Product Name

  • Name

    beta-hydroxyethoxyacetic acid

  • EINECS
  • CAS No. 13382-47-3
  • Article Data7
  • CAS DataBase
  • Density 1.291 g/cm3
  • Solubility
  • Melting Point 44 °C
  • Formula C4H8O4
  • Boiling Point 323.75 °C at 760 mmHg
  • Molecular Weight 120.105
  • Flash Point 147.314 °C
  • Transport Information
  • Appearance
  • Safety
  • Risk Codes
  • Molecular Structure Molecular Structure of 13382-47-3 (beta-hydroxyethoxyacetic acid)
  • Hazard Symbols
  • Synonyms Aceticacid, (2-hydroxyethoxy)- (7CI,8CI,9CI);Acetic acid,2-(2-hydroxyethoxy)-;b-Hydroxyethoxyacetic acid;
  • PSA 66.76000
  • LogP -0.92010

Synthetic route

1,4-dioxane
123-91-1

1,4-dioxane

2-(2-hydroxyethoxy)acetic acid
13382-47-3

2-(2-hydroxyethoxy)acetic acid

Conditions
ConditionsYield
With α-chlorooxohexamethylenimine; silver carbonate at 100℃;
With hydrogenchloride; sodium hypochlorite
diethylene glycol
111-46-6

diethylene glycol

2-(2-hydroxyethoxy)acetic acid
13382-47-3

2-(2-hydroxyethoxy)acetic acid

Conditions
ConditionsYield
With hydrogenchloride; sodium hypochlorite
With F101S-Phanerochaete chrysosporium In aq. phosphate buffer at 35℃; for 48h; pH=7.5; Enzymatic reaction;> 99 %Spectr.
sodium monochloroacetic acid
3926-62-3

sodium monochloroacetic acid

ethylene glycol
107-21-1

ethylene glycol

2-(2-hydroxyethoxy)acetic acid
13382-47-3

2-(2-hydroxyethoxy)acetic acid

Conditions
ConditionsYield
Stage #1: ethylene glycol With sodium
Stage #2: sodium monochloroacetic acid at 100℃; for 10h;
Stage #1: ethylene glycol With sodium
Stage #2: sodium monochloroacetic acid Further stages.;
2-(2-methoxyethoxy)acetic acid
16024-56-9

2-(2-methoxyethoxy)acetic acid

2-(2-hydroxyethoxy)acetic acid
13382-47-3

2-(2-hydroxyethoxy)acetic acid

Conditions
ConditionsYield
With hydrogen bromide at 20 - 150℃; for 8h;
ethylene glycol
107-21-1

ethylene glycol

bromoacetic acid
79-08-3

bromoacetic acid

2-(2-hydroxyethoxy)acetic acid
13382-47-3

2-(2-hydroxyethoxy)acetic acid

Conditions
ConditionsYield
Stage #1: ethylene glycol With sodium at 20 - 100℃; Inert atmosphere;
Stage #2: bromoacetic acid at 100℃; for 48h;
2-(2-hydroxyethoxy)acetic acid
13382-47-3

2-(2-hydroxyethoxy)acetic acid

4,4'-dimethoxytrityl chloride
40615-36-9

4,4'-dimethoxytrityl chloride

triethylammonium 2-[2-(4,4'-dimethoxytrityloxy)ethoxy] acetate
403730-25-6

triethylammonium 2-[2-(4,4'-dimethoxytrityloxy)ethoxy] acetate

Conditions
ConditionsYield
Stage #1: 2-(2-hydroxyethoxy)acetic acid; 4,4'-dimethoxytrityl chloride In pyridine at 20℃;
Stage #2: With triethylammonium acetate In methanol; dichloromethane; water		100%
propan-1-ol
71-23-8

propan-1-ol

2-(2-hydroxyethoxy)acetic acid
13382-47-3

2-(2-hydroxyethoxy)acetic acid

propyl 5-hydroxy-3-oxapentanoate
872409-89-7

propyl 5-hydroxy-3-oxapentanoate

Conditions
ConditionsYield
With sulfuric acid for 10h; Heating;
methanol
67-56-1

methanol

2-(2-hydroxyethoxy)acetic acid
13382-47-3

2-(2-hydroxyethoxy)acetic acid

methyl 2-(2-hydroxyethoxy)acetate
58349-37-4

methyl 2-(2-hydroxyethoxy)acetate

Conditions
ConditionsYield
With sulfuric acid Heating;
With sulfuric acid for 12h; Reflux;1.22 g
2-(2-hydroxyethoxy)acetic acid
13382-47-3

2-(2-hydroxyethoxy)acetic acid

p-dioxanone
3041-16-5

p-dioxanone

Conditions
ConditionsYield
With hydrogen bromide; sodium hydrogencarbonate at 20℃; pH=3;104 g
2-(2-hydroxyethoxy)acetic acid
13382-47-3

2-(2-hydroxyethoxy)acetic acid

2,6-diisopropylphenol
2078-54-8

2,6-diisopropylphenol

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

propofol (2-methanesulfonate ethoxy)acetate

propofol (2-methanesulfonate ethoxy)acetate

Conditions
ConditionsYield
Stage #1: 2-(2-hydroxyethoxy)acetic acid; methanesulfonyl chloride With pyridine In dichloromethane at 20℃; for 2h;
Stage #2: 2,6-diisopropylphenol With dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 2h;		1.3 g
...Expand
2-(2-hydroxyethoxy)acetic acid
13382-47-3

2-(2-hydroxyethoxy)acetic acid

biotin
58-85-5

biotin

C14H22N2O6S

C14H22N2O6S

Conditions
ConditionsYield
Stage #1: biotin With dmap; dicyclohexyl-carbodiimide In dimethyl sulfoxide at 0℃; for 4h;
Stage #2: 2-(2-hydroxyethoxy)acetic acid In dimethyl sulfoxide at 25℃; for 24h; Darkness;

(2-Hydroxyethoxy)acetic acid Specification

(2-Hydroxyethoxy)acetic acid is an organic compound with the formula C4H8O4, and its systematic name is the same with the product name. With the CAS registry number 13382-47-3, it is also named as beta-Hydroxyethoxyacetic acid. In addition, the molecular weight is 120.10.

Physical properties of (2-Hydroxyethoxy)acetic acid are: (1)ACD/LogP: -1.509; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -3.62; (4)ACD/LogD (pH 7.4): -5.07; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 1.00; (8)ACD/KOC (pH 7.4): 1.00; (9)#H bond acceptors: 4; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 5; (12)Polar Surface Area: 66.76 Å2; (13)Index of Refraction: 1.459; (14)Molar Refractivity: 25.425 cm3; (15)Molar Volume: 93.057 cm3; (16)Polarizability: 10.079×10-24cm3; (17)Surface Tension: 51.67 dyne/cm; (18)Density: 1.291 g/cm3; (19)Flash Point: 147.314 °C; (20)Enthalpy of Vaporization: 65.568 kJ/mol; (21)Boiling Point: 323.75 °C at 760 mmHg; (22)Vapour Pressure: 0 mmHg at 25°C.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(O)COCCO
(2)Std. InChI: InChI=1S/C4H8O4/c5-1-2-8-3-4(6)7/h5H,1-3H2,(H,6,7)
(3)Std. InChIKey: VDNMIIDPBBCMTM-UHFFFAOYSA-N 

Related Products

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View