Product Name

  • Name

    Biphenyl-4,4'-dicarboxylic acid

  • EINECS 212-328-3
  • CAS No. 787-70-2
  • Article Data75
  • CAS DataBase
  • Density 1.347 g/cm3
  • Solubility
  • Melting Point >300 °C(lit.)
  • Formula C14H10O4
  • Boiling Point 482.5 °C at 760 mmHg
  • Molecular Weight 242.231
  • Flash Point 259.7 °C
  • Transport Information
  • Appearance White to light beige powder
  • Safety 26-37/39-36
  • Risk Codes 36/37/38-20/21/22
  • Molecular Structure Molecular Structure of 787-70-2 (Biphenyl-4,4'-dicarboxylic acid)
  • Hazard Symbols HarmfulXn, IrritantXi
  • Synonyms 4,4'-Biphenyldicarboxylicacid (6CI,7CI,8CI);4,4'-Bibenzoic acid;4,4'-Dicarboxybiphenyl;4,4'-Diphenicacid;4,4'-Diphenyldicarboxylic acid;NSC 60016;p,p'-Diphenic acid;[1,1'-Biphenyl]-4,4'-dicarboxylicacid;
  • PSA 74.60000
  • LogP 2.75000

Synthetic route

(4,4'-dimethyl-1,1'-biphenyl)
613-33-2

(4,4'-dimethyl-1,1'-biphenyl)

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
With oxygen; acetic anhydride for 17h; Reflux; Large scale; Green chemistry;98.6%
With acetic acid In water at 190℃; under 11103.3 Torr; for 3h;93.1%
With chromium; acetic acid
4,4'-biphenyldicarboxylic acid dimethyl ester
792-74-5

4,4'-biphenyldicarboxylic acid dimethyl ester

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
With sulfuric acid In water; acetic acid at 120℃; for 24h; Reflux;96.6%
With sodium hydroxide In tetrahydrofuran; water at 80℃; for 48h; Reflux;88%
4,4'-bis(trichloromethyl)biphenyl
30061-79-1

4,4'-bis(trichloromethyl)biphenyl

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
With water; sodium hydroxide for 10h; Temperature; Reflux;95.6%
With water
4-Bromobenzoic acid
586-76-5

4-Bromobenzoic acid

4-carboxyphenylboronic acid
14047-29-1

4-carboxyphenylboronic acid

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
With 4-(di-tert-butylphosphino)ethyltrimethylammonium chloride; sodium carbonate; sodium tetrachloropalladate(II) In water at 20℃; Suzuki reaction;94%
With Na2[Pd(BuHSS)]; caesium carbonate In water at 80℃; for 2h; Suzuki-Miyaura Coupling; Sealed tube; Green chemistry;92%
With tetrabutylammomium bromide; sodium carbonate In water at 150℃; for 0.0833333h; Suzuki reaction; microwave irradiation;
4-iodobenzoic acid
619-58-9

4-iodobenzoic acid

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
With indium; tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 100℃; for 4h;91.7%
With [Pd{C6H4(CH2N(CH2Ph)2)}(μ-Br)]2; potassium carbonate In 1-methyl-pyrrolidin-2-one at 130℃; for 14h; Microwave irradiation;88%
With sodium hydroxide; ammonium formate; zinc In methanol for 2.5h; Heating;82%
carbon dioxide
124-38-9

carbon dioxide

4-(4-bromophenyl)bromobenzene
92-86-4

4-(4-bromophenyl)bromobenzene

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
Stage #1: carbon dioxide With o-phenylenebis(diphenylphosphine); copper(II) acetate monohydrate In 1,4-dioxane at 65℃; for 0.333333h; Schlenk technique;
Stage #2: 4-(4-bromophenyl)bromobenzene With palladium diacetate; triethylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In 1,4-dioxane; toluene at 100℃; for 16h; Schlenk technique; Sealed tube;
91%
Stage #1: carbon dioxide With o-phenylenebis(diphenylphosphine); copper(II) acetate monohydrate In 1,4-dioxane at 65℃; for 0.416667h; Schlenk technique;
Stage #2: 4-(4-bromophenyl)bromobenzene With palladium diacetate; triethylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In 1,4-dioxane; toluene at 100℃; for 16h; Schlenk technique;
91%
4-iodobenzoic acid
619-58-9

4-iodobenzoic acid

4-carboxyphenylboronic acid
14047-29-1

4-carboxyphenylboronic acid

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); Davisil 500 Angstroem beads; sodium carbonate In water for 0.0833333h; Suzuki cross coupling reaction; Heating;86%
With potassium carbonate In water Suzuki-Miyaura reaction; Heating;
para-chlorobenzoic acid
74-11-3

para-chlorobenzoic acid

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
With pyridine; samarium; copper(l) chloride In water at 20℃; for 17h; Ionic liquid;81%
With triethylamine; palladium dichloride at 80℃; for 20h;80%
With sodium hydroxide; 10%-palladium on charcoal In water50%
4-Bromobenzoic acid
586-76-5

4-Bromobenzoic acid

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
With [Pd{C6H4(CH2N(CH2Ph)2)}(μ-Br)]2; potassium carbonate In 1-methyl-pyrrolidin-2-one at 130℃; for 30h; Microwave irradiation;80%
With ethylenediaminetetraacetic acid; potassium carbonate; ascorbic acid In ethanol; water for 9h; Heating;70%
With tetrabutylammonium tetrafluoroborate In N,N-dimethyl-formamide at 20℃; for 6h; Electrochemical reaction;58%
With potassium hydroxide; palladium on activated charcoal; Lindlar's catalyst; hydrazine hydrate at 140℃;
With bis(triphenylphosphine)nickel(0) dicarbonyl In dimethyl sulfoxide at 70℃; for 6h;70 % Chromat.
potassium (4-(methoxycarbonyl)phenyl)trifluoroborate
705254-34-8

potassium (4-(methoxycarbonyl)phenyl)trifluoroborate

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
With Pd(np)/Te-Dps; water at 100℃; for 24h; pH=8.9; Aerobic conditions; aq. Tris-HCl buffer; Combinatorial reaction / High throughput screening (HTS);60%
n-butyllithium
109-72-8, 29786-93-4

n-butyllithium

4-(4-bromophenyl)bromobenzene
92-86-4

4-(4-bromophenyl)bromobenzene

A

4-(4-bromophenyl)benzoic acid
5731-11-3

4-(4-bromophenyl)benzoic acid

B

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
With diethyl ether anschliessendes Behandeln mit Kohlendioxid;
(1,1'-biphenyl)-4,4'-dicarbonitrile
1591-30-6

(1,1'-biphenyl)-4,4'-dicarbonitrile

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
With sulfuric acid
With hydrogenchloride at 180℃;
4,4'-bis(trifluoromethyl)biphenyl
581-80-6

4,4'-bis(trifluoromethyl)biphenyl

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
With sulfuric acid
4-Bromobenzoic acid
586-76-5

4-Bromobenzoic acid

A

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

B

benzoic acid
65-85-0

benzoic acid

Conditions
ConditionsYield
With potassium hydroxide; palladium on activated charcoal Hydrogenation;
4'-methyl-biphenyl-4-carboxylic acid
720-73-0

4'-methyl-biphenyl-4-carboxylic acid

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
With permanganate(VII) ion
4,4'-dichlorobiphenyl
2050-68-2

4,4'-dichlorobiphenyl

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
With magnesium anschliessend Behandeln mit CO2;
4-(4-bromophenyl)bromobenzene
92-86-4

4-(4-bromophenyl)bromobenzene

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
With n-butyllithium; Petroleum ether Behandeln des von Petrolaether befreiten Reaktionsgemisches mit festem Kohlendioxid;
4,4'-diacetylbiphenyl
787-69-9

4,4'-diacetylbiphenyl

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
With potassium hypochlorite
With manganese(II) nitrate; oxygen; cobalt(II) nitrate In acetic acid at 100℃; for 6h;
With nitric acid; acetic acid for 144h; Reflux;
4-4'-bis(bromomethyl)biphenyl
20248-86-6

4-4'-bis(bromomethyl)biphenyl

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
With nitric acid
4,4'-Bis(1-chloro-1-methylol-2-ethenyl)biphenyl
77443-75-5

4,4'-Bis(1-chloro-1-methylol-2-ethenyl)biphenyl

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
With potassium hydroxide; potassium permanganate In water for 8h; Product distribution; Heating;
(Z)-3-[4'-((Z)-2-Carboxy-2-chloro-vinyl)-biphenyl-4-yl]-2-chloro-acrylic acid
77443-80-2

(Z)-3-[4'-((Z)-2-Carboxy-2-chloro-vinyl)-biphenyl-4-yl]-2-chloro-acrylic acid

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
With potassium hydroxide; potassium permanganate In water Product distribution;
1-(4'-(1-methylethyl)biphenyl-4-yl)ethanone
102714-30-7

1-(4'-(1-methylethyl)biphenyl-4-yl)ethanone

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
(oxidation);
p.p'-Bis(2-cyanovinyl)biphenyl
42094-75-7

p.p'-Bis(2-cyanovinyl)biphenyl

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
With potassium permanganate
4-iodobenzoic acid
619-58-9

4-iodobenzoic acid

A

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

B

benzoic acid
65-85-0

benzoic acid

Conditions
ConditionsYield
With M2PtCl4 In N,N-dimethyl-formamide at 80℃; Kinetics; Substitution; oxidative coupling;
dipotassium-salt of/the/ diphenic acid

dipotassium-salt of/the/ diphenic acid

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
With carbon dioxide; cadmium(II) oxide at 380℃;
(4,4'-dimethyl-1,1'-biphenyl)
613-33-2

(4,4'-dimethyl-1,1'-biphenyl)

aqueous KMnO4-solution

aqueous KMnO4-solution

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

(4,4'-dimethyl-1,1'-biphenyl)
613-33-2

(4,4'-dimethyl-1,1'-biphenyl)

acetic acid
64-19-7

acetic acid

CrO3

CrO3

A

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

B

p-tolyl-benzoic acid

p-tolyl-benzoic acid

ethanol
64-17-5

ethanol

4-(4-bromophenyl)bromobenzene
92-86-4

4-(4-bromophenyl)bromobenzene

potassium cyanide
151-50-8

potassium cyanide

NiCl2

NiCl2

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
at 260 - 270℃;
4-Bromobenzoic acid
586-76-5

4-Bromobenzoic acid

hydrazine hydrate
7803-57-8

hydrazine hydrate

methanol. KOH-solution

methanol. KOH-solution

palladium/calcium carbonate

palladium/calcium carbonate

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Conditions
ConditionsYield
at 140℃;
4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

4,4'-biphenyldicarboxylic acid dichloride
2351-37-3

4,4'-biphenyldicarboxylic acid dichloride

Conditions
ConditionsYield
With thionyl chloride for 3h; Reflux;100%
With thionyl chloride; betaine In 1,2-dichloro-ethane for 17h; Heating; other catalysts;96%
With oxalyl dichloride In N,N-dimethyl-formamide for 18h;93%
guanidine hydrogen carbonate
124-46-9, 20734-13-8, 100224-74-6, 593-85-1

guanidine hydrogen carbonate

tetra(n-butyl)ammonium hydroxide
2052-49-5

tetra(n-butyl)ammonium hydroxide

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

3C14H8O4(2-)*6C16H36N(1+)*6CH5N3*6CH2O3

3C14H8O4(2-)*6C16H36N(1+)*6CH5N3*6CH2O3

Conditions
ConditionsYield
for 0.0833333h;100%
4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

sodium (1,1'-biphenyl)-4,4'-dicarboxylate

sodium (1,1'-biphenyl)-4,4'-dicarboxylate

Conditions
ConditionsYield
With sodium hydroxide In water100%
With sodium hydroxide In water at 20℃;71%
4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

C14H8O4(2-)*2Rb(1+)

C14H8O4(2-)*2Rb(1+)

Conditions
ConditionsYield
With rubidium hydroxide In water100%
4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

C14H8O4(2-)*2Cs(1+)

C14H8O4(2-)*2Cs(1+)

Conditions
ConditionsYield
With cesium hydroxide In water100%
4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

lithium [1,1'-biphenyl]-4,4'-dicarboxylate

lithium [1,1'-biphenyl]-4,4'-dicarboxylate

Conditions
ConditionsYield
With lithium hydroxide In water100%
With lithium hydroxide monohydrate In ethanol at 60℃; for 12h;93%
With lithium hydroxide monohydrate In methanol for 1h; Solvent;
4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

biphenyl-4,4’-dicarboxylic acid dipotassium salt

biphenyl-4,4’-dicarboxylic acid dipotassium salt

Conditions
ConditionsYield
With potassium hydroxide In water100%
tetra(n-butyl)ammonium hydroxide
2052-49-5

tetra(n-butyl)ammonium hydroxide

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

tetrabutylammonium 4,4'-biphenyldicarboxylate

tetrabutylammonium 4,4'-biphenyldicarboxylate

Conditions
ConditionsYield
In methanol; ethanol100%
[2,2]bipyridinyl
366-18-7

[2,2]bipyridinyl

zinc(II) nitrate hexahydrate

zinc(II) nitrate hexahydrate

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

{[Zn(4,4'-biphenyldicarboxylato)(2,2'-bipyridine)]·2N,N-dimethylformamide}n

{[Zn(4,4'-biphenyldicarboxylato)(2,2'-bipyridine)]·2N,N-dimethylformamide}n

Conditions
ConditionsYield
at 80℃; for 96 - 168h;100%
2,2-bis(4-phenoxyphenyl)hexafluoropropane
24546-39-2

2,2-bis(4-phenoxyphenyl)hexafluoropropane

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

polymer, inherent viscosity 0.1% in sulfuric acid at 25 deg C 0.75 dl/g; monomer(s): 2,2-bis(4-phenoxyphenyl)hexafluoropropane; biphenyl-4,4'-dicarboxylic acid

polymer, inherent viscosity 0.1% in sulfuric acid at 25 deg C 0.75 dl/g; monomer(s): 2,2-bis(4-phenoxyphenyl)hexafluoropropane; biphenyl-4,4'-dicarboxylic acid

Conditions
ConditionsYield
With trifluorormethanesulfonic acid at 25℃; for 26h;99%
4,4'-bipyridine
553-26-4

4,4'-bipyridine

cobalt(II) nitrate hexahydrate

cobalt(II) nitrate hexahydrate

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

Co3(4,4'-biphenyldicarboxylate)3(4,4'-bipyridine)*4(N,N-dimethylformamide)*H2O

Co3(4,4'-biphenyldicarboxylate)3(4,4'-bipyridine)*4(N,N-dimethylformamide)*H2O

Conditions
ConditionsYield
In N,N-dimethyl-formamide High Pressure; solvothermal reaction; mixt. of Co salt, 4,4'-bipyridine, and dicarboxylic acid in DMF heated at 150°C for 3 d; elem. anal.;99%
In N,N-dimethyl-formamide High Pressure; mixt. of Co(NO3)2*6H2O, dicarboxylic acid, 4,4'-bipyridine in DMF heatedat 150°C for 48 h in Teflon-lined autoclave, cooled to room temp .; crystals filtered off, washed with DMF, dried at 80°C for 3 h;
tetramethyl ammoniumhydroxide
75-59-2

tetramethyl ammoniumhydroxide

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

bis(tetramethylammonium) 4,4′-biphenyl dicarboxylate

bis(tetramethylammonium) 4,4′-biphenyl dicarboxylate

Conditions
ConditionsYield
In methanol at 21℃; for 48h;98%
(3S,4S)-N3,N4-bis(4-fluorophenethyl)pyrrolidine-3,4-dicarboxamide hydrochloride

(3S,4S)-N3,N4-bis(4-fluorophenethyl)pyrrolidine-3,4-dicarboxamide hydrochloride

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

(3S,3’S,4S,4’S)-1,1’-([1,1’-biphenyl]-4,4’-dicarbonyl)bis(N3,N4-bis (4-fluorophenethyl)pyrrolidine-3,4-dicarboxamide)

(3S,3’S,4S,4’S)-1,1’-([1,1’-biphenyl]-4,4’-dicarbonyl)bis(N3,N4-bis (4-fluorophenethyl)pyrrolidine-3,4-dicarboxamide)

Conditions
ConditionsYield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 23℃;98%
tetramethyl ammoniumhydroxide
75-59-2

tetramethyl ammoniumhydroxide

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

bis(tetramethylammonium) 2,6-naphthalenedicarboxylate

bis(tetramethylammonium) 2,6-naphthalenedicarboxylate

Conditions
ConditionsYield
In methanol at 21℃; for 48h;98%
4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

2,8-Diphenoxydibenzofuran
121073-96-9

2,8-Diphenoxydibenzofuran

polymer, inherent viscosity 0.1% in sulfuric acid at 25 deg C 0.76 dl/g; monomer(s): 2,8-diphenoxydibenzofuran; biphenyl-4,4'-dicarboxylic acid

polymer, inherent viscosity 0.1% in sulfuric acid at 25 deg C 0.76 dl/g; monomer(s): 2,8-diphenoxydibenzofuran; biphenyl-4,4'-dicarboxylic acid

Conditions
ConditionsYield
With trifluorormethanesulfonic acid at 25℃; for 26h;96%
(3S,4S)-N3,N4-bis(((1S,2R)-2-phenylcyclopropyl)carbamoyl)pyrrolidine-3,4-dicarboxamide hydrochloride

(3S,4S)-N3,N4-bis(((1S,2R)-2-phenylcyclopropyl)carbamoyl)pyrrolidine-3,4-dicarboxamide hydrochloride

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

(3S,3’S,4S,4’S)-1,1’-(4,4’-biphenyldicarboxoyl)-bis(N3,N4-bis((1S,2R)-2-phenylcyclopropyl)pyrrolidine-3,4-dicarboxamide)

(3S,3’S,4S,4’S)-1,1’-(4,4’-biphenyldicarboxoyl)-bis(N3,N4-bis((1S,2R)-2-phenylcyclopropyl)pyrrolidine-3,4-dicarboxamide)

Conditions
ConditionsYield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 23℃; for 18h;96%
methanol
67-56-1

methanol

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

4,4'-biphenyldicarboxylic acid dimethyl ester
792-74-5

4,4'-biphenyldicarboxylic acid dimethyl ester

Conditions
ConditionsYield
Stage #1: 4,4'-diphenic acid With thionyl chloride Reflux;
Stage #2: methanol at 0℃;
95%
With phosphorus pentachloride
Stage #1: 4,4'-diphenic acid With thionyl chloride Reflux;
Stage #2: methanol at 0℃;
With sulfuric acid Reflux;
4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

1,1'-carbonyldiimidazole
530-62-1

1,1'-carbonyldiimidazole

1,1'-(4,4'-dibenzoyl)diimidazole

1,1'-(4,4'-dibenzoyl)diimidazole

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 67 - 69℃; for 0.25h; Inert atmosphere;95%
4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

methyl iodide
74-88-4

methyl iodide

4,4'-biphenyldicarboxylic acid dimethyl ester
792-74-5

4,4'-biphenyldicarboxylic acid dimethyl ester

Conditions
ConditionsYield
With potassium carbonate In acetone at 70℃; for 24h; Sealed tube;95%
zirconium(IV) chloride
10026-11-6

zirconium(IV) chloride

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

[Zr6O4(OH)4(4,4′-biphenyldicarboxylate)6]

[Zr6O4(OH)4(4,4′-biphenyldicarboxylate)6]

Conditions
ConditionsYield
With acetic acid In N,N-dimethyl-formamide at 120℃; for 24h; High pressure;94%
With benzoic acid In N,N-dimethyl-formamide at 120℃; for 120h; Inert atmosphere; Schlenk technique;
With benzoic acid In N,N-dimethyl-formamide at 120℃; for 24h;
cadmium(II) nitrate tetrhydrate

cadmium(II) nitrate tetrhydrate

N-(pyridin-4-yl)-4-(pyridin-4-yl)-1,8-naphthalimide

N-(pyridin-4-yl)-4-(pyridin-4-yl)-1,8-naphthalimide

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

[Cd2(biphenyl-4,4’-dicarboxylate)2(N-(pyridin-4-yl)-4-(pyridin-4-yl)-1,8-naphthalimide)2]*2.5DMF*3.5H2O

[Cd2(biphenyl-4,4’-dicarboxylate)2(N-(pyridin-4-yl)-4-(pyridin-4-yl)-1,8-naphthalimide)2]*2.5DMF*3.5H2O

Conditions
ConditionsYield
at 100℃; for 48h;94%
aluminum(III) nitrate nonahydrate

aluminum(III) nitrate nonahydrate

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Al(2,2’-bipyridine-5,5’-dicarboxylic acid-2H)(OH)
1207564-78-0

Al(2,2’-bipyridine-5,5’-dicarboxylic acid-2H)(OH)

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 120℃; for 24h;93.2%
In N,N-dimethyl-formamide at 119.84℃; for 48h; Sealed tube; Autoclave;
In N,N-dimethyl-formamide at 120℃; for 24h;
In N,N-dimethyl-formamide at 120℃; for 0.5h; Autoclave; Microwave irradiation;
4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

3-(4-tert-butyl-2,6-diiodo-phenoxy)-propan-1-ol

3-(4-tert-butyl-2,6-diiodo-phenoxy)-propan-1-ol

Bis[3-(4-tert-butyl-2,6-diiodophenoxy)propyl] 4,4'-biphenyldicarboxylate

Bis[3-(4-tert-butyl-2,6-diiodophenoxy)propyl] 4,4'-biphenyldicarboxylate

Conditions
ConditionsYield
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 20℃; for 1h; Esterification;93%
4,4'-sulfonylbis(phenoxybenzene)
1623-91-2

4,4'-sulfonylbis(phenoxybenzene)

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

polymer, inherent viscosity 0.1% in sulfuric acid at 25 deg C 0.73 dl/g; monomer(s): 4,4'-diphenoxydiphenylsulfone; biphenyl-4,4'-dicarboxylic acid

polymer, inherent viscosity 0.1% in sulfuric acid at 25 deg C 0.73 dl/g; monomer(s): 4,4'-diphenoxydiphenylsulfone; biphenyl-4,4'-dicarboxylic acid

Conditions
ConditionsYield
With trifluorormethanesulfonic acid at 25℃; for 26h;92%
4,4'-bipyridine
553-26-4

4,4'-bipyridine

zinc(II) nitrate
10196-18-6

zinc(II) nitrate

4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

Zn3(4,4'-biphenyl dicarboxylate)3(4,4'-dipyridyl)

Zn3(4,4'-biphenyl dicarboxylate)3(4,4'-dipyridyl)

Conditions
ConditionsYield
In DMF (N,N-dimethyl-formamide) at 150℃; for 72h;92%
4,4'-diphenic acid
787-70-2

4,4'-diphenic acid

cobalt(II) nitrate

cobalt(II) nitrate

[Co(4,4′-biphenyldicarboxylate)(H2O)2]

[Co(4,4′-biphenyldicarboxylate)(H2O)2]

Conditions
ConditionsYield
Stage #1: 4,4'-diphenic acid With sodium hydroxide In water at 80℃; for 1h;
Stage #2: cobalt(II) nitrate In water at 25℃;
92%

Biphenyl-4,4'-dicarboxylic acid Chemical Properties

IUPAC Name: 4-(4-Carboxyphenyl)benzoic acid
Following is the structure of Biphenyl-4,4'-dicarboxylic acid (CAS NO.787-70-2):
                 
Empirical Formula: C14H10O4
Molecular Weight: 242.2268
Index of Refraction: 1.639
Molar Refractivity: 64.7 cm3
Molar Volume: 179.7 cm3
Density: 1.347 g/cm3
Flash Point: 259.7 °C
Melting point: >300 °C(lit.)
Surface Tension: 62.2 dyne/cm
Enthalpy of Vaporization: 78.73 kJ/mol
Boiling Point: 482.5 °C at 760 mmHg
Vapour Pressure: 4.02E-10 mmHg at 25 °C
Appearance of Biphenyl-4,4'-dicarboxylic acid (CAS NO.787-70-2): White to light beige powder
Product Categories: Industrial/Fine Chemicals; Biphenyl derivatives; Biphenyl & Diphenyl ether; Biphenyls (for High-Performance Polymer Research); Functional Materials; Reagent for High-Performance Polymer Research; Carboxylic Acid Monomers; Monomers; Polymer Science; API's
Canonical SMILES: C1=CC(=CC=C1C2=CC=C(C=C2)C(=O)O)C(=O)O
InChI: InChI=1S/C14H10O4/c15-13(16)11-5-1-9(2-6-11)10-3-7-12(8-4-10)14(17)18/h1-8H,(H,15,16)(H,17,18)
InChIKey: NEQFBGHQPUXOFH-UHFFFAOYSA-N

Biphenyl-4,4'-dicarboxylic acid Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 500mg/kg (500mg/kg)   National Technical Information Service. Vol. AD277-689,

Biphenyl-4,4'-dicarboxylic acid Safety Profile

Hazard Codes: IrritantXi,HarmfulXn
Risk Statements: 36/37/38-20/21/22 
R36/37/38:Irritating to eyes, respiratory system and skin. 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-37/39-36 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S37/39:Wear suitable gloves and eye/face protection. 
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: DV2975000

Biphenyl-4,4'-dicarboxylic acid Specification

 Biphenyl-4,4'-dicarboxylic acid , its cas register number 787-70-2. It also can be called 4,4'-Biphenyldicarboxylic acid ; (1,1'-Biphenyl)-4,4'-dicarboxylic acid ; 4,4'-Bibenzoic acid ; 4,4'-Dicarboxybiphenyl ; 4,4'-Diphenic acid ; and p,p'-Diphenic acid .

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