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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

(S)-(-)-5-Hydroxymethyl-2(5H)-furanone Manufacturer/High quality/Best price/In stock

Cas:78508-96-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

(S)-(-)-5-Hydroxymethyl-2(5H)-furanone

Cas:78508-96-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so

C5H6O3 78508-96-0 (S)-(-)HYDROXYMETHYL-3(2H)-FURANONE

Cas:78508-96-0

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

(S)-(-)HYDROXYMETHYL-3(2H)-FURANONE

Cas:78508-96-0

Min.Order:1 Kilogram

FOB Price: $2.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 78508-96-0 with best quality

Cas:78508-96-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2(5H)-Furanone,5-(hydroxymethyl)-, (5S)- 78508-96-0

Cas:78508-96-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2(5H)-Furanone,5-(hydroxymethyl)-, (5S)-

Cas:78508-96-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

(S)-(-)HYDROXYMETHYL-3(2H)-FURANONE

Cas:78508-96-0

Min.Order:1 Kilogram

FOB Price: $10.0 / 100.0

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2(5H)-Furanone,5-(hydroxymethyl)-, (5S)-

Cas:78508-96-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

(S)-(-)-5-Hydroxymethyl-2(5H)-Furanone

Cas:78508-96-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply (S)-(-)-5-Hydroxymethyl-2(5H)-furanone

Cas:78508-96-0

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2(5H)-Furanone,5-(hydroxymethyl)-, (5S)-

Cas:78508-96-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

(S)-( )-5-Hydroxymethyl-2(5H)-furanone

Cas:78508-96-0

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

(S)-( )-5-Hydroxymethyl-2(5H)-furanone

Cas:78508-96-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

(S)-( )-5-Hydroxymethyl-2(5H)-furanone

Cas:78508-96-0

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

(S)-(-)-5-(Hydroxymethyl)-2(5H)-furanone

Cas:78508-96-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

(S)-( )-5-Hydroxymethyl-2(5H)-furanone

Cas:78508-96-0

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

(S)-(-)-5-Hydroxymethyl-2(5H)furanone

Cas:78508-96-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates

2(5H)-Furanone,5-(hydroxymethyl)-, (5S)-

Cas:78508-96-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Henan Allgreen Chemical Co.,Ltd

high qualityAppearance:white crystalline powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

2-(4-METHOXYPHENYL)-2-PHENYLACETIC ACID

Cas:78508-96-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

(S)-(-)-5-Hydroxymethyl-2(5H)-Furanone

Cas:78508-96-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

(S)-(-)HYDROXYMETHYL-3(2H)-FURANONE

Cas:78508-96-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

2(5H)-Furanone,5-(hydroxymethyl)-, (5S)-

Cas:78508-96-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

(S)-(?)-5-Hydroxymethyl-2(5H)-furanone Application:(S)-( )-5-Hydroxymethyl-2(5H)-furanone

(S)-( )-5-Hydroxymethyl-2(5H)-furanone

Cas:78508-96-0

Min.Order:0

Negotiable

Type:Other

inquiry

DB BIOTECH CO., LTD

best seller Application:API

(S)-(-)HYDROXYMETHYL-3(2H)-FURANONE

Cas:78508-96-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:clear light yellow liquid Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use

(S)-(-)-5-Hydroxymethyl-2(5H)-furanone

Cas:78508-96-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

(S)-(-)-5-Hydroxymethyl-2(5H)-furanone cas 78508-96-0Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

(S)-(-)-5-Hydroxymethyl-2(5H)-furanone cas 78508-96-0

Cas:78508-96-0

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

(S)-(-)HYDROXYMETHYL-3(2H)-FURANONE

Cas:78508-96-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

78508-96-0

Cas:78508-96-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hunan Longxianng Runhui Trading Co.,Ltd

(S)-(?)-5-Hydroxymethyl-2(5H)-furanoneAppearance:white crystalline powder Storage:Shading, sealed, dry place. Package:aluminous bag Application:API Transportation:By express (Door to door) such as FEDEX, DHL, EMS for small amount. By air(airport to a

(S)-( )-5-Hydroxymethyl-2(5H)-furanone

Cas:78508-96-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

methyl (2Z)-3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]acrylate
81703-94-8

methyl (2Z)-3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]acrylate

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
With sulfuric acid In methanol at 23℃; for 2h;97%
With camphor-10-sulfonic acid In methanol at 20℃;95%
With sulfuric acid In methanol at 20℃; for 2h;93%
With hydrogenchloride In water; acetonitrile for 2.75h; Product distribution; Further Variations:; Reagents;84%
With camphor-10-sulfonic acid at 25℃; for 3h;
(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
With sulfuric acid In methanol for 0.5h; Ambient temperature;95%
With sulfuric acid In methanol
ethyl (Z)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)acrylate
91926-90-8

ethyl (Z)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)acrylate

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
With hydrogenchloride90%
With hydrogenchloride In ethanol for 2h; Ambient temperature;81%
With sulfuric acid
2,3-dideoxy-5-O-(triphenylmethyl)-D-glycero-pent-2-enono-1,4-lactone
76236-32-3

2,3-dideoxy-5-O-(triphenylmethyl)-D-glycero-pent-2-enono-1,4-lactone

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
With hydrogenchloride In methanol for 2h; Ambient temperature;90%
With hydrogenchloride; methanol
methyl (S)-4,5-dihydroxy-4,5-O-isopropylidene-2-pentenoate
66601-82-9

methyl (S)-4,5-dihydroxy-4,5-O-isopropylidene-2-pentenoate

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
With sulfuric acid In methanol at 25℃; for 1h;90%
With sulfuric acid; water In methanol at 20℃; for 2h; Cyclization;85%
levoglucosenone
37112-31-5

levoglucosenone

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
With dihydrogen peroxide In water at 50℃; for 10h; Baeyer-Villiger Ketone Oxidation; Inert atmosphere; Cooling with ice;84%
Stage #1: levoglucosenone With Candida antarctica B lipase; dihydrogen peroxide In ethyl acetate at 40℃; for 8h; Baeyer-Villiger Ketone Oxidation; Green chemistry; Enzymatic reaction;
Stage #2: In 1,4-dioxane at 20℃; for 8h; Catalytic behavior; Reagent/catalyst; Temperature; Concentration; Green chemistry; regioselective reaction;
83%
With dihydrogen peroxide In water at 0 - 50℃; for 1h; Baeyer-Villiger Ketone Oxidation;76%
(5S)-5-(tert-butyldimethylsilanyloxymethyl)-5H-furan-2-one
105122-15-4

(5S)-5-(tert-butyldimethylsilanyloxymethyl)-5H-furan-2-one

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
With water; acetic acid In tetrahydrofuran at 24℃; for 22h;82%
With acetic acid In tetrahydrofuran; water at 24℃; for 22h;82%
levoglucosenone
37112-31-5

levoglucosenone

A

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

B

(-)-(S)-5-formyloxymethyloxol-3-en-2one
85846-84-0

(-)-(S)-5-formyloxymethyloxol-3-en-2one

Conditions
ConditionsYield
With dihydrogen peroxide In water at 50℃; for 10h; Baeyer-Villiger Ketone Oxidation; Inert atmosphere; Cooling with ice; Large scale;A 71%
B n/a
With peracetic acid; dimethylsulfide; acetic acid 1.) RT, 2 d, 2.) 1 h; Multistep reaction. Title compound not separated from byproducts;
With Candida antarctica B lipase; dihydrogen peroxide In ethyl acetate at 40℃; for 8h; Catalytic behavior; Reagent/catalyst; Temperature; Concentration; Baeyer-Villiger Ketone Oxidation; Green chemistry; Enzymatic reaction; regioselective reaction;
D-Ribono-1,4-lactone
5336-08-3

D-Ribono-1,4-lactone

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
With methyltrioxorhenium(VII) at 170 - 180℃; for 15h; Sealed tube; Inert atmosphere;70%
Multi-step reaction with 2 steps
1: 1.) THF, 12 h, reflux, 2.) 7 d
2: 68 percent / 220 °C / 40 Torr
View Scheme
Multi-step reaction with 2 steps
1: tetrahydrofuran / 12 h / Heating
2: 68 percent / 220 °C / 40 Torr
View Scheme
With methyltrioxorhenium(VII) at 155℃; for 2h; Inert atmosphere;23.5 mg
2,3-O-(ethoxymethylene)-D-ribonic acid γ-lactone
78508-93-7

2,3-O-(ethoxymethylene)-D-ribonic acid γ-lactone

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
at 220℃; under 40 Torr;68%
(+)-2,3-O-ethoxymethylene-D-ribonolactone
78508-93-7

(+)-2,3-O-ethoxymethylene-D-ribonolactone

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
at 220℃; under 40 Torr;68%
2-deoxy-3,5-di-O-(p-chlorobenzoyl)-γ-D-ribonolactone

2-deoxy-3,5-di-O-(p-chlorobenzoyl)-γ-D-ribonolactone

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
With N-fluorobis(benzenesulfon)imide; lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 1h;65%
methyl (S)-4,5-dihydroxy-4,5-O-isopropylidene-2-pentenoate
66601-82-9

methyl (S)-4,5-dihydroxy-4,5-O-isopropylidene-2-pentenoate

A

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

B

ethyl (E)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)acrylate
64520-58-7

ethyl (E)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)acrylate

Conditions
ConditionsYield
With sulfuric acid In methanol for 0.5h; Ambient temperature;A 63%
B n/a
(S)-tert-butyl trans-4,5-dihydroxylpent-2-enoate

(S)-tert-butyl trans-4,5-dihydroxylpent-2-enoate

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
With phenanthrene In dichloromethane at 25 - 30℃; UV-irradiation;61%
3-<(4'S)-2',2'-dimethyl-1',3'-dioxolan-4'-yl>prop-2-enoic acid ethyl ester
36326-38-2

3-<(4'S)-2',2'-dimethyl-1',3'-dioxolan-4'-yl>prop-2-enoic acid ethyl ester

A

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

B

methyl (2E)-3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]acrylate
81703-93-7

methyl (2E)-3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]acrylate

Conditions
ConditionsYield
With sulfuric acid In methanol for 0.5h; Ambient temperature;A 60%
B n/a
(S)-tert-butyl trans-4,5-dihydroxylpent-2-enoate

(S)-tert-butyl trans-4,5-dihydroxylpent-2-enoate

A

tert-butyl 5-hydroxy-4-oxopentanoate
1239346-69-0

tert-butyl 5-hydroxy-4-oxopentanoate

B

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
With adenosine In dichloromethane at 25 - 30℃; UV-irradiation;A 51%
B n/a
levoglucosenone
37112-31-5

levoglucosenone

A

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

B

2-deoxy-3-O-methyl-D-erythro-pentono-1,4-lactone
82540-80-5

2-deoxy-3-O-methyl-D-erythro-pentono-1,4-lactone

Conditions
ConditionsYield
With dihydrogen peroxide; sodium hydroxide In methanol at 18℃; for 408h;A 13%
B 4%
(-)-(S)-5-acetyloxymethyl-2(5H)-furanone
85846-83-9

(-)-(S)-5-acetyloxymethyl-2(5H)-furanone

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
With hydrogenchloride In methanol at 5℃; for 18h; Yield given;
tert-butyl 6-O-acetyl-3,4-dideoxy-α-D-glycero-hex-3-enopyranosid-2-ulose
81668-95-3

tert-butyl 6-O-acetyl-3,4-dideoxy-α-D-glycero-hex-3-enopyranosid-2-ulose

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
With peracetic acid for 12h;
2-Bromo-2-deoxy-D-arabinono-γ-lactone
78138-89-3

2-Bromo-2-deoxy-D-arabinono-γ-lactone

A

(5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran
32780-06-6

(5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran

B

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In ethanol at 20℃; under 760 Torr;
(3R/S,4S)-5-Hydroxy-4-phenylsulfinyl-4-pentanolide
105866-01-1, 105866-02-2, 115731-00-5

(3R/S,4S)-5-Hydroxy-4-phenylsulfinyl-4-pentanolide

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
With calcium carbonate In toluene for 3h; Heating; Yield given;
orthoformic acid triethyl ester
122-51-0

orthoformic acid triethyl ester

D-Ribono-1,4-lactone
5336-08-3

D-Ribono-1,4-lactone

A

protoanemonin
108-28-1

protoanemonin

B

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
1.) THF, reflux; 2.) 220 deg C, 18 Hgmm; Multistep reaction;
D-Ribono-1,4-lactone
5336-08-3

D-Ribono-1,4-lactone

A

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

B

(S)-(-)-γ-bromometil-α,β-butenolide
85694-09-3

(S)-(-)-γ-bromometil-α,β-butenolide

Conditions
ConditionsYield
Yield given. Multistep reaction;
1-(2-deoxy-2-iodo-β-D-ribofuranosyl)uracil
4753-03-1

1-(2-deoxy-2-iodo-β-D-ribofuranosyl)uracil

A

2,2'-Anhydrouridine
3736-77-4

2,2'-Anhydrouridine

B

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

C

3'-keto-2'-deoxyuridine

3'-keto-2'-deoxyuridine

D

1-((2R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione

1-((2R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione

E

2'β-iodo-2'-deoxyuridine

2'β-iodo-2'-deoxyuridine

F

2-deoxy-D-ribonolactone
34371-14-7

2-deoxy-D-ribonolactone

Conditions
ConditionsYield
In water-d2 for 4h; Product distribution; Mechanism; Irradiation; var. solvents, in the presence of O2, also <1'-D>-2'α-iodo-2'-deoxyuridine, other deoxyoligonucleotides;A 2.0 % Spectr.
B 2.0 % Spectr.
C 1.0 % Spectr.
D 4.0 % Spectr.
E 13 % Spectr.
F 1.0 % Spectr.
5-({[tert-butyl(dimethyl)silyl]oxy}methyl)-5H-furan-2-one
116561-10-5

5-({[tert-butyl(dimethyl)silyl]oxy}methyl)-5H-furan-2-one

A

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

B

(R)-(+)-5-(hydroxymethyl)furan-2(5H)-one
112837-17-9

(R)-(+)-5-(hydroxymethyl)furan-2(5H)-one

Conditions
ConditionsYield
With pyridine hydrogenfluoride In tetrahydrofuran at 0℃; for 16h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
tert-butyl (4R)-4,5-O-isopropylidene-3,4,5-trihydroxypentanoate
106183-54-4, 106183-55-5

tert-butyl (4R)-4,5-O-isopropylidene-3,4,5-trihydroxypentanoate

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 82 percent / CH3COOH / tetrahydrofuran; H2O / 22 h / 24 °C
View Scheme
Multi-step reaction with 3 steps
1: 50 percent aq. CF3COOH / 2 h / 90 - 95 °C
2: 1.)t-BuMe2SiCl; 2.) SOCl2, pyridine / 1.) CH2Cl2, 20 deg C., 16h; 2.) CH2Cl2, 24 deg C, 22h
3: 82 percent / H2O, AcOH / tetrahydrofuran / 22 h / 24 °C
View Scheme
(2E)-3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]prop-2-en-1-ol
79060-23-4

(2E)-3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]prop-2-en-1-ol

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 99 percent / Et3N / CH2Cl2 / 1 h / 20 °C
2: 84 percent / HCl / H2O; acetonitrile / 2.75 h
View Scheme
tert-butyl 2,4,6-tri-O-acetyl-3-deoxy-α-D-erythro-hex-2-enopyranoside
79698-71-8

tert-butyl 2,4,6-tri-O-acetyl-3-deoxy-α-D-erythro-hex-2-enopyranoside

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: K2CO3 / methanol / 1 h
2: pyridine, dimethylaminopyridine / CH2Cl2 / 1 h
3: 40percent aq. AcOOH / 12 h
View Scheme
tert-butyl 3,4-dideoxy-α-D-glycero-hex-3-enopyranosid-2-ulose
119794-56-8

tert-butyl 3,4-dideoxy-α-D-glycero-hex-3-enopyranosid-2-ulose

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: pyridine, dimethylaminopyridine / CH2Cl2 / 1 h
2: 40percent aq. AcOOH / 12 h
View Scheme
2,3,4,6-tetra-O-acetyl-1,5-anhydro-D-arabinohex-1-enopyranose
3366-47-0

2,3,4,6-tetra-O-acetyl-1,5-anhydro-D-arabinohex-1-enopyranose

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 87 percent / BF3*Et2O / CH2Cl2 / 72 h
2: K2CO3 / methanol / 1 h
3: pyridine, dimethylaminopyridine / CH2Cl2 / 1 h
4: 40percent aq. AcOOH / 12 h
View Scheme
(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

(5S)-5-(tert-butyldimethylsilanyloxymethyl)-5H-furan-2-one
105122-15-4

(5S)-5-(tert-butyldimethylsilanyloxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
With 1H-imidazole In dichloromethane at 0 - 20℃; for 1h;100%
With 1H-imidazole In dichloromethane at 0 - 23℃; for 1h;99%
With 1H-imidazole In dichloromethane at 20℃; for 3h;98%
(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

tetradecanoyl chloride
112-64-1

tetradecanoyl chloride

5-O-tetradecanoyl-2,3-didehydro-2,3-dideoxy-D-glycero-pentono-1,4-lactone
138433-97-3

5-O-tetradecanoyl-2,3-didehydro-2,3-dideoxy-D-glycero-pentono-1,4-lactone

Conditions
ConditionsYield
With pyridine; dmap In dichloromethane for 24h; Ambient temperature;97%
(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

tert-butylchlorodiphenylsilane
58479-61-1

tert-butylchlorodiphenylsilane

(5S)-5-(tert-butyldiphenylsiloxymethyl)-2(5H)-furanone
99315-76-1

(5S)-5-(tert-butyldiphenylsiloxymethyl)-2(5H)-furanone

Conditions
ConditionsYield
With 1H-imidazole In dichloromethane at 0℃; for 0.75h;97%
With ammonium nitrate In N,N-dimethyl-formamide at 0 - 25℃; for 12.5h;95%
With dmap94%
(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

(+/-)-3-tert-butyldimethylsilyloxy-1-cyclopentane-1-carboxylic acid
101244-99-9

(+/-)-3-tert-butyldimethylsilyloxy-1-cyclopentane-1-carboxylic acid

(-)-R-4-(3-tert-butyldimethylsilyloxycyclopent-1-ene-1-carbonyloxymethyl)but-2-en-4-olide
101244-80-8, 101244-81-9

(-)-R-4-(3-tert-butyldimethylsilyloxycyclopent-1-ene-1-carbonyloxymethyl)but-2-en-4-olide

Conditions
ConditionsYield
With dicyclohexyl-carbodiimide In dichloromethane96%
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0℃; for 2h;96%
(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

(5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran
32780-06-6

(5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In ethanol for 4h; Ambient temperature;96%
With palladium 10% on activated carbon; hydrogen In ethyl acetate at 20℃;90%
With palladium 10% on activated carbon; hydrogen In ethyl acetate at 20℃;86%
3,4-dihydro-2H-pyran
110-87-2

3,4-dihydro-2H-pyran

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

(4S)-4-hydroxy-5-tetrahydropyranyloxy-2-pentenoic acid γ-lactone
128387-70-2

(4S)-4-hydroxy-5-tetrahydropyranyloxy-2-pentenoic acid γ-lactone

Conditions
ConditionsYield
With camphor-10-sulfonic acid In tetrahydrofuran at 10℃; for 15h;95%
With camphor-10-sulfonic acid93%
With toluene-4-sulfonic acid In dichloromethane at 23℃; for 8h;78%
With toluene-4-sulfonic acid In dichloromethane at 20℃; for 8h;78%
(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

pivaloyl chloride
3282-30-2

pivaloyl chloride

(-)-(S)-5-pivaloyloxymethyl-2(5H)-furanone
139230-94-7

(-)-(S)-5-pivaloyloxymethyl-2(5H)-furanone

Conditions
ConditionsYield
With pyridine In dichloromethane at 0℃; for 24h; Esterification;95%
With pyridine; dmap In dichloromethane for 29h; Ambient temperature;89%
With pyridine In dichloromethane at 23℃; for 12h;81%
With pyridine In dichloromethane at 0 - 20℃;81%
(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

cyclopenta-1,3-diene
542-92-7

cyclopenta-1,3-diene

(2R,5S,6S)-5-Hydroxymethyl-4-oxa-tricyclo[5.2.1.02,6]dec-8-en-3-one

(2R,5S,6S)-5-Hydroxymethyl-4-oxa-tricyclo[5.2.1.02,6]dec-8-en-3-one

Conditions
ConditionsYield
With zinc(II) iodide In dichloromethane at 15℃; for 21h;95%
(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

isopropyl alcohol
67-63-0

isopropyl alcohol

(4S,5S)-5-hydroxymethyl-4-C-(1-hydroxy-1-methylethyl)tetrahydrofuran-2-one
136265-74-2

(4S,5S)-5-hydroxymethyl-4-C-(1-hydroxy-1-methylethyl)tetrahydrofuran-2-one

Conditions
ConditionsYield
for 48h; Irradiation;94%
With acetophenone for 18h; Irradiation;
(1R,2S,5R)-menthyl chloroformate
14602-86-9

(1R,2S,5R)-menthyl chloroformate

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

(1R,2S,5R)-menthyl [(5S)-2-oxo-2,5-dihydrofuran-5-yl]methyl carbonate
386744-36-1

(1R,2S,5R)-menthyl [(5S)-2-oxo-2,5-dihydrofuran-5-yl]methyl carbonate

Conditions
ConditionsYield
With pyridine In dichloromethane Cooling;93%
O-benzyl 2,2,2-trichloroacetimidate
81927-55-1

O-benzyl 2,2,2-trichloroacetimidate

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

γ-benzyloxymethyl-α,β-butenolide
72605-53-9

γ-benzyloxymethyl-α,β-butenolide

Conditions
ConditionsYield
With trifluorormethanesulfonic acid In dichloromethane at 0℃; for 4h; Inert atmosphere;93%
With trifluorormethanesulfonic acid In dichloromethane; cyclohexane at 0℃; for 4h; Inert atmosphere;
4,4'-dimethoxytrityl chloride
40615-36-9

4,4'-dimethoxytrityl chloride

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

(S)-5-(4,4'-dimethoxytrityloxymethyl)-5H-furan-2-one
252667-55-3

(S)-5-(4,4'-dimethoxytrityloxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
With pyridine for 3h;92%
(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

acetyl chloride
75-36-5

acetyl chloride

(-)-(S)-5-acetyloxymethyl-2(5H)-furanone
85846-83-9

(-)-(S)-5-acetyloxymethyl-2(5H)-furanone

Conditions
ConditionsYield
With pyridine In dichloromethane at 0℃; for 1h;92%
With pyridine In dichloromethane at 0℃; for 1h;92%
(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

trifluoroacetic anhydride
407-25-0

trifluoroacetic anhydride

(-)-(S)-5-trifluoroacetyloxymethyl-2(5H)-furanone
139230-95-8

(-)-(S)-5-trifluoroacetyloxymethyl-2(5H)-furanone

Conditions
ConditionsYield
for 6h;91%
(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

benzoyl chloride
98-88-4

benzoyl chloride

(5S)-5-(benzoyloxymethyl)-5H-furan-2-one
96086-02-1

(5S)-5-(benzoyloxymethyl)-5H-furan-2-one

Conditions
ConditionsYield
With pyridine In dichloromethane at 0℃; for 1h;86%
With pyridine In dichloromethane at 0℃; for 1h;86%
With pyridine In dichloromethane at 0℃; for 1h;85%
4-tert-butoxy-3,4-dihydro-2H-pyrrole 1-oxide

4-tert-butoxy-3,4-dihydro-2H-pyrrole 1-oxide

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

8-tert-butoxy-3-hydroxymethyl-hexahydro-furo[3,4-d]pyrrolo[1,2-b]isoxazol-1-one

8-tert-butoxy-3-hydroxymethyl-hexahydro-furo[3,4-d]pyrrolo[1,2-b]isoxazol-1-one

Conditions
ConditionsYield
In toluene Heating;86%
triisopropylsilyl chloride
13154-24-0

triisopropylsilyl chloride

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

(S)-(5-O-triisopropylsilanyloxymethyl)furan-2(5H)-one
848413-91-2

(S)-(5-O-triisopropylsilanyloxymethyl)furan-2(5H)-one

Conditions
ConditionsYield
With 1H-imidazole In dichloromethane at 20℃; for 18h;86%
Stage #1: (5S)-5-(hydroxymethyl)-5H-furan-2-one With 1H-imidazole In dichloromethane
Stage #2: triisopropylsilyl chloride In dichloromethane at 25℃;
65%
chlorotriisopropylsilane
6485-79-6

chlorotriisopropylsilane

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

(S)-(5-O-triisopropylsilanyloxymethyl)furan-2(5H)-one
848413-91-2

(S)-(5-O-triisopropylsilanyloxymethyl)furan-2(5H)-one

Conditions
ConditionsYield
With 1H-imidazole In dichloromethane at 20℃; for 18h;86%
(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

acetic anhydride
108-24-7

acetic anhydride

(-)-(S)-5-acetyloxymethyl-2(5H)-furanone
85846-83-9

(-)-(S)-5-acetyloxymethyl-2(5H)-furanone

Conditions
ConditionsYield
With pyridine In dichloromethane at 0℃; for 24h;83%
With pyridine In dichloromethane for 14h; Ambient temperature;79%
With pyridine; dmap In dichloromethane for 1.5h; Yield given;
(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

trityl chloride
76-83-5

trityl chloride

2,3-dideoxy-5-O-(triphenylmethyl)-D-glycero-pent-2-enono-1,4-lactone
76236-32-3

2,3-dideoxy-5-O-(triphenylmethyl)-D-glycero-pent-2-enono-1,4-lactone

Conditions
ConditionsYield
With pyridine at 70℃; for 16h; tritylation;83%
In pyridine65%
With pyridine 1.) 20 min, 2.) 72 h, room tempreature;64.7%
With pyridine In dichloromethane for 4h; Ambient temperature;50%
With pyridine In dichloromethane at 0℃; for 24h;40%
(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

1-Adamantanecarbonyl chloride
2094-72-6

1-Adamantanecarbonyl chloride

(-)-(S)-5-adamantanecarbonyloxymethyl-2(5H)-furanone
1071533-93-1

(-)-(S)-5-adamantanecarbonyloxymethyl-2(5H)-furanone

Conditions
ConditionsYield
With pyridine In dichloromethane at 20℃;83%
cyclopent-1-enecarboxylic acid
1560-11-8

cyclopent-1-enecarboxylic acid

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

(-)-R-4-(cyclopent-1-ene-1-carbonyloxymethyl)but-2-en-4-olide
162086-61-5

(-)-R-4-(cyclopent-1-ene-1-carbonyloxymethyl)but-2-en-4-olide

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane for 2h; Ambient temperature;82%
2-Methoxyethoxymethyl chloride
3970-21-6

2-Methoxyethoxymethyl chloride

(5S)-5-(hydroxymethyl)-5H-furan-2-one
78508-96-0

(5S)-5-(hydroxymethyl)-5H-furan-2-one

(S)-5-(2-methoxyethoxy)methoxymethyl-2(5H)-furanone

(S)-5-(2-methoxyethoxy)methoxymethyl-2(5H)-furanone

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 24h; Inert atmosphere;82%

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