1-Methyl-3-nitro-1-nitrosoguanidine supplier

Name
1-Methyl-3-nitro-1-nitrosoguanidine
EINECS 200-730-1
CAS No. 70-25-7
Article Data4
CAS DataBase
Density 1.7979 (rough estimate)
Solubility Reacts violently
Melting Point 118 ºC (dec.)
Formula C2H5 N5 O3
Boiling Point 267.16°C (rough estimate)
Molecular Weight 147.093
Flash Point 120.541oC
Transport Information UN 1325
Appearance yellow to pink crystals
Safety Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Poison by ingestion, intraperitoneal, and intravenous routes. Moderately toxic by subcutaneous route. Experimental reproductive effects. Human mutation data reported. An explosive sensitive to heat or impact. Flammable when exposed to heat or flame; can react vigorously with oxidizing materials. When heated to decomposition it emits very toxic fumes of NO_x. See also N-NITROSO COMPOUNDS.
Risk Codes R45;R20;R36/38;R51/53
Molecular Structure
Hazard Symbols
Synonyms Guanidine,1-methyl-3-nitro-1-nitroso- (6CI,8CI); 1-Methyl-1-nitroso-2-nitroguanidine;1-Methyl-1-nitroso-3-nitroguanidine; 1-Methyl-3-nitro-1-nitrosoguanidine;1-Nitroso-3-nitro-1-methylguanidine; MNNG; Methylnitronitrosoguanidine;N-Methyl-N-nitroso-N'-nitroguanidine; N-Methyl-N1-nitro-N-nitrosoguanidine;N-Methyl-N'-nitro-N-nitrosoguanadine; N-Methyl-N'-nitro-N-nitrosoguanidine;N-Methyl-nitroso-N'-nitroguanidine; N-Nitroso-N-methyl-N'-nitroguanidine;N-Nitroso-N-methylnitroguanidine; N-Nitroso-N'-nitro-N-methylguanidine; NSC9369; NTG; Nitrosoguanidine
PSA 114.37000
LogP 0.32950

Synthetic route

: 4245-76-5
N-methyl-N'-nitroguanidine

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

Conditions

Conditions	Yield
With nitric acid; sodium nitrite at 10℃;

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: 400736-91-6
(2E,4E)-5-Bromo-2,4-dimethyl-penta-2,4-dienoic acid

: 400736-94-9
(2E,4E)-5-bromo-2,4-dimethyl-penta-2,4-dienoic acid methyl ester

Conditions

Conditions	Yield
Stage #1: N-Methyl-N'-nitro-N-nitrosoguanidine With potassium hydroxide In diethyl ether at 0℃; for 0.25h; Stage #2: (2E,4E)-5-Bromo-2,4-dimethyl-penta-2,4-dienoic acid In diethyl ether	99%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: 1009365-40-5
C17H21FO3

: 1009367-58-1
methyl 2-(9-(4-fluorophenyl)-3-hydroxybicyclo[3.3.1]nonan-9-yl)acetate

Conditions

Conditions	Yield
Stage #1: N-Methyl-N'-nitro-N-nitrosoguanidine With potassium hydroxide In diethyl ether; water at 0℃; for 0.0833333h; Stage #2: C17H21FO3 In diethyl ether; dichloromethane at 0℃; for 0.166667h;	99%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: 15647-47-9
5-benzoylaminopentanoic acid

: 17079-25-3
methyl N-benzoyl-5-aminopentanoate

Conditions

Conditions	Yield
With sodium hydroxide In methanol; diethyl ether at 0℃;	99%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: 1310810-17-3
trans-methyl 4-(4-bromophenyl)but-2-enoate

: trans-methyl 2-(4-bromobenzyl)cyclopropanecarboxylate

Conditions

Conditions	Yield
Stage #1: N-Methyl-N'-nitro-N-nitrosoguanidine With potassium hydroxide In diethyl ether at 0℃; for 0.25h; Stage #2: trans-methyl 4-(4-bromophenyl)but-2-enoate With palladium diacetate In tetrahydrofuran; diethyl ether at 20℃; for 1h;	98%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: (4aR,6S,8S,8aR)-6-(3-azidopropoxy)-2,2-di-tert-butyl-8-(((4aR,6R,7S,8S,8aR)-2,2-di-tert-butyl-7,8-bis((tert-butyldimethylsilyl)oxy)hexahydropyrano[3,2-d][1,3,2]dioxasilin-6-yl)oxy)tetrahydropyrano[3,2-d][1,3,2]dioxasilin-7(6H)-one

: (2S,4a’R,6’S,8’S,8a’R)-6’-(3-azidopropoxy)-2’,2’-di-tert-butyl-8’-(((4aR,6R,7S,8S,8aR)-2,2-di-tert-butyl-7,8-bis((tert-butyldimethylsilyl)oxy)hexahydropyrano[3,2-d][1,3,2]dioxasilin-6-yl)oxy)tetrahydro-6’H-spiro[oxirane-2,7’-pyrano[3,2-d][1,3,2]dioxasiline]

Conditions

Conditions	Yield
With potassium hydroxide In diethyl ether; ethanol; water for 0.166667h; Inert atmosphere;	98%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: 110916-46-6
Mrz 2/138

: N-[2-(3,5-dimethyl-1-adamantyl)ethyl]-nitroguanidine

Conditions

Conditions	Yield
In diethyl ether; water at 22℃; for 1.5h;	96.5%
In diethyl ether; water at 20 - 22℃; for 0.5h;	96.5%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: (E)-methyl 4-(4-((3-phenoxybenzyl)oxy)bicyclo[2.2.1]heptan-1-yl)but-2-enoate

: methyl 2-((4-((3-phenoxybenzyl)oxy)bicyclo[2.2.1]heptan-1-yl)methyl)cyclopropanecarboxylate

Conditions

Conditions	Yield
Stage #1: N-Methyl-N'-nitro-N-nitrosoguanidine With palladium diacetate; potassium hydroxide In diethyl ether; water at 0℃; for 0.333333h; Stage #2: (E)-methyl 4-(4-((3-phenoxybenzyl)oxy)bicyclo[2.2.1]heptan-1-yl)but-2-enoate With palladium diacetate In tetrahydrofuran at 0 - 20℃; for 1h;	95%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: 89232-30-4
(2E)-N-benzylbut-2-enamide

: N-benzyl-2-methylcyclopropanecarboxamide

Conditions

Conditions	Yield
Stage #1: N-Methyl-N'-nitro-N-nitrosoguanidine With water; potassium hydroxide In diethyl ether at 0℃; for 0.25h; Stage #2: (2E)-N-benzylbut-2-enamide With palladium diacetate In tetrahydrofuran; diethyl ether at 20℃; for 1h;	94%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: N-benzoyl-N-((E)-2-butenyl)-5-aminopentanoic acid

: methyl N-benzoyl-N-((E)-2-butenyl)-5-aminopentanoate

Conditions

Conditions	Yield
With sodium hydroxide In diethyl ether at 0℃;	94%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: 3641-15-4
3-amino-1H-1,2,4-triazole-5-carbohydrazide

: N-(5'-amino-1H,1'H-[3,3'-bi(1,2,4-triazol)]-5-yl)nitramide

Conditions

Conditions	Yield
In methanol; water at 80℃; for 2h;	93%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: (E)-methyl-cis-3-(3-(4-bromophenyl)cyclobutyl)acrylate

: methyl trans-2-(cis-3-(4-bromophenyl)cyclobutyl)cyclopropanecarboxylate

Conditions

Conditions	Yield
Stage #1: N-Methyl-N'-nitro-N-nitrosoguanidine With water; potassium hydroxide In diethyl ether at 0℃; for 0.333333h; Stage #2: (E)-methyl-cis-3-(3-(4-bromophenyl)cyclobutyl)acrylate With palladium diacetate In tetrahydrofuran; diethyl ether at 0 - 20℃; for 1h;	92%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: (E)-5-(4-bromophenyl)pent-2-enoic acid ethyl ester

: trans-ethyl 2-(4-bromophenethyl)cyclopropanecarboxylate

Conditions

Conditions	Yield
Stage #1: N-Methyl-N'-nitro-N-nitrosoguanidine With potassium hydroxide In diethyl ether; water at -78 - 0℃; for 0.5h; Stage #2: (E)-5-(4-bromophenyl)pent-2-enoic acid ethyl ester With palladium diacetate In diethyl ether; water at 0 - 20℃; Stage #3: With acetic acid In diethyl ether at 20℃; for 0.5h;	91%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: (4-amino-furazan-3-yl)-acetic acid hydrazide

: C5H6N8O3

Conditions

Conditions	Yield
Stage #1: N-Methyl-N'-nitro-N-nitrosoguanidine; (4-amino-furazan-3-yl)-acetic acid hydrazide In methanol; water for 2h; Heating; Stage #2: With potassium hydroxide In water for 2h; Stage #3: With nitric acid In water at 50℃; pH=3;	90%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: silver nitrate

: 20236-50-4
silver (I) nitro cyanamide

Conditions

Conditions	Yield
In sodium hydroxide solvation of 16 g NaOH in 600 ml H2O and addition of 44.1 g of the guanidine under stirring at 0°C within 10 minutes, shaking for another 20 minutes and addition of 36 ml concentrated HNO3 in 150 ml H2O and 51 g AgNO3 in 150 ml H2O;; precipitation; washing with hot H2O;;	89.4%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: 1616364-26-1
3-methyl-4-(1-methyl-7-oxo-3-(pyridin-2-yl)-1,4,5,6,7,8-hexahydrocyclohepta[c]pyrazol-4-yl)benzoic acid

: 1616364-27-2
methyl 3-methyl-4-(1-methyl-7-oxo-3-(pyridin-2-yl)-1,4,5,6,7,8-hexahydrocyclohepta[c]pyrazol-4-yl)benzoate

Conditions

Conditions	Yield
With potassium hydroxide In tetrahydrofuran; diethyl ether; water at 0℃; Inert atmosphere;	88%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: (E)-methyl 5-(4-bromophenyl)pent-2-enoate

: trans-methyl 2-(4-bromophenethyl)cyclopropanecarboxylate

Conditions

Conditions	Yield
Stage #1: N-Methyl-N'-nitro-N-nitrosoguanidine With potassium hydroxide In diethyl ether; water at 0℃; for 0.25h; Stage #2: (E)-methyl 5-(4-bromophenyl)pent-2-enoate With palladium diacetate In tetrahydrofuran; diethyl ether; water at 20℃; for 1h;	88%

: 681128-21-2
tert-butyl (3R,5R,6S)-3-(2-methylprop-2-enyl)-2-oxo-5,6-diphenylmorpholine-4-carboxylate

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: 681128-22-3
tert-butyl (3R,5R,6S)-3-[(1-methylcyclopropyl)methyl]-2-oxo-5,6-diphenylmorpholine-4-carboxylate

Conditions

Conditions	Yield
Stage #1: N-Methyl-N'-nitro-N-nitrosoguanidine With potassium hydroxide In diethyl ether; water at 0℃; for 0.0833333h; Stage #2: tert-butyl (3R,5R,6S)-3-(2-methylprop-2-enyl)-2-oxo-5,6-diphenylmorpholine-4-carboxylate; palladium diacetate In tetrahydrofuran; diethyl ether at 0℃;	86%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: 3-Aminofurazan-4-carboxylic acid hydrazide

: 2-(4-aminofurazan-3-carbonyl)-N'-nitrohydrazine-1-carboximidamide

Conditions

Conditions	Yield
With water In methanol for 2h; Heating;	86%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: 37895-46-8
furoxancarboxylic acid hydrazide

: C5H5N7O4

Conditions

Conditions	Yield
Stage #1: N-Methyl-N'-nitro-N-nitrosoguanidine; furoxancarboxylic acid hydrazide In methanol; water for 2h; Heating; Stage #2: With potassium hydroxide In methanol; water for 2h; Stage #3: With nitric acid at 50℃; pH=3;	85%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: 89232-30-4
(2E)-N-benzylbut-2-enamide

: N-benzyl-2-methylcyclopropane-1-carboxamide

Conditions

Conditions	Yield
Stage #1: N-Methyl-N'-nitro-N-nitrosoguanidine With potassium hydroxide In diethyl ether; water at 20℃; for 0.166667h; Stage #2: (2E)-N-benzylbut-2-enamide; palladium diacetate In tetrahydrofuran; diethyl ether at 20℃; for 1h;	83%
Stage #1: N-Methyl-N'-nitro-N-nitrosoguanidine With potassium hydroxide In diethyl ether; water at -78 - 20℃; for 0.0833333h; Stage #2: (2E)-N-benzylbut-2-enamide; palladium diacetate In tetrahydrofuran; diethyl ether at 20℃; for 1h;

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: 187872-44-2
ethyl (E)-3-(3-fluoro-4-methoxyphenyl)acrylate

: 1234845-29-4
2-(3-fluoro-4-methoxyphenyl)cyclopropanecarboxylic acid ethyl ester

Conditions

Conditions	Yield
Stage #1: N-Methyl-N'-nitro-N-nitrosoguanidine With water; potassium hydroxide In diethyl ether at 0℃; for 0.0333333h; Stage #2: ethyl (E)-3-(3-fluoro-4-methoxyphenyl)acrylate; palladium diacetate In diethyl ether at 0 - 5℃; for 4h; Stage #3: With acetic acid In diethyl ether	83%
Stage #1: N-Methyl-N'-nitro-N-nitrosoguanidine With potassium hydroxide In diethyl ether; water at 0℃; Stage #2: ethyl (E)-3-(3-fluoro-4-methoxyphenyl)acrylate; palladium diacetate In diethyl ether; water at 0 - 5℃; Stage #3: With acetic acid In diethyl ether; water	83%

: 186581-53-3, 908094-01-9
diazomethane

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: 365554-36-5
3-(2-isopropylphenyl)propanoyl chloride

: 365554-38-7
1-diazo-4-(2-isopropylphenyl)butan-2-one

Conditions

Conditions	Yield
In dichloromethane	82%

...Expand

: 285139-32-4
N-[5-(N-4-toluenesulfonyl-amino)pyrimidin-4-yl]-L-4-(N,N-dimethylcarbarnyloxy)phenylalanine tert-butyl ester

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: 285139-33-5
N-[5-(N-methyl-N-4-toluenesulfonylamino)pyrimidin-4-yl]-L-4-(N,N-dimethylcarbarnyloxy)phenylalanine tert-butyl ester

Conditions

Conditions	Yield
Stage #1: N-Methyl-N'-nitro-N-nitrosoguanidine With sodium hydroxide In diethyl ether at 0℃; for 0.416667h; Stage #2: Stage #3: N-[5-(N-4-toluenesulfonyl-amino)pyrimidin-4-yl]-L-4-(N,N-dimethylcarbarnyloxy)phenylalanine tert-butyl ester In diethyl ether; dichloromethane at 0℃; for 0.25h;	82%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: 3-Aminofurazan-4-carboxylic acid hydrazide

: 3-amino-4-(5-nitramino-1,2,4-triazol-3-yl)furazan monohydrate

Conditions

Conditions	Yield
Stage #1: N-Methyl-N'-nitro-N-nitrosoguanidine; 3-Aminofurazan-4-carboxylic acid hydrazide In methanol; water for 2h; Heating; Stage #2: With potassium hydroxide In water for 2h; Stage #3: With nitric acid In water at 50℃; pH=3;	82%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: (R)-3-phenylbutanehydrazide

: (R)-N-(5-(2-phenylpropyl)-1H-1,2,4-triazol-3-yl)nitramide

Conditions

Conditions	Yield
With nitric acid; potassium hydroxide In water Reflux;	82%

: C29H38BrN3O5

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: methyl 4-[[(3S)-3-(4-bromophenylureido)-3-(tert-butoxycarbonyl)propyl](1,2,3,4-tetrahydro-1-naphthyl)amino]butyrate

Conditions

Conditions	Yield
Stage #1: N-Methyl-N'-nitro-N-nitrosoguanidine With potassium hydroxide In diethyl ether; water at 0℃; for 0.166667h; Stage #2: C29H38BrN3O5 In diethyl ether; dichloromethane; water at 0℃; for 0.5h;	81%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: 1581734-68-0
(2S,3R)-4-benzyl 1-tert-butyl 2-allyl-3-(3,3,3-trifluoropropyl)succinate

: 1581734-69-1
(2R,3S)-1-benzyl 4-tert-butyl 3-(cyclopropylmethyl)-2-(3,3,3-5 trifluoropropyl)succinate

Conditions

Conditions	Yield
With palladium diacetate; potassium hydroxide In diethyl ether; water at 0℃; for 3h;	81%
Stage #1: N-Methyl-N'-nitro-N-nitrosoguanidine With potassium hydroxide In diethyl ether at 0℃; Stage #2: (2S,3R)-4-benzyl 1-tert-butyl 2-allyl-3-(3,3,3-trifluoropropyl)succinate With palladium diacetate In diethyl ether; water at 0℃; for 3h;	81%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: 186581-53-3, 908094-01-9
diazomethane

Conditions

Conditions	Yield
With potassium hydroxide at -20.1℃;	80%
With potassium hydroxide
With potassium hydroxide In diethyl ether; water for 0.25h;

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: (4-amino-furazan-3-yl)-acetic acid hydrazide

: C5H8N8O4

Conditions

Conditions	Yield
In methanol; water for 2h; Heating;	80%

: 70-25-7
N-Methyl-N'-nitro-N-nitrosoguanidine

: (4aR,6S,8S,8aR)-6-(3-azidopropoxy)-2,2-di-tert-butyl-8-(((4aR,6R,7R,8S,8aR)-2,2-di-tert-butyl-7,8-bis((tert-butyldimethylsilyl)oxy)hexahydropyrano[3,2-d][1,3,2]dioxasilin-6-yl)oxy)tetrahydropyrano[3,2-d][1,3,2]dioxasilin-7(6H)-one

: (2S,4a’R,6’S,8’S,8a’R)-6’-(3-azidopropoxy)-2’,2’-di-tert-butyl-8’-(((4aR,6R,7R,8S,8aR)-2,2-di-tert-butyl-7,8-bis((tert-butyldimethylsilyl)oxy)hexahydropyrano[3,2-d][1,3,2]dioxasilin-6-yl)oxy)tetrahydro-6’H-spiro[oxirane-2,7’-pyrano[3,2-d][1,3,2]dioxasiline]

Conditions

Conditions	Yield
With potassium hydroxide In diethyl ether; ethanol; water for 0.166667h; Inert atmosphere;	78%

1-Methyl-3-nitro-1-nitrosoguanidine Chemical Properties

Molecular Formula: C₂H₅N₅O₃
Molar mass: 147.09 g/mol
Structure of 1-Methyl-3-nitro-1-nitrosoguanidine(70-25-7):

Synonyms of 1-Methyl-3-nitro-1-nitrosoguanidine(70-25-7):1-METHYL-3-NITRO-1-NITROSOGUANIDINE;MNNG;N-METHYL-N'-NITRO-N-NITROSOGUANIDINE;N-METHYL-N-NITROSO-N'-NITROGUANIDINE;DIAZOMETHANE PRECURSOR;1-Methyl-1-Nitroso-3-nitroguanidine;1-methyl-3-nitro-1-nitroso-guanidin;1-nitroso-3-nitro-1-methylguanidine
Water solubility: Reacts violently
Melting point: 118°C (dec.)
storage temp:0-6°C
Stability of 1-Methyl-3-nitro-1-nitrosoguanidine(70-25-7): Unstable. Heat, light and moisture sensitive. May explode if stored in sealed ampules. Highly flammable. Incompatible with aqueous solutions, bases, acids, oxidizing agents, reducing agents. Alkaline hydrolysis releases toxic and explosive gases. Reacts violently with water. May detonate under impact.
Appearance: yellow to pink crystals

1-Methyl-3-nitro-1-nitrosoguanidine Toxicity Data With Reference

1.	dnd-hmn:fbr 20 µmol/L	ENMUDM Environmental Mutagenesis. 7 (1985),267.
2.	sce-hmn:hla 300 nmol/L	CRNGDP Carcinogenesis. 5 (1984),593.
3.	ivn-rat TDLo:25 mg/kg (15D preg):ETA,TER	KFIZAO Kyoto-furitsu Ika Daigaku Zasshi. Journal of the Kyoto Prefectural School of Medicine. 84 (1975),23.
4.	orl-rat LD50:90 mg/kg	ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie. 91 (1978),183.
5.	scu-rat LD50:420 mg/kg	ZEKBAI Zeitschrift fuer Krebsforschung. 69 (1967),103.
6.	ivn-rat LD50:80 mg/kg	EJCAAH European Journal of Cancer. 16 (1980),395.
7.	ipr-mus LD50:66 mg/kg	JJIND8 JNCI, Journal of the National Cancer Institute. 62 (1979),911.
8.	ivn-mus LD50:37,300 µg/kg	NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program, Bethesda, MD 20205 JAN86 .
9.	orl-ham LD50:1070 mg/kg	CALEDQ Cancer Letters (Shannon, Ireland). 4 (1978),241.

1-Methyl-3-nitro-1-nitrosoguanidine Consensus Reports

NTP 10th Report on Carcinogens. IARC Cancer Review: Group 2A IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 248.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 4 ,1974,p. 183.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

1-Methyl-3-nitro-1-nitrosoguanidine Safety Profile

Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Poison by ingestion, intraperitoneal, and intravenous routes. Moderately toxic by subcutaneous route. Experimental reproductive effects. Human mutation data reported. An explosive sensitive to heat or impact. Flammable when exposed to heat or flame; can react vigorously with oxidizing materials. When heated to decomposition it emits very toxic fumes of NOx. See also N-NITROSO COMPOUNDS.
Hazard Codes:T,N,N,T
Risk Statements:
20: Harmful by inhalation
36: Irritating to the eyes
38: Irritating to the skin
45: May cause cancer
51: Toxic to aquatic organisms
53: May cause long-term adverse effects in the aquatic environment
Safety Statements:
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
53: Avoid exposure - obtain special instruction before use
61: Avoid release to the environment. Refer to special instructions safety data sheet

1-Methyl-3-nitro-1-nitrosoguanidine Standards and Recommendations

DOT Classification of 1-Methyl-3-nitro-1-nitrosoguanidine(70-25-7): EXPLOSIVE 1.1A; Label: EXPLOSIVE 1.1A

Product Name

1-Methyl-3-nitro-1-nitrosoguanidine

Synthetic route

1-Methyl-3-nitro-1-nitrosoguanidine Chemical Properties

1-Methyl-3-nitro-1-nitrosoguanidine Toxicity Data With Reference

1-Methyl-3-nitro-1-nitrosoguanidine Consensus Reports

1-Methyl-3-nitro-1-nitrosoguanidine Safety Profile

1-Methyl-3-nitro-1-nitrosoguanidine Standards and Recommendations

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