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NIGNXIA XINDACHANG TECHNOLOGY CO.,LTD

Donglian as a factory and supplier of aroma chemicals in China, We can provide different quantities of custom synthesis chemicals in food flavor scale more than fourteen years.in addition, our company has researched and developed four series

Methyl vanillate

Cas:3943-74-6

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Methyl vanillate Manufacturer/High quality/Best price/In stock

Cas:3943-74-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Methylvanillate with high purity

Cas:3943-74-6

Min.Order:1 Kilogram

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Type:Manufacturers

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ANQING CHICO PHARMACEUTICAL CO.,LTD.

High quality. Factory supply. In stock. Best price.1.Quick response within 24 hours;2.Best quality in your requirement;?3.We pay more attention on delivery time, and usually ship on time;4.Under the premise of safety and effectiveness, we can produce

Methyl vanillate

Cas:3943-74-6

Min.Order:0

Negotiable

Type:Trading Company

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Methyl Vanillate

Cas:3943-74-6

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-Hydroxy-3-methoxybenzoic acid methyl ester

Cas:3943-74-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Leader Biochemical Group

Methyl vanillate Chemical Properties Melting point 64-67 °C (lit.) Boiling point 285-287 °C (lit.) density 1.2481 (rough estimate) refractive index 1.4500 (estimate)

China Largest Factory & Manufacturer supply Methyl vanillate CAS 3943-74-6

Cas:3943-74-6

Min.Order:1 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

3943-74-6 Methyl vanillate Basic information Product Name: Methyl vanillate Synonyms: 4-HYDROXY-3-METHOXYBENZOIC ACID METHYL ESTER;METHYL 4-HYDROXY-3-METHOXYBENZOATE;METHYL VANILLATE;M

Methyl vanillate

Cas:3943-74-6

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be sent

Methyl vanillate

Cas:3943-74-6

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 3943-74-6 with competitive price

Cas:3943-74-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Methyl vanillate 3943-74-6

Cas:3943-74-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Methyl vanillate

Cas:3943-74-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:3943-74-6

Cas:3943-74-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Changchun Artel lmport and Export trade company

minimum order qty. 10 gram

Methyl vanillate CAS NO.3943-74-6

Cas:3943-74-6

Min.Order:10 Gram

Negotiable

Type:Trading Company

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Methyl Vanillate

Cas:3943-74-6

Min.Order:0

Negotiable

Type:Manufacturers

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Methyl vanillate

Cas:3943-74-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Methyl vanillate

Cas:3943-74-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou Lingrui Chemical Co.,Ltd.

our strengths: 1: Fast and guaranteed shipment (TNT;EMS;FEDEX;DHL;UPS;EUB, special line) 2: Various payment items accepted (Btc; MoneyGram; WU) 3: Valued package (Paraffin coating; Double aluminum foil bag; Vacuum packaging) 4: Efficient delivery

Methyl vanillate with lower price

Cas:3943-74-6

Min.Order:1 Gram

Negotiable

Type:Other

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and als

Methyl vanillate

Cas:3943-74-6

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h

Factory Supply Methyl vanillate

Cas:3943-74-6

Min.Order:0

Negotiable

Type:Other

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Siwei Development Group Ltd.

Product name: 4-Hydroxy-3-Methoxybenzoic Acid Methyl Ester CAS No.:3943-74-6 Molecule Formula:C9H10O4 Molecule Weight:182.17 Purity: 99.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standa

High Quality 4-Hydroxy-3-Methoxybenzoic Acid Methyl Ester

Cas:3943-74-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Methyl vanillate

Cas:3943-74-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Quality Manufacturer Methyl vanillate

Cas:3943-74-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Methylvanillate

Cas:3943-74-6

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

Methyl vanillate

Cas:3943-74-6

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

Methyl Vanillate

Cas:3943-74-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Methyl vanillate CAS NO.3943-74-6 CAS NO.3943-74-6

Cas:3943-74-6

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Methyl vanillate

Cas:3943-74-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

Methyl vanillate

Cas:3943-74-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

Methyl vanillate

Cas:3943-74-6

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Synthetic route

methanol
67-56-1

methanol

3-methoxy-4-hydroxybenzoic acid
121-34-6

3-methoxy-4-hydroxybenzoic acid

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

Conditions
ConditionsYield
With hydrogenchloride for 12h; Reflux;100%
With hydrogenchloride In diethyl ether Fischer-Speier Esterification; Reflux;100%
With thionyl chloride at 0 - 20℃; Inert atmosphere;100%
methyl 4-(benzyloxy)-3-methoxybenzoate
56441-97-5

methyl 4-(benzyloxy)-3-methoxybenzoate

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In various solvent(s) at 20℃; under 760 Torr; for 6h;95%
methanol
67-56-1

methanol

vanillin
121-33-5

vanillin

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

Conditions
ConditionsYield
With perchloric acid; sodium percarbonate; vanadia for 2h; Cooling;94%
With 2,2':6,2''-terpyridine; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; sodium acetate; sodium hydroxide at 90℃; for 24h; Green chemistry; chemoselective reaction;83%
With 1-(ferrocenylbutyl)-4-(3-methylimidazolium) tetrafluoroborate; iodine; potassium carbonate at 50 - 60℃; for 22h; Inert atmosphere;40%
With oxygen; methylene blue at 10 - 15℃; for 144h; Mechanism; Irradiation; also with EtOH; also without irradiation in the presence of p-toluenesulfonic acid;
With perchloric acid; dihydrogen peroxide; vanadia In water at 5℃; for 6h; oxidative esterification;83 % Chromat.
Trimethyl orthoacetate
1445-45-0

Trimethyl orthoacetate

3-methoxy-4-hydroxybenzoic acid
121-34-6

3-methoxy-4-hydroxybenzoic acid

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

Conditions
ConditionsYield
microwave irradiation;90%
3-methoxy-4-hydroxybenzoic acid
121-34-6

3-methoxy-4-hydroxybenzoic acid

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

Conditions
ConditionsYield
With sulfuric acid; sodium hydrogencarbonate; mercury In methanol; (2S)-N-methyl-1-phenylpropan-2-amine hydrate82%
methanol
67-56-1

methanol

carbon monoxide
201230-82-2

carbon monoxide

2-methoxy-phenol
90-05-1

2-methoxy-phenol

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

Conditions
ConditionsYield
With bis-triphenylphosphine-palladium(II) chloride; oxygen; potassium carbonate; potassium iodide at 100℃; under 6000.6 Torr; for 18h;76%
methanol
67-56-1

methanol

seguinoside E

seguinoside E

A

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

B

4-hydroxyphenyl β-D-apiofuranosyl-(1->2)-O-β-D-glucopyranoside

4-hydroxyphenyl β-D-apiofuranosyl-(1->2)-O-β-D-glucopyranoside

Conditions
ConditionsYield
With sodium hydroxide at 25℃; for 6h;A 64%
B n/a
(E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid
1135-24-6

(E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid

A

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

B

vanillin
121-33-5

vanillin

C

4-hydroxy-3-methoxybenzoylacetic acid
84272-48-0

4-hydroxy-3-methoxybenzoylacetic acid

D

1-(3-methoxy-4-hydroxyphenyl)ethanone
498-02-2

1-(3-methoxy-4-hydroxyphenyl)ethanone

Conditions
ConditionsYield
With salcomine; oxygen In methanol at 25℃; under 7600 Torr; for 72h;A 20%
B 16%
C n/a
D n/a
With salcomine; oxygen In methanol at 25℃; under 7600 Torr; for 72h; Product distribution; also with following CH2N2/ether action, other products;A 20%
B 16%
C n/a
D n/a
methyl 3-methoxybenzoate
5368-81-0

methyl 3-methoxybenzoate

A

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

B

3-methoxymethylsalicylate
6342-70-7

3-methoxymethylsalicylate

C

methyl 5-methoxy-2-hydroxybenzoate
2905-82-0

methyl 5-methoxy-2-hydroxybenzoate

Conditions
ConditionsYield
Stage #1: methyl 3-methoxybenzoate With 6,7-dichlorobenzo[d][1,2]dioxine-1,4-dione In chloroform at 50℃; for 24h;
Stage #2: With water; sodium hydrogencarbonate In methanol at 50℃; for 1h; Inert atmosphere; Overall yield = 55 %; regioselective reaction;
A 20%
B 18%
C 17%
3-methoxy-4-hydroxybenzoic acid
121-34-6

3-methoxy-4-hydroxybenzoic acid

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

methanol
67-56-1

methanol

2-methoxy-4-propenylphenol
97-54-1

2-methoxy-4-propenylphenol

acetic anhydride
108-24-7

acetic anhydride

A

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

B

Acetic acid 2-methoxy-4-[1-methoxy-2-(2-methoxy-4-propyl-phenoxy)-propyl]-phenyl ester
36831-66-0

Acetic acid 2-methoxy-4-[1-methoxy-2-(2-methoxy-4-propyl-phenoxy)-propyl]-phenyl ester

(E)-1-<(2RS,3SR)-2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-3-methyl-1-benzofuran-5-yl>-1-propene
2680-81-1, 23518-29-8, 23518-30-1, 51020-86-1, 64870-40-2, 69744-09-8, 72274-58-9, 72274-59-0, 83377-50-8, 88034-58-6, 127000-67-3

(E)-1-<(2RS,3SR)-2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-3-methyl-1-benzofuran-5-yl>-1-propene

D

vanillin
121-33-5

vanillin

Acetic acid 4-(2-hydroperoxy-1-methoxy-propyl)-2-methoxy-phenyl ester
138252-48-9

Acetic acid 4-(2-hydroperoxy-1-methoxy-propyl)-2-methoxy-phenyl ester

Acetic acid 4-(2-acetylperoxy-1-methoxy-propyl)-2-methoxy-phenyl ester
138252-52-5

Acetic acid 4-(2-acetylperoxy-1-methoxy-propyl)-2-methoxy-phenyl ester

Conditions
ConditionsYield
With pyridine; oxygen Mechanism; Product distribution; 1.) 10 -15 deg C, 5 d, methylene blue, irradiation, 2.) r.t., overnight; also with ethanol;
methyl 1-(3-bromopropyl)-3-methoxy-4-ketocyclohexa-2,5-diene-1-carboxylate
103669-14-3

methyl 1-(3-bromopropyl)-3-methoxy-4-ketocyclohexa-2,5-diene-1-carboxylate

A

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

methyl <3aα,7β,7aα>-6-keto-7-methoxy-1,2,3,6,7,7a-hexahydro-3aH-indene-3a-carboxylate

methyl <3aα,7β,7aα>-6-keto-7-methoxy-1,2,3,6,7,7a-hexahydro-3aH-indene-3a-carboxylate

methyl <3aα,7aα>-6-keto-5-methoxy-1,2,3,6,7,7a-hexahydro-3aH-indene-3a-carboxylate

methyl <3aα,7aα>-6-keto-5-methoxy-1,2,3,6,7,7a-hexahydro-3aH-indene-3a-carboxylate

Conditions
ConditionsYield
With tri-n-butyl-tin hydride In benzene Heating; Yields of byproduct given;
With tri-n-butyl-tin hydride In benzene Heating; Yield given;
Methyl ferulate
2309-07-1

Methyl ferulate

A

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

B

vanillin
121-33-5

vanillin

Conditions
ConditionsYield
With oxygen; salcomine In chloroform at 25℃; under 7500.6 Torr; for 48h; Product distribution; Mechanism; different phenols, solvents and reaction times;A 61 % Chromat.
B 39 % Chromat.
With oxygen; [N,N'-bis(salicylidene)ethane-1,2-diaminato]cobalt(II) In chloroform at 24.84℃; under 7500.75 Torr; for 48h; Product distribution;
hydrogenchloride
7647-01-0

hydrogenchloride

methanol
67-56-1

methanol

3-methoxy-4-hydroxybenzoic acid
121-34-6

3-methoxy-4-hydroxybenzoic acid

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

methyl (E)-[(2RS,3SR)-2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-3-methoxycarbonyl-1-benzofuran-5-yl]propenoate

methyl (E)-[(2RS,3SR)-2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-3-methoxycarbonyl-1-benzofuran-5-yl]propenoate

A

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

B

vanillin
121-33-5

vanillin

C

7-Methoxy-5-((E)-2-methoxycarbonyl-vinyl)-benzofuran-3-carboxylic acid methyl ester

7-Methoxy-5-((E)-2-methoxycarbonyl-vinyl)-benzofuran-3-carboxylic acid methyl ester

D

(E)-3-Hydroxy-2-[2-hydroxy-3-methoxy-5-((E)-2-methoxycarbonyl-vinyl)-phenyl]-3-(4-hydroxy-3-methoxy-phenyl)-acrylic acid methyl ester

(E)-3-Hydroxy-2-[2-hydroxy-3-methoxy-5-((E)-2-methoxycarbonyl-vinyl)-phenyl]-3-(4-hydroxy-3-methoxy-phenyl)-acrylic acid methyl ester

Conditions
ConditionsYield
With oxygen; [N,N'-bis(salicylidene)ethane-1,2-diaminato]cobalt(II) In chloroform at 24.84℃; under 7500.75 Torr; for 48h; Product distribution;
methyl 3,4-dimethoxybenzoate
2150-38-1

methyl 3,4-dimethoxybenzoate

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: diluted NaOH-solution
2: diluted hydrochloric acid / 160 - 170 °C / im geschlossenen Rohr
3: HCl
View Scheme
Veratric acid
93-07-2

Veratric acid

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: diluted hydrochloric acid / 160 - 170 °C / im geschlossenen Rohr
2: HCl
View Scheme
3-methoxy-4-hydroxybenzoic acid
121-34-6

3-methoxy-4-hydroxybenzoic acid

A

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

B

3-hydroxy-4-methoxybenzoate
6702-50-7

3-hydroxy-4-methoxybenzoate

methanol
67-56-1

methanol

2-(4-hydroxy-3-methoxyphenyl)-2-methoxyacetonitrile
1000180-41-5

2-(4-hydroxy-3-methoxyphenyl)-2-methoxyacetonitrile

A

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

B

C11H13NO4
1000180-45-9

C11H13NO4

Conditions
ConditionsYield
With manganese(IV) oxide; water for 24h; Title compound not separated from byproducts.;
2-(4-hydroxy-3-methoxyphenyl)-2-methoxyacetonitrile
1000180-41-5

2-(4-hydroxy-3-methoxyphenyl)-2-methoxyacetonitrile

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

Conditions
ConditionsYield
With manganese(IV) oxide; acetic acid In methanol; water for 24h;
methanol
67-56-1

methanol

lignin

lignin

A

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

B

methyl syringate
884-35-5

methyl syringate

C

vanillin
121-33-5

vanillin

D

syringic aldehyde
134-96-3

syringic aldehyde

Conditions
ConditionsYield
With oxygen; phosphomolybdic acid In water at 170℃; under 3825.38 Torr;
methanol
67-56-1

methanol

lignin

lignin

A

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

B

vanillin
121-33-5

vanillin

Conditions
ConditionsYield
With oxygen; phosphomolybdic acid In water at 170℃; under 3825.38 Torr;
methanol
67-56-1

methanol

lignin

lignin

A

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

B

2,4'-dihydroxy-3'-methoxyacetophenone
18256-48-9

2,4'-dihydroxy-3'-methoxyacetophenone

C

vanillin
121-33-5

vanillin

Conditions
ConditionsYield
phosphomolybdic acid In water at 170℃; under 7500.75 Torr; Inert atmosphere;
vanillin
121-33-5

vanillin

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: silver(l) oxide; sodium hydroxide / water / 3 h / 80 °C
2: sulfuric acid / 2.5 h / 100 °C / Autoclave
View Scheme
Multi-step reaction with 2 steps
1: recombinant aldehyde dehydrogenase from bovine lens; 1,4-dithio-D,L-threitol; water‐forming NADH oxidase from Streptococcus mutans; NAD / aq. phosphate buffer / 24 h / 40 °C / pH 8.5 / Green chemistry; Enzymatic reaction
2: methanol; ethyl acetate / 1 h / 30 °C
View Scheme
3-methoxy-4-hydroxybenzoic acid
121-34-6

3-methoxy-4-hydroxybenzoic acid

diazomethyl-trimethyl-silane
18107-18-1

diazomethyl-trimethyl-silane

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

Conditions
ConditionsYield
In methanol; ethyl acetate at 30℃; for 1h;
methanol
67-56-1

methanol

guaiacylglycerol-β-guaiacyl ether
7382-59-4

guaiacylglycerol-β-guaiacyl ether

A

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

B

2-methoxy-phenol
90-05-1

2-methoxy-phenol

Conditions
ConditionsYield
With oxygen; sodium hydroxide at 200℃; under 7500.75 Torr; for 10h; Catalytic behavior; Reagent/catalyst; Pressure; Temperature; Autoclave;A 23 %Chromat.
B 31 %Chromat.
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

allyl bromide
106-95-6

allyl bromide

methyl 3-methoxy-4-(2-propenoxy)benzoate
171002-53-2

methyl 3-methoxy-4-(2-propenoxy)benzoate

Conditions
ConditionsYield
With potassium carbonate In acetone at 40℃; for 16h; Inert atmosphere;100%
With potassium carbonate In N,N-dimethyl-formamide at 40℃; for 2h;95%
Stage #1: 4-hydroxy-3-methoxybenzoic acid methyl ester With sodium hydride In N,N-dimethyl-formamide at 20℃; for 2h; Metallation;
Stage #2: allyl bromide In N,N-dimethyl-formamide at 20℃; for 18h; Alkylation;
92%
With sodium hydride 1.) DMF, r.t., 2 h; 2.) r.t., 24 h; Multistep reaction;
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

trifluoromethylsulfonic anhydride
358-23-6

trifluoromethylsulfonic anhydride

3-methoxy-4-trifluoromethane-sulfonyloxy-benzoic acid methyl ester
175153-75-0

3-methoxy-4-trifluoromethane-sulfonyloxy-benzoic acid methyl ester

Conditions
ConditionsYield
With 2,4,6-trimethyl-pyridine In dichloromethane at -78 - 20℃; for 4h;100%
With pyridine In dichloromethane at 0℃; for 0.333333h;100%
With pyridine In dichloromethane at 0℃; for 4h;99%
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

benzyl bromide
100-39-0

benzyl bromide

methyl 4-(benzyloxy)-3-methoxybenzoate
56441-97-5

methyl 4-(benzyloxy)-3-methoxybenzoate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 3h;100%
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 3h;100%
With potassium carbonate In N,N-dimethyl-formamide at 100℃;100%
1,5-dibromo-pentane
111-24-0

1,5-dibromo-pentane

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

1',5'-bis<2-methoxy-(4-methoxycarbonyl)phenoxy>pentane
145325-42-4

1',5'-bis<2-methoxy-(4-methoxycarbonyl)phenoxy>pentane

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 75℃; for 3h; Inert atmosphere;100%
With potassium carbonate In N,N-dimethyl-formamide for 3h; Inert atmosphere;7.92 g
2-(prop-2-yn-1-yl)propane-1,3-diol
771430-70-7

2-(prop-2-yn-1-yl)propane-1,3-diol

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

4,4'-((2-(prop-2-yn-1-yl)propane-1,3-diyl)bis(oxy))bis(3-methoxybenzoic acid methyl ester)

4,4'-((2-(prop-2-yn-1-yl)propane-1,3-diyl)bis(oxy))bis(3-methoxybenzoic acid methyl ester)

Conditions
ConditionsYield
Stage #1: 4-hydroxy-3-methoxybenzoic acid methyl ester With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 0℃; for 0.583333h; Inert atmosphere;
Stage #2: 2-(prop-2-yn-1-yl)propane-1,3-diol In tetrahydrofuran at 0℃; for 1h; Inert atmosphere;
100%
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

methyl 4-(3-chloropropoxy)-3-methoxybenzoate
111627-40-8

methyl 4-(3-chloropropoxy)-3-methoxybenzoate

Conditions
ConditionsYield
With potassium carbonate; sodium chloride In acetone at 55 - 60℃; for 5h; Heating / reflux;99.5%
With potassium carbonate In acetone; acetonitrile at 75 - 79℃; for 5h; Heating / reflux;99.3%
With potassium chloride; potassium carbonate In acetone at 55 - 60℃; for 10h; Heating / reflux;98.2%
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

2,3,4,6-tetra-O-acetyl-D-allopyranosyl N-phenyltrifluoroacetimidate
1293384-39-0

2,3,4,6-tetra-O-acetyl-D-allopyranosyl N-phenyltrifluoroacetimidate

methyl 3-methoxy-4-(2,3,4,6-tetra-O-acetyl-β-D-allopyranosyloxy)benzoate
1293384-41-4

methyl 3-methoxy-4-(2,3,4,6-tetra-O-acetyl-β-D-allopyranosyloxy)benzoate

Conditions
ConditionsYield
With boron trifluoride diethyl etherate In dichloromethane at 0℃; for 2h; Molecular sieve;99%
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

1-Bromodocosane
6938-66-5

1-Bromodocosane

C31H54O4

C31H54O4

Conditions
ConditionsYield
Stage #1: 4-hydroxy-3-methoxybenzoic acid methyl ester With potassium carbonate at 80℃; for 0.5h;
Stage #2: 1-Bromodocosane at 70℃; for 15h;
99%
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

4-bromobutyric acid allyl ester
178215-45-7

4-bromobutyric acid allyl ester

C16H20O6

C16H20O6

Conditions
ConditionsYield
With potassium carbonate In acetone at 60℃; for 1.5h;99%
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

benzyl chloride
100-44-7

benzyl chloride

methyl 4-(benzyloxy)-3-methoxybenzoate
56441-97-5

methyl 4-(benzyloxy)-3-methoxybenzoate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 3h;98%
With potassium carbonate In acetonitrile at 90℃; for 2h; Inert atmosphere;97%
With potassium carbonate In acetonitrile at 20℃; for 8h; Inert atmosphere;81%
With potassium carbonate; potassium iodide In acetone Inert atmosphere; Reflux;57%
With potassium hydroxide
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

propargyl bromide
106-96-7

propargyl bromide

3-methoxy-4-(prop-2-yn-1-yloxy)benzoic acid methyl ester

3-methoxy-4-(prop-2-yn-1-yloxy)benzoic acid methyl ester

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide for 3h; Ambient temperature;98%
Stage #1: 4-hydroxy-3-methoxybenzoic acid methyl ester With potassium carbonate In N,N-dimethyl-formamide for 0.5h;
Stage #2: propargyl bromide In N,N-dimethyl-formamide at 25℃; for 2h;
95%
With potassium carbonate In N,N-dimethyl-formamide93%
2,3-dihydro-2H-furan
1191-99-7

2,3-dihydro-2H-furan

methanol
67-56-1

methanol

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

methyl (1R*,2R*,6R*,7R*)-11,11-dimethoxy-3-oxa-10-oxotricyclo[5.2.2.02,6]undec-8-en-8-carboxylate

methyl (1R*,2R*,6R*,7R*)-11,11-dimethoxy-3-oxa-10-oxotricyclo[5.2.2.02,6]undec-8-en-8-carboxylate

Conditions
ConditionsYield
With [bis(acetoxy)iodo]benzene at 50℃; for 1h; Diels-Alder reaction;98%
With [bis(acetoxy)iodo]benzene at 50℃; for 1h; Oxidation; Diels-Alder cycloaddition;88%
methanol
67-56-1

methanol

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

benzyl vinyl ether
935-04-6

benzyl vinyl ether

methyl (1S*,4S*,7S*)-7-(benzyloxy)-3,3-dimethoxy-2-oxobicyclo[2.2.2]oct-5-en-5-carboxylate

methyl (1S*,4S*,7S*)-7-(benzyloxy)-3,3-dimethoxy-2-oxobicyclo[2.2.2]oct-5-en-5-carboxylate

Conditions
ConditionsYield
With [bis(acetoxy)iodo]benzene at 0℃; for 1h; Product distribution; Further Variations:; Temperatures; Diels-Alder reaction;98%
With [bis(acetoxy)iodo]benzene at 50℃; for 1h; Diels-Alder reaction;98%
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

ethyl iodide
75-03-6

ethyl iodide

4-ethoxy-3-methoxybenzoic acid methyl ester
3535-24-8

4-ethoxy-3-methoxybenzoic acid methyl ester

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 100℃;98%
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 2h; Alkylation;82%
With potassium carbonate In N,N-dimethyl-formamide
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

1-iodo-propane
107-08-4

1-iodo-propane

methyl 3-methoxy-4-propoxybenzoate
3535-26-0

methyl 3-methoxy-4-propoxybenzoate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 100℃;98%
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

Dibenzyl N,N-diisopropylphosphoramidite
108549-23-1

Dibenzyl N,N-diisopropylphosphoramidite

methyl 4-((bis(benzyloxy)phosphoryl)oxy)-3-methoxybenzoate

methyl 4-((bis(benzyloxy)phosphoryl)oxy)-3-methoxybenzoate

Conditions
ConditionsYield
With 1H-tetrazole; dihydrogen peroxide In dichloromethane; water at 0 - 20℃; for 1h;98%
Stage #1: 4-hydroxy-3-methoxybenzoic acid methyl ester; Dibenzyl N,N-diisopropylphosphoramidite With 1H-tetrazole In dichloromethane; acetonitrile at 20℃; for 8h;
Stage #2: With dihydrogen peroxide In dichloromethane; acetonitrile at 20℃; for 2h;
97%
Stage #1: 4-hydroxy-3-methoxybenzoic acid methyl ester; Dibenzyl N,N-diisopropylphosphoramidite With 1H-tetrazole In dichloromethane; acetonitrile at 20℃; for 8h;
Stage #2: With dihydrogen peroxide In dichloromethane; acetonitrile at 0 - 20℃; for 2h;
97%
Stage #1: 4-hydroxy-3-methoxybenzoic acid methyl ester; Dibenzyl N,N-diisopropylphosphoramidite With 1H-tetrazole In dichloromethane; acetonitrile at 20℃; for 8h;
Stage #2: With dihydrogen peroxide In dichloromethane; acetonitrile at 0 - 20℃; for 2h;
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

1-Bromo-2-chloroethane
107-04-0

1-Bromo-2-chloroethane

4-(2-Chloro-ethoxy)-5-methoxy-benzoic acid methyl ester
214470-56-1

4-(2-Chloro-ethoxy)-5-methoxy-benzoic acid methyl ester

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 80 - 85℃; for 8h; Heating / reflux;97.8%
With potassium carbonate In N,N-dimethyl-formamide at 70℃; for 3h;97%
ethyl bromide
74-96-4

ethyl bromide

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

4-ethoxy-3-methoxybenzoic acid methyl ester
3535-24-8

4-ethoxy-3-methoxybenzoic acid methyl ester

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 70℃; for 2h;97%
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

4-bromo-2-fluorobenzyl bromide
76283-09-5

4-bromo-2-fluorobenzyl bromide

4-(4-bromo-2-fluoro-benzyloxy)-3-methoxy-benzoic acid methyl ester

4-(4-bromo-2-fluoro-benzyloxy)-3-methoxy-benzoic acid methyl ester

Conditions
ConditionsYield
Stage #1: 4-hydroxy-3-methoxybenzoic acid methyl ester With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: 4-bromo-2-fluorobenzyl bromide In N,N-dimethyl-formamide at 20℃;
96%
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

1-chloro-2-(2-methoxyethoxy)ethane
52808-36-3

1-chloro-2-(2-methoxyethoxy)ethane

3-methoxy-4-[2-(2-methoxyethoxy)ethoxy]benzoic acid methyl ester
857934-56-6

3-methoxy-4-[2-(2-methoxyethoxy)ethoxy]benzoic acid methyl ester

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 60℃; for 24h;96%
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

2-Fluoroaniline
348-54-9

2-Fluoroaniline

methyl 4-((2-fluorophenyl)amino)-3-methoxybenzoate

methyl 4-((2-fluorophenyl)amino)-3-methoxybenzoate

Conditions
ConditionsYield
With potassium phosphate; trifluoromethylsulfonic anhydride; methanesulfonato(2-dicyclohexylphosphino-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-methylamino-1,1'-biphenyl-2-yl)palladium(II) In water; toluene at 120℃; Flow reactor;96%
methanol
67-56-1

methanol

4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

methyl vinyl ketone
78-94-4

methyl vinyl ketone

C14H18O6

C14H18O6

Conditions
ConditionsYield
Stage #1: methanol; 4-hydroxy-3-methoxybenzoic acid methyl ester With iodobenzene; 3-chloro-benzenecarboperoxoic acid
Stage #2: methyl vinyl ketone In methanol at 20℃; for 0.5h; Diels-Alder Cycloaddition;
96%
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

cyclopentyl iodide
1556-18-9

cyclopentyl iodide

methyl-3-methoxy-4-cyclopentyl-oxybenzoate

methyl-3-methoxy-4-cyclopentyl-oxybenzoate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 100℃;96%
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

tert-butyl N-(2-chloroethyl)carbamate
71999-74-1

tert-butyl N-(2-chloroethyl)carbamate

methyl 4-{2-[(tert-butoxycarbonyl)amino]ethoxy}-3-methoxybenzoate
1569084-51-0

methyl 4-{2-[(tert-butoxycarbonyl)amino]ethoxy}-3-methoxybenzoate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 80℃;96%
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

cyclopropylmethyl halide

cyclopropylmethyl halide

methyl 4-(cyclopropylmethoxy)-3-methoxybenzoate
1040724-12-6

methyl 4-(cyclopropylmethoxy)-3-methoxybenzoate

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 170℃; for 1h; Microwave irradiation; Sealed tube;96%
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

1-bromomethyl-4-bromobenzene
589-15-1

1-bromomethyl-4-bromobenzene

4-(4-bromo-benzyloxy)-3-methoxy-benzoic acid methyl ester

4-(4-bromo-benzyloxy)-3-methoxy-benzoic acid methyl ester

Conditions
ConditionsYield
Stage #1: 4-hydroxy-3-methoxybenzoic acid methyl ester With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: 1-bromomethyl-4-bromobenzene In N,N-dimethyl-formamide at 20℃;
95%
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

1-chloro-3,6,9-trioxadecane
52995-76-3

1-chloro-3,6,9-trioxadecane

3-methoxy-4-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}benzoic acid methyl ester
857934-57-7

3-methoxy-4-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}benzoic acid methyl ester

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 60℃; for 24h;95%
4-hydroxy-3-methoxybenzoic acid methyl ester
3943-74-6

4-hydroxy-3-methoxybenzoic acid methyl ester

2-(trifluoromethoxy)ethyl trifluoromethanesulphonate
329710-76-1

2-(trifluoromethoxy)ethyl trifluoromethanesulphonate

methyl 3-methoxy-4-(2-(trifluoromethoxy)ethoxy)benzoate
1346498-24-5

methyl 3-methoxy-4-(2-(trifluoromethoxy)ethoxy)benzoate

Conditions
ConditionsYield
Stage #1: 4-hydroxy-3-methoxybenzoic acid methyl ester With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.666667h; Inert atmosphere;
Stage #2: 2-(trifluoromethoxy)ethyl trifluoromethanesulphonate In N,N-dimethyl-formamide; mineral oil at 0 - 40℃; for 0.666667h;
95%
Stage #1: 4-hydroxy-3-methoxybenzoic acid methyl ester With sodium hydride In N,N-dimethyl-formamide Inert atmosphere;
Stage #2: 2-(trifluoromethoxy)ethyl trifluoromethanesulphonate In N,N-dimethyl-formamide at 20 - 50℃; for 4h;

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