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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

4-Hydroxy-6-methyl-2-pyrone Manufacturer/High quality/Best price/In stock

Cas:675-10-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 4-Hydroxy-6-Methyl-2-Pyrone supplier in China

Cas:675-10-5

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

4-Hydroxy-6-methyl-2-pyrone CAS 675-10-5 triacetate lactone CAS no 675-10-5 3,5-Dihydroxysorbic acid delta-lactone 4-Hydroxy-6-methyl-2-pyrone triacetate lactone 3,5-Dihydroxysorbic acid delta-lactone 4-Hydroxy-6-methyl-2-pyroneCAS 675-10-5

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

4-Hydroxy-6-methyl-2-pyrone

Cas:675-10-5

Min.Order:1 Gram

FOB Price: $1.0 / 99.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

TIANFU CHEM--4-Hydroxy-6-methyl-2-pyrone_

Cas:675-10-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 675-10-5 with best quality

Cas:675-10-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

4-Hydroxy-6-methyl-2-pyrone 675-10-5

Cas:675-10-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Leader Biochemical Group

About Product Details Items Specifications Test Results Appearance White to white crystalline powde

China factory Supply High Quality 4-Hydroxy-6-methyl-2-pyrone CAS 675-10-5

Cas:675-10-5

Min.Order:1 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Pharmaceutical Intermediate, 4-Hydroxy-6-methyl-2-pyrone CAS:675-10-5

Cas:675-10-5

Min.Order:1 Kilogram

FOB Price: $62.9 / 68.2

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

4-Hydroxy-6-methyl-2-pyrone CAS:675-10-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organi

4-Hydroxy-6-methyl-2-pyrone CAS:675-10-5

Cas:675-10-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

4-Hydroxy-6-methyl-2-pyrone

Cas:675-10-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:675-10-5

Cas:675-10-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

HOT SELLER triacetate lactone CAS675-10-5

Cas:675-10-5

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

4-Hydroxy-6-methyl-2-pyrone

Cas:675-10-5

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

4-Hydroxy-6-methyl-2-pyrone

Cas:675-10-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 4-Hydroxy-6-methyl-2-pyrone

Cas:675-10-5

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

4-Hydroxy-6-methyl-2-pyrone

Cas:675-10-5

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 6-methy1-4-hydroxy-2-pyrones

Cas:675-10-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

Hot Sale High Purity 4-Hydroxy-6-methyl-2-pyrone with factory priceAppearance:white powder Storage:Store in dry, dark and ventilated place Package:according to customers' requirements Application:Pharmaceutical Intermediates / Active Pharmaceutical I

Hot Sale High Purity 4-Hydroxy-6-methyl-2-pyrone with factory price

Cas:675-10-5

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

4-Hydroxy-6-methyl-2-pyrone

Cas:675-10-5

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white crystals Storage:Sealed and stored Package:25kg/drum Application:Synthetic chemical hybridizing agents and antibiotics cefpiramide Transportation:as per your request Port:Shang

4-Hydroxy-6-methyl-2-pyrone

Cas:675-10-5

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Siwei Development Group Ltd.

Product name: 4-Hydroxy-6-Methyl-2-Pyrone CAS No.:675-10-5 Molecule Formula:C6H6O3 Molecule Weight:126.11 Purity: 98.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard

High Quality 4-Hydroxy-6-Methyl-2-Pyrone

Cas:675-10-5

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

4-Hydroxy-6-methyl-2-pyrone

Cas:675-10-5

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

4-Hydroxy-6-methyl-2-pyrone Chemical Properties Melting point 188-190 °C (dec.) (lit.) Boiling point 174.21°C (rough estimate) density 1.2048 (rough estimate) refractive index 1.4189 (estimate) storage temp. Keep in dark p

4-Hydroxy-6-methyl-2-pyrone

Cas:675-10-5

Min.Order:1 Gram

FOB Price: $66.0

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

4-Hydroxy-6-methyl-2-pyrone

Cas:675-10-5

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

4-Hydroxy-6-methyl-2-pyrone

Cas:675-10-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

4-Hydroxy-6-methyl-2-pyrone

Cas:675-10-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

4-Hydroxy-6-methyl-2-pyrone

Cas:675-10-5

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service an

4-Hydroxy-6-methyl-2-pyrone

Cas:675-10-5

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

6-Methyl-4-hydroxy-2-pyrone

Cas:675-10-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one
771-03-9

3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

Conditions
ConditionsYield
With sulfuric acid In water at 130℃; for 0.216667h; Flow reactor;96%
With sulfuric acid at 130℃; for 0.25h;90%
With sulfuric acid at 130℃; for 0.25h; Cooling with ice;89%
3,5-dioxohexanoic acid
2140-49-0

3,5-dioxohexanoic acid

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

Conditions
ConditionsYield
With trifluoroacetic acid; trifluoroacetic anhydride for 0.5h; Heating;94%
With 1,1'-carbonyldiimidazole In diethyl ether at 0℃; for 2h; Yield given;
2,2-dimethyl-6-(2-oxo-2-methylethyl)-4H-1,3-dioxin-4-one
130473-38-0

2,2-dimethyl-6-(2-oxo-2-methylethyl)-4H-1,3-dioxin-4-one

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

Conditions
ConditionsYield
In toluene at 100℃; for 0.5h;92%
In toluene for 0.166667h; Heating;66%
In toluene Reflux;
2,2-dimethyl-5-(1-hydroxy-3-oxobutylidene)-1,3-dioxane-4,6-dione
84257-12-5

2,2-dimethyl-5-(1-hydroxy-3-oxobutylidene)-1,3-dioxane-4,6-dione

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

Conditions
ConditionsYield
In 1,4-dioxane for 2h; Heating;89%
3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one
771-03-9

3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one

A

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

B

2,6-dimethyl-4-oxopyran-3-carboxylic acid
3265-58-5

2,6-dimethyl-4-oxopyran-3-carboxylic acid

Conditions
ConditionsYield
With sulfuric acid In water at 130℃; for 0.25h; Temperature; Flow reactor;A 81%
B 6 %Spectr.
4-Hydroxy-6-trimethylsilanylmethyl-pyran-2-one

4-Hydroxy-6-trimethylsilanylmethyl-pyran-2-one

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran for 0.5h; Ambient temperature;80%
2,2-dimethyl-5-(3-oxobutanoyl)-1,3-dioxane-4,6-dione
143456-22-8

2,2-dimethyl-5-(3-oxobutanoyl)-1,3-dioxane-4,6-dione

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

Conditions
ConditionsYield
In toluene Heating;76%
1-styrenyloxytrimethylsilane
13735-81-4

1-styrenyloxytrimethylsilane

malonoyl dichloride
1663-67-8

malonoyl dichloride

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

Conditions
ConditionsYield
67%
isopropenyl isopropyl ether
4188-63-0

isopropenyl isopropyl ether

malonoyl dichloride
1663-67-8

malonoyl dichloride

A

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

B

Phloroglucinmonoisopropylether
64507-45-5

Phloroglucinmonoisopropylether

Conditions
ConditionsYield
In diethyl etherA 24%
B 65%
With potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride 1) Et2O, -19 deg C, 2 h, 2) Et2O, r.t., 4 h; Yield given. Multistep reaction. Yields of byproduct given;
Dehydracetic acid
520-45-6

Dehydracetic acid

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

Conditions
ConditionsYield
In sulfuric acid; water at 120℃; for 1.5h; Deacetylation;60%
acetic anhydride
108-24-7

acetic anhydride

2-(1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)ethylidene)-N-phenylhydrazinecarbothioamide

2-(1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)ethylidene)-N-phenylhydrazinecarbothioamide

A

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

B

N-(5-methyl-[1,3,4]thiadiazol-2-yl)-N-phenyl-acetamide
7118-95-8

N-(5-methyl-[1,3,4]thiadiazol-2-yl)-N-phenyl-acetamide

Conditions
ConditionsYield
With zinc(II) chloride at 23 - 25℃; for 72h;A 30%
B 57%
acetic anhydride
108-24-7

acetic anhydride

3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one thiosemicarbazone
75843-20-8

3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one thiosemicarbazone

A

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

B

N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide
13053-83-3

N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide

Conditions
ConditionsYield
for 0.166667h; Heating;A 50%
B 55%
propionic acid anhydride
123-62-6

propionic acid anhydride

2-(1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)ethylidene)-N-phenylhydrazinecarbothioamide

2-(1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)ethylidene)-N-phenylhydrazinecarbothioamide

A

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

B

N-(5-Methyl-[1,3,4]thiadiazol-2-yl)-N-phenyl-propionamide

N-(5-Methyl-[1,3,4]thiadiazol-2-yl)-N-phenyl-propionamide

Conditions
ConditionsYield
With zinc(II) chloride at 23 - 25℃; for 45h;A n/a
B 54%
propionic acid anhydride
123-62-6

propionic acid anhydride

3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one thiosemicarbazone
75843-20-8

3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one thiosemicarbazone

A

N-(5-methyl-1,3,4-thiadiazol-2-yl)-propionamide
25958-41-2

N-(5-methyl-1,3,4-thiadiazol-2-yl)-propionamide

B

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

Conditions
ConditionsYield
at 120 - 130℃; for 0.25h;A 53%
B 45%
2-Methoxypropene
116-11-0

2-Methoxypropene

malonoyl dichloride
1663-67-8

malonoyl dichloride

A

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

B

5-methoxyresorcinol
2174-64-3

5-methoxyresorcinol

Conditions
ConditionsYield
In diethyl etherA 43%
B 52%
With potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride 1) Et2O, -19 deg C, 2 h, 2) Et2O, r.t., 4 h; Yield given. Multistep reaction. Yields of byproduct given;
2-(1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)ethylidene)-N-phenylhydrazinecarbothioamide

2-(1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)ethylidene)-N-phenylhydrazinecarbothioamide

A

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

B

3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one
771-03-9

3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one

C

5-methyl-N-phenyl-1,3,4-thiadiazol-2-amine
7159-68-4

5-methyl-N-phenyl-1,3,4-thiadiazol-2-amine

Conditions
ConditionsYield
In ethanol; acetic acid for 2.41667h; Heating;A 20%
B n/a
C 44%
2-ethoxyprop-1-ene
926-66-9

2-ethoxyprop-1-ene

malonoyl dichloride
1663-67-8

malonoyl dichloride

A

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

B

Phloroglucinmonoethylether
28334-98-7

Phloroglucinmonoethylether

Conditions
ConditionsYield
In diethyl etherA 42%
B 43%
With potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride 1) Et2O, -19 deg C, 2 h, 2) Et2O, r.t., 4 h; Yield given. Multistep reaction. Yields of byproduct given;
3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one
771-03-9

3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one

A

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

B

3,5-dioxohexanoic acid methyl ester
29736-80-9

3,5-dioxohexanoic acid methyl ester

C

acetoacetic acid methyl ester
105-45-3

acetoacetic acid methyl ester

Conditions
ConditionsYield
With sodium methylate In methanol; benzene for 18h; Heating;A 7%
B 18%
C 16%
phenyldiazomethane
908094-04-2

phenyldiazomethane

4-methoxy-6-(phenylthiomethyl)-2H-pyran-2-one
93338-99-9

4-methoxy-6-(phenylthiomethyl)-2H-pyran-2-one

A

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

B

meso-5,5'-(1,2-diphenyl-1,2-ethanediyl)bis(4-methoxy-6-methyl-2H-pyran-2-one)

meso-5,5'-(1,2-diphenyl-1,2-ethanediyl)bis(4-methoxy-6-methyl-2H-pyran-2-one)

(+/-)-5,5'-(1,2-diphenyl-1,2-ethanediyl)bis(4-methoxy-6-methyl-2H-pyran-2-one)

(+/-)-5,5'-(1,2-diphenyl-1,2-ethanediyl)bis(4-methoxy-6-methyl-2H-pyran-2-one)

Conditions
ConditionsYield
Multistep reaction. Yields of byproduct given;
3,5-dioxohexanoic acid methyl ester
29736-80-9

3,5-dioxohexanoic acid methyl ester

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

Conditions
ConditionsYield
With sulfuric acid at 80℃;
α-acetyl-allene-α.γ-dicarboxylic acid ester

α-acetyl-allene-α.γ-dicarboxylic acid ester

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

Conditions
ConditionsYield
With hydrogenchloride
With potassium hydroxide
acetylcoenzyme A
72-89-9

acetylcoenzyme A

S-(hydrogen malonyl)coenzyme A
524-14-1

S-(hydrogen malonyl)coenzyme A

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

Conditions
ConditionsYield
With 6-hydroxymellein synthase from carrot root cells; sodium chloride; Coenzyme A; NADPH In water at 37℃; pH=6.0; Enzyme kinetics; Further Variations:; Reagents; pH-values;
With 2-pyrone synthase
S-acetyl coenzyme A
72-89-9

S-acetyl coenzyme A

malonyl coenzyme A

malonyl coenzyme A

A

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

B

4-hydroxy-6-(2-oxopropyl)pyran-2-one
10310-07-3

4-hydroxy-6-(2-oxopropyl)pyran-2-one

Conditions
ConditionsYield
With type III polyketide synthase RppA from S. griseus; 2-hydroxyethanethiol In various solvent(s) at 37℃; for 2h; pH=7.5;A 1 % Turnov.
B 5 % Turnov.
2,7-dimethyl-4H-pyrano<3,2-c>-2H-pyran-4,5-dione
33176-11-3

2,7-dimethyl-4H-pyrano<3,2-c>-2H-pyran-4,5-dione

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 52 percent / MeONa / benzene / 18 h / Heating
2: conc. H2SO4 / 80 °C
View Scheme
acetylacetone
123-54-6

acetylacetone

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.) butyl-lithium, di-isopropylamine / 1.) THF, hexane, -78 deg C, 30 min; 2.) THF, hexane, up to RT
2: 94 percent / trifluoroacetic acid, trifluoroacetic anhydride / 0.5 h / Heating
View Scheme
acetylacetone enol
26567-75-9

acetylacetone enol

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: N,N'-carbonyldiimidazole (CDI) / diethyl ether / 2 h / 0 °C
View Scheme
acetylcoenzyme A
72-89-9

acetylcoenzyme A

S-(hydrogen malonyl)coenzyme A
524-14-1

S-(hydrogen malonyl)coenzyme A

A

6-(2,4-dihydroxy-6-methylphenyl)-4-hydroxy-2H-pyran-2-one

6-(2,4-dihydroxy-6-methylphenyl)-4-hydroxy-2H-pyran-2-one

B

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

C

4-hydroxy-6-(2-oxopropyl)pyran-2-one
10310-07-3

4-hydroxy-6-(2-oxopropyl)pyran-2-one

D

4-hydroxy-6-(2',4'-dioxo-pentyl)-pyrone
83095-25-4

4-hydroxy-6-(2',4'-dioxo-pentyl)-pyrone

Conditions
ConditionsYield
Stage #1: acetylcoenzyme A; S-(hydrogen malonyl)coenzyme A With recombinant N-His-tagged hexaketide synthase of Drosophyllum lusitanicum Link at 30℃; for 1h; pH=7.0; aq. buffer; Enzymatic reaction;
Stage #2: Acidic aq. solution;
S-(hydrogen malonyl)coenzyme A
524-14-1

S-(hydrogen malonyl)coenzyme A

A

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

B

(E)-4-hydroxy-6-(prop-1-en-1-yl)-2H-pyran-2-one
21534-03-2

(E)-4-hydroxy-6-(prop-1-en-1-yl)-2H-pyran-2-one

C

C10H10O3
1187429-74-8

C10H10O3

D

1,3E,5E,7E,9E,11E,13E-pentadecaheptaene
676579-01-4

1,3E,5E,7E,9E,11E,13E-pentadecaheptaene

E

C12H12O3
1187429-75-9

C12H12O3

F

(3E,5E,7E,9E,11E,13E)-pentadeca-3,5,7,9,11,13-hexaen-2-one
1187429-73-7

(3E,5E,7E,9E,11E,13E)-pentadeca-3,5,7,9,11,13-hexaen-2-one

G

3-oxohexadeca-4,6,8,10,12,14-hexaenoic acid
1187429-71-5

3-oxohexadeca-4,6,8,10,12,14-hexaenoic acid

Conditions
ConditionsYield
With calicheamicin polyketide synthase CalE8; calicheamicin thioesterase CalE7; NADPH In glycerol at 24℃; for 2h; pH=7; aq. phosphate buffer; Enzymatic reaction;
6-(2-hydroxypropyl)-2,2-dimethyl-4H-1,3-dioxin-4-one
136801-79-1

6-(2-hydroxypropyl)-2,2-dimethyl-4H-1,3-dioxin-4-one

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Dess-Martin periodane / 20 °C
2: toluene / Reflux
View Scheme
Multi-step reaction with 2 steps
1: Dess-Martin periodane / dichloromethane / 1.5 h / 20 °C
2: toluene / 0.5 h / 100 °C
View Scheme
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

acetic acid
64-19-7

acetic acid

3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one
771-03-9

3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In toluene Reflux;100%
With dmap; dicyclohexyl-carbodiimide In toluene at 100℃; for 2h;86.4%
With dmap; dicyclohexyl-carbodiimide In toluene at 20 - 100℃;
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

4-hydroxy-6-methyl-tetrahydro-2H-pyran-2-one
27751-97-9

4-hydroxy-6-methyl-tetrahydro-2H-pyran-2-one

Conditions
ConditionsYield
palladium 10% on activated carbon In butan-1-ol at 49.84℃; under 15514.9 Torr; for 8h; Product distribution / selectivity;99.4%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

3,3’-(4-methoxyphenyl)methylenebis(4-hydroxy-6-methyl-2H-pyran-2-one)
82420-03-9

3,3’-(4-methoxyphenyl)methylenebis(4-hydroxy-6-methyl-2H-pyran-2-one)

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene at 20℃; for 9h;99%
With nano Fe3O4 supported carbamoylsulfamic acid functionalized on organosilicate In neat (no solvent) at 100℃; for 1h; Reagent/catalyst; Green chemistry;96%
With piperidine; acetic acid In ethanol at 60℃; for 2.5h;95%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

acetaldehyde
75-07-0

acetaldehyde

1,1-bis(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)ethane
92405-61-3

1,1-bis(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)ethane

Conditions
ConditionsYield
With piperidine; acetic acid In ethanol for 24h; Ambient temperature;99%
In chloroform at 40℃; for 16h;60%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

1-cyclohexene-1-carboxaldehyde
1192-88-7

1-cyclohexene-1-carboxaldehyde

3-Methyl-1H,7H-5a,6,8,9-tetrahydro-1-oxopyrano[4,3-b][1]benzopyran
194796-93-5

3-Methyl-1H,7H-5a,6,8,9-tetrahydro-1-oxopyrano[4,3-b][1]benzopyran

Conditions
ConditionsYield
With 2,4,8,10-Tetra-tert-butyl-6-hydroxydibenzo[d,f][1,3,2]dioxaphosphepine 6-oxide; sodium sulfate In toluene at 60℃; Inert atmosphere;99%
With 2,4,8,10-Tetra-tert-butyl-6-hydroxydibenzo[d,f][1,3,2]dioxaphosphepine 6-oxide; sodium sulfate In toluene at 60℃; Inert atmosphere; regioselective reaction;99%
With L-proline In ethyl acetate at 70℃; for 24h;76%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

acetone
67-64-1

acetone

4-methoxy-6-methyl-2H-pyran-2-one
672-89-9

4-methoxy-6-methyl-2H-pyran-2-one

Conditions
ConditionsYield
With potassium carbonate In various solvent(s) for 8h; Methylation; Heating;99%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

trans-Crotonaldehyde
123-73-9

trans-Crotonaldehyde

2,7-dimethyl-2H,5H-pyrano<3,2-c>pyran-5-one
92405-72-6

2,7-dimethyl-2H,5H-pyrano<3,2-c>pyran-5-one

Conditions
ConditionsYield
With 2,4,8,10-Tetra-tert-butyl-6-hydroxydibenzo[d,f][1,3,2]dioxaphosphepine 6-oxide; sodium sulfate In toluene at 60℃; Inert atmosphere; regioselective reaction;99%
With piperidine; acetic anhydride In ethyl acetate at -10 - 85℃;66%
Stage #1: trans-Crotonaldehyde With piperidine; acetic anhydride In ethyl acetate at -10 - 85℃;
Stage #2: 4-hydroxy-6-methyl-2-pyron In ethyl acetate at 85℃; Further stages.;
66%
With piperdinium acetate; sodium sulfate In ethyl acetate at 80 - 90℃; for 18h;
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

3,3-dimethyl acrylaldehyde
107-86-8

3,3-dimethyl acrylaldehyde

2,2,7-trimethyl-2H-pyrano[4,3-b]pyran-5-one
220633-52-3

2,2,7-trimethyl-2H-pyrano[4,3-b]pyran-5-one

Conditions
ConditionsYield
With 2,4,8,10-Tetra-tert-butyl-6-hydroxydibenzo[d,f][1,3,2]dioxaphosphepine 6-oxide; sodium sulfate In toluene at 60℃; Inert atmosphere;99%
With 2,4,8,10-Tetra-tert-butyl-6-hydroxydibenzo[d,f][1,3,2]dioxaphosphepine 6-oxide; sodium sulfate In toluene at 60℃; Inert atmosphere; regioselective reaction;99%
In neat (no solvent) at 20 - 120℃; for 10h; Microwave irradiation; Green chemistry;94%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

3-methylbenzene-1,2-diol
488-17-5

3-methylbenzene-1,2-diol

7,8-dihydroxy-3,6-dimethyl-1H-pyrano[4,3-b]benzofuran-1-one

7,8-dihydroxy-3,6-dimethyl-1H-pyrano[4,3-b]benzofuran-1-one

Conditions
ConditionsYield
With Trametes versicolor laccase; oxygen In acetate buffer at 20℃; for 3.5h; pH=4.37;99%
With laccase from Trametes versicolor at 20℃; for 3h; pH=4.4; aq. acetate buffer; Enzymatic reaction; regioselective reaction;99%
With sodium acetate; potassium hexacyanoferrate(III) In water80%
With sodium acetate In water Electrochemical reaction;67%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

crotonaldehyde
123-73-9

crotonaldehyde

2,7-dimethyl-2H,5H-pyrano<3,2-c>pyran-5-one
92405-72-6

2,7-dimethyl-2H,5H-pyrano<3,2-c>pyran-5-one

Conditions
ConditionsYield
With 2,4,8,10-Tetra-tert-butyl-6-hydroxydibenzo[d,f][1,3,2]dioxaphosphepine 6-oxide; sodium sulfate In toluene at 60℃; Inert atmosphere;99%
With 4 A molecular sieve In dichloromethane53%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

benzenesulfenyl chloride
931-59-9

benzenesulfenyl chloride

4-hydroxy-6-methyl-3-(phenylsulfanyl)-2H-pyran-2-one
53603-21-7

4-hydroxy-6-methyl-3-(phenylsulfanyl)-2H-pyran-2-one

Conditions
ConditionsYield
With hydrogenchloride In benzene99%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

2-methyl-2-pentenal
1115-11-3

2-methyl-2-pentenal

2,3,7-trimethyl-2H-pyrano[4,3-b]pyran-5-one

2,3,7-trimethyl-2H-pyrano[4,3-b]pyran-5-one

Conditions
ConditionsYield
With 2,4,8,10-Tetra-tert-butyl-6-hydroxydibenzo[d,f][1,3,2]dioxaphosphepine 6-oxide; sodium sulfate In toluene at 60℃; Inert atmosphere;99%
With 2,4,8,10-Tetra-tert-butyl-6-hydroxydibenzo[d,f][1,3,2]dioxaphosphepine 6-oxide; sodium sulfate In toluene at 60℃; Inert atmosphere; regioselective reaction;99%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

(E/Z)-3,7-dimethyl-2,6-octadienal
5392-40-5

(E/Z)-3,7-dimethyl-2,6-octadienal

2,7-dimethyl-2-(4-methyl-pent-3-enyl)-2H-pyrano[4,3-b]pyran-5-one

2,7-dimethyl-2-(4-methyl-pent-3-enyl)-2H-pyrano[4,3-b]pyran-5-one

Conditions
ConditionsYield
With 2,4,8,10-Tetra-tert-butyl-6-hydroxydibenzo[d,f][1,3,2]dioxaphosphepine 6-oxide; sodium sulfate In toluene at 60℃; Inert atmosphere;99%
With 2,4,8,10-Tetra-tert-butyl-6-hydroxydibenzo[d,f][1,3,2]dioxaphosphepine 6-oxide; sodium sulfate In toluene at 60℃; Inert atmosphere; regioselective reaction;99%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

3,5-Dibromosalicylaldehyde
90-59-5

3,5-Dibromosalicylaldehyde

6,8-dibromo-3-acetoacetylcoumarin
98253-83-9

6,8-dibromo-3-acetoacetylcoumarin

Conditions
ConditionsYield
With 1-n-butyl-3-methylimidazolim bromide at 90℃; for 4h;99%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

C14H18O3
1198426-98-0

C14H18O3

Conditions
ConditionsYield
With 2,4,8,10-Tetra-tert-butyl-6-hydroxydibenzo[d,f][1,3,2]dioxaphosphepine 6-oxide; sodium sulfate In toluene at 60℃; Inert atmosphere; regioselective reaction;99%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

methyl benzylidenepyruvate
107969-78-8

methyl benzylidenepyruvate

(R)-methyl 2-hydroxy-7-methyl-5-oxo-4-phenyl-2,3,4,5-tetrahydropyrano[4,3-b]pyran-2-carboxylate

(R)-methyl 2-hydroxy-7-methyl-5-oxo-4-phenyl-2,3,4,5-tetrahydropyrano[4,3-b]pyran-2-carboxylate

Conditions
ConditionsYield
With C29H29F6N3OS In diethyl ether at 20℃; for 1h; Michael addition; optical yield given as %ee; enantioselective reaction;99%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

methyl (E)-2-oxo-4-(4-chlorophenyl)but-3-enoate
42393-11-3

methyl (E)-2-oxo-4-(4-chlorophenyl)but-3-enoate

(R)-methyl 4-(4-chlorophenyl)-2-hydroxy-7-methyl-5-oxo-2,3,4,5-tetrahydropyrano[4,3-b]pyran-2-carboxylate

(R)-methyl 4-(4-chlorophenyl)-2-hydroxy-7-methyl-5-oxo-2,3,4,5-tetrahydropyrano[4,3-b]pyran-2-carboxylate

Conditions
ConditionsYield
With C29H29F6N3OS In diethyl ether at 20℃; for 1h; Michael addition; optical yield given as %ee; enantioselective reaction;99%
2-aminopyridine
504-29-0

2-aminopyridine

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

pyrimidine-2,4,5,6(1H,3H)-tetraone
61066-33-9, 61066-34-0, 61066-35-1, 61127-23-9

pyrimidine-2,4,5,6(1H,3H)-tetraone

2-aminopyridinium 3-(5-hydroxy-2,4,6-trioxohexahydropyrimidin-5-yl)-6-methyl-2,4-dioxo-3,4-dihydro-2H-pyran-3-ide
1367747-80-5

2-aminopyridinium 3-(5-hydroxy-2,4,6-trioxohexahydropyrimidin-5-yl)-6-methyl-2,4-dioxo-3,4-dihydro-2H-pyran-3-ide

Conditions
ConditionsYield
In chloroform for 5h; Reflux;99%
2-aminopyridine
504-29-0

2-aminopyridine

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

1,3-dimethylalloxan
2757-85-9

1,3-dimethylalloxan

2-aminopyridinium 3-(5-hydroxy-1,3-dimethyl-2,4,6-trioxohexahydropyrimidin-5-yl)-6-methyl-2,4-dioxo-3,4-dihydro-2H-pyran-3-ide
1367748-29-5

2-aminopyridinium 3-(5-hydroxy-1,3-dimethyl-2,4,6-trioxohexahydropyrimidin-5-yl)-6-methyl-2,4-dioxo-3,4-dihydro-2H-pyran-3-ide

Conditions
ConditionsYield
In chloroform for 18h; Reflux;99%
(5-methyl-pyridin-2-yl)amine
1603-41-4

(5-methyl-pyridin-2-yl)amine

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

pyrimidine-2,4,5,6(1H,3H)-tetraone
61066-33-9, 61066-34-0, 61066-35-1, 61127-23-9

pyrimidine-2,4,5,6(1H,3H)-tetraone

2-amino-5-methylpyridinium 3-(5-hydroxy-2,4,6-trioxohexahydropyrimidin-5-yl)-6-methyl-2,4-dioxo-3,4-dihydro-2H-pyran-3-ide
1367748-08-0

2-amino-5-methylpyridinium 3-(5-hydroxy-2,4,6-trioxohexahydropyrimidin-5-yl)-6-methyl-2,4-dioxo-3,4-dihydro-2H-pyran-3-ide

Conditions
ConditionsYield
In chloroform for 5h; Reflux;99%
3-methylpyridin-2-ylamine
1603-40-3

3-methylpyridin-2-ylamine

4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

pyrimidine-2,4,5,6(1H,3H)-tetraone
61066-33-9, 61066-34-0, 61066-35-1, 61127-23-9

pyrimidine-2,4,5,6(1H,3H)-tetraone

2-amino-3-methylpyridinium 3-(5-hydroxy-2,4,6-trioxohexahydropyrimidin-5-yl)-6-methyl-2,4-dioxo-3,4-dihydro-2H-pyran-3-ide
1367748-01-3

2-amino-3-methylpyridinium 3-(5-hydroxy-2,4,6-trioxohexahydropyrimidin-5-yl)-6-methyl-2,4-dioxo-3,4-dihydro-2H-pyran-3-ide

Conditions
ConditionsYield
In chloroform for 3h; Reflux;99%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

(R/S)-1,2-Butandiol-1-<(4-methylbenzol)sulfonat>
143693-24-7

(R/S)-1,2-Butandiol-1-<(4-methylbenzol)sulfonat>

4-[1-(4-toluenesulfonyloxy)but-2-yloxy]-6-methyl-2-pyrone
1642145-05-8

4-[1-(4-toluenesulfonyloxy)but-2-yloxy]-6-methyl-2-pyrone

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In dichloromethane at 0 - 25℃; Mitsunobu Displacement; Inert atmosphere;99%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

tributylphosphine
998-40-3

tributylphosphine

5-bromosalicyclaldehyde
1761-61-1

5-bromosalicyclaldehyde

3-((5-bromo-2-hydroxyphenyl)(tributylphosphonio)methyl)-6-methyl-2-oxo-2H-pyran-4-olate

3-((5-bromo-2-hydroxyphenyl)(tributylphosphonio)methyl)-6-methyl-2-oxo-2H-pyran-4-olate

Conditions
ConditionsYield
With pyrrolidine; benzoic acid In tetrahydrofuran at 30℃; for 5h; Schlenk technique; Inert atmosphere;99%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

N-(4-(1-hydroxy-1,3-diphenylprop-2-yn-1-yl)phenyl)pivalamide

N-(4-(1-hydroxy-1,3-diphenylprop-2-yn-1-yl)phenyl)pivalamide

N-(4-(7-methyl-5-oxo-2,4-diphenyl-2H,5H-pyrano[4,3-b]pyran-2-yl)phenyl)pivalamide

N-(4-(7-methyl-5-oxo-2,4-diphenyl-2H,5H-pyrano[4,3-b]pyran-2-yl)phenyl)pivalamide

Conditions
ConditionsYield
With diphenyl hydrogen phosphate In dichloromethane at 20℃; for 2h;99%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

di-isopropyl azodicarboxylate
2446-83-5

di-isopropyl azodicarboxylate

1-tert-butyldimethylsilyloxy-2-hydroxybutane
136984-23-1

1-tert-butyldimethylsilyloxy-2-hydroxybutane

4-{1-[(tert-butyldimethylsilanyloxy)methyl]propoxy}-6-methyl-2-pyrone
1259313-03-5

4-{1-[(tert-butyldimethylsilanyloxy)methyl]propoxy}-6-methyl-2-pyrone

Conditions
ConditionsYield
Stage #1: 4-hydroxy-6-methyl-2-pyron; 1-tert-butyldimethylsilyloxy-2-hydroxybutane With triphenylphosphine In tetrahydrofuran at 0℃; Inert atmosphere;
Stage #2: di-isopropyl azodicarboxylate In tetrahydrofuran at 20℃; for 16h; Inert atmosphere;
98.4%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

1-tert-butyldimethylsilyloxy-2-hydroxybutane
136984-23-1

1-tert-butyldimethylsilyloxy-2-hydroxybutane

4-{1-[(tert-butyldimethylsilanyloxy)methyl]propoxy}-6-methyl-2-pyrone
1259313-03-5

4-{1-[(tert-butyldimethylsilanyloxy)methyl]propoxy}-6-methyl-2-pyrone

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In dichloromethane at 0 - 25℃; Mitsunobu Displacement; Inert atmosphere;98.4%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

3-nitro-benzaldehyde
99-61-6

3-nitro-benzaldehyde

3,3'-((3-nitrophenyl)methylene)bis(4-hydroxy-6-methyl-2H-pyran-2-one)
132559-96-7

3,3'-((3-nitrophenyl)methylene)bis(4-hydroxy-6-methyl-2H-pyran-2-one)

Conditions
ConditionsYield
With nano Fe3O4 supported 2-carbamoylhydrazine-1-sulfonic acid functionalized on organosilicate In neat (no solvent) at 100℃; for 0.666667h; Reagent/catalyst; Green chemistry;98%
With sodium dodecyl-sulfate In water at 90℃; for 6h;93%
With Fe3O4(at)SiO2/(CH2)3-[imidazolium-SO3H]Cl at 90℃; for 0.416667h; Green chemistry;91%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

benzaldehyde
100-52-7

benzaldehyde

4,4'-dihydroxy-6,6'-dimethyl-3,3'-(phenylmethylene)bis(pyran)-2,2'-dione
16929-83-2

4,4'-dihydroxy-6,6'-dimethyl-3,3'-(phenylmethylene)bis(pyran)-2,2'-dione

Conditions
ConditionsYield
With piperidine; acetic acid In ethanol for 2h;98%
With nano Fe3O4 supported carbamoylsulfamic acid functionalized on organosilicate In neat (no solvent) at 100℃; for 0.266667h; Catalytic behavior; Reagent/catalyst; Temperature; Time; Green chemistry;95%
With Fe3O4(at)SiO2/(CH2)3-[imidazolium-SO3H]Cl at 90℃; for 0.25h; Green chemistry;94%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

salicylaldehyde
90-02-8

salicylaldehyde

(1-(2-oxo-2H-chromen-3-yl)butane-1,3-dione)
13252-79-4

(1-(2-oxo-2H-chromen-3-yl)butane-1,3-dione)

Conditions
ConditionsYield
With 1-n-butyl-3-methylimidazolim bromide at 90℃; for 4h;98%
With β‐cyclodextrin In water at 70℃; for 0.5h; Green chemistry;97%
molecular sieve In ethanol for 0.166667h; Heating;89%
4-hydroxy-6-methyl-2-pyron
675-10-5

4-hydroxy-6-methyl-2-pyron

benzylamine
100-46-9

benzylamine

(Z)-N-benzyl-5-(benzylamino)-3-oxohex-4-enamide
84259-92-7

(Z)-N-benzyl-5-(benzylamino)-3-oxohex-4-enamide

Conditions
ConditionsYield
In ethanol for 4h; Reflux;98%
In methanol for 1h; Heating; 1/1 proportion;

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