2,3-Difluoroaniline supplier

Name
2,3-Difluoroaniline
EINECS 224-847-2
CAS No. 4519-40-8
Article Data7
CAS DataBase
Density 1.289 g/cm³
Solubility
Melting Point
Formula C₆H₅F₂N
Boiling Point 176.6 °C at 760 mmHg
Molecular Weight 129.109
Flash Point 71.1 °C
Transport Information UN 2941
Appearance clear light orange liquid
Safety 26-27-28-36/37/39
Risk Codes 20/21/22-36/37/38
Molecular Structure
Hazard Symbols Xn, Xi
Synonyms Aniline,2,3-difluoro- (7CI,8CI);2,3-Difluorophenylamine;Benzenamine,2,3-difluoro-;
PSA 26.02000
LogP 2.12820

Synthetic route

: 2,3-dibromo-5,6-difluoroaniline

: 4519-40-8
2,3-difluoroanilline

Conditions

Conditions	Yield
With palladium 10% on activated carbon; hydrogen; triethylamine In methanol at 50℃; for 3h;	98%

: 1481-57-8
1,2-dibromo-4,5-difluoro-3-nitrobenzene

: 4519-40-8
2,3-difluoroanilline

Conditions

Conditions	Yield
With palladium 10% on activated carbon; hydrogen; triethylamine In methanol at 50℃; for 2.5h; Temperature;	93%

: 1-(2,3-difluorophenyl)pyrrolidine-2,5-dione

: 4519-40-8
2,3-difluoroanilline

Conditions

Conditions	Yield
With hydrogenchloride In water for 1h; Reflux;	89.1%

: 1-(6-amino-2,3-difluorophenyl)pyrrolidine-2,5-dione

: 4519-40-8
2,3-difluoroanilline

Conditions

Conditions	Yield
Stage #1: 1-(6-amino-2,3-difluorophenyl)pyrrolidine-2,5-dione With sulfuric acid; acetic acid; sodium nitrite at 5℃; for 0.5h; Stage #2: With ethanol; zinc for 1.5h; Reflux;	83.6%
Multi-step reaction with 2 steps 1.1: sodium nitrite; sulfuric acid; acetic acid / 0.5 h / 5 °C 1.2: 1 h / 50 °C 2.1: hydrogenchloride / water / 1 h / Reflux View Scheme

: 87-61-6
1,2,3-trichlorobenzene

A: 4519-40-8
2,3-difluoroanilline

B: 5509-65-9
2,6-difluoroaniline

Conditions

Conditions	Yield
With ammonium hydroxide; cesium fluoride; copper(I) oxide 1.) N,N'-dimethylethyleneurea, 250 deg C (bomb), 12 h, 2.) 170 deg C (bomb), 24 h; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given;
With ammonium hydroxide; cesium fluoride; copper(I) oxide 1.) N,N'-dimethylethyleneurea, 250 deg C (bomb), 12 h, 2.) 160 deg C (bomb), 24 h; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given;

: difluorotrichloronitrobenzene

: 67-63-0
isopropyl alcohol

: 4519-40-8
2,3-difluoroanilline

Conditions

Conditions	Yield
With hydrogen; sodium formate; palladium on charcoal

: 36556-39-5
difluorodichlorobenzene

: 1435-43-4
1-chloro-3,5-difluorobenzene

: 136272-32-7
3,4,5-trichloro-2,6-difluoronitrobenzene

: 136272-33-8
1,2,4-trichloro-3,5-difluoronitrobenzene

: 4519-40-8
2,3-difluoroanilline

Conditions

Conditions	Yield
With sulfuric acid; nitric acid; sodium acetate; chlorine; aluminium trichloride; palladium on charcoal In methanol; dichloromethane

...Expand

: 367-11-3
ortho-difluorobenzene

: 4519-40-8
2,3-difluoroanilline

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: iron; bromine / 4.83 h / 20 - 50 °C 2: sulfuric acid; nitric acid / water / 1.5 h / 20 - 35 °C 3: palladium 10% on activated carbon; hydrogen; triethylamine / methanol / 2.5 h / 50 °C View Scheme
Multi-step reaction with 4 steps 1: iron; bromine / 4.83 h / 20 - 50 °C 2: sulfuric acid; nitric acid / water / 1.5 h / 20 - 35 °C 3: iron; calcium chloride; ethanol; water / 3.2 h / 55 °C 4: palladium 10% on activated carbon; hydrogen; triethylamine / methanol / 3 h / 50 °C View Scheme

: 64695-78-9
1,2-difluoro-4,5-dibromobenzene

: 4519-40-8
2,3-difluoroanilline

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: sulfuric acid; nitric acid / water / 1.5 h / 20 - 35 °C 2: palladium 10% on activated carbon; hydrogen; triethylamine / methanol / 2.5 h / 50 °C View Scheme
Multi-step reaction with 3 steps 1: sulfuric acid; nitric acid / water / 1.5 h / 20 - 35 °C 2: iron; calcium chloride; ethanol; water / 3.2 h / 55 °C 3: palladium 10% on activated carbon; hydrogen; triethylamine / methanol / 3 h / 50 °C View Scheme

: 1,2-dichloro-4,5-difluoro-3-nitrobenzene

A: 4519-40-8
2,3-difluoroanilline

B: 2,3-dichloro-5,6-difluoroaniline

Conditions

Conditions	Yield
With palladium 10% on activated carbon; hydrogen; triethylamine In methanol at 45℃; for 4.2h; Temperature;

: 367-11-3
ortho-difluorobenzene

A: 4519-40-8
2,3-difluoroanilline

B: 2,3-dichloro-5,6-difluoroaniline

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: iron(III) chloride; chlorine / 9 h / 48 - 54 °C 2: sulfuric acid; nitric acid / water / 7 h / 20 - 26 °C 3: palladium 10% on activated carbon; hydrogen; triethylamine / methanol / 4.2 h / 45 °C View Scheme

: 1,2-dichloro-4,5-difluorobenzene

A: 4519-40-8
2,3-difluoroanilline

B: 2,3-dichloro-5,6-difluoroaniline

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: sulfuric acid; nitric acid / water / 7 h / 20 - 26 °C 2: palladium 10% on activated carbon; hydrogen; triethylamine / methanol / 4.2 h / 45 °C View Scheme

: 771-69-7
2,3,4-trifluoronitrobenzene

: 4519-40-8
2,3-difluoroanilline

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: potassium carbonate / N,N-dimethyl-formamide / 6 h / 20 °C 2.1: hydrogen; palladium 10% on activated carbon / methanol / 4 h / 20 °C / Inert atmosphere 3.1: sodium nitrite; sulfuric acid; acetic acid / 0.5 h / 5 °C 3.2: 1.5 h / Reflux View Scheme
Multi-step reaction with 4 steps 1.1: ammonium hydroxide / ethanol / 8 h / 20 °C 2.1: toluene-4-sulfonic acid / 5,5-dimethyl-1,3-cyclohexadiene / 7 h / Dean-Stark; Reflux 3.1: hydrogen; palladium 10% on activated carbon / methanol / 4 h / 20 °C / Inert atmosphere 4.1: sodium nitrite; sulfuric acid; acetic acid / 0.5 h / 5 °C 4.2: 1.5 h / Reflux View Scheme
Multi-step reaction with 4 steps 1.1: potassium carbonate / N,N-dimethyl-formamide / 6 h / 20 °C 2.1: hydrogen; palladium 10% on activated carbon / methanol / 4 h / 20 °C / Inert atmosphere 3.1: sodium nitrite; sulfuric acid; acetic acid / 0.5 h / 5 °C 3.2: 1 h / 50 °C 4.1: hydrogenchloride / water / 1 h / Reflux View Scheme
Multi-step reaction with 5 steps 1.1: ammonium hydroxide / ethanol / 8 h / 20 °C 2.1: toluene-4-sulfonic acid / 5,5-dimethyl-1,3-cyclohexadiene / 7 h / Dean-Stark; Reflux 3.1: hydrogen; palladium 10% on activated carbon / methanol / 4 h / 20 °C / Inert atmosphere 4.1: sodium nitrite; sulfuric acid; acetic acid / 0.5 h / 5 °C 4.2: 1 h / 50 °C 5.1: hydrogenchloride / water / 1 h / Reflux View Scheme

: 211693-73-1
2-amino-3,4-difluoronitro-benzene

: 4519-40-8
2,3-difluoroanilline

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: toluene-4-sulfonic acid / 5,5-dimethyl-1,3-cyclohexadiene / 7 h / Dean-Stark; Reflux 2.1: hydrogen; palladium 10% on activated carbon / methanol / 4 h / 20 °C / Inert atmosphere 3.1: sodium nitrite; sulfuric acid; acetic acid / 0.5 h / 5 °C 3.2: 1.5 h / Reflux View Scheme
Multi-step reaction with 4 steps 1.1: toluene-4-sulfonic acid / 5,5-dimethyl-1,3-cyclohexadiene / 7 h / Dean-Stark; Reflux 2.1: hydrogen; palladium 10% on activated carbon / methanol / 4 h / 20 °C / Inert atmosphere 3.1: sodium nitrite; sulfuric acid; acetic acid / 0.5 h / 5 °C 3.2: 1 h / 50 °C 4.1: hydrogenchloride / water / 1 h / Reflux View Scheme

: 1-(2,3-difluoro-6-nitrophenyl)pyrrolidine-2,5-dione

: 4519-40-8
2,3-difluoroanilline

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: hydrogen; palladium 10% on activated carbon / methanol / 4 h / 20 °C / Inert atmosphere 2.1: sodium nitrite; sulfuric acid; acetic acid / 0.5 h / 5 °C 2.2: 1.5 h / Reflux View Scheme
Multi-step reaction with 3 steps 1.1: hydrogen; palladium 10% on activated carbon / methanol / 4 h / 20 °C / Inert atmosphere 2.1: sodium nitrite; sulfuric acid; acetic acid / 0.5 h / 5 °C 2.2: 1 h / 50 °C 3.1: hydrogenchloride / water / 1 h / Reflux View Scheme

: 4519-40-8
2,3-difluoroanilline

: 140-89-6
potassium ethyl xanthogenate

: 154327-29-4
2-mercapto-7-fluorobenzothiazole

Conditions

Conditions	Yield
In N,N-dimethyl-formamide for 4h; Inert atmosphere; Heating;	100%
In N,N-dimethyl-formamide at 100℃; for 4h; Inert atmosphere;	100%
In N,N-dimethyl-formamide at 160℃; for 4h;	89%

: 722544-24-3
2-(3-((7-(benzyloxy)quinazolin-4-yl)amino)-1H-pyrazol-5-yl)acetic acid

: 4519-40-8
2,3-difluoroanilline

: 722544-25-4
2-(3-{[7-(benzyloxy)quinazolin-4-yl]amino}-1H-pyrazol-5-yl)-N-(2,3-difluorophenyl)acetamide

Conditions

Conditions	Yield
With pyridine; trichlorophosphate at 0 - 20℃; for 2h;	100%

: 4519-40-8
2,3-difluoroanilline

: 112279-72-8
4-bromo-2,3-difluoro-aniline

Conditions

Conditions	Yield
With N-Bromosuccinimide In N,N-dimethyl-formamide for 1h; Cooling with ice;	100%
With N-Bromosuccinimide In N,N-dimethyl-formamide at 0℃; for 1h;	97%
With N-Bromosuccinimide In acetonitrile at 35℃; for 2h;	68%

: 4519-40-8
2,3-difluoroanilline

: 210532-24-4
2,3-difluorobenzenesulphonyl chloride

Conditions

Conditions	Yield
Stage #1: 2,3-difluoroanilline With hydrogenchloride; sodium nitrite In water at -5 - 0℃; for 0.166667h; Ice/NaCl; Stage #2: With thionyl chloride; copper(l) chloride In water at -5℃; for 0.5h;	98%
With hydrogenchloride; acetic acid; mercury; sodium nitrite; copper(I) chloride In water
Stage #1: 2,3-difluoroanilline With hydrogenchloride; sodium nitrite In water at -10℃; for 0.666667h; Stage #2: With hydrogenchloride; sulfur dioxide; copper(l) chloride In water; acetic acid at 0℃;
Stage #1: 2,3-difluoroanilline With hydrogenchloride; acetic acid; sodium nitrite In water at -5℃; Stage #2: With sulfur dioxide; copper(l) chloride In water for 0.25h; Cooling with ice;
Stage #1: 2,3-difluoroanilline With hydrogenchloride; sodium nitrite In water at -10℃; for 0.666667h; Stage #2: With sulfur dioxide; copper(l) chloride In water; acetic acid at 0℃;

: 845868-07-7
1-methanesulfonyl-1H-pyrrole-2,4-dicarboxylic acid 2-methyl ester

: 4519-40-8
2,3-difluoroanilline

: 845868-08-8
4-(2,3-difluoro-phenylcarbamoyl)-1-methanesulfonyl-1H-pyrrole-2-carboxylic acid methyl ester

Conditions

Conditions	Yield
Stage #1: 1-methanesulfonyl-1H-pyrrole-2,4-dicarboxylic acid 2-methyl ester With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 20℃; for 1h; Stage #2: 2,3-difluoroanilline With triethylamine In dichloromethane for 1h;	98%

: 50329-91-4
4-chloro-3-formylcoumarin

: 4519-40-8
2,3-difluoroanilline

: 1394232-19-9
7,8-difluoro-4-(2-hydroxyphenyl)quinoline-3-carboxylic acid

Conditions

Conditions	Yield
With sulfuric acid In methanol at 20℃; for 0.0833333h;	98%

: 4519-40-8
2,3-difluoroanilline

: 821-48-7
bis-(2-chloroethyl)amine hydrochloride

: 1-(2,3-difluorophenyl)piperazine hydrochloride

Conditions

Conditions	Yield
In diethylene glycol dimethyl ether at 130℃; for 15h;	97.9%

: 4519-40-8
2,3-difluoroanilline

: 6645-69-8
2-(4-nitro-1H-pyrazol-1-yl)acetic acid

: 786681-72-9
N-(2,3-difluorophenyl)-2-(4-nitro-1H-pyrazol-1-yl)acetamide

Conditions

Conditions	Yield
With pyridine; trichlorophosphate In dichloromethane for 2h;	97%

: 4519-40-8
2,3-difluoroanilline

: 140-89-6
potassium ethyl xanthogenate

: 7-fluoro-1,3-benzothiazole-2(3H)-thione

Conditions

Conditions	Yield
In N,N-dimethyl-formamide for 2h; Heating;	96%
In 1-methyl-pyrrolidin-2-one at 120℃;

: 28563-38-4
ethylxanthogenate

: 4519-40-8
2,3-difluoroanilline

: 154327-29-4
2-mercapto-7-fluorobenzothiazole

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 120℃; for 2h;	96%

: 4519-40-8
2,3-difluoroanilline

: 5329-14-6
aminosulfonic acid

: 79-10-7
acrylic acid

: 94977-52-3
2,4-Difluorocinnamic acid

Conditions

Conditions	Yield
With sulfuric acid; sodium nitrite; palladium diacetate In water	95%

...Expand

: 50329-91-4
4-chloro-3-formylcoumarin

: 4519-40-8
2,3-difluoroanilline

: 1357063-68-3
10,11-difluoro-6H-chromeno[4,3-b]quinolin-6-one

Conditions

Conditions	Yield
In ethanol at 20℃; for 0.25h; ultrasound irradiation;	94%
In methanol at 20℃; for 0.15h; ultrasound irradiation;	92%
With Amberlyst-15 In ethanol for 2h; Reflux; Inert atmosphere;	78%

: 4519-40-8
2,3-difluoroanilline

: (3RS,4SR)-1-allyloxy-4-(4-methylphenyl)-2-oxo-pyrrolidine-3-carboxylic acid

: (3RS,4RS)-1-allyloxy-N-(2,3-difluorophenyl)-4-(4-methylphenyl)-2-oxopyrrolidine-3-carboxamide

Conditions

Conditions	Yield
With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide In dichloromethane; ethyl acetate at 20℃; for 17h;	92%

: 4519-40-8
2,3-difluoroanilline

: 2-bromobenzo[2,3][1,4]oxazepino[7,6-b]quinoline

: N-(2,3-difluorophenyl)benzo[2,3][1,4]oxazepino[7,6-b]quinolin-2-amine

Conditions

Conditions	Yield
With chloro(2-dicyclohexylphosphino-2’,4’,6’-triisopropyl-1,1‘-biphenyl)[2-(2’-amino-1,1‘-biphenyl’)]palladium(II); sodium t-butanolate In 1,4-dioxane at 90℃; for 0.75h; Buchwald-Hartwig Coupling; Microwave irradiation;	92%

: 4519-40-8
2,3-difluoroanilline

: 56-81-5
glycerol

: 7,8-Difluoroquinoline

Conditions

Conditions	Yield
Stage #1: 2,3-difluoroanilline; glycerol With sulfuric acid; sodium iodide at 150 - 180℃; for 4h; Stage #2: With sodium hydroxide In water at 60 - 70℃;	91%
Stage #1: 2,3-difluoroanilline With sulfuric acid at 0 - 20℃; for 1h; Stage #2: glycerol With sodium iodide at 150 - 180℃; for 3h;	91%
With sulfuric acid; sodium 3-nitrobenzenesulfonate at 140℃; for 4h; Condensation; cyclization;	86%
With sulfuric acid; sodium 3-nitrobenzenesulfonate In water at 135℃;
Stage #1: 2,3-difluoroanilline; glycerol With sulfuric acid; sodium 3-nitrobenzenesulfonate In water at 135℃; for 3.5h; Stage #2: With sodium hydroxide In water at 0 - 20℃;

: 4519-40-8
2,3-difluoroanilline

: 598-21-0
2-Bromoacetyl bromide

: 804550-60-5
2-bromo-N-(2,3-difluorophenyl)acetamide

Conditions

Conditions	Yield
With sodium hydroxide In diethyl ether at 5 - 20℃; for 1h;	91%
With sodium hydroxide In diethyl ether; water at 5 - 20℃; for 1.33333h;	91%
With potassium carbonate In dichloromethane for 5h;
With potassium carbonate In dichloromethane for 5h;

: 4519-40-8
2,3-difluoroanilline

: 2-bromo-9-methylbenzo[2,3][1,4]oxazepino[7,6-b]quinoline

: N-(2,3-difluorophenyl)-9-methylbenzo[2,3][1,4]oxazepino[7,6-b]quinolin-2-amine

Conditions

Conditions	Yield
With chloro(2-dicyclohexylphosphino-2’,4’,6’-triisopropyl-1,1‘-biphenyl)[2-(2’-amino-1,1‘-biphenyl’)]palladium(II); sodium t-butanolate In 1,4-dioxane at 90℃; for 0.75h; Buchwald-Hartwig Coupling; Inert atmosphere; Microwave irradiation; Sealed tube;	91%

: 4519-40-8
2,3-difluoroanilline

: 58756-32-4
1,2,3-thiadiazole-5-carbonyl azide

: 1-(2,3-difluorophenyl)-3-(1',2',3'-thiadiazol-5'-yl)urea

Conditions

Conditions	Yield
In toluene Heating;	90%

: 4519-40-8
2,3-difluoroanilline

: 79-04-9
chloroacetyl chloride

: 916483-51-7
2-chloro-N-(2,3-difluorophenyl)acetamide

Conditions

Conditions	Yield
With sodium hydroxide In diethyl ether; water at 5 - 20℃; for 1.33333h;	90%
With sodium hydroxide In diethyl ether; water at 5 - 20℃; for 1.33333h;	90%
Stage #1: 2,3-difluoroanilline With sodium hydrogencarbonate In chloroform at 20℃; for 0.25h; Stage #2: chloroacetyl chloride In chloroform at 20℃; for 2h;

: 4519-40-8
2,3-difluoroanilline

: 35675-46-8
3-methyl-4-nitro-benzoyl chloride

: 343975-33-7
N-(2,3-difluoro-phenyl)-3-methyl-4-nitro-benzamide

Conditions

Conditions	Yield
With pyridine for 1h; Heating;	89%

: 557770-91-9
2-(3-((7-(3-chloropropoxy)quinazolin-4-yl)amino)-1H-pyrazol-5-yl)acetic acid

: 4519-40-8
2,3-difluoroanilline

: 557770-88-4
2-(5-{[7-(3-chloropropoxy)quinazolin-4-yl]amino}-2H-pyrazol-3-yl)-N-(2,3-difluorophenyl)acetamide

Conditions

Conditions	Yield
With pyridine; trichlorophosphate at 0 - 20℃;	89%
With pyridine; trichlorophosphate In diethyl ether; ethyl acetate at 0 - 20℃; for 23.5h;	89%

: 10338-57-5
4-(piperidin-1-yl)benzaldehyde

: 4519-40-8
2,3-difluoroanilline

: 1268812-37-8
N-(4-(piperidin-1-yl)benzylidene)-2,3-difluorobenzenamine

Conditions

Conditions	Yield
With acetic acid In ethanol at 20℃; for 0.5h;	88%

: 4519-40-8
2,3-difluoroanilline

: 67-64-1
acetone

: 2,3-difluoro-N-isopropylaniline

Conditions

Conditions	Yield
With sodium tris(acetoxy)borohydride; acetic acid In dichloromethane at 20℃; for 12h;	88%

: 4519-40-8
2,3-difluoroanilline

: 175983-09-2
2-chloro-2-(diethoxymethyl)-3-methyloxirane

: 2-chloro-1,1-diethoxy-3-(2,3-difluorophenylamino)butan-2-ol

Conditions

Conditions	Yield
With sodium hydrogencarbonate In water; toluene at 40℃; for 36h; Temperature;	88%

: 14220-64-5, 39958-10-6, 15617-18-2
bis(benzonitrile)palladium(II) chloride

: 4519-40-8
2,3-difluoroanilline

: 919990-57-1
trans-[PdCl2(2,3-difluoroaniline)2]

Conditions

Conditions	Yield
In ethanol under N2; soln. of PdCl2(C6H5CN)2 (0.26 mmol) added to soln. of 2,3-difluoroaniline (0.52 mmol); refluxed (8 h); hot soln. filtered; solvent removed (vac.); elem. anal.;	87%

: 4519-40-8
2,3-difluoroanilline

: 814-68-6
acryloyl chloride

: N-(2,3-difluorophenyl)prop-2-enamide

Conditions

Conditions	Yield
With potassium carbonate In acetone at 20℃; for 16h; Inert atmosphere;	87%

: 385785-18-2
[2-(tritylamino)-1,3-thiazol-5-yl]acetic acid

: 4519-40-8
2,3-difluoroanilline

: 723281-43-4
N-(2,3-difluorophenyl)-2-[2-(tritylamino)-1,3-thiazol-5-yl]acetamide

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 50℃; for 18h;	85%

2,3-Difluoroaniline Chemical Properties

IUPAC Name: 2,3-Difluoroaniline
Molecular Formula: C₆H₅F₂N
Molecular Weight: 129.11 g/mol
SMILES: c1(c(N)cccc1F)F
InChI: InChI=1/C6H5F2N/c7-4-2-1-3-5(9)6(4)8/h1-3H,9H2
EINECS: 224-847-2
Product Categories: Other fluorin-contained compounds; Fluorobenzene Series; Fluorobenzene; Amines and Anilines; Anilines, Aromatic Amines and Nitro Compounds; Aniline; Miscellaneous; Amines; C2 to C6; Nitrogen Compounds
Index of Refraction: 1.52
Molar Refractivity: 30.47 cm³
Molar Volume: 100.1 cm³
Polarizability: 12.08×10^-24cm³
Surface Tension: 37.2 dyne/cm
Density: 1.289 g/cm³
Flash Point: 71.1 °C
Enthalpy of Vaporization: 41.29 kJ/mol
Boiling Point: 176.6 °C at 760 mmHg
Vapour Pressure of 2,3-Difluoroaniline (CAS NO.4519-40-8): 1.08 mmHg at 25 °C

2,3-Difluoroaniline Uses

2,3-Difluoroaniline (CAS NO.4519-40-8) is used as intermediate for liquid crystal and drugs.

2,3-Difluoroaniline Safety Profile

Hazard Codes: Harmful Xn, Irritant Xi
Risk Statements: 20/21/22-36/37/38
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-27-28-36/37/39-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S27:Take off immediately all contaminated clothing.
S28:After contact with skin, wash immediately with plenty of soap-suds.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S36:Wear suitable protective clothing.
RIDADR: 2941
WGK Germany: 3
Hazard Note: Irritant
HazardClass: 6.1
PackingGroup of 2,3-Difluoroaniline (CAS NO.4519-40-8): III

2,3-Difluoroaniline Specification

2,3-Difluoroaniline (CAS NO.4519-40-8), its Synonyms are 2,3-Difluoroaniline, 98% ; 2,3-Difluoroaniline 98% ; 2,3-Difluorophenylamine ; Benzenamine, 2,3-difluoro- . It is clear light orange liquid.

Product Name

2,3-Difluoroaniline

Synthetic route

2,3-Difluoroaniline Chemical Properties

2,3-Difluoroaniline Uses

2,3-Difluoroaniline Safety Profile

2,3-Difluoroaniline Specification

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