2,4-Dinitrophenylhydrazine supplier

Name
2,4-Dinitrophenylhydrazine
EINECS 204-309-3
CAS No. 119-26-6
Article Data43
CAS DataBase
Density 1.655 g/cm³
Solubility slightly soluble in water
Melting Point 197-200 °C(lit.)
Formula C₆H₆N₄O₄
Boiling Point 378.603 °C at 760 mmHg
Molecular Weight 198.138
Flash Point 182.773 °C
Transport Information UN 3380 4.1/PG 1
Appearance white to light yellow crystal powder
Safety 35-48A-45-36/37-16
Risk Codes 1-11-22-40
Molecular Structure
Hazard Symbols F, Xn
Synonyms 2,4-dinitro-3,5,6-trideuterophenylhydrazine;2,4-dinitrophenylhydrazine
PSA 129.69000
LogP 2.60830

Synthetic route

: 97-00-7
1-chloro-2,4-dinitro-benzene

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
With pyrographite; hydrazine hydrate In ethanol for 1.16667h; Time; Reflux;	100%
With hydrazine hydrate In ethanol for 3.5h; Reflux;	91%
With ammonium hydroxide; hydrazine hydrate

: 100-63-0
phenylhydrazine

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
With bismuth (III) nitrate pentahydrate; palladium diacetate In 2,2,2-trifluoroethanol; trifluoroacetic acid at 20 - 90℃; for 24h; Inert atmosphere;	69%

: 610-54-8
2,4-dinitro-1-ethoxybenzene

A: 136-79-8
2-Amino-4-nitroethoxybenzen

B: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
With nickel; hydrazine hydrate In ethanol; 1,2-dichloro-ethane at 50 - 60℃; for 4h;	A 6% B n/a

: 2831-60-9
2-(2,4-dinitrophenoxy)ethanol

A: 59820-37-0
2-(2-amino-4-nitro-phenoxy)-ethanol

B: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
With nickel; hydrazine hydrate In ethanol; 1,2-dichloro-ethane at 50 - 60℃; for 4h;	A 1% B n/a

: 10242-16-7
2,4-dinitrophenyl isopropyl ether

A: 53965-13-2
2-isopropoxy-5-nitro-aniline

B: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
With nickel; hydrazine hydrate In ethanol; 1,2-dichloro-ethane at 50 - 60℃; for 4h;	A 1% B n/a

: 67674-33-3
2,4-dinitrophenyl 2-methoxyethyl ether

A: 63810-54-8
2-(2-methoxy-ethoxy)-5-nitro-aniline

B: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
With nickel; hydrazine hydrate In ethanol; 1,2-dichloro-ethane at 50 - 60℃; for 4h;	A 1% B n/a

: 40742-19-6
3-(2,4-dinitro-phenoxy)-propane-1,2-diol

A: 88964-89-0
3-(2-amino-4-nitro-phenoxy)-propane-1,2-diol

B: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
With nickel; hydrazine hydrate In ethanol; 1,2-dichloro-ethane at 50 - 60℃; for 3h;	A 1% B n/a

: 2486-07-9
2,4-dinitrophenyl phenyl ether

A: 5410-98-0
5-nitro-2-phenoxy-aniline

B: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
With nickel; hydrazine hydrate In ethanol; 1,2-dichloro-ethane at 50 - 60℃; for 3h;	A 0.5% B n/a

: 584-48-5
2,4-dinitrobromobenzene

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
With ethanol; hydrazine hydrate

: 119-27-7
2,4-dinitroanisole

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
With ethanol; hydrazine hydrate
With ethanol; hydrazine hydrate; acetic acid

: 2486-07-9
2,4-dinitrophenyl phenyl ether

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
With ethanol; hydrazine hydrate
With hydrazine hydro-chloride In water; dimethyl sulfoxide at 25℃; Kinetics;

: 2486-09-1
2,4-dinitro-1-phenylsulfanyl-benzene

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
With ethanol; hydrazine hydrate

: 1656-44-6
2,4-dinitrobenzenesulfonyl chloride

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
With N,N-dimethyl-formamide; hydrazine
With ethanol; hydrazine hydrate; benzene

: 67516-66-9
(2,4-dinitrophenyl)(phenyl)selane

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
With ethanol; hydrazine hydrate

: 7335-65-1
hydrazinium monoacetate

: 97-00-7
1-chloro-2,4-dinitro-benzene

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
With ethanol

: 696-59-3
cis,trans-2,5-dimethoxytetrahydrofuran

A: 123217-87-8
Carbazol-9-yl-(2,4-dinitro-phenyl)-amine

B: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
With hydrogenchloride In ethanol for 3h; Heating; molar ratio 1:2;

: 67175-84-2
N-Methyl-6-ketooctahydroindol

: 114634-46-7
N-(2,4-Dinitro-phenyl)-N'-[1-methyl-octahydro-indol-(6E)-ylidene]-hydrazine

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
Yield given;

: 70-34-8
2,4-Dinitrofluorobenzene

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
With hydrazine In methanol; water at 25℃; Rate constant; pH 8.00 to 10.00, ionic strength of 0.1 mol l-1;
With potassium chloride; hydrazine In water; acetonitrile at 25℃; pH=8.4; Kinetics; pH-value;
Multi-step reaction with 2 steps 1: sodium ethanolate / ethanol 2: hydrazine hydro-chloride / dimethyl sulfoxide; water / 25 °C View Scheme

: 42216-75-1
succindialdehyde bis-2,4-dinitrophenylhydrazone

A: 4815-51-4
(2,4-Dinitro-phenyl)-pyrrol-1-yl-amine

B: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
With hydrogenchloride In ethanol for 0.5h; Heating;

: 1157-84-2
1-benzylidene-2-(2,4-dinitrophenyl)hydrazone

A: 100-52-7
benzaldehyde

B: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
With hydrogenchloride In water; acetone at 30℃; Rate constant; Thermodynamic data; Ea, ΔH(excit.), ΔS(excit.), ΔG(excit.);

: 1160-77-6
N-(2,4-dinitrophenyl)-N'-(3'-hydroxybenzylidene)hydrazone

A: 100-83-4
meta-hydroxybenzaldehyde

B: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
With hydrogenchloride In water; acetone at 30℃; Rate constant; Thermodynamic data; Ea, ΔH(excit.), ΔS(excit.), ΔG(excit.);

: 1160-78-7
4-hydroxy-benzaldehyde-(2,4-dinitro-phenylhydrazone)

A: 123-08-0
4-hydroxy-benzaldehyde

B: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
With hydrogenchloride In water; acetone at 30℃; Rate constant; Thermodynamic data; Ea, ΔH(excit.), ΔS(excit.), ΔG(excit.);

: 1160-76-5
salicylaldehyde 2,4-dinitrophenylhydrazone

A: 90-02-8
salicylaldehyde

B: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

Conditions

Conditions	Yield
With hydrogenchloride In water; acetone at 30℃; Rate constant; Thermodynamic data; Ea, ΔH(excit.), ΔS(excit.), ΔG(excit.);

: 1567-89-1
N-(2,4-dinitrophenyl)-N'-isopropylidene-hydrazine

strong hydrochloric acid: strong hydrochloric acid

A: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

B: 67-64-1
acetone

...Expand

: 64-17-5
ethanol

: 119-27-7
2,4-dinitroanisole

: 7803-57-8
hydrazine hydrate

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

...Expand

: 64-17-5
ethanol

: 2486-07-9
2,4-dinitrophenyl phenyl ether

: 7803-57-8
hydrazine hydrate

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

...Expand

: sodium bis(2,4-dinitrophenyl) phosphate

A: 20350-26-9
2,4-dinitrophenolate

B: 18962-96-4
2,4-dinitrophenyl phosphate dianion

C: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

D: C6H5N4O7P(2-)

Conditions

Conditions	Yield
In water at 25℃; pH=10; Kinetics;

...Expand

: 103-72-0
phenyl isothiocyanate

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 105394-88-5
2-(2',4'-dinitrophenyl)-N-phenyl-1-hydrazinecarbothioamide

Conditions

Conditions	Yield
at 20℃;	100%
With ethanol
In ethanol Heating;

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 598-31-2
1-bromoacetone

: 93282-21-4
1-(1-bromopropan-2-yl)-2-(2,4-dinitrophenyl) hydrazine

Conditions

Conditions	Yield
In ethyl acetate for 0.5h; Heating;	100%
With acetic acid In ethanol	66%

: 816-39-7
1,3-dibromoroacetone

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 98590-53-5
dibromoacetone 2,4-dinitrophenylhydrazone

Conditions

Conditions	Yield
In ethyl acetate for 0.5h; Heating;	100%

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 1-ethylthio-2,4-diphenylphthalazinium tetrafluoroborate

: 1-(2,4-dinitrophenylhydrazono)-2-phenyl-4-phenyl-1,2-dihydrophthalazine

Conditions

Conditions	Yield
With acetic acid; triethylamine	100%

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 1-ethylthio-2-phenyl-4-p-tolylphthalazinium tetrafluoroborate

: 1-(2,4-dinitrophenylhydrazono)-2-phenyl-4-tolyl-1,2-dihydrophthalazine

Conditions

Conditions	Yield
With acetic acid; triethylamine	100%

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 1-ethylthio-2-phenyl-4-(p-chlorophenyl)phthalazinium tetrafluoroborate

: 1-(2,4-dinitrophenylhydrazono)-2-phenyl-4-p-chlorophenyl-1,2-dihydrophthalazine

Conditions

Conditions	Yield
With acetic acid; triethylamine	100%

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 1-[(1R,4S)-2-(2-Methyl-propenyl)-4-(toluene-4-sulfonyl)-cyclobutyl]-ethanone

: N-(2,4-dinitro-phenyl)-N'-{1-[2-(2-methyl-propenyl)-4-(toluene-4-sulfonyl)-cyclobutyl]-ethylidene}-hydrazine

Conditions

Conditions	Yield
With hydrogenchloride In methanol at 45℃; for 0.25h; Condensation;	100%

: 888028-97-5
(R)-(-)-1-{5-[3-(2-thienyl)-3-hexyl]-2-thienyl}ethanone

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: (R)-1-{5-[3-(2-thienyl)-3-hexyl]-2-thienyl}ethanone 2,4-dinitrophenylhydrazone

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In methanol at 20℃;	100%

: C14H11ClO

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 4251-66-5
4-chlorophenylacetaldehyde 2,4-dinitrophenylhydrazone

Conditions

Conditions	Yield
With sulfuric acid In ethanol; water	100%

: C14H11NO3

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 3756-36-3
4-nitrophenylacetaldehyde 2,4-dinitrophenylhydrazone

Conditions

Conditions	Yield
With sulfuric acid In ethanol; water	100%

: 39153-68-9, 66694-17-5, 32546-83-1
(E,Z)-β-phenoxystyrene

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 2074-04-6
phenylacetaldehyde-2,4-dinitrophenylhydrazone

Conditions

Conditions	Yield
With sulfuric acid In ethanol; water	100%

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 349647-31-0
1-Bromo-4-((E)-2-phenoxy-vinyl)-benzene

: 4410-17-7
1-(2-(4-bromophenyl)ethylidene)-2-(2,4-dinitrophenyl)hydrazine

Conditions

Conditions	Yield
With sulfuric acid In ethanol; water	100%

: 124-13-0
Octanal

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: C14H20N4O4

Conditions

Conditions	Yield
	100%

: 104-53-0
3-phenyl-propionaldehyde

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 1237-68-9
(E)-1-(2,4-dinitrophenyl)-2-(3-phenylpropylidene)hydrazine

Conditions

Conditions	Yield
	100%
With sulfuric acid In ethanol; water for 0.5h; Inert atmosphere;
With hydrogenchloride In water for 1h; Inert atmosphere;	276 mg

: 10138-10-0
ethyl 4-oxobutanoate

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: C12H14N4O6

Conditions

Conditions	Yield
	100%

: (η5-cyclopentadienyl carboxaldehyde)rhenium tricarbonyl

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 76545-16-9
2,4-dinitrophenylhydrazonecyclopentadienyltricarbonylrhenium

Conditions

Conditions	Yield
In ethanol; sulfuric acid Ar; treatment of alc. soln. of (OC)3ReC5H4(CHO) with H2SO4 soln. of 2,4-dinitrophenylhydrazine (20°C); elem. anal.;	100%

: 1095432-76-0
2-formyl-[1,1'-biphenyl]-4,4'-dicarboxylic acid

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 1095432-82-8
C21H14N4O8

Conditions

Conditions	Yield
In 1,4-dioxane Reflux;	100%

: 1601497-22-6
4-methyl-2-phenyl-5,5,5-trifluoro-2(E)-pentenal

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 4-methyl-2-phenyl-5,5,5-trifluoropent-2(E)-enal (2,4-dinitrophenyl)hydrazone

Conditions

Conditions	Yield
With sulfuric acid In ethanol; water at 20℃; for 1.5h;	100%

: 4-(4-chlorophenyl)-3-cyano-5-ethanoylisoxazole

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 3-cyano-4-(4-chlorophenyl)-5-[1-(2,4-dinitrophenylhydrazino)ethyl]isoxazole

Conditions

Conditions	Yield
With hydrogenchloride In tetrahydrofuran; water for 1h; Reflux;	100%

: 175798-17-1
4-(6-Acryloyloxy-hexyloxy)-benzoic acid 4-formyl-phenyl ester

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: C29H28N4O9

Conditions

Conditions	Yield
In ethanol for 2h; Reflux;	100%

: 22105-09-5
4‐hydroxycoumarin

: 141-97-9
ethyl acetoacetate

: 555-16-8
4-nitrobenzaldehdye

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: C26H17N5O10

Conditions

Conditions	Yield
With 1-methyl-(3-trimethoxysilylpropyl)imidazolium chloride ionic-liquid functionalized magnetic iron oxide coated mesoporous hollow silica yolk-shell nanocomposite In ethanol; water at 70℃; for 0.416667h;	100%

...Expand

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 106-51-4
p-benzoquinone

: 16081-15-5
p-benzoquinone 2,4-dinitrophenylhydrazone

Conditions

Conditions	Yield
With carbon dioxide; water at 80℃; under 18751.5 Torr; for 3.5h;	99.95%
With hydrogenchloride In ethanol

: 513-86-0, 52217-02-4
3-hydroxy-2-butanon

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 35015-94-2
3-hydroxy-2-butanone-2,4-dinitrophenylhydrazone

Conditions

Conditions	Yield
With hydrogenchloride In acetonitrile at 60℃; for 1.5h;	99.7%
With ethyl acetate
With sulfuric acid at 20℃; for 0.0833333h;
With hydrogenchloride In water; dimethyl sulfoxide
With hydrogenchloride In water

: 64-18-6
formic acid

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 7474-09-1
N'-(2,4-dinitrophenyl)formohydrazide

Conditions

Conditions	Yield
With sodium formate at 20℃; for 0.33h; Neat (no solvent);	99%
With 2,2,4,4,6,6-hexachloro-1,3,5-triaza-2,4,6-triphosphorine In neat (no solvent) at 50℃; for 0.0833333h;	98%
With sulfonated rice husk ash In neat (no solvent) at 60℃; for 0.0666667h;	97%

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 123-54-6
acetylacetone

: 7474-11-5
1-(2,4-dinitrophenyl)-3,5-dimethylpyrazole

Conditions

Conditions	Yield
With Cu1.5PMo12O40 at 20℃; for 0.333333h; Green chemistry;	99%
In water; glycerol at 90℃; for 0.466667h; Green chemistry;	98%
With tetrafluoroboric acid; water In acetonitrile at 20℃; for 2h; Catalytic behavior; Reagent/catalyst; Solvent; Time;	95%

: 17455-13-9
18-crown-6 ether

: 90-02-8
salicylaldehyde

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 1160-76-5
salicylaldehyde 2,4-dinitrophenylhydrazone

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In ethanol Heating;	99%

...Expand

: 85468-48-0
N-(p-methoxybenzylidene)aminophthalimide

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 1773-49-5
(E)-1-(2,4-dinitrophenyl)-2-(4-methoxybenzylidene)hydrazine

Conditions

Conditions	Yield
In ethanol; water for 3h; Heating;	99%

: 81726-56-9
(7E)-8--7-octenal

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

A: 21190-30-7
N,N'-bis(4-cyanophenyl)hydrazine

B: 79058-63-2
Korksaeuredialdehyd-bis(2,4-dinitrophenylhydrazon)

Conditions

Conditions	Yield
With sulfuric acid In ethanol; water for 0.25h;	A 82% B 99%

...Expand

: 112055-19-3
tris-dimorpholinomethyl s-triazine

: 119-26-6
(2,4-dinitro-phenyl)-hydrazine

: 112055-21-7
C24H15N15O12

Conditions

Conditions	Yield
With hydrogenchloride In ethanol at 60℃;	99%

2,4-Dinitrophenylhydrazine Consensus Reports

Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

2,4-Dinitrophenylhydrazine Specification

The 2,4-Dinitrophenylhydrazine, with the CAS registry number 119-26-6, is also known as 1-Hydrazino-2,4-dinitrobenzene.It belongs to the product Chemical Reagent.Its EINECS number is 204-309-3. This chemical's molecular formula is C₆H₆N₄O₄ and molecular weight is 198.13. What's more,Its systematic name is (2,4-Dinitrophenyl)hydrazine.And it is Used for determination of serum transaminase valley - and c - grass substrate supporting reagents.

Physical properties about 2,4-Dinitrophenylhydrazine are:(1)ACD/LogP: 1.454; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.45; (4)ACD/LogD (pH 7.4): 1.45; (5)ACD/BCF (pH 5.5): 7.50; (6)ACD/BCF (pH 7.4): 7.50; (7)ACD/KOC (pH 5.5): 147.21; (8)ACD/KOC (pH 7.4): 147.29; (9)#Freely Rotating Bonds: 4 ; (10)Index of Refraction: 1.731; (11)Molar Refractivity: 47.856 cm³; (12)Molar Volume: 119.744 cm³; (13)Surface Tension: 87.6439971923828 dyne/cm; (14)Density: 1.655 g/cm³; (15)Flash Point: 182.773 °C; (16)Enthalpy of Vaporization: 62.652 kJ/mol; (17)Boiling Point: 378.603 °C at 760 mmHg; (18)Vapour Pressure: 0 mmHg at 25°C.

Preparation: 2,4-Dinitrophenylhydrazine can be prepared by hydrazine sulfate and 2,4-dinitrochlorobenzene.

The 2,4-Dinitrophenylhydrazine is Highly Flammable,Harmful. When you are using it, please be cautious about it as the following: (1)Explosive when dry; (2)Highly Flammable; (3)Harmful if swallowed; (4)Limited evidence of a carcinogenic effect; (5)This material and its container must be disposed of in a safe way; (6)In case of accident or if you feel unwell, seek medical advice immediately (show label where possible); (7)Wear suitable protective clothing; (8)Wear suitable gloves; (9)Keep away from sources of ignition-No smoking.

You can still convert the following datas into molecular structure:
(1)SMILES:c1cc(c(cc1[N+](=O)[O-])[N+](=O)[O-])NN;
(2)Std. InChI:InChI=1S/C6H6N4O4/c7-8-5-2-1-4(9(11)12)3-6(5)10(13)14/h1-3,8H,7H2;
(3)Std. InChIKey:HORQAOAYAYGIBM-UHFFFAOYSA-N.

The toxicity data of 2,4-Dinitrophenylhydrazine as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	450mg/kg (450mg/kg)		Cancer Research. Vol. 41, Pg. 1469, 1981.
rat	LD	oral	> 500mg/kg (500mg/kg)		National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 25, 1953.

Product Name

2,4-Dinitrophenylhydrazine

Synthetic route

2,4-Dinitrophenylhydrazine Consensus Reports

2,4-Dinitrophenylhydrazine Specification

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