2-Tetrahydrofurfurylamine supplier

Name
2-Tetrahydrofurfurylamine
EINECS 225-351-9
CAS No. 4795-29-3
Article Data43
CAS DataBase
Density 0.967 g/cm³
Solubility miscible with water
Melting Point 156 °C at 760 mmHg
Formula C₅H₁₁NO
Boiling Point 45.6 °C
Molecular Weight 101.148
Flash Point 114 °F
Transport Information UN 2943 3/PG 3
Appearance Colorless to light yellow liquid
Safety 26-36-37/39-16
Risk Codes 10-36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Furfurylamine,tetrahydro- (6CI,7CI,8CI);(2-Tetrahydrofurylmethyl)amine;(RS)-(2-Tetrahydrofuryl)methylamine;(RS)-2-Tetrahydrofurfurylamine;(Tetrahydrofuran-2-yl)methanamine;(Tetrahydrofuran-2-ylmethyl)amine;1-(Tetrahydrofuran-2-yl)methanamine;2-(Aminomethyl)tetrahydrofuran;2-Tetrahydrofuranmethanamine;2-Tetrahydrofurfurylamine;C-(Tetrahydrofuran-2-yl)methylamine;N-[(Oxolan-2-yl)methyl]amine;NSC 76037;Tetrahydrofurfurylamine;2-aminomethyltetrahydrofuran;
PSA 35.25000
LogP 0.82440

Synthetic route

: 98-00-0
(2-furyl)methyl alcohol

: 4795-29-3
TETRAHYDROFURFURYLAMINE

Conditions

Conditions	Yield
With ammonia; hydrogen In tetrahydrofuran at 180℃; for 48h; Autoclave;	94%
With ammonia; hydrogen In tetrahydrofuran at 180℃; for 48h; Autoclave;	94 %Chromat.
Stage #1: (2-furyl)methyl alcohol With ammonia; nickel In tetrahydrofuran at 20℃; under 2625.26 Torr; for 0.333333h; Autoclave; Stage #2: With hydrogen In tetrahydrofuran at 180℃; under 7500.75 Torr; for 48h; Temperature; Pressure; Reagent/catalyst;

: 98-01-1
furfural

A: 97-99-4
Tetrahydrofurfuryl alcohol

B: 4795-29-3
TETRAHYDROFURFURYLAMINE

Conditions

Conditions	Yield
With ammonia; hydrogen In tetrahydrofuran at 180℃; for 12h; Autoclave;	A 5.1% B 91%
Multi-step reaction with 2 steps 1: ammonia; hydrogen / tetrahydrofuran / 2 h / 80 °C / Autoclave 2: ammonia; hydrogen / tetrahydrofuran / 24 h / 160 °C / Autoclave View Scheme

: 98-01-1
furfural

A: 4795-29-3
TETRAHYDROFURFURYLAMINE

B: 617-89-0
furan-2-ylmethanamine

Conditions

Conditions	Yield
With ammonia; hydrogen In tetrahydrofuran at 180℃; for 12h; Autoclave;	A 40.7% B 53.8%
With ammonia; hydrogen In methanol at 100℃; under 22502.3 Torr; for 0.25h; Autoclave; Green chemistry;	A 34% B 49%
With ethanol; ammonia; nickel at 180℃; under 73550.8 Torr; Hydrogenation;

: 88-14-2
2-furanoic acid

A: 109-99-9
tetrahydrofuran

B: 110-89-4
piperidine

C: 4795-29-3
TETRAHYDROFURFURYLAMINE

D: 110-58-7
1-pentanamine

E: 109-73-9
N-butylamine

Conditions

Conditions	Yield
Stage #1: 2-furanoic acid With cyclopentyl methyl ether; ammonia at 200℃; under 4500.45 Torr; Sealed tube; Green chemistry; Stage #2: With cyclopentyl methyl ether; ammonia; hydrogen at 200℃; under 42004.2 Torr; for 6.5h; Cooling with ice; Green chemistry;	A 13% B 9% C 43% D 6% E 10%

...Expand

: 98-01-1
furfural

A: 4795-29-3
TETRAHYDROFURFURYLAMINE

B: 19377-82-3
N-furfurylidenefurfurylamine

C: 617-89-0
furan-2-ylmethanamine

Conditions

Conditions	Yield
With 0.5% Ru/activated carbon; ammonia; hydrogen In methanol at 100℃; under 22502.3 Torr; for 0.25h; Autoclave; Green chemistry;	A 6% B 8% C 40%

...Expand

: 617-89-0
furan-2-ylmethanamine

: 4795-29-3
TETRAHYDROFURFURYLAMINE

Conditions

Conditions	Yield
With ammonia; hydrogen at 89.84℃; for 4h; High pressure;	36%
Hydrogenation;
With platinum(IV) oxide Hydrogenation;
With palladium on activated charcoal; acetic acid Hydrogenation;
With nickel at 115 - 140℃; under 58840.6 Torr; Hydrogenation;

: 98-00-0
(2-furyl)methyl alcohol

A: 97-99-4
Tetrahydrofurfuryl alcohol

B: 4795-29-3
TETRAHYDROFURFURYLAMINE

Conditions

Conditions	Yield
With ammonia; hydrogen In tetrahydrofuran at 160℃; for 24h; Autoclave;	A 12.6% B 34.2%
With ammonia; hydrogen In tetrahydrofuran at 160℃; for 24h; Autoclave;	A 15.5% B 11%
With ammonia; hydrogen In tetrahydrofuran at 160℃; for 24h; Autoclave;	A 15.5 %Chromat. B 11 %Chromat.

: 3003-84-7
Tetrahydrofurfuryl chloride

: 4795-29-3
TETRAHYDROFURFURYLAMINE

Conditions

Conditions	Yield
With ammonia; water at 150℃; im versilberten Gefaess;

: 97-99-4
Tetrahydrofurfuryl alcohol

: 4795-29-3
TETRAHYDROFURFURYLAMINE

Conditions

Conditions	Yield
With ammonia; nickel at 200℃; unter Druck;
With nickel-aluminium barium hydroxide-catalyst; ammonia; hydrogen at 210℃; under 12503.6 Torr;

: 494-47-3
hydrofuramide

A: 4795-29-3
TETRAHYDROFURFURYLAMINE

B: 18240-50-1
bis((furan-2-yl)methyl)amine

Conditions

Conditions	Yield
With kieselguhr; ethanol; nickel at 100℃; under 51485.6 - 80905.8 Torr; Hydrogenation;

: 494-47-3
hydrofuramide

A: 4795-29-3
TETRAHYDROFURFURYLAMINE

B: 5343-16-8
di-(2-tetrahydrofurfurylmethyl)amine

Conditions

Conditions	Yield
With diethyl ether; ethanol; nickel at 125℃; under 73550.8 - 110326 Torr; Hydrogenation;
With nickel; methyl cyclohexane at 125℃; under 73550.8 - 110326 Torr; Hydrogenation;
With diethyl ether; nickel at 125℃; under 73550.8 - 110326 Torr; Hydrogenation;
With ethanol; nickel at 125℃; under 73550.8 - 110326 Torr; Hydrogenation;

: 97-99-4
Tetrahydrofurfuryl alcohol

A: 110-89-4
piperidine

B: 4795-29-3
TETRAHYDROFURFURYLAMINE

C: 10324-58-0
1-pentylpiperidine

D: 1199-81-1
1-(tetrahydrofuran-2-ylmethyl)piperidine

E: 5343-16-8
di-(2-tetrahydrofurfurylmethyl)amine

Conditions

Conditions	Yield
With ammonia; hydrogen; CuO/ZnO/Al2O3 at 230℃; under 26252.1 Torr; Product distribution; other heterogenous Cu-, Ni-, Co- and Fe-containing bifunctional catalyst systems;	A 4.0 % Chromat. B 37 % Chromat. C 2.0 % Chromat. D 2.0 % Chromat. E 20.0 % Chromat.

...Expand

(+-)-benzyl-tetrahydrofurfuryl-amine: (+-)-benzyl-tetrahydrofurfuryl-amine

: 4795-29-3
TETRAHYDROFURFURYLAMINE

Conditions

Conditions	Yield
With Pd-BaSO4; ethanol Hydrogenation;

: 64-17-5
ethanol

: 494-47-3
hydrofuramide

nickel: nickel

A: 4795-29-3
TETRAHYDROFURFURYLAMINE

B: 18240-50-1
bis((furan-2-yl)methyl)amine

Conditions

Conditions	Yield
at 100℃; under 73550.8 Torr; Hydrogenation;

...Expand

: 23247-31-6
(E)-tetrahydrofuran-2-carbaldehyde oxime

: 64-17-5
ethanol

sodium: sodium

A: 4795-29-3
TETRAHYDROFURFURYLAMINE

B: 2508-29-4
5-hydroxypentylamine

...Expand

tetrahydro-furfurol oxime: tetrahydro-furfurol oxime

A: 4795-29-3
TETRAHYDROFURFURYLAMINE

B: 2508-29-4
5-hydroxypentylamine

Conditions

Conditions	Yield
With ethanol; sodium

(+-)-tetrahydrofuran-2-carboxamide: (+-)-tetrahydrofuran-2-carboxamide

A: 4795-29-3
TETRAHYDROFURFURYLAMINE

B: 5343-16-8
di-(2-tetrahydrofurfurylmethyl)amine

Conditions

Conditions	Yield
With 1,4-dioxane; copper oxide-chromium oxide at 250℃; under 147102 - 220652 Torr; Hydrogenation;
With 1,4-dioxane; copper oxide-chromium oxide at 250℃; under 147102 - 220652 Torr; Hydrogenation;

: 60-29-7
diethyl ether

: 494-47-3
hydrofuramide

nickel kieselguhr: nickel kieselguhr

A: 4795-29-3
TETRAHYDROFURFURYLAMINE

B: 5343-16-8
di-(2-tetrahydrofurfurylmethyl)amine

Conditions

Conditions	Yield
at 200℃; under 73550.8 - 110326 Torr; Hydrogenation;

...Expand

: 64-17-5
ethanol

: 494-47-3
hydrofuramide

nickel /kieselguhr: nickel /kieselguhr

A: 4795-29-3
TETRAHYDROFURFURYLAMINE

B: 5343-16-8
di-(2-tetrahydrofurfurylmethyl)amine

Conditions

Conditions	Yield
Hydrogenation;

...Expand

: 494-47-3
hydrofuramide

: 82166-21-0
methyl cyclohexane

nickel kieselguhr: nickel kieselguhr

A: 4795-29-3
TETRAHYDROFURFURYLAMINE

B: 5343-16-8
di-(2-tetrahydrofurfurylmethyl)amine

Conditions

Conditions	Yield
at 200℃; under 73550.8 - 110326 Torr; Hydrogenation;

...Expand

: 97-99-4
Tetrahydrofurfuryl alcohol

: 7664-41-7
ammonia

hydrogen: hydrogen

nickel-aluminium-alloy: nickel-aluminium-alloy

A: 4795-29-3
TETRAHYDROFURFURYLAMINE

B: tris-tetrahydrofurfuryl-amine

C: 5343-16-8
di-(2-tetrahydrofurfurylmethyl)amine

Conditions

Conditions	Yield
at 210℃; under 12503.6 Torr;

...Expand

: 97-99-4
Tetrahydrofurfuryl alcohol

: 7664-41-7
ammonia

nickel: nickel

A: 4795-29-3
TETRAHYDROFURFURYLAMINE

B: tris-tetrahydrofurfuryl-amine

C: 5343-16-8
di-(2-tetrahydrofurfurylmethyl)amine

Conditions

Conditions	Yield
at 160℃;

...Expand

: 1121-47-7
2-furaldehyde oxime

A: 4795-29-3
TETRAHYDROFURFURYLAMINE

B difurfurylamine and bis-tetrahydrofurfuryl-amine: difurfurylamine and bis-tetrahydrofurfuryl-amine

Conditions

Conditions	Yield
With ethanol; nickel at 150℃; Hydrogenation.unter Druck;

tetrahydrofurfurol oxime: tetrahydrofurfurol oxime

A: 4795-29-3
TETRAHYDROFURFURYLAMINE

B: 2508-29-4
5-hydroxypentylamine

Conditions

Conditions	Yield
With ethanol; sodium

(+-)-tetrahydro-furan-2-carboxamide: (+-)-tetrahydro-furan-2-carboxamide

A: 4795-29-3
TETRAHYDROFURFURYLAMINE

B: 5343-16-8
di-(2-tetrahydrofurfurylmethyl)amine

Conditions

Conditions	Yield
With 1,4-dioxane; copper oxide-chromium oxide at 250℃; under 147102 - 220652 Torr; Hydrogenation;
With 1,4-dioxane; copper oxide-chromium oxide at 250℃; under 147102 - 220652 Torr; Hydrogenation;

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 79-04-9
chloroacetyl chloride

: 39089-62-8
2-chloro-N-[(tetrahydrofuran-2-yl)methyl]acetamide

Conditions

Conditions	Yield
In dichloromethane	100%
With potassium carbonate In dichloromethane Heating;	97%
With trimethylamine In dichloromethane at 0 - 20℃; for 4h;	76%

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 4-bromo-2,5-difluorobenzenesulfonyl chloride

: 1034926-02-7
C11H12BrF2NO3S

Conditions

Conditions	Yield
In tetrahydrofuran at 20℃; for 24h;	100%

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 4-bromo-2-fluorobenzenesulfonyl chloride

: 1034926-01-6
C11H13BrFNO3S

Conditions

Conditions	Yield
In tetrahydrofuran at 20℃; for 24h;	100%

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 4-bromo-2-chlorobenzene-1-sulfonyl chloride

: 1034926-05-0
C11H13BrClNO3S

Conditions

Conditions	Yield
In tetrahydrofuran at 20℃; for 24h;	100%

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 1173799-71-7
1,1,1-trifluoro-N-((1S,2S)-2-isothiocyanatocyclohexyl)methanesulfonamide

: 1221716-46-6
1,1,1-trifluoro-N-((1S,2S)-2-(3-((tetrahydrofuran-2-yl)methyl)thioureido)cyclohexyl)methanesulfonamide

Conditions

Conditions	Yield
In chloroform-d1 at 20℃; for 2h; Inert atmosphere;	100%

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 68836-19-1
5-bromo-3-(methylthio)-1,4-diphenyl-1,2,4-triazolium bromide

: 76116-95-5
5-(tetrahydrofurfurylimino)-3-methylthio-1,4-diphenyl-Δ2-1,2,4-triazole

Conditions

Conditions	Yield
With triethylamine In chloroform at 0℃; for 0.166667h;	99%

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 607-68-1
2,4-dichloroquinazoline

: 2-chloro-N-((tetrahydrofuran-2-yl)methyl)quinazolin-4-amine

Conditions

Conditions	Yield
Stage #1: TETRAHYDROFURFURYLAMINE With triethylamine In methanol at 0℃; for 0.166667h; Inert atmosphere; Stage #2: 2,4-dichloroquinazoline In methanol; dichloromethane at 0 - 20℃; for 0.5h; Inert atmosphere;	99%
Stage #1: TETRAHYDROFURFURYLAMINE With triethylamine In methanol at 0℃; for 0.166667h; Inert atmosphere; Stage #2: 2,4-dichloroquinazoline In methanol; dichloromethane at 0 - 20℃; for 0.5h; Inert atmosphere;	99%
With sodium acetate In tetrahydrofuran; water at 65℃;	82%
With sodium hydroxide 1.) THF, 30 min, 2.) THF, 30 min; Multistep reaction;
With sodium acetate In tetrahydrofuran; water at 60℃;

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 4-bromo-3-fluorobenzene-1-sulfonyl chloride

: C11H13BrFNO3S

Conditions

Conditions	Yield
In tetrahydrofuran at 20℃; for 24h;	99%

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 6-chloro-2-[(4-methoxybenzyl)amino]nicotinic acid

: 6-chloro-2-[(4-methoxybenzyl)amino]-N-[(tetrahydrofuran-2-yl)methyl]nicotinamide

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane at 20℃; for 16h;	99%

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: C8H7ClFNO4S

: 4-chloro-5-(N-methylsulfamoyl)-2-(tetrahydrofuran-2-yl)methylaminobenzoic acid

Conditions

Conditions	Yield
With triethylamine In ethylene glycol at 130℃; for 16h;	99%

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 552-89-6
2-nitro-benzaldehyde

: [1-(2-Nitro-phenyl)-meth-(E)-ylidene]-(tetrahydro-furan-2-ylmethyl)-amine

Conditions

Conditions	Yield
With 4 A molecular sieve In diethyl ether at 20℃; for 2h; Condensation;	98%

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 999-97-3
1,1,1,3,3,3-hexamethyl-disilazane

: C4H7CH2NHSi(CH3)3O

Conditions

Conditions	Yield
With sulfuric acid at 160℃; for 0.5h;	98%

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 351003-54-8
4-bromo-2,6-dichlorobenzenesulfonyl chloride

: 1034926-06-1
C11H12BrCl2NO3S

Conditions

Conditions	Yield
In tetrahydrofuran at 20℃; for 24h;	98%

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 490-11-9
3,4-pyridinecarboxylic acid

: 950445-43-9
2-((tetrahydrofuran-2-yl)methyl)-2H-pyrrolo[3,4-c]pyridine-1,3-dione

Conditions

Conditions	Yield
for 0.0333333h; Microwave irradiation;	98%

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 98-61-3
4-iodobenzenesulfonyl chloride

: 326885-27-2
4-iodo-N-(tetrahydro-2-furanylmethyl)benzenesulfonamide

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 20℃; Cooling with ice/water; Inert atmosphere;	98%

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: S-(2-naphthylmethyl)thioacetimidate hydrobromide

: 1417785-60-4
N-(tetrahydrofuran-2-ylmethyl)acetamidine hydrobromide

Conditions

Conditions	Yield
In ethanol at 0 - 20℃;	98%

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 14631-43-7
2-tetrahydrofuran-2-carbonitrile

Conditions

Conditions	Yield
With pyridine; Oxone; 4-acetylamino-2,2,6,6-tetramethyl-1-piperidinoxy; Pyridine hydrobromide In dichloromethane at 20℃; for 12h; Green chemistry;	98%
With dmap; copper(l) iodide; 9-azabicyclo[3.3.1]nonane N-oxyl; oxygen; 4,4'-di-tert-butyl-2,2'-bipyridine In acetonitrile at 20℃; under 760.051 Torr; for 15h; Reagent/catalyst;	47 %Spectr.

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 93-58-3
benzoic acid methyl ester

: (±)-N-((tetrahydrofuran-2-yl)methyl)benzamide

Conditions

Conditions	Yield
With 14C2H2F3O(1-)6C4H8OLa2Na8(14+) at 80℃; for 6h; Inert atmosphere;	98%
With bis(1,5-cyclooctadiene)nickel (0); 1,3-bis(2,6-diisopropylphenyl)-1H-imidazol-3-ium In toluene at 140℃; for 16h; Glovebox; Inert atmosphere; Sealed tube;	88%
With C18H15IMnN3O3; sodium t-butanolate In toluene at 120℃; for 18h; Inert atmosphere; Schlenk technique;	76%
With zirconocene dichloride In toluene at 110℃; for 20h;	57%

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 7623-09-8
2-chloropropionyl chloride

: 596807-96-4
2-chloro-N-(tetrahydro-furan-2-ylmethyl)-propionamide

Conditions

Conditions	Yield
With potassium carbonate In dichloromethane Heating;	97%
With potassium carbonate In dichloromethane for 4h; Heating;

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 36082-50-5
2,4-dichloro-5-bromopyrimidine

: 5-bromo-2-chloro-N-((tetrahydrofuran-2-yl)methyl)pyrimidin-4-amine

Conditions

Conditions	Yield
With triethylamine In methanol at 0 - 20℃; Inert atmosphere;	97%

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 27631-29-4
2-chloro-6,7-dimethoxy-3H-quinazolin-4-one

: 2-chloro-6,7-dimethoxy-N-((tetrahydrofuran-2-yl)methyl)-quinazolin-4-amine

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In acetonitrile at 20℃; for 18h;	97%

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 50-00-0
formaldehyd

: 131543-46-9
Glyoxal

: 64-19-7
acetic acid

: 1,3-bis((tetrahydrofuran-2-yl)methyl)imidazolium acetate

Conditions

Conditions	Yield
Stage #1: TETRAHYDROFURFURYLAMINE; formaldehyd; acetic acid at 15℃; for 0.5h; Stage #2: Glyoxal at 20℃;	97%

...Expand

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 82140-87-2
3,3-Diazido-2-cyan-acrylsaeure-methylester

A: 130148-77-5
3-Azido-2-cyan-3-(tetrahydro-2-furylmethylamino)acrylsaeure-methylester

B: C5H11NO*HN3

Conditions

Conditions	Yield
In dichloromethane at -30℃; for 16h;	A 96% B n/a

...Expand

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 769956-97-0
(4-nitrophenyl) 3-O-benzyl-estradiol-16-carboxylate

: 769956-98-1
JAC01163-3

Conditions

Conditions	Yield
In acetonitrile at 20℃;	96%
In acetonitrile at 20℃;

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 55-21-0
benzamide

: (±)-N-((tetrahydrofuran-2-yl)methyl)benzamide

Conditions

Conditions	Yield
With benzoic acid In para-xylene at 130℃; for 8h; Inert atmosphere; Schlenk technique;	96%

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 20776-50-5
2-amino-4-bromobenzoic acid

: C12H15BrN2O2

Conditions

Conditions	Yield
Stage #1: 2-amino-4-bromobenzoic acid With N-ethyl-N,N-diisopropylamine; HATU In dichloromethane at 20℃; for 0.25h; Stage #2: TETRAHYDROFURFURYLAMINE In dichloromethane at 20℃; for 2h;	96%

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 454-89-7
3-Trifluoromethylbenzaldehyde

: 912291-16-8
1-(tetrahydrofuran-2-yl)-N-(3-(trifluoromethyl)benzyl)methanamine

Conditions

Conditions	Yield
Stage #1: TETRAHYDROFURFURYLAMINE; 3-Trifluoromethylbenzaldehyde In chloroform at 60℃; Stage #2: With sodium tetrahydroborate In methanol at 25℃;	96%

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 85-44-9
phthalic anhydride

: 26116-10-9
2-((tetrahydrofuran-2-yl)methyl)isoindoline-1,3-dione

Conditions

Conditions	Yield
In chloroform Heating;	95.2%
at 120℃; for 3h;	95%
In chloroform Reflux;	95.2%
With sodium hydrogencarbonate In chloroform; water

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: ethyl 2-(4-bromo-2-chloro-benzoyl)-3-dimethylamino-acrylate

: ethyl 2-(4-bromo-2-chloro-benzoyl)-3-[(tetrahydro-furan-2-ylmethyl)-amino]-acrylate

Conditions

Conditions	Yield
In tetrahydrofuran	95%

: 4795-29-3
TETRAHYDROFURFURYLAMINE

: 570-22-9
4,5-imidazoledicarboxylic acid

: 1204831-04-8
5-((tetrahydrofuran-2-yl)methyl)pyrrolo[3,4-d]imidazole-4,6(1H,5H)-dione

Conditions

Conditions	Yield
for 0.0666667h; Microwave irradiation;	95%

2-Tetrahydrofurfurylamine Consensus Reports

Reported in EPA TSCA Inventory.

2-Tetrahydrofurfurylamine Standards and Recommendations

DOT Classification: 3; Label: Flammable Liquid

2-Tetrahydrofurfurylamine Specification

The Tetrahydrofurfurylamine, also known as 2-Tetrahydrofurfurylamine, is an organic compound with the formula C₅H₁₁NO. It belongs to the product categories of Furan & Benzofuran; Amines. Its EINECS registry number is 225-351-9. With the CAS registry number 4795-29-3, its IUPAC name is oxolan-2-ylmethanamine.

Physical properties of Tetrahydrofurfurylamine: (1)ACD/LogP: -0.66; (2)#H bond acceptors: 2; (3)#H bond donors: 2; (4)#Freely Rotating Bonds: 2; (5)Index of Refraction: 1.453; (6)Molar Refractivity: 28.28 cm³; (7)Molar Volume: 104.5 cm³; (8)Surface Tension: 37.2 dyne/cm; (9)Density: 0.967 g/cm³; (10)Flash Point: 45.6 °C; (11)Enthalpy of Vaporization: 39.27 kJ/mol; (12)Boiling Point: 156 °C at 760 mmHg; (13)Vapour Pressure: 2.95 mmHg at 25°C.

Uses of Tetrahydrofurfurylamine: it can be used to produce N-tetrahydrofurfuryl-phthalimide with phthalic acid anhydride by heating. This reaction will need solvent CHCl₃. The yield is about 95.2%.

Tetrahydrofurfurylamine can be used to produce N-tetrahydrofurfuryl-phthalimide with phthalic acid anhydride by heating

When you are using this chemical, please be cautious about it as the following:
This chemical may cause inflammation to the skin or other mucous membranes. It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. Whenever you will contact it, please wear suitable protective clothing, gloves and eye/face protection.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C1CC(OC1)CN
(2)InChI: InChI=1S/C5H11NO/c6-4-5-2-1-3-7-5/h5H,1-4,6H2
(3)InChIKey: YNOGYQAEJGADFJ-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	200mg/kg (200mg/kg)		National Technical Information Service. Vol. AD277-689,

Product Name

2-Tetrahydrofurfurylamine

Synthetic route

2-Tetrahydrofurfurylamine Consensus Reports

2-Tetrahydrofurfurylamine Standards and Recommendations

2-Tetrahydrofurfurylamine Specification

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