-
Name
Iron-dextran
- EINECS 202-785-7
- CAS No. 9004-66-4
- Density
- Solubility
- Melting Point
- Formula FeH2O4S
- Boiling Point
- Molecular Weight 1347.3642
- Flash Point
- Transport Information
- Appearance Dark reddish-brown liquid
- Safety 23-26-36/37/39-45-36
- Risk Codes 40-42/43
-
Molecular Structure
-
Hazard Symbols
Xn
- Synonyms Imferon (8CI);A100;B 75;B 75 (pharmaceutical);Chinofer;Dexfer;Dexferrum;Dextran iron complex;Dextrofer 100;Dextrofer 75;Fe-dextran;Fenate;Ferdex 100;Ferranimal 75;Ferranimal 75M;Ferric dextran;Ferridextran;Ferrodextran;Ferroglucin;Ferroglukin 75;Hyferdex;INFeD;Idofer;Impheron;Imposil;Iro-jex;Iron dextran injection;Iron-GARD;Iron-dextran complex;Ironorm;Kemofei;Myofer 100;Nonemic;Polyfer;Proferedex;Prolongal;SHU 555;Iron-dextran;
- PSA 0.00000
- LogP 0.00000
Iron-dextran Consensus Reports
Iron-dextran Specification
The Iron-dextran complex is a complex of ferric oxyhydroxide with dextrans of 5000 to 7000 daltons in a viscous solution containing 50 mg/ml of iron. With the CAS registry number 9004-66-4, it is also named as Ferric dextran. The classification codes are Drug / Therapeutic Agent; Hematinic; Hematinics; Hematologic Agents; Human Data; Reproductive Effect; Tumor data. It is dark reddish-brown liquid which is soluble in hot water, soluble in ethanol and other organic solvents. Additionally, Iron-dextran is combustible, unstable at a pH of 5 and decomposes at 149-158° F. It may be sensitive to prolonged exposure to air. The symptoms associated with exposure to Iron-dextran are headaches, vomiting, and dizziness. When not being used, product containers should be kept sealed and stored in a cool, dry place.
Uses of Iron-dextran complex: It is supplied as a parenteral preparation and is used as a hematinic. Furthermore, it used for the prevention and treatment of iron deficiency anemia of Pigs and other livestock, promoting growth and development.
When you are using this chemical, please be cautious about it as the following:
It may cause sensitization by inhalation and skin contact, so people should not breathe vapour. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
The following are the toxicity data which has been tested.
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD | intramuscular | > 450mg(Fe)/kg (450mg/kg) | British Journal of Pharmacology and Chemotherapy. Vol. 10, Pg. 375, 1955. | |
| mouse | LD50 | intravenous | 460mg(Fe)/kg (460mg/kg) | Acta Poloniae Pharmaceutica. For English translation, see APPFAR. Vol. 18, Pg. 149, 1961. | |
| mouse | LD50 | oral | 1gm(Fe)/kg (1000mg/kg) | British Journal of Pharmacology and Chemotherapy. Vol. 24, Pg. 352, 1965. | |
| rabbit | LD | intramuscular | > 690mg(Fe)/kg (690mg/kg) | British Journal of Pharmacology and Chemotherapy. Vol. 10, Pg. 375, 1955. | |
| rabbit | LDLo | intravenous | 500mg(Fe)/kg (500mg/kg) | British Journal of Pharmacology and Chemotherapy. Vol. 10, Pg. 375, 1955. | |
| rat | LD50 | intraperitoneal | 3gm(Fe)/kg (3000mg/kg) | Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971. | |
| rat | LDLo | intramuscular | 1617mg(Fe)/kg (1617mg/kg) | Acta Veterinaria Vol. 29, Pg. 21, 1979. |
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