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Chengdu Baishixing Science and Technology Industry Co., Ltd.

The area of Chengdu Baishixing is 35,000 square metre , the staff members are 88, our output value is over 120 millions per year. Baishiying cooporates with Life Science Academy of Wuhan University to develop amino acids series products.We ha

D-Lysine hydrochloride

Cas:7274-88-6

Min.Order:25 Kilogram

Negotiable

Type:Manufacturers

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

D-Lysine hydrochloride Manufacturer/High quality/Best price/In stock

Cas:7274-88-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality D-Lysine Hydrochloride supplier in China

Cas:7274-88-6

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White crystalline powder Storage:Cool dry place Package:1kg/foill bag;25kg/drum Appli

Factory supply D-Lysine hydrochloride Cas 7274-88-6 with high quality and best price

Cas:7274-88-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Hangzhou Think Chemical Co. Ltd

D-Lysine HCl[CAS:7274-88-6] Name D-Lysine hydrochloride Synonyms D-LYS hydrochloride; D-2,6-Diaminohexanoic acid hydrochloride Molecular Formula

Good quality D-Lysine HCl

Cas:7274-88-6

Min.Order:1 Kilogram

Negotiable

Type:Other

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply D-Lysine Hydrochloride

Cas:7274-88-6

Min.Order:1

Negotiable

Type:Other

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SICHUAN TONGSHENG AMINOACID CO.LTD

Sichuan Tongsheng is the most strongest manufacturer and exporter of amino acids and their derivatives in China, we have the best quality and price. Guarantee high quality, competive price and reliable service. We fully compliance with ISO9001:2008,

D-Lysine hydrochloride

Cas:7274-88-6

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

D-Lysine monohydrochloride

Cas:7274-88-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Product Name: D-Lysine hydrochloride Synonyms: D-LYSINE HCL;D-LYSINE HYDROCHLORIDE;D-LYSINE HYDROCHLORIDE SALT;D-(-)-LYSINE MONOHYDROCHLORIDE;D-LYSINE MONOHYDROCHLORIDE;D-LYS HYDROCHLORIDE;D-2,6-DIAMINOCAPROIC ACID, HYDROCHLORIDE;D-2,6-DIAMINOHEXA

7274-88-6 D-Lysine hydrochloride

Cas:7274-88-6

Min.Order:1 Kilogram

FOB Price: $500.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufactu

CAS. 7274-88-6 D-Lysine Hydrochloride

Cas:7274-88-6

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 7274-88-6 with best quality

Cas:7274-88-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product Name: D-Lysine hydrochloride Synonyms: CAS: 7274-88-6 MF: C6H15ClN2O2 MW: 182.65 EINECS: 230-691-6

D-Lysine hydrochloride 7274-88-6

Cas:7274-88-6

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

D-Lysine monohydrochloride cas7274-88-6

Cas:7274-88-6

Min.Order:1 Kilogram

FOB Price: $6.0 / 10.0

Type:Trading Company

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO

D-lysine hydrochloride manufacturer/supplier

Cas:7274-88-6

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:white crystal powder Storage:ln stock Package:25kg/drum Application:D-Lysine is used as a component of a wide array of polymers (poly-D-lysine), surfactants and biofilms to confer a positive (cationic) charge. Transportation:Express/Sea/A

D-lysine D-Lysine hydrochloride white crystals factory supply

Cas:7274-88-6

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

D-Lysine hydrochloride 7274-88-6

Cas:7274-88-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Pharmaceutical Intermediate, D-Lysine hydrochloride CAS: 7274-88-6

Cas:7274-88-6

Min.Order:1 Kilogram

FOB Price: $84.0 / 87.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, steroids, pharmaceutical

D-Lysine hydrochloride/7274-88-6/D-Lysine hydrochloride Manufacturer

Cas:7274-88-6

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:7274-88-6

Cas:7274-88-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

D-Lysine hydrochloride

Cas:7274-88-6

Min.Order:1 Kilogram

FOB Price: $20.0 / 60.0

Type:Lab/Research institutions

inquiry

Leader Biochemical Group

PRODUCT DETAILS

China Largest Manufacturer factory sales D-Lysine hydrochloride CAS 7274-88-6

Cas:7274-88-6

Min.Order:500 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Lorcaserin(856681-05-5)is an orally administered agent and a selective 5-HT2C receptor agonist for the treatment of obesity. It had been approved for marketing in US by FDA on 27 June in 2012. In clinical studies, lorcaserin h

D-Lysine Hydrochloride

Cas:7274-88-6

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

D-Lysine Hydrochloride

Cas:7274-88-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

D-Lysine monohydrochloride

Cas:7274-88-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fonlynn Health Technology Co., Ltd.

Packing: According to customer requirements Delivery time: In stock or depands Port of shipment: Ningbo/Shanghai/Qingdao OEM/ODM:Welcome Sample:We can offer our existing samples at once Transportation:Express/Sea/Air Port:Ningbo/Shanghai/Qingd

D-Lysine hydrochloride

Cas:7274-88-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality D-Lysine Hydrochloride

Cas:7274-88-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

hangzhou verychem science and technology co.ltd

Hangzhou Verychem Science And Technology Co. Ltd. was set up in year 2004, it’s a young but fast growing company. In the twelve years history, it invested two pharmaceutical raw material production plants, one researching company, and several

D-Lysine Hydrochloride

Cas:7274-88-6

Min.Order:1 Metric Ton

FOB Price: $30.0

Type:Manufacturers

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

High purity D-Lysine hydrochloride 7274-88-6 in stock immediately delivery good supplierAppearance:Powder Storage:Dry and ventilated Package:according to customers' requirements Application:APIs Transportation:By air(EMS or EUB or FedEx or TNT ect...

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

D-Lysine hydrochloride

Cas:7274-88-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

2,2-dimethoxy-propane
77-76-9

2,2-dimethoxy-propane

D-lysine methyl ester bis-hydrochloride

D-lysine methyl ester bis-hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In methanol at 20℃; for 15h; Reflux;95%
4-phenylazobenzoyl chloride
104-24-5

4-phenylazobenzoyl chloride

D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

bis-D-lysine

bis-D-lysine

Conditions
ConditionsYield
With sodium hydroxide In 1,4-dioxane64%
2,5-dioxopyrrolidin-1-yl 6-(((tert-butyldimethylsilyl)oxy)methyl)nicotinate
1277191-84-0

2,5-dioxopyrrolidin-1-yl 6-(((tert-butyldimethylsilyl)oxy)methyl)nicotinate

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide
82911-69-1

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

(R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-6-(6-(((tert-butyldimethylsilyl)oxy)methyl)nicotinamido)hexanoic acid
1277191-85-1

(R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-6-(6-(((tert-butyldimethylsilyl)oxy)methyl)nicotinamido)hexanoic acid

Conditions
ConditionsYield
Stage #1: D-lysine hydrochloride With copper(ll) sulfate pentahydrate; sodium hydrogencarbonate In water for 2h; Reflux;
Stage #2: 2,5-dioxopyrrolidin-1-yl 6-(((tert-butyldimethylsilyl)oxy)methyl)nicotinate In N,N-dimethyl-formamide at 0 - 20℃; for 16h;
Stage #3: N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide Further stages;
62%
palmitic acid N-succinimide ester
14464-31-4

palmitic acid N-succinimide ester

D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

Pam-DLys(Pam)-OH
870789-29-0

Pam-DLys(Pam)-OH

Conditions
ConditionsYield
Stage #1: palmitic acid N-succinimide ester; D-lysine hydrochloride With sodium carbonate In 1,4-dioxane at 20℃; for 48h;
Stage #2: With hydrogenchloride In 1,4-dioxane; water
61%
D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

acryloyl chloride
814-68-6

acryloyl chloride

(R)-6-acrylamido-2-aminohexanoic acid

(R)-6-acrylamido-2-aminohexanoic acid

Conditions
ConditionsYield
With copper(ll) sulfate pentahydrate; sodium carbonate; sodium hydroxide In water at 0 - 20℃; for 4h; Inert atmosphere;45.3%
D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

(R)-3-amino-azepan-2-one
28957-33-7

(R)-3-amino-azepan-2-one

Conditions
ConditionsYield
With hexamethyldisilazan In toluene for 168h; Heating / reflux;15%
Stage #1: D-lysine hydrochloride With thionyl chloride In methanol at -60 - 20℃; for 12h;
Stage #2: With sodium methylate In methanol for 4h; Reflux;
Multi-step reaction with 2 steps
1: hydrogenchloride / 3 h / Reflux
2: sodium methylate / methanol / 4 h / Reflux
View Scheme
tert-butyl fluoroformate
18595-34-1

tert-butyl fluoroformate

D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

Nε-(tert-butoxycarbonyl)-D-lysine
31202-69-4

Nε-(tert-butoxycarbonyl)-D-lysine

Conditions
ConditionsYield
(i) CuCO3*Cu(OH)2, (ii) aq. NaOH, NaHCO3, dioxane; Multistep reaction;
2,2-dimethylpropanoic anhydride
1538-75-6

2,2-dimethylpropanoic anhydride

2-methyl-1-nitroisourea
57538-27-9

2-methyl-1-nitroisourea

D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

Nα-tert-butoxycarbonyl-NG-nitro-D-homoarginine
132718-70-8

Nα-tert-butoxycarbonyl-NG-nitro-D-homoarginine

Conditions
ConditionsYield
Yield given. Multistep reaction;
D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

benzyl chloroformate
501-53-1

benzyl chloroformate

(R)-2-amino-6-(((benzyloxy)carbonyl)amino)hexanoic acid
34404-32-5, 1155-64-2, 32302-83-3

(R)-2-amino-6-(((benzyloxy)carbonyl)amino)hexanoic acid

Conditions
ConditionsYield
With copper (II) carbonate hydroxide; sodium hydroxide 1.) H2O, reflux, 2.5 h, 2.) RT, overnight; Yield given. Multistep reaction;
acetic anhydride
108-24-7

acetic anhydride

D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

Nε-acetyl-lysine
51621-57-9

Nε-acetyl-lysine

Conditions
ConditionsYield
With TEA 1.) H2O, reflux, 30 min, 2.) H2O, MeOH, a) 0 deg C, 1.5 h, b) RT, 1 h; Yield given. Multistep reaction;
D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

benzaldehyde
100-52-7

benzaldehyde

Nε-benzylidene-D-lysine

Nε-benzylidene-D-lysine

Conditions
ConditionsYield
With lithium hydroxide at 0℃;
D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

Nα-carbobenzoxy-D-lysine
70671-54-4

Nα-carbobenzoxy-D-lysine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: aq. LiOH / 0 °C
2.1: aq. NaOH / ethanol / 0.33 h / -10 - 20 °C
2.2: HCl / ethanol / 0.17 h / 50 °C
View Scheme
D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

(R)-3-Benzyloxycarbonylamino-7-hydroxy-heptanoic acid methyl ester

(R)-3-Benzyloxycarbonylamino-7-hydroxy-heptanoic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: aq. LiOH / 0 °C
2.1: aq. NaOH / ethanol / 0.33 h / -10 - 20 °C
2.2: HCl / ethanol / 0.17 h / 50 °C
3.1: NaNO2; AcOH / 6 h / 40 °C
4.1: Et3N; isobutyl chloroformate / tetrahydrofuran / 1 h / -25 - -10 °C
4.2: tetrahydrofuran; diethyl ether / -10 - 20 °C
5.1: PhCO2Ag; Et3N / -25 - 20 °C
6.1: K2CO3 / methanol / 6 h / 0 °C
View Scheme
D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

Acetic acid (R)-5-benzyloxycarbonylamino-7-diazo-6-oxo-heptyl ester

Acetic acid (R)-5-benzyloxycarbonylamino-7-diazo-6-oxo-heptyl ester

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: aq. LiOH / 0 °C
2.1: aq. NaOH / ethanol / 0.33 h / -10 - 20 °C
2.2: HCl / ethanol / 0.17 h / 50 °C
3.1: NaNO2; AcOH / 6 h / 40 °C
4.1: Et3N; isobutyl chloroformate / tetrahydrofuran / 1 h / -25 - -10 °C
4.2: tetrahydrofuran; diethyl ether / -10 - 20 °C
View Scheme
D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

(R)-6-Acetoxy-2-benzyloxycarbonylamino-hexanoic acid

(R)-6-Acetoxy-2-benzyloxycarbonylamino-hexanoic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: aq. LiOH / 0 °C
2.1: aq. NaOH / ethanol / 0.33 h / -10 - 20 °C
2.2: HCl / ethanol / 0.17 h / 50 °C
3.1: NaNO2; AcOH / 6 h / 40 °C
View Scheme
D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

(R)-7-Acetoxy-3-benzyloxycarbonylamino-heptanoic acid methyl ester

(R)-7-Acetoxy-3-benzyloxycarbonylamino-heptanoic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: aq. LiOH / 0 °C
2.1: aq. NaOH / ethanol / 0.33 h / -10 - 20 °C
2.2: HCl / ethanol / 0.17 h / 50 °C
3.1: NaNO2; AcOH / 6 h / 40 °C
4.1: Et3N; isobutyl chloroformate / tetrahydrofuran / 1 h / -25 - -10 °C
4.2: tetrahydrofuran; diethyl ether / -10 - 20 °C
5.1: PhCO2Ag; Et3N / -25 - 20 °C
View Scheme
D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

(S)-2-[((2R,3R)-3-Benzyloxycarbonylamino-7-hydroxy-2-methyl-heptanoyl)-methyl-amino]-3-methyl-butyric acid methyl ester

(S)-2-[((2R,3R)-3-Benzyloxycarbonylamino-7-hydroxy-2-methyl-heptanoyl)-methyl-amino]-3-methyl-butyric acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 11 steps
1.1: aq. LiOH / 0 °C
2.1: aq. NaOH / ethanol / 0.33 h / -10 - 20 °C
2.2: HCl / ethanol / 0.17 h / 50 °C
3.1: NaNO2; AcOH / 6 h / 40 °C
4.1: Et3N; isobutyl chloroformate / tetrahydrofuran / 1 h / -25 - -10 °C
4.2: tetrahydrofuran; diethyl ether / -10 - 20 °C
5.1: PhCO2Ag; Et3N / -25 - 20 °C
6.1: K2CO3 / methanol / 6 h / 0 °C
7.1: iPr2NEt / CH2Cl2 / 5 h / 20 °C
8.1: LDA; LiCl / tetrahydrofuran / -78 °C
9.1: LiOH*H2O / tetrahydrofuran; methanol; H2O / 0 - 20 °C
10.1: iPr2NEt; 1-hydroxy-7-azabenzotriazole; 2-bromo-1-ethylpyridinium tetrafluoroborate / CH2Cl2 / -25 - 20 °C
11.1: TFA / CH2Cl2 / 0 °C
View Scheme
D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

(R)-3-Benzyloxycarbonylamino-7-(2-trimethylsilanyl-ethoxymethoxy)-heptanoic acid methyl ester

(R)-3-Benzyloxycarbonylamino-7-(2-trimethylsilanyl-ethoxymethoxy)-heptanoic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: aq. LiOH / 0 °C
2.1: aq. NaOH / ethanol / 0.33 h / -10 - 20 °C
2.2: HCl / ethanol / 0.17 h / 50 °C
3.1: NaNO2; AcOH / 6 h / 40 °C
4.1: Et3N; isobutyl chloroformate / tetrahydrofuran / 1 h / -25 - -10 °C
4.2: tetrahydrofuran; diethyl ether / -10 - 20 °C
5.1: PhCO2Ag; Et3N / -25 - 20 °C
6.1: K2CO3 / methanol / 6 h / 0 °C
7.1: iPr2NEt / CH2Cl2 / 5 h / 20 °C
View Scheme
D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

(2R,3R)-3-Benzyloxycarbonylamino-2-methyl-7-(2-trimethylsilanyl-ethoxymethoxy)-heptanoic acid methyl ester
790302-28-2

(2R,3R)-3-Benzyloxycarbonylamino-2-methyl-7-(2-trimethylsilanyl-ethoxymethoxy)-heptanoic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1.1: aq. LiOH / 0 °C
2.1: aq. NaOH / ethanol / 0.33 h / -10 - 20 °C
2.2: HCl / ethanol / 0.17 h / 50 °C
3.1: NaNO2; AcOH / 6 h / 40 °C
4.1: Et3N; isobutyl chloroformate / tetrahydrofuran / 1 h / -25 - -10 °C
4.2: tetrahydrofuran; diethyl ether / -10 - 20 °C
5.1: PhCO2Ag; Et3N / -25 - 20 °C
6.1: K2CO3 / methanol / 6 h / 0 °C
7.1: iPr2NEt / CH2Cl2 / 5 h / 20 °C
8.1: LDA; LiCl / tetrahydrofuran / -78 °C
View Scheme
D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

(2R,3R)-3-Benzyloxycarbonylamino-2-methyl-7-(2-trimethylsilanyl-ethoxymethoxy)-heptanoic acid

(2R,3R)-3-Benzyloxycarbonylamino-2-methyl-7-(2-trimethylsilanyl-ethoxymethoxy)-heptanoic acid

Conditions
ConditionsYield
Multi-step reaction with 9 steps
1.1: aq. LiOH / 0 °C
2.1: aq. NaOH / ethanol / 0.33 h / -10 - 20 °C
2.2: HCl / ethanol / 0.17 h / 50 °C
3.1: NaNO2; AcOH / 6 h / 40 °C
4.1: Et3N; isobutyl chloroformate / tetrahydrofuran / 1 h / -25 - -10 °C
4.2: tetrahydrofuran; diethyl ether / -10 - 20 °C
5.1: PhCO2Ag; Et3N / -25 - 20 °C
6.1: K2CO3 / methanol / 6 h / 0 °C
7.1: iPr2NEt / CH2Cl2 / 5 h / 20 °C
8.1: LDA; LiCl / tetrahydrofuran / -78 °C
9.1: LiOH*H2O / tetrahydrofuran; methanol; H2O / 0 - 20 °C
View Scheme
D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

(S)-2-{[(2R,3R)-3-((S)-2-tert-Butoxycarbonylamino-3-methyl-butyrylamino)-2-methyl-7-oxo-heptanoyl]-methyl-amino}-3-methyl-butyric acid methyl ester

(S)-2-{[(2R,3R)-3-((S)-2-tert-Butoxycarbonylamino-3-methyl-butyrylamino)-2-methyl-7-oxo-heptanoyl]-methyl-amino}-3-methyl-butyric acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 14 steps
1.1: aq. LiOH / 0 °C
2.1: aq. NaOH / ethanol / 0.33 h / -10 - 20 °C
2.2: HCl / ethanol / 0.17 h / 50 °C
3.1: NaNO2; AcOH / 6 h / 40 °C
4.1: Et3N; isobutyl chloroformate / tetrahydrofuran / 1 h / -25 - -10 °C
4.2: tetrahydrofuran; diethyl ether / -10 - 20 °C
5.1: PhCO2Ag; Et3N / -25 - 20 °C
6.1: K2CO3 / methanol / 6 h / 0 °C
7.1: iPr2NEt / CH2Cl2 / 5 h / 20 °C
8.1: LDA; LiCl / tetrahydrofuran / -78 °C
9.1: LiOH*H2O / tetrahydrofuran; methanol; H2O / 0 - 20 °C
10.1: iPr2NEt; 1-hydroxy-7-azabenzotriazole; 2-bromo-1-ethylpyridinium tetrafluoroborate / CH2Cl2 / -25 - 20 °C
11.1: TFA / CH2Cl2 / 0 °C
12.1: aq. HCl; H2 / Pd/C / methanol / 20 °C
13.1: HOBt; EDCI; N-methylmorpholine / CH2Cl2 / 0 - 20 °C
14.1: DMSO; oxalyl chloride; iPr2NEt / CH2Cl2 / -78 - -55 °C
View Scheme
D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

(S)-2-[((2R,3R)-3-Amino-7-hydroxy-2-methyl-heptanoyl)-methyl-amino]-3-methyl-butyric acid methyl ester; hydrochloride

(S)-2-[((2R,3R)-3-Amino-7-hydroxy-2-methyl-heptanoyl)-methyl-amino]-3-methyl-butyric acid methyl ester; hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 12 steps
1.1: aq. LiOH / 0 °C
2.1: aq. NaOH / ethanol / 0.33 h / -10 - 20 °C
2.2: HCl / ethanol / 0.17 h / 50 °C
3.1: NaNO2; AcOH / 6 h / 40 °C
4.1: Et3N; isobutyl chloroformate / tetrahydrofuran / 1 h / -25 - -10 °C
4.2: tetrahydrofuran; diethyl ether / -10 - 20 °C
5.1: PhCO2Ag; Et3N / -25 - 20 °C
6.1: K2CO3 / methanol / 6 h / 0 °C
7.1: iPr2NEt / CH2Cl2 / 5 h / 20 °C
8.1: LDA; LiCl / tetrahydrofuran / -78 °C
9.1: LiOH*H2O / tetrahydrofuran; methanol; H2O / 0 - 20 °C
10.1: iPr2NEt; 1-hydroxy-7-azabenzotriazole; 2-bromo-1-ethylpyridinium tetrafluoroborate / CH2Cl2 / -25 - 20 °C
11.1: TFA / CH2Cl2 / 0 °C
12.1: aq. HCl; H2 / Pd/C / methanol / 20 °C
View Scheme
D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

(S)-2-{[(2R,3R)-3-((S)-2-tert-Butoxycarbonylamino-3-methyl-butyrylamino)-7-hydroxy-2-methyl-heptanoyl]-methyl-amino}-3-methyl-butyric acid methyl ester
790302-31-7

(S)-2-{[(2R,3R)-3-((S)-2-tert-Butoxycarbonylamino-3-methyl-butyrylamino)-7-hydroxy-2-methyl-heptanoyl]-methyl-amino}-3-methyl-butyric acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 13 steps
1.1: aq. LiOH / 0 °C
2.1: aq. NaOH / ethanol / 0.33 h / -10 - 20 °C
2.2: HCl / ethanol / 0.17 h / 50 °C
3.1: NaNO2; AcOH / 6 h / 40 °C
4.1: Et3N; isobutyl chloroformate / tetrahydrofuran / 1 h / -25 - -10 °C
4.2: tetrahydrofuran; diethyl ether / -10 - 20 °C
5.1: PhCO2Ag; Et3N / -25 - 20 °C
6.1: K2CO3 / methanol / 6 h / 0 °C
7.1: iPr2NEt / CH2Cl2 / 5 h / 20 °C
8.1: LDA; LiCl / tetrahydrofuran / -78 °C
9.1: LiOH*H2O / tetrahydrofuran; methanol; H2O / 0 - 20 °C
10.1: iPr2NEt; 1-hydroxy-7-azabenzotriazole; 2-bromo-1-ethylpyridinium tetrafluoroborate / CH2Cl2 / -25 - 20 °C
11.1: TFA / CH2Cl2 / 0 °C
12.1: aq. HCl; H2 / Pd/C / methanol / 20 °C
13.1: HOBt; EDCI; N-methylmorpholine / CH2Cl2 / 0 - 20 °C
View Scheme
D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

(S)-2-{[(2R,3R)-3-Benzyloxycarbonylamino-2-methyl-7-(2-trimethylsilanyl-ethoxymethoxy)-heptanoyl]-methyl-amino}-3-methyl-butyric acid methyl ester
790302-29-3

(S)-2-{[(2R,3R)-3-Benzyloxycarbonylamino-2-methyl-7-(2-trimethylsilanyl-ethoxymethoxy)-heptanoyl]-methyl-amino}-3-methyl-butyric acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 10 steps
1.1: aq. LiOH / 0 °C
2.1: aq. NaOH / ethanol / 0.33 h / -10 - 20 °C
2.2: HCl / ethanol / 0.17 h / 50 °C
3.1: NaNO2; AcOH / 6 h / 40 °C
4.1: Et3N; isobutyl chloroformate / tetrahydrofuran / 1 h / -25 - -10 °C
4.2: tetrahydrofuran; diethyl ether / -10 - 20 °C
5.1: PhCO2Ag; Et3N / -25 - 20 °C
6.1: K2CO3 / methanol / 6 h / 0 °C
7.1: iPr2NEt / CH2Cl2 / 5 h / 20 °C
8.1: LDA; LiCl / tetrahydrofuran / -78 °C
9.1: LiOH*H2O / tetrahydrofuran; methanol; H2O / 0 - 20 °C
10.1: iPr2NEt; 1-hydroxy-7-azabenzotriazole; 2-bromo-1-ethylpyridinium tetrafluoroborate / CH2Cl2 / -25 - 20 °C
View Scheme
D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

(R)-6-benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoic acid
55878-47-2

(R)-6-benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.) basic copper carbonate, 2.) NaOH / 1.) H2O, reflux, 2.5 h, 2.) RT, overnight
2: 91 percent / aq. NaOH / 2-methyl-propan-2-ol / Ambient temperature
View Scheme
D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

Boc-D-Lys-OH
106719-44-2

Boc-D-Lys-OH

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1.) basic copper carbonate, 2.) NaOH / 1.) H2O, reflux, 2.5 h, 2.) RT, overnight
2: 91 percent / aq. NaOH / 2-methyl-propan-2-ol / Ambient temperature
3: H2 / 5percent Pd/C / methanol; H2O / 24 h / 2585.7 Torr
View Scheme
D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

Nα-tert-butyloxycarbonyl-Nε-nicotinoyl-D-lysine
122546-52-5

Nα-tert-butyloxycarbonyl-Nε-nicotinoyl-D-lysine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 1.) basic copper carbonate, 2.) NaOH / 1.) H2O, reflux, 2.5 h, 2.) RT, overnight
2: 91 percent / aq. NaOH / 2-methyl-propan-2-ol / Ambient temperature
3: H2 / 5percent Pd/C / methanol; H2O / 24 h / 2585.7 Torr
4: dimethylformamide / 120 h / Ambient temperature
View Scheme
(9H-fluoren-9-yl)methyl azidoformate
28920-44-7

(9H-fluoren-9-yl)methyl azidoformate

D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

N,N'-bis-(9-fluorenylmethyloxycarbonyl)-D-lysine
75932-02-4

N,N'-bis-(9-fluorenylmethyloxycarbonyl)-D-lysine

Conditions
ConditionsYield
In hexane; water; sodium carbonate; acetone
benzyl bromide
100-39-0

benzyl bromide

D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

(R)-benzyl 2,6-bis(dibenzylamino)hexanoate

(R)-benzyl 2,6-bis(dibenzylamino)hexanoate

Conditions
ConditionsYield
Stage #1: benzyl bromide; D-lysine hydrochloride With potassium carbonate In ethanol at 60℃; for 96h;
Stage #2: In ethanol
D-lysine hydrochloride
7274-88-6

D-lysine hydrochloride

C26H30F6N2O5

C26H30F6N2O5

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sulfuric acid / water / 20 - 30 °C
1.2: 120 °C / 36228.6 Torr / Autoclave; Sealed tube
2.1: N-ethyl-N,N-diisopropylamine / dichloromethane-d2 / 2 h / 20 °C
View Scheme
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