Conditions | Yield |
---|---|
With marine microbial esterase In aq. phosphate buffer at 37℃; for 1h; pH=7.5; pH-value; Temperature; Solvent; Reagent/catalyst; Time; Resolution of racemate; Enzymatic reaction; enantioselective reaction; | A n/a B 98% |
With water; Candida rugosa lipase In aq. phosphate buffer at 45℃; for 8h; pH=7.2; Enzymatic reaction; enantioselective reaction; | A n/a B n/a |
Conditions | Yield |
---|---|
With Candida utilis NBRC0988 Cupdc1Δ4-LDH2 mutant at 35℃; for 33h; Microbiological reaction; | 95.1% |
bei der Vergaerung durch Streptococcus lactis unter verschiedenen Bedingungen; | |
With Sn-beta catalyst In water at 200℃; under 30003 Torr; for 0.5h; Catalytic behavior; Solvent; Inert atmosphere; Autoclave; Green chemistry; |
Conditions | Yield |
---|---|
With C11H19AlN2 In dichloromethane at 20℃; for 24h; Reagent/catalyst; Schlenk technique; | A n/a B 89% |
(S)-Methyl lactate
L-Lactic acid
Conditions | Yield |
---|---|
With lithium hydroxide monohydrate In tetrahydrofuran; water at 0 - 20℃; for 48h; Inert atmosphere; | 80% |
With lithium hydroxide In methanol at 20℃; | |
With water at 100℃; for 6h; Product distribution / selectivity; | |
With water; Amberlyst-36 at 100℃; for 1h; | |
With water at 100℃; for 1h; | 7 g |
L-Lactic acid
Conditions | Yield |
---|---|
With hydrogenchloride In 1,4-dioxane for 3h; Heating; | 73% |
methanol
(2S)-2-(hydroxymethyl)-1-[(2R)-2-hydroxypropanoyl]pyrrolidine
L-Lactic acid
Conditions | Yield |
---|---|
With sulfuric acid Heating; | 71% |
Conditions | Yield |
---|---|
With sulfuric acid; sodium nitrite In water at 0℃; for 12h; | 65% |
With tert.-butylnitrite In 1,4-dioxane; water at 20℃; for 1h; Inert atmosphere; | 58% |
bei der Einw. von Oidium lactis; |
carbon dioxide
acetaldehyde
A
L-Lactic acid
B
2-oxo-propionic acid
Conditions | Yield |
---|---|
With pyruvate decarboxylase; thiamine pyrophosphate; L-lactic dehydrogenase; 1,4-dihydronicotinamide adenine dinucleotide for 1h; pH=9.5; Enzymatic reaction; | A 51% B 14% |
With pyruvate decarboxylase; thiamine pyrophosphate; L-lactic dehydrogenase; 1,4-dihydronicotinamide adenine dinucleotide for 1h; pH=10.5; Enzymatic reaction; | A 27% B 28% |
Conditions | Yield |
---|---|
With Fructose 1,6-bisphosphate; piperazine*HCl buffer; sodium formate; nicotinamide adenine dinucleotide; diothiothreitol pH 6.0, lyophilized formate dehydrogenase, lactate dehydrogenase from Bacillus stearothermophilus (BSLDH Q102R/C97G); | 45% |
With lipoamide; DTTox; NAD; xanthin; PAN gel Electrochemically, Enzymatic, 3.5 d; Multistep reaction; |
ethyl 2-hydroxypropionate
A
L-Lactic acid
B
D-Lactic acid
C
(R)-Ethyl lactate
Conditions | Yield |
---|---|
With ammonium hydroxide at 30℃; pH=6.9; | A n/a B n/a C 34.5% |
D-glucose
A
formic acid
B
glycolic Acid
C
L-Lactic acid
D
malonic acid
E
succinic acid
F
oxalic acid
G
acetic acid
H
propionic acid
I
2-oxo-propionic acid
J
maleic acid
Conditions | Yield |
---|---|
With sodium silicate; water at 300℃; under 64356.4 Torr; for 0.0166667h; Reagent/catalyst; Sealed tube; | A n/a B n/a C 30% D n/a E n/a F n/a G n/a H n/a I n/a J n/a |
D-glucose
A
5-hydroxymethyl-2-furfuraldehyde
B
formic acid
C
L-Lactic acid
D
succinic acid
E
oxalic acid
F
acetic acid
G
propionic acid
H
2-oxo-propionic acid
I
maleic acid
Conditions | Yield |
---|---|
With water at 300℃; under 64356.4 Torr; for 0.0166667h; Reagent/catalyst; Sealed tube; | A n/a B n/a C 30% D n/a E n/a F n/a G n/a H n/a I n/a |
citric acid
A
Oxalacetic acid
B
L-Lactic acid
C
D-Lactic acid
D
3-hydroxy-2-butanon
E
acetic acid
F
2-oxo-propionic acid
Conditions | Yield |
---|---|
With Leuconostoc mesenteroides at 30℃; for 1h; potassium phosphate buffer, pH 5.0; other conditions also investigated; several substrates investigated; | A 0.66% B 0.06% C 1.77% D 6.86% E 15.5% F 0.05% |
citric acid
A
Oxalacetic acid
B
L-Lactic acid
C
D-Lactic acid
D
acetic acid
E
2-oxo-propionic acid
F
dimethylglyoxal
Conditions | Yield |
---|---|
With Leuconostoc mesenteroides at 30℃; for 1h; potassium phosphate buffer, pH 5.0; other conditions also investigated; several substrates investigated; | A 0.66% B 0.06% C 1.77% D 15.5% E 0.05% F 1.72% |
Conditions | Yield |
---|---|
bei der Einw. von Oidium lactis; | |
With cis-nitrous acid |
Conditions | Yield |
---|---|
bei der Einw. von Oidium lactis; |
LACTIC ACID
L-Lactic acid
Conditions | Yield |
---|---|
durch Spaltung mit Morphin; | |
mit Hilfe von Strychnin; | |
mit Hilfe von Chinin; | |
mit Hilfe von Morphin; |
(S)-2-bromopropanoic acid
L-Lactic acid
Conditions | Yield |
---|---|
With water; silver carbonate |
R-(+)-2-bromopropionic acid
L-Lactic acid
Conditions | Yield |
---|---|
With potassium hydroxide |
Conditions | Yield |
---|---|
durch Einw. roter Blutkoerperchen; |
Conditions | Yield |
---|---|
bei der Einwirkung von Bacterium coli commune; |
L-arabinose
glucose
L-Lactic acid
Conditions | Yield |
---|---|
durch Einw. von Propionsaeurebakterien; |
Conditions | Yield |
---|---|
bei der Einw. von Bact. coli; |
Conditions | Yield |
---|---|
beim Abbau durch Faeulnis-Bakterien; |
Conditions | Yield |
---|---|
bei der Vergaerung durch Lactobacillus Nr.S 48a, 3; | |
bei der Vergaerung durch Lactobacillus Nr.S 48a,3; |
Conditions | Yield |
---|---|
Bacillus paralacticus erzeugt; |
glucose
A
LACTIC ACID
B
L-Lactic acid
Conditions | Yield |
---|---|
With carbon monoxide bei der Einw. von Cl.butylicum; | |
With hydrogen cyanide bei der Einw. von Cl.butylicum; |
glucose
L-Lactic acid
Conditions | Yield |
---|---|
With caseinhydrolysate Geschwindigkeit der Bildung durch St.aureus; | |
durch haemolytische Streptokokken und durch Pneumokokken; | |
durch Streptococcus thermophilus; |
Conditions | Yield |
---|---|
With GLUTATHIONE; toluene durch Colibakterien; |
Conditions | Yield |
---|---|
durch Einw. roter Blutkoerperchen; |
L-Lactic acid
Conditions | Yield |
---|---|
In ethanol at 20℃; for 1h; | 100% |
L-Lactic acid
Conditions | Yield |
---|---|
In ethanol at 20℃; for 2h; | 100% |
L-Lactic acid
Conditions | Yield |
---|---|
With 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 0 - 20℃; | 100% |
L-Lactic acid
1,3-dibutyl-5,6-dimethylbenzimidazolium iodide
C3H5O3(1-)*C17H27N2(1+)
Conditions | Yield |
---|---|
Stage #1: L-Lactic acid With Amberlyst A-26 (OH- form) In methanol; water at 20℃; Stage #2: 1,3-dibutyl-5,6-dimethylbenzimidazolium iodide In methanol | 100% |
L-Lactic acid
1-butyl-4-methylpyridin-1-ium iodide
1-butyl-4-methylpyridinium lactate
Conditions | Yield |
---|---|
Stage #1: L-Lactic acid With Amberlyst A-26 (OH- form) In methanol; water at 20℃; Stage #2: 1-butyl-4-methylpyridin-1-ium iodide In methanol | 100% |
L-Lactic acid
choline iodide
2-hydroxyethyl-trimethylammonium L-Lactate
Conditions | Yield |
---|---|
Stage #1: L-Lactic acid With Amberlyst A-26 (OH- form) In methanol; water at 20℃; Stage #2: choline iodide In methanol | 100% |
Conditions | Yield |
---|---|
Stage #1: L-Lactic acid With Amberlyst A-26 (OH- form) In methanol; water at 20℃; Stage #2: 1,3-dimethylimidazolim iodide In methanol | 100% |
L-Lactic acid
1-methyl-3-(n-butyl)imidazolium iodide
[bmim][(S)-lactate]
Conditions | Yield |
---|---|
Stage #1: L-Lactic acid With Amberlyst A-26 (OH- form) In methanol; water at 20℃; Stage #2: 1-methyl-3-(n-butyl)imidazolium iodide In methanol | 100% |
L-Lactic acid
1,3-bis(n-butyl)imidazolium iodide
C3H5O3(1-)*C11H21N2(1+)
Conditions | Yield |
---|---|
Stage #1: L-Lactic acid With Amberlyst A-26 (OH- form) In methanol; water at 20℃; Stage #2: 1,3-dibutyl-1,3-imidazolium iodide In methanol | 100% |
L-Lactic acid
1-butyl-2,3-dimethylimidazolium lactate
Conditions | Yield |
---|---|
Stage #1: L-Lactic acid With Amberlyst A-26 (OH- form) In methanol; water at 20℃; Stage #2: 1-butyl-2,3-dimethylimidazolium bromide In methanol | 100% |
Conditions | Yield |
---|---|
With pyridine; dmap In tetrahydrofuran at 80℃; for 24h; Inert atmosphere; | 100% |
Conditions | Yield |
---|---|
at 10 - 20℃; for 168h; | 99.5% |
Conditions | Yield |
---|---|
With ruthenium-carbon composite; hydrogen In water at 79.84℃; under 60006 Torr; for 4h; Catalytic behavior; Reagent/catalyst; Autoclave; Sealed tube; | 99% |
L-Lactic acid
Conditions | Yield |
---|---|
With pyridine; dmap In tetrahydrofuran at 60℃; for 72h; Temperature; | 99% |
Conditions | Yield |
---|---|
With pyridine; dmap In tetrahydrofuran at 80℃; for 24h; Inert atmosphere; | 99% |
L-Lactic acid
5,5-difluoro-10-mesityl-1,3,7,9-tetramethyl-5H-4λ4,5λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinine
Conditions | Yield |
---|---|
With chloro-trimethyl-silane In acetonitrile at 120℃; for 0.5h; Microwave irradiation; | 99% |
Conditions | Yield |
---|---|
With chloro-trimethyl-silane In acetonitrile at 120℃; for 7h; Microwave irradiation; | 99% |
L-Lactic acid
acetyl chloride
(S)-2-acetoxypropionic acid
Conditions | Yield |
---|---|
In tetrahydrofuran at 20℃; for 2h; | 98% |
With acetic acid at 0 - 20℃; | 92% |
With acetic acid | 90% |
L-Lactic acid
Conditions | Yield |
---|---|
Stage #1: (S)-7-amino-5-(2-benzyloxy-ethyl)-5H,7H-dibenzo[b,d]azepin-6-one; L-Lactic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 0 - 20℃; for 3.5h; Stage #2: With hydrogenchloride In water | 98% |
L-Lactic acid
cholin hydroxide
2-hydroxyethyl-trimethylammonium L-Lactate
Conditions | Yield |
---|---|
In methanol at 20℃; Cooling with ice; | 98% |
In ethanol at 20℃; for 1h; |
Conditions | Yield |
---|---|
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at -5 - 20℃; Inert atmosphere; | 98% |
L-Lactic acid
1,3-bis(mesityl)imidazolium chloride
C3H5O3(1-)*C21H25N2(1+)
Conditions | Yield |
---|---|
Stage #1: L-Lactic acid With Amberlyst A-26 (OH- form) In methanol; water at 20℃; Stage #2: 1,3-bis(mesityl)imidazolium chloride In methanol | 98% |
Conditions | Yield |
---|---|
In water at 100℃; for 24h; | 97% |
Conditions | Yield |
---|---|
With hydrogen In water at 119.84℃; under 60006 Torr; for 2h; Catalytic behavior; Reagent/catalyst; Autoclave; Sealed tube; | 97% |
Conditions | Yield |
---|---|
With silver hydroxide In water for 24h; | 96% |
Conditions | Yield |
---|---|
With cobalt(II) tetrafluoroborate hexahydrate; (p-anisyl)triphos; hydrogen In 1,4-dioxane at 140℃; under 15001.5 Torr; for 24h; Autoclave; Green chemistry; | 96% |
L-Lactic acid
2,3,4,5,6-pentamethylbenzyl chloride
L-lactic acid pentamethylbenzyl ester
Conditions | Yield |
---|---|
With TEA In N,N-dimethyl-formamide Ambient temperature; | 95% |
With TEA In N,N-dimethyl-formamide at 50℃; for 2h; Alkylation; | 63% |
Conditions | Yield |
---|---|
With pyridine In tetrahydrofuran for 3h; Ambient temperature; | 95% |
Reported in EPA TSCA Inventory.
The L(+)-Lactic acid, with the CAS registry number 79-33-4,is also known as Kerosine (petroleum), hydrodesulfurized. It belongs to the product categories of petrochemical industry. This chemical's molecular formula is C3H6O3 and molecular weight is 90.08.Its EINECS number is 201-196-2. What's more,Its systematic name is L(+)-Lactic acid. It is a Crystalline Solid which occurs in small quantities in the blood and muscle fluid of man and animals. The lactic acid concentration increases in muscle and blood after vigorous activity. L(+)-Lactic acid is also present in liver, kidney, thymus gland, human amniotic fluid.
Physical properties about L(+)-Lactic acid are:
(1)ACD/LogP: -0.85; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -2.92; (4)ACD/LogD (pH 7.4): -4.40; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 1.00; (8)ACD/KOC (pH 7.4): 1.00; (9)#H bond acceptors: 3; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 2; (12)Index of Refraction: 1.451; (13)Molar Refractivity: 19.006 cm3; (14)Molar Volume: 70.564 cm3; (15)Surface Tension: 49.7639999389648 dyne/cm; (16)Density: 1.277 g/cm3; (17)Flash Point: 109.936 °C; (18)Enthalpy of Vaporization: 53.96 kJ/mol; (19)Boiling Point: 227.561 °C at 760 mmHg; (20)Vapour Pressure: 0.0149999996647239 mmHg at 25°C.
You can still convert the following datas into molecular structure:
(1)SMILES:O=NOC(C)C;
(2)Std. InChI:InChI=1S/C3H7NO2/c1-3(2)6-4-5/h3H,1-2H3;
(3)Std. InChIKey:SKRDXYBATCVEMS-UHFFFAOYSA-N.
Safety Information of L(+)-Lactic acid:
The L(+)-Lactic acid is irritating to eyes, respiratory system and skin and risk of serious damage to the eyes. And it causes burns. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) .When you use it ,wear suitable protective clothing, gloves and eye/face protection. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
The toxicity data of L(+)-Lactic acid are as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 3194mg/kg (3194mg/kg) | Toxicology. Vol. 62, Pg. 203, 1990. |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View