Product Name

  • Name

    2-(2-Hydroxyphenyl)benzothiazole

  • EINECS 222-299-9
  • CAS No. 3411-95-8
  • Article Data178
  • CAS DataBase
  • Density 1.337 g/cm3
  • Solubility
  • Melting Point 128-132 °C(lit.)
  • Formula C13H9NOS
  • Boiling Point 402.184 °C at 760 mmHg
  • Molecular Weight 227.287
  • Flash Point 197.034 °C
  • Transport Information
  • Appearance Off-white to yellow powder
  • Safety 26-37/39
  • Risk Codes 36/37/38
  • Molecular Structure Molecular Structure of 3411-95-8 (2-(2-Hydroxyphenyl)benzothiazole)
  • Hazard Symbols IrritantXi
  • Synonyms Phenol,o-2-benzothiazolyl- (6CI,7CI,8CI);2-(2-Benzothiazolyl)phenol;2-(2'-Hydroxyphenyl)-2-benzothiazole;2-(2'-Hydroxyphenyl)benzothiazole;2-(Benzo[d]thiazol-2-yl)phenol;2-(o-Hydroxyphenyl)benzothiazole;HBT;NSC 5051;NSC 58548;
  • PSA 61.36000
  • LogP 3.66890

Synthetic route

salicylaldehyde
90-02-8

salicylaldehyde

2-amino-benzenethiol
137-07-5

2-amino-benzenethiol

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
With cadmium sulphide In methanol at 20℃; for 0.333333h; Catalytic behavior; Irradiation;98%
With 3,6-di(2'-pyridyl)-1,2,4,5-tetrazine In ethanol at 20℃; for 0.5h; Irradiation; Green chemistry;98%
With manganese doped CdS nanoparticles In water at 90℃; for 1.5h; chemoselective reaction;98%
2-methyl-benzyl alcohol
89-95-2

2-methyl-benzyl alcohol

2-amino-benzenethiol
137-07-5

2-amino-benzenethiol

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
With 1-pentyl-3-methylimidazolium bromide for 0.0583333h; microwave irradiation;95%
With iodine In N,N-dimethyl-formamide at 100℃; for 0.5h;81%
With iodine at 20℃; for 0.25h;80%
With zirconium(IV) oxychloride for 0.0666667h; Irradiation; microwave;76%
With silica gel for 0.0833333h; microwave irradiation;87 % Chromat.
2-amino-benzenethiol
137-07-5

2-amino-benzenethiol

salicylic acid
69-72-7

salicylic acid

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
Stage #1: 2-amino-benzenethiol; salicylic acid In toluene at 80℃; for 1h;
Stage #2: With phosphorus trichloride In toluene at 40 - 100℃; for 6h;
92%
Stage #1: 2-amino-benzenethiol; salicylic acid In toluene at 100℃; for 1h;
Stage #2: With phosphorus trichloride In toluene at 40 - 60℃; for 6.5h;
92%
With polyphosphoric acid at 180℃; for 3h;85%
salicylaldehyde
90-02-8

salicylaldehyde

2-Aminophenyl disulfide
1141-88-4

2-Aminophenyl disulfide

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
With oxygen In water for 4h; Catalytic behavior; Reflux; Green chemistry;91%
With toluene-4-sulfonic acid In PEG-200/400 for 0.166667h; Microwave irradiation;89%
In glycerol at 175℃; for 0.75h; Green chemistry;81.1%
2-(2-hydroxyphenyl)benzothiazoline
7361-94-6

2-(2-hydroxyphenyl)benzothiazoline

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
With sodium hypochlorite In ethanol at 20℃; for 1h;90%
With Dowex 50W In water at 90℃; for 25h;70%
With (2,3,4,5,6-pentafluorophenyl)ammonium triflate; oxygen In water for 10h; Reflux;70%
With sodium cyanide In N,N-dimethyl-formamide810 mg
for 10h; UV-irradiation;
2-iodophenylamine
615-43-0

2-iodophenylamine

salicylaldehyde
90-02-8

salicylaldehyde

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
With 1,10-Phenanthroline; copper(II) choride dihydrate; potassium carbonate; sulfur In water at 100℃; for 24h;90%
4-chloro-2,2-dimethyl-2H-benzo[e][1,3]oxazine
74405-07-5

4-chloro-2,2-dimethyl-2H-benzo[e][1,3]oxazine

2-amino-benzenethiol
137-07-5

2-amino-benzenethiol

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
In acetonitrile for 1h; Heating;89%
2-(trifluoromethyl)phenol
444-30-4

2-(trifluoromethyl)phenol

2-amino-benzenethiol
137-07-5

2-amino-benzenethiol

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
With sodium hydroxide In water at 80℃; for 2h;88%
With sodium hydroxide at 90℃; for 1h; Inert atmosphere;86%
With sodium hydroxide at 90℃; for 1h; Inert atmosphere; Schlenk technique;80%
With sodium hydroxide
2-hydroxy-N-(2-iodophenyl)benzamide
1039984-47-8

2-hydroxy-N-(2-iodophenyl)benzamide

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
Stage #1: 2-hydroxy-N-(2-iodophenyl)benzamide With copper(l) iodide; sodiumsulfide nonahydrate In N,N-dimethyl-formamide at 80℃; for 12h;
Stage #2: With hydrogenchloride In N,N-dimethyl-formamide at 20℃;
85%
1,3-Benzothiazole
95-16-9

1,3-Benzothiazole

N-(phenoxy)acetamide
5661-50-7

N-(phenoxy)acetamide

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; cesium acetate; silver(I) triflimide In dimethyl sulfoxide at 85℃; for 30h; Inert atmosphere;85%
N-(2-allyloxybenzylidene)-2-phenylthiobenzenamine
1354644-30-6

N-(2-allyloxybenzylidene)-2-phenylthiobenzenamine

A

biphenyl
92-52-4

biphenyl

B

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

C

2-Allylphenol
1745-81-9

2-Allylphenol

Conditions
ConditionsYield
at 150 - 650℃; under 0.013 Torr; for 0.25h; Pyrolysis;A 2%
B 84%
C 9%
2-Phenylbenzothiazole
883-93-2

2-Phenylbenzothiazole

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
With sodium persulfate; palladium diacetate In 1,4-dioxane at 80℃; for 12h; Reagent/catalyst; Inert atmosphere;83%
With Bromotrichloromethane; (4s,6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile; oxygen; palladium diacetate In cyclohexane; 1,2-dichloro-ethane at 20℃; for 24h; Solvent; Irradiation;61%
With [bis(acetoxy)iodo]benzene; palladium diacetate; trifluoroacetic acid at 110℃; for 6h; Catalytic behavior; Reagent/catalyst; Solvent; Time; Concentration; regioselective reaction;
2-Phenylbenzothiazole
883-93-2

2-Phenylbenzothiazole

acetic acid
64-19-7

acetic acid

A

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

B

2-(benzo[d]thiazol-2-yl)-3-hydroxyphenyl acetate
1422963-57-2

2-(benzo[d]thiazol-2-yl)-3-hydroxyphenyl acetate

Conditions
ConditionsYield
With [bis(acetoxy)iodo]benzene; palladium diacetate at 110℃; for 5h; Catalytic behavior; Concentration; Reagent/catalyst; Time; Overall yield = 90 %; regioselective reaction;A 81%
B 9%
C16H11NO4S

C16H11NO4S

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
With sodium phosphate In dimethyl sulfoxide at 20℃; for 24h;81%
4-(2-benzothiazol-2-yl-phenoxymethyl)-benzoic acid methyl ester

4-(2-benzothiazol-2-yl-phenoxymethyl)-benzoic acid methyl ester

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
With magnesium In tetrahydrofuran; methanol at 20℃; for 10h;77%
2-Phenylbenzothiazole
883-93-2

2-Phenylbenzothiazole

acetic acid
64-19-7

acetic acid

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
With (4s,6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile; oxygen; palladium diacetate; potassium trifluoroacetate In N,N-dimethyl-formamide at 70℃; for 24h; Catalytic behavior; Reagent/catalyst; Solvent; Temperature; Irradiation;75%
(2-hydroxyphenyl)oxoacetic acid
17392-16-4

(2-hydroxyphenyl)oxoacetic acid

2-amino-benzenethiol
137-07-5

2-amino-benzenethiol

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
With dihydrogen peroxide In 1,4-dioxane; water at 20℃; for 8h; Irradiation;73%
1,3-Benzothiazole
95-16-9

1,3-Benzothiazole

salicylaldehyde
90-02-8

salicylaldehyde

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
With tert.-butylhydroperoxide; N-chloro-succinimide In decane; dimethyl sulfoxide at 120℃; for 12h; Inert atmosphere;71%
With tert.-butylhydroperoxide; N-chloro-succinimide In decane; dimethyl sulfoxide at 120℃; for 10h; Schlenk technique;71%
With di-tert-butyl peroxide In 1-methyl-pyrrolidin-2-one at 100℃; for 3h;47%
salicylic acid
69-72-7

salicylic acid

2-Aminophenyl disulfide
1141-88-4

2-Aminophenyl disulfide

A

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

B

C20H15NO4S

C20H15NO4S

Conditions
ConditionsYield
Stage #1: salicylic acid; 2-Aminophenyl disulfide In toluene at 70℃; for 2.5h; Inert atmosphere;
Stage #2: With phosphorus trichloride In toluene at 30 - 100℃; Inert atmosphere;
A 66%
B n/a
salicylaldehyde
90-02-8

salicylaldehyde

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

2-amino-benzenethiol
137-07-5

2-amino-benzenethiol

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
In butan-1-ol for 7h; Reflux;65%
With benzoic acid In butan-1-ol at 110℃; for 8h;62%
salicylaldehyde
90-02-8

salicylaldehyde

2-Chloronitrobenzene
88-73-3

2-Chloronitrobenzene

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
With 4-methyl-morpholine; sulfur at 130℃; for 16h; Sealed tube; Inert atmosphere;62%
2-hydroxybenzyl bromide
58402-38-3

2-hydroxybenzyl bromide

2-amino-benzenethiol
137-07-5

2-amino-benzenethiol

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
In acetonitrile Irradiation; chemoselective reaction;61%
C20H13NO2S2

C20H13NO2S2

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
With gold(III) chloride In methanol; water57%
1,3-Benzothiazole
95-16-9

1,3-Benzothiazole

2-Iodophenol
533-58-4

2-Iodophenol

A

4-(2-hydroxyphenyl)-4,7-dihydrobenzothiazole

4-(2-hydroxyphenyl)-4,7-dihydrobenzothiazole

B

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
With 2,2'-azobis(isobutyronitrile); diphenyl diselenide; tri-n-butyl-tin hydride In benzene for 1h; Heating;A 7%
B 19%
salicylanilide
87-17-2

salicylanilide

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
With sulfur
2-aminobenzenethiol hydrochloride
3292-42-0

2-aminobenzenethiol hydrochloride

salicylaldehyde
90-02-8

salicylaldehyde

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
With ethanol
2-amino-benzenethiol
137-07-5

2-amino-benzenethiol

salicylamide
65-45-2

salicylamide

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
at 240 - 250℃;
benzothiazole 3-oxide
27655-26-1

benzothiazole 3-oxide

benzenedizolium-2-carboxylate
1608-42-0

benzenedizolium-2-carboxylate

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
In tert-butyl alcohol
N-phenylsalicylaldimine
779-84-0

N-phenylsalicylaldimine

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Conditions
ConditionsYield
With sulfur Heating;
scandium isopropoxide

scandium isopropoxide

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Sc(III)-tris-2-(2-benzthiazol-2-yl)phenolate
1190879-78-7

Sc(III)-tris-2-(2-benzthiazol-2-yl)phenolate

Conditions
ConditionsYield
In acetonitrile at 20℃; Inert atmosphere; Reflux;100%
beryllium sulfate

beryllium sulfate

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Be(2-(2'-oxyphenyl)benzothiazole)2]
236753-06-3

Be(2-(2'-oxyphenyl)benzothiazole)2]

Conditions
ConditionsYield
With sodium hydroxide In methanol at 20℃; Inert atmosphere;100%
2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

(4-hydroxy-phenyl)triphenylphosphonium bromide
22883-70-1

(4-hydroxy-phenyl)triphenylphosphonium bromide

C24H20OP(1+)*C13H8NOS(1-)

C24H20OP(1+)*C13H8NOS(1-)

Conditions
ConditionsYield
Stage #1: 2-(benzothiazol-2-yl)phenol With sodium methylate In methanol at 20℃; for 2h;
Stage #2: (4-hydroxy-phenyl)triphenylphosphonium bromide In methanol at 20℃; for 2h;
99%
2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

hafnium tetrachloride
13499-05-3

hafnium tetrachloride

tetrakis(2-(2-hydroxyphenyl)benzothiazole)hafnium
1210945-34-8

tetrakis(2-(2-hydroxyphenyl)benzothiazole)hafnium

Conditions
ConditionsYield
With piperidine In ethanol at 20℃; Inert atmosphere; Reflux;98%
2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

4-Nitrophthalonitrile
31643-49-9

4-Nitrophthalonitrile

4-(2-(benzo[d]thiazol-2-yl)phenoxy)phthalonitrile
1578263-21-4

4-(2-(benzo[d]thiazol-2-yl)phenoxy)phthalonitrile

Conditions
ConditionsYield
Stage #1: 2-(benzothiazol-2-yl)phenol; 4-Nitrophthalonitrile In N,N-dimethyl-formamide at 50℃; for 0.166667h; Inert atmosphere;
Stage #2: With potassium carbonate In N,N-dimethyl-formamide at 50℃; for 122h; Inert atmosphere;
97%
bis(tert-butylimido)bis(tert-butylamido)tungsten

bis(tert-butylimido)bis(tert-butylamido)tungsten

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

bis(tert-butylimido)bis(2-benzothiazolyl-2-phenolato)tungsten

bis(tert-butylimido)bis(2-benzothiazolyl-2-phenolato)tungsten

Conditions
ConditionsYield
In toluene chelate ligand is added to soln. of the W compd. in toluene under argon, soln. is refluxed for 2 min, cooled to room temp.; concd. (vac.), addn. of hexane, cooling to -20°C, filtn., washing (hexane), drying (vac.); elem. anal.;96%
2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

allyl bromide
106-95-6

allyl bromide

2-(2-(allyloxy)phenyl)benzo[d]thiazole

2-(2-(allyloxy)phenyl)benzo[d]thiazole

Conditions
ConditionsYield
With potassium carbonate In acetone for 2h; Reflux;96%
With potassium carbonate In tetrahydrofuran for 3h; Reflux;50%
2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

bis(μ-hydroxo)bis(tris(3,5-dimethylpyrazolyl)borate)dinickel(II)

bis(μ-hydroxo)bis(tris(3,5-dimethylpyrazolyl)borate)dinickel(II)

[Ni(hydrotris(3,5-dimethylpyrazolyl)borate)(2-(2'-hydroxylphenyl)benzothiazole(-1H))]
1610351-76-2

[Ni(hydrotris(3,5-dimethylpyrazolyl)borate)(2-(2'-hydroxylphenyl)benzothiazole(-1H))]

Conditions
ConditionsYield
In chloroform94%
2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

tris(bistrimethylsilylamine)scandium(III)

tris(bistrimethylsilylamine)scandium(III)

Sc(III)-tris-2-(2-benzthiazol-2-yl)phenolate
1190879-78-7

Sc(III)-tris-2-(2-benzthiazol-2-yl)phenolate

Conditions
ConditionsYield
In 1,2-dimethoxyethane soln. of benzothiazole in DME was added to soln. of scandium complex in DME, stirred for 30 min at room temp.; evapd. in vac., washed with toluene, dried in vac., elem. anal.;93%
tris(bis(trimethylsilyl)amido)samarium(III)

tris(bis(trimethylsilyl)amido)samarium(III)

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

tetra(2-(2-hydroxyphenyl)-benzothiazolato)di(μ-2-(2-hydroxyphenyl)benzothiazolato)Sm2
1422197-95-2

tetra(2-(2-hydroxyphenyl)-benzothiazolato)di(μ-2-(2-hydroxyphenyl)benzothiazolato)Sm2

Conditions
ConditionsYield
In Dimethyl ether at 20℃; for 0.5h;93%
2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

diphenylborinic anhydride

diphenylborinic anhydride

2-(2-((diphenylboryl)oxy)phenyl)benzo[d]thiazole

2-(2-((diphenylboryl)oxy)phenyl)benzo[d]thiazole

Conditions
ConditionsYield
In tetrahydrofuran for 2h; Inert atmosphere; Reflux;92%
2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

16-oxo-1-oxa-4-azacyclohexadecane-4-carbonyl chloride

16-oxo-1-oxa-4-azacyclohexadecane-4-carbonyl chloride

2-(benzo[d]thiazol-2-yl)phenyl 16-oxo-1-oxa-4-azacyclohexadecane-4-carboxylate

2-(benzo[d]thiazol-2-yl)phenyl 16-oxo-1-oxa-4-azacyclohexadecane-4-carboxylate

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane at 20℃; Cooling with ice;92%
tris[N,N-bis(trimethylsilyl)amide]gadolinium(III)

tris[N,N-bis(trimethylsilyl)amide]gadolinium(III)

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

tetra(2-(2-hydroxyphenyl)-benzothiazolato)di(μ-2-(2-hydroxyphenyl)benzothiazolato)Gd2
1422198-04-6

tetra(2-(2-hydroxyphenyl)-benzothiazolato)di(μ-2-(2-hydroxyphenyl)benzothiazolato)Gd2

Conditions
ConditionsYield
In Dimethyl ether at 20℃; for 0.5h;91%
2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

ethoxydiphenylborane
43185-52-0

ethoxydiphenylborane

2-(2-((diphenylboryl)oxy)phenyl)benzo[d]thiazole

2-(2-((diphenylboryl)oxy)phenyl)benzo[d]thiazole

Conditions
ConditionsYield
In ethanol at 50℃; for 3h; Inert atmosphere;91%
tetraphenylarsonium tetrachlorooxorhenate(V)
14853-14-6

tetraphenylarsonium tetrachlorooxorhenate(V)

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

As(C6H5)4{ReOCl3(hbt)}
116887-58-2

As(C6H5)4{ReOCl3(hbt)}

Conditions
ConditionsYield
In isopropyl alcohol mixing of a 2-fold molar excess of 2-(2-hydroxyphenyl)benzothiazole with a soln. of As(C6H5)4(ReOCl4) in isopropanol (25°C) to form immediately a ppt.; filtration, washing (isopropanol, diethyl ether), recrystn. (CH2Cl2, ethanol); elem. anal.;90%
{As(C6H5)4}(1+)*{(99)TcOBr4}(1-)={As(C6H5)4}{(99)TcOBr4}
116887-56-0

{As(C6H5)4}(1+)*{(99)TcOBr4}(1-)={As(C6H5)4}{(99)TcOBr4}

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

As(C6H5)4{TcOBr3(hbt)}
116887-54-8

As(C6H5)4{TcOBr3(hbt)}

Conditions
ConditionsYield
In isopropyl alcohol mixing of a 2-fold molar excess of 2-(2-hydroxyphenyl)benzothiazole with a soln. of As(C6H5)4(TcOBr4) in isopropanol (25°C) to form immediately a ppt.; filtration, washing (isopropanol, diethyl ether), recrystn. (CH2Cl2, ethanol); elem. anal.;90%
{As(C6H5)4}(1+)*{ReOBr4}(1-)={As(C6H5)4}{ReOBr4}
14853-12-4

{As(C6H5)4}(1+)*{ReOBr4}(1-)={As(C6H5)4}{ReOBr4}

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

As(C6H5)4{ReOBr3(hbt)}
116887-60-6

As(C6H5)4{ReOBr3(hbt)}

Conditions
ConditionsYield
In isopropyl alcohol mixing of a 2-fold molar excess of 2-(2-hydroxyphenyl)benzothiazole with a soln. of As(C6H5)4(ReOBr4) in isopropanol (25°C) to form immediately a ppt.; filtration, washing (isopropanol, diethyl ether), recrystn. (CH2Cl2, ethanol); elem. anal.;90%
As(C6H5)4(1+)*(99)Tc(O)Cl4(1-) = [As(C6H5)4][(99)Tc(O)Cl4]
97101-52-5

As(C6H5)4(1+)*(99)Tc(O)Cl4(1-) = [As(C6H5)4][(99)Tc(O)Cl4]

2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

tetraphenylarsonium oxotrichloro{2-(2-hydroxyphenyl)benzothiazolato}technetate(V)
116887-52-6

tetraphenylarsonium oxotrichloro{2-(2-hydroxyphenyl)benzothiazolato}technetate(V)

Conditions
ConditionsYield
In isopropyl alcohol mixing of a 2-fold molar excess of 2-(2-hydroxyphenyl)benzothiazole with a soln. of As(C6H5)4(TcOCl4) in isopropanol (25°C) to form immediately a ppt.; filtration, washing (isopropanol, diethyl ether), recrystn. (CH2Cl2, ethanol); elem. anal.;90%
2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

1-(6-(chloromethyl)pyridine-2-yl)-N,N-bis(pyridine-2-ylmethyl)methaneamine
279216-12-5

1-(6-(chloromethyl)pyridine-2-yl)-N,N-bis(pyridine-2-ylmethyl)methaneamine

C32H27N5OS
1414968-71-0

C32H27N5OS

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 90℃;90%
2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

trifluoroacetic acid
76-05-1

trifluoroacetic acid

5-(benzo[d]thiazol-2-yl)-4-hydroxyisophthalaldehyde
1428114-89-9

5-(benzo[d]thiazol-2-yl)-4-hydroxyisophthalaldehyde

Conditions
ConditionsYield
With hexamethylenetetramine Reflux;90%
With hexamethylenetetramine for 0.166667h; Reflux;90%
2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

Allyl chloroformate
2937-50-0

Allyl chloroformate

allyl (2-(benzo[d]thiazol-2-yl)phenyl) carbonate

allyl (2-(benzo[d]thiazol-2-yl)phenyl) carbonate

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 0 - 20℃; for 2.5h;90%
2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

chloroacetyl chloride
79-04-9

chloroacetyl chloride

chloro-acetic acid 2-benzothiazol-2-yl-phenyl ester

chloro-acetic acid 2-benzothiazol-2-yl-phenyl ester

Conditions
ConditionsYield
Stage #1: 2-(benzothiazol-2-yl)phenol With potassium carbonate In tetrahydrofuran for 0.5h;
Stage #2: chloroacetyl chloride In tetrahydrofuran at 20 - 50℃; for 12h; Reagent/catalyst; Solvent; Temperature;
90%
2-(benzothiazol-2-yl)phenol
3411-95-8

2-(benzothiazol-2-yl)phenol

12-oxo-1-oxa-4-azacyclododecane-4-carbonyl chloride

12-oxo-1-oxa-4-azacyclododecane-4-carbonyl chloride

2-(benzo[d]thiazol-2-yl)phenyl 12-oxo-1-oxa-4-azacyclododecane-4-carboxylate

2-(benzo[d]thiazol-2-yl)phenyl 12-oxo-1-oxa-4-azacyclododecane-4-carboxylate

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane at 20℃; Cooling with ice;90%

2-(2-Hydroxyphenyl)benzothiazole Chemical Properties

IUPAC Name: 6-(3H-1,3-benzothiazol-2-ylidene)cyclohexa-2,4-dien-1-one
The MF of 2-(2-Hydroxyphenyl)benzothiazole(3411-95-8): C13H9NOS
The MW of 2-(2-Hydroxyphenyl)benzothiazole(3411-95-8): 227.28
EINECS: 222-299-9
mp: 128-132 °C(lit.)
Density: 1.365 g/cm3 
Flash Point: 190.8 °C 
Boiling Point: 391.8 °C at 760 mmHg 
Index of Refraction: 1.714 
Appearance: Off-white crystals.
Solubility in water: Insoluble
Categories: Building Blocks;Heterocyclic Building Blocks;Thiazoles
Synonyms: 2-(2-BENZOTHIAZOLYL)PHENOL;2-(2-HYDROXYPHENYL)BENZOTHIAZOLE;2-(BENZO[D]THIAZOL-2-YL)PHENOL;2-(O-HYDROXYPHENYL)BENZOTHIAZOLE;TIMTEC-BB SBB005787;O-(2-BENZOTHIAZOLYL)PHENOL;2-(1,3-Benzothiazol-2-yl)phenol;2-(2-benzothiazolyl)-pheno
The Structure of 2-(2-Hydroxyphenyl)benzothiazole(3411-95-8):

2-(2-Hydroxyphenyl)benzothiazole Safety Profile

Hazard Codes: Xi
Risk Statements: 36/37/38
36/37/38:  Irritating to eyes, respiratory system and skin
Safety Statements: 26-37/39
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
37/39:  Wear suitable gloves and eye/face protection
WGK Germany: 3
RTECS: SJ7360000
Hazard Note: Irritant

2-(2-Hydroxyphenyl)benzothiazole Specification

1. First Aid Measures
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Eyes:
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
2. Handling and Storage
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
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