4-Isopropylbenzeneboronic acid supplier

Name
4-Isopropylbenzeneboronic acid
EINECS
CAS No. 16152-51-5
Article Data9
CAS DataBase
Density 1.04 g/cm³
Solubility
Melting Point 110-112 °C
Formula C₉H₁₃BO₂
Boiling Point 285.9 °C at 760 mmHg
Molecular Weight 164.012
Flash Point 126.7 °C
Transport Information
Appearance
Safety 26-36/37/39
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms 4-Cumylboronic acid;4-Isopropylphenylboronic;4-iso-propylphenyl boronic acid;
PSA 40.46000
LogP 0.48980

Synthetic route

: 99-88-7
4-Isopropylaniline

: 73183-34-3
bis(pinacol)diborane

: 16152-51-5
(4-isopropylphenyl)boronic acid

Conditions

Conditions	Yield
With tert.-butylnitrite In acetonitrile at 0 - 80℃; for 2h;	99.8%
With tert.-butylnitrite In acetonitrile at 0 - 80℃; for 2h;	99.8%

: 586-61-8
2-(4-bromophenyl)propane

: 16152-51-5
(4-isopropylphenyl)boronic acid

Conditions

Conditions	Yield
	63%

: 121-43-7
Trimethyl borate

: 586-61-8
2-(4-bromophenyl)propane

: 153624-04-5
N-(3,4-Dimethyl-5-isoxazolyl)-4'-(2-methylpropyl)-[1,1'-biphenyl]-2-sulfonamide

: 16152-51-5
(4-isopropylphenyl)boronic acid

...Expand

: 121-43-7
Trimethyl borate

: 586-61-8
2-(4-bromophenyl)propane

: 16152-51-5
(4-isopropylphenyl)boronic acid

Conditions

Conditions	Yield
With n-butyllithium In tetrahydrofuran at -78 - 0℃;

: 16152-51-5
(4-isopropylphenyl)boronic acid

: 16657-07-1
4-bromo-3H-indene

: 4-(4-isopropylphenyl)indene

Conditions

Conditions	Yield
With bis-triphenylphosphine-palladium(II) chloride; potassium phosphate; triphenylphosphine In 1,2-dimethoxyethane; water at 90℃; for 8h;	100%

: 16152-51-5
(4-isopropylphenyl)boronic acid

: C25H27N3O3

: C32H33N3O

Conditions

Conditions	Yield
Stage #1: C25H27N3O3 With trichlorophosphate In toluene at 100℃; for 0.5h; Microwave irradiation; Stage #2: (4-isopropylphenyl)boronic acid With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate In 1,4-dioxane at 90℃; for 16h; Stage #3: With hydrogenchloride In tetrahydrofuran; water at 20℃;	100%

: 16152-51-5
(4-isopropylphenyl)boronic acid

: 45738-35-0
4-bromo-indene

: 4-(4-isopropylphenyl)indene

Conditions

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); caesium carbonate In 1,2-dimethoxyethane; water at 80℃; for 6h;	99%
Stage #1: (4-isopropylphenyl)boronic acid; 4-bromo-indene With bis-triphenylphosphine-palladium(II) chloride; potassium phosphate In 1,2-dimethoxyethane; water at 90℃; for 8h; Stage #2: With hydrogenchloride In hexane; water at 20℃; for 0.5h;	97%

: 1639431-68-7
3-chloro-4-(4-methoxyphenyl)-2,5,6-triphenylpyridine

: 16152-51-5
(4-isopropylphenyl)boronic acid

: 1639431-69-8
3-(4-isopropylphenyl)-4-(4-methoxyphenyl)-2,5,6-triphenylpyridine

Conditions

Conditions	Yield
With dichloro bis(acetonitrile) palladium(II); potassium phosphate; 2-dicyclohexylphosphino-2’,6’-dimethoxybiphenyl In toluene at 100℃; for 20h; Suzuki-Miyaura Coupling; Inert atmosphere; Schlenk technique; Sealed tube;	98%

: 16152-51-5
(4-isopropylphenyl)boronic acid

: C14H18N2O4S

: C23H30N2O4S

Conditions

Conditions	Yield
With acetylacetonatobis(ethylene)rhodium(I); C22H18NO2P In toluene at 25℃; for 20h; Inert atmosphere; enantioselective reaction;	98%

: 75-15-0
carbon disulfide

: 16152-51-5
(4-isopropylphenyl)boronic acid

: 109-89-7
diethylamine

: 4-isopropylphenyl diethylcarbamodithioate

Conditions

Conditions	Yield
With copper diacetate; potassium carbonate In acetonitrile at 60℃; for 10h; Schlenk technique;	98%

...Expand

: 16152-51-5
(4-isopropylphenyl)boronic acid

: 7-bromo-2,3-dihydrobenzofuran-5-amine

: 7-(4-isopropylphenyl)-2,3-dihydrobenzofuran-5-amine

Conditions

Conditions	Yield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate In 1,4-dioxane; water at 100℃; for 2h; Inert atmosphere;	98%

: 16152-51-5
(4-isopropylphenyl)boronic acid

: 7722-84-1
dihydrogen peroxide

: 99-89-8
4-Isopropylphenol

Conditions

Conditions	Yield
With ammonium bicarbonate In water at 20℃; for 2h; Schlenk technique;	97%

: 872-31-1
3-Bromothiophene

: 16152-51-5
(4-isopropylphenyl)boronic acid

: 3‐(4‐cumenyl)‐thiophene

Conditions

Conditions	Yield
Stage #1: 3-Bromothiophene With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In monoethylene glycol diethyl ether; water at 20℃; for 0.166667h; Schlenk technique; Inert atmosphere; Stage #2: (4-isopropylphenyl)boronic acid In ethanol; monoethylene glycol diethyl ether; water for 1h; Schlenk technique; Inert atmosphere; Reflux;	97%

: 108-86-1
bromobenzene

: 16152-51-5
(4-isopropylphenyl)boronic acid

: 7116-95-2
4-isopropylbiphenyl

Conditions

Conditions	Yield
With potassium phosphate tribasic trihydrate In ethanol; water at 30℃; for 7h; Catalytic behavior; Suzuki-Miyaura Coupling;	97%
With bis-triphenylphosphine-palladium(II) chloride; potassium carbonate In ethanol; water at 80℃; for 2h; Sealed tube;	76%

: 16152-51-5
(4-isopropylphenyl)boronic acid

: C13H7BrClNOS

: C22H18ClNOS

Conditions

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In ethanol; toluene at 80℃; for 24h;	96.8%

: 4595-59-9
5-bromopyrimidine

: 16152-51-5
(4-isopropylphenyl)boronic acid

: 5-(4-isopropyl-phenyl)-pyrimidine

Conditions

Conditions	Yield
With Merrifield resin chloride triethylamine salt; diisopropylamine; palladium diacetate In water; acetonitrile at 85℃; for 6.5h; Suzuki coupling;	96%

: 16152-51-5
(4-isopropylphenyl)boronic acid

: 99-89-8
4-Isopropylphenol

Conditions

Conditions	Yield
With dihydrogen peroxide In ethanol at 20℃; for 0.166667h;	96%
With iron(III) oxide; oxygen In tetrahydrofuran Irradiation;	95%
With iron(III) oxide; oxygen In tetrahydrofuran at 20℃; Irradiation;	95%

: 13484-50-9
tetrachloropyrazine

: 16152-51-5
(4-isopropylphenyl)boronic acid

: 2,3,5,6-tetrakis(4-isopropylphenyl)pyrazine

Conditions

Conditions	Yield
With potassium phosphate; palladium diacetate; tricyclohexylphosphine In toluene at 100℃; for 18h; Suzuki-Miyaura Coupling; Schlenk technique; Inert atmosphere;	96%

: 16152-51-5
(4-isopropylphenyl)boronic acid

: C18H17NO3S

: C27H29NO3S

Conditions

Conditions	Yield
With (CF3SO3)2 In 1,2-dimethoxyethane; water at 20℃; for 36h; diastereoselective reaction;	96%

: 16152-51-5
(4-isopropylphenyl)boronic acid

: 3-methyl-4-bromoindene

: 3-methyl-4-(4-i-propylphenyl)indene

Conditions

Conditions	Yield
With potassium phosphate; bis(dibenzylideneacetone)-palladium(0); XPhos In 1,2-dimethoxyethane; water for 16h; Reflux;	96%

: 3485-80-1
1-iodo-9,10-anthraquinone

: 16152-51-5
(4-isopropylphenyl)boronic acid

: 853993-35-8
1-(4-isopropylphenyl)-9,10-anthraquinone

Conditions

Conditions	Yield
With sodium carbonate; tetrakis(triphenylphosphine) palladium(0) In ethanol; water; toluene for 30h; Heating;	95%
Suzuki coupling;

: 151326-85-1
4'-[(5-oxo-7-propyl-4,5-dihydro[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)methyl]biphenyl-2-carbonitrile

: 16152-51-5
(4-isopropylphenyl)boronic acid

: 1239269-49-8
4'-({4-[4-(1-methylethyl)phenyl]-5-oxo-7-propyl-4,5-dihydro[1,2,4]triazolo[1,5-a]pyrimidin-6-yl}methyl)biphenyl-2-carbonitrile

Conditions

Conditions	Yield
With pyridine; copper diacetate; triethylamine In N,N-dimethyl-formamide for 16h; Micellar solution;	95%

: C10H6Br2S

: 16152-51-5
(4-isopropylphenyl)boronic acid

: C28H28S

Conditions

Conditions	Yield
Stage #1: C10H6Br2S; (4-isopropylphenyl)boronic acid With sodium carbonate In ethanol; water; toluene at 80℃; for 1.5h; Inert atmosphere; Stage #2: With tetrakis(triphenylphosphine) palladium(0) In ethanol; water; toluene at 72℃; Inert atmosphere;	95%

: 16152-51-5
(4-isopropylphenyl)boronic acid

: C21H13ClFN5O2

: N-{[3,6-bis(furan-2-yl)pyrazin-2-yl]methyl}-7-fluoro-4-p-isopropylphenylquinazolin-6-amine

Conditions

Conditions	Yield
Stage #1: C21H13ClFN5O2 With tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 60℃; for 1h; Inert atmosphere; Stage #2: (4-isopropylphenyl)boronic acid With sodium carbonate In N,N-dimethyl-formamide at 90℃; for 5h; Inert atmosphere;	95%

: 619-44-3
methyl 4-iodobenzoate

: 16152-51-5
(4-isopropylphenyl)boronic acid

: 10047-16-2
methyl 4'-isopropyl-[1,1'-biphenyl]-4-carboxylate

Conditions

Conditions	Yield
With potassium carbonate; bis[1,2-bis(diphenylphosphino)ethane]palladium In tetrahydrofuran; methanol; water at 20℃; for 2h;	94%

: 1202929-10-9
C11H8O3

: 16152-51-5
(4-isopropylphenyl)boronic acid

: C20H20O3

Conditions

Conditions	Yield
With [Pd(S,S)-bdpp(H2O)2](2+)(BF4(1-))2 In 1,4-dioxane at 20℃; for 1.33333h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	94%

: 16152-51-5
(4-isopropylphenyl)boronic acid

: 109-77-3
malononitrile

: 3-oxo-3-[4-(propan-2-yl)phenyl]propanenitrile

Conditions

Conditions	Yield
With 4,4'-dimethyl-2,2'-bipyridines; palladium(II) acetylacetonate; toluene-4-sulfonic acid In water; toluene at 80℃; for 24h; Schlenk technique;	94%

: 655-32-3
2,2,2-trifluoro-1-(4-fluorophenyl)ethanone

: 16152-51-5
(4-isopropylphenyl)boronic acid

: (R)-2,2,2-trifluoro-1-(4-fluorophenyl)-1-(4-isopropylphenyl)ethanol

Conditions

Conditions	Yield
With chlorobis(ethylene)rhodium(I) dimer; C38H44O6P2; potassium carbonate In tert-butyl methyl ether at 60℃; for 20h; Inert atmosphere; enantioselective reaction;	93%

: 1182669-71-1
N-(2-methylbenzoyl)-8-aminoquinoline

: 16152-51-5
(4-isopropylphenyl)boronic acid

: 4′-isopropyl-3-methyl-N-(quinolin-8-yl)-[1,1′-biphenyl]-2-carboxamide

Conditions

Conditions	Yield
With copper diacetate; sodium carbonate In dimethyl sulfoxide at 120℃; for 4h; Sealed tube; regioselective reaction;	93%
With sodium carbonate; silver carbonate; cobalt acetylacetonate In dimethyl sulfoxide at 120℃; for 2h; Schlenk technique; Sealed tube;	83%

: 496062-17-0
ethyl {(1S)-5-[2-(2-bromo-5-methyl-1,3-thiazol-4-yl)ethoxy]-2,3-dihydro-1H-inden-1-yl}acetate

: 16152-51-5
(4-isopropylphenyl)boronic acid

: 496063-11-7
ethyl ((1S)-5-{2-[2-(4-isopropylphenyl)-5-methyl-1,3-thiazol-4-yl]ethoxy}-2,3-dihydro-1H-inden-1-yl)acetate

Conditions

Conditions	Yield
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; sodium carbonate In 1,4-dioxane; toluene at 75℃; for 18h; Inert atmosphere;	93%

: 16152-51-5
(4-isopropylphenyl)boronic acid

: C19H22BrNO3S

: 496062-17-0
ethyl {(1S)-5-[2-(2-bromo-5-methyl-1,3-thiazol-4-yl)ethoxy]-2,3-dihydro-1H-inden-1-yl}acetate

Conditions

Conditions	Yield
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; sodium carbonate In 1,4-dioxane; toluene at 75℃; for 18h; Suzuki Coupling; Inert atmosphere;	93%

: 583-39-1
2,3-dihydrobenzimidazol-2-thione

: 16152-51-5
(4-isopropylphenyl)boronic acid

: 1-(4-isopropylphenyl)-1H-benzo[d]imidazole

Conditions

Conditions	Yield
With copper(II) acetate monohydrate; sodium hydrogencarbonate In dimethyl sulfoxide at 100℃; Chan-Lam Coupling; chemoselective reaction;	93%

: 16152-51-5
(4-isopropylphenyl)boronic acid

: 479-27-6
naphthalene-1,8-diamine

: 2-(4-isopropylphenyl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2] diazaborinine

Conditions

Conditions	Yield
In water at 60℃; for 2h; Green chemistry;	93%

4-Isopropylbenzeneboronic acid Chemical Properties

IUPAC Name: (4-Propan-2-ylphenyl)boronic acid
Molecular Formula: C₉H₁₃BO₂
Molecular Weight: 164.01 g/mol
SMILES: OB(O)c1ccc(cc1)C(C)C
InChI: InChI=1/C9H13BO2/c1-7(2)8-3-5-9(6-4-8)10(11)12/h3-7,11-12H,1-2H3
Product Categories: blocks; BoronicAcids; Boronic Acid series; Substituted Boronic Acids; Boronic acids; Boronic Acid;Aryl; Organoborons; B (Classes of Boron Compounds)
Index of Refraction: 1.513
Molar Refractivity: 47.14 cm³
Molar Volume: 156.7 cm³
Polarizability: 18.69×10^-24 cm³
Surface Tension: 37.5 dyne/cm
Density: 1.04 g/cm³
Flash Point: 126.7 °C
Enthalpy of Vaporization: 55.45 kJ/mol
Boiling Point: 285.9 °C at 760 mmHg
Melting Point: 110-112 °C
Vapour Pressure of 4-Isopropylbenzeneboronic acid (CAS NO.16152-51-5): 0.00127 mmHg at 25 °C

4-Isopropylbenzeneboronic acid Safety Profile

Hazard Codes: Irritant Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
Hazard Note: Irritant
HazardClass of 4-Isopropylbenzeneboronic acid (CAS NO.16152-51-5): IRRITANT

4-Isopropylbenzeneboronic acid Specification

4-Isopropylbenzeneboronic acid (CAS NO.16152-51-5), its Synonyms are p-Isopropylphenylboronic acid ; 4-Cumylboronic acid ; 4-isopropylphenylboronic acid .

Product Name

4-Isopropylbenzeneboronic acid

Synthetic route

4-Isopropylbenzeneboronic acid Chemical Properties

4-Isopropylbenzeneboronic acid Safety Profile

4-Isopropylbenzeneboronic acid Specification

Related Products

Hot Products