2-Morpholinoethanol supplier

Name
2-Morpholinoethanol
EINECS 210-734-5
CAS No. 622-40-2
Article Data69
CAS DataBase
Density 1.06 g/cm³
Solubility miscible with water
Melting Point -1 °C
Formula C₆H₁₃NO₂
Boiling Point 224.4 °C at 760 mmHg
Molecular Weight 131.175
Flash Point 99.4 °C
Transport Information
Appearance clear colourless to yellow liquid
Safety 26-36-37/39
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms 2-(4-Morpholino)ethylalcohol;2-(4-Morpholinyl)-1-ethanol;2-(4-Morpholinyl)ethanol;4-(2-Hydroxyethyl)morpholine;N-(2-Hydroxyethyl)morpholine;N-(b-Hydroxyethyl)morpholine;NSC1946;b-Morpholinoethanol;N-(2-Hydroxyethyl) Morpholine;4-Morpholineethanol;
PSA 32.70000
LogP -0.75120

Synthetic route

: 110-91-8
morpholine

: 107-21-1
ethylene glycol

: 622-40-2
2-(morpholin-4-yl)ethanol

Conditions

Conditions	Yield
With triphenylphosphine; ruthenium trichloride at 120℃; for 2h;	100%

: 110-91-8
morpholine

: 540-51-2
2-bromoethanol

: 622-40-2
2-(morpholin-4-yl)ethanol

Conditions

Conditions	Yield
at 80℃; for 72h;	85%
With potassium carbonate In acetonitrile for 3h; Reflux;	83%
With potassium carbonate In acetonitrile for 3h; Reflux;	83%

: 141-43-5
ethanolamine

: 111-44-4
3-oxa-1,5-dichloropentane

: 622-40-2
2-(morpholin-4-yl)ethanol

Conditions

Conditions	Yield
With sodium carbonate In acetonitrile for 48h; Heating;	83%
at 90 - 170℃;
With potassium carbonate at 120℃;
With ethanol; copper

: 3235-82-3
N-morpholylacetic acid ethyl ester

: 622-40-2
2-(morpholin-4-yl)ethanol

Conditions

Conditions	Yield
With sodium tetrahydroborate In methanol at 0 - 50℃; for 8h;	76.6%

: 110-91-8
morpholine

: 107-07-3
2-chloro-ethanol

: 622-40-2
2-(morpholin-4-yl)ethanol

Conditions

Conditions	Yield
With sodium hydroxide at 40 - 45℃;	67%
With acetone
With benzene

: 75-21-8
oxirane

: 110-91-8
morpholine

: 622-40-2
2-(morpholin-4-yl)ethanol

Conditions

Conditions	Yield
With water at 0℃;
With methanol

: 102-71-6
triethanolamine

: 622-40-2
2-(morpholin-4-yl)ethanol

Conditions

Conditions	Yield
With sulfuric acid at 160 - 170℃;
With cation exchanger at 160 - 220℃;
With sulfuric acid at 130 - 150℃; for 15h;

: 637-39-8
triethanolamine hydrochloride

A: 110-91-8
morpholine

B: 622-40-2
2-(morpholin-4-yl)ethanol

C: 1723-94-0
1,2-dimorpholylethane

D: 6425-39-4
2,2'-dimorpholinodiethyl ether

Conditions

Conditions	Yield
at 190 - 230℃;

...Expand

: 637-39-8
triethanolamine hydrochloride

: 622-40-2
2-(morpholin-4-yl)ethanol

Conditions

Conditions	Yield
at 200 - 205℃; under 40 Torr; anschliessend Erhitzen mit wss.-aethanol. KOH;
at 200 - 205℃; under 40 Torr;
at 280℃; under 7 Torr; anschliessend Erhitzen mit wss.-aethanol. KOH;

: 111-44-4
3-oxa-1,5-dichloropentane

: 622-40-2
2-(morpholin-4-yl)ethanol

Conditions

Conditions	Yield
With ammonium hydroxide at 65 - 80℃; under 2206.5 - 3677.5 Torr; anschliessend Behandeln mit wss. NaOH;

: 110-91-8
morpholine

: 107-21-1
ethylene glycol

A: 622-40-2
2-(morpholin-4-yl)ethanol

B: 1723-94-0
1,2-dimorpholylethane

Conditions

Conditions	Yield
With triphenylphosphine; ruthenium trichloride at 120℃; for 2h; Product distribution; other catalyst, also with THF, other phosphine, also at 220 degC;
With hydridochlorotris(triphenylphosphine)ruthenium(II) at 100℃; for 5.5h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With ruthenium trichloride at 120℃; for 2.5h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With Ru(CO)12; triphenylphosphine In tetrahydrofuran at 220℃; for 15h; Yield given;
With tris(triphenylphosphine)ruthenium(II) chloride at 100℃; for 2h; Product distribution; Mechanism; other diol; other secondary amines; other catalysts; var. temp. and reaction times;

...Expand

: 35855-10-8
methyl 2-morpholin-4-ylacetate

: 622-40-2
2-(morpholin-4-yl)ethanol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In tetrahydrofuran Heating;

: 141-43-5
ethanolamine

: 7460-82-4
diethylene glycol ditosylate

: 622-40-2
2-(morpholin-4-yl)ethanol

: 50594-07-5
phenyl-carbamic acid-(2-morpholino-ethyl ester); hydrochloride

A: 622-40-2
2-(morpholin-4-yl)ethanol

B: 124-38-9
carbon dioxide

C: 62-53-3
aniline

Conditions

Conditions	Yield
With sodium hydroxide In ethanol; water at 40℃; Rate constant; Thermodynamic data; var. temp., EA;

...Expand

: 34270-90-1
2,2'-diiodoethyl ether

: 7664-41-7
ammonia

: 622-40-2
2-(morpholin-4-yl)ethanol

: 555-77-1
tris-(2-chloro-ethyl)-amine

aqueous Na2CO3: aqueous Na2CO3

: 622-40-2
2-(morpholin-4-yl)ethanol

: 555-77-1
tris-(2-chloro-ethyl)-amine

KOH <0.05n>: KOH <0.05n>

: 622-40-2
2-(morpholin-4-yl)ethanol

: 110-91-8
morpholine

: 624-76-0
Iodoethanol

: 622-40-2
2-(morpholin-4-yl)ethanol

Conditions

Conditions	Yield
With potassium carbonate; sodium iodide In ethanol for 12h; Reflux;

: 102-71-6
triethanolamine

: 141-43-5
ethanolamine

A: 622-40-2
2-(morpholin-4-yl)ethanol

B: 111-42-2
2,2'-iminobis[ethanol]

Conditions

Conditions	Yield
With oxygen; zirconium(IV) oxide In water at 325℃; under 760.051 Torr; Product distribution / selectivity;

...Expand

: 6342-79-6
1,2-dimorpholinoethane-1,2-dione

A: 622-40-2
2-(morpholin-4-yl)ethanol

B: 51068-78-1
2-hydroxy-1-(morpholin-4-yl)ethan-1-one

C: 107-21-1
ethylene glycol

Conditions

Conditions	Yield
With hydrogen; Cu/Al2O3/SiO2 In methanol at 170℃; under 41254.1 Torr; for 16.5h; Autoclave;

...Expand

: 102-71-6
triethanolamine

A: 622-40-2
2-(morpholin-4-yl)ethanol

B: 6425-39-4
2,2'-dimorpholinodiethyl ether

Conditions

Conditions	Yield
With sulfuric acid at 130 - 200℃; for 15h; Temperature; Time;

: 622-40-2
2-(morpholin-4-yl)ethanol

: 89583-07-3
N-(2-bromoethyl)morpholine

Conditions

Conditions	Yield
With dibromotriphenylphosphorane In dichloromethane at 0 - 20℃;	100%
With phosphorus tribromide In dichloromethane at 0 - 45℃;	23.7%
With hydrogen bromide at 130℃;

: 622-40-2
2-(morpholin-4-yl)ethanol

: 95925-60-3
4-(2-hydroxyethyl)morpholine 4-oxide

Conditions

Conditions	Yield
With dihydrogen peroxide	100%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 448-19-1
4-fluoro-2-methoxy-1-nitrobenzene

: 342435-24-9
4-(2-(3-methoxy-4-nitrophenoxy)ethyl)morpholine

Conditions

Conditions	Yield
With potassium hydroxide; tetrabutylammomium bromide In water; toluene at 18 - 60℃; for 22h;	100%
With tetrabutylammomium bromide; water; potassium hydroxide In toluene at 60℃; for 18h;	98%
With benzyltriethylammonium bromide; potassium hydroxide In water; toluene at 60℃; for 24h;	42.4%
With tetrabutyl-ammonium chloride; potassium hydroxide In toluene at 60℃; for 24h;	42%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 106-41-2
4-bromo-phenol

: 836-59-9
1-bromo-4-(2-morpholinoethoxy)benzene

Conditions

Conditions	Yield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 110℃; for 17h; Mitsunobu Displacement; Inert atmosphere;	100%
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 20℃; for 2.16667h;

: 622-40-2
2-(morpholin-4-yl)ethanol

: 851728-86-4
ethyl 1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-hydroxy-1H-pyrazole-3-carboxylate

: 935259-86-2
1-(2-chlorophenyl)-5-(4-chlorophenyl)-3-ethoxycarbonyl-4-(2-morpholinoethoxy)-1H-pyrazole

Conditions

Conditions	Yield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 0 - 20℃;	100%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 62574-66-7
3-chlorosulfonyl-4-chlorobenzoyl chloride

: 1135370-76-1
2-(morpholin-4-yl)ethyl 4-chloro-3-chlorosulfonylbenzoate

Conditions

Conditions	Yield
In dichloromethane for 12h;	100%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 1169860-18-7
2-morpholin-4-yl-potassium ethoxide

Conditions

Conditions	Yield
With potassium In ethanol at 0℃; Product distribution / selectivity;	100%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 8-bromo-1-(3-((tert-butyldimethylsilyl)oxy)propyl)-7-(4-chlorobenzyl)-3-methyl-1H-purine-2,6(3H,7H)-dione

: 1-(3-((tert-butyldimethylsilyl)oxy)propyl)-7-(4-chlorobenzyl)-3-methyl-8-(2-morpholinoethoxy)-1H-purine-2,6(3H,7H)-dione

Conditions

Conditions	Yield
With sodium at 20℃; for 24h;	100%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 2339-78-8
1,2-dichloro-4-fluoro-5-nitrobenzene

: 4-[2-(4,5-dichloro-2-nitrophenoxy)ethyl]morpholine

Conditions

Conditions	Yield
Stage #1: 2-(morpholin-4-yl)ethanol With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.166667h; Stage #2: 1,2-dichloro-4-fluoro-5-nitrobenzene In tetrahydrofuran; mineral oil at 0℃; for 1h;	100%

: 622-40-2
2-(morpholin-4-yl)ethanol

: C24H29BrIN5O4

: C25H33BrN6O4

Conditions

Conditions	Yield
With copper(l) iodide; 1,10-Phenanthroline; caesium carbonate at 110℃; for 0.5h; Microwave irradiation;	100%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 221040-07-9
4-benzyloxy-2-fluoro-1-nitrobenzene

: 4-{2-[5-(benzyloxy)-2-nitrophenoxy]ethyl}morpholine

Conditions

Conditions	Yield
Stage #1: 2-(morpholin-4-yl)ethanol With sodium hydride In tetrahydrofuran; mineral oil at 20 - 30℃; for 1h; Stage #2: 4-benzyloxy-2-fluoro-1-nitrobenzene In tetrahydrofuran; mineral oil at 20℃; for 1h;	99.2%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 3,3-diphenylpropyl 4-(2-(1-morpholine)ethoxy)acetoacetate

Conditions

Conditions	Yield
	99%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 6-hydroxy-1-oxo-3-phenyl-1H-indene-2-carboxylic acid isopropyl amide

: 867187-72-2
6-(2-morpholine-4-ylethoxy)-1-oxo-3-phenyl-1H-indene-2-carboxylic acid isopropyl amide

Conditions

Conditions	Yield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran; benzene at 0 - 20℃; for 2h;	99%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 1655-07-8
ethyl 2-oxocyclohexane carboxylate

: C13H21NO4

Conditions

Conditions	Yield
In toluene for 120h; Reflux;	98%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 41288-96-4
6-chloropyridine-3-ol

: 879487-97-5
4-(2-((6-chloropyridin-3-yl)oxy)ethyl)morpholine

Conditions

Conditions	Yield
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 20℃; for 4h;	97%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 16004-15-2
1-bromomethyl-4-iodobenzene

: 4-(2-hydroxyethyl)-4-(4-iodobenzyl)morpholin-4-ium bromide

Conditions

Conditions	Yield
at 72℃; for 18h;	97%
In N,N-dimethyl-formamide at 72℃; Inert atmosphere;	97%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 95-16-9
1,3-Benzothiazole

: 26278-79-5
2-amino-6-hydroxybenzothiazole

: 1972-28-7
diethylazodicarboxylate

: 6-(2-morpholinoethoxy)benzo[d]thiazol-2-amine

Conditions

Conditions	Yield
With sodium hydrogencarbonate; triphenylphosphine In tetrahydrofuran; ethyl acetate	96%
With sodium hydrogencarbonate; triphenylphosphine In tetrahydrofuran; ethyl acetate	96%
With sodium hydrogencarbonate; triphenylphosphine In tetrahydrofuran; ethyl acetate	96%

...Expand

: 622-40-2
2-(morpholin-4-yl)ethanol

: 400-74-8
2-Fluoro-5-nitrobenzotrifluoride

: 850797-92-1
4-[2-(4-nitro-2-trifluoromethyl-phenoxy)-ethyl]-morpholine

Conditions

Conditions	Yield
Stage #1: 2-(morpholin-4-yl)ethanol With potassium tert-butylate In tetrahydrofuran at 20℃; for 0.5h; Stage #2: 2-Fluoro-5-nitrobenzotrifluoride In tetrahydrofuran at 20℃; for 4h;	96%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 910912-09-3
8,8′,8″-(hydroxymethanetriyl)tris[2,2,6,6-tetramethylbenzo[1,2-d:4,5-d′]bis([1,3]dithiole)-4-carboxylic acid]

: 1374260-17-9
tris(2,2,6,6-tetramethyl-8-{[2-(morpholin-4-yl)ethyl]carbonyl}-benzo[1,2-d;4,5-d']bis[1,3]dithiol-4-yl)methanol

Conditions

Conditions	Yield
Stage #1: tris(8-carboxyl-2,2,6,6-tetramethylbenzo[1,2-d;4,5-d']bis[1,3]dithiol-4-yl)methanol With 1,1'-carbonyldiimidazole In tetrahydrofuran at 55℃; for 4h; Inert atmosphere; Stage #2: 2-(morpholin-4-yl)ethanol In tetrahydrofuran at 20℃; for 1h; Inert atmosphere; Stage #3: With sodium hydride In tetrahydrofuran; mineral oil at 20℃; for 24h; Inert atmosphere;	96%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 2-chloro-N-(4-(5-(3,4-dichlorophenyl)-3-hydroxy-1H-1,2,4-triazol-1-yl)phenyl)acetamide

: 2-chloro-N-(4-(5-(3,4-dichlorophenyl)-3-(2-morpholinoethoxy)-1H-1,2,4-triazol-1-yl)phenyl)acetamide

Conditions

Conditions	Yield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 0 - 20℃; for 3h;	96%

: 622-40-2
2-(morpholin-4-yl)ethanol

: (3'aRS,6'aSR)-1-(cis-4-isopropylcyclohexyl)-2'-phenylhexahydrospiro[piperidine-4,1'-pyrrolo[3,4-c]pyrrole]-4',6'-dione

: (3'aRS,6'aSR)-1-(cis-4-isopropylcyclohexyl)-5'-(2-morpholin-4-yl-ethyl)-2'-phenylhexahydrospiro[piperidine-4,1'-pyrrolo[3,4-c]pyrrole]-4',6'-dione

Conditions

Conditions	Yield
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 20℃; for 24h; Mitsunobu reaction;	95%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 6702-50-7
3-hydroxy-4-methoxybenzoate

A: 250726-35-3
4-Methoxy-3-(2-morpholin-4-yl-ethoxy)benzoic acid methyl ester

B: 4114-28-7
diethyl hydrazodicarboxylate

Conditions

Conditions	Yield
With triphenylphosphine; diethylazodicarboxylate In ethyl acetate	A 95% B n/a

...Expand

: 622-40-2
2-(morpholin-4-yl)ethanol

: benzyl (2S,4aS,6aS,6bR,8aS,10S,12aS,12bR,14bR)-10-(chlorocarbonyl)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylate

: 2-benzyl 10-(2-morpholinoethyl)(2S,4aS,6aS,6bR,8aS,10S,12aS,12bR,14bR)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2,10-dicarboxylate

Conditions

Conditions	Yield
With dmap; triethylamine In dichloromethane at 20℃;	95%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 80-48-8
methyl p-toluene sulfonate

: 1206209-06-4
S4-(2-hydroxyethyl)-4-methylmorpholin-4-ium 4-methylbenzenesulfonate

Conditions

Conditions	Yield
In acetonitrile for 4h; Reflux;	94.4%
In acetonitrile for 4h; Reflux;	87%
In acetonitrile for 4h; Reflux;	84%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 68325-15-5
3-chloro-isonicotinonitrile

: 3-[2-(morpholin-4-yl)ethoxy]pyridine-4-carbonitrile

Conditions

Conditions	Yield
Stage #1: 2-(morpholin-4-yl)ethanol With sodium hydride In tetrahydrofuran; mineral oil at 20℃; for 1h; Stage #2: 3-chloro-isonicotinonitrile In tetrahydrofuran; mineral oil at 20℃; for 18h;	94%
Stage #1: 2-(morpholin-4-yl)ethanol With sodium hydride In tetrahydrofuran; mineral oil at 20℃; for 1h; Stage #2: 3-chloro-isonicotinonitrile In tetrahydrofuran; mineral oil at 20℃; for 18h;	94%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 867187-58-4
1-oxo-6-hydroxy-3-phenyl-1H-indene-2-carboxylic acid ethyl ester

: 867187-62-0
6-(2-morpholine-4-ylethoxy)-1-oxo-3-phenyl-1H-indene-2-carboxylic acid ethyl ester

Conditions

Conditions	Yield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran; benzene at 0 - 20℃; for 2h;	93%
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran; benzene at 0 - 20℃; for 2h;	93%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 4-fluoro-1-nitro-2-(prop-2-yn-1-yloxy)benzene

: 1202634-09-0
4-(4-nitro-3-(prop-2-ynyloxy)phenoxyethyl)morpholine

Conditions

Conditions	Yield
Stage #1: 2-(morpholin-4-yl)ethanol With sodium hydride In N,N-dimethyl-formamide at 20℃; Stage #2: 4-fluoro-1-nitro-2-(prop-2-yn-1-yloxy)benzene In N,N-dimethyl-formamide at -35℃; for 6h; Inert atmosphere;	93%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 540-38-5
4-Iodophenol

: 103808-71-5
4-<2-(p-iodophenoxy)ethyl>morpholine

Conditions

Conditions	Yield
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran; toluene at 20℃; for 17h; Cooling with ice;	93%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 610-81-1
4-hydroxy-2-nitroaniline

: 4-(2-morpholin-4-yl-ethoxy)-2-nitro-phenylamine

Conditions

Conditions	Yield
With triphenylphosphine; diethylazodicarboxylate In ethyl acetate	92%
With diisopropyl (E)-azodicarboxylate; triphenylphosphine In tetrahydrofuran
With diisopropyl (E)-azodicarboxylate; triphenylphosphine In tetrahydrofuran

2-Morpholinoethanol Chemical Properties

IUPAC Name: 2-Morpholin-4-ylethanol
Molecular Formula: C₆H₁₃NO₂
Molecular Weight: 131.17 g/mol
Molecular structure of 4-Morpholineethanol (CAS NO.622-40-2):

EINECS: 210-734-5
Melting Point: -1 °C
Boiling Point: 227 °C at 757 mm Hg(lit.)
Density: 1.083 g/mL at 25 °C(lit.)
Refractive Index: n20/D 1.476(lit.)
Flash Point: 211 °F
Water Solubility: miscible
Molar Refractivity: 34.48 cm³
Molar Volume: 123.6 cm³
XLogP3-AA: -0.8
H-Bond Donor: 1
H-Bond Acceptor: 3
Rotatable Bond Count: 2
Exact Mass: 131.094629
MonoIsotopic Mass: 131.094629
Topological Polar Surface Area: 32.7
Heavy Atom Count: 9
Canonical SMILES: C1COCCN1CCO
InChI: InChI=1S/C6H13NO2/c8-4-1-7-2-5-9-6-3-7/h8H,1-6H2
InChIKey: KKFDCBRMNNSAAW-UHFFFAOYSA-N
Classification Code: Mutation data; Skin / Eye Irritant

2-Morpholinoethanol Uses

4-Morpholineethanol (CAS NO.622-40-2) is commonly used in organic synthesis. It is also a kind of very important chemical pharmaceutical intermediates.

2-Morpholinoethanol Toxicity Data With Reference

1.	skn-rbt 10 mg/24H open	JIHTAB Journal of Industrial Hygiene and Toxicology. 30 (1948),63.
2.	eye-rbt 20 mg SEV	AJOPAA American Journal of Ophthalmology. 29 (1946),1363.
3.	dns-rat:lvr 5 g/L	MUREAV Mutation Research. 136 (1984),153.
4.	orl-rat LD₅₀:5500 mg/kg	JACTDZ Journal of the American College of Toxicology. 1 (1990),16.
5.	ipr-mus LD₅₀:3600 mg/kg	CANCAR Cancer. 2 (1949),1055.
6.	scu-mus LD₅₀:2650 mg/kg	AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 109 (1957),108.
7.	par-mus LDLo:4800 mg/kg	CBCCT* “Summary Tables of Biological Tests” National Research Council Chemical-Biological Coordination Center. 7 (1955),691.
8.	skn-gpg LD₅₀:2500 mg/kg	JIHTAB Journal of Industrial Hygiene and Toxicology. 30 (1948),63.

2-Morpholinoethanol Consensus Reports

Reported in EPA TSCA Inventory.

2-Morpholinoethanol Safety Profile

Hazard Codes: Irritant Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36-37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S37/39:Wear suitable gloves and eye/face protection.
WGK Germany: 1
RTECS: QE3510000
F: 10-23
HS Code: 29349990
Moderately toxic by skin contact, subcutaneous, and intraperitoneal routes. Mildly toxic by ingestion and parenteral routes. Mutation data reported. A skin and severe eye irritant. Combustible when exposed to heat or flame; can react with oxidizing materials. To fight fire, use alcohol foam, CO₂, dry chemical. When heated to decomposition it emits toxic fumes of NO_x.

2-Morpholinoethanol Specification

4-Morpholineethanol (CAS NO.622-40-2) is also named as 2-(4-Morpholinyl)ethanol ; 2-Morpholinoethanol ; 4-(2-Hydroxyethyl)morpholine ; 4-27-00-00056 (Beilstein Handbook Reference) ; AI3-03872 ; BRN 0104375 ; Ethanol, 2-(morpholinyl)- ; Ethanol, 2-morpholino- ; Hydroxyethylmorpholine ; Morpholine ethanol ; Morpholineethanol ; N-(2-Hydroxyethyl)morfolin ; N-(2-Hydroxyethyl)morfolin [Czech] ; N-(2-Hydroxyethyl)morpholine ; N-beta-Hydroxyethylmorpholine ; NSC 1946 ; beta-Morpholinoethanol ; beta-Oxyaethyl-morpholin ; beta-Oxyaethyl-morpholin [German] ; beta-Oxyaethyl-morpholin [German] . 4-Morpholineethanol (CAS NO.622-40-2) is clear colourless to yellow liquid.

Product Name

2-Morpholinoethanol

Synthetic route

2-Morpholinoethanol Chemical Properties

2-Morpholinoethanol Uses

2-Morpholinoethanol Toxicity Data With Reference

2-Morpholinoethanol Consensus Reports

2-Morpholinoethanol Safety Profile

2-Morpholinoethanol Specification

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