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Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

Spiro[3H-2,1-benzoxathiole-3,9'-[9H]xanthene], 3',6'-dichloro-, 1,1-dioxide

Cas:77545-45-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

3',6'-dichlorospiro[benzo[c][1,2]oxathiole-3,9'-xanthene] 1,1-dioxide CAS:77545-45-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chem

3',6'-dichlorospiro[benzo[c][1,2]oxathiole-3,9'-xanthene] 1,1-dioxide CAS:77545-45-0

Cas:77545-45-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Spiro[3H-2,1-benzoxathiole-3,9'-[9H]xanthene], 3',6'-dichloro-, 1,1-dioxide

Cas:77545-45-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Spiro[3H-2,1-benzoxathiole-3,9'-[9H]xanthene], 3',6'-dichloro-, 1,1-dioxide

Cas:77545-45-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Spiro[3H-2,1-benzoxathiole-3,9'-[9H]xanthene], 3',6'-dichloro-, 1,1-dioxide

Cas:77545-45-0

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals

3',6'-dichlorospiro[benzo[c][1,2]oxathiole-3,9'-xanthene] 1,1-dioxide

Cas:77545-45-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

Spiro[3H-2,1-benzoxathiole-3,9'-[9H]xanthene], 3',6'-dichloro-, 1,1-dioxide

Cas:77545-45-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

3',6'-dichlorospiro[benzo[c][1,2]oxathiole-3,9'-xanthene] 1,1-dioxide

Cas:77545-45-0

Min.Order:0

Negotiable

Type:Manufacturers

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Spiro[3H-2,1-benzoxathiole-3,9'-[9H]xanthene], 3',6'-dichloro-, 1,1-dioxide

Cas:77545-45-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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DB BIOTECH CO., LTD

best seller Application:API

3',6'-dichlorospiro[benzo[c][1,2]oxathiole-3,9'-xanthene] 1,1-dioxide

Cas:77545-45-0

Min.Order:0

Negotiable

Type:Trading Company

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Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

3',6'-dichlorospiro[benzo[c][1,2]oxathiole-3,9'-xanthene] 1,1-dioxide

Cas:77545-45-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

77545-45-0

Cas:77545-45-0

Min.Order:0

Negotiable

Type:Trading Company

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Hebei Muhuang Technology Co., Ltd

best seller Application:API

3',6'-dichlorospiro[benzo[c][1,2]oxathiole-3,9'-xanthene] 1,1-dioxide

Cas:77545-45-0

Min.Order:0

Negotiable

Type:Trading Company

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Chemsigma International Co.,Ltd.

bulk?production Application:Pharmaceutical intermediates

3',6'-dichlorospiro[benzo[c][1,2]oxathiole-3,9'-xanthene] 1,1-dioxide

Cas:77545-45-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

3',6'-dichlorospiro[benzo[c][1,2]oxathiole-3,9'-xanthene] 1,1-dioxide

Cas:77545-45-0

Min.Order:0

Negotiable

Type:Trading Company

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Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

3',6'-dichlorospiro[benzo[c][1,2]oxathiole-3,9'-xanthene] 1,1-dioxide

Cas:77545-45-0

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

HuBei Ipure Biotech CO.,ltd

HuBei ipure is a diversified product production and operation enterprise, with API, pharma intermediates, and other fine chemicals as well as R&D and pigments development and sales as one of the large enterprises, with more than 130 acres of

Spiro[3H-2,1-benzoxathiole-3,9'-[9H]xanthene], 3',6'-dichloro-, 1,1-dioxide

Cas:77545-45-0

Min.Order:1 Gram

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Nanjing Raymon Biotech Co., Ltd.

Spiro[3H-2,1-benzoxathiole-3,9'-[9H]xanthene], 3',6'-dichloro-, 1,1-dioxide Storage:Store in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical research/Pharmaceutical intermediates Transportation:By Sea,by Air,

Spiro[3H-2,1-benzoxathiole-3,9'-[9H]xanthene], 3',6'-dichloro-, 1,1-dioxide

Cas:77545-45-0

Min.Order:0

Negotiable

Type:Trading Company

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Sino-Biochemical Laboratory Co.,Ltd

High quality ,special structure, regular with stock , custom synthese ,quotation with 24hrsAppearance:Good Storage:G to KG to 100KG Application:With high quality for lab research or production in pharm or special material area . With stock or custom

spiro[3H-2,1-benzoxathiole-3,9'-[9H]xanthene],3',6'-dichloro,1,1-dioxide

Cas:77545-45-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Ruishun Trade Co.,Ltd

Supply top quality products with a reasonable price Application:api

77545-45-0

Cas:77545-45-0

Min.Order:0

Negotiable

Type:Trading Company

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pharmatiecoltld

Spiro[3H-2,1-benzoxathiole-3,9'-[9H]xanthene], 3',6'-dichloro-, 1,1-dioxide for sale available now in good price Appearance:WHITE Storage:Spiro[3H-2,1-benzoxathiole-3,9'-[9H]xanthene], 3',6'-dichloro-, 1,1-dioxide Package:allumium foi

Spiro[3H-2,1-benzoxathiole-3,9'-[9H]xanthene], 3',6'-dichloro-, 1,1-dioxide

Cas:77545-45-0

Min.Order:100 Gram

FOB Price: $250.0

Type:Manufacturers

inquiry

Synthetic route

sulfonefluorescein
4424-03-7

sulfonefluorescein

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

Conditions
ConditionsYield
With trichlorophosphate at 105℃; for 18h;56%
With trichlorophosphate at 90℃; for 2h;53.4 g
With trichlorophosphate at 90℃; for 2h;53.4 g
sulfonfluorescein

sulfonfluorescein

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

Conditions
ConditionsYield
With phosphorus pentachloride at 125 - 130℃;
benzoyl chloride
98-88-4

benzoyl chloride

sulfonfluorescein

sulfonfluorescein

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

Conditions
ConditionsYield
at 200℃;
o-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzenesulphonic acid

o-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzenesulphonic acid

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

Conditions
ConditionsYield
With thionyl chloride In N,N-dimethyl-formamide at 100℃; for 1h; Inert atmosphere;
With thionyl chloride
2-sulfobenzoic acid cyclic anhydride
81-08-3

2-sulfobenzoic acid cyclic anhydride

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 0.5 h / 140 °C
2: trichlorophosphate / 2 h / 90 °C
View Scheme
recorcinol
108-46-3

recorcinol

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 0.5 h / 140 °C
2: trichlorophosphate / 2 h / 90 °C
View Scheme
saccharin
81-07-2

saccharin

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sulfuric acid / sulfolane / 20 h / 120 - 140 °C
2: trichlorophosphate / 18 h / 105 °C
View Scheme
3-amino-2,4,6-trimethylbenzenesulfonic acid sodium salt

3-amino-2,4,6-trimethylbenzenesulfonic acid sodium salt

C10H15NO2

C10H15NO2

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

C39H37N2O8S2(1-)*Na(1+)

C39H37N2O8S2(1-)*Na(1+)

Conditions
ConditionsYield
Stage #1: 3-amino-2,4,6-trimethylbenzenesulfonic acid sodium salt; 3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide With 1,8-diazabicyclo[5.4.0]undec-7-ene; magnesium chloride In ethylene glycol at 120℃; for 2h;
Stage #2: C10H15NO2 In ethylene glycol at 150℃; for 5h;
95%
C12H18N2O

C12H18N2O

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

C43H44N4O6S

C43H44N4O6S

Conditions
ConditionsYield
With zinc(II) chloride In sulfolane at 180℃; for 6h; Solvent; Temperature;94%
C11H16NO3S(1-)*Na(1+)

C11H16NO3S(1-)*Na(1+)

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

2,6-dimethylaniline
87-62-7

2,6-dimethylaniline

C38H35N2O7S2(1-)*Na(1+)

C38H35N2O7S2(1-)*Na(1+)

Conditions
ConditionsYield
Stage #1: C11H16NO3S(1-)*Na(1+); 3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide With 1,8-diazabicyclo[5.4.0]undec-7-ene; magnesium triflate In ethylene glycol at 120℃; for 2h;
Stage #2: 2,6-dimethylaniline In ethylene glycol at 150℃; for 5h;
94%
3-amino-2,4,6-trimethylbenzenesulfonic acid sodium salt

3-amino-2,4,6-trimethylbenzenesulfonic acid sodium salt

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

2-(2-aminophenyl)propionitrile
88975-17-1

2-(2-aminophenyl)propionitrile

C37H30N3O7S2(1-)*Na(1+)

C37H30N3O7S2(1-)*Na(1+)

Conditions
ConditionsYield
Stage #1: 3-amino-2,4,6-trimethylbenzenesulfonic acid sodium salt; 3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide With 1,8-diazabicyclo[5.4.0]undec-7-ene; magnesium chloride In ethylene glycol at 120℃; for 2h;
Stage #2: 2-(2-aminophenyl)propionitrile In ethylene glycol at 150℃; for 5h;
94%
C10H14NO3S(1-)*Na(1+)
1047719-94-7

C10H14NO3S(1-)*Na(1+)

C10H12N2

C10H12N2

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

C39H36N3O7S2(1-)*Na(1+)

C39H36N3O7S2(1-)*Na(1+)

Conditions
ConditionsYield
Stage #1: C10H14NO3S(1-)*Na(1+); 3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide With 1,8-diazabicyclo[5.4.0]undec-7-ene; magnesium chloride In ethylene glycol at 120℃; for 2h;
Stage #2: C10H12N2 In ethylene glycol at 150℃; for 5h;
93%
C10H14NO5S(1-)*Na(1+)

C10H14NO5S(1-)*Na(1+)

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

2,4,6-trimethylaniline
88-05-1

2,4,6-trimethylaniline

C39H37N2O9S2(1-)*Na(1+)

C39H37N2O9S2(1-)*Na(1+)

Conditions
ConditionsYield
Stage #1: C10H14NO5S(1-)*Na(1+); 3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide With 1,8-diazabicyclo[5.4.0]undec-7-ene; magnesium chloride In ethylene glycol at 120℃; for 2h;
Stage #2: 2,4,6-trimethylaniline In ethylene glycol at 150℃; for 8h;
92%
C10H14NO5S(1-)*Na(1+)

C10H14NO5S(1-)*Na(1+)

C13H21NO3

C13H21NO3

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

C42H43N2O12S2(1-)*Na(1+)

C42H43N2O12S2(1-)*Na(1+)

Conditions
ConditionsYield
Stage #1: C10H14NO5S(1-)*Na(1+); 3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide With 1,8-diazabicyclo[5.4.0]undec-7-ene; magnesium chloride In ethylene glycol at 120℃; for 2h;
Stage #2: C13H21NO3 In ethylene glycol at 150℃; for 5h;
92%
3-amino-2,4,6-trimethylbenzenesulfonic acid sodium salt

3-amino-2,4,6-trimethylbenzenesulfonic acid sodium salt

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

2,4,6-trimethylaniline
88-05-1

2,4,6-trimethylaniline

C37H33N2O7S2(1-)*Na(1+)

C37H33N2O7S2(1-)*Na(1+)

Conditions
ConditionsYield
Stage #1: 3-amino-2,4,6-trimethylbenzenesulfonic acid sodium salt; 3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide With 1,8-diazabicyclo[5.4.0]undec-7-ene; magnesium chloride In ethylene glycol at 120℃; for 2h;
Stage #2: 2,4,6-trimethylaniline In ethylene glycol at 150℃; for 5h;
92%
3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

3,5-dimethylsulphanilic acid, sodium salt

3,5-dimethylsulphanilic acid, sodium salt

C36H31N2O7S2(1-)*Na(1+)

C36H31N2O7S2(1-)*Na(1+)

Conditions
ConditionsYield
Stage #1: 3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide; 3,5-dimethylsulphanilic acid, sodium salt With magnesium(II) chloride hexahydrate; 1,8-diazabicyclo[5.4.0]undec-7-ene In ethylene glycol at 120℃;
Stage #2: 3,5-dimethylsulphanilic acid, sodium salt In ethylene glycol at 150℃; for 8h;
92%
C9H12NO3S(1-)*Na(1+)

C9H12NO3S(1-)*Na(1+)

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

C37H32N2O10S3(2-)*2Na(1+)

C37H32N2O10S3(2-)*2Na(1+)

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene; magnesium chloride In ethylene glycol at 150℃; for 10h;91%
4-trifluoromethylphenylamine
455-14-1

4-trifluoromethylphenylamine

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

3,5-dimethylsulphanilic acid, sodium salt

3,5-dimethylsulphanilic acid, sodium salt

C34H24F3N2O7S2(1-)*Na(1+)

C34H24F3N2O7S2(1-)*Na(1+)

Conditions
ConditionsYield
Stage #1: 3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide; 3,5-dimethylsulphanilic acid, sodium salt With magnesium oxide; 1,8-diazabicyclo[5.4.0]undec-7-ene In ethylene glycol at 120℃; for 2h;
Stage #2: 4-trifluoromethylphenylamine In ethylene glycol at 150℃; for 8h;
91%
p-toluidine
106-49-0

p-toluidine

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

C33H26N2O4S

C33H26N2O4S

Conditions
ConditionsYield
In ethylene glycol at 120℃; for 18h;90.96%
In 1-methyl-pyrrolidin-2-one at 120℃; for 6h;
C14H20N2O

C14H20N2O

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

C47H48N4O6S

C47H48N4O6S

Conditions
ConditionsYield
With zinc(II) chloride In sulfolane at 150℃; for 8h;90%
3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

2,4,6-trimethylaniline
88-05-1

2,4,6-trimethylaniline

C37H34N2O4S

C37H34N2O4S

Conditions
ConditionsYield
With zinc(II) chloride In sulfolane at 200℃; for 3h;90%
In 1-methyl-pyrrolidin-2-one at 150℃; for 4h;39%
Stage #1: 3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide; 2,4,6-trimethylaniline With zinc(II) chloride In sulfolane at 200℃; for 3h;
Stage #2: With hydrogenchloride In water; acetonitrile at 45℃; for 0.5h;
80.4 g
With zinc(II) chloride In sulfolane at 200℃; for 3h;80 g
With zinc(II) chloride In sulfolane at 200℃; for 3h;80 g
C10H14NO4S(1-)*Na(1+)

C10H14NO4S(1-)*Na(1+)

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

C39H36N2O12S3(2-)*2Na(1+)

C39H36N2O12S3(2-)*2Na(1+)

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene; magnesium chloride In ethylene glycol at 150℃; for 10h;90%
3-amino-2,4,6-trimethylbenzenesulfonic acid sodium salt

3-amino-2,4,6-trimethylbenzenesulfonic acid sodium salt

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

C37H32N2O10S3(2-)*2Na(1+)

C37H32N2O10S3(2-)*2Na(1+)

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene; magnesium chloride In ethylene glycol at 150℃; for 10h;90%
3-amino-2,4,6-trimethylbenzenesulfonic acid sodium salt

3-amino-2,4,6-trimethylbenzenesulfonic acid sodium salt

2-methyl-6-pentafluoroethylaniline
273735-58-3

2-methyl-6-pentafluoroethylaniline

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

C37H28F5N2O7S2(1-)*Na(1+)

C37H28F5N2O7S2(1-)*Na(1+)

Conditions
ConditionsYield
Stage #1: 3-amino-2,4,6-trimethylbenzenesulfonic acid sodium salt; 3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide With 1,8-diazabicyclo[5.4.0]undec-7-ene; magnesium chloride In ethylene glycol at 120℃; for 2h;
Stage #2: 2-methyl-6-pentafluoroethylaniline In ethylene glycol at 180℃; for 18h;
90%
3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

3,5-dimethylsulphanilic acid, sodium salt

3,5-dimethylsulphanilic acid, sodium salt

C35H28N2O10S3(2-)*2Na(1+)

C35H28N2O10S3(2-)*2Na(1+)

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene; magnesium chloride In ethylene glycol at 150℃; for 10h;90%
3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

diethylamine
109-89-7

diethylamine

C31H40N3O3S(1+)

C31H40N3O3S(1+)

Conditions
ConditionsYield
In 1-methyl-pyrrolidin-2-one at 120℃; for 5h;90%
3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

o-toluidine
95-53-4

o-toluidine

C33H26N2O4S

C33H26N2O4S

Conditions
ConditionsYield
With 1-methyl-2-pyridone at 120℃; for 8h;89%
In 1-methyl-pyrrolidin-2-one at 150℃; for 4h;45%
C10H14NO4S(1-)*Na(1+)

C10H14NO4S(1-)*Na(1+)

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

C39H36N2O12S3(2-)*2Na(1+)

C39H36N2O12S3(2-)*2Na(1+)

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene; magnesium bromide In ethylene glycol at 150℃; for 10h;89%
2,6-diisopropylbenzenamine
24544-04-5

2,6-diisopropylbenzenamine

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

C43H46N2O4S

C43H46N2O4S

Conditions
ConditionsYield
With zinc(II) chloride In sulfolane at 200℃; for 4h;88%
With magnesium chloride In sulfolane at 80 - 125℃; for 53h;70.8%
2,6-diethyl-4-methylaniline
24544-08-9

2,6-diethyl-4-methylaniline

C11H16NO3S(1-)*Na(1+)

C11H16NO3S(1-)*Na(1+)

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

C41H41N2O7S2(1-)*Na(1+)

C41H41N2O7S2(1-)*Na(1+)

Conditions
ConditionsYield
Stage #1: C11H16NO3S(1-)*Na(1+); 3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide With 1,8-diazabicyclo[5.4.0]undec-7-ene; magnesium bromide In ethylene glycol at 120℃; for 2h;
Stage #2: 2,6-diethyl-4-methylaniline In ethylene glycol at 180℃; for 18h; Reagent/catalyst;
88%
3-Amino-2,4,6-trimethyl-phenol
114960-27-9

3-Amino-2,4,6-trimethyl-phenol

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

C37H34N2O6S

C37H34N2O6S

Conditions
ConditionsYield
With sulfolane; zinc(II) chloride at 200℃; for 6h;87%
C10H14NO5S(1-)*Na(1+)

C10H14NO5S(1-)*Na(1+)

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

C39H36N2O14S3(2-)*2Na(1+)

C39H36N2O14S3(2-)*2Na(1+)

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene; magnesium bromide In ethylene glycol at 150℃; for 14h;87%
C11H16NO3S(1-)*Na(1+)

C11H16NO3S(1-)*Na(1+)

C10H14NO4S(1-)*Na(1+)

C10H14NO4S(1-)*Na(1+)

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

C40H38N2O11S3(2-)*2Na(1+)

C40H38N2O11S3(2-)*2Na(1+)

Conditions
ConditionsYield
Stage #1: C11H16NO3S(1-)*Na(1+); 3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide With 1,8-diazabicyclo[5.4.0]undec-7-ene; magnesium bromide In ethylene glycol at 120℃; for 3h;
Stage #2: C10H14NO4S(1-)*Na(1+) In ethylene glycol at 180℃; for 18h;
86%
3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

2,6-dimethylaniline
87-62-7

2,6-dimethylaniline

C35H30N2O4S

C35H30N2O4S

Conditions
ConditionsYield
With 1-methyl-2-pyridone at 150℃; for 8h; Darkness;85%
With 1-methyl-2-pyridone In 1-methyl-pyrrolidin-2-one at 150℃; for 8h;85%
With zinc(II) chloride In sulfolane at 200℃; for 4h;65.6%
2,6-diethyl-4-methylaniline
24544-08-9

2,6-diethyl-4-methylaniline

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

3,5-diisopropyl sulfanilic acid sodium salt

3,5-diisopropyl sulfanilic acid sodium salt

C42H43N2O7S2(1-)*Na(1+)

C42H43N2O7S2(1-)*Na(1+)

Conditions
ConditionsYield
Stage #1: 3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide; 3,5-diisopropyl sulfanilic acid sodium salt With 1,8-diazabicyclo[5.4.0]undec-7-ene; magnesium bromide In ethylene glycol at 120℃; for 2h;
Stage #2: 2,6-diethyl-4-methylaniline In ethylene glycol at 180℃; for 18h;
85%
3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

diethylamine
109-89-7

diethylamine

C27H30N2O4S

C27H30N2O4S

Conditions
ConditionsYield
In isopropyl alcohol at 80℃; for 8h;84%
In isopropyl alcohol at 80℃; for 8h;84%
In isopropyl alcohol at 80℃; for 8h;84%
3-amino-2,4,6-trimethylbenzenesulfonic acid sodium salt

3-amino-2,4,6-trimethylbenzenesulfonic acid sodium salt

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide
77545-45-0

3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide

3,5-diisopropyl sulfanilic acid sodium salt

3,5-diisopropyl sulfanilic acid sodium salt

C40H38N2O10S3(2-)*2Na(1+)

C40H38N2O10S3(2-)*2Na(1+)

Conditions
ConditionsYield
Stage #1: 3’,6’-dichlorospiro[3H-2,1-benzoxathiol-3,9’-[9H]xanthene]-1,1-dioxide; 3,5-diisopropyl sulfanilic acid sodium salt With 1,8-diazabicyclo[5.4.0]undec-7-ene; magnesium chloride In ethylene glycol at 120℃; for 3h;
Stage #2: 3-amino-2,4,6-trimethylbenzenesulfonic acid sodium salt In ethylene glycol at 180℃; for 18h;
84%
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