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Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: Betamethasone 21-acetate Synonyms: 1,4-PREGNADIEN-9-ALPHA-FLUORO-16-BETA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE 21-ACETATE;BETAMETHASONE 21-ACETATE;BETAMETHASONE ACETATE;9-fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-dien

Betamethasone 21-acetate 99% Manufactuered in China best quality

Cas:987-24-6

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Jai Radhe Sales

Betamethasone Acetate

Betamethasone 21-acetate

Cas:987-24-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Betamethasone 21-acetate

Cas:987-24-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

Introduction: Appearance: A white or crystalline powder CAS:987-24-6 Specs: CP2005/USP/BP/EP Molecular formula:C24H31FO6 Commodity: Betamethasone Acetate Appearance: A white or crystalline powder

CAS:987-24-6 Betamethasone 21-acetate factory sales

Cas:987-24-6

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Xi'an Quanao Biotech Co., Ltd.

Xi’an Quanao Biotech Co., Ltd. with 18 years experience in plant extract filed. Product grade: Medicine, Health care product, Cosmetics, Food, Beverage, Feed. Hot selling market: Europe, North America, South America, Middle East, Asia Pacifi

Top purity 99% Betamethasone 21-acetate powder CAS:987-24-6

Cas:987-24-6

Min.Order:100 Gram

FOB Price: $1.19 / 1.39

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Product Name: betamethasone 21-acetate CAS RN.: 987-24-6 EINECS: 213-578-6

Betamethasone 21-acetate 987-24-6

Cas:987-24-6

Min.Order:250 Kilogram

Negotiable

Type:Trading Company

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Betamethasone Acetate

Cas:987-24-6

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Betamethasone 21-acetate 987-24-6 GMP Manufacturer

Cas:987-24-6

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company engages in Sodium Tripolyphosphate (STPP) and Sodium Hexametabphosphate (SHMP) production; development of noble metal catalysts, synthesis of electronic chemical materials and general chemicals Imp&Exp trading business. The company

TIANFU-CHEM -Betamethasone 21-acetate

Cas:987-24-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 987-24-6 with fast shipping

Cas:987-24-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Betamethasone 21-acetate/ LIDE PHARMA- Factory supply / Best price

Cas:987-24-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:White to Off-White powder Storage:Refrigerator Package:25kg/drum Application:amino acid, nutrient Transportation:Express/Sea/Air Port:any port in china

Betamethasone 21-acetate factory price

Cas:987-24-6

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White powder Storage:Store in sealed containers at cool & dr

Betamethasone 21-acetate Natural Prohormones Powder CAS 987-24-6

Cas:987-24-6

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Betamethasone 21-Acetate CAS No.: 987-24-6

Cas:987-24-6

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1,In No Less five years exporting experience. 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Onchem specialized in APIs, chemical intermed

Betamethasone acetate 99%

Cas:987-24-6

Min.Order:1 Kilogram

FOB Price: $10.0

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Betamethasone 21-acetate CAS:987-24-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic in

Betamethasone 21-acetate CAS:987-24-6

Cas:987-24-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Betamethasone Acetate Corticosteroid Raw Powder

Cas:987-24-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Betamethasone Acetate

Cas:987-24-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Betamethasone Acetate

Cas:987-24-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

Betamethasone 21-acetate

Cas:987-24-6

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Betamethasone 21-acetate

Cas:987-24-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

Betamethasone 21-acetate

Cas:987-24-6

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: Betamethasone 21-Acetate CAS No.:987-24-6 Molecule Formula:C24H31FO6 Molecule Weight:434.50 Purity: 99.0% Package: 25kg/drum Description:White or off-white powder Manufacture Standards:Enterprise Standard TESTING IT

High Quality Betamethasone 21-Acetate on stock

Cas:987-24-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Factory SellsBetamethasone 21-acetate

Cas:987-24-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Betamethasone21-acetate

Cas:987-24-6

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Betamethasone 21-acetate Basic information Product Name: Betamethasone 21-acetate Synonyms: 9alpha-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 21-acetate;(11β,16β)-21-(Acetyloxy)-9-fluoro-11,17-dihydroxy-1

Betamethasone 21-acetate

Cas:987-24-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

Betamethasone acetate

Cas:987-24-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

Betamethasone 21-acetate

Cas:987-24-6

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Betamethasone acetate

Cas:987-24-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

Betamethasone acetate

Cas:987-24-6

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Synthetic route

21-acetoxy-9,11β-epoxy-17-hydroxy-16β-methyl-9β-pregna-1,4-diene-3,20-dione
912-38-9, 2884-51-7, 14622-51-6, 98573-86-5

21-acetoxy-9,11β-epoxy-17-hydroxy-16β-methyl-9β-pregna-1,4-diene-3,20-dione

betamethasone 21-acetate
987-24-6

betamethasone 21-acetate

Conditions
ConditionsYield
With tetrahydrofuran; chloroform; hydrogen fluoride
9β,11β-epoxy-17α,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-acetate

9β,11β-epoxy-17α,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 21-acetate

betamethasone 21-acetate
987-24-6

betamethasone 21-acetate

Conditions
ConditionsYield
With hydrogen fluoride In chloroform
(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2,2-Diiodo-acetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-cyclopenta[a]phenanthren-3-one
37414-01-0

(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2,2-Diiodo-acetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-cyclopenta[a]phenanthren-3-one

potassium acetate
127-08-2

potassium acetate

betamethasone 21-acetate
987-24-6

betamethasone 21-acetate

Conditions
ConditionsYield
With acetic acid In water; acetone for 3h; Heating;180 mg
16α,17α-epoxy-3β-hydroxy-5α-pregn-9(11)-en-20-one
884488-47-5

16α,17α-epoxy-3β-hydroxy-5α-pregn-9(11)-en-20-one

betamethasone 21-acetate
987-24-6

betamethasone 21-acetate

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1.1: 95 percent / pyridine / 20 °C
2.1: 70 percent / triethyl orthoformate; p-toluenesulfonic acid / CH2Cl2 / 20 h / 20 °C
3.1: 72 percent / tetrahydrofuran; diethyl ether / 72 h / 60 °C
4.1: m-iodoxybenzoic acid; diphenyl diselenide / toluene / 22 h / Heating
4.2: 50 percent / p-toluenesulfonic acid / CH2Cl2 / 4 h / 20 °C
5.1: perchloric acid; 1,3-dibromo-5,5-dimethylhydantoin / dimethylformamide / 3 h / cooling
5.2: 75.8 percent / sodium hydroxide / CH2Cl2; methanol; H2O / 2 h / cooling
6.1: 80 percent / hydrofluoric acid / tetrahydrofuran; CH2Cl2 / 5 h / -70 - 0 °C
7.1: 100 percent / anhydrous calcium chloride; calcium oxide; iodine / methanol / 1 h / 25 - 27 °C
8.1: 180 mg / acetic acid / acetone; H2O / 3 h / Heating
View Scheme
16β-methyl-9β,11β-epoxy-17α-hydroxy-1,4-pregnadiene-3,20-dione
37413-99-3

16β-methyl-9β,11β-epoxy-17α-hydroxy-1,4-pregnadiene-3,20-dione

betamethasone 21-acetate
987-24-6

betamethasone 21-acetate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 80 percent / hydrofluoric acid / tetrahydrofuran; CH2Cl2 / 5 h / -70 - 0 °C
2: 100 percent / anhydrous calcium chloride; calcium oxide; iodine / methanol / 1 h / 25 - 27 °C
3: 180 mg / acetic acid / acetone; H2O / 3 h / Heating
View Scheme
hecogenin acetate
915-35-5

hecogenin acetate

betamethasone 21-acetate
987-24-6

betamethasone 21-acetate

Conditions
ConditionsYield
Multi-step reaction with 12 steps
1.1: 72 percent / m-iodoxybenzoic acid; diphenyl diselenide / toluene / 12 h / Heating
2.1: hydrazine hydrate / ethane-1,2-diol / 1 h / Heating
2.2: 95 percent / potassium hydroxide / ethane-1,2-diol; H2O / 5 h / 195 - 197 °C
3.1: pyridine; ammonium chloride / 125 - 135 °C
3.2: acetic acid; chromium trioxide / H2O; 1,2-dichloro-ethane / 1 h / 20 °C
3.3: 57 percent / aluminium oxide / benzene / 2 h
4.1: 91.7 percent / hydrogen peroxide; sodium hydroxide / methanol / 2 h / 20 °C
5.1: 95 percent / pyridine / 20 °C
6.1: 70 percent / triethyl orthoformate; p-toluenesulfonic acid / CH2Cl2 / 20 h / 20 °C
7.1: 72 percent / tetrahydrofuran; diethyl ether / 72 h / 60 °C
8.1: m-iodoxybenzoic acid; diphenyl diselenide / toluene / 22 h / Heating
8.2: 50 percent / p-toluenesulfonic acid / CH2Cl2 / 4 h / 20 °C
9.1: perchloric acid; 1,3-dibromo-5,5-dimethylhydantoin / dimethylformamide / 3 h / cooling
9.2: 75.8 percent / sodium hydroxide / CH2Cl2; methanol; H2O / 2 h / cooling
10.1: 80 percent / hydrofluoric acid / tetrahydrofuran; CH2Cl2 / 5 h / -70 - 0 °C
11.1: 100 percent / anhydrous calcium chloride; calcium oxide; iodine / methanol / 1 h / 25 - 27 °C
12.1: 180 mg / acetic acid / acetone; H2O / 3 h / Heating
View Scheme
17α,21-dihydroxy-16β-methyl-1,4,9(11)-pregnatriene-3,20-dione 21-acetate
910-99-6

17α,21-dihydroxy-16β-methyl-1,4,9(11)-pregnatriene-3,20-dione 21-acetate

betamethasone 21-acetate
987-24-6

betamethasone 21-acetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hypobromous acid; sodium acetate
2: CHCl3; THF; HF
View Scheme
betamethasone
378-44-9

betamethasone

acetic anhydride
108-24-7

acetic anhydride

betamethasone 21-acetate
987-24-6

betamethasone 21-acetate

Conditions
ConditionsYield
With sodium acetate In tetrahydrofuran; acetone at 40℃; for 3h; Inert atmosphere;
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

betamethasone 21-acetate
987-24-6

betamethasone 21-acetate

(11β,16β)-9-fluoro-16-methyl-3,20-dioxo-11,17-bis[(trimethylsilyl)oxy]pregna-1,4-dien-21-yl acetate
733766-12-6

(11β,16β)-9-fluoro-16-methyl-3,20-dioxo-11,17-bis[(trimethylsilyl)oxy]pregna-1,4-dien-21-yl acetate

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 16h;99%
betamethasone 21-acetate
987-24-6

betamethasone 21-acetate

betamethasone
378-44-9

betamethasone

Conditions
ConditionsYield
With methanol; sodium methylate at 25℃; for 4h;90%
betamethasone 21-acetate
987-24-6

betamethasone 21-acetate

benzoyl chloride
98-88-4

benzoyl chloride

9α-fluoro-3,11β,17α,21-tetrahydroxy-16β-methyl-1,3,5-pregnatriene-20-one 21-acetate 3-benzoate
59860-91-2

9α-fluoro-3,11β,17α,21-tetrahydroxy-16β-methyl-1,3,5-pregnatriene-20-one 21-acetate 3-benzoate

Conditions
ConditionsYield
In pyridine at 70℃; for 18h;71%
betamethasone 21-acetate
987-24-6

betamethasone 21-acetate

9α-fluoro-6β,11β,17α,21-tetrahydroxy-16β-methyl-1,4-pregnadiene-3,20-dione 21-acetate
72559-76-3

9α-fluoro-6β,11β,17α,21-tetrahydroxy-16β-methyl-1,4-pregnadiene-3,20-dione 21-acetate

Conditions
ConditionsYield
With selenium(IV) oxide In 1,4-dioxane at 80℃; for 2.5h;22%
Multi-step reaction with 2 steps
1: 71 percent / pyridine / 18 h / 70 °C
2: 58 percent / m-chloroperbenzoic acid / CHCl3 / 1 h / Ambient temperature
View Scheme
betamethasone 21-acetate
987-24-6

betamethasone 21-acetate

9α-fluoro-11β,17α,21-trihydroxy-16β-methyl-1,4-pregnadiene-3,6,20-trione
72559-90-1

9α-fluoro-11β,17α,21-trihydroxy-16β-methyl-1,4-pregnadiene-3,6,20-trione

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 71 percent / pyridine / 18 h / 70 °C
2: 58 percent / m-chloroperbenzoic acid / CHCl3 / 1 h / Ambient temperature
3: 61 percent / pyridine/ CF3-COOH/ 1-cyclohexyl-3-(2-morpholinoethyl) carbodiimide metho-p-toluenesulfonate / dimethylsulfoxide; benzene / 16 h / Ambient temperature
4: 75 percent / Na2CO3 / methanol / 18 h / Ambient temperature
View Scheme
betamethasone 21-acetate
987-24-6

betamethasone 21-acetate

9α-fluoro-11β,17α,21-trihydroxy-16β-methyl-1,4-pregnadiene-3,6,20-trione 17-propionate
72560-06-6

9α-fluoro-11β,17α,21-trihydroxy-16β-methyl-1,4-pregnadiene-3,6,20-trione 17-propionate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 71 percent / pyridine / 18 h / 70 °C
2: 58 percent / m-chloroperbenzoic acid / CHCl3 / 1 h / Ambient temperature
3: 61 percent / pyridine/ CF3-COOH/ 1-cyclohexyl-3-(2-morpholinoethyl) carbodiimide metho-p-toluenesulfonate / dimethylsulfoxide; benzene / 16 h / Ambient temperature
4: 75 percent / Na2CO3 / methanol / 18 h / Ambient temperature
5: 73 percent / 1.) p-toluenesulfonic acid monohydrate; 2.) 90percent CH3COOH aq. / Ambient temperature; 1.) DMSO, 4 h; 2.) 4 h
View Scheme
betamethasone 21-acetate
987-24-6

betamethasone 21-acetate

9α-fluoro-11β,17α,21-trihydroxy-16β-methyl-1,4-pregnadiene-3,6,20-trione 17-isobutyrate
72559-92-3

9α-fluoro-11β,17α,21-trihydroxy-16β-methyl-1,4-pregnadiene-3,6,20-trione 17-isobutyrate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 71 percent / pyridine / 18 h / 70 °C
2: 58 percent / m-chloroperbenzoic acid / CHCl3 / 1 h / Ambient temperature
3: 61 percent / pyridine/ CF3-COOH/ 1-cyclohexyl-3-(2-morpholinoethyl) carbodiimide metho-p-toluenesulfonate / dimethylsulfoxide; benzene / 16 h / Ambient temperature
4: 75 percent / Na2CO3 / methanol / 18 h / Ambient temperature
5: 79 percent / 1.) p-toluenesulfonic acid monohydrate; 2.) 90percent CH3COOH aq. / Ambient temperature; 1.) DMSO, 4 h; 2.) 4 h
View Scheme
betamethasone 21-acetate
987-24-6

betamethasone 21-acetate

9α-fluoro-11β,17α,21-trihydroxy-16β-methyl-1,4-pregnadiene-3,6,20-trione 21-acetate
72559-84-3

9α-fluoro-11β,17α,21-trihydroxy-16β-methyl-1,4-pregnadiene-3,6,20-trione 21-acetate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 71 percent / pyridine / 18 h / 70 °C
2: 58 percent / m-chloroperbenzoic acid / CHCl3 / 1 h / Ambient temperature
3: 61 percent / pyridine/ CF3-COOH/ 1-cyclohexyl-3-(2-morpholinoethyl) carbodiimide metho-p-toluenesulfonate / dimethylsulfoxide; benzene / 16 h / Ambient temperature
View Scheme
betamethasone 21-acetate
987-24-6

betamethasone 21-acetate

9α-fluoro-11β,17α,21-trihydroxy-16β-methyl-1,4-pregnadiene-3,6,20-trione 17-butyrate
82926-63-4

9α-fluoro-11β,17α,21-trihydroxy-16β-methyl-1,4-pregnadiene-3,6,20-trione 17-butyrate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 71 percent / pyridine / 18 h / 70 °C
2: 58 percent / m-chloroperbenzoic acid / CHCl3 / 1 h / Ambient temperature
3: 61 percent / pyridine/ CF3-COOH/ 1-cyclohexyl-3-(2-morpholinoethyl) carbodiimide metho-p-toluenesulfonate / dimethylsulfoxide; benzene / 16 h / Ambient temperature
4: 75 percent / Na2CO3 / methanol / 18 h / Ambient temperature
5: 44 percent / 1.) p-toluenesulfonic acid monohydrate; 2.) 90percent CH3COOH aq. / Ambient temperature; 1.) DMSO, 4 h; 2.) 4 h
View Scheme
betamethasone 21-acetate
987-24-6

betamethasone 21-acetate

9α-fluoro-11β,17α,21-trihydroxy-16β-methyl-1,4-pregnadiene-3,6,20-trione 17-valerate
72560-03-3

9α-fluoro-11β,17α,21-trihydroxy-16β-methyl-1,4-pregnadiene-3,6,20-trione 17-valerate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 71 percent / pyridine / 18 h / 70 °C
2: 58 percent / m-chloroperbenzoic acid / CHCl3 / 1 h / Ambient temperature
3: 61 percent / pyridine/ CF3-COOH/ 1-cyclohexyl-3-(2-morpholinoethyl) carbodiimide metho-p-toluenesulfonate / dimethylsulfoxide; benzene / 16 h / Ambient temperature
4: 75 percent / Na2CO3 / methanol / 18 h / Ambient temperature
5: 41 percent / 1.) p-toluenesulfonic acid monohydrate; 2.) 90percent CH3COOH aq. / Ambient temperature; 1.) DMSO, 4 h; 2.) 4 h
View Scheme
betamethasone 21-acetate
987-24-6

betamethasone 21-acetate

9α-fluoro-11β,17α,21-trihydroxy-16β-methyl-1,4-pregnadiene-3,6,20-trione 21-trimethylacetate
72559-93-4

9α-fluoro-11β,17α,21-trihydroxy-16β-methyl-1,4-pregnadiene-3,6,20-trione 21-trimethylacetate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 71 percent / pyridine / 18 h / 70 °C
2: 58 percent / m-chloroperbenzoic acid / CHCl3 / 1 h / Ambient temperature
3: 61 percent / pyridine/ CF3-COOH/ 1-cyclohexyl-3-(2-morpholinoethyl) carbodiimide metho-p-toluenesulfonate / dimethylsulfoxide; benzene / 16 h / Ambient temperature
4: 75 percent / Na2CO3 / methanol / 18 h / Ambient temperature
5: 64 percent / pyridine / 72 h / Ambient temperature
View Scheme
betamethasone 21-acetate
987-24-6

betamethasone 21-acetate

9α-fluoro-11β,17α,21-trihydroxy-16β-methyl-1,4-pregnadiene-3,6,20-trione 17-benzoate
72560-07-7

9α-fluoro-11β,17α,21-trihydroxy-16β-methyl-1,4-pregnadiene-3,6,20-trione 17-benzoate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 71 percent / pyridine / 18 h / 70 °C
2: 58 percent / m-chloroperbenzoic acid / CHCl3 / 1 h / Ambient temperature
3: 61 percent / pyridine/ CF3-COOH/ 1-cyclohexyl-3-(2-morpholinoethyl) carbodiimide metho-p-toluenesulfonate / dimethylsulfoxide; benzene / 16 h / Ambient temperature
4: 75 percent / Na2CO3 / methanol / 18 h / Ambient temperature
5: 29 percent / 1.) p-toluenesulfonic acid monohydrate; 2.) 90percent CH3COOH aq. / Ambient temperature; 1.) 120 h; 2.) 4 h
View Scheme
betamethasone 21-acetate
987-24-6

betamethasone 21-acetate

9α-fluoro-6,11β,17α,21-tetrahydroxy-16β-methyl-1,4,6-pregnatriene-3,20-dione 6,17,21-tripropionate
72559-33-2

9α-fluoro-6,11β,17α,21-tetrahydroxy-16β-methyl-1,4,6-pregnatriene-3,20-dione 6,17,21-tripropionate

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 71 percent / pyridine / 18 h / 70 °C
2: 58 percent / m-chloroperbenzoic acid / CHCl3 / 1 h / Ambient temperature
3: 61 percent / pyridine/ CF3-COOH/ 1-cyclohexyl-3-(2-morpholinoethyl) carbodiimide metho-p-toluenesulfonate / dimethylsulfoxide; benzene / 16 h / Ambient temperature
4: 75 percent / Na2CO3 / methanol / 18 h / Ambient temperature
5: 73 percent / 1.) p-toluenesulfonic acid monohydrate; 2.) 90percent CH3COOH aq. / Ambient temperature; 1.) DMSO, 4 h; 2.) 4 h
6: 90 percent / pyridine / 5 h / Ambient temperature
View Scheme

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