Product Name

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  • Name

    S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O

  • EINECS
  • CAS No. 5653-80-5
  • Article Data6
  • CAS DataBase
  • Density 1.009g/cm3
  • Solubility
  • Melting Point 100.5°C
  • Formula C21H27 N O
  • Boiling Point 423.7°C at 760 mmHg
  • Molecular Weight 309.451
  • Flash Point 126.5°C
  • Transport Information
  • Appearance
  • Safety Poison by ingestion, subcutaneous, and intraperitoneal routes. Experimental reproductive effects. Mutation data reported. Addictive. When heated to decomposition it emits toxic fumes of NOx. See also METHADONE.
  • Risk Codes
  • Molecular Structure Molecular Structure of 5653-80-5 (S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O)
  • Hazard Symbols
  • Synonyms 3-Heptanone,6-(dimethylamino)-4,4-diphenyl-, (S)- (8CI); (+)-(6S)-Methadone;(+)-(S)-Methadone; (+)-Methadone; (6S)-Methadone; (S)-(+)-Methadone;Dextromethadone; L-(+)-Methadone; L-Methadone; Methadone, (+)-; S-Methadone;d-Methadone
  • PSA 20.31000
  • LogP 4.29200

Dextromethadone Chemical Properties

Chemical Name: S(+)-Methadone hydrochloride inactive en antiomer o
IUPAC NAME: 6-(Dimethylamino)-4,4-diphenylheptan-3-one
CAS No.: 5653-80-5
RTECS: MJ6000000
Molecular Formula: C21H27NO
Molecular Weight: 309.45 g/mol
Density: 1.009 g/cm3 
Flash Point: 126.5 °C
Boiling Point: 423.7 °C at 760 mmHg
Following is the structure of Dextromethadone (5653-80-5):


The chemical synonymous of Dextromethadone (5653-80-5) are s(+)-Methadone hydrochloride inactive en antiomer o ; (s)-6-(Dimethylamino)-4,4-diphenyl-3-heptanone ; 4-Diphenyl-6-(dimethylamino)-(s)-3-heptanon ; 6s-Methadone ; d-6-(Dimethylamino)-4,4-diphenyl-3-heptanone ; Dextromethadone ; d-Methadone ; l-(+)-Methadone

Dextromethadone Toxicity Data With Reference

1.    

dni-rat:tes 50 µmol/L

    BCPCA6    Biochemical Pharmacology. 27 (1978),123.
2.    

oms-rat:tes 50 µmol/L

    BCPCA6    Biochemical Pharmacology. 27 (1978),123.
3.    

orl-mus LD50:252 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 110 (1954),135.
4.    

ipr-mus LD50:74 mg/kg

    BJPCAL    British Journal of Pharmacology and Chemotherapy. 9 (1954),280.
5.    

scu-mus LD50:80 mg/kg

    BJPCAL    British Journal of Pharmacology and Chemotherapy. 9 (1954),280.

Dextromethadone Safety Profile

Poison by ingestion, subcutaneous, and intraperitoneal routes. Experimental reproductive effects. Mutation data reported. Addictive. When heated to decomposition it emits toxic fumes of NOx. See also METHADONE.
Hazard Codes:
Xn: Harmful
Risk Statements about Dextromethadone (5653-80-5):
R22 Harmful if swallowed.
R42/43: May cause sensitization by inhalation and skin contact.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements about Dextromethadone (5653-80-5):
S22 Do not breathe dust.
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.

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