1-(Trimethylsilyl)-1-propyne supplier

Name
1-(Trimethylsilyl)-1-propyne
EINECS 228-314-5
CAS No. 6224-91-5
Article Data36
CAS DataBase
Density 0.765 g/cm³
Solubility
Melting Point - 69 °C
Formula C₆H₁₂Si
Boiling Point 99-100 °C(lit.)
Molecular Weight 112.247
Flash Point 99.5 °C at 760 mmHg
Transport Information UN 1993
Appearance clear, colorless liquid.
Safety 16-26-36
Risk Codes 11-36/37/38
Molecular Structure
Hazard Symbols F; Xi
Synonyms Silane,trimethyl-1-propynyl- (6CI,7CI,8CI,9CI);1-(Trimethylsilyl)-1-propyne;1-(Trimethylsilyl)propyne;1-Methyl-2-trimethylsilylacetylene;1-Propynyltrimethylsilane;Methyl(trimethylsilyl)acetylene;Methyl(trimethylsilyl)ethyne;T 3728;Trimethyl(1-propyn-1-yl)silane;Trimethyl-1-propynylsilane;
PSA 0.00000
LogP 1.88710

Synthetic route

: 74-99-7
prop-1-yne

: 1066-54-2
trimethylsilylacetylene

: 6224-91-5
trimethyl(prop-1-ynyl)silane

Conditions

Conditions	Yield
(Me2SiCp''2UBu)2O*2THF In tetrahydrofuran at 66℃; for 44h;	100%

: 83268-94-4
C10H26OSi3

A: 6224-91-5
trimethyl(prop-1-ynyl)silane

B: 993-07-7
trimethylsilan

C: 1825-61-2
Methoxytrimethylsilane

D: 754-05-2
ethenyltrimethylsilane

Conditions

Conditions	Yield
at 650℃; under 0.0001 Torr;	A 18% B n/a C 87% D 28%

...Expand

: 78012-45-0
[3-(trimethylsilyl)prop-2-yn-1-yl]magnesium bromide

: 6224-91-5
trimethyl(prop-1-ynyl)silane

Conditions

Conditions	Yield
With hydrogenchloride In diethyl ether at 0 - 5℃;	86%

trimethyl(prop-1-ynyl)silane: trimethyl(prop-1-ynyl)silane

Conditions

Conditions	Yield
In various solvent(s) at 100℃; for 3h;	81.6%

trimethylsilylacetylene: trimethylsilylacetylene

: 74-88-4
methyl iodide

trimethyl(prop-1-ynyl)silane: trimethyl(prop-1-ynyl)silane

Conditions

Conditions	Yield
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0) at 20℃; for 3h; Inert atmosphere;	76%
Stage #1: methyl iodide With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; for 0.5h; Schlenk technique; Inert atmosphere; Stage #2: trimethylsilylacetylene at 20℃; for 4h; Schlenk technique; Inert atmosphere;

A trimethyl(prop-1-ynyl)silane: trimethyl(prop-1-ynyl)silane

B trimethylsilan: trimethylsilan

C

D: 754-05-2
ethenyltrimethylsilane

Conditions

Conditions	Yield
at 590℃; under 0.0001 Torr;	A 18% B n/a C 72% D 27%

...Expand

: 83268-92-2, 83268-93-3
C10H26OSi3

A: 6224-91-5
trimethyl(prop-1-ynyl)silane

B: 993-07-7
trimethylsilan

C: 1825-61-2
Methoxytrimethylsilane

D: 754-05-2
ethenyltrimethylsilane

Conditions

Conditions	Yield
at 650℃; under 0.0001 Torr;	A 17% B n/a C 55% D 16%

...Expand

: 129217-85-2
trimethyl (3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)prop-1-yn-1-yl)silane

: 6224-91-5
trimethyl(prop-1-ynyl)silane

Conditions

Conditions	Yield
With trifluoroacetic acid In chloroform-d1 at 20℃; for 18h; Inert atmosphere; regioselective reaction;	23%

: 2857-97-8
trimethylsilyl bromide

: 16466-97-0, 13254-27-8
1-propynylmagnesium bromide

: 6224-91-5
trimethyl(prop-1-ynyl)silane

: 75-77-4
chloro-trimethyl-silane

: 4529-04-8
1-propynyl lithium

: 6224-91-5
trimethyl(prop-1-ynyl)silane

Conditions

Conditions	Yield
In diethyl ether
In diethylene glycol dimethyl ether
In diethyl ether for 30h; Heating; Yield given;

: 75-77-4
chloro-trimethyl-silane

: 106-96-7
propargyl bromide

: 6224-91-5
trimethyl(prop-1-ynyl)silane

Conditions

Conditions	Yield
With magnesium In N,N,N,N,N,N-hexamethylphosphoric triamide at 100 - 110℃;

: 75-77-4
chloro-trimethyl-silane

: 74-99-7
prop-1-yne

: 6224-91-5
trimethyl(prop-1-ynyl)silane

Conditions

Conditions	Yield
(i) nBuLi, THF, hexane, (ii) /BRN= 1209232/; Multistep reaction;
(i) nBuLi, hexane, (ii) /BRN= 1209232/; Multistep reaction;
(i) nBuLi, hexane, (ii) /BRN= 1209232/, pentane, THF; Multistep reaction;

: 75-77-4
chloro-trimethyl-silane

: 557-93-7
2-bromoprop-1-ene

A: 6224-91-5
trimethyl(prop-1-ynyl)silane

B: 18163-07-0
2-(trimethylsilyl)propene

C: 21752-80-7
1,3-bis(trimethylsilyl)propyne

D: 4529-04-8
1-propynyl lithium

Conditions

Conditions	Yield
With lithium 1.) ether, 3 h, reflux, ultrasound; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given;

...Expand

: 75-77-4
chloro-trimethyl-silane

: 61668-36-8
bromo-2 trimethylsilyloxy-1 propene-1

A: 6224-91-5
trimethyl(prop-1-ynyl)silane

B: 154581-92-7
(Z)-2-Trimethylsilanyl-1-trimethylsilanyloxy-propene

Conditions

Conditions	Yield
With tert.-butyl lithium; sodium carbonate 1.) pentane, THF, -70 deg C, 45 min; 2.) -70 deg C, 50 min; 3.) 0 deg C, 10 min; Multistep reaction;

...Expand

: 74-99-7
prop-1-yne

: 1066-54-2
trimethylsilylacetylene

: 6224-91-5
trimethyl(prop-1-ynyl)silane

Conditions

Conditions	Yield
(Me2SiCp''2UBu)2O*2THF In tetrahydrofuran at 66℃; for 44h;	100%

: 83268-94-4
C10H26OSi3

A: 6224-91-5
trimethyl(prop-1-ynyl)silane

B: 993-07-7
trimethylsilan

C: 1825-61-2
Methoxytrimethylsilane

D: 754-05-2
ethenyltrimethylsilane

Conditions

Conditions	Yield
at 650℃; under 0.0001 Torr;	A 18% B n/a C 87% D 28%

...Expand

: 78012-45-0
[3-(trimethylsilyl)prop-2-yn-1-yl]magnesium bromide

: 6224-91-5
trimethyl(prop-1-ynyl)silane

Conditions

Conditions	Yield
With hydrogenchloride In diethyl ether at 0 - 5℃;	86%

: 75-77-4
chloro-trimethyl-silane

: 10486-71-2
sodium propynide

: 6224-91-5
trimethyl(prop-1-ynyl)silane

Conditions

Conditions	Yield
In various solvent(s) at 100℃; for 3h;	81.6%

: 1066-54-2
trimethylsilylacetylene

: 74-88-4
methyl iodide

: 6224-91-5
trimethyl(prop-1-ynyl)silane

Conditions

Conditions	Yield
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0) at 20℃; for 3h; Inert atmosphere;	76%
Stage #1: methyl iodide With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine at 20℃; for 0.5h; Schlenk technique; Inert atmosphere; Stage #2: trimethylsilylacetylene at 20℃; for 4h; Schlenk technique; Inert atmosphere;

: 83268-89-7
2-cyclopropyl-2-methoxyhexamethyltrisilane

A: 6224-91-5
trimethyl(prop-1-ynyl)silane

B: 993-07-7
trimethylsilan

C: 1825-61-2
Methoxytrimethylsilane

D: 754-05-2
ethenyltrimethylsilane

Conditions

Conditions	Yield
at 590℃; under 0.0001 Torr;	A 18% B n/a C 72% D 27%

...Expand

: 83268-92-2, 83268-93-3
C10H26OSi3

A: 6224-91-5
trimethyl(prop-1-ynyl)silane

B: 993-07-7
trimethylsilan

C: 1825-61-2
Methoxytrimethylsilane

D: 754-05-2
ethenyltrimethylsilane

Conditions

Conditions	Yield
at 650℃; under 0.0001 Torr;	A 17% B n/a C 55% D 16%

...Expand

: 129217-85-2
trimethyl (3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)prop-1-yn-1-yl)silane

: 6224-91-5
trimethyl(prop-1-ynyl)silane

Conditions

Conditions	Yield
With trifluoroacetic acid In chloroform-d1 at 20℃; for 18h; Inert atmosphere; regioselective reaction;	23%

: 2857-97-8
trimethylsilyl bromide

: 16466-97-0, 13254-27-8
1-propynylmagnesium bromide

: 6224-91-5
trimethyl(prop-1-ynyl)silane

: 75-77-4
chloro-trimethyl-silane

: 4529-04-8
1-propynyl lithium

: 6224-91-5
trimethyl(prop-1-ynyl)silane

Conditions

Conditions	Yield
In diethyl ether
In diethylene glycol dimethyl ether
In diethyl ether for 30h; Heating; Yield given;

: 75-77-4
chloro-trimethyl-silane

: 106-96-7
propargyl bromide

: 6224-91-5
trimethyl(prop-1-ynyl)silane

Conditions

Conditions	Yield
With magnesium In N,N,N,N,N,N-hexamethylphosphoric triamide at 100 - 110℃;

: 75-77-4
chloro-trimethyl-silane

: 74-99-7
prop-1-yne

: 6224-91-5
trimethyl(prop-1-ynyl)silane

Conditions

Conditions	Yield
(i) nBuLi, THF, hexane, (ii) /BRN= 1209232/; Multistep reaction;
(i) nBuLi, hexane, (ii) /BRN= 1209232/; Multistep reaction;
(i) nBuLi, hexane, (ii) /BRN= 1209232/, pentane, THF; Multistep reaction;

: 75-77-4
chloro-trimethyl-silane

: 557-93-7
2-bromoprop-1-ene

A: 6224-91-5
trimethyl(prop-1-ynyl)silane

B: 18163-07-0
2-(trimethylsilyl)propene

C: 21752-80-7
1,3-bis(trimethylsilyl)propyne

D: 4529-04-8
1-propynyl lithium

Conditions

Conditions	Yield
With lithium 1.) ether, 3 h, reflux, ultrasound; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given;

...Expand

: 75-77-4
chloro-trimethyl-silane

: 61668-36-8
bromo-2 trimethylsilyloxy-1 propene-1

A: 6224-91-5
trimethyl(prop-1-ynyl)silane

B: 154581-92-7
(Z)-2-Trimethylsilanyl-1-trimethylsilanyloxy-propene

Conditions

Conditions	Yield
With tert.-butyl lithium; sodium carbonate 1.) pentane, THF, -70 deg C, 45 min; 2.) -70 deg C, 50 min; 3.) 0 deg C, 10 min; Multistep reaction;

...Expand

: 75-77-4
chloro-trimethyl-silane

: ((Z)-2-Bromo-1-methyl-vinyloxy)-trimethyl-silane

A: 6224-91-5
trimethyl(prop-1-ynyl)silane

B: (Z)-1-Trimethylsilanyl-2-trimethylsilanyloxy-propene

Conditions

Conditions	Yield
With tert.-butyl lithium; sodium carbonate 1.) pentane, THF, -70 deg C, 45 min; 2.) -70 deg C, 50 min; 3.) 0 deg C, 10 min; Yield given. Multistep reaction;

...Expand

: 62827-97-8
Bis(trimethylsilyl)thioketene

A: 6224-91-5
trimethyl(prop-1-ynyl)silane

B: 7796-59-0
tetramethylcyclodisilthiane

C: Trimethylsilanyl-ethenethione

D: 14630-40-1
Bis(trimethylsilyl)ethyne

Conditions

Conditions	Yield
at 768℃; flash vacuum pyrolysis;	A 13 % Chromat. B 4 % Chromat. C 17 % Chromat. D 17 % Chromat.

...Expand

: 62827-97-8
Bis(trimethylsilyl)thioketene

A: 6224-91-5
trimethyl(prop-1-ynyl)silane

B: 7796-59-0
tetramethylcyclodisilthiane

C: 2,2,4,4-tetramethyl-2,4-disilathiethane

D: 14630-40-1
Bis(trimethylsilyl)ethyne

Conditions

Conditions	Yield
at 768℃; flash vacuum pyrolysis;	A 13 % Chromat. B 4 % Chromat. C 8 % Chromat. D 17 % Chromat.

...Expand

: 62827-97-8
Bis(trimethylsilyl)thioketene

A: 6224-91-5
trimethyl(prop-1-ynyl)silane

B: Trimethylsilanyl-ethenethione

C: 2,2,4,4-tetramethyl-2,4-disilathiethane

D: 14630-40-1
Bis(trimethylsilyl)ethyne

Conditions

Conditions	Yield
at 768℃; flash vacuum pyrolysis;	A 13 % Chromat. B 17 % Chromat. C 8 % Chromat. D 17 % Chromat.

...Expand

: 32501-93-2
1-(Phenylsulfonyl)-2-(trimethylsilyl)acetylene

: 917-54-4
methyllithium

A: 6224-91-5
trimethyl(prop-1-ynyl)silane

B: 98-11-3
benzenesulfonic acid

Conditions

Conditions	Yield
In tetrahydrofuran 1.) -78 deg C; 2.) up to RT; Yields of byproduct given;

...Expand

: 141862-01-3
methyl 3-(trimethylsilyl)prop-2-ynyl carbonate

A: 6224-91-5
trimethyl(prop-1-ynyl)silane

B: 1578-53-6
1,6--1,5-hexadiyne

C: 3,6-Bis(trimethylsilyl)-1,2-hexadien-5-yne

Conditions

Conditions	Yield
tetrakis(triphenylphosphine) palladium(0) In toluene for 2h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

...Expand

: 167275-01-6
ethyl 3-(trimethylsilyl)prop-2-ynyl carbonate

A: 6224-91-5
trimethyl(prop-1-ynyl)silane

B: 1578-53-6
1,6--1,5-hexadiyne

C: 3,6-Bis(trimethylsilyl)-1,2-hexadien-5-yne

Conditions

Conditions	Yield
tetrakis(triphenylphosphine) palladium(0) In toluene for 1h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

...Expand

: 3-(Trimethylsilyl)propargyl isopropyl carbonate

A: 6224-91-5
trimethyl(prop-1-ynyl)silane

B: 1578-53-6
1,6--1,5-hexadiyne

C: 3,6-Bis(trimethylsilyl)-1,2-hexadien-5-yne

Conditions

Conditions	Yield
tetrakis(triphenylphosphine) palladium(0) In toluene for 1.5h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

...Expand

: 74-99-7
prop-1-yne

Me3SiHal: Me3SiHal

: 6224-91-5
trimethyl(prop-1-ynyl)silane

Conditions

Conditions	Yield
(i) EtMgBr, ether, (ii) Me3SiHal; Multistep reaction;

: 36551-06-1
3-(tetrahydropyran-2-yloxy)-1-trimethylsilylprop-1-yne

: 6224-91-5
trimethyl(prop-1-ynyl)silane

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: ethanol / 9 h / 80 °C 2: pyridine / diethyl ether 3: Pd(PPh3)4 / toluene / 1 h / Heating View Scheme
Multi-step reaction with 3 steps 1: ethanol / 9 h / 80 °C 2: pyridine / diethyl ether 3: Pd(PPh3)4 / toluene / 1.5 h / Heating View Scheme
Multi-step reaction with 3 steps 1: ethanol / 9 h / 80 °C 2: pyridine / diethyl ether 3: Pd(PPh3)4 / toluene / 2 h / Heating View Scheme

: 5272-36-6
3-trimethylsilyl-2-propyn-1-ol

: 6224-91-5
trimethyl(prop-1-ynyl)silane

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: pyridine / diethyl ether 2: Pd(PPh3)4 / toluene / 1 h / Heating View Scheme
Multi-step reaction with 2 steps 1: pyridine / diethyl ether 2: Pd(PPh3)4 / toluene / 1.5 h / Heating View Scheme
Multi-step reaction with 2 steps 1: pyridine / diethyl ether 2: Pd(PPh3)4 / toluene / 2 h / Heating View Scheme

: 14630-40-1
Bis(trimethylsilyl)ethyne

pentacarbonyl<(cyclopropyl)methoxymethylene>chromium: pentacarbonyl<(cyclopropyl)methoxymethylene>chromium

: 6224-91-5
trimethyl(prop-1-ynyl)silane

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 75 percent / AlCl3 / CH2Cl2 / 12 h / Ambient temperature 2: tetrahydrofuran / 1.) -78 deg C; 2.) up to RT View Scheme

: 124127-77-1
RuCo2(CO)9(μ3-C(Me)SiMe3)

: 6224-91-5
trimethyl(prop-1-ynyl)silane

Conditions

Conditions	Yield
With I2 In tetrachloromethane to RuCo-compd. I2 added; (1)H-NMR;

: 129217-85-2
trimethyl (3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)prop-1-yn-1-yl)silane

A: 6224-91-5
trimethyl(prop-1-ynyl)silane

B: 14657-22-8
allenyltrimethylsilane

Conditions

Conditions	Yield
With ethanol In chloroform-d1 at 20℃; for 18h; Inert atmosphere; regioselective reaction;

: C10H19BNO2Si(1-)*H(1+)

A: 6224-91-5
trimethyl(prop-1-ynyl)silane

B: 14657-22-8
allenyltrimethylsilane

Conditions

Conditions	Yield
With water In chloroform-d1 at 20℃; for 18h; Inert atmosphere; regioselective reaction;

: 6224-91-5
trimethyl(prop-1-ynyl)silane

: 3152-43-0
3,4-di-O-acetyl-D-xylal

: Acetic acid (3S,6R)-6-prop-1-ynyl-3,6-dihydro-2H-pyran-3-yl ester

Conditions

Conditions	Yield
With titanium tetrachloride In dichloromethane at -40 - -15℃; for 2h;	99%

: 6224-91-5
trimethyl(prop-1-ynyl)silane

: 23494-28-2
2-morpholin-4-yl-benzo[d][1,3]oxazin-4-one

: 1333318-67-4
2-methyl-1-(morpholine-4-carbonyl)-3-(trimethylsilyl)quinolin-4(1H)-one

Conditions

Conditions	Yield
With bis(1,5-cyclooctadiene)nickel(0); tributylphosphine In 5,5-dimethyl-1,3-cyclohexadiene at 80℃; for 24h; Inert atmosphere;	99%

: 6224-91-5
trimethyl(prop-1-ynyl)silane

: (R,E)-8-bromo-3,7-dimethyloct-6-en-1-yl benzoate

: (R,E)-3,7-dimethyl-11-(trimethylsilyl)undec-6-en-10-yn-1-ol

Conditions

Conditions	Yield
Stage #1: trimethyl(prop-1-ynyl)silane With n-butyllithium In tetrahydrofuran; hexane at -20℃; for 0.5h; Inert atmosphere; Stage #2: (R,E)-8-bromo-3,7-dimethyloct-6-en-1-yl benzoate In tetrahydrofuran; hexane at -20 - 0℃; for 12h; Inert atmosphere;	99%

: 6224-91-5
trimethyl(prop-1-ynyl)silane

: 615-43-0
2-iodophenylamine

: 135189-98-9
2-trimethylsilyl-3-methyl-1H-indole

Conditions

Conditions	Yield
With palladium diacetate; tetrabutyl-ammonium chloride; sodium carbonate; triphenylphosphine In N,N-dimethyl-formamide at 100℃; for 12h;	98%
With palladium diacetate; tetrabutyl-ammonium chloride; sodium carbonate; triphenylphosphine In N,N-dimethyl-formamide at 100℃; for 24h;	98%
Stage #1: 2-iodophenylamine With tetrabutyl-ammonium chloride; palladium diacetate; sodium carbonate; triphenylphosphine In N,N-dimethyl-formamide at 20℃; for 0.166667h; Inert atmosphere; Stage #2: trimethyl(prop-1-ynyl)silane In N,N-dimethyl-formamide at 100℃; for 22h; Inert atmosphere; regioselective reaction;	91%

: 6224-91-5
trimethyl(prop-1-ynyl)silane

A: 3510-70-1
trimethylpropylsilane

B: 17680-01-2
1-(trimethylsilyl)-1-propene

Conditions

Conditions	Yield
With hydrogen; copper-palladium; silica gel In ethanol at 25℃; under 760 Torr; Kinetics;	A n/a B 98%

: 6224-91-5
trimethyl(prop-1-ynyl)silane

: 17680-01-2
1-(trimethylsilyl)-1-propene

Conditions

Conditions	Yield
With hydrogen; copper-palladium; silica gel In ethanol at 25℃; under 760.051 Torr;	98%
With diisobutylaluminium hydride In diethyl ether Inert atmosphere;
With tri-n-butyl-tin hydride In tetrahydrofuran Inert atmosphere;

: 6224-91-5
trimethyl(prop-1-ynyl)silane

: 80594-34-9
1-Oxo-1-(trimethylsilyl)-2-propanone

Conditions

Conditions	Yield
With [1,4,7-Me3-1,4,7-triazacyclononane(CF3CO2)RuIVO2]ClO4; trifluoroacetic acid In acetonitrile at 20℃; for 5h;	98%

: 6224-91-5
trimethyl(prop-1-ynyl)silane

: 78-79-5
isoprene

: 1309761-62-3
(2,4-dimethylcyclohexa-1,4-dienyl)trimethylsilane

Conditions

Conditions	Yield
With cobalt(II) bromide-[1,2-bis(diphenylphosphino)ethane]; zinc(II) iodide; zinc In dichloromethane at 20℃; Diels-Alder reaction; Inert atmosphere; regioselective reaction;	98%

: 6224-91-5
trimethyl(prop-1-ynyl)silane

: 591-18-4
1-Bromo-3-iodobenzene

: 66952-36-1
1-bromo-3-(prop-1-yn-1-yl)benzene

Conditions

Conditions	Yield
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); tetrabutyl ammonium fluoride; triethylamine In tetrahydrofuran; toluene at 20℃; for 17h; Schlenk technique; Inert atmosphere;	98%
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); tetrafluoroammonium fluoride; triethylamine In tetrahydrofuran; toluene at 20℃; for 17h; Inert atmosphere;	86%
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); tetrafluoroammonium fluoride; triethylamine In tetrahydrofuran; toluene at 20℃; for 17h; Inert atmosphere;	86%
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); tetrafluoroammonium fluoride; triethylamine In tetrahydrofuran; toluene at 20℃; for 17h; Inert atmosphere;	86%
With triethylamine; copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); tetrabutyl ammonium fluoride In tetrahydrofuran; toluene at 20℃; Inert atmosphere;	80%

: 6224-91-5
trimethyl(prop-1-ynyl)silane

: 91230-06-7
3--2-methylprop-1-ene

: tert-butyl ((1E,4E)-2,4-dimethyl-5-(trimethylsilyl)penta-1,4-dien-1-yl)carbamate

Conditions

Conditions	Yield
With cyclopentadienylruthenium(II) trisacetonitrile hexafluorophosphate In acetone at 20 - 80℃; Inert atmosphere; stereoselective reaction;	98%

: 6224-91-5
trimethyl(prop-1-ynyl)silane

: 29619-42-9
1,1'-[ethyne-1,2-diylbis(4,1-phenylene)]diethanone

: 75883-03-3
4'-(2-trimethylsilylethynyl)acetophenone

Conditions

Conditions	Yield
With [(Ph3SiO)3Mo≡CC6H4OMe] In toluene at 20℃; for 2h; Inert atmosphere; Molecular sieve;	98%

: 6224-91-5
trimethyl(prop-1-ynyl)silane

: 1616877-82-7
N-(quinolin-8-yl)-2-methylacrylamide

: 3,6-dimethyl-5-trimethylsilyl-1-(quinolin-8-yl)pyridin-2(1H)-one

Conditions

Conditions	Yield
Stage #1: trimethyl(prop-1-ynyl)silane; N-(quinolin-8-yl)-2-methylacrylamide With 1,2-Dichloropropane; ZnBr2*C6H16N2; (trimethylsilyl)methylmagnesium chloride; cis-1,2-bis-(diphenylphosphino)ethene In tetrahydrofuran at 20℃; Schlenk technique; Stage #2: With iron(III)-acetylacetonate In tetrahydrofuran at 40℃; for 20h; Reagent/catalyst; Schlenk technique;	98%

: 6224-91-5
trimethyl(prop-1-ynyl)silane

: 232276-45-8
N-(2,6-dichlorobenzoyl)-O-(trifluoromethanesulfonyl)-L-tyrosine methyl ester

: C20H17Cl2NO3

Conditions

Conditions	Yield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; copper(l) iodide; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 90℃; for 24h;	98%

: 6224-91-5
trimethyl(prop-1-ynyl)silane

: 14857-34-2
dimethyl(ethoxy)silane

: C10H24OSi2

Conditions

Conditions	Yield
With cross-linked polysiloxane stabilized platinum nanoparticles (Pt-Nano) In benzene at 20℃; for 10h; Inert atmosphere; Schlenk technique; regioselective reaction;	98%

: 6224-91-5
trimethyl(prop-1-ynyl)silane

: 1066-35-9
dimethylmonochlorosilane

: C8H19ClSi2

Conditions

Conditions	Yield
With cross-linked polysiloxane stabilized platinum nanoparticles (Pt-Nano) In benzene at 20℃; for 10h; Inert atmosphere; Schlenk technique; regioselective reaction;	98%

: 6224-91-5
trimethyl(prop-1-ynyl)silane

: 1789-58-8
ethyldichlorosilane

: C8H18Cl2Si2

Conditions

Conditions	Yield
With cross-linked polysiloxane stabilized platinum nanoparticles (Pt-Nano) In benzene at 20℃; for 10h; Inert atmosphere; Schlenk technique; regioselective reaction;	98%

: 6224-91-5
trimethyl(prop-1-ynyl)silane

: 998-30-1
Triethoxysilane

: (E)-triethoxy(1-(trimethylsilyl)prop-1-en-2-yl)silane

Conditions

Conditions	Yield
With cross-linked polysiloxane stabilized platinum nanoparticles (Pt-Nano) In benzene at 20℃; for 10h; Inert atmosphere; Schlenk technique; regioselective reaction;	97%
With cyclopentadienylruthenium(II) trisacetonitrile hexafluorophosphate In dichloromethane at 20℃; for 24h; Inert atmosphere; stereoselective reaction;	88%

1-(Trimethylsilyl)-1-propyne Specification

The Silane,trimethyl-1-propyn-1-yl-, with the CAS registry number 6224-91-5 and EINECS registry number 228-314-5, has the systematic name of trimethyl(prop-1-yn-1-yl)silane. It is a kind of clear colorless liquid, and belongs to the following product categories: Acetylenes; Diyne Compounds (LB Films); Ethynylsilanes; Functional Materials; Functionalized Acetylenes; LB Films; Si (Classes of Silicon Compounds); Si-(C)4 Compounds; Silicon Compounds (for Synthesis); Synthetic Organic Chemistry. The molecular formula of the chemical is C₆H₁₂Si. What's more, it should be stored at 0-6°C.

The characteristics of Silane,trimethyl-1-propyn-1-yl- are as followings: (1)ACD/LogP: 2.70; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.7; (4)ACD/LogD (pH 7.4): 2.7; (5)ACD/BCF (pH 5.5): 66.54; (6)ACD/BCF (pH 7.4): 66.54; (7)ACD/KOC (pH 5.5): 702.36; (8)ACD/KOC (pH 7.4): 702.36; (9)#H bond acceptors: 0; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 0 Å²; (13)Index of Refraction: 1.413; (14)Molar Refractivity: 36.56 cm³; (15)Molar Volume: 146.6 cm³; (16)Polarizability: 14.49×10^-24cm³; (17)Surface Tension: 19.5 dyne/cm; (18)Density: 0.765 g/cm³; (19)Enthalpy of Vaporization: 32.48 kJ/mol; (20)Boiling Point: 99.5 °C at 760 mmHg; (21)Vapour Pressure: 43.9 mmHg at 25°C.

Uses of Silane,trimethyl-1-propyn-1-yl-: It can react with chloro-trimethyl-silane to produce 1-propyne-1,3-diylbis(trimethyl-silane).

You should be cautious while dealing with this chemical. It is a kind of highly flammmable chemical which irritates to eyes, respiratory system and skin. Therefore, you had better take the following instructions: Keep away from sources of ignition - No smoking; Wear suitable protective clothing, and if in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice.

Addtionally, the following datas could be converted into the molecular structure:
(1)SMILES: C(#C[Si](C)(C)C)C
(2)InChI: InChI=1/C6H12Si/c1-5-6-7(2,3)4/h1-4H3
(3)InChIKey: DCGLONGLPGISNX-UHFFFAOYAK

Product Name

1-(Trimethylsilyl)-1-propyne

Synthetic route

1-(Trimethylsilyl)-1-propyne Specification

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