Diethylamine supplier | CasNO.109-89-7

Name
Diethylamine
EINECS 203-716-3
CAS No. 109-89-7
Article Data472
CAS DataBase
Density 0.7074 g/cm³
Solubility miscible with water
Melting Point -50 °C
Formula C₄H₁₁N
Boiling Point 57.3 °C at 760 mmHg
Molecular Weight 73.138
Flash Point ?20°F
Transport Information UN 1154 3/PG 2
Appearance Colorless liquid
Safety 16-26-29-36/37/39-45-3
Risk Codes 11-20/21/22-35
Molecular Structure
Hazard Symbols F,C
Synonyms Diethylamine(8CI);DEA;N,N-Diethylamine;
PSA 12.03000
LogP 1.00670

Synthetic route

: 27210-68-0
1-diethylamino-2,4-dinitronaphthalene

: 75-04-7
ethylamine

A: 27210-67-9
N-ethyl-2,4-dinitro-1-naphthylamine

B: 109-89-7
diethylamine

Conditions

Conditions	Yield
In water at 30℃; for 1h;	A 100% B n/a

...Expand

: 1066-87-1
(N,N-diethylamino)tributyltin

: 79109-72-1
2,5-diethynylthiophene

A: 166543-55-1
2,5-bis[(tributylstannyl)ethynyl]thiophene

B: 109-89-7
diethylamine

Conditions

Conditions	Yield
In neat (no solvent) stoich. amts., stirring (overnight, room temp., dry atmosphere), evapn. (vac.);	A 99% B n/a

...Expand

: 4519-35-1
phenylphosphonic acid bis(N,N-diethylamide)

: 104-94-9
4-methoxy-aniline

A: 70058-53-6
phenyl N,N'-bis(p-methoxyphenyl)phosphorodiamidite

B: 109-89-7
diethylamine

Conditions

Conditions	Yield
for 12h; Heating;	A 26.3% B 98.5%

...Expand

: 392-63-2
N,N'-diethyl-1,2,2,2-tetrafluoropropionamide

A: 109-89-7
diethylamine

B: 2,3,3,3-Tetrafluoropropanol-1

Conditions

Conditions	Yield
With aluminum (III) chloride; zinc borohydride In methanol at 60℃; for 10h; Reagent/catalyst; Temperature; Solvent;	A 95.7% B 98.1%

: 18279-61-3
trimethylsilyl diethylcarbamate

: 62305-44-6
trimethylsilyl <2-(trimethylsiloxy)ethyl>carbamate

A: 32284-58-5
N,N'-bis-<β-(trimethylsiloxy)>ethylcarbodiimide

B: 109-89-7
diethylamine

Conditions

Conditions	Yield
	A 66% B 98%

...Expand

: 104-94-9
4-methoxy-aniline

: 1636-14-2
bis(diethylamino)phenylphosphine

A: 70058-45-6
N,N'-bis(p-methoxyphenyl)-P-phenylphosphonous diamide

B: 109-89-7
diethylamine

Conditions

Conditions	Yield
for 14h; Heating;	A 83.7% B 98%
for 14h; Heating;	A 83.7% B 98%

...Expand

: 27210-68-0
1-diethylamino-2,4-dinitronaphthalene

: 74-89-5
methylamine

A: 39139-78-1
1-(Methylamino)-2,4-dinitronaphthalene

B: 109-89-7
diethylamine

Conditions

Conditions	Yield
In water at 30℃; for 1h;	A 97% B n/a

...Expand

: 620-92-8
bis-(4-hydroxyphenyl)methane

: 1636-14-2
bis(diethylamino)phenylphosphine

A: 4,4′-methylenedi(benzene-4,1-diyl) bis(N,N-diethyl-P-phenylphosphonamidite)

B: 109-89-7
diethylamine

Conditions

Conditions	Yield
In neat (no solvent) at 115 - 120℃; for 2h;	A 97% B n/a

...Expand

: 80-05-7
BPA

: 1636-14-2
bis(diethylamino)phenylphosphine

A: 146733-97-3
4,4′-(propane-2,2-diyl)di(benzene-4,1-diyl) bis(N,N-diethyl-P-phenylphosphonamidite)

B: 109-89-7
diethylamine

Conditions

Conditions	Yield
In neat (no solvent) at 115 - 120℃; for 2h;	A 97% B n/a

...Expand

: 69165-95-3
3-(trimethylsilyl)-1-(trimethylstannyl)propyne

: 1068-74-2
Diethylamino-trimethyl-stannan

A: 122691-55-8, 122691-53-6
3-(trimethylsilyl)-1,3-bis(trimethylstannyl)propyne

B: 122691-53-6
3-(trimethylsilyl)-1,1-bis(trimethylstannyl)propadiene

C: 122691-54-7
(Trimethylsilyl)tris(trimethylstannyl)propadiene

D: 109-89-7
diethylamine

Conditions

Conditions	Yield
In neat (no solvent) heating (180-200°C, 1 h), continuous removal of HNEt2; distn.; elem. anal.; mixt. of propadiene/propyne bis(trimethylastannyl)-derivatives (90:10 %) not separated;	A n/a B n/a C n/a D 96%

...Expand

: 64882-07-1
diethylammonium diethylcarbamate

: 109-89-7
diethylamine

Conditions

Conditions	Yield
In methanol at 60 - 65℃; for 2h;	95%

: 4519-35-1
phenylphosphonic acid bis(N,N-diethylamide)

: 62-53-3
aniline

A: 101-02-0
triphenyl phosphite

B: 15159-51-0
N,N',N''-triphenylphosphorous triamide

C: 26350-11-8
phenyl N,N'-diphenylphosphorodiamidite

D: 26350-10-7
diphenyl phenylphosphoramidite

E: 109-89-7
diethylamine

Conditions

Conditions	Yield
for 17h; Product distribution; Heating;	A n/a B n/a C n/a D n/a E 94.5%

...Expand

: 794-53-6
4-[(diethylamino)methyl]-2,6-bis(1,1-dimethylethyl)phenol

: 762-04-9
phosphonic acid diethyl ester

A: 976-56-7
diethyl 4-hydroxy-3,5-di-tert-butylbenzylphosphonate

B: 109-89-7
diethylamine

Conditions

Conditions	Yield
In toluene for 25h; Heating;	A 94% B n/a

...Expand

: 1636-14-2
bis(diethylamino)phenylphosphine

: 106-40-1
4-bromo-aniline

A: 70058-46-7
N,N'-bis(p-bromophenyl)-P-phenylphosphonous diamide

B: 109-89-7
diethylamine

Conditions

Conditions	Yield
for 18.5h; Heating;	A 68.1% B 93.6%

...Expand

: 615-21-4
1,3-benzothiazol-2-ylhydrazine

: 1636-14-2
bis(diethylamino)phenylphosphine

A: 131471-58-4
2-Hydrazono-3-(diethylaminophenylphosphino)-2,3-dihydro-1,3-benzothiazole

B: 109-89-7
diethylamine

Conditions

Conditions	Yield
at 110 - 115℃; under 5 - 10 Torr; for 1h;	A 92.3% B n/a

...Expand

: 1636-14-2
bis(diethylamino)phenylphosphine

: 62-53-3
aniline

A: 54459-40-4
N,N'-triphenylphosphonous diamide

B: 109-89-7
diethylamine

Conditions

Conditions	Yield
for 20h; Heating;	A 72.2% B 92.1%

...Expand

: 1636-14-2
bis(diethylamino)phenylphosphine

: 95-51-2
2-Chloroaniline

A: 70058-47-8
N,N'-bis(o-chlorophenyl)-P-phenylphosphonous diamide

B: 109-89-7
diethylamine

Conditions

Conditions	Yield
for 36h; Heating;	A 62.4% B 91.6%

...Expand

: 4519-35-1
phenylphosphonic acid bis(N,N-diethylamide)

: 106-40-1
4-bromo-aniline

A: 101-02-0
triphenyl phosphite

B: 109-89-7
diethylamine

C: diphenyl (p-bromophenyl)phosphoramidite

D: phenyl N,N'-bis(p-bromophenyl)phosphorodiamidite

E: N,N',N''-tris(p-bromophenyl)phosphorous triamide

Conditions

Conditions	Yield
for 22h; Product distribution; Heating;	A n/a B 91.4% C n/a D n/a E n/a

...Expand

: 123-42-2
4-Hydroxy-4-methyl-2-pentanone

A: 141-79-7
4-methyl-pent-3-en-2-one

B: 109-89-7
diethylamine

Conditions

Conditions	Yield
With hexaethylphosphoric triamide at 190℃; further reagent;	A 26.8% B 91.3%

: 2283-11-6
hexaethylphosphoric triamide

A: 141-79-7
4-methyl-pent-3-en-2-one

B: 109-89-7
diethylamine

Conditions

Conditions	Yield
With 4-Hydroxy-4-methyl-2-pentanone at 190℃;	A 26.8% B 91.3%

: 999-01-9
O,O'-diethyl thiophosphonate

: 794-53-6
4-[(diethylamino)methyl]-2,6-bis(1,1-dimethylethyl)phenol

A: 109-89-7
diethylamine

B: 3,5-di-tert-butyl-4-hydroxy-O,O-diethylbenzylphosphonate

Conditions

Conditions	Yield
In toluene for 25h; Heating;	A n/a B 90%

...Expand

: 107-21-1
ethylene glycol

: N,N-tetraethyldiamidothiophosphite S-propyl

A: 107-03-9
1-thiopropane

B: 3646-10-4, 54515-09-2, 673460-28-1
1,4,6,9-tetraoxa-5λ5-phosphaspiro[4,4]nonane

C: 109-89-7
diethylamine

Conditions

Conditions	Yield
at 120 - 130℃; for 1h;	A n/a B 90% C n/a
at 120 - 130℃; for 1h; Product distribution;	A n/a B 90% C n/a

...Expand

: 74895-71-9
1-Bicyclo[2.2.1]hept-5-en-2-yl-butane-1,2-dione

: 996-50-9
N,N-diethyl-1,1,1-trimethylsilanamine

A: 74895-77-5
(Z)-1-Bicyclo[2.2.1]hept-5-en-2-yl-2-trimethylsilanyloxy-but-2-en-1-one

B: 109-89-7
diethylamine

Conditions

Conditions	Yield
With toluene-4-sulfonic acid at 30 - 40℃; for 18h;	A 90% B n/a

...Expand

: 74895-74-2
1-(3-Methyl-bicyclo[2.2.1]hept-5-en-2-yl)-butane-1,2-dione

: 996-50-9
N,N-diethyl-1,1,1-trimethylsilanamine

A: 74895-80-0
(Z)-1-(3-Methyl-bicyclo[2.2.1]hept-5-en-2-yl)-2-trimethylsilanyloxy-but-2-en-1-one

B: 109-89-7
diethylamine

Conditions

Conditions	Yield
With toluene-4-sulfonic acid at 30 - 40℃; for 18h;	A 90% B n/a

...Expand

: 201230-82-2
carbon monoxide

: 6667-19-2
benzenenesulfenyl dimethylamine

A: 623-76-7
N,N'-diethylurea

B: 14288-05-2
N,N,N',N'-tetraethyloxamide

C: 109-89-7
diethylamine

D: diethylthiocarbamic acid S-phenyl ester

Conditions

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0) In pyridine at 80℃; under 14701.2 Torr; for 10h; Carbonylation;	A n/a B 1.4 % Spectr. C 3 % Spectr. D 90%

...Expand

: 20174-69-0
2-hydrazino-6-methylbenzothiazole

: 1636-14-2
bis(diethylamino)phenylphosphine

A: 131471-59-5
C18H23N4PS

B: 109-89-7
diethylamine

Conditions

Conditions	Yield
at 110 - 115℃; under 5 - 10 Torr; for 1h;	A 89.7% B n/a

...Expand

: 3710-84-7
N-ethyl-N-hydroxy-ethanamine

: 109-89-7
diethylamine

Conditions

Conditions	Yield
With carbon monoxide; hexarhodium hexadecacarbonyl In 2-ethoxy-ethanol; water at 40℃; under 12160 Torr; for 5h;	89%
With N,N,N'N'-tetramethyl-1,3-propanediamine; carbon monoxide; water; hexarhodium hexadecacarbonyl In 2-ethoxy-ethanol at 40℃; under 6080 Torr; for 5h;	93 % Chromat.
With N,N,N'N'-tetramethyl-1,3-propanediamine; carbon monoxide; water; hexarhodium hexadecacarbonyl In 2-ethoxy-ethanol at 40℃; under 6080 Torr; for 5h; Product distribution; Mechanism; (CH3)2NC3H6NH-substituted polystyrene instead of TMPDA; analogous reaction of other hydroxylamines;	93 % Chromat.

: 2078-71-9
(2-hydroxyethyl)urea

: 996-50-9
N,N-diethyl-1,1,1-trimethylsilanamine

A: 109-89-7
diethylamine

B: 75226-87-8
N-<2-(trimethylsiloxy)ethyl>-N'-(trimethylsilyl)urea

Conditions

Conditions	Yield
With ammonium sulfate at 120℃; for 1h;	A 82% B 89%

...Expand

: 1636-14-2
bis(diethylamino)phenylphosphine

: 51769-38-1
(4-chloro-1,3-benzothiazol-2-yl)hydrazine

A: 131471-60-8
C17H20ClN4PS

B: 109-89-7
diethylamine

Conditions

Conditions	Yield
at 110 - 115℃; under 5 - 10 Torr; for 1h;	A 88.5% B n/a

...Expand

: 109-79-5
1-butanethiol

: 52416-06-5
dibutyl diethylphosphoramidodithioite

A: 150-50-5
merphos

B: 109-89-7
diethylamine

Conditions

Conditions	Yield
for 0.5h; Ambient temperature;	A 88% B 77%

...Expand

: 1120-71-4
1,3-propanesultone

: 109-89-7
diethylamine

: 1116-85-4
3-(diethylamino)propane-1-sulfonic acid

Conditions

Conditions	Yield
In dichloromethane at 10℃; for 1h; Product distribution / selectivity;	100%
In dichloromethane Inert atmosphere;	53%

: 122-01-0
4-chloro-benzoyl chloride

: 109-89-7
diethylamine

: 7461-38-3
4-chloro-N,N-diethyl-benzamide

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0 - 20℃; for 6h;	100%
With sodium carbonate In tert-butyl methyl ether; water at 15 - 25℃; for 1h; Schotten-Baumann Reaction; Inert atmosphere;	98.7%
In toluene at 50℃;	90%

: 78-94-4
methyl vinyl ketone

: 109-89-7
diethylamine

: 3299-38-5
4-(diethylamino)butan-2-one

Conditions

Conditions	Yield
With copper diacetate In water at 20℃; for 12h; aza-Michael addition;	100%
copper diacetate In water at 20℃; for 15h; aza-type Michael addition;	100%
at 0℃; Inert atmosphere;	99%

: 7154-66-7
2-bromobenzoic acid chloride

: 109-89-7
diethylamine

: 76041-86-6
2-bromo-N,N-diethylbenzamide

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 20℃; for 0.5h; Inert atmosphere;	100%
In dichloromethane at 0 - 20℃; Schlenk technique;	99%
In dichloromethane at 0 - 20℃; for 0.5h;	95%

: 50-00-0
formaldehyd

: 103-90-2
4-acetaminophenol

: 109-89-7
diethylamine

: 121-78-8
N-{3-[(diethylamino)methyl]-4-hydroxyphenyl}acetamide

Conditions

Conditions	Yield
In ethanol at 80℃; for 1.5h; Microwave irradiation;	100%
In ethanol for 12h; Heating;	80%
In ethanol at 80℃; for 1h; Microwave irradiation;	77%

...Expand

: 764-85-2
Nonanoyl chloride

: 109-89-7
diethylamine

: 10385-09-8
N,N-diethyl nonanamide

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 20℃; for 14h; Inert atmosphere;	100%
With triethylamine In dichloromethane at 0 - 20℃; for 14h; Inert atmosphere;	100%
With diethyl ether; triethylamine
With benzene

: 627-63-4
fumaryl dichloride

: 109-89-7
diethylamine

: 111328-65-5, 138895-86-0, 37511-04-9
N1,N1,N4,N4-tetraethylfumaramide

Conditions

Conditions	Yield
In diethyl ether at 0 - 20℃; Inert atmosphere;	100%
With diethyl ether

: 109-89-7
diethylamine

: 107-13-1
acrylonitrile

: 5351-04-2
3-diethylaminopropionitrile

Conditions

Conditions	Yield
With copper diacetate In water at 20℃; for 12h; aza-Michael addition;	100%
iron(III) chloride In water at 20℃; for 15h; aza-type Michael addition;	100%
1-butyl-3-methylimidazolium Tetrafluoroborate In water at 20℃; for 7h; aza-Michael reaction;	97%

: 109-89-7
diethylamine

: 141-75-3
butyryl chloride

: 1114-76-7
N,N-diethyl-butyramide

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0 - 20℃;	100%
With benzene
With diethyl ether
In benzene
With sodium carbonate In benzene at 0 - 5℃;

: 109-89-7
diethylamine

: 79-04-9
chloroacetyl chloride

: 2315-36-8
2-Chloro-N,N-diethylacetamide

Conditions

Conditions	Yield
In dichloromethane; water at 5℃; Temperature; Solvent;	100%
With triethylamine In dichloromethane at 0℃;	99%
With triethylamine In 1,2-dichloro-ethane at 10 - 20℃; for 3h; Cooling with ice;	95%

: 50-00-0
formaldehyd

: 109-89-7
diethylamine

: 536-74-3
phenylacetylene

: 22396-72-1
diethyl-(3-phenyl-prop-2-ynyl)-amine

Conditions

Conditions	Yield
With copper dichloride at 80℃; under 150.015 Torr; for 3h; Mannich reaction;	100%
With silver nitrate at 105℃; for 0.133333h; microwave irradiation;	99%
copper(l) iodide In water; dimethyl sulfoxide at 30℃; for 10h;	98%

...Expand

: 109-89-7
diethylamine

: 97-00-7
1-chloro-2,4-dinitro-benzene

: 837-64-9
N,N-diethyl-2,4-dinitroaniline

Conditions

Conditions	Yield
In ethanol; water at 60℃; for 6h;	100%
In acetonitrile at 25℃; for 2h; Solvent;	85%
With ethanol
With sodium carbonate In acetone for 5h; Substitution; Heating;
In acetonitrile at 25℃; Kinetics; Solvent;

: 109-89-7
diethylamine

: 645-45-4
hydrocinnamic acid chloride

: 18859-19-3
N,N-diethyl-3-phenylpropanamide

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 20℃; for 14h; Inert atmosphere;	100%
With triethylamine In dichloromethane at 0 - 20℃; for 14h; Inert atmosphere;	96%

: 109-89-7
diethylamine

: 140-88-5
ethyl acrylate

: 5515-83-3
ethyl 3-(diethylamino)propionate

Conditions

Conditions	Yield
With copper diacetate In water at 20℃; for 12h; aza-Michael addition;	100%
iron(III) chloride In dichloromethane at 25℃; for 42h; Product distribution; various catalysts and further amines with various Michael acceptors;	96%
iron(III) chloride In dichloromethane at 25℃; for 42h;	96%

: 109-89-7
diethylamine

: 1069-08-5
diethylphosphoramidous dichloride

Conditions

Conditions	Yield
With phosphorus trichloride In diethyl ether at -78 - 20℃; for 2h;	100%
With phosphorus trichloride In diethyl ether at -78 - 20℃; Inert atmosphere;	100%
With phosphorus trichloride In diethyl ether at -78 - 20℃; for 2h;	100%

: 109-89-7
diethylamine

: 55-18-5
N-Nitrosodiethylamine

Conditions

Conditions	Yield
With [NO(1+)18-crown-6H(NO3)2(1-)] In dichloromethane at 20℃; for 0.0833333h;	100%
With magnesium hydrogen sulfate; silica gel; sodium nitrite In dichloromethane at 20℃; for 1h; Nitrosation;	98%
With aluminium trichloride; silica gel; sodium nitrite In dichloromethane at 20℃; for 0.5h; Nitrosation;	98%

: 674-82-8
4-methyleneoxetan-2-one

: 109-89-7
diethylamine

: 2235-46-3
N,N-diethyl-3-oxobutanamide

Conditions

Conditions	Yield
In tetrahydrofuran at 0℃; Inert atmosphere;	100%
In tetrahydrofuran at 0℃; for 0.0833333h; Inert atmosphere;	100%
With triethylamine In methanol; toluene at 0℃; for 2h;	95%

: 109-89-7
diethylamine

: 762-42-5
dimethyl acetylenedicarboxylate

: 996-85-0
dimethyl (2E)-2-(diethylamino)but-2-enedioate

Conditions

Conditions	Yield
In water at 20℃; for 2h; Michael-type addition;	100%
In diethyl ether

: 96-48-0
4-butanolide

: 109-89-7
diethylamine

: 86452-59-7
N,N-Diethyl-4-hydroxy-butyramide

Conditions

Conditions	Yield
In acetonitrile at 30℃; under 6750540 Torr; for 96h;	100%
Stage #1: diethylamine With diisobutylaluminium hydride In tetrahydrofuran; toluene Stage #2: 4-butanolide In tetrahydrofuran at 45℃; for 2h;	72%

: 201230-82-2
carbon monoxide

: 100-39-0
benzyl bromide

: 109-89-7
diethylamine

: 30085-50-8
S-benzyl N,N-diethylthiolcarbamate

Conditions

Conditions	Yield
With sulfur; selenium In tetrahydrofuran 1.) 30 deg C; 2.) rt.;	100%
With n-butyllithium; sulfur 1.) THF/hexane, from -78 deg C to -20 deg C; 2.) - 78 deg C; 3.) 20 deg C, 1 atm, 2 h; Yield given. Multistep reaction;
Yield given. Multistep reaction;

...Expand

: 54632-27-8
7-chloro-1,3-dimethyl-6-azalumazine

: 109-89-7
diethylamine

: 111934-38-4
7-(diethylamino)-1,3-dimethyl-6-azalumazine

Conditions

Conditions	Yield
In dichloromethane for 2.5h;	100%

: 50-00-0
formaldehyd

: 13780-89-7
N-(3-sec-Butyl-4-hydroxy-phenyl)-acetamide

: 109-89-7
diethylamine

: 107244-66-6
N-(3-sec-Butyl-5-diethylaminomethyl-4-hydroxy-phenyl)-acetamide

Conditions

Conditions	Yield
In ethanol for 48h; Heating;	100%

...Expand

: 50-00-0
formaldehyd

: 101712-35-0
N-(6-Hydroxy-2',5'-dimethoxy-biphenyl-3-yl)-acetamide

: 109-89-7
diethylamine

: 101712-53-2
N-(5-Diethylaminomethyl-6-hydroxy-2',5'-dimethoxy-biphenyl-3-yl)-acetamide

Conditions

Conditions	Yield
In ethanol; water Heating;	100%

...Expand

: 50-00-0
formaldehyd

: 79290-53-2
N-(6-Hydroxy-2'-trifluoromethyl-biphenyl-3-yl)-acetamide

: 109-89-7
diethylamine

: 79290-47-4
N-(5-Diethylaminomethyl-6-hydroxy-2'-trifluoromethyl-biphenyl-3-yl)-acetamide

Conditions

Conditions	Yield
In ethanol; water Heating;	100%

...Expand

: 50-00-0
formaldehyd

: 10403-51-7
3a,3b,4,4a,7a,8,8b-octahydro-4,8-ethenopyrrolo<3',4':3,4>cyclobut<1,2-f>isoindole-1,3,5,7<2H,6H>tetrone

: 109-89-7
diethylamine

: 96488-35-6
C24H34N4O4

Conditions

Conditions	Yield
In water; N,N-dimethyl-formamide at 70℃; for 6h;	100%

...Expand

: 2274-11-5
ethylene glycol diacrylate

: 109-89-7
diethylamine

: 81166-07-6
1,10-bis-diethylamino-4,7-dioxa-3,8-dioxodecane

Conditions

Conditions	Yield
In diethyl ether for 18h; Ambient temperature;	100%

: 22606-71-9
Diethylamino-(chlormethyl)-chlorphosphin

: 109-89-7
diethylamine

: 100548-25-2
P-(Chloromethyl)-N,N,N',N'-tetraethylphosphonous diamide

Conditions

Conditions	Yield
In diethyl ether	100%

: 7468-67-9
o-formylbenzonitrile

: 109-89-7
diethylamine

: 93679-82-4
3-Diethylamino-2,3-dihydro-isoindol-1-one

Conditions

Conditions	Yield
at 40℃; for 1h;	100%

: 59938-06-6
(E)-4-Ethoxy-1,1,1-trifluoro-3-buten-2-one

: 109-89-7
diethylamine

: 34648-03-8
β-(N,N-diethylamino)vinyltrifluoromethylketone

Conditions

Conditions	Yield
In acetonitrile Ambient temperature;	100%
In cyclohexane at 19.9℃; Rate constant; other solvents; ΔG(excit.), ΔH(excit.), ΔS(excit.);
In cyclohexane at 19.9℃; Yield given;

: 87064-07-1
4-bromo-4-methyl-1-phenyl-pent-1-yn-3-one

: 109-89-7
diethylamine

: 87064-08-2
(Z)-4-Bromo-1-diethylamino-4-methyl-1-phenyl-pent-1-en-3-one

Conditions

Conditions	Yield
In hexane Ambient temperature;	100%

Diethylamine Specification

The Diethylamine, with the cas register number 109-89-7, has other synonyms, such as (c2h5)2nh; ai3-24215; detn; diaethylamin; diethamine; diethylamin; dietilamina; dwuetyloamina.

The characteristics of this chemical could be summarized as: (1)ACD/LogP: 0.63; (2)ACD/LogD (pH 5.5): -2.46; (3)ACD/LogD (pH 7.4): -2.28; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 1; (7)ACD/KOC (pH 7.4): 1; (8)#H bond acceptors: 1; (9)#H bond donors: 1; (10)#Freely Rotating Bonds: 2; (11)Polar Surface Area: 3.24; (12)Index of Refraction: 1.384 ; (13)Molar Refractivity: 24.17 cm³; (14)Molar Volume: 103.3 cm³; (15)Polarizability: 9.58 ×10^-24 cm³; (16)Surface Tension: 20.2 dyne/cm; (17)Density: 0.707 g/cm³; (18)Enthalpy of Vaporization: 29.06 kJ/mol; (19)Boiling Point: 57.3 °C at 760 mmHg; (20)Vapour Pressure: 218 mmHg at 25°C.

This is a kind of colorless combustible liquid with strong smell of ammonia, and it is complete soluble in water, ethanol and ethyl ether. And it is sensitive to air and incompatible with strong oxidizing agents, so while keeping, you should keep it under argon in the room temperature.

Being a kind of highly flammable chemical, it may catch fire in contact with air, only needing brief contact with an ignition source, and it has a very low flash point or evolve highly flammable gases in contact with water. Besides, it is corrosive, and it may destroy living tissue on contact. Then it is harmful by inhalation, in contact with skin or if swallowed and it could cause severe burns.

While using this chemical, you should take the following instructions to protece yourself. Keep away from sources of ignition - No smoking and keep in a cool place. Wear suitable protective clothing, gloves and eye/face protection, and if in case of contact with eyes, rinse immediately with plenty of water and seek medical advice; if in case of accident or if you feel unwell seek medical advice immediately (show the label where possible). Lastly, do not empty into drains. You could also refer to WGK Germany 1 to get more safety information.

Diethylamine could be applied in many ways, such as being the analytical reagent and preservative and also be used in making organic synthesis and dyeing. Besides, it could also be as the intermediates, such as for pesticide, such as phosphamidon and pyrimithate, and for herbicide, such as benthiocarb and napropamide. What's more, it could be the solvent and chemical material intermediate to make the medicine, such as procaine, chloroquine, nikethamide, Coraminum and sulfanilamide, and other different fields, such as thiofide, beneficiation reagent, textile assistant, fungicide, corrosion inhibitor, polymerization inhibitor, antifreeze agent and so on.

As to its product categories, there are various, including pharmaceutical intermediates; intermediates of dyes and pigments; chemical synthesis; organic bases; synthetic reagents; essential chemicals; reagent plus; routine reagents; analytical reagents for general use; c-d, puriss p.a.; puriss p.a. And its preparation products are numerous, containing 4-phenyl-1-(p-tolylsulphonyl)piperidine-4-carboxylic acid , montelukast, 4'-iodoacetophenone, 4,6-dimethyl-1h-pyrazolo[3,4-b]pyridin-3-amine, 2-amino-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carbonitrile, 2-amino-5,6-dihydro-4h-cyclopenta[b]thiophene-3-carbonitrile, 1,4,6-trimethyl-1h-pyrazolo[3,4-b]pyridin-3-ylamine ,97%, 7-(diethylamino)-5-methyl-s-triazolo[1,5-a]pyrimidine, diethylcarbamyl chloride, benzyl cinnamate, 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carbonitrile, 2-amino-4,5-dimethyl-thiophene-3-carbonitrile, 3-(diethylamino)propanoic acid, benzyl salicylate, 5-amino-3-methyl-thiophene-2,4-dicarboxylic acid dimethyl ester, (5-bromo-pyrimidin-2-yl)-diethyl-amine, while its raw material are the etanol, ammonia, hydrogen, 2-ethylaniline, and 2-(ethylamino)ethanol.

Additionally, you could convert the following data information into the molecular structure:
SMILES:N(CC)CC
InChI:InChI=1/C4H11N/c1-3-5-4-2/h5H,3-4H2,1-2H3
InChIKey:HPNMFZURTQLUMO-UHFFFAOYAD

Below are the toxicity information of this chemical:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mammal (species unspecified)	LC50	inhalation	5000mg/m3 (5000mg/m3)		Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 14, Pg. 80, 1975.
mouse	LCLo	inhalation	3gm/m3/2H (3000mg/m3)	BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA LIVER: FATTY LIVER DEGERATION	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 20(4), Pg. 28, 1955.
mouse	LD50	intraperitoneal	585mg/kg (585mg/kg)		Yakugaku Zasshi. Journal of Pharmacy. Vol. 97, Pg. 1117, 1977.
mouse	LD50	oral	500mg/kg (500mg/kg)	BEHAVIORAL: SLEEP BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Biomedica Biochimica Acta. Vol. 44, Pg. 795, 1985.
rabbit	LCLo	inhalation	20gm/m3 (20000mg/m3)	SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION LUNGS, THORAX, OR RESPIRATION: EMPHYSEMA LIVER: FATTY LIVER DEGERATION	"Voprosy Promyshlennoi Toksikologii," Pravdin, N.S., ed., Akademiya Meditsinskikh Nauk-SSSR, Moscos, Russia, 1960Vol. -, Pg. 176, 1960.
rabbit	LD50	skin	820uL/kg (0.82mL/kg)		AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951.
rat	LC50	inhalation	4000ppm/4H (4000ppm)		Archives of Environmental Health. Vol. 1, Pg. 343, 1960.
rat	LD50	oral	540mg/kg (540mg/kg)		Archives of Environmental Health. Vol. 1, Pg. 343, 1960.
rat	LDLo	intraperitoneal	50mg/kg (50mg/kg)		Farmakologiya i Toksikologiya Vol. 31, Pg. 238, 1968.

Product Name

Diethylamine

Synthetic route

Diethylamine Specification

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