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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

4-Bromo-2-fluorobenzyl bromide Manufacturer/High quality/Best price/In stock

Cas:76283-09-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2-Fluoride-4-Bromine Bromine Benzyl supplier in China

Cas:76283-09-5

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

4-bromo-1-(bromomethyl)-2-fluorobenzene CAS NO.76283-09-5

Cas:76283-09-5

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

4-Bromo-2-fluorobenzyl bromide

Cas:76283-09-5

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

4-Bromo-2-Fluorobenzyl Bromide

Cas:76283-09-5

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-Bromo-2-fluorobenzyl bromide

Cas:76283-09-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

4-Bromo-2-fluorobenzyl bromide

Cas:76283-09-5

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 76283-09-5 with best quality

Cas:76283-09-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

4-Bromo-2-fluorobenzyl bromide 76283-09-5

Cas:76283-09-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

4-Bromo-2-fluorobenzyl bromide CAS:76283-09-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality or

4-Bromo-2-fluorobenzyl bromide CAS:76283-09-5

Cas:76283-09-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

4-Bromo-2-fluorobenzyl bromide

Cas:76283-09-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:76283-09-5

Cas:76283-09-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2-fluoride-4-bromine bromine benzyl

Cas:76283-09-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2-Fluoro-4-bromobenzyl bromide

Cas:76283-09-5

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

4-Bromo-2-fluorobenzyl bromide

Cas:76283-09-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-Fluoro-4-bromobenzyl bromide

Cas:76283-09-5

Min.Order:0 Metric Ton

Negotiable

Type:Other

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Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products 4-Bromo-2-fluorobenzyl bromide

Cas:76283-09-5

Min.Order:100 Gram

Negotiable

Type:Other

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2-Fluoride-4-Bromine Bromine Benzyl

Cas:76283-09-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

CAS NO:76283-09-5 4-Bromo-2-fluorobenzyl bromideAppearance:powder Storage:store in cool, dry place Package:according to customers' requirements Application:76283-09-5 Transportation:By air(EMS or EUB or FedEx or TNT ect...) or by sea(FOB or CIF or C

CAS NO:76283-09-5 4-Bromo-2-fluorobenzyl bromide

Cas:76283-09-5

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

Product Name: 4-Bromo-2-fluorobenzyl bromide Synonyms: 4-BROMO-2-FLUOROBENZYL BROMIDE;4-BROMO-1-(BROMOMETHYL)-2-FLUORO-BENZENE;2-FLUORO-4-BROMOBENZYL BROMIDE;4-Bromo-1-Fluorobenzyl Bromide;4,α-dibromo-2-fluorotoluene;à,4-dibromo-2-flu

4-Bromo-2-fluorobenzyl bromide 76283-09-5

Cas:76283-09-5

Min.Order:1 Kilogram

FOB Price: $300.0

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

4-Bromo-2-fluorobenzyl bromide Basic information Product Name: 4-Bromo-2-fluorobenzyl bromide Synonyms: 4-BROMO-2-FLUOROBENZYL BROMIDE;4-BROMO-1-(BROMOMETHYL)-2-FLUORO-BENZENE;2-FLUORO-4-BROMOBENZYL BROMIDE;4-Bromo-1-Fluorobenzyl Bromide;4,&al

4-Bromo-2-fluorobenzyl bromide

Cas:76283-09-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

4-Bromo-2-fluorobenzyl bromide

Cas:76283-09-5

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

4-Bromo-2-fluorobenzyl bromide

Cas:76283-09-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

SAGECHEM/2-Fluoro-4-bromobenzyl bromide

Cas:76283-09-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Beijing Greenchem Technology Co.,Ltd. ( Panjin Greenchem Technology Co.Ltd .)

Capability on chemical synthesis1. Beijing High-Tech Enterprises2. Strong R&D Team3. 8 years of experiences in R & D of high-tech Catalyst;4. 5000 production techniques, 69 items of national patents, and 360 kinds of products on sales;5. The producti

2-Fluoro-4-bromobenzyl bromide

Cas:76283-09-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

4-Bromo-2-fluorobenzyl bromide

Cas:76283-09-5

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

CAS NO:76283-09-5 4-Bromo-2-fluorobenzyl bromide

Cas:76283-09-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

4-Bromo-2-Fluorobenzyl Bromide cas no. 76283-09-5 98%

Cas:76283-09-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

2-Fluoro-4-bromobenzyl bromide

Cas:76283-09-5

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

4-BroMo-1-(broMoMethyl)-2-fluorobenzene

Cas:76283-09-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

4-bromo-2-fluorobenzyl alcohol
188582-62-9

4-bromo-2-fluorobenzyl alcohol

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

Conditions
ConditionsYield
With hydrogen bromide at 100℃; for 0.166667h;91%
2-fluoro-4-bromotoluene
51436-99-8

2-fluoro-4-bromotoluene

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

Conditions
ConditionsYield
With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) In tetrachloromethane at 100℃; for 13h;89%
With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) In tetrachloromethane at 100℃; for 13h;89%
With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) In tetrachloromethane for 4h; Reflux; Inert atmosphere;53%
4-bromo-2-fluorobenzaldehyde
57848-46-1

4-bromo-2-fluorobenzaldehyde

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium tetrahydroborate / methanol / 0.5 h / 20 °C
2: hydrogen bromide / 0.17 h / 100 °C
View Scheme
sodium cyanide
773837-37-9

sodium cyanide

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

(4-bromo-2-fluorophenyl)acetonitrile
114897-91-5

(4-bromo-2-fluorophenyl)acetonitrile

Conditions
ConditionsYield
In ethanol; water at 100℃; for 8.5h;100%
In DMF (N,N-dimethyl-formamide); water at 70℃; for 1h;99%
In ethanol at 60℃; for 12h; Solvent; Temperature; Inert atmosphere;99%
4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

dimethyl amine
124-40-3

dimethyl amine

N,N-dimethyl-4-bromo-2-fluorobenzylamine
1159976-88-1

N,N-dimethyl-4-bromo-2-fluorobenzylamine

Conditions
ConditionsYield
With potassium carbonate In water at 0 - 20℃; for 0.166667h;100%
methyl 3-hydroxybenzoate
19438-10-9

methyl 3-hydroxybenzoate

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

3-(4-bromo-2-fluoro-benzyloxy)-benzoic acid methyl ester

3-(4-bromo-2-fluoro-benzyloxy)-benzoic acid methyl ester

Conditions
ConditionsYield
Stage #1: methyl 3-hydroxybenzoate With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: 4-bromo-2-fluorobenzyl bromide In N,N-dimethyl-formamide at 20℃;
99%
Stage #1: methyl 3-hydroxybenzoate With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: 4-bromo-2-fluorobenzyl bromide In N,N-dimethyl-formamide at 80℃;
sodium cyanide
143-33-9

sodium cyanide

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

(4-bromo-2-fluorophenyl)acetonitrile
114897-91-5

(4-bromo-2-fluorophenyl)acetonitrile

Conditions
ConditionsYield
In water; N,N-dimethyl-formamide at 70℃; for 1h;99%
In dimethyl sulfoxide at 20℃; for 4h;96%
In DMF (N,N-dimethyl-formamide); water at 70℃; for 3h;46%
In water; N,N-dimethyl-formamide at 70℃; for 1h;
2-chloro-1H-benzoimidazole
4857-06-1

2-chloro-1H-benzoimidazole

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

1-(4-bromo-2-fluoro-benzyl)-2-chloro-1H-benzoimidazole
388574-68-3

1-(4-bromo-2-fluoro-benzyl)-2-chloro-1H-benzoimidazole

Conditions
ConditionsYield
Stage #1: 2-chloro-1H-benzoimidazole With sodium hydride In N,N-dimethyl-formamide
Stage #2: 4-bromo-2-fluorobenzyl bromide In N,N-dimethyl-formamide at 20℃; Further stages.;
97%
ethyl 2-(7-chloro-1,2,3,4-tetrahydro-2,4-dioxoquinazoline-1-yl)acetate
112733-45-6

ethyl 2-(7-chloro-1,2,3,4-tetrahydro-2,4-dioxoquinazoline-1-yl)acetate

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

ethyl 2-[3-(4-bromo-2-fluorobenzyl)-7-chloro-1,2,3,4-tetrahydro-2,4-dioxoquinazoline-1-yl)acetate
112733-28-5

ethyl 2-[3-(4-bromo-2-fluorobenzyl)-7-chloro-1,2,3,4-tetrahydro-2,4-dioxoquinazoline-1-yl)acetate

Conditions
ConditionsYield
With potassium carbonate; acetic acid In methanol; water; acetone97%
With potassium carbonate In methanol; acetic acid; acetone96%
With potassium carbonate In acetone at 20℃; for 5h; Reflux; Large scale;95.1%
With potassium carbonate; acetic acid In methanol; water; acetone
2-pyrrolidinon
616-45-5

2-pyrrolidinon

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

1-[(4-bromo-2-fluorophenyl)methyl]-2-pyrrolidinone
1022931-60-7

1-[(4-bromo-2-fluorophenyl)methyl]-2-pyrrolidinone

Conditions
ConditionsYield
Stage #1: 2-pyrrolidinon With sodium hydride In N,N-dimethyl-formamide at 20℃; for 0.25h;
Stage #2: 4-bromo-2-fluorobenzyl bromide In N,N-dimethyl-formamide at 20℃;
97%
Stage #1: 2-pyrrolidinon With sodium hydride In N,N-dimethyl-formamide at 20℃; for 0.25h;
Stage #2: 4-bromo-2-fluorobenzyl bromide In N,N-dimethyl-formamide at 20℃;
85%
Stage #1: 2-pyrrolidinon With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 0.25h; Inert atmosphere;
Stage #2: 4-bromo-2-fluorobenzyl bromide In N,N-dimethyl-formamide; mineral oil at 20℃; for 5h;
85%
Stage #1: 2-pyrrolidinon With sodium hydride In N,N-dimethyl-formamide; mineral oil for 0.5h; Inert atmosphere;
Stage #2: 4-bromo-2-fluorobenzyl bromide In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; Inert atmosphere;
82%
C17H17N3O2
1415406-28-8

C17H17N3O2

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

1-(2-(4-bromo-2-fluorobenzyloxy)-2-(4-methoxyphenyl)ethyl)-4-phenyl-1H-1,2,3-triazole
1415406-43-7

1-(2-(4-bromo-2-fluorobenzyloxy)-2-(4-methoxyphenyl)ethyl)-4-phenyl-1H-1,2,3-triazole

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide for 2h;97%
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

4-(4-bromo-2-fluoro-benzyloxy)-3-methoxy-benzoic acid methyl ester

4-(4-bromo-2-fluoro-benzyloxy)-3-methoxy-benzoic acid methyl ester

Conditions
ConditionsYield
Stage #1: 4-hydroxy-3-methoxybenzoic acid methyl ester With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: 4-bromo-2-fluorobenzyl bromide In N,N-dimethyl-formamide at 20℃;
96%
4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

(4-bromo-2-fluorophenyl)acetonitrile
114897-91-5

(4-bromo-2-fluorophenyl)acetonitrile

Conditions
ConditionsYield
In dimethyl sulfoxide96%
With potassium cyanide In ethanol; water; ethyl acetate84%
With potassium cyanide In ethanol60%
ethyl 2-(7-chloro-1,2,3,4-tetrahydro-2,4-dioxoquinazoline-1-yl)acetate
112733-45-6

ethyl 2-(7-chloro-1,2,3,4-tetrahydro-2,4-dioxoquinazoline-1-yl)acetate

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

zenarestat

zenarestat

Conditions
ConditionsYield
With hydrogenchloride; potassium hydroxide; potassium carbonate In water; acetone96%
Multi-step reaction with 2 steps
1: potassium carbonate / acetone / 5 h / 20 °C / Reflux; Large scale
2: sodium hydroxide / methanol / 45 h / 30 - 40 °C / Reflux; Large scale
View Scheme
N-(diphenylmethylene)glycine tert-butyl ester
81477-94-3

N-(diphenylmethylene)glycine tert-butyl ester

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

tert-butyl 3-(4-bromo-2-fluorophenyl)-2-((diphenylmethylene)amino)propanoate
1040528-76-4

tert-butyl 3-(4-bromo-2-fluorophenyl)-2-((diphenylmethylene)amino)propanoate

Conditions
ConditionsYield
With tetrabutylammomium bromide; potassium hydroxide In toluene at 120℃; for 6h;96%
Stage #1: N-(diphenylmethylene)glycine tert-butyl ester With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 0.583333h;
Stage #2: 4-bromo-2-fluorobenzyl bromide In tetrahydrofuran at -78℃; for 0.583333h;
33%
Stage #1: N-(diphenylmethylene)glycine tert-butyl ester With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 0.416667h;
Stage #2: 4-bromo-2-fluorobenzyl bromide In tetrahydrofuran at -78 - 20℃; for 3.58333h;
Stage #3: With water; ammonium chloride In tetrahydrofuran
((1R,2R)-2-(1-(5-(methoxymethyl)pyrimidin-2-yl)piperidin-4-yl)cyclopropyl)methanol
1416366-90-9

((1R,2R)-2-(1-(5-(methoxymethyl)pyrimidin-2-yl)piperidin-4-yl)cyclopropyl)methanol

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

2-(4-((1R,2R)-2-(((4-bromo-2-fluorobenzyl)oxy)methyl)cyclopropyl)piperidin-1-yl)-5-(methoxymethyl)pyrimidine
1416366-91-0

2-(4-((1R,2R)-2-(((4-bromo-2-fluorobenzyl)oxy)methyl)cyclopropyl)piperidin-1-yl)-5-(methoxymethyl)pyrimidine

Conditions
ConditionsYield
Stage #1: ((1R,2R)-2-(1-(5-(methoxymethyl)pyrimidin-2-yl)piperidin-4-yl)cyclopropyl)methanol With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.0833333h;
Stage #2: 4-bromo-2-fluorobenzyl bromide In N,N-dimethyl-formamide at 0 - 20℃;
96%
Stage #1: ((1R,2R)-2-(1-(5-(methoxymethyl)pyrimidin-2-yl)piperidin-4-yl)cyclopropyl)methanol With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.0833333h;
Stage #2: 4-bromo-2-fluorobenzyl bromide In N,N-dimethyl-formamide; mineral oil at 0 - 20℃;
96%
saccharin sodium salt
128-44-9

saccharin sodium salt

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

2-<(4-bromo-2-fluorophenyl)methyl>benzoisothiazolin-3-one 1,1-dioxide
127511-40-4

2-<(4-bromo-2-fluorophenyl)methyl>benzoisothiazolin-3-one 1,1-dioxide

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 100℃; for 1h;95%
Dimethyl 5-hydroxyisophthalate
13036-02-7

Dimethyl 5-hydroxyisophthalate

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

5-(4-bromo-2-fluoro-benzyloxy)-isophthalic acid dimethyl ester

5-(4-bromo-2-fluoro-benzyloxy)-isophthalic acid dimethyl ester

Conditions
ConditionsYield
Stage #1: Dimethyl 5-hydroxyisophthalate With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: 4-bromo-2-fluorobenzyl bromide In N,N-dimethyl-formamide at 20℃;
95%
4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

methyl salicylate
119-36-8

methyl salicylate

2-(4-bromo-2-fluoro-benzyloxy)-benzoic acid methyl ester

2-(4-bromo-2-fluoro-benzyloxy)-benzoic acid methyl ester

Conditions
ConditionsYield
Stage #1: methyl salicylate With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: 4-bromo-2-fluorobenzyl bromide In N,N-dimethyl-formamide at 20℃;
95%
potassium cyanide
151-50-8

potassium cyanide

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

(4-bromo-2-fluorophenyl)acetonitrile
114897-91-5

(4-bromo-2-fluorophenyl)acetonitrile

Conditions
ConditionsYield
In ethanol; water at 60℃; for 2h;94%
In ethanol; water at 60℃; for 2h;94%
In ethanol; water at 60℃; for 2h;93%
In DMF (N,N-dimethyl-formamide); water at 40℃; for 3h;87%
In ethanol; water at 20℃;
(S)‐2‐nitro‐6,7‐dihydro‐5H‐imidazo[2,1‐b][1,3]oxazin‐6‐ol
187235-08-1

(S)‐2‐nitro‐6,7‐dihydro‐5H‐imidazo[2,1‐b][1,3]oxazin‐6‐ol

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

(6S)-6-[(4-bromo-2-fluorobenzyl)oxy]-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine
1188335-21-8

(6S)-6-[(4-bromo-2-fluorobenzyl)oxy]-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; Inert atmosphere;93%
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 3h; Inert atmosphere;93%
With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃;93%
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃;
C17H16N4O3

C17H16N4O3

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

1-(2-(4-bromo-2-fluorobenzyloxy)-2-(3-nitrophenyl)ethyl)-4-phenyl-1H-1,2,3-triazole
1415406-41-5

1-(2-(4-bromo-2-fluorobenzyloxy)-2-(3-nitrophenyl)ethyl)-4-phenyl-1H-1,2,3-triazole

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide for 2h;93%
methanol
67-56-1

methanol

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

4-bromo-2-fluoro-1-(methoxymethyl)benzene
95068-02-3

4-bromo-2-fluoro-1-(methoxymethyl)benzene

Conditions
ConditionsYield
With sodium methylate at 20℃; for 4.5h;93%
morpholine
110-91-8

morpholine

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

4-[(4-bromo-2-fluorophenyl)methyl]morpholine
338454-98-1

4-[(4-bromo-2-fluorophenyl)methyl]morpholine

Conditions
ConditionsYield
Stage #1: morpholine for 0.166667h;
Stage #2: 4-bromo-2-fluorobenzyl bromide at 60℃; for 8h;
92.95%
With potassium iodide In N,N-dimethyl-formamide at 60℃; for 13h;45%
With potassium iodide In N,N-dimethyl-formamide at 60℃; for 13h;45%
In acetonitrile at 20℃; for 16h;
3-piperidin-3-yl-1H-indole-2-carboxylic acid ethyl ester
1268716-42-2

3-piperidin-3-yl-1H-indole-2-carboxylic acid ethyl ester

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

3-[1-(4-bromo-2-fluoro-benzyl)-piperidin-3-yl]-1H-indole-2-carboxylic acid ethyl ester
1268716-44-4

3-[1-(4-bromo-2-fluoro-benzyl)-piperidin-3-yl]-1H-indole-2-carboxylic acid ethyl ester

Conditions
ConditionsYield
With triethylamine In 1,2-dichloro-ethane at 20℃; for 4h;92.1%
With triethylamine In 1,2-dichloro-ethane at 20℃; for 4h;
2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-indazole
885698-95-3

2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-indazole

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

4-(4-(bromomethyl)-3-fluorophenyl)-2-methyl-2H-indazole

4-(4-(bromomethyl)-3-fluorophenyl)-2-methyl-2H-indazole

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate In 1,2-dimethoxyethane at 50℃; for 1h; Microwave irradiation;92%
4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

4-Methoxybenzyl alcohol
105-13-5

4-Methoxybenzyl alcohol

4-bromo-2-fluoro-1-{[(4-methoxybenzyl)oxy]methyl}benzene
924312-28-7

4-bromo-2-fluoro-1-{[(4-methoxybenzyl)oxy]methyl}benzene

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃;91%
tributyltin chloride
1461-22-9

tributyltin chloride

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

(o-F,p-Br-benzyl)tributylstannane
174473-26-8

(o-F,p-Br-benzyl)tributylstannane

Conditions
ConditionsYield
With Zn; NH4Cl In tetrahydrofuran; water air; addn. of organotin (1 equiv.) to suspension of Zn-powder (2 equivs.) in satd. soln. of NH4Cl in H2O:THF, dropwise addn. of benzyl bromide (2 equivs.) with rate maintaining gentle reflux, stirring with cooling toroom temp. for 30 min; sepn. of org. layer, evapn., distillation (vac.); elem. anal.;91%
tert-butyl (1,3-cis)-N-(3-hydroxycyclobutyl)carbamate
389890-43-1

tert-butyl (1,3-cis)-N-(3-hydroxycyclobutyl)carbamate

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

tert-butyl ((1S,3S)-3-((4-bromo-2-fluorobenzyl)oxy)cyclobutyl)carbamate

tert-butyl ((1S,3S)-3-((4-bromo-2-fluorobenzyl)oxy)cyclobutyl)carbamate

Conditions
ConditionsYield
Stage #1: tert-butyl (1,3-cis)-N-(3-hydroxycyclobutyl)carbamate With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 1h;
Stage #2: 4-bromo-2-fluorobenzyl bromide In tetrahydrofuran; mineral oil at 20℃; for 8h;
91%
4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

O6-Demethyl-Donepezil
120013-56-1

O6-Demethyl-Donepezil

2-[(1-benzylpiperidin-4-yl)methyl]-6-[(4-bromo-2-fluorobenzyl)oxy-5-methoxy-2,3-dihydroinden-1-one]

2-[(1-benzylpiperidin-4-yl)methyl]-6-[(4-bromo-2-fluorobenzyl)oxy-5-methoxy-2,3-dihydroinden-1-one]

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃;91%
pyrrolidine
123-75-1

pyrrolidine

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

1-(4-bromo-2-fluorobenzyl)pyrrolidine

1-(4-bromo-2-fluorobenzyl)pyrrolidine

Conditions
ConditionsYield
Stage #1: pyrrolidine; 4-bromo-2-fluorobenzyl bromide In acetonitrile at 10 - 20℃; for 4h;
Stage #2: With sodium carbonate In water; acetonitrile
90%
In acetonitrile at 10 - 20℃; for 4h;90%
Stage #1: pyrrolidine With potassium carbonate In acetone at 20℃; for 0.25h;
Stage #2: 4-bromo-2-fluorobenzyl bromide In acetone at 20℃; for 1.33h;
3.4 g
4-cyclopropyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one hydrochloride
1375107-47-3

4-cyclopropyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one hydrochloride

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

9-[(4-bromo-2-fluorophenyl)methyl]-4-cyclopropyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
1429790-71-5

9-[(4-bromo-2-fluorophenyl)methyl]-4-cyclopropyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In acetonitrile at 125℃; for 0.416667h; Microwave irradiation;90%
With N-ethyl-N,N-diisopropylamine In acetonitrile at 125℃; for 0.333333h; Microwave irradiation;6.121 g

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