Acetosyringone supplier | CasNO.2478-38-8

Name
Acetosyringone
EINECS 219-610-5
CAS No. 2478-38-8
Article Data37
CAS DataBase
Density 1.172 g/cm³
Solubility soluble in water
Melting Point 124-127 °C(lit.)
Formula C₁₀H₁₂O₄
Boiling Point 334.7 °C at 760 mmHg
Molecular Weight 196.203
Flash Point 131.7 °C
Transport Information
Appearance beige to light brown crystalline powder
Safety 26-36
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Acetophenone,4'-hydroxy-3',5'-dimethoxy- (6CI,7CI,8CI);1-(4-Hydroxy-3,5-dimethoxyphenyl)ethanone;2,6-Dimethoxy-4-acetophenol;2,6-Dimethoxy-4-acetylphenol;3',5'-Dimethoxy-4'-hydroxyacetophenone;4-Acetyl-2,6-dimethoxyphenol;4'-Hydroxy-3',5'-dimethoxyacetophenone;Syringone;Syringylethanone;Acetosyringone;
PSA 55.76000
LogP 1.61200

Synthetic route

: 1136-86-3
methyl (3,4,5-trimethoxyphenyl) ketone

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
With lithium thioethoxide In N,N-dimethyl-formamide at 70℃; for 0.25h; Inert atmosphere; Microwave irradiation; regioselective reaction;	95%
With magnesium iodide for 0.5h; neat (no solvent);	90%
With zirconium(IV) chloride; methoxybenzene In dichloromethane at 40℃; for 48h; Sealed tube;	63%

: 383176-01-0
methyl 4-O-tert-butyldimethylsilyl-3,5-dimethoxybenzoate

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
With tetrabutyl ammonium fluoride	92%

: 33900-62-8
1-(4-Hydroxy-3,5-dimethoxyphenyl)ethanol

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
With copper diacetate; ethylene glycol at 50℃; for 8h; Green chemistry; chemoselective reaction;	91%

: 14059-92-8
4-ethylsyringol

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
With copper diacetate; ethylene glycol at 90℃; for 12h; Green chemistry; chemoselective reaction;	84%

: 1105671-50-8
C11H16O4

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
With copper diacetate; ethylene glycol at 50℃; for 8h; Green chemistry; chemoselective reaction;	83%

: 33900-62-8
1-(4-Hydroxy-3,5-dimethoxyphenyl)ethanol

A: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

B: 530-55-2
2,6-dimethoxy-p-quinone

Conditions

Conditions	Yield
With oxygen; (pyridine)cobalt In methanol under 2585.7 Torr; for 24h; Ambient temperature; Title compound not separated from byproducts;	A 4 % Spectr. B 82%
With oxygen; (pyridine)cobalt In methanol under 2585.7 Torr; for 24h; Ambient temperature;	A 4 % Spectr. B 82%

: 944-99-0
acetic acid 2,6-dimethoxy-phenyl ester

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
With bismuth(lll) trifluoromethanesulfonate In toluene for 1h; Fries rearrangement; Heating;	80%
With aluminum (III) chloride In nitrobenzene at 0℃; Solvent; Reagent/catalyst;	80%
With aluminium trichloride; nitrobenzene at 2 - 3℃; dann bei Zimmertemperatur;
With aluminium trichloride; nitrobenzene
With aluminium trichloride In nitrobenzene

: 871798-98-0
3,3'-dimethoxy-4-carboxymethoxyacetophenone

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
Stage #1: 3,3'-dimethoxy-4-carboxymethoxyacetophenone With triethylamine In N,N-dimethyl-formamide; toluene for 3h; Curtius rearrangement; Heating; Stage #2: With potassium hydroxide; glycerol In ethanol; N,N-dimethyl-formamide; toluene for 2h; Heating; Further stages.;	70%

: 103440-59-1
1-(4-hydroxy-3-iodo-5-methoxy-phenyl)ethan-1-one

: 124-41-4
sodium methylate

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
With methanol; copper at 140℃;

: 76246-81-6
1-(4-hydroxy-3,5-dimethoxyphenyl)ethanone benzyl ether

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
With hydrogen bromide; acetic acid bei gewoehnlicher Temperatur;

: 91-10-1
1,3-dimethoxy-2-hydroxy-benzene

: 64-19-7
acetic acid

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
With boron trifluoride

: 123-75-1
pyrrolidine

: 28294-47-5
1-(4-acetoxy-3,5-dimethoxy-phenyl)-ethanone

A: 4030-18-6
N-(acetyl)pyrrolidine

B: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
for 0.05h; Ambient temperature;

...Expand

: 91-10-1
1,3-dimethoxy-2-hydroxy-benzene

: 75-36-5
acetyl chloride

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
(i), (ii) AlCl3, PhNO2; Multistep reaction;

: 284043-12-5
4-amino-butyric acid 2-(4-hydroxy-3,5-dimethoxy-phenyl)-2-oxo-ethyl ester

A: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

B: 90426-22-5
3',5'-dimethoxy-4'-hydroxy-(2-hydroxy)acetophenone

C: 56-12-2
4-amino-n-butyric acid

Conditions

Conditions	Yield
With water Hydrolysis; reduction; UV-irradiation;

...Expand

forest plant material: forest plant material

A: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

B: 4206-58-0
(E)-sinapinaldehyde

C: 19037-58-2
1-(3,5-dimethoxy-4-hydroxyphenyl)propan-2-one

D: 2-(4-hydroxy-3,5-dimethoxyphenyl)acetaldehyde

Conditions

Conditions	Yield
With air Oxidation; Formation of xenobiotics; Further byproducts given;

...Expand

: 39151-19-4
1-(3,5-dimethoxyphenyl)ethan-1-one

A: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

B: 17605-00-4
2ʹ-hydroxy-3ʹ,5ʹ-dimethoxyacetophenone

Conditions

Conditions	Yield
With toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid In acetonitrile at 80℃; for 2h;	A 3 % Chromat. B 11 % Chromat.

: γ-O-(3,5-dimethoxy-4-hydroxyphenacyl) L-glutamate, trifluoroacetate salt

A: 56-86-0
L-glutamic acid

B: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

C: 90426-22-5
3',5'-dimethoxy-4'-hydroxy-(2-hydroxy)acetophenone

Conditions

Conditions	Yield
With water Hydrolysis; reduction; UV-irradiation;

...Expand

: 51149-28-1
2-bromo-1-(4-hydroxy-3,5-dimethoxyphenyl)ethanone

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: DBU / dioxane / 12 h / 0 - 20 °C 2: TFA / 4 h / 0 °C 3: H2O / UV-irradiation View Scheme
Multi-step reaction with 3 steps 1: 67 percent / DBU / benzene / 12 h / 20 °C 2: 98 percent / TFA / 4 h / 0 °C 3: H2O / UV-irradiation View Scheme

: 284043-14-7
4-tert-butoxycarbonylamino-butyric acid 2-(4-hydroxy-3,5-dimethoxy-phenyl)-2-oxo-ethyl ester

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: TFA / 4 h / 0 °C 2: H2O / UV-irradiation View Scheme

: 284043-08-9
γ-O-(3,5-dimethoxy-4-hydroxyphenacyl) t-butyl N-t-boc L-glutamate

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 98 percent / TFA / 4 h / 0 °C 2: H2O / UV-irradiation View Scheme

: 498-02-2
1-(3-methoxy-4-hydroxyphenyl)ethanone

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: aqueous KI; NaHCO3; iodine 2: copper; methanol / 140 °C View Scheme

: 91-10-1
1,3-dimethoxy-2-hydroxy-benzene

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: pyridine; benzene / anschliessendes Erwaermen auf 60grad 2: AlCl3; nitrobenzene View Scheme

: 530-57-4
3,5-dimethoxy-4-hydroxybenzoic acid

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
Multi-step reaction with 6 steps 1: NaOH-solution 2: benzene; phosphorus pentachloride / 0 °C 3: alcohol; diethyl ether 4: ammonium chloride; diluted ammonia 5: water / 175 - 180 °C 6: hydrogen bromide; glacial acetic acid / bei gewoehnlicher Temperatur View Scheme

: 27065-65-2
methyl 4-benzyloxy-3,5-dimethoxybenzoate

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
Multi-step reaction with 6 steps 1: NaOH-solution / durch Verseifung 2: benzene; phosphorus pentachloride / 0 °C 3: alcohol; diethyl ether 4: ammonium chloride; diluted ammonia 5: water / 175 - 180 °C 6: hydrogen bromide; glacial acetic acid / bei gewoehnlicher Temperatur View Scheme

: 884-35-5
methyl syringate

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
Multi-step reaction with 7 steps 1: methanolic KOH-solution 2: NaOH-solution / durch Verseifung 3: benzene; phosphorus pentachloride / 0 °C 4: alcohol; diethyl ether 5: ammonium chloride; diluted ammonia 6: water / 175 - 180 °C 7: hydrogen bromide; glacial acetic acid / bei gewoehnlicher Temperatur View Scheme

: 30835-78-0
ethyl 3-(4-benzyloxy-3,5-dimethoxyphenyl)-3-oxopropionate

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: water / 175 - 180 °C 2: hydrogen bromide; glacial acetic acid / bei gewoehnlicher Temperatur View Scheme

: 14588-61-5
4-benzyloxy-3,5-dimethoxybenzoic acid chloride

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: alcohol; diethyl ether 2: ammonium chloride; diluted ammonia 3: water / 175 - 180 °C 4: hydrogen bromide; glacial acetic acid / bei gewoehnlicher Temperatur View Scheme

: 860579-04-0
2-(4-benzyloxy-3,5-dimethoxy-benzoyl)-3-oxo-butyric acid ethyl ester

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: ammonium chloride; diluted ammonia 2: water / 175 - 180 °C 3: hydrogen bromide; glacial acetic acid / bei gewoehnlicher Temperatur View Scheme

: 14588-60-4
4-(benzyloxy)-3,5-dimethoxybenzoic acid

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1: benzene; phosphorus pentachloride / 0 °C 2: alcohol; diethyl ether 3: ammonium chloride; diluted ammonia 4: water / 175 - 180 °C 5: hydrogen bromide; glacial acetic acid / bei gewoehnlicher Temperatur View Scheme

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

: 75-36-5
acetyl chloride

: 28294-47-5
1-(4-acetoxy-3,5-dimethoxy-phenyl)-ethanone

Conditions

Conditions	Yield
With potassium carbonate; triethylamine In dichloromethane	99%

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

: 32247-96-4
3,5-bis(trifluoromethyl)benzyl bromide

: 1-[4-(3,5-Bis-trifluoromethyl-benzyloxy)-3,5-dimethoxy-phenyl]-ethanone

Conditions

Conditions	Yield
With sodium hydroxide In water; acetonitrile for 5h; Heating;	95%

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

: 3′,5′-dimethoxy-4′-hydroxyacetophenone oxime

Conditions

Conditions	Yield
With hydroxylamine hydrochloride; sodium acetate In methanol; water at 60℃;	93%
With hydroxylamine hydrochloride; sodium acetate In water at 80℃; for 2h;	47%

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

: 105-36-2
ethyl bromoacetate

: 383176-05-4
ethyl (4-acetyl-2,6-dimethoxyphenoxy)acetate

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide for 18h;	90%

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

: 102229-10-7
2-(tert-butyldimethylsilyloxy)ethanol

: 1-{4-[2-(tert-butyl-dimethyl-silanyloxy)-ethoxy]-3,5-dimethoxy-phenyl}-ethanone

Conditions

Conditions	Yield
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 0 - 20℃; Mitsunobu reaction;	87%

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

: 1-(4-hydroxy-3,5-dimethoxyphenyl)-2-iodoethanone

Conditions

Conditions	Yield
With iodine; Selectfluor In methanol at 22℃; for 24h;	81%

: 21240-56-2
9-methyl-9H-carbazole-3-carbaldehyde

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

: (E)-1-(4-hydroxy-3,5-dimethoxyphenyl)-3-(9-methyl-9H-carbazol-6-yl)prop-2-en-1-one

Conditions

Conditions	Yield
With piperidine In ethanol for 3h; Claisen-Schmidt Condensation; Reflux;	79%

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

: 107-21-1
ethylene glycol

: 926907-08-6
2,6-dimethoxy-4-(2-methyl-[1,3]dioxolan-2-yl)-phenol

Conditions

Conditions	Yield
With toluene-4-sulfonic acid; orthoformic acid triethyl ester	75%

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

: 1189796-80-2
C10H15IO

: C20H25IO5

Conditions

Conditions	Yield
With bis-[(trifluoroacetoxy)iodo]benzene In dichloromethane	69%

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

: 51149-28-1
2-bromo-1-(4-hydroxy-3,5-dimethoxyphenyl)ethanone

Conditions

Conditions	Yield
With copper(ll) bromide In chloroform; ethyl acetate at 20℃; for 21h; Bromination;	68%
With bromine In chloroform
With bromine In 1,4-dioxane; diethyl ether at 0℃; for 1h;

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

: 75-26-3
isopropyl bromide

: 120448-71-7
3',5'-dimethoxy-4'-isopropoxyacetophenone

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide for 4.5h; Heating;	65.9%

: 621-23-8
1,2,3-trimethoxybenzene

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

: 4-(bis(2,4,6-trimethoxyphenyl)methyl)-2,6-dimethoxyphenol

Conditions

Conditions	Yield
Stage #1: 1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone With selenium(IV) oxide; ytterbium(III) chloride In water; dimethyl sulfoxide at 110℃; for 15h; Green chemistry; Stage #2: 1,2,3-trimethoxybenzene In water; dimethyl sulfoxide at 70℃; for 0.166667h; Green chemistry;	65%

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

: 7303-49-3
DL-tryptophan methyl ester

: 1638141-24-8
C22H18N2O6

Conditions

Conditions	Yield
Stage #1: 1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone With iodine; dimethyl sulfoxide at 90℃; Stage #2: DL-tryptophan methyl ester	64%

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

A: 3934-89-2
1-(3,4-dihydroxy-5-methoxyphenyl)-ethan-1-one

B: 33709-29-4
1-(3,4,5-trihydroxyphenyl)-ethan-1-one

Conditions

Conditions	Yield
With methylimidazolium bromide at 110℃; Irradiation;	A 63% B 26%

: 4897-84-1
Methyl 4-bromobutyrate

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

: 159645-64-4
4-(4-Acetyl-2,6-dimethoxy-phenoxy)-butyric acid methyl ester

Conditions

Conditions	Yield
	60%
With 18-crown-6 ether; potassium carbonate In butanone 1.) reflux, 48 h, 2.) reflux, 1 h;	60%

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

: 123-08-0
4-hydroxy-benzaldehyde

: 172302-30-6
1-(4-hydroxy-3,5-dimethoxyphenyl)-3-(4-hydroxyphenyl)-prop-2-enone

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate In dichloromethane at 20℃; for 24h;	60%

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

: 2CF3O2S(1-)*Zn(2+)*2H2O

: 1-[4-hydroxy-3,5-dimethoxy-2-(trifluoromethyl)phenyl]ethan-1-one

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; copper(l) iodide; hydroquinone In water; dimethyl sulfoxide at 30℃; for 24h; pH=5.5; Catalytic behavior; Reagent/catalyst; Solvent; Sealed tube;	58%

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

: 1189796-72-2
(E)-2-allyl-6-iodohepta-2,6-dienoic acid

: 1189796-73-3
C20H23IO6

Conditions

Conditions	Yield
Stage #1: (E)-2-allyl-6-iodohepta-2,6-dienoic acid With diphenic acid; lead(IV) tetraacetate In dichloromethane at 0 - 20℃; Inert atmosphere; Stage #2: 1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone In dichloromethane at 0 - 20℃; for 2.25h;	54%

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

: (E)-2-allyl-6-bromohepta-2,6-dienoic acid

: 1189796-74-4
C20H23BrO6

Conditions

Conditions	Yield
Stage #1: (E)-2-allyl-6-bromohepta-2,6-dienoic acid With diphenic acid; lead(IV) tetraacetate In dichloromethane for 0.333333h; Inert atmosphere; Stage #2: 1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone In dichloromethane at 0 - 20℃; for 1.41667h;	48%

: 621-59-0
isovanillin

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

: 1197288-80-4
(E)-1-(4-hydroxy-3,5-dimethoxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)prop-2-en-1-one

Conditions

Conditions	Yield
Stage #1: isovanillin; 1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone In ethanol at 20℃; for 0.0833333h; Stage #2: With sodium hydroxide In ethanol at 20℃;	48%

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

: 122795-89-5
phenyl 2,3,4,6-tetra-O-benzyl-1-sulfinyl-α/β-D-glucopyranoside

: 1-[3,5-Dimethoxy-4-((2R,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yloxy)-phenyl]-ethanone

Conditions

Conditions	Yield
With 2,6-di-tert-butyl-4-methylpyridine In dichloromethane at 20℃;	46%

: 2478-38-8
1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone

: C11H17IO2

: C21H27IO6

Conditions

Conditions	Yield
With 1,1,1,3',3',3'-hexafluoro-propanol; bis-[(trifluoroacetoxy)iodo]benzene In dichloromethane at 20℃; for 2.5h; Inert atmosphere;	34%

Acetosyringone Specification

The Acetosyringone, with CAS registry number 2478-38-8, belongs to the following product category: Aromatic Acetophenones & Derivatives (substituted). Its systematic name and its IUPAC name are the same, which is 1-(4-hydroxy-3,5-dimethoxyphenyl)ethanone. And this chemical is a kind of beige to light brown crystalline powder.

Physical properties of Acetosyringone are: (1)ACD/LogP: 1.699; (2)ACD/LogD (pH 5.5): 1.70; (3)ACD/LogD (pH 7.4): 1.63; (4)ACD/BCF (pH 5.5): 11.49; (5)ACD/BCF (pH 7.4): 9.92; (6)ACD/KOC (pH 5.5): 199.64; (7)ACD/KOC (pH 7.4): 172.35; (8)#H bond acceptors: 4; (9)#H bond donors: 1; (10)#Freely Rotating Bonds: 4; (11)Index of Refraction:1.528; (12)Molar Refractivity: 51.519 cm³; (13)Molar Volume: 167.398 cm³; (14)Polarizability: 20.424 10-24cm³; (15)Surface Tension: 39.9329986572266 dyne/cm; (16)Density: 1.172 g/cm³; (17)Flash Point: 131.705 °C; (18)Enthalpy of Vaporization: 60.054 kJ/mol; (19)Boiling Point: 334.653 °C at 760 mmHg

Preparation of Acetosyringone: This chemical can be prepared by 1-(3,4,5-trimethoxy-phenyl)-ethanone. This reaction will need reagent AlCl_3. The yield is about 60%.

Preparation of Acetosyringone

Uses of Acetosyringone: It can be used to produce 3',5'-dimethoxy-4'-isopropoxyacetophenone. This reaction will need reagent K₂CO₃ and solvent dimethylformamide. The reaction time is 4.5 hour(s). The yield is about 65.9%.

When you are using this chemical, please be cautious about it as the following:
The Acetosyringone irritates to eyes, respiratory system and skin. When use it, wear suitable protective clothing, gloves and eye/face protection. If contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)InChI=1S/C10H12O4/c1-6(11)7-4-8(13-2)10(12)9(5-7)14-3/h4-5,12H,1-3H3;
(2)InChIKey=OJOBTAOGJIWAGB-UHFFFAOYSA-N;
(3)Smilesc1(c(c(cc(c1)C(C)=O)OC)O)OC;

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	650mg/kg (650mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)	Journal of Medicinal Chemistry. Vol. 7, Pg. 178, 1964.
mouse	LD50	oral	> 10gm/kg (10000mg/kg)		Bromatologia i Chemia Toksykologiczna. Vol. 14, Pg. 301, 1981.

Product Name

Acetosyringone

Synthetic route

Acetosyringone Specification

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