2,5-DICHLOROPHENOL supplier

Name
2,5-Dichlorophenol
EINECS 209-520-4
CAS No. 583-78-8
Article Data65
CAS DataBase
Density 1.458 g/cm³
Solubility 3 g/L (20 °C) in water
Melting Point 54-57 °C(lit.)
Formula C₆H₄Cl₂O
Boiling Point 214.621 °C at 760 mmHg
Molecular Weight 163.003
Flash Point 99.969 °C
Transport Information UN 2020 6.1/PG 3
Appearance white to light brown crystals
Safety 26-36/37/39-45-61-37/39
Risk Codes 22-34-51/53-36/38
Molecular Structure
Hazard Symbols C, N, Xn
Synonyms 2,5-DCP;NSC 6296;
PSA 20.23000
LogP 2.69900

Synthetic route

: 1984-58-3
2,5-dichloroanisole

: 583-78-8
2,5-dichlorophenol

Conditions

Conditions	Yield
With hydrogenchloride; tetrabutylammomium bromide In water at 160℃; under 16501.7 Torr; for 5h; Temperature; Pressure; Reagent/catalyst; Autoclave; Large scale;	96.8%
With potassium hydroxide In water at 140℃; under 2625.26 Torr; for 18h; Reagent/catalyst; Pressure; Solvent; Temperature; Autoclave; Large scale;	96.5%

: 120-82-1
1,2,4-Trichlorobenzene

: 583-78-8
2,5-dichlorophenol

Conditions

Conditions	Yield
With sodium ethanolate; sodium phenylsulfonate at 190℃; under 21752.2 Torr; for 10h; Reagent/catalyst; Temperature; Pressure; Autoclave; Inert atmosphere;	92.6%
With sodium hydroxide In ethylene glycol at 180℃; for 3h; Temperature;	70.4%
With sodium hydroxide at 180 - 190℃;

: 95-82-9
2,5 dichloroaniline

: 583-78-8
2,5-dichlorophenol

Conditions

Conditions	Yield
With sulfuric acid; sodium nitrite In water	86%
Diazotization;
With sulfuric acid; sodium nitrite at 20℃; Diazotization.kochen mit Wasser;

: 1435-50-3
2-bromo-1,4-dichlorobenzene

: 583-78-8
2,5-dichlorophenol

Conditions

Conditions	Yield
With sodium hydroxide In methanol; water at 180℃; under 9000.9 - 9750.98 Torr; for 3h; Temperature; Pressure;	85.4%
With methanol; sodium methylate at 180℃;

: 1984-58-3
2,5-dichloroanisole

A: 583-78-8
2,5-dichlorophenol

B: 7051-13-0
1-chloro-2,4-dimethoxybenzene

Conditions

Conditions	Yield
With sodium methylate In N,N,N,N,N,N-hexamethylphosphoric triamide at 120℃;	A 83% B 8%

: 106-46-7
para-dichlorobenzene

: 583-78-8
2,5-dichlorophenol

Conditions

Conditions	Yield
With peracetic acid; acetic acid at 30 - 75℃; for 6.5h; Temperature; Reagent/catalyst;	80.9%
With vanadia; dihydrogen peroxide; acetic acid at 25 - 50℃; for 5.5h; Reagent/catalyst; Temperature;	78.2%
With dihydrogen peroxide; acetic acid at 90℃; Temperature;	41.9%

: 108-43-0
3-monochlorophenol

A: 583-78-8
2,5-dichlorophenol

B: 95-77-2
3,4-dichlorophenol

Conditions

Conditions	Yield
With N-chloro-succinimide; (R)-[1,1′-binaphthalene]-2,2′-diylbis-(diphenylphosphine sulfide) In chloroform-d1 at 20℃; for 2h; regioselective reaction;	A n/a B 71%
With N-chloro-succinimide; C24H20F12N4OS In chloroform-d1 at 20℃; for 5h; regioselective reaction;	A 76 %Spectr. B n/a

: 67-56-1
methanol

: 120-82-1
1,2,4-Trichlorobenzene

A: 583-78-8
2,5-dichlorophenol

B: 95-77-2
3,4-dichlorophenol

C: 553-82-2
1,3-dichloro-4-methoxybenzene

D: 1984-58-3
2,5-dichloroanisole

E: 120-83-2
2,4-dichlorophenol

F: 36404-30-5
3,4-dichloroanisole

Conditions

Conditions	Yield
With water; sodium hydroxide at 190℃; for 1.5h; Autoclave;	A 64.6% B n/a C n/a D n/a E n/a F n/a
With water; sodium hydroxide at 190℃; for 1.5h; Sealed tube; regioselective reaction;

...Expand

: 319-94-8
(36/45)-1,3,4,5,6-pentachlorocyclohexene

A: 591-35-5
3,5-dichlorophenol

B: 583-78-8
2,5-dichlorophenol

C: 95-77-2
3,4-dichlorophenol

D: 2,6-dichloro-2,5-cyclohexadiene-1,4-diol

: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol

: C6H6Cl4O

: C6H6Cl4O

: C6H7Cl3O2

Conditions

Conditions	Yield
With recombinant Sphingobium indicum B90A haloalkane dehalogenase LinB; water at 30℃; pH=7; aq. phosphate buffer; Enzymatic reaction;	A 0.7% B 13% C 0.7% D 3.7% E 17% F 62% G 0.9% H 1.4%

...Expand

: 305-15-7
(2,5-dichlorophenyl)hydrazine

A: 106-46-7
para-dichlorobenzene

B: 583-78-8
2,5-dichlorophenol

C: 4381-30-0
2-(2,5-dichlorophenyl)pyridine

D: 4467-14-5
4-(2,5-Dichloro-phenyl)-pyridine

Conditions

Conditions	Yield
With KO2 In pyridine for 10h; Ambient temperature; Further byproducts given;	A 59% B 2% C n/a D n/a

...Expand

: 1984-58-3
2,5-dichloroanisole

: 124-41-4
sodium methylate

A: 583-78-8
2,5-dichlorophenol

B: 7051-13-0
1-chloro-2,4-dimethoxybenzene

Conditions

Conditions	Yield
In N,N,N,N,N,N-hexamethylphosphoric triamide at 120℃; for 1h;	A n/a B 8%

...Expand

: 108-43-0
3-monochlorophenol

A: 583-78-8
2,5-dichlorophenol

B: 58802-21-4
2,8-dichlorodibenzofuran

C: 1,7-dichlorodibenzofuran

D: 1,9-dichlorodibenzofuran

Conditions

Conditions	Yield
With oxygen; silica gel; copper dichloride at 425℃; Formation of xenobiotics; Further byproducts.;	A 0.11% B 0.3679% C 2.9331% D 0.0698%

...Expand

: 108-43-0
3-monochlorophenol

A: 583-78-8
2,5-dichlorophenol

B: 58802-21-4
2,8-dichlorodibenzofuran

C: 58-90-2
2,3,4,6-tetrachlorophenol

D: 1,7-dichlorodibenzofuran

Conditions

Conditions	Yield
With oxygen; silica gel; copper dichloride at 400℃; Formation of xenobiotics; Further byproducts.;	A 0.128% B 0.0913% C 0.001% D 1.3967%

...Expand

: 108-43-0
3-monochlorophenol

A: 583-78-8
2,5-dichlorophenol

B: 95-77-2
3,4-dichlorophenol

C: 576-24-9
2,3-dichlorophenol

D: 1,7-dichlorodibenzofuran

Conditions

Conditions	Yield
With oxygen; silica gel; copper dichloride at 350℃; Formation of xenobiotics; Further byproducts.;	A 0.227% B 0.027% C 0.051% D 0.115%
With oxygen; silica gel; copper dichloride at 375℃; Formation of xenobiotics; Further byproducts.;	A 0.139% B 0.019% C 0.032% D 0.2629%

...Expand

: 108-43-0
3-monochlorophenol

A: 583-78-8
2,5-dichlorophenol

B: 95-77-2
3,4-dichlorophenol

C: 576-24-9
2,3-dichlorophenol

D: 95-95-4
2,4,5-trichlorophenol

Conditions

Conditions	Yield
With oxygen; silica gel; copper dichloride at 300℃; Product distribution; Further Variations:; Temperatures;	A 0.262% B 0.044% C 0.061% D 0.021%

...Expand

: 29682-41-5
2,5-dichloroiodobenzene

: 124-41-4
sodium methylate

A: 106-46-7
para-dichlorobenzene

B: 583-78-8
2,5-dichlorophenol

C: 1984-58-3
2,5-dichloroanisole

Conditions

Conditions	Yield
at 180℃;

...Expand

: 29682-41-5
2,5-dichloroiodobenzene

: 583-78-8
2,5-dichlorophenol

Conditions

Conditions	Yield
With methanol; sodium methylate at 180℃;

: 348-59-4
1,4-dichloro-2-fluorobenzene

: 124-41-4
sodium methylate

: 583-78-8
2,5-dichlorophenol

: 348-59-4
1,4-dichloro-2-fluorobenzene

: 124-41-4
sodium methylate

A: 583-78-8
2,5-dichlorophenol

B: 1984-58-3
2,5-dichloroanisole

Conditions

Conditions	Yield
at 180℃;

...Expand

: 348-59-4
1,4-dichloro-2-fluorobenzene

: 583-78-8
2,5-dichlorophenol

Conditions

Conditions	Yield
With methanol; sodium methylate at 180℃;
With sodium methylate

: 28443-50-7
2-amino-5-chlorophenol

: 583-78-8
2,5-dichlorophenol

Conditions

Conditions	Yield
With hydrogenchloride Diazotization.Behandlung der Diazoniumsalz-Loesung mit CuCl in wss. HCl;

: 67-56-1
methanol

: 124-41-4
sodium methylate

: 120-82-1
1,2,4-Trichlorobenzene

: 583-78-8
2,5-dichlorophenol

Conditions

Conditions	Yield
at 180℃; im Rohr;

...Expand

: 124-41-4
sodium methylate

: 120-82-1
1,2,4-Trichlorobenzene

: 583-78-8
2,5-dichlorophenol

Conditions

Conditions	Yield
at 180℃;

: 90963-30-7
1-(2,5-dichlorophenoxy)silatrane

: 583-78-8
2,5-dichlorophenol

Conditions

Conditions	Yield
With sodium hydroxide In methanol; water at 24.9℃; Rate constant;

: 115142-05-7
uridine 3'-(2,5-dichlorophenyl) phosphate

A: 583-78-8
2,5-dichlorophenol

B: 606-02-0
uridine 2',3'-cyclic phosphate

Conditions

Conditions	Yield
1H-imidazole at 25℃; Rate constant; other catalyst;

: 30124-46-0
2,5-dichlorophenol acetate

: 109-73-9
N-butylamine

A: 1119-49-9
N-butylacetamide

B: 583-78-8
2,5-dichlorophenol

Conditions

Conditions	Yield
With (1,4,7,10-tetraoxacyclododecane) In chlorobenzene at 25℃; Rate constant; also with 18-crown-6;
In acetonitrile at 25℃; Kinetics;

...Expand

soil organic matter: soil organic matter

A: 87-65-0
2,6-Dichlorophenol

B: 583-78-8
2,5-dichlorophenol

C: 120-83-2
2,4-dichlorophenol

Conditions

Conditions	Yield
With sodium chloride for 8766h; Chlorination; Formation of xenobiotics;

...Expand

: 120-82-1
1,2,4-Trichlorobenzene

methanolic NaOH-solution: methanolic NaOH-solution

: 583-78-8
2,5-dichlorophenol

Conditions

Conditions	Yield
at 180 - 190℃;

: 120-82-1
1,2,4-Trichlorobenzene

steam: steam

copper /silica gel: copper /silica gel

: 583-78-8
2,5-dichlorophenol

Conditions

Conditions	Yield
at 500 - 600℃;

...Expand

: 120-82-1
1,2,4-Trichlorobenzene

steam: steam

iron /silica gel: iron /silica gel

: 583-78-8
2,5-dichlorophenol

Conditions

Conditions	Yield
at 500 - 600℃;

...Expand

: 583-78-8
2,5-dichlorophenol

: 106-96-7
propargyl bromide

: 15945-66-1
1,4-dichloro-2-(2-propynyloxy)benzene

Conditions

Conditions	Yield
With potassium carbonate In tetrahydrofuran	100%
With potassium carbonate In acetone; toluene at 20℃;
With potassium carbonate In acetone; toluene
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 24h;

: 583-78-8
2,5-dichlorophenol

: 146137-79-3
4-fluoro-3-formylbenzonitrile

: 1351861-89-6
C14H7Cl2NO2

Conditions

Conditions	Yield
With potassium carbonate In dimethyl sulfoxide at 50℃; for 4h;	100%
With potassium carbonate In dimethyl sulfoxide at 50℃; for 4h;	100%

: 583-78-8
2,5-dichlorophenol

: 107-30-2
chloromethyl methyl ether

: C8H8Cl2O2

Conditions

Conditions	Yield
Stage #1: 2,5-dichlorophenol With sodium hydride In tetrahydrofuran; mineral oil for 1h; Cooling with ice; Stage #2: chloromethyl methyl ether In tetrahydrofuran; mineral oil for 3h;	99.1%

: 583-78-8
2,5-dichlorophenol

: 1129-28-8
3-methoxycarbonylbenzyl bromide

: 1018446-56-4
methyl 3-[(2,5-dichlorophenoxy)methyl]benzoate

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 50℃;	99%

: 583-78-8
2,5-dichlorophenol

: 999-97-3
1,1,1,3,3,3-hexamethyl-disilazane

: 1,4-dichloro-2-(trimethylsilyloxy)benzene

Conditions

Conditions	Yield
at 170℃; for 1h;	98%

: 116-15-4
perfluoropropylene

: 583-78-8
2,5-dichlorophenol

: 1026364-35-1
1,1,2,3,3,3-hexafluoropropoxy-2,5-dichlorobenzene

Conditions

Conditions	Yield
With sodium hydroxide In dimethyl sulfoxide at 25℃; under 2250.23 Torr; Solvent; Reagent/catalyst; Temperature; Pressure;	97.7%

: 583-78-8
2,5-dichlorophenol

: 4489-34-3
4,6-dichloro-2-(methylsulfonyl)pyrimidine

: 4,6-dichloro-2-(2,5-dichlorophenoxy)pyrimidine

Conditions

Conditions	Yield
Stage #1: 2,5-dichlorophenol With sodium; sodium hydride In tetrahydrofuran at -50℃; for 0.333333h; Stage #2: 4,6-dichloro-2-(methylsulfonyl)pyrimidine In tetrahydrofuran at -50℃; for 2h;	97%

: 583-78-8
2,5-dichlorophenol

: 58479-61-1
tert-butylchlorodiphenylsilane

: C22H22Cl2OSi

Conditions

Conditions	Yield
Stage #1: 2,5-dichlorophenol With dmap In dichloromethane at -4℃; for 0.5h; Inert atmosphere; Stage #2: tert-butylchlorodiphenylsilane In dichloromethane at -4℃; Inert atmosphere;	96.8%

: 583-78-8
2,5-dichlorophenol

: 106-95-6
allyl bromide

: 116435-13-3
2-(allyloxy)-1,4-dichlorobenzene

Conditions

Conditions	Yield
Stage #1: 2,5-dichlorophenol With potassium carbonate In acetone at 20℃; for 0.166667h; Inert atmosphere; Stage #2: allyl bromide In acetone at 60℃; for 4h;	96%
With potassium carbonate In acetone at 20℃; for 16h;	94%
Stage #1: 2,5-dichlorophenol With potassium carbonate In acetone at 20℃; for 0.166667h; Inert atmosphere; Stage #2: allyl bromide In acetone at 60℃; for 4h; Inert atmosphere;

: 583-78-8
2,5-dichlorophenol

: 106-89-8
epichlorohydrin

: 21324-87-8
1-(2,5-dichloro-phenoxy)-2,3-epoxypropane

Conditions

Conditions	Yield
Stage #1: 2,5-dichlorophenol With potassium carbonate In acetonitrile at 80℃; for 0.5h; Stage #2: epichlorohydrin In acetonitrile	96%

: 583-78-8
2,5-dichlorophenol

: 13139-86-1
4-methoxyphenyl magnesium bromide

: 959995-20-1
4-chloro-4'-methoxy-[1,1'-biphenyl]-2-ol

Conditions

Conditions	Yield
With tricyclohexylphosphine; tris(dibenzylideneacetone)dipalladium (0) In tetrahydrofuran at 50℃; for 18h;	95%
With tris-(dibenzylideneacetone)dipalladium(0); tricyclohexylphosphine In tetrahydrofuran at 50℃; for 18h;	95%

: 583-78-8
2,5-dichlorophenol

: 369-34-6
3,4-difluoronitrobenzene

: 908380-84-7
1-(2,5-dichloro-phenoxy)-2-fluoro-4-nitro-benzene

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 150℃;	94.7%

: 583-78-8
2,5-dichlorophenol

: 51356-03-7
4,5-dichloro-2-chloromethyl-pyridazin-3(2H)-one

: 1174278-26-2
4-chloro-5-(2,5-dichlorophenoxy)-2-[(2,5-dichlorophenoxy)-methyl]pyridazin-3(2H)-one

Conditions

Conditions	Yield
With potassium carbonate In methanol for 12h; Reflux;	94%

: 583-78-8
2,5-dichlorophenol

: 100-39-0
benzyl bromide

: benzyl-(2,5-dichloro-phenyl)-ether

Conditions

Conditions	Yield
With potassium phosphate In N,N-dimethyl-formamide at 50℃; for 8h;	93.1%

: 583-78-8
2,5-dichlorophenol

: 108-24-7
acetic anhydride

: 30124-46-0
2,5-dichlorophenol acetate

Conditions

Conditions	Yield
In tetrahydrofuran at 60 - 80℃; for 1.5h;	92.8%
With lithium bis(perfluorooctylsulfonyl)amide at 40℃; for 40h; Catalytic behavior;	91%
With dmap; triethylamine In toluene for 8h; Heating;	85%
at 150℃;

: 583-78-8
2,5-dichlorophenol

: 1835-65-0
Tetrafluorophthalonitrile

: 238074-06-1
4,5-bis(2,5-dichlorophenoxy)-3,6-difluorophthalonitrile

Conditions

Conditions	Yield
With potassium fluoride In acetone at -5 - 0℃;	92.4%
With potassium fluoride In acetone at -1 - 20℃;	72.7%

: 583-78-8
2,5-dichlorophenol

A: 1940-42-7
4-bromo-2,5-dichlorophenol

B: 13664-63-6
2,4-dibromo-3,6-dichlorophenol

Conditions

Conditions	Yield
With N-Bromosuccinimide; hydrogen bromide In methanol; water for 2h; -20 deg C to room temperature.; Yields of byproduct given;	A n/a B 90.9%

: 583-78-8
2,5-dichlorophenol

: 100-00-5
4-chlorobenzonitrile

: 39145-48-7
1,4-dichloro-2-(4-nitrophenoxy)benzene

Conditions

Conditions	Yield
With potassium hydroxide; sodium hydroxide	88%

: 583-78-8
2,5-dichlorophenol

: 41103-17-7
ethyl 4-chloropyrimidine-5-carboxylate

: 1315469-71-6
ethyl 4-(2,5-dichlorophenoxy)pyrimidine-5-carboxylate

Conditions

Conditions	Yield
With caesium carbonate; tetrakis(actonitrile)copper(I) hexafluorophosphate In toluene for 2.5h; Reflux;	88%
With caesium carbonate; tetrakis(actonitrile)copper(I) hexafluorophosphate In toluene for 2.5h; Reflux;	88%
Stage #1: 2,5-dichlorophenol With sodium hydride In N,N-dimethyl-formamide for 0.5h; Cooling with ice; Stage #2: ethyl 4-chloropyrimidine-5-carboxylate In N,N-dimethyl-formamide at 20℃; for 2h;	55%

: 583-78-8
2,5-dichlorophenol

: 2446-83-5
di-isopropyl azodicarboxylate

A: 1940-42-7
4-bromo-2,5-dichlorophenol

B: 19740-72-8
bis(1-methylethyl) 1,2-hydrazinedicarboxylate

Conditions

Conditions	Yield
With ZrBr4 In dichloromethane at 20℃; for 8h;	A 87% B n/a

...Expand

: 492-37-5, 2328-24-7
hydratropic acid

: 583-78-8
2,5-dichlorophenol

: 1308678-98-9
2,5-dichlorophenyl 2-phenylpropanoate

Conditions

Conditions	Yield
Stage #1: hydratropic acid With dicyclohexyl-carbodiimide In dichloromethane for 0.25h; Inert atmosphere; Stage #2: 2,5-dichlorophenol In dichloromethane for 12h; Inert atmosphere;	87%

: 583-78-8
2,5-dichlorophenol

: 88-10-8
N,N-diethylcarbamyl chloride

: O-2,5-dichlorophenyl N,N-diethylcarbamate

Conditions

Conditions	Yield
Stage #1: 2,5-dichlorophenol With sodium hydroxide In tetrahydrofuran for 0.166667h; Stage #2: N,N-diethylcarbamyl chloride In tetrahydrofuran at 20℃; for 24h;	87%
Stage #1: 2,5-dichlorophenol With sodium hydroxide In tetrahydrofuran at 20℃; for 0.166667h; Inert atmosphere; Stage #2: N,N-diethylcarbamyl chloride In tetrahydrofuran at 20℃; for 24h; Inert atmosphere;

: 583-78-8
2,5-dichlorophenol

: 7587-15-7
2,3-dichloro-4-iodophenol

Conditions

Conditions	Yield
With silver(II) sulfate; iodine In dichloromethane for 24h;	86%
With iodine; silver sulfate In dichloromethane	56%
With iodine; silver sulfate; sodium thiosulfate In dichloromethane; water

: 583-78-8
2,5-dichlorophenol

: 187333-95-5
methyl (2R)-N-benzyloxycarbonylisoserinate

: methyl (2S)-3-{[(benzyloxy)carbonyl]amino}-2-(2,5-dichlorophenoxy)propanoate

Conditions

Conditions	Yield
With di-tert-butyl-diazodicarboxylate; triphenylphosphine In tetrahydrofuran at 20℃; for 18h;	86%

: 583-78-8
2,5-dichlorophenol

: 350-46-9
4-Fluoronitrobenzene

: 39145-48-7
1,4-dichloro-2-(4-nitrophenoxy)benzene

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 3h;	86%
With sodium carbonate In N,N-dimethyl-formamide at 170℃; for 1h; Microwave irradiation;

: 358-23-6
trifluoromethylsulfonic anhydride

: 583-78-8
2,5-dichlorophenol

: 556112-21-1
2,5-dichloro-1-trifluoromethanesulfonyloxybenzene

Conditions

Conditions	Yield
With pyridine at 0 - 20℃; for 22h;	85%
With pyridine In dichloromethane at 20℃;	77%

2,5-DICHLOROPHENOL Chemical Properties

Chemical Name: 2,5-Dichlorophenol
IUPAC NAME: 2,5-dichlorophenol
CAS No.: 583-78-8
EINECS: 209-520-4
RTECS: SK8600000
RTECS Class: Mutagen
EC Class: harmful, irritant
Molecular Formula: C₆H₄Cl₂O
Molecular Weight: 163 g/mol
Density: 1.458 g/cm³
Melting Point: 54-57 °C(lit.)
Flash Point: 100 °C
Boiling Point: 214.6 °C at 760 mmHg
Storage temp.: 0-6°C
Water Solubility: 3 g/L (20 °C )
The white prism crystal,2,5-DICHLOROPHENOL(583-78-8),is stable at room temperature in closed containers under normal storage and handling conditions,but incompatible with acid anhydrides, acid chlorides, strong oxidizing agents.It is slightly soluble in water, soluble in benzene, petroleum ether, ethanol, ethyl ethe.Following is the structure of 2,5-DICHLOROPHENOL(583-78-8):

The chemical synonymous of 2,5-DICHLOROPHENOL(583-78-8) are 2,5-dichloro-pheno;6-HYDROXY-1,4-DICHLOROBENZENE;2,5-DICHLORO-1-HYDROXY-BENZENE;2,5-DICHLOROPHENOL;2,5-DCP;DICHLOROPHENOL-2,5;Dichlorophenol,98%;2,5-DICHLOROPHENOL PESTANAL.

2,5-DICHLOROPHENOL Uses

2,5-DICHLOROPHENOL(583-78-8) is mainly used as a medicine, dye intermediates, nitrogenous fertilizer synergist, leather mildew, etc.and it is used as intermediates in organic synthesis.

2,5-DICHLOROPHENOL Production

Product Categories about 2,5-DICHLOROPHENOL(583-78-8) are Aromatic Phenols;Organics;Phenol&Thiophenol&Mercaptan;Phenoles and thiophenoles;Chlorine Compounds;Phenols;Alpha sort;D;DAlphabetic;DIA - DIC;Pesticides&Metabolites;Volatiles/ Semivolatiles;Organic Building Blocks;Oxygen Compounds.

2,5-DICHLOROPHENOL Toxicity Data With Reference

1.	sce-mus-ipr 210 mg/kg	JACTDZ Journal of the American College of Toxicology. 2 (2)(1983),249.
2.	orl-rat LD50:580 mg/kg	NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) PB85-143766 .
3.	orl-mus LD50:946 mg/kg	TOLED5 Toxicology Letters. 29 (1985),39.

mouse	LD50	oral	946mg/kg (946mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Toxicology Letters. Vol. 29, Pg. 39, 1985.
rat	LD50	oral	580mg/kg (580mg/kg)		National Technical Information Service. Vol. PB85-143766,

2,5-DICHLOROPHENOL Consensus Reports

Reported in EPA TSCA Inventory.

2,5-DICHLOROPHENOL Safety Profile

Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits toxic vapors of Cl⁻.
Hazard Codes:
    C: Corrosive
    N: Dangerous for the environment
     Xn: Harmful
Risk Statements about 2,5-DICHLOROPHENOL(583-78-8):
    R22 Harmful if swallowed.
    R34 Causes burns.
    R36/38: Irritating to eyes and skin.
    R51/53: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic
Safety Statements about 2,5-DICHLOROPHENOL(583-78-8):
    S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
    S61 Avoid release to the environment. Refer to special instructions / safety data sheets.
    S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
    S37/39: Wear suitable gloves and eye/face protection.

2,5-DICHLOROPHENOL Specification

1. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Do not store in metal containers.
2. Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.
3. Personal Protection: Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
4. Fire Fighting: Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. May polymerize explosively when involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Combustible material; may burn but does not ignite readily. Extinguishing media: Use agent most appropriate to extinguish fire. Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding quantities of water until well after fire is out.
5. Reactivity Profile: 2,5-Dichlorophenol(583-78-8) is incompatible with acid chlorides, acid anhydrides and oxidizing agents.

Product Name

2,5-Dichlorophenol

Synthetic route

2,5-DICHLOROPHENOL Chemical Properties

2,5-DICHLOROPHENOL Uses

2,5-DICHLOROPHENOL Production

2,5-DICHLOROPHENOL Toxicity Data With Reference

2,5-DICHLOROPHENOL Consensus Reports

2,5-DICHLOROPHENOL Safety Profile

2,5-DICHLOROPHENOL Specification

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