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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay (Ursolic acid) 98%min 98.22% ----------------------------------------------------------------

High purity 78920-10-2 4-n-Propyl hydroxy furanone

Cas:78920-10-2

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Trading Company

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 5-hydroxy-4-propylfuran-2(5H)-one

Cas:78920-10-2

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% 2(5H)-Furanone,5-hydroxy-4-propyl- 78920-10-2 ISO Manufacturer

Cas:78920-10-2

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

5-Hydroxy-4-propyl-2(5H)-furanone

Cas:78920-10-2

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

5-Hydroxy-4-N-propylfuran-2-one

Cas:78920-10-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

2(5H)-FURANONE, 5-HYDROXY-4-PROPYL-

Cas:78920-10-2

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 78920-10-2 with competitive price

Cas:78920-10-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2(5H)-Furanone,5-hydroxy-4-propyl- 78920-10-2

Cas:78920-10-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

2(5H)-FURANONE, 5-HYDROXY-4-PROPYL- CAS:78920-10-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quali

2(5H)-FURANONE, 5-HYDROXY-4-PROPYL- CAS:78920-10-2

Cas:78920-10-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:78920-10-2

Cas:78920-10-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2(5H)-Furanone,5-hydroxy-4-propyl-

Cas:78920-10-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Triumph International Development Limilted

Appearance:solid or liquid Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common products:Sea/Air/Cou

5-hydroxy-4-n-propylfuran-2-one

Cas:78920-10-2

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

2-hydroxy-3-propyl-2H-furan-5-one cas 78920-10-2

Cas:78920-10-2

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Professional supplier of 2-hydroxy-3-propyl-2h-furan-5-one CAS NO.78920-10-2

Cas:78920-10-2

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

2(5H)-FURANONE, 5-HYDROXY-4-PROPYL-

Cas:78920-10-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2(5H)-Furanone,5-hydroxy-4-propyl-

Cas:78920-10-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

2-hydroxy-3-propyl-2H-furan-5-one

Cas:78920-10-2

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Top Purity 2(5H)-FURANONE, 5-HYDROXY-4-PROPYL-

Cas:78920-10-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Professional supplier of 2-hydroxy-3-propyl-2h-furan-5-one CAS NO.78920-10-2

Cas:78920-10-2

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

2(5H)-FURANONE, 5-HYDROXY-4-PROPYL-

Cas:78920-10-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

2(5H)-FURANONE, 5-HYDROXY-4-PROPYL-

Cas:78920-10-2

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Professional supplier of 2-hydroxy-3-propyl-2h-furan-5-one CAS NO.78920-10-2

Cas:78920-10-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Professional supplier of 2-hydroxy-3-propyl-2h-furan-5-one CAS NO.78920-10-2

Cas:78920-10-2

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

5-Hydroxy-4-propyl-2(5H)-furanone

Cas:78920-10-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

2(5H)-FURANONE, 5-HYDROXY-4-PROPYL-

Cas:78920-10-2

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

Professional supplier of 2-hydroxy-3-propyl-2h-furan-5-one CAS NO.78920-10-2

Cas:78920-10-2

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

5-Hydroxy-4-N-Propylfuran-2-one

Cas:78920-10-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

5-hydroxy-4-n-propylfuran-2-one

Cas:78920-10-2

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

with high qualityAppearance:white powder Storage:Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Package:25kg/drum Application:as intermediates Transportation:by courier, air or sea Port:At any port from China

5-hydroxy-4-propylfuran-2(5H)-one 78920-10-2 Pharmaceutical Intermediates

Cas:78920-10-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec 2-hydroxy-3-propyl-2H-furan-5-one 25g

Cas:78920-10-2

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

pentanal
110-62-3

pentanal

Glyoxilic acid
298-12-4

Glyoxilic acid

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

Conditions
ConditionsYield
With morpholine In n-heptane at 40.1 - 41.7℃; for 18h; Industrial scale;96.3%
Stage #1: Glyoxilic acid With morpholine In water at 10 - 30℃; for 5h; Large scale;
Stage #2: pentanal In water at 40 - 45℃; for 18h; Large scale;
Stage #3: With hydrogenchloride In water at 25 - 30℃; for 4h; Large scale;
95.8%
In n-heptane; water at 10 - 45℃; for 7h; Temperature; Large scale;92.5%
pentanal
110-62-3

pentanal

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

Conditions
ConditionsYield
Stage #1: Glyoxilic acid With morpholine In n-heptane; water at 20℃; for 1h;
Stage #2: pentanal In n-heptane; water at 43℃; for 20h;
Stage #3: With hydrogenchloride In n-heptane; water at 20℃; for 2h;
90.8%
pentanal
110-62-3

pentanal

2,2-dihydroxyacetic acid
563-96-2

2,2-dihydroxyacetic acid

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

Conditions
ConditionsYield
With morpholin hydrochloride In 1,4-dioxane; water 1) RT, 1 h, 2) 24 h, reflux;70%
5-Ethoxy-4-propyl-5H-furan-2-one
78920-15-7

5-Ethoxy-4-propyl-5H-furan-2-one

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

Conditions
ConditionsYield
With hydrogenchloride for 0.25h; Heating; Yield given;
5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

4-propyl-5H-furan-2-one
21963-27-9

4-propyl-5H-furan-2-one

Conditions
ConditionsYield
With sodium tetrahydroborate In methanol at 20℃; for 1h;100%
With sodium tetrahydroborate In ethanol for 2h; Inert atmosphere; Large scale;90%
With methanol; sodium tetrahydroborate at 20℃; for 1h;90.15%
With sodium tetrahydroborate In toluene at 20℃; for 4h; Reagent/catalyst; Inert atmosphere;80%
(S)-2-aminobutyric acid methyl ester hydrochloride

(S)-2-aminobutyric acid methyl ester hydrochloride

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

methyl (2S)-2-(2-hydroxy-5-oxo-3-propyl-2,5-dihydro-1H-pyrrol-1-yl)butanoate

methyl (2S)-2-(2-hydroxy-5-oxo-3-propyl-2,5-dihydro-1H-pyrrol-1-yl)butanoate

Conditions
ConditionsYield
With triethylamine In toluene at 20℃; for 3h; Time; Large scale;90%
(S)-2-amino-butanamide hydrochloride
53726-14-0

(S)-2-amino-butanamide hydrochloride

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

(2S)-2-(2-hydroxy-5-oxo-3-propyl-2,5-dihydro-1H-pyrrole-1-yl)butanamide

(2S)-2-(2-hydroxy-5-oxo-3-propyl-2,5-dihydro-1H-pyrrole-1-yl)butanamide

Conditions
ConditionsYield
Stage #1: (S)-2-amino-butanamide hydrochloride With ammonia In isopropyl alcohol pH=9 - 10;
Stage #2: 5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one In isopropyl alcohol at 30 - 40℃;
88.8%
at 20℃;65.3%
5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

(2S)-4,5-dehydro-(2-oxo-4-n-propyl-1-pyrrolidinyl)-2-butanamide
357338-13-7

(2S)-4,5-dehydro-(2-oxo-4-n-propyl-1-pyrrolidinyl)-2-butanamide

Conditions
ConditionsYield
With sodium tetrahydroborate; sodium hydroxide In water; isopropyl alcohol at 5 - 25℃; for 1h;88.3%
Stage #1: (S)-2-amino-butanamide; 5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one In toluene at 18℃; for 2.5h;
Stage #2: With sodium hydroxide In water; toluene for 1h;
Stage #3: With sodium hydroxide; acetic acid more than 3 stages;
3.4%
Stage #1: (S)-2-amino-butanamide; 5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one In ethanol at 40℃; for 0.0833333h;
Stage #2: With sodium tetrahydroborate; ammonia In ethanol at 40℃; for 0.166667h;
Stage #3: With acetic acid In ethanol at 105℃; for 0.15h;
L-2-aminobutyric acid
1492-24-6

L-2-aminobutyric acid

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

(S)-2-(4-propyl-1,5-dihydropyrrole-2-one)butanoic acid

(S)-2-(4-propyl-1,5-dihydropyrrole-2-one)butanoic acid

Conditions
ConditionsYield
Stage #1: L-2-aminobutyric acid With sodium methylate In methanol at 0℃; for 0.5h;
Stage #2: 5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one In methanol at 20℃; for 0.5h; Further stages;
86.7%
Stage #1: L-2-aminobutyric acid With triethylamine In methanol at 20℃; for 0.333333h;
Stage #2: 5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one In methanol at 20℃; for 1.5h;
Stage #3: With sodium tetrahydroborate In methanol at 0 - 10℃; for 0.333333h; Heating;
78.9%
5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

methyl iodide
74-88-4

methyl iodide

methyl (Z)-3-propyl-4-oxo-2-butenoate

methyl (Z)-3-propyl-4-oxo-2-butenoate

Conditions
ConditionsYield
Stage #1: 5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one With sodium hydride In N,N,N,N,N,N-hexamethylphosphoric triamide at 0℃; for 1h;
Stage #2: methyl iodide In N,N,N,N,N,N-hexamethylphosphoric triamide at 0 - 20℃; for 0.25h;
82%
L-2-aminobutanamide acetate

L-2-aminobutanamide acetate

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

(2S)-2-((5-oxyl-3-propyl-2,5-dihydrofuran-2-yl)amino)butanamide

(2S)-2-((5-oxyl-3-propyl-2,5-dihydrofuran-2-yl)amino)butanamide

Conditions
ConditionsYield
With ammonia In methanol at 30 - 40℃; for 3h; pH=9 - 10; Large scale;80.3%
5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

C10H16N2O2

C10H16N2O2

Conditions
ConditionsYield
In isopropyl alcohol at 30℃; for 3h;80%
(S)-2-amino-butanamide hydrochloride
53726-14-0

(S)-2-amino-butanamide hydrochloride

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

(2S)-2-((5-oxyl-3-propyl-2,5-dihydrofuran-2-yl)amino)butanamide

(2S)-2-((5-oxyl-3-propyl-2,5-dihydrofuran-2-yl)amino)butanamide

Conditions
ConditionsYield
With ammonia In methanol at 20 - 30℃; for 2h; pH=9 - 10; Large scale;79.8%
(S)-2-aminobutyric acid methyl ester hydrochloride
7682-18-0, 26815-92-9, 56545-22-3, 85774-09-0

(S)-2-aminobutyric acid methyl ester hydrochloride

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

methyl (2S)-2-(2-oxo-4-propyl-2,5-dihydropyrrol-1-yl)butyrate

methyl (2S)-2-(2-oxo-4-propyl-2,5-dihydropyrrol-1-yl)butyrate

Conditions
ConditionsYield
Stage #1: (S)-2-aminobutyric acid methyl ester hydrochloride With triethylamine In methanol at 0℃; for 0.5h;
Stage #2: 5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one In methanol at 20℃; for 0.5h; Further stages;
76.3%
L-2-aminobutanamide tartaric acid
868134-59-2

L-2-aminobutanamide tartaric acid

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

(2S)-2-((5-oxyl-3-propyl-2,5-dihydrofuran-2-yl)amino)butanamide

(2S)-2-((5-oxyl-3-propyl-2,5-dihydrofuran-2-yl)amino)butanamide

Conditions
ConditionsYield
With ammonia In isopropyl alcohol at 40 - 50℃; for 2h; pH=9 - 10; Large scale;71.7%
1-[2-(methoxymethyl)-6-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl]methanamine
1403586-73-1

1-[2-(methoxymethyl)-6-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl]methanamine

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

1-[[2-(methoxymethyl)-6-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl]methyl]-3-propyl-2H-pyrrol-5-one

1-[[2-(methoxymethyl)-6-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl]methyl]-3-propyl-2H-pyrrol-5-one

Conditions
ConditionsYield
Stage #1: 1-[2-(methoxymethyl)-6-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl]methanamine; 5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one In methanol at 20℃; for 3.5h;
Stage #2: With sodium tetrahydroborate In methanol at 0℃; for 1h;
Stage #3: With acetic acid In methanol at 20℃;
30%
ethanol
64-17-5

ethanol

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

5-Ethoxy-4-propyl-5H-furan-2-one
78920-15-7

5-Ethoxy-4-propyl-5H-furan-2-one

Conditions
ConditionsYield
With hydrogenchloride for 12h; Heating;
(S)-3-acetyl-4-isopropyl-1,3-thiazolidine-2-thione
101979-45-7

(S)-3-acetyl-4-isopropyl-1,3-thiazolidine-2-thione

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

3-((2,5-dihydro-3-propyl-5-oxo-2(R)-furanyl)acetyl)-4(S)-isopropyl-1,3-thiazolidine-2-thione

3-((2,5-dihydro-3-propyl-5-oxo-2(R)-furanyl)acetyl)-4(S)-isopropyl-1,3-thiazolidine-2-thione

Conditions
ConditionsYield
With 1-ethyl-piperidine; tin(II) trifluoromethanesulfonate 1.) THF, from -50 to -40 deg C, 3 h, 2.) THF, from -5 to 0 deg C, 2 h; Yield given. Multistep reaction;
5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

5-hydroxy-4-propyldihydrofuran-2-one
357338-44-4

5-hydroxy-4-propyldihydrofuran-2-one

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In ethyl acetate at 25℃; under 1810.02 Torr; for 2h;
With 5%-palladium/activated carbon; hydrogen In Isopropyl acetate at 20 - 25℃; under 1125.11 - 1875.19 Torr; for 2h; Solvent; Temperature; Pressure; Sealed tube;
With 5%-palladium/activated carbon; hydrogen In ethyl acetate at 25 - 30℃; under 1500.15 - 2250.23 Torr; for 2.5h; Solvent; Temperature; Pressure; Sealed tube;
5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

N-Fmoc-2-aminobutyric amide Rink resin

N-Fmoc-2-aminobutyric amide Rink resin

A

brivaracetam
357336-20-0

brivaracetam

B

((2S)-2-[(4S)-2-oxo-4-propyltetrahydro-1H-pyrrol-1-yl]butanamide)

((2S)-2-[(4S)-2-oxo-4-propyltetrahydro-1H-pyrrol-1-yl]butanamide)

Conditions
ConditionsYield
Multistep reaction;
5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

5-Ethoxy-4-propyl-dihydro-furan-2-one
78920-25-9

5-Ethoxy-4-propyl-dihydro-furan-2-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: HCl(g) / 12 h / Heating
2: 88 percent / H2 / 10percent Pd-C / ethanol / 4 h / 760 Torr
View Scheme
5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

A

brivaracetam
357336-20-0

brivaracetam

B

((2S)-2-[(4S)-2-oxo-4-propyltetrahydro-1H-pyrrol-1-yl]butanamide)

((2S)-2-[(4S)-2-oxo-4-propyltetrahydro-1H-pyrrol-1-yl]butanamide)

Conditions
ConditionsYield
Stage #1: (S)-2-amino-butanamide; 5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one In isopropyl alcohol at 15 - 30℃; for 2h;
Stage #2: With hydrogen; acetic acid; 5%-palladium/activated carbon In isopropyl alcohol at 40℃; under 150.015 - 375.038 Torr; for 20h; Product distribution / selectivity;
Stage #1: (S)-2-amino-butanamide; 5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one In isopropyl alcohol at 30℃; for 2h;
Stage #2: With 5%-palladium/activated carbon; hydrogen; acetic acid In isopropyl alcohol at 40℃; under 150.015 - 375.038 Torr; for 20h;
(R)-1-phenyl-ethyl-amine
3886-69-9

(R)-1-phenyl-ethyl-amine

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

5-hydroxy-1-[1-((R)-phenyl)-ethyl]-4-n-propyl-1,5-dihydro-pyrrol-2-one
1314556-95-0

5-hydroxy-1-[1-((R)-phenyl)-ethyl]-4-n-propyl-1,5-dihydro-pyrrol-2-one

Conditions
ConditionsYield
In isopropyl alcohol at 20℃; for 1h;
In isopropyl alcohol at 20℃; for 1h;
In isopropyl alcohol at 20℃; for 1h;
(S)-1-phenyl-ethylamine
2627-86-3

(S)-1-phenyl-ethylamine

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

5-hydroxy-1-[1-((S)-phenyl)-ethyl]-4-n-propyl-1,5-dihydro-pyrrol-2-one
1314556-94-9

5-hydroxy-1-[1-((S)-phenyl)-ethyl]-4-n-propyl-1,5-dihydro-pyrrol-2-one

Conditions
ConditionsYield
In isopropyl alcohol at 20℃; for 1h;
In isopropyl alcohol at 20℃; for 1h;
In isopropyl alcohol at 20℃;
In isopropyl alcohol at 20℃; for 1h;
(2S)-2-phenylglycinol
20989-17-7

(2S)-2-phenylglycinol

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

5-hydroxy-1-(2-hydroxy-1-(S)-phenyl-ethyl)-4-n-propyl-1,5-dihydro-pyrrol-2-one
1314557-00-0

5-hydroxy-1-(2-hydroxy-1-(S)-phenyl-ethyl)-4-n-propyl-1,5-dihydro-pyrrol-2-one

Conditions
ConditionsYield
In methanol at 20℃; for 1h;
5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

(R,S)-3-n-propyl-4-aminobutyric acid
130912-49-1

(R,S)-3-n-propyl-4-aminobutyric acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: ammonia / methanol / 1.5 h / 20 °C
2: hydrogen / palladium 10% on activated carbon / methanol / 3677.86 Torr / autoclave
View Scheme
5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

(3S)-3-propyl-4-((S)-1'-phenylethylamino)butanoic acid
1314557-03-3

(3S)-3-propyl-4-((S)-1'-phenylethylamino)butanoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: isopropyl alcohol / 1 h / 20 °C
2: hydrogen / palladium 10% on activated carbon / isopropyl alcohol / 2206.72 Torr / autoclave
View Scheme
Multi-step reaction with 2 steps
1: isopropyl alcohol / 1 h / 20 °C
2: hydrogen / palladium 10% on activated carbon / isopropyl alcohol / 2206.72 Torr / Autoclave
View Scheme
Multi-step reaction with 2 steps
1: isopropyl alcohol / 1 h / 20 °C
2: hydrogen / palladium 10% on activated carbon / isopropyl alcohol / 2206.72 Torr / Parr autoclave reactor
View Scheme
5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

(3R)-3-propyl-4-((S)-1'-phenylethylamino)butanoic acid
1314557-04-4

(3R)-3-propyl-4-((S)-1'-phenylethylamino)butanoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: isopropyl alcohol / 1 h / 20 °C
2: hydrogen / palladium 10% on activated carbon / isopropyl alcohol / 2206.72 Torr / autoclave
View Scheme
Multi-step reaction with 2 steps
1: isopropyl alcohol / 1 h / 20 °C
2: hydrogen / palladium 10% on activated carbon / isopropyl alcohol / 2206.72 Torr / Autoclave
View Scheme
Multi-step reaction with 2 steps
1: isopropyl alcohol / 1 h / 20 °C
2: hydrogen / palladium 10% on activated carbon / isopropyl alcohol / 2206.72 Torr / Parr autoclave reactor
View Scheme
5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

(3R)-3-propyl-4-((R)-1'-phenylethylamino)butanoic acid
1314557-05-5

(3R)-3-propyl-4-((R)-1'-phenylethylamino)butanoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: isopropyl alcohol / 1 h / 20 °C
2: hydrogen / palladium 10% on activated carbon / isopropyl alcohol / 2206.72 Torr / autoclave
View Scheme
Multi-step reaction with 2 steps
1: isopropyl alcohol / 1 h / 20 °C
2: hydrogen / palladium 10% on activated carbon / isopropyl alcohol / 2206.72 Torr / Autoclave
View Scheme
Multi-step reaction with 2 steps
1: isopropyl alcohol / 1 h / 20 °C
2: hydrogen / palladium 10% on activated carbon / isopropyl alcohol / 2206.72 Torr / Parr autoclave reactor
View Scheme
5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one
78920-10-2

5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one

(3S)-3-propyl-4-((R)-1'-phenylethylamino)butanoic acid
1314557-08-8

(3S)-3-propyl-4-((R)-1'-phenylethylamino)butanoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: isopropyl alcohol / 1 h / 20 °C
2: hydrogen / palladium 10% on activated carbon / isopropyl alcohol / 2206.72 Torr / autoclave
View Scheme
Multi-step reaction with 2 steps
1: isopropyl alcohol / 1 h / 20 °C
2: hydrogen / palladium 10% on activated carbon / isopropyl alcohol / 2206.72 Torr / Autoclave
View Scheme
Multi-step reaction with 2 steps
1: isopropyl alcohol / 1 h / 20 °C
2: hydrogen / palladium 10% on activated carbon / isopropyl alcohol / 2206.72 Torr / Parr autoclave reactor
View Scheme

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