-
Name
Arbidol
- EINECS 814-571-6
- CAS No. 131707-25-0
- Article Data5
- CAS DataBase
- Density 1.375 g/cm3
- Solubility
- Melting Point
- Formula C22H25BrN2O3S
- Boiling Point 591.776 °C at 760 mmHg
- Molecular Weight 477.422
- Flash Point 311.695 °C
- Transport Information
- Appearance White to off-white crystalline powder
- Safety
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms Ethyl 6-bromo-5-hydroxy-1-methyl-4-((dimethylamino)methyl)-2-[(phenylthio)methyl]-1H-indole-3-carboxylate;ethyl 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylsulfanyl)methyl]-1H-indole-3-carboxylate;
- PSA 80.00000
- LogP 5.17700
Arbidol Chemical Properties
Molecular Formula: C22H25BrN2O3S
Molecular Weight: 531.89
Density: 1.37 g/cm3
Flash Point: 311.7 °C
Index of Refraction: 1.619
CAS Registry Number: 131707-25-0
Enthalpy of Vaporization: 91.52 kJ/mol
Boiling Point: 591.8 °C at 760 mmHg
Vapour Pressure: 1.34E-14 mmHg at 25°C
IUPAC: Ethyl 6-bromo-4-(dimethylaminomethyl)-5-hydroxy-1-methyl-2-(phenylsulfanylmethyl)indole-3-carboxylate
Synonyms: Ethyl6-bromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl. ; Arbidol ; Ethyl 6-bromo-5-hydroxy-1-methyl-4-((dimethylamino)methyl)-2-[(phenylthio)methyl]-1H-indole-3-carboxylate ; Intermediate:Arbidolhydrochloride
Following is the molecular structure of Arbidol (CAS NO.131707-25-0):
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Arbidol Uses
Clinical application of Arbidol (CAS NO.131707-25-0):
Arbidol is used primarily as an antiviral treatments for influenza. It is compared most with oseltamivir.
The drug has also been investigated as a candidate drug for treatment of hepatitis C.
Arbidol Specification
Arbidol (CAS NO.131707-25-0) is an antiviral treatment for influenza infection used in Russia and China. The drug is manufactured by Moscow-based Masterlek. Its acceptance amongst the pharamecutical industry varies, although some Russian studies have shown it to be as effective as other available treatments.
Chemically, Arbidol features an indole core, functionalized at all positions but one with different substituents. The drug inhibits viral entry into target cells, and also stimulates the immune response.
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