Chloroplatinic acid

Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

OSHA PEL: TWA 0.002 mg(Pt)/m³
ACGIH TLV: TWA 0.002 mg(Pt)/m³
DOT Classification:  8; Label: Corrosive

The Chloroplatinic acid, with the CAS registry number 16941-12-1 and EINECS registry number 241-010-7, has the systematic name of dihydrogen hexachloroplatinate(2-). The molecular formula of this chemical is H₂PtCl₆. It is a kind of orange or red crystals, and may decompose on exposure to light, air or moisture. What's more, it  is the chemical compound usually found as the hexahydrate with the formula H₂PtCl₆^.(H₂O)₆. And it is one of the most readily available soluble compounds of platinum.

The physical properties of Chloroplatinic acid are as following: (1)ACD/LogP: -1.03; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -5.53; (4)ACD/LogD (pH 7.4): -5.53; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1 ; (7)#H bond acceptors: 4; (8)#H bond donors: 2; (9)#Freely Rotating Bonds: 0; (10)Polar Surface Area: 82.98 Å²; (11)Enthalpy of Vaporization: 62.94 kJ/mol; (12)Boiling Point: 330 °C at 760 mmHg; (13)Vapour Pressure: 3.35E-05 mmHg at 25°C.

Preparation of Chloroplatinic acid: It can be produced by dissolving platinum metal sponge in aqua regia. This reaction is rumored to produce nitrogen-containing platinum compounds, but the product is H₂PtCl₆.
Pt + 4HNO₃ + 6 HCl → H₂PtCl₆ + 4NO₂ + 4H₂O

Uses of Chloroplatinic acid: It is often used in the potassium determination, purification of platinum, and it is also used as a catalyst precursor in some organic synthesis.

You should be cautious while dealing with this chemical. It is toxic if swallowed, and may cause burns. It may also cause sensitization by inhalation and skin contact. Therefore, you had better take the following instructions: Do not breathe dust; Wear suitable protective clothing, gloves and eye/face protection, and in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice; In case of accident or if you feel unwell, seek medical advice immediately (show label where possible).

You can still convert the following datas into molecular structure:
(1)SMILES: [H+].[H+].Cl[Pt-2](Cl)(Cl)(Cl)(Cl)Cl
(2)InChI: InChI=1/6ClH.Pt/h6*1H;/q;;;;;;+4/p-4/rCl6Pt/c1-7(2,3,4,5)6/q-2/p+2
(3)InChIKey: GBFHNZZOZWQQPA-DUMOQKOKAQ

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	29097mg/kg (29097mg/kg)		Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 256, Pg. 1043, 1963.
rabbit	LDLo	intravenous	125mg/kg (125mg/kg)		Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
rat	LD50	intravenous	49mg/kg (49mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION BEHAVIORAL: TREMOR GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	National Technical Information Service. Vol. PB291-731.