Product Name

  • Name

    Glycyl-glycyl-glycine

  • EINECS 209-122-0
  • CAS No. 556-33-2
  • Article Data39
  • CAS DataBase
  • Density 1.373 g/cm3
  • Solubility H2O: 0.5 M at 20 °C, clear, colorless
  • Melting Point 240-250 °C
  • Formula C6H11N3O4
  • Boiling Point 638.8 °C at 760 mmHg
  • Molecular Weight 189.171
  • Flash Point 340.1 °C
  • Transport Information
  • Appearance white crystalline powder
  • Safety
  • Risk Codes
  • Molecular Structure Molecular Structure of 556-33-2 (Glycyl-glycyl-glycine)
  • Hazard Symbols
  • Synonyms Glycylglycylglycine;gly-l-gly-l-gly;N-(N-Glycylglycyl)glycine;
  • PSA 121.52000
  • LogP -1.25580

Synthetic route

DL-phenylalanine methyl ester
15028-44-1

DL-phenylalanine methyl ester

1-O-(glycylglycylglycyl)-β-D-glucopyranose
75719-94-7

1-O-(glycylglycylglycyl)-β-D-glucopyranose

A

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

B

glycylglycylglycyl-D,L-phenylalanine methyl ester
84814-47-1

glycylglycylglycyl-D,L-phenylalanine methyl ester

Conditions
ConditionsYield
With 4-methyl-morpholine In N,N-dimethyl-formamide at 38℃; for 72h;A 67%
B 92%
With 4-methyl-morpholine In N,N-dimethyl-formamide at 38℃; for 72h;A 67%
B 28%
[2-(2-Benzyloxycarbonylamino-acetylamino)-acetylamino]-acetic acid
2566-20-3

[2-(2-Benzyloxycarbonylamino-acetylamino)-acetylamino]-acetic acid

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

Conditions
ConditionsYield
With acetic acid In methanol Ambient temperature; electrolysis: palladium/graphite cathode, -0.6 V to -1.0 V SCE, current density = 15 mA/cm2, catholyte: NaClO4;90%
With cell extract of Sphingomonas paucimobilis SC 16113 In water at 42℃; for 20h; Enzymatic reaction;23 % Chromat.
tetrabutylphosphonium glycinate

tetrabutylphosphonium glycinate

glycine ethyl ester hydrochloride
5680-79-5

glycine ethyl ester hydrochloride

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

Conditions
ConditionsYield
Stage #1: tetrabutylphosphonium glycinate for 3h; Inert atmosphere;
Stage #2: glycine ethyl ester hydrochloride In chloroform at 60℃; for 24h;
Stage #3: With acetic acid In chloroform at 20℃; for 10h;
66%
glycine
56-40-6

glycine

A

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

B

N-carbamoylmethyl-glycine
7365-83-5

N-carbamoylmethyl-glycine

C

H-Gly-NH2
598-41-4

H-Gly-NH2

Conditions
ConditionsYield
With 1,2,4-Triazole; Sodium trimetaphosphate; magnesium chloride In water for 20h; Ambient temperature; var.reag.: pyrrole, pyrrolidine, pyrrazole, imidazole, tetrazole, adenine,quanine, thyamine, uracile, adenosine, quanosine,thymidine, uridine and add of MgCl2: var. pH, time and temp.;A 5.5%
B 23.6%
C 3.2%
chloroacetyldiglycine
15474-96-1

chloroacetyldiglycine

A

Glycine anhydride
106-57-0

Glycine anhydride

B

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

Conditions
ConditionsYield
With ammonia; water at 25℃;
N-carboxy-glycyl=>glycyl=>glycine
27440-17-1

N-carboxy-glycyl=>glycyl=>glycine

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

Conditions
ConditionsYield
With borax; sodium dihydrogenphosphate at 26℃; Equilibrium constant;
1-O-(glycylglycylglycyl)-β-D-glucopyranose mono-oxalate
75719-95-8

1-O-(glycylglycylglycyl)-β-D-glucopyranose mono-oxalate

A

β-D-glucose
492-61-5

β-D-glucose

B

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

Conditions
ConditionsYield
With β-D-glucosidase; nitrate buffer In water at 37℃; for 6h;
1-O-(glycylglycylglycyl)-β-D-glucopyranose
75719-94-7

1-O-(glycylglycylglycyl)-β-D-glucopyranose

A

β-D-glucose
492-61-5

β-D-glucose

B

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

Conditions
ConditionsYield
In water for 96h; decompn. with/without 0.1M HCl;
glycine
56-40-6

glycine

A

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

B

tetraglycine
637-84-3

tetraglycine

C

pentaglycine
7093-67-6

pentaglycine

D

glycylglycine
556-50-3

glycylglycine

Conditions
ConditionsYield
titanium(IV) oxide In water for 24h; Product distribution; Irradiation; reactions between var. conditions and with var. semiconductor photocatalysts with and without platinization;A 0.00021 mmol
B 0.00018 mmol
C 0.00010 mmol
D 0.01026 mmol
glycine
56-40-6

glycine

A

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

B

glycylglycine
556-50-3

glycylglycine

Conditions
ConditionsYield
With copper dichloride In water at 80 - 90℃; Mechanism; Product distribution; Rate constant; other alkali and alkaline-earth-metal cations;
Cu(2+)-doted montmorillonite In water at 80℃; Product distribution; evaporation during 24 h, 4-5 cycles; also by constant volume; natural montmorillonite as catalyst, diglycine as substrate, other products;
glycine
56-40-6

glycine

A

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

B

glycylglycine
556-50-3

glycylglycine

C

aminoacetyl phosphate

aminoacetyl phosphate

D

N-(carboxymethyl)phophoroamidate
67278-70-0

N-(carboxymethyl)phophoroamidate

Conditions
ConditionsYield
With sodium hydroxide; Sodium trimetaphosphate In water for 96h; Product distribution; Ambient temperature; variation of mixing ratio of the starting materials, pH, reaction time;A n/a
B n/a
C 25.3 % Chromat.
D 22.7 % Chromat.
With sodium hydroxide; Sodium trimetaphosphate In water for 96h; Ambient temperature; pH=12;A n/a
B n/a
C 25.3 % Chromat.
D 22.7 % Chromat.
chloroacetyldiglycine
15474-96-1

chloroacetyldiglycine

ammonium hydroxide

ammonium hydroxide

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

Conditions
ConditionsYield
at 100℃;
<dl-leucyl>-diglycyl-glycine

<dl-leucyl>-diglycyl-glycine

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

Conditions
ConditionsYield
mit Hefe-Polypeptidase bei pH 7.0;
N,N-dibenzyl-glycyl->glycyl->glycine

N,N-dibenzyl-glycyl->glycyl->glycine

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

Conditions
ConditionsYield
With palladium; acetic acid at 80℃; Hydrogenation;
N,N-phthaloyl-glycyl->glycyl->glycine

N,N-phthaloyl-glycyl->glycyl->glycine

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

Conditions
ConditionsYield
With ethanol; hydrazine hydrate
N-<(2-nitro-phenoxy)-acetyl>-glycyl->glycyl->glycine

N-<(2-nitro-phenoxy)-acetyl>-glycyl->glycyl->glycine

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

Conditions
ConditionsYield
With sodium hydrogencarbonate; platinum Hydrogenation.Erhitzen des Reaktionsprodukts mit H2O;
N-benzyloxycarbonyl-glycyl->glycyl->glycine benzyl ester

N-benzyloxycarbonyl-glycyl->glycyl->glycine benzyl ester

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

Conditions
ConditionsYield
With hydrogen bromide; acetic acid
N-benzyloxycarbonyl-glycyl->glycyl->glycine

N-benzyloxycarbonyl-glycyl->glycyl->glycine

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

Conditions
ConditionsYield
With hydrogen bromide; acetic acid
N-chloroacetyl-glycyl->glycyl->glycine

N-chloroacetyl-glycyl->glycyl->glycine

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

Conditions
ConditionsYield
With lithium hydroxide; water; 1,2-diamino-benzene
N-trifluoroacetyl-glycyl->glycyl->glycine ethyl ester

N-trifluoroacetyl-glycyl->glycyl->glycine ethyl ester

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

Conditions
ConditionsYield
With barium dihydroxide
leucyl=>glycyl=>glycyl=>glycine
91881-03-7

leucyl=>glycyl=>glycyl=>glycine

furan-2,3,5(4H)-trione pyridine (1:1)

furan-2,3,5(4H)-trione pyridine (1:1)

yeastpolypeptidase

yeastpolypeptidase

A

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

B

LEUCINE
328-39-2

LEUCINE

C

d-leucyl-diglycyl-glycine

d-leucyl-diglycyl-glycine

Conditions
ConditionsYield
dl-leucyl-diglycyl-glycine;
N-benzyloxycarbonylglycylglycylglycylglycine
7770-50-5

N-benzyloxycarbonylglycylglycylglycylglycine

papain-substances

papain-substances

A

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

B

N-(Benzyloxycarbonyl)glycine
1138-80-3

N-(Benzyloxycarbonyl)glycine

Conditions
ConditionsYield
Hydrolysis;
glycine
56-40-6

glycine

A

Glycine anhydride
106-57-0

Glycine anhydride

B

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

C

tetraglycine
637-84-3

tetraglycine

D

glycylglycine
556-50-3

glycylglycine

Conditions
ConditionsYield
With hydrogen In water at 200℃; under 187515 Torr; for 0.0333333h; Product distribution; Further Variations:; Temperatures; Reagents;
tetraglycine
637-84-3

tetraglycine

A

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

B

glycine
56-40-6

glycine

Conditions
ConditionsYield
With deuteriated sodium hydroxide; dihydrogen peroxide; water-d2 at 37℃; Kinetics;
Glycine anhydride
106-57-0

Glycine anhydride

glycine
56-40-6

glycine

A

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

B

glycylglycine
556-50-3

glycylglycine

Conditions
ConditionsYield
With water at 200℃; under 187515 Torr; pH=5.9; Kinetics;
glycylglycine
556-50-3

glycylglycine

glycine
56-40-6

glycine

A

Glycine anhydride
106-57-0

Glycine anhydride

B

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

Conditions
ConditionsYield
In water at 200℃; under 187515 Torr; pH=5.7; Kinetics;
((N-(tert-butoxycarbonyl)glycyl)glycyl)glycine
28320-73-2

((N-(tert-butoxycarbonyl)glycyl)glycyl)glycine

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

Conditions
ConditionsYield
With trifluoroacetic acid at 20℃; for 2h;
N-(fluoren-9-ylmethoxycarbonyl)glycine
29022-11-5

N-(fluoren-9-ylmethoxycarbonyl)glycine

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

Conditions
ConditionsYield
Multistep reaction.;
γ-Glu-Gly-Gly-Gly

γ-Glu-Gly-Gly-Gly

A

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

B

L-glutamic acid
56-86-0

L-glutamic acid

Conditions
ConditionsYield
With recombinant Pseudomonas nitroreducens IFO12694 γ-glutamyltranspeptidase at 30℃; for 0.0333333h; pH=10.5; aq. buffer; Enzymatic reaction;
glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

(fluorenylmethoxy)carbonyl chloride
28920-43-6

(fluorenylmethoxy)carbonyl chloride

9-fluorenylmethoxycarbonyl Gly-Gly-Gly-OH

9-fluorenylmethoxycarbonyl Gly-Gly-Gly-OH

Conditions
ConditionsYield
With sodium carbonate In tetrahydrofuran at 0 - 20℃; for 4h;100%
glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

toluene-4-sulfonic acid
104-15-4

toluene-4-sulfonic acid

cyclohexylmethyl alcohol
100-49-2

cyclohexylmethyl alcohol

[2-(2-amino-acetylamino)-acetylamino]-acetic acid cyclohexylmethyl ester; compound with toluene-4-sulfonic acid

[2-(2-amino-acetylamino)-acetylamino]-acetic acid cyclohexylmethyl ester; compound with toluene-4-sulfonic acid

Conditions
ConditionsYield
In toluene for 3h; Heating;99%
glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

((N-(tert-butoxycarbonyl)glycyl)glycyl)glycine
28320-73-2

((N-(tert-butoxycarbonyl)glycyl)glycyl)glycine

Conditions
ConditionsYield
With sodium hydrogencarbonate In N,N-dimethyl-formamide at 0 - 20℃; for 30h;98%
With sodium hydrogencarbonate In water; N,N-dimethyl-formamide at 20℃; for 1h;96%
With guanidine hydrochloride In ethanol at 35 - 40℃; for 10h;91%
formaldehyd
50-00-0

formaldehyd

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

N,N-dimethyl-glycyl=>glycyl=>glycine

N,N-dimethyl-glycyl=>glycyl=>glycine

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen In water under 3000.3 Torr; for 4h;98%
glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

Mal-Tyr-OMe
124455-85-2

Mal-Tyr-OMe

Mal-Tyr-Gly-Gly-Gly-OH
132402-94-9

Mal-Tyr-Gly-Gly-Gly-OH

Conditions
ConditionsYield
With sodium hydroxide at -13℃; for 5h; α-chymotrypsin; in ice;91.2%
glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

N-[(diethylamino)carbonothioyl]benzenecarboximidoyl chloride
82655-59-2

N-[(diethylamino)carbonothioyl]benzenecarboximidoyl chloride

C18H24N5O4S(1-)*K(1+)

C18H24N5O4S(1-)*K(1+)

Conditions
ConditionsYield
With potassium hydroxide In ethanol at 20℃; for 8h;90%
glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

n-heptan1ol
111-70-6

n-heptan1ol

toluene-4-sulfonic acid
104-15-4

toluene-4-sulfonic acid

TsOH*GGG-OC7H15

TsOH*GGG-OC7H15

Conditions
ConditionsYield
In toluene Heating;89%
In toluene Reflux; Dean-Stark;89%
glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

Z-Cys(BzlOMe)-ONSu
77374-43-7

Z-Cys(BzlOMe)-ONSu

Z-Cys(BzlOMe)-Gly3-OH
77374-44-8

Z-Cys(BzlOMe)-Gly3-OH

Conditions
ConditionsYield
With sodium hydrogencarbonate In 1,4-dioxane; water for 24h; Ambient temperature;85%
glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

N-phthaloylglycine chloride
6780-38-7

N-phthaloylglycine chloride

(2-{2-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-acetylamino]-acetylamino}-acetylamino)-acetic acid

(2-{2-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-acetylamino]-acetylamino}-acetylamino)-acetic acid

Conditions
ConditionsYield
Stage #1: glycine-glycine-glycine With magnesium oxide In water at 25℃; for 4h;
Stage #2: N-phthaloylglycine chloride In 1,4-dioxane; water at 25℃; for 2h;
85%
N-benzyloxycarbonyl-S-benzyl-L-cysteine succinimido-ester
3401-57-8

N-benzyloxycarbonyl-S-benzyl-L-cysteine succinimido-ester

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

Z-Cys(Bzl)-Gly3-OH
32979-23-0

Z-Cys(Bzl)-Gly3-OH

Conditions
ConditionsYield
With sodium hydrogencarbonate In 1,4-dioxane for 24h; Ambient temperature;84%
glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

ethanol
64-17-5

ethanol

glycyl-glycyl-glycine ethyl ester hydrochloride
16194-06-2

glycyl-glycyl-glycine ethyl ester hydrochloride

Conditions
ConditionsYield
With thionyl chloride for 4h; Heating;83%
With hydrogenchloride for 72h;52.9%
glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

ethanol
64-17-5

ethanol

toluene-4-sulfonic acid
104-15-4

toluene-4-sulfonic acid

glycylglycylglycine ethyl ester p-toluenensulfonate

glycylglycylglycine ethyl ester p-toluenensulfonate

Conditions
ConditionsYield
In toluene for 96h; Heating;83%
for 4h; Heating;72.2%
glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

succinimidyl-S-benzoylthioglycolate
90236-37-6

succinimidyl-S-benzoylthioglycolate

benzoylmercaptoacetylglycylglycylglycine
103725-47-9

benzoylmercaptoacetylglycylglycylglycine

Conditions
ConditionsYield
With sodium hydroxide In acetonitrile at 20 - 60℃; for 6h;82%
With sodium hydroxide In water for 2.5h; Heating;
glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

(9H-fluoren-9-yl)methyl 1,2-dimethyl-2-((1-(3-oxo-3-(perfluorophenoxy)propyl)-1H-indol-2-yl)methyl)hydrazine-1-carboxylate
1610596-19-4

(9H-fluoren-9-yl)methyl 1,2-dimethyl-2-((1-(3-oxo-3-(perfluorophenoxy)propyl)-1H-indol-2-yl)methyl)hydrazine-1-carboxylate

2-(2-(2-(3-(2-((2-(((9H-fluoren-9-yl)methoxy)carbonyl)-1,2-dimethylhydrazinyl)methyl)-1H-indol-1-yl)propanamido)acetamido)acetamido)acetic acid

2-(2-(2-(3-(2-((2-(((9H-fluoren-9-yl)methoxy)carbonyl)-1,2-dimethylhydrazinyl)methyl)-1H-indol-1-yl)propanamido)acetamido)acetamido)acetic acid

Conditions
ConditionsYield
With sodium hydrogencarbonate In N,N-dimethyl acetamide; water; acetonitrile at 20℃; for 22h;82%
glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

[(morpholinyl)(thiocarbonyl)]benzimidoyl chloride
82655-60-5

[(morpholinyl)(thiocarbonyl)]benzimidoyl chloride

C18H22N5O5S(1-)*K(1+)

C18H22N5O5S(1-)*K(1+)

Conditions
ConditionsYield
With potassium hydroxide In ethanol at 20℃; for 8h;82%
glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

triphenyltin chloride
639-58-7

triphenyltin chloride

(C6H5)2Sn[H2NCH2C(O)NHCH2C(O)NCH2C(O)O]*CH3OH

(C6H5)2Sn[H2NCH2C(O)NHCH2C(O)NCH2C(O)O]*CH3OH

Conditions
ConditionsYield
With sodium; methanol In methanol byproducts: NaCl; N2; dissolving sodium in dry methanol, addn. of this soln. to methanolicsoln. of triglycine, refluxing with stirring for 3-4 h, addn. of methan olic soln. of triphenyltin(IV) chloride, refluxing with stirring for 6-7h; filtration of the centrifuged mixt., solvent removal under reduced pressure, trituration with hexane or petroleum ether, recrystn. from methanol-hexane or methanol-petroleum ether; elem. anal.;80%
tetrahydrofuran
109-99-9

tetrahydrofuran

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

[MoCl(η3-methylallyl)(CO)2(κ2(N,O)-pyridine-2-carboxaldehyde)]
951212-15-0

[MoCl(η3-methylallyl)(CO)2(κ2(N,O)-pyridine-2-carboxaldehyde)]

[MoCl(η3-methallyl)(CO)2(NC5H4-2-C(H)=NCH2CONHCH2CONHCH2COOH)]*THF
1359977-81-3

[MoCl(η3-methallyl)(CO)2(NC5H4-2-C(H)=NCH2CONHCH2CONHCH2COOH)]*THF

Conditions
ConditionsYield
In tetrahydrofuran; methanol (N2); Schlenk technique; mixt. of Mo complex and peptide in THF/MeOH wasrefluxed for 7 h; evapd. (vac.); washed (CH2Cl2); extd. (THF); filtered through kieselguhr; hexane slowly diffused into concd. THF soln. at -20°C; elem. anal.;78%
glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

succinoyl dichloride
543-20-4

succinoyl dichloride

succinyl bis
103499-98-5

succinyl bis

Conditions
ConditionsYield
With sodium hydroxide In acetone for 0.5h;77%
glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

toluene-4-sulfonic acid
104-15-4

toluene-4-sulfonic acid

benzyl alcohol
100-51-6

benzyl alcohol

triglycine benzyl ester toluenesulfonic acid salt

triglycine benzyl ester toluenesulfonic acid salt

Conditions
ConditionsYield
In toluene Heating;77%
In toluene for 8h; Heating;77%
potassium tetrachloroplatinate(II)
10025-99-7

potassium tetrachloroplatinate(II)

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

cis-dichloro-bis(glycylglycylclycine)platinum(II)
222528-78-1

cis-dichloro-bis(glycylglycylclycine)platinum(II)

Conditions
ConditionsYield
In potassium hydroxide Gly-Gly-Gly and K2PtCl4 stirred in aq. KOH for 3 d at room temp.; evapd.in vac.; dissolved in aq. HCl; evapd.; dissolved in DMF and filtered; a dded dropwise to acetone/Et2O; repeated pptn. from DMF/acetone with Et2O; centrifuged; washed with Et2O; dried over P2O5 in vac.; elem. anal.;77%
methanol
67-56-1

methanol

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

methyl 2-(2-(2-aminoacetamido)acetamido)acetate hydrochloride
39692-67-6

methyl 2-(2-(2-aminoacetamido)acetamido)acetate hydrochloride

Conditions
ConditionsYield
With hydrogenchloride for 3h; Heating;76%
With hydrogenchloride
dichloro(benzene)ruthenium(II) dimer
37366-09-9

dichloro(benzene)ruthenium(II) dimer

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

{(η6-C6H6)Ru(NH2CH2CONCH2CONHCH2CO2H)Cl}
128092-00-2

{(η6-C6H6)Ru(NH2CH2CONCH2CONHCH2CO2H)Cl}

Conditions
ConditionsYield
In water dissolving Ru-compd. in water by heating, filtration, addn of triglycine; redn. of vol. to 1 ml, crystn. by addn. of methanol and cooling to o°C; elem. anal.;76%
glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

(2-ethoxy-ethylsulfanyl)-acetic acid 2,5-dioxo-pyrrolidin-1-yl ester

(2-ethoxy-ethylsulfanyl)-acetic acid 2,5-dioxo-pyrrolidin-1-yl ester

(2-{2-[2-(2-ethoxy-ethylsulfanyl)-acetylamino]-acetylamino}-acetylamino)-acetic acid

(2-{2-[2-(2-ethoxy-ethylsulfanyl)-acetylamino]-acetylamino}-acetylamino)-acetic acid

Conditions
ConditionsYield
With sodium hydrogencarbonate In water; acetonitrile75.4%
glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

4-uulfamoyl-benzoic acid 2,5-dioxo-pyrrolidin-1-yl ester
154715-61-4

4-uulfamoyl-benzoic acid 2,5-dioxo-pyrrolidin-1-yl ester

1-<((glycylglycyl)glycyl)carbonyl>-4-sulfamoylbenzene
165682-40-6

1-<((glycylglycyl)glycyl)carbonyl>-4-sulfamoylbenzene

Conditions
ConditionsYield
With potassium dihydrogenphosphate In acetone for 2h; Ambient temperature;75%
In acetone at 20℃; for 2h; pH=7.0 - 7.5;
glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

di(n-butyl)tin oxide
818-08-6

di(n-butyl)tin oxide

(C4H9)2Sn[H2NCH2C(O)NHCH2C(O)NCH2C(O)O]

(C4H9)2Sn[H2NCH2C(O)NHCH2C(O)NCH2C(O)O]

Conditions
ConditionsYield
In methanol N2; dropwise addn. of a dry hot methanolic soln. of tin compd. to hot methanolic soln. of triglycine (1:1 mol. ratio), refluxing with stirring for 14-16 h with azeotropic removal of water; filtration, solvent removal under reduced pressure, crystn. by trituration with hexane, recrystn. from methanol-hexane; elem. anal.;75%
tetrahydrofuran
109-99-9

tetrahydrofuran

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

[ReBr(CO)3(pyridine-2-carboxaldehyde)]

[ReBr(CO)3(pyridine-2-carboxaldehyde)]

fac-[ReBr(CO)3(NC5H4-2-C(H)=NCH2CONHCH2CONHCH2COOH)]*THF

fac-[ReBr(CO)3(NC5H4-2-C(H)=NCH2CONHCH2CONHCH2COOH)]*THF

Conditions
ConditionsYield
In ethanol (N2); Schlenk technique; mixt. of Re complex and peptide in EtOH was refluxed for 2 h; evapd. (vac.); washed (hexane, CH2Cl2/hexane, 1/1); dissolved in THF; filtered through kieselguhr; hexane added; evapd. (vac.); elem. anal.;75%
tetrahydrofuran
109-99-9

tetrahydrofuran

glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

[MnBr(CO)3(pyridine-2-carboxaldehyde)]

[MnBr(CO)3(pyridine-2-carboxaldehyde)]

fac-[MnBr(CO)3(NC5H4-2-C(H)=NCH2CONHCH2CONHCH2COOH)]*THF

fac-[MnBr(CO)3(NC5H4-2-C(H)=NCH2CONHCH2CONHCH2COOH)]*THF

Conditions
ConditionsYield
In ethanol (N2); Schlenk technique; mixt. of Mn complex and peptide in EtOH was refluxed for 9 h; evapd. (vac.); washed (hexane, CH2Cl2/hexane, 1/1); dissolved in THF/MeOH; filtered through kieselguhr; hexane added; evapd. (vac.); elem. anal.;73%
glycine-glycine-glycine
556-33-2

glycine-glycine-glycine

Methacryloyl chloride
920-46-7

Methacryloyl chloride

N-Methacryloyldiglycylglycin
61435-67-4

N-Methacryloyldiglycylglycin

Conditions
ConditionsYield
Stage #1: glycine-glycine-glycine With sodium hydroxide In water at 0 - 5℃; pH=9 - 10.5; ice salt bath;
Stage #2: Methacryloyl chloride In water at 0 - 20℃; pH=9 - 10.5;
Stage #3: With nitric acid In water
73%

Glycyl-glycyl-glycine Specification

The Glycine, glycylglycyl-, with CAS registry number 556-33-2, belongs to the following product categories: (1)Biochemistry; (2)Oligopeptides; (3)Peptide Synthesis. It has the systematic name of glycylglycylglycine. This chemical is a kind of white crystalline powder. And it should be stored at the temperature of 2-8°C. What's more, its EINECS is 209-122-0.

Physical properties of Glycine, glycylglycyl-: (1)ACD/LogP: -2.04; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): -4.53; (4)ACD/LogD (pH 7.4): -5.02; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 7; (10)#H bond donors: 5; (11)#Freely Rotating Bonds: 6; (12)Polar Surface Area: 70.16 Å2; (13)Index of Refraction: 1.524; (14)Molar Refractivity: 42.19 cm3; (15)Molar Volume: 137.7 cm3; (16)Polarizability: 16.72×10-24cm3; (17)Surface Tension: 62.7 dyne/cm; (18)Density: 1.373 g/cm3; (19)Flash Point: 340.1 °C; (20)Enthalpy of Vaporization: 102.93 kJ/mol; (21)Boiling Point: 638.8 °C at 760 mmHg; (22)Vapour Pressure: 5.82E-18 mmHg at 25°C.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(NCC(=O)O)CNC(=O)CN
(2)InChI: InChI=1/C6H11N3O4/c7-1-4(10)8-2-5(11)9-3-6(12)13/h1-3,7H2,(H,8,10)(H,9,11)(H,12,13)
(3)InChIKey: XKUKSGPZAADMRA-UHFFFAOYAU
(4)Std. InChI: InChI=1S/C6H11N3O4/c7-1-4(10)8-2-5(11)9-3-6(12)13/h1-3,7H2,(H,8,10)(H,9,11)(H,12,13)
(5)Std. InChIKey: XKUKSGPZAADMRA-UHFFFAOYSA-N

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