2,4,5-Trimethoxybenzaldehyde supplier

Name
2,4,5-Trimethoxybenzaldehyde
EINECS 224-713-3
CAS No. 4460-86-0
Article Data58
CAS DataBase
Density 1.133 g/cm³
Solubility <0.1 g/100 mL at 22 °C in water
Melting Point 112-114 °C(lit.)
Formula C₁₀H₁₂O₄
Boiling Point 334.7 °C at 760 mmHg
Molecular Weight 196.203
Flash Point 149 °C
Transport Information
Appearance white to light beige fine crystalline powder
Safety 22-24/25-45-36/37/39-27-26
Risk Codes 36/37/38-34
Molecular Structure
Hazard Symbols C
Synonyms 3,4,6-Trimethoxybenzaldehyde;Asaraldehyde;Asaronaldehyde;Asarylaldehyde;Gazarin;NSC 89299;
PSA 44.76000
LogP 1.52490

Synthetic route

: 1535-67-7
difluoromethyl phenyl sulfide

: 135-77-3
1,2,4-trimethoxy-benzene

: 4460-86-0
asaraldehyde

Conditions

Conditions	Yield
Stage #1: difluoromethyl phenyl sulfide; 1,2,4-trimethoxy-benzene With tin(IV) chloride In dichloromethane at 20℃; for 2h; Inert atmosphere; Stage #2: With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In dichloromethane; water; dimethyl sulfoxide at 20℃; for 2h;	98%

: 30038-31-4
(2,4,5-trimethoxyphenyl)methanol

: 4460-86-0
asaraldehyde

Conditions

Conditions	Yield
With copper(l) iodide; TEMPOL; N,N'-dimethyl-N,N'-bis(2-pyridylmethyl)ethane-1,2-diamine In acetonitrile at 20℃; for 2h; Inert atmosphere;	97%
With tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide In dichloromethane at 0℃; for 1.5h; Molecular sieve; Inert atmosphere;	96%
With tert.-butylhydroperoxide; eosin y In decane; acetonitrile at 25℃; for 36h; Inert atmosphere; Irradiation; Molecular sieve; Green chemistry; chemoselective reaction;	87%

: 2883-98-9
α-asarone

: 4460-86-0
asaraldehyde

Conditions

Conditions	Yield
With sodium periodate; osmium(VIII) oxide; N-benzyl-N,N,N-triethylammonium chloride In tetrahydrofuran; water microwave irradiation;	84%
With sodium periodate; osmium(VIII) oxide; N-benzyl-N,N,N-triethylammonium chloride In tetrahydrofuran; water Microwave irradiation;	82%

: 494-40-6, 2883-98-9, 5273-86-9
asarone

: 4460-86-0
asaraldehyde

Conditions

Conditions	Yield
With sodium periodate; osmium(VIII) oxide; N-benzyl-N,N,N-triethylammonium chloride In tetrahydrofuran; water at 100℃; Microwave irradiation;	83%
With chromium(VI) oxide
With potassium permanganate

: 5273-86-9
C12H16O3

: 4460-86-0
asaraldehyde

Conditions

Conditions	Yield
With sodium periodate; osmium(VIII) oxide; N-benzyl-N,N,N-triethylammonium chloride In tetrahydrofuran; water at 100℃; Microwave irradiation;	83%
With sodium periodate; osmium(VIII) oxide; N-benzyl-N,N,N-triethylammonium chloride In tetrahydrofuran; water for 0.0138889h; microwave irradiation;	82%
With dipyridinium dichromate; acetic acid In 1,4-dioxane for 0.333333h; Heating; Microwave irradiation;
With potassium permanganate; sodium hydrogencarbonate at 20℃;

: 135-77-3
1,2,4-trimethoxy-benzene

: 68-12-2, 33513-42-7
N,N-dimethyl-formamide

: 4460-86-0
asaraldehyde

Conditions

Conditions	Yield
With trichlorophosphate at 20℃; for 1h; Vilsmeier reaction;	81%
With trichlorophosphate at 0 - 80℃; for 3h; Vilsmeier-Haack Formylation; Inert atmosphere;	80%
With trichlorophosphate

: acetic acid acetoxy-(2,4,5-trimethoxy-phenyl)-methyl ester

: 4460-86-0
asaraldehyde

Conditions

Conditions	Yield
With ammonium acetate for 0.0125h; microwave irradiation;	77%

: 324067-40-5
C16H18N2O3

A: 4460-86-0
asaraldehyde

B: 1376268-31-3
4,5-bis(2,4,5-trimethoxyphenyl)-2-phenyl-2H-1,2,3-triazole

Conditions

Conditions	Yield
With copper(II) acetate monohydrate In toluene at 60℃; for 7h;	A n/a B 66%

: 877680-53-0
N-(chloromethyl)diformamide

: 135-77-3
1,2,4-trimethoxy-benzene

A: 4460-86-0
asaraldehyde

B: 14470-07-6
tris(2,4,5-trimethoxyphenyl)methane

Conditions

Conditions	Yield
With aluminum (III) chloride In chlorobenzene at 0 - 18℃; for 22h;	A 56% B 24%

...Expand

: 17598-03-7
5-ethenyl-1,2,4-trimethoxybenzene

: 4460-86-0
asaraldehyde

Conditions

Conditions	Yield
With 1-hydroxy-pyrrolidine-2,5-dione; graphitic carbon nitride; oxygen In acetonitrile at 20℃; Inert atmosphere; Irradiation;	52%

: 135-77-3
1,2,4-trimethoxy-benzene

: 149-73-5
trimethyl orthoformate

A: 4460-86-0
asaraldehyde

B: 14470-07-6
tris(2,4,5-trimethoxyphenyl)methane

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate In neat liquid at 20℃; for 1h; Friedel-Crafts Alkylation;	A 30% B 46%

...Expand

: 1535-67-7
difluoromethyl phenyl sulfide

: 135-77-3
1,2,4-trimethoxy-benzene

A: 4460-86-0
asaraldehyde

B: bis(2,4,5-trimethoxyphenyl)phenylsulfanylmethane

C: 1-(diphenylsulfanylmethyl)-2,4,5-trimethoxybenzene

Conditions

Conditions	Yield
With tin(IV) chloride In dichloromethane at 20℃; for 2h; Inert atmosphere;	A 37% B 6% C 42%
With aluminum (III) chloride In dichloromethane at 20℃; for 2h; Inert atmosphere;	A 7% B 23% C 6%

...Expand

: 67-56-1
methanol

: 120-14-9
3,4-dimethoxy-benzaldehyde

: 4460-86-0
asaraldehyde

Conditions

Conditions	Yield
With dipotassium peroxodisulfate; palladium diacetate; 3-trifluoromethylaniline In dichloromethane at 60℃; for 24h; Sealed tube;	33%

: 1535-67-7
difluoromethyl phenyl sulfide

: 135-77-3
1,2,4-trimethoxy-benzene

A: 4460-86-0
asaraldehyde

B: 14470-07-6
tris(2,4,5-trimethoxyphenyl)methane

C: bis(2,4,5-trimethoxyphenyl)phenylsulfanylmethane

D: 1-(diphenylsulfanylmethyl)-2,4,5-trimethoxybenzene

Conditions

Conditions	Yield
With titanium tetrachloride In dichloromethane at 20℃; for 2h; Inert atmosphere;	A 20% B 3% C 24% D 25%

...Expand

: 74-90-8
hydrogen cyanide

: 135-77-3
1,2,4-trimethoxy-benzene

: 4460-86-0
asaraldehyde

Conditions

Conditions	Yield
With hydrogenchloride; aluminium trichloride; benzene at 40 - 50℃; Zersetzung des Reaktionsgemisches mit Eiswasser;

: 494-40-6, 2883-98-9, 5273-86-9
asarone

A: 4460-86-0
asaraldehyde

B: 490-64-2
asaronic acid

Conditions

Conditions	Yield
With potassium permanganate; water

: 24160-53-0
2,4,5-trimethoxycinnamic acid

A: 4460-86-0
asaraldehyde

B: 490-64-2
asaronic acid

: 95-01-2
2,4-Dihydroxybenzaldehyde

: 4460-86-0
asaraldehyde

Conditions

Conditions	Yield
With sodium hydroxide; dipotassium peroxodisulfate
Multi-step reaction with 3 steps 1: Br2; NaClO3 2: CuCl 3: NaOH View Scheme

: 51061-83-7
2,4-dihydroxy-5-methoxybenzaldehyde

: 74-88-4
methyl iodide

: 4460-86-0
asaraldehyde

Conditions

Conditions	Yield
With potassium carbonate; acetone

: 14382-91-3
2-hydroxy-4,5-dimethoxybenzaldehyde

: 74-88-4
methyl iodide

: 4460-86-0
asaraldehyde

Conditions

Conditions	Yield
With potassium carbonate; acetone

: 29865-97-2
2,5-dihydroxy-4-methoxy-benzaldehyde

: 74-88-4
methyl iodide

: 4460-86-0
asaraldehyde

Conditions

Conditions	Yield
With potassium carbonate; acetone

: 67-56-1
methanol

: 2883-98-9
α-asarone

A: 5273-86-9
C12H16O3

B: 4460-86-0
asaraldehyde

C: 82645-86-1
3-Methoxy-3-(2,4,5-trimethoxyphenyl)-propan

Conditions

Conditions	Yield
for 4h; Irradiation;

...Expand

: 5273-86-9
C12H16O3

A: 2883-98-9
α-asarone

B: 4460-86-0
asaraldehyde

C: 73036-51-8
andamanicin

D: 99217-07-9
(Z)-3-(2,4,5-trimethoxyphenyl)acrylaldehyde

Conditions

Conditions	Yield
for 720h; Irradiation; Further byproducts given;	A 0.26 g B 1.18 g C 0.28 g D 46 mg

...Expand

: 5273-86-9
C12H16O3

A: 2883-98-9
α-asarone

B: 4460-86-0
asaraldehyde

C: 73036-51-8
andamanicin

D: 99217-07-9
(Z)-3-(2,4,5-trimethoxyphenyl)acrylaldehyde

E: 99217-07-9, 106128-88-5, 99217-06-8
trans 2,4,5-trimethoxy cinnamaldehyde

Conditions

Conditions	Yield
for 720h; Mechanism; Irradiation;	A 0.26 g B 1.18 g C 0.28 g D 46 mg E 0.19 g

...Expand

: 5273-86-9
C12H16O3

A: 2883-98-9
α-asarone

B: 4460-86-0
asaraldehyde

C: 73036-51-8
andamanicin

D: 99217-07-9, 106128-88-5, 99217-06-8
trans 2,4,5-trimethoxy cinnamaldehyde

Conditions

Conditions	Yield
for 720h; Irradiation; Further byproducts given;	A 0.26 g B 1.18 g C 0.28 g D 0.19 g

...Expand

: 5353-15-1
1-allyl-2,4,5-trimethoxybenzene

: 4460-86-0
asaraldehyde

Conditions

Conditions	Yield
With sodium dichromate In acetic acid; benzene for 6h; Heating;

calmus oil: calmus oil

: 4460-86-0
asaraldehyde

Conditions

Conditions	Yield
With sodium hydrogensulfite beim Stehen an der Luft;
With water; sodium hydrogensulfite

: 494-40-6, 2883-98-9, 5273-86-9
asarone

: 64-19-7
acetic acid

K2cr2O7: K2cr2O7

: 4460-86-0
asaraldehyde

...Expand

: 494-40-6, 2883-98-9, 5273-86-9
asarone

KMnO4: KMnO4

A: 4460-86-0
asaraldehyde

B: 490-64-2
asaronic acid

...Expand

: 58621-39-9
2-acetyl-6-allylphenol

: 4460-86-0
asaraldehyde

: 1-(2-hydroxy-3-allyl-phenyl)-3-(2,4,5-trimethoxy-phenyl)-propenone

Conditions

Conditions	Yield
With potassium hydroxide In ethanol for 191h;	100%
With potassium hydroxide In ethanol for 191h; aldol condensation;

: 4460-86-0
asaraldehyde

: 14894-74-7
1,2,4-trimethoxy-5-methylbenzene

Conditions

Conditions	Yield
With triethylsilane; chloro-trimethyl-silane In acetonitrile	100%
Multi-step reaction with 2 steps 1: hydrazine hydrate / bis-(2-hydroxy-ethyl) ether / 0.12 h / Irradiation 2: KOH / bis-(2-hydroxy-ethyl) ether / 0.28 h / Irradiation View Scheme

: 4460-86-0
asaraldehyde

: 74-89-5
methylamine

: 1246401-41-1
C11H15NO3

Conditions

Conditions	Yield
at 20℃; for 12h;	100%

: 867-13-0
diethoxyphosphoryl-acetic acid ethyl ester

: 4460-86-0
asaraldehyde

: 14469-89-7
2,4,5-trimethoxycinnamic acid ethyl ester

Conditions

Conditions	Yield
With potassium carbonate In tetrahydrofuran for 20h; Horner-Wadsworth-Emmons reaction; Reflux;	100%

: 79-24-3
Nitroethane

: 4460-86-0
asaraldehyde

: 134040-35-0, 17231-84-4
2,4,5-trimethoxy-β-methyl-β-nitrostyrene

Conditions

Conditions	Yield
With ammonium acetate for 0.75h; Reflux;	99.5%
With ammonium acetate
With ammonium acetate In acetic acid

: 4460-86-0
asaraldehyde

: 14382-91-3
2-hydroxy-4,5-dimethoxybenzaldehyde

Conditions

Conditions	Yield
Stage #1: asaraldehyde With boron trichloride In dichloromethane at -78 - 20℃; for 3h; Stage #2: With hydrogenchloride; water In dichloromethane at 0℃;	99%
With boron tribromide In dichloromethane at 0 - 20℃; for 16h; Inert atmosphere;	99%
With boron trichloride In dichloromethane at -78 - 20℃; for 3h;	98%

: 4460-86-0
asaraldehyde

: 615-43-0
2-iodophenylamine

: N-(2,4,5-trimethoxybenzyl)-2-iodobenzenamine

Conditions

Conditions	Yield
Stage #1: asaraldehyde; 2-iodophenylamine With acetic acid In methanol at 20℃; for 0.5h; Inert atmosphere; Stage #2: With sodium cyanoborohydride In methanol at 0 - 20℃; for 95h; Inert atmosphere;	99%

: 4460-86-0
asaraldehyde

: 108-98-5
thiophenol

: 1-(diphenylsulfanylmethyl)-2,4,5-trimethoxybenzene

Conditions

Conditions	Yield
With indium(III) bromide In water at 20℃; for 3h;	98%

: 3027-05-2
N,N'-diacetylpiperazin-2,5-dione

: 4460-86-0
asaraldehyde

: 709615-05-4
1-Acetyl-3-[1-(2,4,5-trimethoxy-phenyl)-meth-(Z)-ylidene]-piperazine-2,5-dione

Conditions

Conditions	Yield
With potassium tert-butylate; tert-butyl alcohol In dichloromethane at 20℃; for 4h;	98%

: 4460-86-0
asaraldehyde

: 139756-02-8
4-amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamide

: 1610875-93-8
1-methyl-3-propyl-5-(2,4,5-trimethoxyphenyl)-1H-pyrazolo[4,3-d]pyrimidin-7-(6H)-one

Conditions

Conditions	Yield
With dipotassium peroxodisulfate In water; dimethyl sulfoxide at 100℃; for 0.05h; Sealed tube; Microwave irradiation;	98%
Stage #1: asaraldehyde; 4-amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamide In ethanol at 60℃; for 0.5h; Stage #2: With oxygen; copper dichloride In ethanol at 75℃; for 0.5h;	87%

: 4460-86-0
asaraldehyde

: 30038-31-4
(2,4,5-trimethoxyphenyl)methanol

Conditions

Conditions	Yield
With methanol; sodium tetrahydroborate at 0 - 20℃; for 18h; Inert atmosphere; Schlenk technique;	97%
With sodium tetrahydroborate In methanol for 0.5h;	84%
With ethanol; platinum Hydrogenation;

: 4083-57-2
2,4-dimethylpent-3-ylamine

: 4460-86-0
asaraldehyde

: 2,4,5-Trimethoxybenzaldehyde 2,4-dimethylpent-3-ylimine

Conditions

Conditions	Yield
	97%
With toluene-4-sulfonic acid In toluene for 3h; Heating / reflux;	96%
With toluene-4-sulfonic acid In toluene for 3h; Heating / reflux;	96%

: (1-methoxyethyl)triphenylphosphonium tetrafluoroborate

: 4460-86-0
asaraldehyde

: 1422453-77-7
1-hydroxy-1-(2,4,5-trimethoxyphenyl)propan-2-one

Conditions

Conditions	Yield
Stage #1: (1-methoxyethyl)triphenylphosphonium tetrafluoroborate With n-butyllithium In tetrahydrofuran at -78℃; for 0.333333h; Inert atmosphere; Stage #2: asaraldehyde In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere;	97%

: 85-44-9
phthalic anhydride

: 4460-86-0
asaraldehyde

: 105-56-6
ethyl 2-cyanoacetate

: ethyl 3‑amino‑5,10‑dioxo‑1‑(2,4,5‑trimethoxyphenyl)‑5,10‑dihydro‑1H‑pyrazolo[1,2‑b]phthalazine‑2‑carboxylate

Conditions

Conditions	Yield
With hydrazine hydrate In water at 60℃; for 0.666667h; Green chemistry;	97%

...Expand

: 107-03-9
1-thiopropane

: 4460-86-0
asaraldehyde

: 1-(bis-propylsulfanyl-methyl)-2,4,5-trimethoxy-benzene

Conditions

Conditions	Yield
With indium(III) bromide In dichloromethane at 20℃; for 1h;	96%

: 4460-86-0
asaraldehyde

: 106-65-0
Dimethyl succinate

: 74018-30-7
Asarylidenbernsteinsaeure

Conditions

Conditions	Yield
With potassium tert-butylate In tert-butyl alcohol for 2h; Heating;	96%

: 4460-86-0
asaraldehyde

: 5731-01-1
4-bromo-4'-acetylbiphenyl

: 1256153-24-8
1-[(4-(4-bromophenyl)phenyl)]-3-(2,4,5-trimethoxyphenyl)prop-2-en-1-one

Conditions

Conditions	Yield
In methanol at 75℃; Claisen-Schmidt condensation; Ionic liquid; Microwave irradiation;	96%

: 4460-86-0
asaraldehyde

: 832-58-6
1-(2,4,6-trimethoxyphenyl)ethanone

: 73694-37-8
(2E)-1-(2,4,6-trimethoxyphenyl)-3-(2,4,5-trimethoxyphenyl)-2-propen-1-one

Conditions

Conditions	Yield
With potassium hydroxide In ethanol; water at 20℃; Claisen-Schmidt Condensation;	96%
With lithium hydroxide monohydrate In ethanol at 20℃; for 168h; Claisen-Schmidt Condensation;	78%
With lithium hydroxide monohydrate In ethanol at 20℃; for 168h; Claisen-Schmidt Condensation;	78%
With potassium hydroxide at 20℃; for 0.0833333h; Claisen-Schmidt Condensation; Inert atmosphere;	68%

: 4225-35-8
4,6-dimethoxycoumaranone

: 4460-86-0
asaraldehyde

: (Z)-benzylidene-4,6,2',4',5'-pentamethoxybenzylidenebenzofuran-3(2H)-one

Conditions

Conditions	Yield
With potassium hydroxide In methanol at 20℃; for 0.5h;	95%
With potassium hydroxide In methanol at 20℃; for 1h;

: 1059117-37-1
3-(3',4',5'-trimethoxyphenyl)-4,5,6-trimethoxy-indan-1-one

: 4460-86-0
asaraldehyde

: 1375084-23-3
3-(3',4',5'-trimethoxyphenyl)-4,5,6-trimethoxy-2-(2'',4'',5''-trimethoxybenzylidene)-indan-1-one

Conditions

Conditions	Yield
With potassium hydroxide In methanol at 20℃;	95%

: 4460-86-0
asaraldehyde

: 98-86-2
acetophenone

: 1393480-79-9
(2E)‑1‑phenyl‑3‑(2,4,5‑trimethoxyphenyl)prop‑2‑en‑1‑one

Conditions

Conditions	Yield
With potassium hydroxide In ethanol; water at 20℃; Claisen-Schmidt Condensation;	95%
With sodium hydroxide In ethanol at 20℃; for 3h; Claisen-Schmidt Condensation;	82%
With potassium hydroxide In ethanol; water at 20℃; Claisen-Schmidt Condensation;	79%
With sodium hydroxide In ethanol at 20℃; for 48h; Claisen-Schmidt Condensation;	74%
With sodium hydroxide at 20℃; for 48h; Claisen-Schmidt Condensation;	31%

: 4460-86-0
asaraldehyde

: 31405-72-8
2,5-diacetoxyacetophenone

: (E)-1-(2,5-Dicetoxyphenyl)-3-(2,4,5-trimethoxyphenyl)prop-2-en-1-one

Conditions

Conditions	Yield
With potassium hydroxide In ethanol; water at 20℃; Claisen-Schmidt Condensation;	95%

: 85-44-9
phthalic anhydride

: 4460-86-0
asaraldehyde

: 109-77-3
malononitrile

: 3‑amino‑5,10‑dioxo‑1‑(2,4,5‑trimethoxyphenyl)‑5,10‑dihydro‑1H‑pyrazolo[1,2‑b]phthalazine‑2‑carbonitrile

Conditions

Conditions	Yield
With hydrazine hydrate In water at 60℃; for 0.5h; Catalytic behavior; Reagent/catalyst; Solvent; Temperature; Green chemistry;	95%

...Expand

: 2033-24-1
cycl-isopropylidene malonate

: 4460-86-0
asaraldehyde

: 117646-11-4
5-(2,4,5-trimethoxybenzylidene)-2,2-dimethyl-[1,3]dioxane-4,6-dione

Conditions

Conditions	Yield
In N,N-dimethyl-formamide for 12h; Ambient temperature;	94%
In methanol at 20℃; for 6h;	46%
In methanol at 20℃; Knoevenagel condensation;
In N,N-dimethyl-formamide

: 4460-86-0
asaraldehyde

: 93-08-3
methyl 2-naphthyl ketone

: 41343-22-0
(2E)-1-(2-naphthyl)-3-(2,4,5-trimethoxyphenyl)-2-propen-1-one

Conditions

Conditions	Yield
With potassium hydroxide In methanol at 20℃; for 24h;	94%
With potassium hydroxide In methanol at 20℃; for 24h;

: 4460-86-0
asaraldehyde

: 99-90-1
para-bromoacetophenone

: 941607-52-9
1-(4-bromophenyl)-3-(2,4,5-trimethoxyphenyl)prop-2-en-1-one

Conditions

Conditions	Yield
In methanol at 75℃; Claisen-Schmidt condensation; Ionic liquid; Microwave irradiation;	94%
With sodium hydroxide In ethanol for 2h;

: 4460-86-0
asaraldehyde

: 100-06-1
1-(4-methoxyphenyl)ethanone

: 1003377-77-2
(E)-1-(4-methoxyphenyl)-3-(2,4,5-trimethoxyphenyl)prop-2-en-1-one

Conditions

Conditions	Yield
Stage #1: 1-(4-methoxyphenyl)ethanone With sodium hydroxide In ethanol; water at 20℃; for 0.0833333h; Claisen-Schmidt Condensation; Stage #2: asaraldehyde at 20℃; Claisen-Schmidt Condensation;	94%
With lithium hydroxide monohydrate In ethanol at 20℃; for 15h; Claisen-Schmidt Condensation;	92%
With lithium hydroxide monohydrate In ethanol at 20℃; for 15h; Claisen-Schmidt Condensation;	92%

: 524-38-9
N-hydroxyphthalimide

: 4460-86-0
asaraldehyde

: 1441984-87-7
1,3-dioxoisoindolin-2-yl 2,4,5-trimethoxybenzoate

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; tetra-(n-butyl)ammonium iodide In decane; ethyl acetate at 20 - 70℃; for 8h;	94%

2,4,5-Trimethoxybenzaldehyde Specification

1. Introduction of 2,4,5-Trimethoxy Benzaldehyde
2,4,5-Trimethoxy Benzaldehyde is pharmaceutical intermediates used for the preparation of asarone.

2. Properties of 2,4,5-Trimethoxy Benzaldehyde
Melting point: 112-114 °C
Index of Refraction: 1.524
Molar Refractivity: 53.04 cm³
Molar Volume: 173.1 cm³
Surface Tension: 35.4 dyne/cm
Density: 1.133 g/cm³
Flash Point: 149 °C
Enthalpy of Vaporization: 57.77 kJ/mol
Boiling Point: 334.7 °C at 760 mmHg
Vapour Pressure: 0.000125 mmHg at 25°C
Classification Code: Mutation data

3. Toxicity of 2,4,5-Trimethoxy Benzaldehyde

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
bird - wild	LD50	oral	422mg/kg (422mg/kg)		Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.

5. Safety Information of 2,4,5-Trimethoxy Benzaldehyde
Hazard Codes:C

Risk Statements:36/37/38-34
36/37/38:Irritating to eyes, respiratory system and skin
34:Causes burns
Safety Statements:22-24/25-45-36/37/39-27-26
22:Do not breathe dust
24/25:Avoid contact with skin and eyes
45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
36/37/39:Wear suitable protective clothing, gloves and eye/face protection
27:Take off immediately all contaminated clothing
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
WGK Germany:3
RTECS:CU8460000
Hazardous Substances Data:4460-86-0(Hazardous Substances Data)

6. Use of 2,4,5-Trimethoxy Benzaldehyde
2,4,5-Trimethoxy Benzaldehyd is used as a pharmaceutical intermediate mainly for the preparation of Asarone.

Product Name

2,4,5-Trimethoxybenzaldehyde

Synthetic route

2,4,5-Trimethoxybenzaldehyde Specification

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