Product Name

  • Name

    Dipropylamine

  • EINECS 205-565-9
  • CAS No. 142-84-7
  • Article Data114
  • CAS DataBase
  • Density 0.741 g/cm3
  • Solubility soluble in water
  • Melting Point -63 °C
  • Formula C6H15N
  • Boiling Point 108.8 °C at 760 mmHg
  • Molecular Weight 101.192
  • Flash Point 3.9 °C
  • Transport Information UN 2383 3/PG 2
  • Appearance clear, colorless liquid
  • Safety 16-26-36/37/39-45
  • Risk Codes 11-20/21/22-35
  • Molecular Structure Molecular Structure of 142-84-7 (Dipropylamine)
  • Hazard Symbols FlammableF,CorrosiveC
  • Synonyms Dipropylamine(8CI);Di-n-propylamine;Dipropanamine;N,N-Dipropylamine;N-Propyl-1-propanamine;n-Dipropylamine;
  • PSA 12.03000
  • LogP 1.78690

Synthetic route

benzyl diallylcarbamate
25070-76-2

benzyl diallylcarbamate

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In tetrahydrofuran-d8 at 20℃; for 24h;100%
With hydrogen In d(4)-methanol at 20℃; under 760.051 Torr; for 24h;100%
With hydrogen In methanol; d(4)-methanol at 40℃; under 760.051 Torr; for 1h; Reagent/catalyst; chemoselective reaction;100%
With hydrogen In d(4)-methanol at 20℃; under 2280.15 Torr; for 24h; Reagent/catalyst; chemoselective reaction;
propylamine
107-10-8

propylamine

ethene
74-85-1

ethene

carbon monoxide
201230-82-2

carbon monoxide

A

tri-n-propylamine
102-69-2

tri-n-propylamine

B

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
di(rhodium)tetracarbonyl dichloride In ethanol at 119℃; under 44253.5 Torr; for 1h;A 1%
B 99%
di(rhodium)tetracarbonyl dichloride In ethanol at 119℃; under 44253.5 Torr; for 1h;A 2%
B 98%
C10H19NO2

C10H19NO2

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With titanium(IV) isopropylate; chloro-trimethyl-silane; magnesium In tetrahydrofuran at 50℃; for 24h;94%
propiononitrile
107-12-0

propiononitrile

A

tri-n-propylamine
102-69-2

tri-n-propylamine

B

N-propylidenepropylamine
7707-70-2

N-propylidenepropylamine

C

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With hydrogen at 220℃;A 8.5%
B 2.5%
C 89%
With hydrogen at 240℃; Temperature; Flow reactor;A 13%
B 2.5%
C 80%
3-Dipropylamino-7-hydroxy-heptanenitrile
64935-06-4

3-Dipropylamino-7-hydroxy-heptanenitrile

A

(+/-)-2-perhydro-2H-pyran-2-ylethanenitrile
75394-84-2

(+/-)-2-perhydro-2H-pyran-2-ylethanenitrile

B

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With potassium tert-butylate at 180℃;A 88%
B 61%
N-nitroso-N,N-dipropylamine
621-64-7

N-nitroso-N,N-dipropylamine

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With isocyanate de chlorosulfonyle In diethyl ether for 10h; Ambient temperature;69%
1-dipropylamino-4-methyl-3-penten-1-ynamine
75162-84-4

1-dipropylamino-4-methyl-3-penten-1-ynamine

ethylenediamine
107-15-3

ethylenediamine

A

di-n-propylamine
142-84-7

di-n-propylamine

B

2-(3-methyl-2-butenyl)imidazoline
87703-38-6

2-(3-methyl-2-butenyl)imidazoline

Conditions
ConditionsYield
With sulfuric acid In 1,4-dioxaneA n/a
B 68%
1-dipropylamino-4-methyl-3-penten-1-ynamine
75162-84-4

1-dipropylamino-4-methyl-3-penten-1-ynamine

ethanolamine
141-43-5

ethanolamine

A

2-(3-methyl-2-butenyl)oxazoline
87703-36-4

2-(3-methyl-2-butenyl)oxazoline

B

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With sulfuric acid In 1,4-dioxane at 100℃; for 4h;A 65%
B n/a
1-dipropylamino-3-penten-1-yne
70490-69-6

1-dipropylamino-3-penten-1-yne

ethylenediamine
107-15-3

ethylenediamine

A

di-n-propylamine
142-84-7

di-n-propylamine

B

2-(2-butenyl)imidazoline
87703-37-5

2-(2-butenyl)imidazoline

Conditions
ConditionsYield
With sulfuric acid In 1,4-dioxaneA n/a
B 60%
N-propylidenepropylamine
7707-70-2

N-propylidenepropylamine

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With ethanol; calcium at 20℃; for 24h;55%
1-dipropylamino-3-penten-1-yne
70490-69-6

1-dipropylamino-3-penten-1-yne

ethanolamine
141-43-5

ethanolamine

A

2-(2-butenyl)oxazoline
87703-35-3

2-(2-butenyl)oxazoline

B

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With sulfuric acid In 1,4-dioxane at 100℃; for 4h;A 52%
B n/a
Tris(di-n-propylamino)phosphine
5848-64-6

Tris(di-n-propylamino)phosphine

C14H11ClN4OS
131471-75-5

C14H11ClN4OS

A

N-phenyl-N',N'-di(n-propyl)urea
15545-56-9

N-phenyl-N',N'-di(n-propyl)urea

B

C25H45ClN6P2S
131471-73-3

C25H45ClN6P2S

C

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
at 125℃; under 130 Torr;A n/a
B 11.5%
C n/a
Tris(di-n-propylamino)phosphine
5848-64-6

Tris(di-n-propylamino)phosphine

1-(6-Methyl-2-benzothiazolyl)-4-phenylsemicarbazide
131471-74-4

1-(6-Methyl-2-benzothiazolyl)-4-phenylsemicarbazide

A

N-phenyl-N',N'-di(n-propyl)urea
15545-56-9

N-phenyl-N',N'-di(n-propyl)urea

B

C26H48N6P2S
131471-70-0

C26H48N6P2S

C

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
at 125℃; under 130 Torr;A n/a
B 11%
C n/a
propan-1-ol
71-23-8

propan-1-ol

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With ammonia at 420℃; ueber Silicagel;
propylamine
107-10-8

propylamine

tri-n-propylamine
102-69-2

tri-n-propylamine

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With alumina hydrate; ammonia at 370℃; under 139746 Torr;
O-Methylhydroxylamin
67-62-9

O-Methylhydroxylamin

n-propylmagnesium bromide
927-77-5

n-propylmagnesium bromide

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With diethyl ether at -10℃; zuletzt bei Siedetemperatur;
1-Chloropropane
540-54-5

1-Chloropropane

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With ethanol; ammonia; water at 100℃; under 5148.6 - 7355.08 Torr;
With ethanol; ammonia; water at 100℃; under 5148.6 - 7355.08 Torr;
dipropylamine-N-carbonitrile
1531-36-8

dipropylamine-N-carbonitrile

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With sulfuric acid; hydrogen
di-n-propyl zinc
628-91-1

di-n-propyl zinc

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With chloroamine; Petroleum ether at -30℃;
propyl bromide
106-94-5

propyl bromide

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With ethanol; ammonia; water at 100℃; under 5148.6 - 7355.08 Torr;
With ethanol; ammonia; water at 100℃; under 5148.6 - 7355.08 Torr;
N,N-diisopropyl-N'-propyl-urea
447429-10-9

N,N-diisopropyl-N'-propyl-urea

ethylene glycol
107-21-1

ethylene glycol

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
at 100℃; Rate constant;
propylamine
107-10-8

propylamine

propionaldehyde
123-38-6

propionaldehyde

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With nickel at 162 - 195℃; under 36775.4 - 73550.8 Torr; Hydrogenation;
propionaldehyde
123-38-6

propionaldehyde

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With methanol; ammonia; nickel at 155 - 165℃; under 51485.6 Torr; Hydrogenation;
1-Nitropropane
108-03-2

1-Nitropropane

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With ethanol; nickel at 40 - 50℃; under 4413.05 - 80905.8 Torr; Hydrogenation;
With hydrogenchloride; iron at 100℃;
With nickel-cobalt-cadmium-chromium at 390 - 400℃;
With ethanol; nickel at 100℃; under 102971 Torr; Hydrogenation;
acrolein
107-02-8

acrolein

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With Ni-doped silica; ammonia; hydrogen at 125℃;
With Ni-doped silica; ammonia; hydrogen at 125℃;
propiononitrile
107-12-0

propiononitrile

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With ammonia; nickel at 100 - 150℃; under 73550.8 Torr; Hydrogenation;
With hydrogenchloride; platinum under 2206.5 Torr; Hydrogenation;
With 5%-palladium/activated carbon; ammonium formate In ethanol at 20℃;
propiononitrile
107-12-0

propiononitrile

A

propylamine
107-10-8

propylamine

B

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
With hydrogen; nickel boride; silica gel In ethanol at 70℃; under 4560 Torr; Product distribution; Kinetics; other nickel catalyst, different times, solvents, and temp.;
With hydrogen; nickel In methanol at 70℃; under 7500.6 Torr; Product distribution; also in presence of amines, competition with cyclohexene;
With nickel at 130 - 140℃; Hydrogenation.unter Normaldruck;
With ethanol; ammonia; nickel at 125℃; under 44130.5 Torr; Hydrogenation;
N,N-diisopropyl-N'-propyl-urea
447429-10-9

N,N-diisopropyl-N'-propyl-urea

benzyl alcohol
100-51-6

benzyl alcohol

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
at 100℃; Rate constant;
diethyl ether
60-29-7

diethyl ether

N,N-Dipropyl-chloramine
5775-34-8

N,N-Dipropyl-chloramine

benzylmagnesium chloride
6921-34-2

benzylmagnesium chloride

A

N-benzyl-N,N-dipropylamine
20441-12-7

N-benzyl-N,N-dipropylamine

B

di-n-propylamine
142-84-7

di-n-propylamine

Conditions
ConditionsYield
at 5℃;
di-n-propylamine
142-84-7

di-n-propylamine

N-nitroso-N,N-dipropylamine
621-64-7

N-nitroso-N,N-dipropylamine

Conditions
ConditionsYield
With toluene-4-sulfonic acid; sodium nitrite In dichloromethane at 20℃;100%
With dinitrogen trioxide Kinetics; Rate constant; Thermodynamic data; ΔH(excit.);
With hydrogenchloride; sodium nitrite
ethene
74-85-1

ethene

carbon monoxide
201230-82-2

carbon monoxide

di-n-propylamine
142-84-7

di-n-propylamine

tri-n-propylamine
102-69-2

tri-n-propylamine

Conditions
ConditionsYield
di(rhodium)tetracarbonyl dichloride In ethanol at 115℃; under 37503 Torr; for 1.5h;100%
di-n-propylamine
142-84-7

di-n-propylamine

Toluene-4-sulfonic acid 1-(toluene-4-sulfonyl)-piperidin-2-ylmethyl ester
63587-45-1

Toluene-4-sulfonic acid 1-(toluene-4-sulfonyl)-piperidin-2-ylmethyl ester

Dipropyl-[1-(toluene-4-sulfonyl)-piperidin-2-ylmethyl]-amine
186790-30-7

Dipropyl-[1-(toluene-4-sulfonyl)-piperidin-2-ylmethyl]-amine

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene for 48h; Heating;100%
indole-2,3-dione
91-56-5

indole-2,3-dione

di-n-propylamine
142-84-7

di-n-propylamine

(2-Amino-phenyl)-oxo-acetic acid; compound with dipropyl-amine

(2-Amino-phenyl)-oxo-acetic acid; compound with dipropyl-amine

Conditions
ConditionsYield
In water Heating;100%
di-n-propylamine
142-84-7

di-n-propylamine

4-[phenyl(exo-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)amino]benzoic acid

4-[phenyl(exo-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)amino]benzoic acid

N,N-di-n-propyl-4-[phenyl(exo-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)amino]benzamide
347888-67-9

N,N-di-n-propyl-4-[phenyl(exo-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)amino]benzamide

Conditions
ConditionsYield
With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate Acylation;100%
di-n-propylamine
142-84-7

di-n-propylamine

4-[phenyl(endo-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)amino]benzoic acid
287721-05-5

4-[phenyl(endo-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)amino]benzoic acid

4-[(8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-phenyl-amino]-N,N-dipropyl-benzamide
287720-98-3

4-[(8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-phenyl-amino]-N,N-dipropyl-benzamide

Conditions
ConditionsYield
With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate Acylation;100%
3-(triethoxypropyl) isocyanate
24801-88-5

3-(triethoxypropyl) isocyanate

di-n-propylamine
142-84-7

di-n-propylamine

N-di-n-propyl-N'-[3-(triethoxysilyl)propyl]urea

N-di-n-propyl-N'-[3-(triethoxysilyl)propyl]urea

Conditions
ConditionsYield
In hexane at 20℃; for 3h;100%
6-(2-hydroxyethyl)-2-(methylthio)-4-pyrimidinyl 4-methyl-1-benzenesulfonate
920490-05-7

6-(2-hydroxyethyl)-2-(methylthio)-4-pyrimidinyl 4-methyl-1-benzenesulfonate

di-n-propylamine
142-84-7

di-n-propylamine

C13H23N3OS

C13H23N3OS

Conditions
ConditionsYield
In tetrahydrofuran at 70℃; for 48h;100%
5-nitro-1,3-benzenedicarboxylic acid, monomethyl ester
1955-46-0

5-nitro-1,3-benzenedicarboxylic acid, monomethyl ester

di-n-propylamine
142-84-7

di-n-propylamine

5-nitro-N,N-dipropyl-isophthalamic acid methyl ester
328284-59-9

5-nitro-N,N-dipropyl-isophthalamic acid methyl ester

Conditions
ConditionsYield
Stage #1: 5-nitro-1,3-benzenedicarboxylic acid, monomethyl ester With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 20℃; for 1h;
Stage #2: di-n-propylamine In dichloromethane at 20℃; for 0.5h;
100%
With 1,1'-carbonyldiimidazole In dichloromethane at 20℃; for 5h;75%
2-hydroxy-2-(4-methoxybenzoyl)cyclohexane-1-carboxylic acid
1071600-29-7

2-hydroxy-2-(4-methoxybenzoyl)cyclohexane-1-carboxylic acid

di-n-propylamine
142-84-7

di-n-propylamine

2-hydroxy-2-(4-methoxy-benzoyl)-cyclohexanecarboxylate dipropyl-ammonium
1071600-59-3

2-hydroxy-2-(4-methoxy-benzoyl)-cyclohexanecarboxylate dipropyl-ammonium

Conditions
ConditionsYield
In toluene at 65℃; Heating / reflux;100%
tert-butyl (4-{[(6-chloropyrimidin-4-yl)carbonyl]amino}benzyl)carbamate
1114592-18-5

tert-butyl (4-{[(6-chloropyrimidin-4-yl)carbonyl]amino}benzyl)carbamate

di-n-propylamine
142-84-7

di-n-propylamine

tert-butyl [4-({[6-(dipropylamino)pyrimidin-4-yl]carbonyl}amino)benzyl]carbamate

tert-butyl [4-({[6-(dipropylamino)pyrimidin-4-yl]carbonyl}amino)benzyl]carbamate

Conditions
ConditionsYield
With triethylamine In ethanol at 100℃; for 2.5h; microwave irradiation; sealed tube;100%
5,7-dichloro-6-methoxypyrazolo[1,5-a]pyrimidine
1338931-99-9

5,7-dichloro-6-methoxypyrazolo[1,5-a]pyrimidine

di-n-propylamine
142-84-7

di-n-propylamine

(5-chloro-6-methoxypyrazolo[1,5-a]pyrimidin-7-yl)dipropylamine
1338932-08-3

(5-chloro-6-methoxypyrazolo[1,5-a]pyrimidin-7-yl)dipropylamine

Conditions
ConditionsYield
In tetrahydrofuran at 0 - 20℃; chemoselective reaction;100%
di-n-propylamine
142-84-7

di-n-propylamine

Diethyl vinylphosphonate
682-30-4

Diethyl vinylphosphonate

C12H28NO3P
1415210-87-5

C12H28NO3P

Conditions
ConditionsYield
With water at 100℃; for 0.0833333h; Inert atmosphere;100%
naphtho[2,3-d][1,3]dioxole-6-carboxylic acid

naphtho[2,3-d][1,3]dioxole-6-carboxylic acid

di-n-propylamine
142-84-7

di-n-propylamine

N,N-dipropylnaphtho[2,3-d][1,3]dioxole-6-carboxamide
1616610-11-7

N,N-dipropylnaphtho[2,3-d][1,3]dioxole-6-carboxamide

Conditions
ConditionsYield
Stage #1: naphtho[2,3-d][1,3]dioxole-6-carboxylic acid With oxalyl dichloride In dichloromethane; N,N-dimethyl-formamide at 0 - 20℃; Inert atmosphere;
Stage #2: di-n-propylamine In dichloromethane; N,N-dimethyl-formamide at 0 - 20℃;
100%
tert-butyl 2-hydroxy-4-(2-oxoethyl)-2,3-dihydro-1H-indole-1-carboxylate

tert-butyl 2-hydroxy-4-(2-oxoethyl)-2,3-dihydro-1H-indole-1-carboxylate

di-n-propylamine
142-84-7

di-n-propylamine

tert-butyl 4-(2-(dipropylamino)ethyl)-2-hydroxyindoline-1-carboxylate

tert-butyl 4-(2-(dipropylamino)ethyl)-2-hydroxyindoline-1-carboxylate

Conditions
ConditionsYield
Stage #1: tert-butyl 2-hydroxy-4-(2-oxoethyl)-2,3-dihydro-1H-indole-1-carboxylate; di-n-propylamine With acetic acid In dichloromethane for 0.75h;
Stage #2: With sodium cyanoborohydride In dichloromethane for 2h;
100%
(S)-(-)-1,1-dimethylethyl <3-methyl-1-<<(methylsulfonyl)oxy>methyl>butyl>carbamate
109687-65-2

(S)-(-)-1,1-dimethylethyl <3-methyl-1-<<(methylsulfonyl)oxy>methyl>butyl>carbamate

di-n-propylamine
142-84-7

di-n-propylamine

(S)-tert-butyl 1-(dipropylamino)-4-methylpentan-2-ylcarbamate

(S)-tert-butyl 1-(dipropylamino)-4-methylpentan-2-ylcarbamate

Conditions
ConditionsYield
With triethylamine In acetonitrile at 20℃; for 40h; Inert atmosphere;100%
(2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate
126301-19-7, 134807-64-0, 109687-66-3

(2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate

di-n-propylamine
142-84-7

di-n-propylamine

(S)-tert-butyl 1-(dipropylamino)-3-phenylpropan-2-ylcarbamate

(S)-tert-butyl 1-(dipropylamino)-3-phenylpropan-2-ylcarbamate

Conditions
ConditionsYield
With triethylamine In acetonitrile at 20℃; for 40h; Inert atmosphere;100%
(2S)-2-[(tert-butoxycarbonyl)amino]propyl methanesulfonate
126301-16-4

(2S)-2-[(tert-butoxycarbonyl)amino]propyl methanesulfonate

di-n-propylamine
142-84-7

di-n-propylamine

(S)-tert-butyl 1-(dipropylamino)propan-2-ylcarbamate

(S)-tert-butyl 1-(dipropylamino)propan-2-ylcarbamate

Conditions
ConditionsYield
With triethylamine In acetonitrile at 20℃; for 40h; Inert atmosphere;100%
di-n-propylamine
142-84-7

di-n-propylamine

N,N-dipropylamine hydrochloride
5326-84-1

N,N-dipropylamine hydrochloride

Conditions
ConditionsYield
With hydroxylamine hydrochloride In ethanol for 2h; Reflux;100%
(Z)-9-octadecenoyl chloride
112-77-6

(Z)-9-octadecenoyl chloride

di-n-propylamine
142-84-7

di-n-propylamine

N,N-dipropyloleamide
13653-24-2

N,N-dipropyloleamide

Conditions
ConditionsYield
In benzene for 1h; Ambient temperature;99.5%
di-n-propylamine
142-84-7

di-n-propylamine

methyl 3-bromo-5-(dipropylcarbamoyl)benzoate
388071-08-7

methyl 3-bromo-5-(dipropylcarbamoyl)benzoate

Conditions
ConditionsYield
Stage #1: 3-bromo-5-(methoxycarbonyl)benzoic acid With HATU In N,N-dimethyl-formamide at 20℃; for 0.166667h;
Stage #2: di-n-propylamine In N,N-dimethyl-formamide at 20℃;
99.5%
Multi-step reaction with 3 steps
1: 75 percent / CDI / CH2Cl2 / 5 h / 20 °C
2: 70 percent / H2 / Pd/C / 18 h / 2585.81 Torr
3: 75 percent / butyl nitrite; copper(II) bromide / acetonitrile / 2 h / 20 °C
View Scheme
carbon disulfide
75-15-0

carbon disulfide

di-n-propylamine
142-84-7

di-n-propylamine

tetrapropyl thiuram disulfide
2556-42-5

tetrapropyl thiuram disulfide

Conditions
ConditionsYield
With oxygen In isopropyl alcohol at 50℃; under 1275.13 Torr; for 1.41667h; Autoclave;99.2%
Stage #1: carbon disulfide; di-n-propylamine With potassium hydroxide In tetrahydrofuran; water at 20℃; for 12h;
Stage #2: With iodine In tetrahydrofuran; methanol; water at 20℃; for 1h;
73%
With oxygen; eosin Y disodium salt In methanol under 3750.38 Torr; for 0.333333h; Solvent; Flow reactor; Irradiation; Green chemistry;69%
p-carboxyphenylsulfonyl chloride
10130-89-9

p-carboxyphenylsulfonyl chloride

di-n-propylamine
142-84-7

di-n-propylamine

4-[(dipropylamino)sulfonyl]benzoic acid
57-66-9

4-[(dipropylamino)sulfonyl]benzoic acid

Conditions
ConditionsYield
In dichloromethane at 0 - 20℃; for 18h;99%
With sodium hydrogencarbonate In water; acetone at 25℃; Schotten-Baumann Reaction; Flow reactor;78%
di-n-propylamine
142-84-7

di-n-propylamine

methyl isocyanate
624-83-9

methyl isocyanate

1,1-dipropyl-3-methylurea
36614-21-8

1,1-dipropyl-3-methylurea

Conditions
ConditionsYield
In diethyl ether cooling;99%
formaldehyd
50-00-0

formaldehyd

di-n-propylamine
142-84-7

di-n-propylamine

phenylacetylene
536-74-3

phenylacetylene

3-phenyl-N,N-dipropylprop-2-yn-1-amine
153396-18-0

3-phenyl-N,N-dipropylprop-2-yn-1-amine

Conditions
ConditionsYield
With Cu(2-hydroxypyrimidinolate)2 In 1,4-dioxane at 39.84℃; for 21h; Inert atmosphere;99%
With copper(l) iodide In water; dimethyl sulfoxide at 30℃; for 5h;87%
With copper(l) iodide In 1,4-dioxane Heating;
di-n-propylamine
142-84-7

di-n-propylamine

(4aS,9bR)-4-[1-Dimethylamino-meth-(E)-ylidene]-8,9b-dimethyl-1,4,4a,9b-tetrahydro-2H-dibenzofuran-3-one
86657-79-6

(4aS,9bR)-4-[1-Dimethylamino-meth-(E)-ylidene]-8,9b-dimethyl-1,4,4a,9b-tetrahydro-2H-dibenzofuran-3-one

(4aS,9bR)-4-[1-Dipropylamino-meth-(E)-ylidene]-8,9b-dimethyl-1,4,4a,9b-tetrahydro-2H-dibenzofuran-3-one
86657-94-5

(4aS,9bR)-4-[1-Dipropylamino-meth-(E)-ylidene]-8,9b-dimethyl-1,4,4a,9b-tetrahydro-2H-dibenzofuran-3-one

Conditions
ConditionsYield
In benzene for 8h; Heating;99%
2-chloro-5-nitrobenzoic acid
2516-96-3

2-chloro-5-nitrobenzoic acid

di-n-propylamine
142-84-7

di-n-propylamine

2-(dipropylamino)-5-nitrobenzoic acid

2-(dipropylamino)-5-nitrobenzoic acid

Conditions
ConditionsYield
at 100℃; for 0.0833333h; microwave irradiation;99%
With copper; potassium carbonate In N,N-dimethyl-formamide at 25℃; for 0.333333h; Ullmann condensation; ultrasonic irradiation;79%
3-iodophenylacetic acid
1878-69-9

3-iodophenylacetic acid

di-n-propylamine
142-84-7

di-n-propylamine

2-(3-iodo-phenyl)-N,N-dipropyl-acetamide
865178-30-9

2-(3-iodo-phenyl)-N,N-dipropyl-acetamide

Conditions
ConditionsYield
With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane for 20h;99%

Dipropylamine Chemical Properties

IUPAC: N-propylpropan-1-amine 
Molecular Formula of Dipropylamine (CAS NO.142-84-7): C6H15N
Molecular Weight: 101.19
Synonyms of Dipropylamine (CAS NO.142-84-7): n,n-dipropylamine 1-Propanamine, N-propyl- ; Di-n-propylamine ; Dipropylamine ; Dipropylamine [UN2383] [Flammable liquid] ; RCRA waste no. U110 ; UN2383
Refractive index: n20/D 1.4049(lit.)
CAS NO: 142-84-7
Polar Surface Area: 3.24 Å2
Index of Refraction: 1.405
Molar Refractivity: 33.44 cm3
Molar Volume: 136.3 cm3
Surface Tension: 23 dyne/cm
Flash Point: 3.9 °C
Enthalpy of Vaporization: 33.47 kJ/mol 
Index of Refraction: 1.405
Density: 0.741 g/cm3
Boiling Point: 108.8 °C at 760 mmHg
Vapour Pressure: 25.5 mmHg at 25°C 
Stability: Stable. Highly flammable. Incompatible with strongoxidizing agents
The Structure of Dipropylamine (CAS NO.142-84-7):

Dipropylamine Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mammal (species unspecified) LC50 inhalation 4400mg/m3 (4400mg/m3)   Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 14, Pg. 80, 1975.
mammal (species unspecified) LD50 unreported 600mg/kg (600mg/kg)   Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 14, Pg. 80, 1975.
mouse LC50 inhalation 3070mg/m3/2H (3070mg/m3)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 63, 1982.
mouse LD50 unreported 320mg/kg (320mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(4), Pg. 103, 1970.
rabbit LD50 skin 925mg/kg (925mg/kg)   National Technical Information Service. Vol. OTS0535430,
rabbit LD50 subcutaneous 1250mg/kg (1250mg/kg)   "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 434, 1986.
rat LC50 inhalation 4400mg/m3/4H (4400mg/m3)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 63, 1982.
rat LD50 oral 300mg/kg (300mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: MUSCLE WEAKNESS
National Technical Information Service. Vol. OTS0544865,
rat LD50 unreported 280mg/kg (280mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(4), Pg. 103, 1970.
rat LDLo intraperitoneal 75mg/kg (75mg/kg)   Farmakologiya i Toksikologiya Vol. 31, Pg. 238, 1968.

Dipropylamine Consensus Reports

Reported in EPA TSCA Inventory.

Dipropylamine Safety Profile

Poison by ingestion. Moderately toxic by skin contact and inhalation. A skin irritant. A very dangerous fire hazard, when exposed to heat or flame. Can react with oxidizers. Explosion hazard is unknown. Keep away from heat and open flame. To fight fire, use foam, CO2, dry chemical. When heated to decomposition it emits toxic fumes of NOx.
Safety Information of  Dipropylamine (CAS NO.142-84-7):
Hazard Codes: F :  ,C
 Risk Statements: 11-20/21/22-35  (  Highly Flammable ; Harmful by inhalation, in contact with skin and if swallowed  ; Causes severe burns
Safety Statements  16-26-36/37/39-45 [Keep away from sources of ignition - No smoking ; In case of contact with eyes, rinse immediately with plenty of water and seek medical advice ; Wear suitable protective clothing, gloves and eye/face protection ; In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) ] RIDADR  UN 2383 3/PG 2
 WGK Germany :1
 RTECS : JL9200000
 HazardClass :3
PackingGroup:  II

Dipropylamine Standards and Recommendations

DOT Classification:  3; Label: Flammable Liquid

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