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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 1,2,4-Trimethoxybenzene supplier in China

Cas:135-77-3

Min.Order:0 Metric Ton

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Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell Package:According to the demand of customer Application:Pharmaceutical intermediates Transportation:by air or by sea Port:shanghai

1,2,4-Trimethoxybenzene

Cas:135-77-3

Min.Order:1 Kilogram

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Type:Manufacturers

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Large Stock 99.0% 6-hydroxy-2-naphthalenesulfonic acid sodium salt 135-77-3 Producer

Cas:135-77-3

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price in China. If you are looking for the product’s supplier in China, DayangChem is your best choice. As a leading manufacturer and supplier of chemicals in China, Day

1,2,4-Trimethoxybenzene

Cas:135-77-3

Min.Order:1 Kilogram

FOB Price: $4.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Hydroxyhydroquinone trimethyl ether

Cas:135-77-3

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM--135-77-3--1,2,4-Trimethoxybenzene factory price Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established stable business

TIANFUCHEM--135-77-3--1,2,4-Trimethoxybenzene factory price

Cas:135-77-3

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

1,2,4-Trimethoxybenzene CAS NO.135-77-3

Cas:135-77-3

Min.Order:1 Gram

FOB Price: $1.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 135-77-3 with best quality

Cas:135-77-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

1,2,4-Trimethoxybenzene

Cas:135-77-3

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Manufacturers

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Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is

1,2,4-Trimethoxybenzene CAS NO 135-77-3

Cas:135-77-3

Min.Order:1 Kilogram

Negotiable

Type:Other

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Hangzhou Sartort Biopharma Co., Ltd

Appearance:Colorless to Almost colorless clear liquid Storage:Sealed in dry,Room Temperature Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Any port in China

Factory supply 1,2,4-Trimethoxybenzene

Cas:135-77-3

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1,2,4-Trimethoxybenzene 135-77-3

Cas:135-77-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

1,2,4-Trimethoxybenzene

Cas:135-77-3

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Changchun Artel lmport and Export trade company

Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,MoneyGram Package 10g,20g,50g,100g,500g,1KGS,

1,2,4-Trimethoxybenzene CAS NO.135-77-3

Cas:135-77-3

Min.Order:10 Gram

Negotiable

Type:Trading Company

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Hebei Mojin Biotechnology Co.,Ltd

Hebei Mojin Biological Technology Co., Ltd. is specialize in the production of chemical raw materials and reagents,located in Shijiazhuang, Hebei Province. In recent decades, under the efforts of all staff, in Shandong, Henan, Guangdong and many othe

1, 2, 4-Trimethoxybenzene CAS 135-77-3

Cas:135-77-3

Min.Order:1 Kilogram

FOB Price: $20.0 / 40.0

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1,2,4-Trimethoxybenzene

Cas:135-77-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

1,2,4-Trimethoxybenzene

Cas:135-77-3

Min.Order:0

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Type:Manufacturers

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Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: 1,2,4-Trimethoxybenzene Synonyms: HYDROXYHYDROQUINONE TRIMETHYL ETHER;1,2,4-TRIMETHOXYBENZENE;1,2,4-trimethoxy-benzen;Benzene, 1,2,4-trimethoxy-;1.2.4-Trimethoxy benzone;1,2,4-Benzenetriol trimethyl ether;TMB 124;1,4,5-Trimethoxybe

1,2,4-Trimethoxybenzene Manufactuered in China best quality

Cas:135-77-3

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures

1,2,4-Trimethoxybenzene

Cas:135-77-3

Min.Order:1 Kilogram

FOB Price: $80.0 / 100.0

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

1,2,4-Trimethoxybenzene

Cas:135-77-3

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1,2,4-Trimethoxybenzene

Cas:135-77-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

1,2,4-TRIMETHOXYBENZENE

Cas:135-77-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

1,2,4-Trimethoxybenzene

Cas:135-77-3

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

1,2,4-Trimethoxybenzene

Cas:135-77-3

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

1,2,4-Trimethoxybenzene

Cas:135-77-3

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:Clear colorless liquid or solid Storage:in shade Package:25kg/drum, or as per your request. Application:For medicine , pesticide intermediates Transportation:as per your request.

1,2,4-Trimethoxybenzene

Cas:135-77-3

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h

Factory Supply 1,2,4-Trimethoxybenzene

Cas:135-77-3

Min.Order:0

Negotiable

Type:Other

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

1,2,4-Trimethoxybenzene

Cas:135-77-3

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

1,2,4-Trimethoxybenzene

Cas:135-77-3

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Siwei Development Group Ltd.

Product name: 1,2,4-Trimethoxybenzene CAS No.:135-77-3 Molecule Formula:C9H12O3 Molecule Weight:168.19 Purity: 99.0% Package: 25kg/drum Description:White or yellowish white powder Manufacture Standards:Enterprise Standard

High Quality 1,2,4-Trimethoxybenzene

Cas:135-77-3

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Synthetic route

1,2,4-triacetoxybenzene
613-03-6

1,2,4-triacetoxybenzene

dimethyl sulfate
77-78-1

dimethyl sulfate

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

Conditions
ConditionsYield
Stage #1: 1,2,4-triacetoxybenzene With methanol; potassium hydroxide at 40℃; for 0.133333h; Inert atmosphere;
Stage #2: dimethyl sulfate With potassium carbonate at 60℃; for 0.5h; pH=8.5; Reagent/catalyst; Inert atmosphere;
99.4%
With methanol; sodium hydroxide
Alkaline aq. solution;
1,2,4-Trihydroxybenzene
533-73-3

1,2,4-Trihydroxybenzene

dimethyl sulfate
77-78-1

dimethyl sulfate

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 20℃; for 12h;99%
With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 16h; Inert atmosphere;96%
With sodium hydroxide
2,4-dibromoanisole
21702-84-1

2,4-dibromoanisole

sodium methylate
124-41-4

sodium methylate

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

Conditions
ConditionsYield
With methanol; Methyl formate; copper(l) chloride at 115℃; for 2h; Autoclave; Green chemistry;98%
3,4-dimethoxyphenol
2033-89-8

3,4-dimethoxyphenol

methyl iodide
74-88-4

methyl iodide

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

Conditions
ConditionsYield
Stage #1: 3,4-dimethoxyphenol With potassium carbonate In acetone at 40 - 45℃; for 1h; Inert atmosphere;
Stage #2: methyl iodide In acetone for 7h; Reflux; Inert atmosphere;
97%
With n-butyllithium In tetrahydrofuran at 0℃;
3,4-dimethoxyphenol
2033-89-8

3,4-dimethoxyphenol

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

Conditions
ConditionsYield
With magnesium oxide In N,N-dimethyl-formamide at 170℃; for 0.5h; Microwave irradiation; Green chemistry;96%
2,5-dimethoxyphenol
18113-18-3

2,5-dimethoxyphenol

dimethyl sulfate
77-78-1

dimethyl sulfate

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

Conditions
ConditionsYield
With potassium hydroxide In dimethyl sulfoxide95%
3,4-dimethoxyphenol
2033-89-8

3,4-dimethoxyphenol

dimethyl sulfate
77-78-1

dimethyl sulfate

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

Conditions
ConditionsYield
With potassium hydroxide for 1.5h; Heating;90%
1-styryl-2,4,5-trimethoxybenzene

1-styryl-2,4,5-trimethoxybenzene

A

2-phenylnaphthalene
612-94-2

2-phenylnaphthalene

B

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

Conditions
ConditionsYield
With trifluoroacetic acid In water at 80℃; for 0.5h; Diels-Alder Cycloaddition;A 90%
B n/a
2,4,5-trimethoxybenzoic acid potassium salt

2,4,5-trimethoxybenzoic acid potassium salt

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

Conditions
ConditionsYield
With trifluoroacetic acid; palladium(II) trifluoroacetate In dimethyl sulfoxide at 70℃;55%
Stage #1: 2,4,5-trimethoxybenzoic acid potassium salt With palladium(II) trifluoroacetate In dimethyl sulfoxide at 80℃; for 0.5h;
Stage #2: With trifluoroacetic acid In dimethyl sulfoxide at 70℃;
55%
N-acetylindole
576-15-8

N-acetylindole

sodium 2,4,5-trimethoxybenzoate
83813-98-3

sodium 2,4,5-trimethoxybenzoate

A

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

B

2-(2',4',5'-trimethoxyphenyl)-N-acetylindole
1235306-66-7

2-(2',4',5'-trimethoxyphenyl)-N-acetylindole

C

2,2',4,4',5,5'-hexamethoxybiphenyl
1702-67-6

2,2',4,4',5,5'-hexamethoxybiphenyl

Conditions
ConditionsYield
Stage #1: sodium 2,4,5-trimethoxybenzoate With palladium(II) trifluoroacetate In dimethyl sulfoxide at 80℃; for 0.5h; Inert atmosphere;
Stage #2: N-acetylindole With dimethyl sulfoxide; propionic acid In 1,4-dioxane at 80℃; for 15h; Inert atmosphere;
A 51%
B 13%
C 11%
4-nitro-1H-pyrazole
2075-46-9

4-nitro-1H-pyrazole

1,1,4,4-tetramethoxycyclohexa-2,5-diene
15791-03-4

1,1,4,4-tetramethoxycyclohexa-2,5-diene

A

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

B

1,4-dimethoxy-2-(4-nitropyrazol-1-yl)benzene

1,4-dimethoxy-2-(4-nitropyrazol-1-yl)benzene

Conditions
ConditionsYield
at 110℃; for 5h;A 44%
B 44%
asaronic acid
490-64-2

asaronic acid

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

Conditions
ConditionsYield
With silver(I) acetate; potassium carbonate In 1-methyl-pyrrolidin-2-one at 120℃; for 16h; Inert atmosphere;43%
With palladium(II) trifluoroacetate; trifluoroacetic acid In dimethyl sulfoxide; N,N-dimethyl-formamide at 70℃; for 24h;25%
With extinguished lime; calcium carbonate bei der Destillation;
With Tetrabutylammonium hydrogen diacetate; silver carbonate; tricyclohexylphosphine In 1,2-dimethoxyethane at 120℃; for 24h; Inert atmosphere;90 %Chromat.
3,5-dimethyl-4-nitro-1H-pyrazole
14531-55-6

3,5-dimethyl-4-nitro-1H-pyrazole

1,1,4,4-tetramethoxycyclohexa-2,5-diene
15791-03-4

1,1,4,4-tetramethoxycyclohexa-2,5-diene

A

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

B

2-(3,5-dimethyl-4-nitropyrazol-1-yl)-1,4-dimethoxybenzene

2-(3,5-dimethyl-4-nitropyrazol-1-yl)-1,4-dimethoxybenzene

Conditions
ConditionsYield
at 110℃; for 5h;A 36%
B 33%
2',4'-dihydroxy-4-acetophenone
89-84-9

2',4'-dihydroxy-4-acetophenone

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

Conditions
ConditionsYield
at 50℃; Reaktion ueber mehrere Stufen;
1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone
487-49-0

1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

Conditions
ConditionsYield
With sodium hydroxide; dihydrogen peroxide at 50℃; Reaktion ueber mehrere Stufen;
methoxyhydroquinone
824-46-4

methoxyhydroquinone

dimethyl sulfate
77-78-1

dimethyl sulfate

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

2,4,5-trihydroxybenzoic acid
610-90-2

2,4,5-trihydroxybenzoic acid

dimethyl sulfate
77-78-1

dimethyl sulfate

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

Conditions
ConditionsYield
With potassium hydroxide
methoxyhydroquinone
824-46-4

methoxyhydroquinone

methyl iodide
74-88-4

methyl iodide

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

Conditions
ConditionsYield
With potassium hydroxide
2,4-dimethoxyphenol
13330-65-9

2,4-dimethoxyphenol

sodium methylate
124-41-4

sodium methylate

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

Conditions
ConditionsYield
In N,N,N,N,N,N-hexamethylphosphoric triamide
2-chloro-1,4-dimethoxybenzene
2100-42-7

2-chloro-1,4-dimethoxybenzene

potassium methanolate
865-33-8

potassium methanolate

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

Conditions
ConditionsYield
With 18-crown-6 ether; iodine; chromium(0) hexacarbonyl 1.) diglyme, cyclohexane, reflux, 95 h, 2.) benzene, 70 deg C, 3.5 h, 3.) THF, R.T., 30 min; Yield given. Multistep reaction;
1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)ethanol
17078-88-5

1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)ethanol

sodium methylate
124-41-4

sodium methylate

A

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

B

1-methoxy-2-(methoxymethoxy)benzene
73220-26-5

1-methoxy-2-(methoxymethoxy)benzene

C

3,4-dimethoxy-benzaldehyde
120-14-9

3,4-dimethoxy-benzaldehyde

D

2-methoxy-phenol
90-05-1

2-methoxy-phenol

Conditions
ConditionsYield
With sodium perchlorate In methanol; dichloromethane Product distribution; Mechanism; anodic oxidation (undivided cell, Pt foil anode, W wire cathode, 50 mA, 3 F mol-1), other substrates;
4-methoxy-phenol
150-76-5

4-methoxy-phenol

dimethyl sulfate
77-78-1

dimethyl sulfate

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

Conditions
ConditionsYield
With oxygen; copper; sodium carbonate; copper(I) chloride 1.) CH3CN; Multistep reaction;
(+-)-2.4-dihydroxy-benzoin

(+-)-2.4-dihydroxy-benzoin

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

Conditions
ConditionsYield
With sodium hydroxide; dihydrogen peroxide at 50℃; Reaktion ueber mehrere Stufen;
asaronic acid
490-64-2

asaronic acid

lime/chalk/

lime/chalk/

A

carbon dioxide
124-38-9

carbon dioxide

B

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

Conditions
ConditionsYield
bei der Destillation;
methanol
67-56-1

methanol

diazotized 6-amino-2.3-dimethoxy-benzoic acid

diazotized 6-amino-2.3-dimethoxy-benzoic acid

A

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

B

2,3-dimethoxybenzoic acid
1521-38-6

2,3-dimethoxybenzoic acid

Conditions
ConditionsYield
With hydrogenchloride
methanol
67-56-1

methanol

2,4,5-trihydroxybenzoic acid
610-90-2

2,4,5-trihydroxybenzoic acid

dimethyl sulfate
77-78-1

dimethyl sulfate

KOH-solution

KOH-solution

A

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

B

asaronic acid
490-64-2

asaronic acid

C

2,2',4,4',5,5'-hexamethoxybiphenyl
1702-67-6

2,2',4,4',5,5'-hexamethoxybiphenyl

D

2-hydroxy-4,5-dimethoxybenzoic acid
5722-93-0

2-hydroxy-4,5-dimethoxybenzoic acid

1,2,4-trimethoxybenzene radical cation
135-77-3

1,2,4-trimethoxybenzene radical cation

7,8-dihydro-8-oxo-2'-deoxyguanosine
88847-89-6

7,8-dihydro-8-oxo-2'-deoxyguanosine

A

2-Amino-8-hydroxy-9-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one

2-Amino-8-hydroxy-9-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one

B

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

Conditions
ConditionsYield
In water at 20 - 25℃; pH=3.0; Kinetics; Equilibrium constant; Oxidation;
p-benzoquinone
106-51-4

p-benzoquinone

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: Alkaline aq. solution
View Scheme
sodium 2,4,5-trimethoxybenzoate
83813-98-3

sodium 2,4,5-trimethoxybenzoate

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

Conditions
ConditionsYield
With palladium diacetate; Tetrabutylammonium hydrogen diacetate; tricyclohexylphosphine In 1,2-dimethoxyethane at 120℃; for 24h; Inert atmosphere;8 %Chromat.
1,1-Diphenylmethanol
91-01-0

1,1-Diphenylmethanol

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

diphenyl(2,4,5-trimethoxyphenyl)methane

diphenyl(2,4,5-trimethoxyphenyl)methane

Conditions
ConditionsYield
With o-benzenedisulfonimide In neat (no solvent) at 20℃; for 1.5h; Friedel-Crafts Alkylation;100%
With 2C2H6O2*ZnCl2 at 90℃; for 1h; Temperature; Reagent/catalyst; Friedel-Crafts Alkylation;85%
With hydrogenchloride; ethanol
1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

1,2,4-trimethoxy-5-nitrobenzene
14227-14-6

1,2,4-trimethoxy-5-nitrobenzene

Conditions
ConditionsYield
With Nitrogen dioxide In dichloromethane in the dark; -78 deg C, 2 min; RT, 15 min;100%
With tert.-butylnitrite In acetonitrile at 20℃; for 1h;95%
With 3-(ethoxycarbonyl)-1-(5-methyl-5-(nitrosooxy)hexyl)pyridin-1-ium bis(trifluoromethanesulfonyl)imide at 20℃; for 2h; Ionic liquid;93%
1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

1-iodo-2,4,5-trimethoxybenzene
23149-33-9

1-iodo-2,4,5-trimethoxybenzene

Conditions
ConditionsYield
With iodine; silver trifluoroacetate In dichloromethane at 0℃; for 8h;100%
With N-iodo-succinimide; trifluoroacetic acid In acetonitrile at 20℃; for 0.1h;99%
With N-iodo-succinimide In acetonitrile at 20℃; for 16h; Inert atmosphere; Schlenk technique;99%
1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

1-bromo-2,4,5-trimethoxybenzene
20129-11-7

1-bromo-2,4,5-trimethoxybenzene

Conditions
ConditionsYield
With poly(4-vinylpyridine)-supported bromate; potassium bromide In acetonitrile for 5h;100%
With bromine In dichloromethane at 0℃;100%
With benzyltriphenylphosphonium peroxodisulfate; potassium bromide In acetonitrile for 2.5h; Heating;100%
1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

4-nitrobenzaldehdye
555-16-8

4-nitrobenzaldehdye

1,1'-[(4-nitrophenyl)methanediyl]bis(2,4,5-trimethoxybenzene)
54921-89-0

1,1'-[(4-nitrophenyl)methanediyl]bis(2,4,5-trimethoxybenzene)

Conditions
ConditionsYield
With o-benzenedisulfonimide at 130℃; for 0.25h; Friedel Crafts alkylation;100%
With air; iodine In toluene at 20℃; for 72h; Friedel Crafts alkylation;99%
With niobium pentachloride In dichloromethane at 0 - 20℃; for 24h; Friedel-Crafts Alkylation;98%
1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

methyl iodide
74-88-4

methyl iodide

2,3,6-trimethoxytoluene
25576-97-0

2,3,6-trimethoxytoluene

Conditions
ConditionsYield
Stage #1: 1,2,4-trimethoxy-benzene With n-butyllithium
Stage #2: methyl iodide
100%
Stage #1: 1,2,4-trimethoxy-benzene With n-butyllithium In tetrahydrofuran; hexane at -78 - 20℃; for 1h; Inert atmosphere;
Stage #2: methyl iodide In tetrahydrofuran; hexane for 1h; Inert atmosphere;
99%
Stage #1: 1,2,4-trimethoxy-benzene With n-butyllithium In tetrahydrofuran; hexane at -78 - 20℃; for 1.33333h; Inert atmosphere;
Stage #2: methyl iodide In tetrahydrofuran; hexane at -78 - 20℃; for 2h; Inert atmosphere;
99%
1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

4,4'-Dimethoxybenzhydrol
728-87-0

4,4'-Dimethoxybenzhydrol

bis(4-methoxyphenyl)(2,4,5-trimethoxyphenyl)methane
1562305-57-0

bis(4-methoxyphenyl)(2,4,5-trimethoxyphenyl)methane

Conditions
ConditionsYield
With o-benzenedisulfonimide In neat (no solvent) at 20℃; for 0.25h; Friedel-Crafts Alkylation;100%
1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

C9H10(2)H2O3

C9H10(2)H2O3

Conditions
ConditionsYield
With perchloric acid; d(4)-methanol at 75℃; for 15h; Inert atmosphere;100%
formaldehyd
50-00-0

formaldehyd

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

bis(2,4,5-trimethoxyphenyl)methane
30038-32-5

bis(2,4,5-trimethoxyphenyl)methane

Conditions
ConditionsYield
With trifluorormethanesulfonic acid In acetonitrile at 0 - 20℃; for 1h; Friedel-Crafts Alkylation;99%
With 1-methyl-3-(propyl-3-sulfonyl)imidazolium trifluoromethanesulfonate In neat (no solvent) at 40℃; for 0.5h; Friedel-Crafts Alkylation; Green chemistry;99%
With sulfuric acid; acetic acid
1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

benzaldehyde
100-52-7

benzaldehyde

1,1'-(phenylmethanediyl)bis(2,4,5-trimethoxybenzene)
54921-86-7

1,1'-(phenylmethanediyl)bis(2,4,5-trimethoxybenzene)

Conditions
ConditionsYield
With 1-methyl-3-(propyl-3-sulfonyl)imidazolium trifluoromethanesulfonate In neat (no solvent) at 40℃; for 0.5h; Catalytic behavior; Reagent/catalyst; Temperature; Friedel-Crafts Alkylation; Green chemistry;99%
With boron trifluoride diethyl etherate In dichloromethane at 20℃; for 0.0833333h; Friedel-Crafts Alkylation;95%
With o-benzenedisulfonimide at 130℃; for 3.5h; Friedel Crafts alkylation; neat (no solvent);93%
1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

2,3,5,6-tetramethyl-4-oxo-1-phenylthiocyclohexa-2,5-dienyl 2-chloroacetate
194720-38-2

2,3,5,6-tetramethyl-4-oxo-1-phenylthiocyclohexa-2,5-dienyl 2-chloroacetate

A

1,2,4-trimethoxy-5-phenylsulfanylbenzene

1,2,4-trimethoxy-5-phenylsulfanylbenzene

B

4-hydroxy-2,3,5,6-tetramethylphenyl 2-chloroacetate

4-hydroxy-2,3,5,6-tetramethylphenyl 2-chloroacetate

Conditions
ConditionsYield
With trimethylsilyl trifluoromethanesulfonate In acetonitrile for 0.166667h; Yields of byproduct given;A 99%
B n/a
1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

2,3,5,6-tetramethyl-4-oxo-1-phenylthiocyclohexa-2,5-dienyl 2-chloroacetate
194720-38-2

2,3,5,6-tetramethyl-4-oxo-1-phenylthiocyclohexa-2,5-dienyl 2-chloroacetate

1,2,4-trimethoxy-5-phenylsulfanylbenzene

1,2,4-trimethoxy-5-phenylsulfanylbenzene

Conditions
ConditionsYield
With trimethylsilyl trifluoromethanesulfonate In acetonitrile at -30 - 20℃; for 0.166667h;99%
2-Phenylpropanal
34713-70-7

2-Phenylpropanal

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

C27H32O6
1195735-85-3

C27H32O6

Conditions
ConditionsYield
With air; iodine In toluene at 20℃; for 130h; Friedel Crafts alkylation;99%
1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

4-chlorobenzaldehyde
104-88-1

4-chlorobenzaldehyde

1,1'-[(4-chlorophenyl)methanediyl]bis(2,4,5-trimethoxybenzene)
1190880-27-3

1,1'-[(4-chlorophenyl)methanediyl]bis(2,4,5-trimethoxybenzene)

Conditions
ConditionsYield
With niobium pentachloride In dichloromethane at 0 - 20℃; for 24h; Friedel-Crafts Alkylation;99%
With 1-methyl-3-(propyl-3-sulfonyl)imidazolium trifluoromethanesulfonate In neat (no solvent) at 40℃; for 0.5h; Friedel-Crafts Alkylation; Green chemistry;91%
With silica supported o-benzenedisulfonimide at 20℃; for 1.25h; Friedel Crafts alkylation; neat (no solvent);90%
With air; iodine In toluene at 20℃; for 72h; Friedel Crafts alkylation;88%
1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

cyclohexanecarbaldehyde
2043-61-0

cyclohexanecarbaldehyde

5,5'-(cyclohexylmethylene)bis(1,2,4-trimethoxybenzene)
1195735-86-4

5,5'-(cyclohexylmethylene)bis(1,2,4-trimethoxybenzene)

Conditions
ConditionsYield
With air; iodine In toluene at 20℃; for 72h; Friedel Crafts alkylation;99%
With trifluorormethanesulfonic acid In acetonitrile at 0 - 20℃; for 24h; Friedel-Crafts Alkylation;83%
6-bromohexanoyl chloride
22809-37-6

6-bromohexanoyl chloride

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

6-bromo-1-(2,4,5-trimethoxyphenyl)hexan-1-one
1268333-97-6

6-bromo-1-(2,4,5-trimethoxyphenyl)hexan-1-one

Conditions
ConditionsYield
With aluminum (III) chloride In dichloromethane at -10 - 20℃; Friedel Crafts Acylation;99%
3-pyridinecarboxaldehyde
500-22-1

3-pyridinecarboxaldehyde

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

3-[bis(2,4,5-trimethoxyphenyl)methyl]pyridine
1431862-12-2

3-[bis(2,4,5-trimethoxyphenyl)methyl]pyridine

Conditions
ConditionsYield
With trifluorormethanesulfonic acid In acetonitrile at 0 - 20℃; for 24h; Friedel-Crafts Alkylation;99%
1-(4-methoxyphenyl)but-3-en-1-ol
24165-60-4

1-(4-methoxyphenyl)but-3-en-1-ol

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

1,2,4-trimethoxy-5-[1-(4-methoxyphenyl)but-3-en-1-yl]benzene
1431862-22-4

1,2,4-trimethoxy-5-[1-(4-methoxyphenyl)but-3-en-1-yl]benzene

Conditions
ConditionsYield
With trifluorormethanesulfonic acid In acetonitrile at 0 - 20℃; for 0.75h;99%
1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

triethyl phosphite
122-52-1

triethyl phosphite

diethyl (2,4,5-trimethoxyphenyl)phosphonate

diethyl (2,4,5-trimethoxyphenyl)phosphonate

Conditions
ConditionsYield
With ammonium peroxydisulfate; tris(2,2′-bipyrazine-N1,N1′)ruthenium(II) hexafluorophosphate In acetonitrile at 25℃; for 20h; Catalytic behavior; Reagent/catalyst; Inert atmosphere; Irradiation;99%
1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

trimethyl orthoformate
149-73-5

trimethyl orthoformate

tris(2,4,5-trimethoxyphenyl)methane
14470-07-6

tris(2,4,5-trimethoxyphenyl)methane

Conditions
ConditionsYield
With bismuth(lll) trifluoromethanesulfonate In neat liquid at 20℃; for 3h; Catalytic behavior; Reagent/catalyst; Solvent; Temperature; Friedel-Crafts Alkylation;99%
1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

2,2',4,4',5,5'-hexamethoxybiphenyl
1702-67-6

2,2',4,4',5,5'-hexamethoxybiphenyl

Conditions
ConditionsYield
With molybdenum(V) chloride In dichloromethane at 20℃; for 0.5h;98%
With boron trifluoride diethyl etherate; bis-[(trifluoroacetoxy)iodo]benzene In dichloromethane at -40℃; for 1.5h;92%
With iron(III) chloride on silica In dichloromethane Product distribution; Mechanism; variation of conditions, other dimethoxyaryls;89%
1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

3-nitro-benzaldehyde
99-61-6

3-nitro-benzaldehyde

1,1′-[(3-nitrophenyl)methanediyl]bis(2,4,5-trimethoxybenzene)
54921-75-4

1,1′-[(3-nitrophenyl)methanediyl]bis(2,4,5-trimethoxybenzene)

Conditions
ConditionsYield
With niobium pentachloride In dichloromethane at 0 - 20℃; for 24h; Friedel-Crafts Alkylation;98%
With PEG-400 at 50 - 60℃; for 2h; Friedel-Crafts Alkylation; Green chemistry;95%
With hydrogenchloride; acetic acid
1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

4-fluorobenzaldehyde
459-57-4

4-fluorobenzaldehyde

1,1'-[(4-fluorophenyl)methanediyl]bis(2,4,5-trimethoxybenzene)
1195735-76-2

1,1'-[(4-fluorophenyl)methanediyl]bis(2,4,5-trimethoxybenzene)

Conditions
ConditionsYield
With niobium pentachloride In dichloromethane at 0 - 20℃; for 24h; Friedel-Crafts Alkylation;98%
With air; iodine In toluene at 20℃; for 72h; Friedel Crafts alkylation;97%
With 1-methyl-3-(propyl-3-sulfonyl)imidazolium trifluoromethanesulfonate In neat (no solvent) at 40℃; for 1h; Friedel-Crafts Alkylation; Green chemistry;92%
1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

4-bromo-benzaldehyde
1122-91-4

4-bromo-benzaldehyde

1,1'-[(4-bromophenyl)methanediyl]bis(2,4,5-trimethoxybenzene)
1195735-78-4

1,1'-[(4-bromophenyl)methanediyl]bis(2,4,5-trimethoxybenzene)

Conditions
ConditionsYield
With air; iodine In toluene at 20℃; for 72h; Friedel Crafts alkylation;98%
With trifluorormethanesulfonic acid In acetonitrile at 0 - 20℃; for 24h; Friedel-Crafts Alkylation;96%
With niobium pentachloride In dichloromethane at 0 - 20℃; for 24h; Friedel-Crafts Alkylation;96%
difluoromethyl phenyl sulfide
1535-67-7

difluoromethyl phenyl sulfide

1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

asaraldehyde
4460-86-0

asaraldehyde

Conditions
ConditionsYield
Stage #1: difluoromethyl phenyl sulfide; 1,2,4-trimethoxy-benzene With tin(IV) chloride In dichloromethane at 20℃; for 2h; Inert atmosphere;
Stage #2: With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In dichloromethane; water; dimethyl sulfoxide at 20℃; for 2h;
98%
1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

prenyl bromide
870-63-3

prenyl bromide

1,2,4-trimethoxy-3-(3-methylbut-2-en-1-yl)benzene

1,2,4-trimethoxy-3-(3-methylbut-2-en-1-yl)benzene

Conditions
ConditionsYield
Stage #1: 1,2,4-trimethoxy-benzene With n-butyllithium In tetrahydrofuran at 0℃; for 1h; Inert atmosphere;
Stage #2: prenyl bromide In tetrahydrofuran at 20℃; for 12h; Inert atmosphere;
98%
1,2,4-trimethoxy-benzene
135-77-3

1,2,4-trimethoxy-benzene

3,4,5-trimethoxy-benzaldehyde
86-81-7

3,4,5-trimethoxy-benzaldehyde

1,1'-[(3,4,5-trimethoxyphenyl)methanediyl]bis(2,4,5-trimethoxybenzene)
54921-97-0

1,1'-[(3,4,5-trimethoxyphenyl)methanediyl]bis(2,4,5-trimethoxybenzene)

Conditions
ConditionsYield
With niobium pentachloride In dichloromethane at 0 - 20℃; for 24h; Friedel-Crafts Alkylation;98%

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