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Jinzhou Jiutai Pharmaceutical Co.,Ltd

Country:China (Mainland)

Year Established: 1951Business type: Manufacturers

Integral:

1. Betahistine dihydrochloride specification
Appearance: White to almost crystalline powder, very hygroscopic
Assay: 99.75%
Ph: 2.5
Loss on drying: 0.3%
Sulphated ash: 0.06%
IR: Similar to the reference standard
HPLC: Similar to the reference standard
Residual solvents: 0.20%
Solubility: Freely soluble in alcohol (96%)
The information of betahistine dihydrochloride specification above is for reference.



2. Pure betahistine dihydrochloride
Pure betahistine dihydrochloride progressively enhances cAMP formation with a maximal effect, observed up to 10 nM, in CHO(H3R) cells incubated with 3 μM forskolin. In contrast, at concentrations higher than 10 nM betahistine progressively inhibits cAMP formation in CHO(H3R) cells incubated with 3 μM forskolin. What's more, pure betahistine dihydrochloride
(16 mg tid and 48 mg tid) shows that the number of attacks per month decreased in both doses over time in Menière's disease. Betahistine (50 mg/kg) treatment induces symmetrical changes with up-regulation of histidine decarboxylase mRNA in the tuberomammillary nucleus and reduction of [3H]N-alpha-methylhistamine labeling in both the tuberomammillary nucleus, the vestibular nuclei complex and nuclei of the inferior olive in brain sections of cats.

Other products from this supplier

High purity betahistine dihydrochloride

High purity betahistine dihydrochloride is a medicine which is used in Mnire's syndrome. High purity betahistine dihydrochloride is also called as 2-Pyridineethanamine,N-methyl-, dihydrochloride (9CI).

High- Quality omeprazole sodium

High- Quality omeprazole sodium has wide usage in heath as follows. Among all of the factories, Jinzhou Jiutai Pharmaceutical Co.,Ltd is one of omeprazole sodium good supplier in China.

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