As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
Cas:78508-96-0
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:78508-96-0
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so
Cas:78508-96-0
Min.Order:1 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
Cas:78508-96-0
Min.Order:1 Kilogram
FOB Price: $2.0 / 10.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:78508-96-0
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:78508-96-0
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:78508-96-0
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiry1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s
Cas:78508-96-0
Min.Order:1 Kilogram
FOB Price: $10.0 / 100.0
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:78508-96-0
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryBest quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
Cas:78508-96-0
Min.Order:0
Negotiable
Type:Manufacturers
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Cas:78508-96-0
Min.Order:0 Metric Ton
Negotiable
Type:Other
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:78508-96-0
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryfactory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Cas:78508-96-0
Min.Order:1 Kilogram
FOB Price: $18.0 / 20.0
Type:Trading Company
inquiryShandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
Cas:78508-96-0
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:78508-96-0
Min.Order:1 Metric Ton
FOB Price: $1.5
Type:Trading Company
inquiryAppearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea
Cas:78508-96-0
Min.Order:0
Negotiable
Type:Manufacturers
inquiryWe are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp
Cas:78508-96-0
Min.Order:1 Metric Ton
FOB Price: $1.0
Type:Trading Company
inquiryLower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe
Cas:78508-96-0
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryR & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates
Cas:78508-96-0
Min.Order:0
Negotiable
Type:Manufacturers
inquiryhigh qualityAppearance:white crystalline powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea
Cas:78508-96-0
Min.Order:0
Negotiable
Type:Manufacturers
inquiryOur clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS
Cas:78508-96-0
Min.Order:0
Negotiable
Type:Manufacturers
inquirybest seller Application:API
Cas:78508-96-0
Min.Order:0
Negotiable
Type:Manufacturers
inquiryAnsciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
Cas:78508-96-0
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiry(S)-(?)-5-Hydroxymethyl-2(5H)-furanone Application:(S)-( )-5-Hydroxymethyl-2(5H)-furanone
best seller Application:API
Cas:78508-96-0
Min.Order:0
Negotiable
Type:Trading Company
inquiryWe are committed to providing our customers with the best products and services at the most competitive prices.Appearance:clear light yellow liquid Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use
Cas:78508-96-0
Min.Order:0
Negotiable
Type:Trading Company
inquiry(S)-(-)-5-Hydroxymethyl-2(5H)-furanone cas 78508-96-0Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express
Cas:78508-96-0
Min.Order:0
Negotiable
Type:Other
inquiryfactory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Cas:78508-96-0
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryGood Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen
(S)-(?)-5-Hydroxymethyl-2(5H)-furanoneAppearance:white crystalline powder Storage:Shading, sealed, dry place. Package:aluminous bag Application:API Transportation:By express (Door to door) such as FEDEX, DHL, EMS for small amount. By air(airport to a
Cas:78508-96-0
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquirymethyl (2Z)-3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]acrylate
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
With sulfuric acid In methanol at 23℃; for 2h; | 97% |
With camphor-10-sulfonic acid In methanol at 20℃; | 95% |
With sulfuric acid In methanol at 20℃; for 2h; | 93% |
With hydrogenchloride In water; acetonitrile for 2.75h; Product distribution; Further Variations:; Reagents; | 84% |
With camphor-10-sulfonic acid at 25℃; for 3h; |
ethyl (R,Z)-3-(2′,2′-dimethyl-1′,3′-dioxolan-4′-yl)acrylate
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
With sulfuric acid In methanol for 0.5h; Ambient temperature; | 95% |
With sulfuric acid In methanol |
ethyl (Z)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)acrylate
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
With hydrogenchloride | 90% |
With hydrogenchloride In ethanol for 2h; Ambient temperature; | 81% |
With sulfuric acid |
2,3-dideoxy-5-O-(triphenylmethyl)-D-glycero-pent-2-enono-1,4-lactone
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
With hydrogenchloride In methanol for 2h; Ambient temperature; | 90% |
With hydrogenchloride; methanol |
methyl (S)-4,5-dihydroxy-4,5-O-isopropylidene-2-pentenoate
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
With sulfuric acid In methanol at 25℃; for 1h; | 90% |
With sulfuric acid; water In methanol at 20℃; for 2h; Cyclization; | 85% |
levoglucosenone
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
With dihydrogen peroxide In water at 50℃; for 10h; Baeyer-Villiger Ketone Oxidation; Inert atmosphere; Cooling with ice; | 84% |
Stage #1: levoglucosenone With Candida antarctica B lipase; dihydrogen peroxide In ethyl acetate at 40℃; for 8h; Baeyer-Villiger Ketone Oxidation; Green chemistry; Enzymatic reaction; Stage #2: In 1,4-dioxane at 20℃; for 8h; Catalytic behavior; Reagent/catalyst; Temperature; Concentration; Green chemistry; regioselective reaction; | 83% |
With dihydrogen peroxide In water at 0 - 50℃; for 1h; Baeyer-Villiger Ketone Oxidation; | 76% |
(5S)-5-(tert-butyldimethylsilanyloxymethyl)-5H-furan-2-one
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
With water; acetic acid In tetrahydrofuran at 24℃; for 22h; | 82% |
With acetic acid In tetrahydrofuran; water at 24℃; for 22h; | 82% |
levoglucosenone
A
(5S)-5-(hydroxymethyl)-5H-furan-2-one
B
(-)-(S)-5-formyloxymethyloxol-3-en-2one
Conditions | Yield |
---|---|
With dihydrogen peroxide In water at 50℃; for 10h; Baeyer-Villiger Ketone Oxidation; Inert atmosphere; Cooling with ice; Large scale; | A 71% B n/a |
With peracetic acid; dimethylsulfide; acetic acid 1.) RT, 2 d, 2.) 1 h; Multistep reaction. Title compound not separated from byproducts; | |
With Candida antarctica B lipase; dihydrogen peroxide In ethyl acetate at 40℃; for 8h; Catalytic behavior; Reagent/catalyst; Temperature; Concentration; Baeyer-Villiger Ketone Oxidation; Green chemistry; Enzymatic reaction; regioselective reaction; |
D-Ribono-1,4-lactone
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
With methyltrioxorhenium(VII) at 170 - 180℃; for 15h; Sealed tube; Inert atmosphere; | 70% |
Multi-step reaction with 2 steps 1: 1.) THF, 12 h, reflux, 2.) 7 d 2: 68 percent / 220 °C / 40 Torr View Scheme | |
Multi-step reaction with 2 steps 1: tetrahydrofuran / 12 h / Heating 2: 68 percent / 220 °C / 40 Torr View Scheme | |
With methyltrioxorhenium(VII) at 155℃; for 2h; Inert atmosphere; | 23.5 mg |
2,3-O-(ethoxymethylene)-D-ribonic acid γ-lactone
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
at 220℃; under 40 Torr; | 68% |
(+)-2,3-O-ethoxymethylene-D-ribonolactone
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
at 220℃; under 40 Torr; | 68% |
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
With N-fluorobis(benzenesulfon)imide; lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 1h; | 65% |
methyl (S)-4,5-dihydroxy-4,5-O-isopropylidene-2-pentenoate
A
(5S)-5-(hydroxymethyl)-5H-furan-2-one
B
ethyl (E)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)acrylate
Conditions | Yield |
---|---|
With sulfuric acid In methanol for 0.5h; Ambient temperature; | A 63% B n/a |
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
With phenanthrene In dichloromethane at 25 - 30℃; UV-irradiation; | 61% |
3-<(4'S)-2',2'-dimethyl-1',3'-dioxolan-4'-yl>prop-2-enoic acid ethyl ester
A
(5S)-5-(hydroxymethyl)-5H-furan-2-one
B
methyl (2E)-3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]acrylate
Conditions | Yield |
---|---|
With sulfuric acid In methanol for 0.5h; Ambient temperature; | A 60% B n/a |
A
tert-butyl 5-hydroxy-4-oxopentanoate
B
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
With adenosine In dichloromethane at 25 - 30℃; UV-irradiation; | A 51% B n/a |
levoglucosenone
A
(5S)-5-(hydroxymethyl)-5H-furan-2-one
B
2-deoxy-3-O-methyl-D-erythro-pentono-1,4-lactone
Conditions | Yield |
---|---|
With dihydrogen peroxide; sodium hydroxide In methanol at 18℃; for 408h; | A 13% B 4% |
(-)-(S)-5-acetyloxymethyl-2(5H)-furanone
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
With hydrogenchloride In methanol at 5℃; for 18h; Yield given; |
tert-butyl 6-O-acetyl-3,4-dideoxy-α-D-glycero-hex-3-enopyranosid-2-ulose
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
With peracetic acid for 12h; |
2-Bromo-2-deoxy-D-arabinono-γ-lactone
A
(5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran
B
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
With hydrogen; palladium on activated charcoal In ethanol at 20℃; under 760 Torr; |
(3R/S,4S)-5-Hydroxy-4-phenylsulfinyl-4-pentanolide
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
With calcium carbonate In toluene for 3h; Heating; Yield given; |
orthoformic acid triethyl ester
D-Ribono-1,4-lactone
A
protoanemonin
B
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
1.) THF, reflux; 2.) 220 deg C, 18 Hgmm; Multistep reaction; |
D-Ribono-1,4-lactone
A
(5S)-5-(hydroxymethyl)-5H-furan-2-one
B
(S)-(-)-γ-bromometil-α,β-butenolide
Conditions | Yield |
---|---|
Yield given. Multistep reaction; |
1-(2-deoxy-2-iodo-β-D-ribofuranosyl)uracil
A
2,2'-Anhydrouridine
B
(5S)-5-(hydroxymethyl)-5H-furan-2-one
F
2-deoxy-D-ribonolactone
Conditions | Yield |
---|---|
In water-d2 for 4h; Product distribution; Mechanism; Irradiation; var. solvents, in the presence of O2, also <1'-D>-2'α-iodo-2'-deoxyuridine, other deoxyoligonucleotides; | A 2.0 % Spectr. B 2.0 % Spectr. C 1.0 % Spectr. D 4.0 % Spectr. E 13 % Spectr. F 1.0 % Spectr. |
5-({[tert-butyl(dimethyl)silyl]oxy}methyl)-5H-furan-2-one
A
(5S)-5-(hydroxymethyl)-5H-furan-2-one
B
(R)-(+)-5-(hydroxymethyl)furan-2(5H)-one
Conditions | Yield |
---|---|
With pyridine hydrogenfluoride In tetrahydrofuran at 0℃; for 16h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; |
tert-butyl (4R)-4,5-O-isopropylidene-3,4,5-trihydroxypentanoate
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 82 percent / CH3COOH / tetrahydrofuran; H2O / 22 h / 24 °C View Scheme | |
Multi-step reaction with 3 steps 1: 50 percent aq. CF3COOH / 2 h / 90 - 95 °C 2: 1.)t-BuMe2SiCl; 2.) SOCl2, pyridine / 1.) CH2Cl2, 20 deg C., 16h; 2.) CH2Cl2, 24 deg C, 22h 3: 82 percent / H2O, AcOH / tetrahydrofuran / 22 h / 24 °C View Scheme |
(2E)-3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]prop-2-en-1-ol
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 99 percent / Et3N / CH2Cl2 / 1 h / 20 °C 2: 84 percent / HCl / H2O; acetonitrile / 2.75 h View Scheme |
tert-butyl 2,4,6-tri-O-acetyl-3-deoxy-α-D-erythro-hex-2-enopyranoside
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: K2CO3 / methanol / 1 h 2: pyridine, dimethylaminopyridine / CH2Cl2 / 1 h 3: 40percent aq. AcOOH / 12 h View Scheme |
tert-butyl 3,4-dideoxy-α-D-glycero-hex-3-enopyranosid-2-ulose
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: pyridine, dimethylaminopyridine / CH2Cl2 / 1 h 2: 40percent aq. AcOOH / 12 h View Scheme |
2,3,4,6-tetra-O-acetyl-1,5-anhydro-D-arabinohex-1-enopyranose
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 87 percent / BF3*Et2O / CH2Cl2 / 72 h 2: K2CO3 / methanol / 1 h 3: pyridine, dimethylaminopyridine / CH2Cl2 / 1 h 4: 40percent aq. AcOOH / 12 h View Scheme |
(5S)-5-(hydroxymethyl)-5H-furan-2-one
tert-butyldimethylsilyl chloride
(5S)-5-(tert-butyldimethylsilanyloxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
With 1H-imidazole In dichloromethane at 0 - 20℃; for 1h; | 100% |
With 1H-imidazole In dichloromethane at 0 - 23℃; for 1h; | 99% |
With 1H-imidazole In dichloromethane at 20℃; for 3h; | 98% |
(5S)-5-(hydroxymethyl)-5H-furan-2-one
tetradecanoyl chloride
5-O-tetradecanoyl-2,3-didehydro-2,3-dideoxy-D-glycero-pentono-1,4-lactone
Conditions | Yield |
---|---|
With pyridine; dmap In dichloromethane for 24h; Ambient temperature; | 97% |
(5S)-5-(hydroxymethyl)-5H-furan-2-one
tert-butylchlorodiphenylsilane
(5S)-5-(tert-butyldiphenylsiloxymethyl)-2(5H)-furanone
Conditions | Yield |
---|---|
With 1H-imidazole In dichloromethane at 0℃; for 0.75h; | 97% |
With ammonium nitrate In N,N-dimethyl-formamide at 0 - 25℃; for 12.5h; | 95% |
With dmap | 94% |
(5S)-5-(hydroxymethyl)-5H-furan-2-one
(+/-)-3-tert-butyldimethylsilyloxy-1-cyclopentane-1-carboxylic acid
(-)-R-4-(3-tert-butyldimethylsilyloxycyclopent-1-ene-1-carbonyloxymethyl)but-2-en-4-olide
Conditions | Yield |
---|---|
With dicyclohexyl-carbodiimide In dichloromethane | 96% |
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0℃; for 2h; | 96% |
(5S)-5-(hydroxymethyl)-5H-furan-2-one
(5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran
Conditions | Yield |
---|---|
With hydrogen; palladium on activated charcoal In ethanol for 4h; Ambient temperature; | 96% |
With palladium 10% on activated carbon; hydrogen In ethyl acetate at 20℃; | 90% |
With palladium 10% on activated carbon; hydrogen In ethyl acetate at 20℃; | 86% |
3,4-dihydro-2H-pyran
(5S)-5-(hydroxymethyl)-5H-furan-2-one
(4S)-4-hydroxy-5-tetrahydropyranyloxy-2-pentenoic acid γ-lactone
Conditions | Yield |
---|---|
With camphor-10-sulfonic acid In tetrahydrofuran at 10℃; for 15h; | 95% |
With camphor-10-sulfonic acid | 93% |
With toluene-4-sulfonic acid In dichloromethane at 23℃; for 8h; | 78% |
With toluene-4-sulfonic acid In dichloromethane at 20℃; for 8h; | 78% |
(5S)-5-(hydroxymethyl)-5H-furan-2-one
pivaloyl chloride
(-)-(S)-5-pivaloyloxymethyl-2(5H)-furanone
Conditions | Yield |
---|---|
With pyridine In dichloromethane at 0℃; for 24h; Esterification; | 95% |
With pyridine; dmap In dichloromethane for 29h; Ambient temperature; | 89% |
With pyridine In dichloromethane at 23℃; for 12h; | 81% |
With pyridine In dichloromethane at 0 - 20℃; | 81% |
(5S)-5-(hydroxymethyl)-5H-furan-2-one
cyclopenta-1,3-diene
Conditions | Yield |
---|---|
With zinc(II) iodide In dichloromethane at 15℃; for 21h; | 95% |
(5S)-5-(hydroxymethyl)-5H-furan-2-one
isopropyl alcohol
(4S,5S)-5-hydroxymethyl-4-C-(1-hydroxy-1-methylethyl)tetrahydrofuran-2-one
Conditions | Yield |
---|---|
for 48h; Irradiation; | 94% |
With acetophenone for 18h; Irradiation; |
(1R,2S,5R)-menthyl chloroformate
(5S)-5-(hydroxymethyl)-5H-furan-2-one
(1R,2S,5R)-menthyl [(5S)-2-oxo-2,5-dihydrofuran-5-yl]methyl carbonate
Conditions | Yield |
---|---|
With pyridine In dichloromethane Cooling; | 93% |
O-benzyl 2,2,2-trichloroacetimidate
(5S)-5-(hydroxymethyl)-5H-furan-2-one
γ-benzyloxymethyl-α,β-butenolide
Conditions | Yield |
---|---|
With trifluorormethanesulfonic acid In dichloromethane at 0℃; for 4h; Inert atmosphere; | 93% |
With trifluorormethanesulfonic acid In dichloromethane; cyclohexane at 0℃; for 4h; Inert atmosphere; |
4,4'-dimethoxytrityl chloride
(5S)-5-(hydroxymethyl)-5H-furan-2-one
(S)-5-(4,4'-dimethoxytrityloxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
With pyridine for 3h; | 92% |
(5S)-5-(hydroxymethyl)-5H-furan-2-one
acetyl chloride
(-)-(S)-5-acetyloxymethyl-2(5H)-furanone
Conditions | Yield |
---|---|
With pyridine In dichloromethane at 0℃; for 1h; | 92% |
With pyridine In dichloromethane at 0℃; for 1h; | 92% |
(5S)-5-(hydroxymethyl)-5H-furan-2-one
trifluoroacetic anhydride
(-)-(S)-5-trifluoroacetyloxymethyl-2(5H)-furanone
Conditions | Yield |
---|---|
for 6h; | 91% |
(5S)-5-(hydroxymethyl)-5H-furan-2-one
benzoyl chloride
(5S)-5-(benzoyloxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
With pyridine In dichloromethane at 0℃; for 1h; | 86% |
With pyridine In dichloromethane at 0℃; for 1h; | 86% |
With pyridine In dichloromethane at 0℃; for 1h; | 85% |
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
In toluene Heating; | 86% |
triisopropylsilyl chloride
(5S)-5-(hydroxymethyl)-5H-furan-2-one
(S)-(5-O-triisopropylsilanyloxymethyl)furan-2(5H)-one
Conditions | Yield |
---|---|
With 1H-imidazole In dichloromethane at 20℃; for 18h; | 86% |
Stage #1: (5S)-5-(hydroxymethyl)-5H-furan-2-one With 1H-imidazole In dichloromethane Stage #2: triisopropylsilyl chloride In dichloromethane at 25℃; | 65% |
chlorotriisopropylsilane
(5S)-5-(hydroxymethyl)-5H-furan-2-one
(S)-(5-O-triisopropylsilanyloxymethyl)furan-2(5H)-one
Conditions | Yield |
---|---|
With 1H-imidazole In dichloromethane at 20℃; for 18h; | 86% |
(5S)-5-(hydroxymethyl)-5H-furan-2-one
acetic anhydride
(-)-(S)-5-acetyloxymethyl-2(5H)-furanone
Conditions | Yield |
---|---|
With pyridine In dichloromethane at 0℃; for 24h; | 83% |
With pyridine In dichloromethane for 14h; Ambient temperature; | 79% |
With pyridine; dmap In dichloromethane for 1.5h; Yield given; |
(5S)-5-(hydroxymethyl)-5H-furan-2-one
trityl chloride
2,3-dideoxy-5-O-(triphenylmethyl)-D-glycero-pent-2-enono-1,4-lactone
Conditions | Yield |
---|---|
With pyridine at 70℃; for 16h; tritylation; | 83% |
In pyridine | 65% |
With pyridine 1.) 20 min, 2.) 72 h, room tempreature; | 64.7% |
With pyridine In dichloromethane for 4h; Ambient temperature; | 50% |
With pyridine In dichloromethane at 0℃; for 24h; | 40% |
(5S)-5-(hydroxymethyl)-5H-furan-2-one
1-Adamantanecarbonyl chloride
(-)-(S)-5-adamantanecarbonyloxymethyl-2(5H)-furanone
Conditions | Yield |
---|---|
With pyridine In dichloromethane at 20℃; | 83% |
cyclopent-1-enecarboxylic acid
(5S)-5-(hydroxymethyl)-5H-furan-2-one
(-)-R-4-(cyclopent-1-ene-1-carbonyloxymethyl)but-2-en-4-olide
Conditions | Yield |
---|---|
With dmap; dicyclohexyl-carbodiimide In dichloromethane for 2h; Ambient temperature; | 82% |
2-Methoxyethoxymethyl chloride
(5S)-5-(hydroxymethyl)-5H-furan-2-one
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 24h; Inert atmosphere; | 82% |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View