[(tert-butoxycarbonyl)amino]-1-methyl-1H-pyrrole-2-carboxylic acid
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 6 steps 1: 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide hydrochloride / dimethylformamide / 40 °C 2: TFA / CH2Cl2 3: EDC / dimethylformamide / 40 °C 4: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 5: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 6: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme | |
| Multi-step reaction with 9 steps 1: Cs2CO3 / ethanol; H2O 2: dimethylformamide / 40 °C 3: TFA / CH2Cl2 / 1 h / Ambient temperature; stoppered flask 4: 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide hydrochloride / dimethylformamide / 40 °C 5: TFA / CH2Cl2 6: EDC / dimethylformamide / 40 °C 7: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 8: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 9: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme | |
| Multi-step reaction with 9 steps 1: Cs2CO3 / ethanol; H2O 2: dimethylformamide / 40 °C 3: TFA / CH2Cl2 / 1 h / Ambient temperature; stoppered flask 4: tetramethylguanidine / dimethylsulfoxide / 20 h / 50 °C 5: TFA / CH2Cl2 6: EDC / dimethylformamide / 40 °C 7: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 8: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 9: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme | |
| Multi-step reaction with 7 steps 1: 71 percent / N,N'-dicyclohexylcarbodiimide / dimethylformamide / 20 h / Ambient temperature 2: tetramethylguanidine / dimethylsulfoxide / 20 h / 50 °C 3: TFA / CH2Cl2 4: EDC / dimethylformamide / 40 °C 5: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 6: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 7: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme |
-
-
77716-13-3
benzyl 4-<<(tert-butyloxy)carbonyl>amino>-1-methyl-pyrrole-2-carboxylate
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 7 steps 1: TFA / CH2Cl2 / 1 h / Ambient temperature; stoppered flask 2: 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide hydrochloride / dimethylformamide / 40 °C 3: TFA / CH2Cl2 4: EDC / dimethylformamide / 40 °C 5: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 6: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 7: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme | |
| Multi-step reaction with 7 steps 1: TFA / CH2Cl2 / 1 h / Ambient temperature; stoppered flask 2: tetramethylguanidine / dimethylsulfoxide / 20 h / 50 °C 3: TFA / CH2Cl2 4: EDC / dimethylformamide / 40 °C 5: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 6: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 7: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme |
-
-
77716-16-6
4-tert-butoxycarbonylamino-1-methyl-1H-pyrrole-2-carboxylic acid benzotriazol-1yl ester
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 6 steps 1: tetramethylguanidine / dimethylsulfoxide / 20 h / 50 °C 2: TFA / CH2Cl2 3: EDC / dimethylformamide / 40 °C 4: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 5: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 6: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme |
-
-
77716-15-5
benzyl 4-<<<4-<<(tert-butyloxy)carbonyl>amino>-1-methyl-pyrrol-2-yl>carbonyl>amino>-1-methyl-pyrrole-2-carboxylate
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 5 steps 1: TFA / CH2Cl2 2: EDC / dimethylformamide / 40 °C 3: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 4: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 5: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme |
-
-
77716-21-3
4-(4-(4-formamido-1-methyl-1H-pyrrole-2-carboxamido)-1-methyl-1H-pyrrole-2-carboxamido)-1-methyl-1H-pyrrole-2-carboxylic acid
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 2: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme |
-
-
77716-20-2
Benzyl 4-<<<4-<<<4-(Formylamino)-1-methylpyrrol-2-yl>carbonyl>amino>-1-methylpyrrol-2-yl>carbonyl>amino>-1-methylpyrrole-2-carboxylate
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 2: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 3: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme |
-
-
77716-12-2
Caesium; 4-tert-butoxycarbonylamino-1-methyl-1H-pyrrole-2-carboxylate
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 8 steps 1: dimethylformamide / 40 °C 2: TFA / CH2Cl2 / 1 h / Ambient temperature; stoppered flask 3: 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide hydrochloride / dimethylformamide / 40 °C 4: TFA / CH2Cl2 5: EDC / dimethylformamide / 40 °C 6: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 7: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 8: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme | |
| Multi-step reaction with 8 steps 1: dimethylformamide / 40 °C 2: TFA / CH2Cl2 / 1 h / Ambient temperature; stoppered flask 3: tetramethylguanidine / dimethylsulfoxide / 20 h / 50 °C 4: TFA / CH2Cl2 5: EDC / dimethylformamide / 40 °C 6: H2 / 5percent Pd/C / dimethylformamide / 2 h / 3102.9 Torr / Ambient temperature 7: 88 percent / DCC / dimethylformamide / 1.) 70 min, 0 deg C, 2.) 40 deg C, overnight 8: 1.) NaHCO3, 2.) HCl / H2O; dioxane / 1.) 15 min, ice-cooled, 2.) room temperature, overnight View Scheme |
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| With sodium hydroxide In methanol for 24h; Heating; | 100% |
| Conditions | Yield |
|---|---|
| In methanol at 20℃; for 24h; | 95% |
-
-
420-04-2
CYANAMID
-
-
6576-51-8
distamycin A hydrochloride
-
-
194483-83-5
N-[5-({[5-({[3-amino-3-(cyanoimino)propyl]amino}carbonyl)-1-methyl-1H-pyrrol-3-yl]amino}carbonyl)-1-methyl-1H-pyrrol-3-yl]-4-(formylamino)-1-methyl-1H-pyrrole-2-carboxamide
| Conditions | Yield |
|---|---|
| Stage #1: CYANAMID With sodium hydride In N,N-dimethyl-formamide at 20℃; for 0.5h; Stage #2: distamycin A hydrochloride In N,N-dimethyl-formamide for 2h; | 93% |
| Stage #1: CYANAMID With sodium hydride In N,N-dimethyl-formamide for 0.5h; Stage #2: distamycin A hydrochloride In N,N-dimethyl-formamide for 5h; | 92% |
| Stage #1: CYANAMID With sodium hydride In DMF (N,N-dimethyl-formamide) at 20℃; for 0.5h; Stage #2: distamycin A hydrochloride In DMF (N,N-dimethyl-formamide) at 20℃; for 2h; Stage #3: With acetic acid In DMF (N,N-dimethyl-formamide) pH=7; |
| Conditions | Yield |
|---|---|
| With sodium hydride In N,N-dimethyl-formamide at 20℃; for 5.5h; | 92% |
-
-
6576-51-8
distamycin A hydrochloride
-
-
71084-59-8
N-(5-{[(5-{[(2-cyanoethyl)amino]carbonyl}-1-methyl-1H-pyrrol-3-yl)amino]carbonyl}-1-methyl-1H-pyrrol-3-yl)-4-(formylamino)-1-methyl-1H-pyrrole-2-carboxamide
| Conditions | Yield |
|---|---|
| With sodium carbonate In N,N-dimethyl-formamide at 70℃; for 3h; | 87% |
| With succinic acid anhydride; sodium carbonate In N,N-dimethyl-formamide at 70℃; for 3h; | 87% |
| With succinic acid anhydride; potassium carbonate In N,N-dimethyl-formamide for 3h; Ambient temperature; | 75% |
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| With sodium hydroxide In methanol at 60℃; for 4h; | 75% |
| Conditions | Yield |
|---|---|
| In water; N,N-dimethyl-formamide at 20℃; for 29h; | 73% |
| Conditions | Yield |
|---|---|
| In water; N,N-dimethyl-formamide at 20℃; for 12h; | 73% |
| In DMF (N,N-dimethyl-formamide) for 8h; |
-
-
6576-51-8
distamycin A hydrochloride
-
-
74-89-5
methylamine
-
A
-
863319-29-3
N-[5-({[5-({[3-amino-3-(N-methylcarbamoyl)ethyl]amino}carbonyl)-1-methyl-1H-pyrrol-3-yl]amino}carbonyl)-1-methyl-1H-pyrrol-3-yl]-4-(formylamino)-1-methyl-1H-pyrrole-2-carboxamide
-
B
-
17165-05-8
N-[5-({[5-({[2-(carbamoyl)ethyl]amino}carbonyl)-1-methyl-1H-pyrrol-3-yl]amino}carbonyl)-1-methyl-1H-pyrrol-3-yl]-4-(formylamino)-1-methyl-1H-pyrrole-2-carboxamide
| Conditions | Yield |
|---|---|
| With water In N,N-dimethyl-formamide at 80℃; for 3h; | A 18% B 57% |
-
-
6576-51-8
distamycin A hydrochloride
-
-
203258-75-7
N-[5-({[5-({[3-amino-3-(hydroxyimino)propyl]amino}carbonyl)-1-methyl-1H-pyrrol-3-yl]amino}carbonyl)-1-methyl-1H-pyrrol-3-yl]-4-(formylamino)-1-methyl-1H-pyrrole-2-carboxamide
| Conditions | Yield |
|---|---|
| With hydroxylamine In N,N-dimethyl-formamide at 70℃; for 2h; | 52% |
| With TEA; hydroxylamine hydrochloride In N,N-dimethyl-formamide at 70℃; for 1h; | 52% |
| Conditions | Yield |
|---|---|
| In N,N-dimethyl-formamide at 80℃; for 6h; | 42% |
| Conditions | Yield |
|---|---|
| In water; N,N-dimethyl-formamide at 80℃; for 3h; | 32% |
| Conditions | Yield |
|---|---|
| In N,N-dimethyl-formamide at 20℃; for 72h; | 20% |
| Conditions | Yield |
|---|---|
| With potassium carbonate In N,N-dimethyl-formamide Ambient temperature; |
| Conditions | Yield |
|---|---|
| With potassium carbonate In N,N-dimethyl-formamide Ambient temperature; |
| Conditions | Yield |
|---|---|
| With base In N,N-dimethyl-formamide at 70℃; Substitution; |
-
-
6576-51-8
distamycin A hydrochloride
-
-
17165-05-8
N-[5-({[5-({[2-(carbamoyl)ethyl]amino}carbonyl)-1-methyl-1H-pyrrol-3-yl]amino}carbonyl)-1-methyl-1H-pyrrol-3-yl]-4-(formylamino)-1-methyl-1H-pyrrole-2-carboxamide
| Conditions | Yield |
|---|---|
| With sodium hydroxide In acetonitrile at 70℃; Hydrolysis; |
-
-
6576-51-8
distamycin A hydrochloride
-
-
203258-75-7
C22H27N9O5
| Conditions | Yield |
|---|---|
| With hydroxylamine In N,N-dimethyl-formamide at 70℃; Substitution; |
| Conditions | Yield |
|---|---|
| With base In N,N-dimethyl-formamide at 70℃; Substitution; |
| Conditions | Yield |
|---|---|
| With base In N,N-dimethyl-formamide at 70℃; Substitution; |
| Conditions | Yield |
|---|---|
| With base In N,N-dimethyl-formamide at 70℃; Substitution; |
| Conditions | Yield |
|---|---|
| With base In N,N-dimethyl-formamide at 70℃; Substitution; |
-
-
6576-51-8
distamycin A hydrochloride
-
-
17165-10-5
4-amino-N-(5-{[(5-{[(3-amino-3-iminopropyl)amino]carbonyl}-1-methyl-1H-pyrrol-3-yl)amino]carbonyl}-1-methyl-1H-pyrrol-3-yl)-1-methyl-1H-pyrrole-2-carboxamide dihydrochloride
| Conditions | Yield |
|---|---|
| With hydrogenchloride In methanol at 20℃; for 24h; |
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: 57 percent / H2O / dimethylformamide / 3 h / 80 °C 2: aq. HCl / aq. ethanol / 24 h / 20 °C 3: TEA / dimethylformamide / 3 h / 20 °C View Scheme |
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: 18 percent / H2O / dimethylformamide / 3 h / 80 °C 2: aq. HCl / aq. ethanol / 24 h / 20 °C 3: TEA / dimethylformamide / 3 h / 20 °C View Scheme |
-
-
6576-51-8
distamycin A hydrochloride
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: 52 percent / NH2OH*HCl; TEA / dimethylformamide / 1 h / 70 °C 2: aq. HCl / aq. ethanol / 24 h / 20 °C 3: TEA / dimethylformamide / 3 h / 20 °C View Scheme |
Related products
Raw Materials
Hot Products
XiAbout|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View