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HANGZHOU HOLYPHARM BIOTECH CO.,LTD

Country:China (Mainland)

Year Established: 2009Business type: Other

Integral:

1. What is Bepotastine?
Bepotastine (CAS NO.125602-71-3)
is a white product and has chemical name that is 4-[4-[(4-Chlorophenyl)pyridin-2-ylmethoxy]piperidin-1-yl]butanoic acid. And the molecular formula of this chemical is C21H25ClN2O3. The Molecular Weight of it is 388.89. Bepotastine is an antihistamine, and was approved in Japan for use in the treatment of allergic rhinitis and uriticaria/puritus.

2. Other properties of Bepotastine
Bepotastine structure
:



Other Bepotastine properties:
(1)ACD/LogP: 3.011 ; (2)# of Rule of 5 Violations: 0 ; (3)ACD/LogD (pH 5.5): 0.48 ; (4)ACD/LogD (pH 7.4): 0.51 ; (5)ACD/BCF (pH 5.5): 1.00 ; (6)ACD/BCF (pH 7.4): 1.00 ; (7)ACD/KOC (pH 5.5): 3.03 ; (8)ACD/KOC (pH 7.4): 3.27 ; (9)#H bond acceptors: 5 ; (10)#H bond donors: 1 ; (11)#Freely Rotating Bonds: 8 ; (12)Polar Surface Area: 62.66 Å2 ; (13)Index of Refraction: 1.605 ; (14)Molar Refractivity: 105.584 cm3 ; (15)Molar Volume: 306.552 cm3 ; (16)Polarizability: 41.857 10-24cm3 ; (17)Surface Tension: 58.0429992675781 dyne/cm ; (18)Density: 1.269 g/cm3 ; (19)Flash Point: 284.506 °C ; (20)Enthalpy of Vaporization: 86.926 kJ/mol ; (21)Boiling Point: 546.819 °C at 760 mmHg ; (22)Vapour Pressure: 0 mmHg at 25°C.

3. Bepotastine (DB04890) and Bepotastine (Bepreve)
Bepotastine (DB04890) and Bepotastine (Bepreve)
are the finished drug products of bepotastine and bepotastine besilate. Bepotastine (DB04890) is an antihistamine. And the Bepotastine (Bepreve) is a prescription antihistamine eye drop that relieves itching (commonly called "itchy eyes") associated with allergic conjunctivitis.

4. Bepotastine Suppliers
Bepotastine
as an antihistamine has its suppliers and manufacturers all around the world. In China, there are some suppliers of bepotastine such as HANGZHOU HOLYPHARM BIOTECH CO.,LTD a professional supplier of active pharmaceutical ingredients and intermediates. Some bepotastine Suppliers are the supplier of bepotastine raw material. And they all have the export capability. Hence, when you are seeking for cooperation, please come to China.

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