Molecular structure of Hydroxychloroquine sulfate (CAS NO.747-36-4) is:
Product Name: Hydroxychloroquine sulfate
CAS Registry Number: 747-36-4
IUPAC Name: 2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol ; sulfuric acid
Molecular Weight: 433.95002 [g/mol]
Molecular Formula: C18H26ClN3O.H2SO4
H-Bond Donor: 4
H-Bond Acceptor: 8
EINECS: 212-019-3
Melting Point: 240 °C
Water Solubility: Freely Soluble
Flash Point: 266.3 °C
Enthalpy of Vaporization: 83.05 kJ/mol
Boiling Point: 516.7 °C at 760 mmHg
Vapour Pressure: 1.68E-11 mmHg at 25 °C
Product Categories: Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Hydroxychloroquine sulfate (CAS NO.747-36-4) can be used as an antimalarial, antirheumatic, lupus erythematosus suppressant.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
child | LDLo | oral | 600mg/kg (600mg/kg) | BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES CARDIAC: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA | Journal of Analytical Toxicology. Vol. 14, Pg. 186, 1990. |
women | TDLo | oral | 400mg/kg (400mg/kg) | CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION | Journal of Toxicology, Clinical Toxicology. Vol. 37, Pg. 861, 1999. |
Safty information about Hydroxychloroquine sulfate (CAS NO.747-36-4) is:
Hazard Codes: Xn,Xi
Risk Statements: 42/43-36/37/38-36-22
R42/43:May cause sensitization by inhalation and skin contact.
R36/37/38:Irritating to eyes, respiratory system and skin.
R36:Irritating to eyes.
R22:Harmful if swallowed.
Safety Statements: 37/39-26
S37/39:Wear suitable gloves and eye/face protection.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
RTECS: KK3342500
Hydroxychloroquine sulfate , its cas register number is 747-36-4. It also can be called (+-)-2-((4-((7-Chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol sulfate (1:1) (salt) ; 2-((4-((7-Chloro-4-quinolinyl)amino)pentyl)ethylamino)ethanol sulfate (1:1) (salt) ; 2-((4-((7-Chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol sulfate (1:1) (salt) ; Ercoquin ; Ethanol, 2-((4-((7-chloro-4-quinolinyl)amino)pentyl)ethyl)amino-, (+-)-, sulfate (1:1) salt ; Ethanol, 2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)-, sulfate (1:1) (salt) ; Plaquenil ; Plaquinol ; Toremonil .It is a odorless off-white solid.
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