(3Z)-Dodec-3-en-1-ol supplier

Name
(Z)-dodec-3-en-1-ol
EINECS 251-057-5
CAS No. 32451-95-9
Article Data18
CAS DataBase
Density 0.846 g/cm³
Solubility
Melting Point
Formula C₁₂H₂₄O
Boiling Point 268.1 °C at 760 mmHg
Molecular Weight 184.322
Flash Point 97.6 °C
Transport Information
Appearance
Safety
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms 3-Dodecen-1-ol,(Z)- (8CI);(Z)-3-Dodecen-1-ol;cis-3-Dodecen-1-ol;
PSA 20.23000
LogP 3.67560

Synthetic route

: 55182-73-5
dodec-3-yn-1-ol

: 32451-95-9
(Z)-Dodec-3-en-1-ol

Conditions

Conditions	Yield
With hydrogen; P-2 Ni In ethanol	100%
With hydrogen	96%
With quinoline; hydrogen; Lindlar's catalyst In hexane Ambient temperature;	96%

: 88841-48-9
2-[((Z)-Dodec-3-enyl)oxy]-tetrahydro-pyran

: 32451-95-9
(Z)-Dodec-3-en-1-ol

Conditions

Conditions	Yield
With dowex In methanol at 45℃;	89%
With toluene-4-sulfonic acid In methanol at 20℃; for 16h;	0.28 g

: 79837-93-7
(Z)-3-Dodecensaeure-ethylester

: 32451-95-9
(Z)-Dodec-3-en-1-ol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In diethyl ether	73%

: 1-benzyloxy-4-fluoro-3-dodecene

A: (E)-4-fluoro-dodec-3-en-1-ol

B: (Z)-4-fluoro-dodec-3-en-1-ol

C: 32451-95-9
(Z)-Dodec-3-en-1-ol

D: 68900-87-8
(E)-3-dodecene-1-ol

Conditions

Conditions	Yield
With ammonia; lithium In ethanol at -78℃; Title compound not separated from byproducts.;

...Expand

: 764-93-2
1-decyne

: 32451-95-9
(Z)-Dodec-3-en-1-ol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 1.) BuLi / 1.) HMPA, hexane, a) RT, 15 min, b) 50 deg C, 0.5 h, 2.) HMPA, hexane, a) RT, 1.5 h, b) 50 deg C, 2 h 2: 91 percent / H2, quinoline / Lindlar catalyst / hexane / 1 h / 10 °C View Scheme
Multi-step reaction with 4 steps 1: 1.) n-BuLi, 2.) HMPA / 1.) THF, -20 deg C, 0.5 h, 2.) THF, -78 deg C, 3 h 2: 84 percent / 2 N HCl / acetone / 6 h 3: 86 percent / NaBH4 4: 100 percent / H2 / P-2 Ni / ethanol View Scheme
Multi-step reaction with 2 steps 1: 1.) n-BuLi / 1.) THF/HMPA 2: H2 / Lindlar cat. / hexane View Scheme

: 111-83-1
1-bromo-octane

sodium-compound of decylmalonic acid diethyl ester: sodium-compound of decylmalonic acid diethyl ester

: 32451-95-9
(Z)-Dodec-3-en-1-ol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 1.) LiNH2, NH3 / 1.) THF, 45 min, 2.) THF, 5 h 2: 96 percent / H2, quinoline / 5percent Pd/CaCO3 / hexane / Ambient temperature View Scheme

: 112-31-2
caprinaldehyde

: 32451-95-9
(Z)-Dodec-3-en-1-ol

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1: 63 percent / piperidine / xylene / Heating 2: 83 percent / LAH / diethyl ether 3: Br2 / CCl4 4: NaNH2 / CCl4; aq. NH3 / 4 h / -78 °C 5: 100 percent / H2 / P-2 Ni / ethanol View Scheme
Multi-step reaction with 3 steps 1: tetrahydrofuran / 0 - 20 °C 2: hydrogenchloride / benzene 3: 4,4'-di-tert-butylbiphenyl; lithium / tetrahydrofuran / 0 - 20 °C View Scheme

: 4998-72-5
(E)-dodec-3-enoic acid

: 32451-95-9
(Z)-Dodec-3-en-1-ol

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 83 percent / LAH / diethyl ether 2: Br2 / CCl4 3: NaNH2 / CCl4; aq. NH3 / 4 h / -78 °C 4: 100 percent / H2 / P-2 Ni / ethanol View Scheme

: 68900-87-8
(E)-3-dodecene-1-ol

: 32451-95-9
(Z)-Dodec-3-en-1-ol

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: Br2 / CCl4 2: NaNH2 / CCl4; aq. NH3 / 4 h / -78 °C 3: 100 percent / H2 / P-2 Ni / ethanol View Scheme

: 3,4-Dibromo-dodecan-1-ol

: 32451-95-9
(Z)-Dodec-3-en-1-ol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: NaNH2 / CCl4; aq. NH3 / 4 h / -78 °C 2: 100 percent / H2 / P-2 Ni / ethanol View Scheme

: 148149-64-8
Dodec-3-ynal

: 32451-95-9
(Z)-Dodec-3-en-1-ol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 86 percent / NaBH4 2: 100 percent / H2 / P-2 Ni / ethanol View Scheme

: 148149-63-7
1,1-diethoxy-3-dodecyne

: 32451-95-9
(Z)-Dodec-3-en-1-ol

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 84 percent / 2 N HCl / acetone / 6 h 2: 86 percent / NaBH4 3: 100 percent / H2 / P-2 Ni / ethanol View Scheme

: 124-19-6
nonan-1-al

(+-)-chloroacetic acid-<2-ethyl-hexyl ester>: (+-)-chloroacetic acid-<2-ethyl-hexyl ester>

: 32451-95-9
(Z)-Dodec-3-en-1-ol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 32 percent / 24 h / Heating 2: 73 percent / LiAlH4 / diethyl ether View Scheme

: 111-83-1
1-bromo-octane

: 32451-95-9
(Z)-Dodec-3-en-1-ol

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 1) n-butyllithium / 1) THF, -78 deg C, 2) HMPA, room temperature 2: 91 percent / H2, quinoline / Pd/BaSO4 / methanol 3: 89 percent / Dowex / methanol / 45 °C View Scheme
Multi-step reaction with 2 steps 1: 1.) LiNH2 / 1.) NH3 2.) ether 2: Hydrogen / Pd-BaSO4, quinoline / ethyl acetate View Scheme
Multi-step reaction with 3 steps 1: 1.) n-butyllithium, 2.) LiI / 1.) THF, from -78 deg C to 0 deg C, 2.) a.) DMEU, -78 deg C, b.) 20 deg C, 20 h 2: 72 percent / amberlyst 15 (1+) form> / methanol / 20 h / 40 °C 3: 96 percent / H2 View Scheme
Multi-step reaction with 3 steps 1.1: n-butyllithium / hexane; tetrahydrofuran / 1 h / -78 - 20 °C / Inert atmosphere 1.2: 16 h / Inert atmosphere; Reflux 2.1: potassium hydroxide; N,N-dimethyl-formamide / 6 h / 145 °C / Inert atmosphere; Sealed tube 3.1: toluene-4-sulfonic acid / methanol / 16 h / 20 °C View Scheme

: 87641-52-9
1-<(2-Tetrahydropyranyl)oxy>dodec-3-yne

: 32451-95-9
(Z)-Dodec-3-en-1-ol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 91 percent / H2, quinoline / Pd/BaSO4 / methanol 2: 89 percent / Dowex / methanol / 45 °C View Scheme
Multi-step reaction with 2 steps 1: 72 percent / amberlyst 15 (1+) form> / methanol / 20 h / 40 °C 2: 96 percent / H2 View Scheme
Multi-step reaction with 2 steps 1: potassium hydroxide; N,N-dimethyl-formamide / 6 h / 145 °C / Inert atmosphere; Sealed tube 2: toluene-4-sulfonic acid / methanol / 16 h / 20 °C View Scheme

: 5244-34-8
2,2'-ethane-1,2-diylbissulfanyl-bis-ethanol

: 55182-73-5
dodec-3-yn-1-ol

: 32451-95-9
(Z)-Dodec-3-en-1-ol

Conditions

Conditions	Yield
In ethyl acetate	2.95 g (91.6%)

: C18H38OSi

: 32451-95-9
(Z)-Dodec-3-en-1-ol

Conditions

Conditions	Yield
With tetrabutyl ammonium fluoride In tetrahydrofuran; dichloromethane at 20℃; Inert atmosphere;

: (+/-)-6-heptyl-3,6-dihydro-2H-pyran

: 32451-95-9
(Z)-Dodec-3-en-1-ol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: tris(pentafluorophenyl)borate / dichloromethane / 20 °C / Inert atmosphere 2: tetrabutyl ammonium fluoride / tetrahydrofuran; dichloromethane / 20 °C / Inert atmosphere View Scheme

: 4048-42-4
1-dodecen-3-ol

: 32451-95-9
(Z)-Dodec-3-en-1-ol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: hydrogenchloride / benzene 2: 4,4'-di-tert-butylbiphenyl; lithium / tetrahydrofuran / 0 - 20 °C View Scheme

: C13H25ClO

: 32451-95-9
(Z)-Dodec-3-en-1-ol

Conditions

Conditions	Yield
With 4,4'-di-tert-butylbiphenyl; lithium In tetrahydrofuran at 0 - 20℃; Wittig Rearrangement;

: C12H23ClO

A: 32451-95-9
(Z)-Dodec-3-en-1-ol

B: 68900-87-8
(E)-3-dodecene-1-ol

Conditions

Conditions	Yield
With 1,4-di-tert-butylbenzene; lithium In tetrahydrofuran at 0 - 20℃; Wittig Rearrangement;

: 124-19-6
nonan-1-al

: 32451-95-9
(Z)-Dodec-3-en-1-ol

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: tetrahydrofuran / 0 - 20 °C 2: hydrogenchloride / benzene 3: lithium; 1,4-di-tert-butylbenzene / tetrahydrofuran / 0 - 20 °C View Scheme

: 35329-42-1
undec-1-en-3-ol

: 32451-95-9
(Z)-Dodec-3-en-1-ol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: hydrogenchloride / benzene 2: lithium; 1,4-di-tert-butylbenzene / tetrahydrofuran / 0 - 20 °C View Scheme

: 32451-95-9
(Z)-Dodec-3-en-1-ol

: 98-59-9
p-toluenesulfonyl chloride

: 90486-47-8
(3Z)-1-O-(p-tolylsulfonyl)dodec-3-en-1-ol

Conditions

Conditions	Yield
With dmap; triethylamine In dichloromethane at -4℃; for 7h;	98%
In pyridine at 2 - 5℃; for 20h;
In pyridine

: 107-93-7
(E)-but-2-enoic acid

: 32451-95-9
(Z)-Dodec-3-en-1-ol

: (Z)-dodec-3-en-1-yl (E)-2-butenoate

Conditions

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide In dichloromethane for 4h; Ambient temperature;	93%

: 625-35-4, 3488-22-0, 10487-71-5
trans-chrotonyl chloride

: 32451-95-9
(Z)-Dodec-3-en-1-ol

: (Z)-dodec-3-en-1-yl (E)-2-butenoate

Conditions

Conditions	Yield
With pyridine at 0 - 20℃; for 26h;	86%
With pyridine for 12h; Ambient temperature;	77%

: 32451-95-9
(Z)-Dodec-3-en-1-ol

: 86982-50-5
(3Z)-1-bromododec-3-ene

Conditions

Conditions	Yield
With carbon tetrabromide; triphenylphosphine In dichloromethane at 0℃; for 0.333333h;	83%
Multi-step reaction with 2 steps 1: triethylamine / dichloromethane / 0 °C 2: lithium bromide / acetone / 3 h / Reflux View Scheme

: 32451-95-9
(Z)-Dodec-3-en-1-ol

: 68141-15-1
(Z)-3-dodecenal

Conditions

Conditions	Yield
With pyridinium chlorochromate In dichloromethane for 2h;	56%
With Dess-Martin periodane In dichloromethane at 20℃; for 3h; Dess-Martin Oxidation;
With Dess-Martin periodane In dichloromethane at 20℃; for 3h;
With Dess-Martin periodane In dichloromethane at 20℃; for 3.08h;

: 32451-95-9
(Z)-Dodec-3-en-1-ol

: 75-36-5
acetyl chloride

: 38363-24-5
(Z)-3-dodecen-1-yl acetate

Conditions

Conditions	Yield
In acetic acid at 25 - 35℃; for 48h;

: 32451-95-9
(Z)-Dodec-3-en-1-ol

: 102838-90-4
6-thiaoleic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: pyridine 2: n-BuLi / tetrahydrofuran; hexamethylphosphoric acid triamide View Scheme

: 32451-95-9
(Z)-Dodec-3-en-1-ol

: 86982-53-8
(3Z,6Z)-2,2-Dimethyl-pentadeca-3,6-dienal

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 83 percent / CBr4, PPh3 / CH2Cl2 / 0.33 h / 0 °C 2: 82 percent / acetonitrile / 72 h / Heating 3: 1.) n-BuLi / 1.) THF, 0 deg C 2.) -78 to room temp. 4: 47 percent / H2O, HCl / acetone / 47 h / Ambient temperature View Scheme

: 32451-95-9
(Z)-Dodec-3-en-1-ol

: 86982-52-7
2-((2Z,5Z)-1,1-Dimethyl-tetradeca-2,5-dienyl)-[1,3]dioxolane

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 83 percent / CBr4, PPh3 / CH2Cl2 / 0.33 h / 0 °C 2: 82 percent / acetonitrile / 72 h / Heating 3: 1.) n-BuLi / 1.) THF, 0 deg C 2.) -78 to room temp. View Scheme

: 32451-95-9
(Z)-Dodec-3-en-1-ol

: 86982-61-8
7,7-Dimethyleicosa-5(Z),8(Z),11(Z)-trienoic acid

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1: 83 percent / CBr4, PPh3 / CH2Cl2 / 0.33 h / 0 °C 2: 82 percent / acetonitrile / 72 h / Heating 3: 1.) n-BuLi / 1.) THF, 0 deg C 2.) -78 to room temp. 4: 47 percent / H2O, HCl / acetone / 47 h / Ambient temperature 5: 1.) KH / 1.) DMSO 2.) 1 h, room temp. View Scheme

: 32451-95-9
(Z)-Dodec-3-en-1-ol

: 86982-51-6
((Z)-Dodec-3-enyl)-triphenyl-phosphonium; bromide

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 83 percent / CBr4, PPh3 / CH2Cl2 / 0.33 h / 0 °C 2: 82 percent / acetonitrile / 72 h / Heating View Scheme

: 32451-95-9
(Z)-Dodec-3-en-1-ol

: 125198-04-1
(6E,8Z,11Z)-5-thia-6,8,11-eicosatrienoic acid

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 98 percent / DMAP, NEt3 / CH2Cl2 / 7 h / -4 °C 2: 83 percent / 18 h / 120 °C 3: 1.) n-butyllithium / 1.) THF, -20 deg C, 4 min, 2.) DMEU, from -78 deg C to -40 deg C, 4 h 4: 97 percent / LiOH*H2O / methanol / 2.5 h / 20 °C View Scheme

: 32451-95-9
(Z)-Dodec-3-en-1-ol

: 125198-10-9
methyl (6E,8Z,11Z)-6,8,11-eicosatrienoate

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 98 percent / DMAP, NEt3 / CH2Cl2 / 7 h / -4 °C 2: 83 percent / 18 h / 120 °C 3: 1.) n-butyllithium View Scheme

: 32451-95-9
(Z)-Dodec-3-en-1-ol

: 125198-09-6
methyl (8Z,11Z)-5-thia-8,11-eicosadienoate

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 98 percent / DMAP, NEt3 / CH2Cl2 / 7 h / -4 °C 2: 83 percent / 18 h / 120 °C 3: 1.) n-butyllithium View Scheme

: 32451-95-9
(Z)-Dodec-3-en-1-ol

: 125197-85-5
methyl (6E,8Z,11Z)-5-thia-6,8,11-eicosatrienoate

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 98 percent / DMAP, NEt3 / CH2Cl2 / 7 h / -4 °C 2: 83 percent / 18 h / 120 °C 3: 1.) n-butyllithium / 1.) THF, -20 deg C, 4 min, 2.) DMEU, from -78 deg C to -40 deg C, 4 h View Scheme

(3Z)-Dodec-3-en-1-ol Specification

The 3-Dodecen-1-ol, (3Z)-, with the CAS registry number 32451-95-9, is also known as (3Z)-Dodec-3-en-1-ol. Its EINECS registry number is 251-057-5. This chemical's molecular formula is C₁₂H₂₄O and molecular weight is 184.32. What's more, its IUPAC name is called (Z)-Dodec-3-en-1-ol.

Physical properties about 3-Dodecen-1-ol, (3Z)- are: (1)ACD/LogP: 4.80; (2)# of Rule of 5 Violations: 0; (3)#H bond acceptors: 1; (4)#H bond donors: 1; (5)#Freely Rotating Bonds: 10; (6)Polar Surface Area: 9.23 Å²; (7)Index of Refraction: 1.456; (8)Molar Refractivity: 59.23 cm³; (9)Molar Volume: 217.7 cm³; (10)Surface Tension: 30.9 dyne/cm; (11)Density: 0.846 g/cm³; (12)Flash Point: 97.6 °C; (13)Enthalpy of Vaporization: 58.77 kJ/mol; (14)Boiling Point: 268.1 °C at 760 mmHg; (15)Vapour Pressure: 0.00106 mmHg at 25 °C.

Preparation of 3-Dodecen-1-ol, (3Z)-: this chemical can be prepared by Dodec-3-yn-1-ol. This reaction needs reagent H₂ and solvent methanol. The yield is 96 %.

3-Dodecen-1-ol, (3Z)- can be prepared by Dodec-3-yn-1-ol.

Uses of 3-Dodecen-1-ol, (3Z)-: it is used to produce other chemicals. For example, it can react with Toluene-4-sulfonyl chloride to get (Z)-3-Dodecenyl p-toluenesulfonate. The reaction occurs with solvent pyridine at temperature of 2-5 °C. The reaction time is 20 hours.

3-Dodecen-1-ol, (3Z)- can react with Toluene-4-sulfonyl chloride to get (Z)-3-Dodecenyl p-toluenesulfonate.

You can still convert the following datas into molecular structure:
(1) SMILES: OCC\C=C/CCCCCCCC
(2) InChI: InChI=1S/C12H24O/c1-2-3-4-5-6-7-8-9-10-11-12-13/h9-10,13H,2-8,11-12H2,1H3/b10-9-
(3) InChIKey: BDGQTWOHKASHQU-KTKRTIGZSA-N

Product Name

(Z)-dodec-3-en-1-ol

Synthetic route

(3Z)-Dodec-3-en-1-ol Specification

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