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HANGZHOU HOLYPHARM BIOTECH CO.,LTD

Country:China (Mainland)

Year Established: 2009Business type: Other

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1. Azilsartan basic information

Azilsartan
(codename TAK-536) has its CAS registry number of 147403-03-0 and its IUPAC name of Azilsartan is 2-ethoxy-3-[[4-[2-(5-oxo-2H-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid. With the molecular formula of C25H20N4O5 and molecular weight of 456.45, it is the angiotensin type 1 receptor blocker; receptor blocker.

2. Chemical and physical properties of Azilsartan                                                    azilsarton chemical structure

1). MonoIsotopic Mass: 456.14337;
2). Topological Polar Surface Area: 115;
3). Heavy Atom Count: 34;
4). Complexity: 783;
5). Density: 1.42 cm3.

3. Azilsartan Pharmacological effects and Azilsartan usage

As to the Azilsartan usage, it could be applied as one angiotensin II receptor antagonist when treat hypertension which is caused from Takeda. When comes to the Azilsartan market, this chemical is marketed with the form of one prodrug azilsartan medoxomil called TAK-491, which is approved by FDA for the treatment of high blood pressure in 2011.

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