Product Name

  • Name

    1,2-Epoxy ethane

  • EINECS 200-849-9
  • CAS No. 75-21-8
  • Article Data191
  • CAS DataBase
  • Density 0.995 g/cm3
  • Solubility
  • Melting Point - 111 °C(lit.)
  • Formula C2H4O
  • Boiling Point 10.699 °C at 760 mmHg
  • Molecular Weight 44.0532
  • Flash Point 低于-17.7oC
  • Transport Information UN 2037 2.3
  • Appearance clear colorless gas with an ethereal odor
  • Safety 53-45-36/37-16-24/25-23
  • Risk Codes 45-46-12-23-36/37/38
  • Molecular Structure Molecular Structure of 75-21-8 (1,2-Epoxy ethane)
  • Hazard Symbols HighlyF+; ToxicT
  • Synonyms Ethyleneoxide (8CI);Ethyleneoxy (6CI);1,2-Epoxyethane;Dihydrooxirene;Dimethylene oxide;ETO;Epoxyethane;Ethene oxide;Oxacyclopropane;Oxane;Oxidoethane;Oxirene, dihydro-;Oxyfume;Oxyfume 12;Oxyfume 2002;T-Gas;
  • PSA 12.53000
  • LogP 0.01660

Synthetic route

2-chloro-ethanol
107-07-3

2-chloro-ethanol

oxirane
75-21-8

oxirane

Conditions
ConditionsYield
With sodium hydroxide at 60 - 70℃; Reagent/catalyst; Temperature;97.97%
With -base at 25℃;
With potassium hydroxide
C20H13AsF12O3
1243300-84-6

C20H13AsF12O3

A

oxirane
75-21-8

oxirane

B

C18H8AsF12O2(1-)*K(1+)

C18H8AsF12O2(1-)*K(1+)

Conditions
ConditionsYield
With potassium hydride In [D3]acetonitrile at 0 - 45℃; for 10.6667h; Inert atmosphere;A n/a
B 96%
ethene
74-85-1

ethene

oxirane
75-21-8

oxirane

Conditions
ConditionsYield
With nitrogen; chloroethane; carbon dioxide; oxygen; silver and cesium in alpha-aluminum oxide support at 225℃; under 12001.2 Torr; Product distribution / selectivity; Microchannel reactor;92.7%
With oxygen at 225℃; Reagent/catalyst; Temperature; Inert atmosphere;21.28%
With sulfur dioxide; phosphorus-vanadium-titanium catalyst KFK-77 at 400℃;20%
1,2-dichloro-ethane
107-06-2

1,2-dichloro-ethane

oxirane
75-21-8

oxirane

Conditions
ConditionsYield
With potassium hydroxide; sodium formate; Aliquat 336 at 105℃; for 0.25h;70%
ethyl acetoacetate
141-97-9

ethyl acetoacetate

ethylene dibromide
106-93-4

ethylene dibromide

A

oxirane
75-21-8

oxirane

B

ethyl 1-acetylcyclopropanecarboxylate
32933-03-2

ethyl 1-acetylcyclopropanecarboxylate

C

ethylene glycol
107-21-1

ethylene glycol

Conditions
ConditionsYield
With tetraethylammonium perchlorate In N,N-dimethyl-formamide electrolysis;A n/a
B 22%
C n/a
ethylene dibromide
106-93-4

ethylene dibromide

diethyl malonate
105-53-3

diethyl malonate

A

oxirane
75-21-8

oxirane

B

diethyl cyclopropane-1,1-dicarboxylate
1559-02-0

diethyl cyclopropane-1,1-dicarboxylate

C

ethylene glycol
107-21-1

ethylene glycol

Conditions
ConditionsYield
With tetraethylammonium perchlorate In N,N-dimethyl-formamide electrolysis;A n/a
B 13%
C n/a
ethylene dibromide
106-93-4

ethylene dibromide

malonic acid dimethyl ester
108-59-8

malonic acid dimethyl ester

A

oxirane
75-21-8

oxirane

B

dimethyl 1,1-cyclopropanedicarboxylate
6914-71-2

dimethyl 1,1-cyclopropanedicarboxylate

C

ethylene glycol
107-21-1

ethylene glycol

Conditions
ConditionsYield
With tetraethylammonium perchlorate In N,N-dimethyl-formamide electrolysis;A n/a
B 11%
C n/a
ethane
74-84-0

ethane

oxirane
75-21-8

oxirane

Conditions
ConditionsYield
With oxygen at 310℃;1.2%
With oxygen; Ni-Nb-O mixed oxides on γ-alumina (15% Ni, 4.02% Nb); Ag/γ-alumina (15% Ag) at 350℃; under 7500.75 Torr; Product distribution / selectivity;
With oxygen; Ag/γ-alumina (15% Ag) at 350℃; under 7500.75 Torr; Product distribution / selectivity;
[1,3]-dioxolan-2-one
96-49-1

[1,3]-dioxolan-2-one

A

oxirane
75-21-8

oxirane

B

methylammonium carbonate
15719-64-9, 15719-76-3, 97762-63-5

methylammonium carbonate

Conditions
ConditionsYield
at 200℃; Pyrolysis;
Perbenzoic acid
93-59-4

Perbenzoic acid

ethene
74-85-1

ethene

oxirane
75-21-8

oxirane

Conditions
ConditionsYield
With iodine; 1,1,2,2-tetrachloroethane
1-chloro-2-iodoethane
624-70-4

1-chloro-2-iodoethane

oxirane
75-21-8

oxirane

Conditions
ConditionsYield
With sodium oxide at 180℃;
1,2-Diiodoethane
624-73-7

1,2-Diiodoethane

oxirane
75-21-8

oxirane

Conditions
ConditionsYield
With silver(l) oxide at 150℃;
2-chloro-1-acetoxyethane
542-58-5

2-chloro-1-acetoxyethane

oxirane
75-21-8

oxirane

Conditions
ConditionsYield
With sodium hydroxide
ethene
74-85-1

ethene

1,2-dichloro-ethane
107-06-2

1,2-dichloro-ethane

oxirane
75-21-8

oxirane

ethylene dibromide
106-93-4

ethylene dibromide

oxirane
75-21-8

oxirane

Conditions
ConditionsYield
With silver(l) oxide at 250℃;
With sodium oxide at 180℃;
2-(Diethylamino)ethanol
100-37-8

2-(Diethylamino)ethanol

A

oxirane
75-21-8

oxirane

B

diethylamine
109-89-7

diethylamine

Conditions
ConditionsYield
at 25℃;
2-chloro-ethanol
107-07-3

2-chloro-ethanol

A

oxirane
75-21-8

oxirane

B

N,N-di(2-hydroxyethyl)hydrazine
13529-51-6

N,N-di(2-hydroxyethyl)hydrazine

Conditions
ConditionsYield
With hydrazine
trimethylene oxide
503-30-0

trimethylene oxide

A

oxirane
75-21-8

oxirane

B

methoxyethene
107-25-5

methoxyethene

C

2-methoxy-ethanol
109-86-4

2-methoxy-ethanol

Conditions
ConditionsYield
With methane; water; oxygen at 37.5℃; Mechanism; Product distribution; Thermodynamic data; Irradiation; ΔH0;
2-(ethoxymethyl)oxirane
4016-11-9

2-(ethoxymethyl)oxirane

2-(phenylselenyl)ethanol
65275-32-3

2-(phenylselenyl)ethanol

A

oxirane
75-21-8

oxirane

B

1-Ethoxy-3-phenylselanyl-propan-2-ol

1-Ethoxy-3-phenylselanyl-propan-2-ol

Conditions
ConditionsYield
at 159℃; for 5.5h;
1,3,5-Trioxan
110-88-3

1,3,5-Trioxan

A

oxirane
75-21-8

oxirane

B

carbon dioxide
124-38-9

carbon dioxide

Conditions
ConditionsYield
In water Quantum yield; Irradiation;
epoxybutene
930-22-3

epoxybutene

2-(phenylselenyl)ethanol
65275-32-3

2-(phenylselenyl)ethanol

A

oxirane
75-21-8

oxirane

B

(+/-)-1-(phenylseleno)-but-3-en-2-ol
21113-89-3

(+/-)-1-(phenylseleno)-but-3-en-2-ol

Conditions
ConditionsYield
at 159℃; for 5.5h;
epoxybutene
930-22-3

epoxybutene

2-diphenylphosphinoethanol
2360-04-5

2-diphenylphosphinoethanol

A

oxirane
75-21-8

oxirane

B

ethene
74-85-1

ethene

C

acetaldehyde
75-07-0

acetaldehyde

Conditions
ConditionsYield
In chlorobenzene at 100℃; for 1h; Mechanism; a new decomposition path of reaction;
glycidyl n-butyl ether
2426-08-6

glycidyl n-butyl ether

2-(phenylselenyl)ethanol
65275-32-3

2-(phenylselenyl)ethanol

A

oxirane
75-21-8

oxirane

B

1-butoxy-3-(phenylselanyl)propan-2-ol
84866-67-1

1-butoxy-3-(phenylselanyl)propan-2-ol

Conditions
ConditionsYield
at 159℃; for 5.5h;
thiirane-1,1-dioxide
1782-89-4

thiirane-1,1-dioxide

oxirane
75-21-8

oxirane

Conditions
ConditionsYield
vanadia at 350℃; flow-type reactor;0.2 g
vanadia at 350℃; Product distribution; flow-type reactor;0.2 g
styrene oxide
96-09-3

styrene oxide

2-(phenylselenyl)ethanol
65275-32-3

2-(phenylselenyl)ethanol

A

oxirane
75-21-8

oxirane

B

1-phenyl-2-(phenylselanyl)ethanol
51558-95-3

1-phenyl-2-(phenylselanyl)ethanol

Conditions
ConditionsYield
at 159℃; for 5.5h;
styrene oxide
96-09-3

styrene oxide

2-diphenylphosphinoethanol
2360-04-5

2-diphenylphosphinoethanol

A

oxirane
75-21-8

oxirane

B

styrene
292638-84-7

styrene

C

ethene
74-85-1

ethene

D

acetaldehyde
75-07-0

acetaldehyde

E

acetophenone
98-86-2

acetophenone

Conditions
ConditionsYield
In chlorobenzene at 150℃; for 1h; Mechanism; a new decomposition path of reaction;
β-Propiolactone
57-57-8

β-Propiolactone

A

oxirane
75-21-8

oxirane

B

methane
34557-54-5

methane

C

ethene
74-85-1

ethene

D

acetaldehyde
75-07-0

acetaldehyde

Conditions
ConditionsYield
With mercury at 100℃; Product distribution; Irradiation; other reagent, other temperature;
2,5-dimethylhexane
592-13-2

2,5-dimethylhexane

A

oxirane
75-21-8

oxirane

B

isobutene
115-11-7

isobutene

Conditions
ConditionsYield
With oxygen at 500℃; under 15 Torr; for 0.00833333h; Kinetics; Rate constant; Mechanism; variation of temperature, and pressure;
carbon tetrafluoride
75-73-0

carbon tetrafluoride

ethene
74-85-1

ethene

A

oxirane
75-21-8

oxirane

B

acetaldehyde
75-07-0

acetaldehyde

Conditions
ConditionsYield
With oxygen for 0.5h; Product distribution; also without CF4;A 1.2 mol
B 6.7 mol
t-butyl 2-hydroxyethyl peroxide
15476-85-4

t-butyl 2-hydroxyethyl peroxide

A

oxirane
75-21-8

oxirane

B

glycolic Acid
79-14-1

glycolic Acid

C

methane
34557-54-5

methane

D

Glycolaldehyde
141-46-8

Glycolaldehyde

E

acetone
67-64-1

acetone

F

tert-butyl alcohol
75-65-0

tert-butyl alcohol

Conditions
ConditionsYield
In water at 99.9 - 149.9℃; Thermodynamic data; Kinetics; Product distribution; further solvent; various pH; in the presence of FeCl2 also; in glass and steel test tube in the presence of HCl; activation energy;
oxirane
75-21-8

oxirane

trimethylsilyl cyanide
7677-24-9

trimethylsilyl cyanide

3-trimethylsilanyloxypropionitrile
42202-44-8

3-trimethylsilanyloxypropionitrile

Conditions
ConditionsYield
With isopropoxydiisobutylaluminum In hexane Product distribution; Ambient temperature; other oxiranes; var. Lewis acids; var. solvents; var. temperatures;100%
With aluminum isopropoxide 1.) RT, 2 h, 2.) RT, 15 h; Yield given. Multistep reaction;
oxirane
75-21-8

oxirane

3-bromo-2,4-dimethylpenta-1,3-diene
4773-87-9

3-bromo-2,4-dimethylpenta-1,3-diene

3-isopropenyl-4-methyl-pent-3-en-1-ol
121287-11-4

3-isopropenyl-4-methyl-pent-3-en-1-ol

Conditions
ConditionsYield
Stage #1: 3-bromo-2,4-dimethylpenta-1,3-diene With tert.-butyl lithium In tetrahydrofuran at -78℃; for 0.166667h; Metallation;
Stage #2: oxirane In tetrahydrofuran at -78 - 0℃; Substitution;
100%
Stage #1: 3-bromo-2,4-dimethylpenta-1,3-diene With tert.-butyl lithium In tetrahydrofuran; pentane at -78℃; for 0.5h;
Stage #2: oxirane In tetrahydrofuran; pentane at -78 - 21℃; for 2h;
83%
With tert.-butyl lithium -78 deg C to 21 deg C;78%
oxirane
75-21-8

oxirane

carbon dioxide
124-38-9

carbon dioxide

[1,3]-dioxolan-2-one
96-49-1

[1,3]-dioxolan-2-one

Conditions
ConditionsYield
With 3-(2-hydroxylethyl)-1-(3-aminopropyl)imidazolium bromide grafted onto divinylbenzene polymer (PDVB-HEIMBr) at 140℃; under 15001.5 Torr; for 3h; Autoclave;100%
With bis[(1R,2R)-N,N'-bis(3,5-di-tert-butyl-salicylidene)cyclohexane-1,2-diaminoaluminium(III)]oxide; tetrabutylammomium bromide at 26℃; under 2280.15 Torr; for 24h;100%
With choline chloride; zinc dibromide at 110℃; under 11251.1 Torr; for 1h; Autoclave; neat (no solvent);100%
oxirane
75-21-8

oxirane

N-(1-chlorohexafluoro-1-methylethyl)benzenesulfinimidoyl chloride
85095-40-5

N-(1-chlorohexafluoro-1-methylethyl)benzenesulfinimidoyl chloride

C11H9Cl2F6NOS
91363-13-2

C11H9Cl2F6NOS

Conditions
ConditionsYield
In tetrachloromethane at 25℃; for 48h;100%
oxirane
75-21-8

oxirane

N-(2-chlorohexafluoroisopropyl)-p-toluenesulfinimidoyl chloride
85095-41-6

N-(2-chlorohexafluoroisopropyl)-p-toluenesulfinimidoyl chloride

C12H11Cl2F6NOS
91363-14-3

C12H11Cl2F6NOS

Conditions
ConditionsYield
In tetrachloromethane at 25℃; for 48h;100%
oxirane
75-21-8

oxirane

N-(2-chlorohexafluoroisopropyl)-p-nitrobenzenesulfinimidoyl chloride
85095-42-7

N-(2-chlorohexafluoroisopropyl)-p-nitrobenzenesulfinimidoyl chloride

C11H8Cl2F6N2O3S
91363-15-4

C11H8Cl2F6N2O3S

Conditions
ConditionsYield
In tetrachloromethane at 25℃; for 48h;100%
oxirane
75-21-8

oxirane

C13H18N2O2

C13H18N2O2

C17H26N2O4

C17H26N2O4

Conditions
ConditionsYield
In methanol at 5 - 7℃; for 336h;100%
oxirane
75-21-8

oxirane

C12H16N2O3

C12H16N2O3

C16H24N2O5

C16H24N2O5

Conditions
ConditionsYield
In methanol at 5 - 7℃; for 336h;100%
oxirane
75-21-8

oxirane

C14H20N2O3

C14H20N2O3

C18H28N2O5

C18H28N2O5

Conditions
ConditionsYield
In methanol at 5 - 7℃; for 336h;100%
oxirane
75-21-8

oxirane

(2-methoxy-5-methylphenyl)phenylmethane

(2-methoxy-5-methylphenyl)phenylmethane

3-(2-methoxy-5-methylphenyl)-3-phenylpropan-1-ol
124937-73-1

3-(2-methoxy-5-methylphenyl)-3-phenylpropan-1-ol

Conditions
ConditionsYield
Stage #1: oxirane; (2-methoxy-5-methylphenyl)phenylmethane With n-butyllithium In tetrahydrofuran at -78 - 20℃; for 4h;
Stage #2: With water; ammonium chloride In tetrahydrofuran
100%
oxirane
75-21-8

oxirane

phenobarbital
50-06-6

phenobarbital

5-ethyl-1,3-bis-(2-hydroxy-ethyl)-5-phenyl-pyrimidine-2,4,6-trione
29972-37-0

5-ethyl-1,3-bis-(2-hydroxy-ethyl)-5-phenyl-pyrimidine-2,4,6-trione

Conditions
ConditionsYield
With tetraethylammonium chloride In N-methyl-acetamide100%
oxirane
75-21-8

oxirane

(naphthalene)Yb(THF)3

(naphthalene)Yb(THF)3

A

naphthalene
91-20-3

naphthalene

B

Butane-1,4-diol
110-63-4

Butane-1,4-diol

C

ytterbium hydroxide

ytterbium hydroxide

Conditions
ConditionsYield
With hydrogen cation In tetrahydrofuran shaken for 10 min at room temp.; centrifuged, decanted, soln. contains naphthalene, pptn. hydrolysed in THF: butanediol detd. by GLC in the organic layer and a pptn. (Yb(OH)3);A 83%
B 100%
C 75%
oxirane
75-21-8

oxirane

ricinus oil

ricinus oil

1-amino-3-(dimethylamino)propane
109-55-7

1-amino-3-(dimethylamino)propane

dimethyl sulfate
77-78-1

dimethyl sulfate

Dehyquart AU 39

Dehyquart AU 39

Conditions
ConditionsYield
Stage #1: oxirane; ricinus oil; 1-amino-3-(dimethylamino)propane With sodium tetrahydroborate; sodium methylate In methanol at 130℃; for 2h;
Stage #2: dimethyl sulfate at 65℃; for 4h;
100%
oxirane
75-21-8

oxirane

4-(4-(trifluoromethoxy)phenoxy)piperidine
287952-67-4

4-(4-(trifluoromethoxy)phenoxy)piperidine

2-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)ethanol
1346017-80-8

2-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)ethanol

Conditions
ConditionsYield
at 0℃; for 0.833333h;100%
In dichloromethane at 0℃; for 3h;100%
oxirane
75-21-8

oxirane

7-morpholino-6-nitro-3,4-dihydroquinolin-2(1H)-one

7-morpholino-6-nitro-3,4-dihydroquinolin-2(1H)-one

1-(2-hydroxyethyl)-7-morpholino-6-nitro-3,4-dihydroquinolin-2(1H)-one

1-(2-hydroxyethyl)-7-morpholino-6-nitro-3,4-dihydroquinolin-2(1H)-one

Conditions
ConditionsYield
Stage #1: 7-morpholino-6-nitro-3,4-dihydroquinolin-2(1H)-one With sodium hydride In N,N-dimethyl-formamide; mineral oil at 60℃; for 0.5h;
Stage #2: oxirane In N,N-dimethyl-formamide; mineral oil at 60℃; for 18h;
100%
oxirane
75-21-8

oxirane

ethyl (2S)-2-[[(2S)-3-(4-aminophenyl)-2-(tert-butoxycarbonylamino)propanoyl]amino]-3-(4-fluorophenyl)propanoate

ethyl (2S)-2-[[(2S)-3-(4-aminophenyl)-2-(tert-butoxycarbonylamino)propanoyl]amino]-3-(4-fluorophenyl)propanoate

C29H40FN3O7

C29H40FN3O7

Conditions
ConditionsYield
In tetrahydrofuran; methanol Inert atmosphere;100%
oxirane
75-21-8

oxirane

methyloxirane
75-56-9, 16033-71-9

methyloxirane

recorcinol
108-46-3

recorcinol

C38H70O14

C38H70O14

Conditions
ConditionsYield
Stage #1: methyloxirane; recorcinol With potassium hydroxide In toluene at 48.8789℃; for 1.5h; Under N2;
Stage #2: oxirane at 48.8789℃; for 2h;
99.7%
oxirane
75-21-8

oxirane

p-acetylaminobenzenesulfonyl chloride
121-60-8

p-acetylaminobenzenesulfonyl chloride

2-(p-aminophenylsulfonyl)ethyl hydrogen sulfate
2494-89-5

2-(p-aminophenylsulfonyl)ethyl hydrogen sulfate

Conditions
ConditionsYield
Stage #1: p-acetylaminobenzenesulfonyl chloride With sodium metabisulfite; sodium hydroxide at 30℃; pH=7 - 7.5;
Stage #2: oxirane at 40℃; pH=7.5 - 8;
Stage #3: With sulfuric acid at 150 - 160℃; under 3750.38 Torr;
99.7%
oxirane
75-21-8

oxirane

2,2'-thiobis-ethanol
111-48-8

2,2'-thiobis-ethanol

Conditions
ConditionsYield
With hydrogen sulfide at 20℃; Temperature;99.5%
With hydrogen sulfide
oxirane
75-21-8

oxirane

sodium 2-hydroxyethanesulfonate
1562-00-1

sodium 2-hydroxyethanesulfonate

Conditions
ConditionsYield
With sodium hydrogen sulfate at 40℃; for 0.25h; Temperature; Large scale;99.5%
With water; sodium hydrogensulfite
With sodium metabisulfite
oxirane
75-21-8

oxirane

N-ethyl-N-phenylamine
103-69-5

N-ethyl-N-phenylamine

2-( N-ethylanilino)ethanol
92-50-2

2-( N-ethylanilino)ethanol

Conditions
ConditionsYield
With Tau at 102 - 133℃; for 4h; Temperature; Autoclave; Inert atmosphere; Industrial scale;99.4%
With methanol
With water at 100℃; im Rohr;

Ethylene oxide History

  Ethylene oxide (CAS NO.75-21-8) prepared it by treating 2-chloroethanol with a base. It was first reported in 1859 by the French chemist Charles-Adolphe Wurtz, it achieved industrial importance during World War I as a precursor to both the coolant ethylene glycol and the chemical weapon mustard gas. In 1931, Theodore Lefort, another French chemist, discovered a means to prepare ethylene oxide directly from ethylene and oxygen, using silver as a catalyst. Since 1940, almost all ethylene oxide(75-21-8) produced industrially has been made using this method. Ethylene oxide(75-21-8) sterilization for the preservation of spices was patented in 1938 by the American chemist Lloyd Hall, and it is still used in that role.
 

Ethylene oxide Specification

The Ethylene oxide, with the CAS registry number 75-21-8 and EINECS registry number 200-849-9, has the systematic name of oxirane. And the molecular formula of this chemical is C2H4O. It is a kind of colorless gas with a faintly sweet odor, and belongs to the following product categories: Organics; Oxiranes; Simple 3-Membered Ring Compounds; Fumigants Chromatography; General Use; Air Monitoring Standards; Alpha Sort; E; E-LAlphabetic; Insecticides; Volatiles/ Semivolatiles.

The Ethylene oxide, also known as oxirane, is a cyclic ether. It is the simplest epoxide, and because of its special molecular structure, it easily participates in the addition reaction, opening its cycle, and thus easily polymerizes. What's more, it is isomeric with acetaldehyde.
 
The physical properties of Ethylene oxide are as following: (1)# of Rule of 5 Violations: 0; (2)ACD/BCF (pH 5.5): 1; (3)ACD/BCF (pH 7.4): 1; (4)ACD/KOC (pH 5.5): 11.501; (5)ACD/KOC (pH 7.4): 11.501; (6)#H bond acceptors: 1; (7)#H bond donors: 0; (8)#Freely Rotating Bonds: 0; (9)Polar Surface Area: 12.53 Å2; (10)Index of Refraction: 1.404; (11)Molar Refractivity: 10.829 cm3; (12)Molar Volume: 44.283 cm3; (13)Polarizability: 4.293×10-24cm3; (14)Surface Tension: 31.257 dyne/cm; (15)ensity: 0.995 g/cm3; (16)Enthalpy of Vaporization: 25.54 kJ/mol; (17)Boiling Point: 10.699 °C at 760 mmHg; (18)Vapour Pressure: 1255.443 mmHg at 25°C.

Preparation of Ethylene oxide: It is industrially produced by direct oxidation of ethylene in the presence of silver catalyst. It can also be prepared by treating 2-chloroethanol with potassium hydroxide:
Cl–CH2CH2–OH + KOH → (CH2CH2)O + KCl + H2O

Uses of Ethylene oxide: It is one of the most important raw materials used in the large-scale chemical production. It is used for synthesis of ethylene glycols, including diethylene glycol and triethylene glycol. It is also used for the synthesis of ethylene glycol ethers, ethanolamines and ethoxylates. What's more, it is a bactericidal, fungicidal, and sporicidal disinfectant. It is effective against most micro-organisms, including viruses. In addition, it is used as a fumigant for foodstuffs and textiles and as an agent for the gaseous sterilization of heat-labile pharmaceutical and surgical materials. Last but not the least, it is extremely flammable and explosive and is used as a main component of thermobaric weapons.

You should be cautious while dealing with this chemical. It is a highly flammable chemical which irritates eyes, respiratory system and skin. It has danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed. What's more, it may cause cancer and heritable genetic damage. Therefore, you had better take the following instructions: Wear suitable protective clothing and gloves; Avoid contact with skin and eyes; Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer); Keep away from sources of ignition - No smoking; In case of accident or if you feel unwell, seek medical advice immediately (show label where possible); Avoid exposure - obtain special instruction before use.

You can still convert the following datas into molecular structure:
(1)SMILES: C1CO1
(2)InChI: InChI=1/C2H4O/c1-2-3-1/h1-2H2
(3)InChIKey: IAYPIBMASNFSPL-UHFFFAOYAX

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo subcutaneous 100mg/kg (100mg/kg)   "Beitrage zur Toxikologie des Athylenoxyds und der Glykole, Dissertation," Hofbauer, A., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1933Vol. -, Pg. -, 1933.
dog LC50 inhalation 960ppm/4H (960ppm) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

GASTROINTESTINAL: NAUSEA OR VOMITING

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
AMA Archives of Industrial Health. Vol. 13, Pg. 237, 1956.
dog LD50 intravenous 330mg/kg (330mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

GASTROINTESTINAL: NAUSEA OR VOMITING

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Thoracic and Cardiovascular Surgery. Vol. 61, Pg. 309, 1971.
guinea pig LC50 inhalation 1500mg/m3/4H (1500mg/m3)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 67, 1982.
guinea pig LD50 oral 270mg/kg (270mg/kg)   Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.
human TCLo inhalation 12500ppm/10S (12500ppm) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION Journal of Hygiene. Vol. 32, Pg. 409, 1932.
mouse LC50 inhalation 836ppm/4H (836ppm)   National Technical Information Service. Vol. PB214-270,
mouse LD50 intraperitoneal 175mg/kg (175mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 48(1), Pg. 23, 1983.
mouse LD50 intravenous 290mg/kg (290mg/kg)   Acta Pharmacologica et Toxicologica. Vol. 43, Pg. 69, 1978.
rabbit LDLo intravenous 175mg/kg (175mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: REGIDITY
Journal of Hygiene. Vol. 32, Pg. 409, 1932.
rat LC50 inhalation 800ppm/4H (800ppm) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

KIDNEY, URETER, AND BLADDER: OTHER CHANGES

LIVER: OTHER CHANGES
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 258, 1969.
rat LD50 oral 72mg/kg (72mg/kg)   Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 17, 1978.
rat LD50 subcutaneous 187mg/kg (187mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 48(1), Pg. 23, 1983.
rat LDLo unreported 200mg/kg (200mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

LIVER: OTHER CHANGES

KIDNEY, URETER, AND BLADDER: OTHER CHANGES
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 258, 1969.
women TCLo inhalation 500ppm/2M (500ppm) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

GASTROINTESTINAL: NAUSEA OR VOMITING

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Drug Intelligence and Clinical Pharmacy. Vol. 15, Pg. 384, 1981.

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