Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
Cas:81409-90-7
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryOur service: 1.We have experience in exporting Pharmaceutical intermediates . 2.Professional packing with professional materials 3. We have products in stock, and we will deliver them soon when your PO arrived. Meanwhile we will give you the trackin
Cas:81409-90-7
Min.Order:1 Gram
Negotiable
Type:Other
inquiryBeluga chemical professional supply P2NP CAS:705-60-2 1-Phenyl-2-nitropropene Why choose Beluga chemical 1. Beluga Chemical has a professional RESEARCH and development team and strong technical force to ensure technical support and research capab
Items Standard Result Appearance White or almost white crystalline powder Conform Identity
Cas:81409-90-7
Min.Order:1 Gram
FOB Price: $100.0 / 500.0
Type:Manufacturers
inquiryT he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality service Appearance:White
The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:81409-90-7
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiryDayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:81409-90-7
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquirychengdu and import and export trade co., LTD., who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do res
Founded in 2014, Kono Chem Co., Ltd is an export-oriented production enterprise supported by the State Department of Commerce. Kono Chem covers an area of 312,000 square meters, with scientific and technological personnel accounting for more than 35%
Cas:81409-90-7
Min.Order:1 Kilogram
FOB Price: $99.0 / 100.0
Type:Other
inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:81409-90-7
Min.Order:10 Gram
FOB Price: $146.0 / 176.0
Type:Trading Company
inquiry1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W
Cas:81409-90-7
Min.Order:1 Metric Ton
FOB Price: $20.0 / 30.0
Type:Trading Company
inquiryCAS 81409-90-7 Name Cabergoline Appearance White powder Application For the treatment of primary or pituitary tumor caused by high prolactin disease
1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:81409-90-7
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryWe are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery
Cas:81409-90-7
Min.Order:10 Gram
FOB Price: $0.35
Type:Trading Company
inquiryWe can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C
Cas:81409-90-7
Min.Order:1 Gram
Negotiable
Type:Trading Company
inquiryWe generally use secure shipping methods that do not require you to do any customs clearance. Free shipping to your address without worrying about any customs issues. We have a professional customs clearance team to 100% guarantee the safe delivery o
Cas:81409-90-7
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Our Advantage 1. Rich experience We specialize in this filed for many years, our APIs exported to all over the world and and we established long friendly relations of cooperation with our clients. 2. Great quality,purity and favorable Good qual
Cas:81409-90-7
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryCabergoline CAS: 81409-90-7 Specification mp 102-104°c storage temp. store at +4°c cas database reference 81409-90-7(cas database reference) Welcome to contact us to get complete COA. Shanghai Lon
Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter
Our advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We have s
Hubei Lidu New Materials Technology Co. , Ltd. is located in No. 12,3C Industrial Park, Zhongxiang Economic Development Zone, Hubei Province. The company is committed to fine chemical raw materials, pharmaceutical intermediates and other production,
1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie
Cas:81409-90-7
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect. Our products has been exported to America, Australia, Brazil, the Europe, Middle East and other
Cas:81409-90-7
Min.Order:1 Kilogram
FOB Price: $3.0 / 5.0
Type:Trading Company
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:81409-90-7
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquirySuperior quality, moderate price & quick delivery. Appearance:white crystalline solid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:as per your request Application:A dopamine D2-receptor agonist. Transpo
Conditions | Yield |
---|---|
tetrakis(triphenylphosphine) palladium(0) In toluene at 20℃; for 2h; | 92.3% |
cabergoline
Conditions | Yield |
---|---|
In n-heptane at 55℃; Product distribution / selectivity; | 90% |
at 55 - 70℃; under 1.50015 Torr; for 24 - 92h; Product distribution / selectivity; | |
at 60℃; under 750.075 Torr; for 24h; | |
In diethyl ether; n-heptane at -35 - -15℃; for 8h; Product distribution / selectivity; |
cabergoline
Conditions | Yield |
---|---|
for 15h; Product distribution / selectivity; Drying under a blanket of nitrogen; | 86% |
at 40℃; under 65.2565 - 83.2583 Torr; for 16 - 17h; Product distribution / selectivity; | |
at 60℃; for 20.5h; Product distribution / selectivity; | |
at 20 - 25℃; under 525.053 - 675.068 Torr; for 29.25h; Product distribution / selectivity; Vacuum; | |
at 40℃; for 2h; Product distribution / selectivity; Stream of nitrogen; |
(6aR,9R,10aR)-7-allyl-N-[3-(dimethylamino)propyl]-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxamide
ethyl isocyanate
A
cabergoline
B
(6aR,9R,10aR)-7-allyl-N9-[3-(dimethylamino)propyl]-N4-ethyl-N9-(ethylcarbamoyl)-6a,7,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-4,9(6H)-dicarboxamide
Conditions | Yield |
---|---|
In toluene Heating; | A 81% B 0.57 g |
(6aR,9R,10aR)-7-allyl-N-[3-(dimethylamino)propyl]-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxamide
ethyl isocyanate
cabergoline
Conditions | Yield |
---|---|
Stage #1: (6aR,9R,10aR)-7-allyl-N-[3-(dimethylamino)propyl]-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxamide With trimethylsilyl trifluoromethanesulfonate; triethylamine In dichloromethane at -2 - 18℃; for 14h; Stage #2: ethyl isocyanate In dichloromethane at 18℃; for 48h; Stage #3: With tetrabutyl ammonium fluoride In tetrahydrofuran; dichloromethane at -2℃; for 4h; | 68.2% |
1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride
(6aR,9R,10aR)-7-allyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylic acid
A
cabergoline
B
N-<<<3-(dimethylamino)propyl>amino>carbonyl>-N-ethyl-6-(2-propenyl)-ergoline-8β-carboxamide
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 0 - 25℃; for 20h; Product distribution / selectivity; | A 54.7% B n/a |
With triethylamine In N,N-dimethyl-formamide Ambient temperature; | A 46% B 35% |
With triethylamine In ethyl acetate at 20℃; Product distribution / selectivity; |
tert-butyl (5R,8R,10R)-6-allyl-8-[[[3-(dimethylamino)propyl][(ethylamino)carbonyl]amino]carbonyl]ergoline-1-carboxylate
cabergoline
Conditions | Yield |
---|---|
With hydrogenchloride In water at 80℃; for 1h; |
methyl (6aR,9R,10aR)-7-allyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate
cabergoline
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 85 percent / 2-hydroxypyridine / ethane-1,2-diol / 18 h / 100 °C 2: 92 percent / 4-(dimethylamino)pyridine / tetrahydrofuran / 2 h / 40 °C 3: NaHMDS / tetrahydrofuran / -40 - 20 °C 4: propan-2-ol / 18 h / 50 °C 5: aqueous hydrochloric acid / H2O / 1 h / 80 °C View Scheme | |
Multi-step reaction with 2 steps 1: 85 percent / acetic acid / Heating 2: 81 percent / toluene / Heating View Scheme |
(6aR,9R,10aR)-7-allyl-N-[3-(dimethylamino)propyl]-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxamide
cabergoline
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 92 percent / 4-(dimethylamino)pyridine / tetrahydrofuran / 2 h / 40 °C 2: NaHMDS / tetrahydrofuran / -40 - 20 °C 3: propan-2-ol / 18 h / 50 °C 4: aqueous hydrochloric acid / H2O / 1 h / 80 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 85 percent / 2-hydroxypyridine / ethane-1,2-diol / 18 h / 100 °C 2: 92 percent / 4-(dimethylamino)pyridine / tetrahydrofuran / 2 h / 40 °C 3: NaHMDS / tetrahydrofuran / -40 - 20 °C 4: propan-2-ol / 18 h / 50 °C 5: aqueous hydrochloric acid / H2O / 1 h / 80 °C View Scheme |
tert-butyl (5R,8R,10R)-6-allyl-8-[[[3-(dimethylamino)propyl]amino]carbonyl]ergoline-1-carboxylate
cabergoline
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: NaHMDS / tetrahydrofuran / -40 - 20 °C 2: propan-2-ol / 18 h / 50 °C 3: aqueous hydrochloric acid / H2O / 1 h / 80 °C View Scheme |
tert-butyl (5R,8R,10R)-6-allyl-8-[[[3-(dimethylamino)propyl](phenoxycarbonyl)amino]carbonyl]ergoline-1-carboxylate
cabergoline
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: propan-2-ol / 18 h / 50 °C 2: aqueous hydrochloric acid / H2O / 1 h / 80 °C View Scheme |
1-amino-3-(dimethylamino)propane
cabergoline
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 85 percent / acetic acid / Heating 2: 81 percent / toluene / Heating View Scheme |
cabergoline
Conditions | Yield |
---|---|
With ammonium fluoride In tetrahydrofuran; water |
C32H51N5O2Si
cabergoline
Conditions | Yield |
---|---|
With ammonium fluoride In methanol; water at 20℃; for 3h; |
N-(3-dimethylaminopropyl)-N-ethylcarbodiimide
(6aR,9R,10aR)-7-allyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylic acid
cabergoline
Conditions | Yield |
---|---|
Stage #1: N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; (6aR,9R,10aR)-7-allyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylic acid In trifluoromethylbenzene (BTF) at 24 - 38℃; Stage #2: With water; acetic acid In trifluoromethylbenzene (BTF) pH=5.0 - 5.5; Stage #3: With potassium hydroxide In tert-butyl methyl ether; water pH=9.5 - 10.0; |
cabergoline
Conditions | Yield |
---|---|
at 30 - 60℃; under 0.750075 Torr; for 25h; Product distribution / selectivity; |
1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride
(6aR,9R,10aR)-7-allyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylic acid
cabergoline
Conditions | Yield |
---|---|
Stage #1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; (6aR,9R,10aR)-7-allyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylic acid With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 30h; Stage #2: With ammonia; water In dichloromethane |
Conditions | Yield |
---|---|
Stage #1: tert-Amyl methyl ether; cabergoline at 41 - 50℃; for 0.25h; Stage #2: cabergoline at 0 - 27℃; for 16.5h; | 88.8% |
4-(3-Aminopropyl)morpholine
cabergoline
(5R,8R,10R)-6-allyl-N-[3-(morpholino)propyl]ergoline-8-carboxamide
Conditions | Yield |
---|---|
at 65℃; for 144h; Inert atmosphere; Sealed tube; | 80% |
at 65℃; for 144h; Inert atmosphere; Sealed tube; | 80% |
cabergoline
chlorobenzene
Conditions | Yield |
---|---|
In n-heptane at -20 - 20℃; for 1.25h; |
Conditions | Yield |
---|---|
Stage #1: ethylbenzene; cabergoline at -23 - 30℃; for 0.5h; Stage #2: n-heptane at -23 - -17℃; for 3.66667h; |
methanol
cabergoline
methyl (6aR,9R,10aR)-7-allyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate
Conditions | Yield |
---|---|
With triethylamine |
cabergoline
(5R,8R,10R)-6-allyl-N-[3-(morpholino)propyl]-N-[(ethylamino)carbonyl]-ergoline-8-carboxamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: sodium hydroxide / water; methanol 2: triethylamine / dichloromethane View Scheme | |
Multi-step reaction with 3 steps 1: 144 h / 65 °C / Inert atmosphere; Sealed tube 2: dmap / tetrahydrofuran 3: isopropyl alcohol / 50 °C View Scheme |
cabergoline
(6aR,9R,10aR)-7-allyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylic acid
Conditions | Yield |
---|---|
Stage #1: cabergoline With sodium hydroxide In methanol; water Stage #2: With hydrogenchloride In methanol; water |
cabergoline
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 144 h / 65 °C / Inert atmosphere; Sealed tube 2: dmap / tetrahydrofuran View Scheme |
Conditions | Yield |
---|---|
With copper (I) acetate In methanol at 40℃; for 4.5h; Inert atmosphere; |
Conditions | Yield |
---|---|
Stage #1: cabergoline; β‐cyclodextrin In methanol; water at 20℃; for 0.5h; Sonication; Stage #2: In methanol; water at 20 - 50℃; for 48h; |
N-ethyl-L-glutamine
cabergoline
Conditions | Yield |
---|---|
In water; isopropyl alcohol |
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