Lanosta-8,24-dien-3-ol,(3beta)- supplier

Name
LANOSTEROL
EINECS 201-214-9
CAS No. 79-63-0
Article Data25
CAS DataBase
Density 0.988 g/cm³
Solubility
Melting Point 137 °C
Formula C₃₀H₅₀O
Boiling Point 498.855 °C at 760 mmHg
Molecular Weight 426.726
Flash Point 221.143 °C
Transport Information
Appearance
Safety
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms Lanosta-8,24-dien-3b-ol (8CI);Lanostadien-3b-ol (7CI);Lanosterol (6CI);3b-Hydroxylanosta-8,24-diene;4,4,14a-Trimethylcholesta-8,24-dien-3b-ol;5a-Lanosta-8,24-dien-3b-ol;Lanosta-8,24-dienol;Lanosterin;Lanster;NSC60677;
PSA 20.23000
LogP 8.47910

Synthetic route

: 2671-68-3
O-acetyl-lanosterol

: 79-63-0
tirucallol

Conditions

Conditions	Yield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In methanol for 72h; Ambient temperature;	94%
With potassium hydroxide In ethanol at 60℃; for 2h;
Multi-step reaction with 3 steps 1: SeO2 / aq. ethanol 2: NaBH4 / aq. ethanol 3: (i) SO3, Py, THF, (ii) LiAlH4 View Scheme

: 14050-42-1, 54910-48-4, 54910-49-5, 54910-50-8, 55058-26-9, 55058-27-0, 132199-42-9, 138809-21-9, 147731-51-9, 7200-26-2
2,3-Oxidosqualene

: 79-63-0
tirucallol

Conditions

Conditions	Yield
With Trypanosoma cruzi LHY4-[pBJ1.22] transformant at 25℃; for 24h;	82%
With K-phosphate buffer; Triton X-100 In water at 37℃; for 5h; oxidosqualene-lanosterol cyclase; effect of various detergents;
With Trypanosoma cruzi oxidosqualene cyclase; 3-(trimethylsilyl)-1-propanesulfonic acid,sodium salt In dimethylsulfoxide-d6; aq. phosphate buffer at 37℃; pH=7; Reagent/catalyst; Enzymatic reaction;

: 14050-42-1, 54910-48-4, 54910-49-5, 54910-50-8, 55058-26-9, 55058-27-0, 132199-42-9, 138809-21-9, 147731-51-9, 7200-26-2
2,3-Oxidosqualene

A: 514-45-4
parkeol

B: 79-63-0
tirucallol

C: 69637-82-7
Lanost-24-ene-3β,9α-diol

Conditions

Conditions	Yield
With S. cerevisiae lanosterol-synthase Thr 384 Tyr mutant Product distribution; Further Variations:; Reagents;	A 11% B 79% C 10%

...Expand

: 124770-75-8
Octanoic acid (3S,5R,10S,13R,14R,17R)-17-((R)-1,5-dimethyl-hex-4-enyl)-4,4,10,13,14-pentamethyl-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester

: 79-63-0
tirucallol

Conditions

Conditions	Yield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In methanol; benzene for 240h; Ambient temperature;	19%

: 57-88-5
cholesterol

: 79-63-0
tirucallol

Conditions

Conditions	Yield
ueber mehrere Stufen;

: 469-38-5
cycloartenol

A: 514-45-4
parkeol

B: 79-63-0
tirucallol

C: 110654-88-1
Cucurbita-5(10),24-dien-3β-ol

D: 23515-91-5
tirucalla-7,24-dien-3β-ol

Conditions

Conditions	Yield
With sulfuric acid In isopropyl alcohol at 80℃; for 12h; Further byproducts given;

...Expand

: 20905-52-6
3β-acetoxy-24ξ-hydroxylanost-8-ene

A: 79-62-9, 564-60-3, 6198-06-7, 6593-55-1, 13879-09-9, 39701-94-5, 59684-64-9, 78821-82-6
24,25-dihydrolanosterol

B: 79-63-0
tirucallol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride; trichlorophosphate 1.) pyridine, 5 h, reflux, 2.) dioxane, 10 h, reflux; Yield given. Multistep reaction. Yields of byproduct given;

: 68612-46-4
3β-acetoxy-(24E)-lanostadiene-8,24 ol-26

: 79-63-0
tirucallol

Conditions

Conditions	Yield
(i) SO3, Py, THF, (ii) LiAlH4; Multistep reaction;

: 14050-42-1, 54910-48-4, 54910-49-5, 54910-50-8, 55058-26-9, 55058-27-0, 132199-42-9, 138809-21-9, 147731-51-9, 7200-26-2
2,3-Oxidosqualene

A: 514-45-4
parkeol

B: 469-38-5
cycloartenol

C: 79-63-0
tirucallol

Conditions

Conditions	Yield
With CAS1Ile841Val mutant; YPG+heme rearrangement; cyclization;

...Expand

: 469-38-5
cycloartenol

A: 514-45-4
parkeol

B: 79-63-0
tirucallol

C: 110654-88-1
Cucurbita-5(10),24-dien-3β-ol

D: 35012-08-9
10α-cucurbita-5,24-diene-3β-ol

E: 23515-91-5
tirucalla-7,24-dien-3β-ol

F: 129763-89-9
5α-Lanosta-9(11),25-dien-3β-ol

G other alcohols, and dehydration products: other alcohols, and dehydration products

Conditions

Conditions	Yield
With sulfuric acid In isopropyl alcohol at 80℃; for 12h; Product distribution;

...Expand

: 14050-42-1, 54910-48-4, 54910-49-5, 54910-50-8, 55058-26-9, 55058-27-0, 132199-42-9, 138809-21-9, 147731-51-9, 7200-26-2
2,3-Oxidosqualene

A: 79-63-0
tirucallol

B: 125287-06-1
(-)-achilleol A

Conditions

Conditions	Yield
With S. cerevisiae lanosterol synthase Val454Gly mutant at 20℃; pH=6.2; Product distribution; Further Variations:; Reagents; Cyclization; Enzymatic reaction;

: 14050-42-1, 54910-48-4, 54910-49-5, 54910-50-8, 55058-26-9, 55058-27-0, 132199-42-9, 138809-21-9, 147731-51-9, 7200-26-2
2,3-Oxidosqualene

A: 514-45-4
parkeol

B: 79-63-0
tirucallol

C: 125287-06-1
(-)-achilleol A

D: achilleol C

Conditions

Conditions	Yield
With Arabidopsis thaliana cycloartenol synthase Ile481Gly; Triton X-100 In phosphate buffer for 24h; pH=6.4; Product distribution; Further Variations:; Reagents; Cyclization; Enzymatic reaction;

...Expand

: 54910-48-4
squalene 2,3(S)-oxide

A: 79-63-0
tirucallol

B: 125287-06-1
(-)-achilleol A

C: 9β-lanosta-7,24-dien-3β-ol

Conditions

Conditions	Yield
With cycloartenol synthase AtCAS1 Tyr410Cys mutant Product distribution; Further Variations:; Reagents;

...Expand

: 147731-51-9
2,3-oxidosqualene

: 79-63-0
tirucallol

Conditions

Conditions	Yield
With baker's yeast Saccharomyces cerevisiae on calcium alginate In diethyl ether at 30℃; for 20h; pH=7.4; Enzymatic reaction;

: 14050-42-1, 54910-48-4, 54910-49-5, 54910-50-8, 55058-26-9, 55058-27-0, 132199-42-9, 138809-21-9, 147731-51-9, 7200-26-2
2,3-Oxidosqualene

A: (13αH)-isomalabarica-14(26),17E,21-trien-3β-ol

B: 514-45-4
parkeol

C: 79-63-0
tirucallol

D: 125287-06-1
(-)-achilleol A

Conditions

Conditions	Yield
With lanosterol synthase mutant SceErg7 Tyr510His In water at 20℃; for 24h; pH=6.2; Product distribution; Further Variations:; Reagents;

...Expand

: 54910-48-4
squalene 2,3(S)-oxide

A: 514-45-4
parkeol

B: 469-38-5
cycloartenol

C: 79-63-0
tirucallol

Conditions

Conditions	Yield
With cycloartenol synthase I481V mutant In phosphate buffer at 20℃; for 24h; pH=7.4; Product distribution; Further Variations:; Reagents;

...Expand

: 63976-67-0, 63976-68-1, 20905-61-7
24(R,S)-3β-acetoxy-24,25-dihydroxy-5α-lanost-8-ene

: 79-63-0
tirucallol

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: CH2Cl2 / 2.5 h / Heating 2: 8.3 g / Ac2O / 3.5 h / 130 °C 3: KOH / ethanol / 2 h / 60 °C View Scheme

: Acetic acid (3S,5R,10S,13R,14R,17R)-17-[(R)-3-(2-dimethylamino-5,5-dimethyl-[1,3]dioxolan-4-yl)-1-methyl-propyl]-4,4,10,13,14-pentamethyl-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester

: 79-63-0
tirucallol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 8.3 g / Ac2O / 3.5 h / 130 °C 2: KOH / ethanol / 2 h / 60 °C View Scheme

: 13553-26-9
3β-acetoxy-lanost-8-en-24-one

: 79-63-0
tirucallol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 0.25 g / NaBH4 / tetrahydrofuran / 96 h / Ambient temperature 2: 1.) POCl3, 2.) LiAlH4 / 1.) pyridine, 5 h, reflux, 2.) dioxane, 10 h, reflux View Scheme

: 68612-49-7
3β-acetoxy-(24E)-lanosta-8,24-dien-26-al

: 79-63-0
tirucallol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: NaBH4 / aq. ethanol 2: (i) SO3, Py, THF, (ii) LiAlH4 View Scheme

: 54910-48-4
squalene 2,3(S)-oxide

A: 1073543-01-7
(9R,10S)-polypoda-8(26),13E,17E,21-tetraen-3β-ol

B: 514-45-4
parkeol

C: 79-63-0
tirucallol

Conditions

Conditions	Yield
With Saccharomyces cerevisiae oxidosqualene-lanosterol cyclaseY707Q Enzymatic reaction;

...Expand

: 54910-48-4
squalene 2,3(S)-oxide

A: 1073543-01-7
(9R,10S)-polypoda-8(26),13E,17E,21-tetraen-3β-ol

B: 514-45-4
parkeol

C: 79-63-0
tirucallol

D: 9β-lanosta-7,24-dien-3β-ol

Conditions

Conditions	Yield
With Saccharomyces cerevisiae oxidosqualene-lanosterol cyclaseY707H Enzymatic reaction;

...Expand

: 54910-48-4
squalene 2,3(S)-oxide

A: 514-45-4
parkeol

B: 79-63-0
tirucallol

C: 9β-lanosta-7,24-dien-3β-ol

Conditions

Conditions	Yield
With Saccharomyces cerevisiae oxidosqualene-lanosterol cyclaseY707F Enzymatic reaction;

...Expand

: 54910-48-4
squalene 2,3(S)-oxide

: 79-63-0
tirucallol

Conditions

Conditions	Yield
With Saccharomyces cerevisiae oxidosqualene-lanosterol cyclaseY707V Enzymatic reaction;
With Saccharomyces cerevisiae TKW14 expressing ERG7(Y99V) mutant Microbiological reaction;
With Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase ERG7(Phe699Leu) mutant
With Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase ERG7C7O3D Reagent/catalyst; Enzymatic reaction;

: 54910-48-4
squalene 2,3(S)-oxide

A: 79-63-0
tirucallol

B: 9β-lanosta-7,24-dien-3β-ol

Conditions

Conditions	Yield
With Saccharomyces cerevisiae oxidosqualene-lanosterol cyclaseY707I Enzymatic reaction;

: 54910-48-4
squalene 2,3(S)-oxide

A: 1203607-72-0
(13αH)-isomalabarica-14Z,17E,21-trien-3β-ol

B: 1203607-73-1
(13αH)-isomalabarica-14E,17E,21-trien-3β-ol

C: 79-63-0
tirucallol

Conditions

Conditions	Yield
With Saccharomyces cerevisiae TKW14 expressing ERG7(Y99A) mutant Microbiological reaction;
With Saccharomyces cerevisiae TKW14 expressing ERG7(Y99I) mutant Microbiological reaction;

...Expand

: 54910-48-4
squalene 2,3(S)-oxide

A: 1203607-72-0
(13αH)-isomalabarica-14Z,17E,21-trien-3β-ol

B: 79-63-0
tirucallol

Conditions

Conditions	Yield
With Saccharomyces cerevisiae TKW14 expressing ERG7(Y99E) mutant Microbiological reaction;

: 54910-48-4
squalene 2,3(S)-oxide

A: protosta-13(17)-dien-3β-ol

B: (17Z)-protosta-17(20),24-dien-3β-ol

C: 79-63-0
tirucallol

Conditions

Conditions	Yield
With Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase ERG7(Phe699His) mutant

...Expand

: 54910-48-4
squalene 2,3(S)-oxide

A: 514-45-4
parkeol

B: 79-63-0
tirucallol

Conditions

Conditions	Yield
With Aspergillus fumigatus oxidosqualene:protostadienol cyclase 702NKSCAIS708 mutant at 30℃; for 1h; Kinetics; Enzymatic reaction;

: 13879-13-5, 54325-09-6, 5539-04-8
lanosta-8,24-dien-3-one

A: 79-63-0
tirucallol

B: 76582-59-7
lanosta-8,24-dien-3α-ol

Conditions

Conditions	Yield
With potassium hydroxide In ethylene glycol for 5h; Reflux; optical yield given as %de;
With C36H103AlO4Si14; isopropyl alcohol In neat (no solvent) at 70℃; for 24h; Meerwein-Ponndorf-Verley Reduction; Glovebox; Schlenk technique;	A n/a B n/a

: 79-63-0
tirucallol

: 79-62-9, 564-60-3, 6198-06-7, 6593-55-1, 13879-09-9, 39701-94-5, 59684-64-9, 78821-82-6
24,25-dihydrolanosterol

Conditions

Conditions	Yield
With 5%-palladium/activated carbon; hydrogen In dichloromethane at 20℃; under 2585.81 Torr; for 24h;	100%
With ammonium formate; palladium on activated charcoal In dichloromethane for 7h; Irradiation;	80%
With hydrogen; platinum(IV) oxide
With hydrogen; palladium on activated charcoal In ethyl acetate; toluene at 20℃; for 17h;
With palladium on activated charcoal; hydrogen In ethyl acetate; phenol at 20℃;

: 79-63-0
tirucallol

: 407-25-0
trifluoroacetic anhydride

: 10112-12-6
Lanosterin-trifluoracetat

Conditions

Conditions	Yield
With pyridine; dmap In dichloromethane at 0℃; for 0.333333h;	100%

: 110-87-2
3,4-dihydro-2H-pyran

: 79-63-0
tirucallol

: 84882-57-5, 144407-65-8
3β-Tetrahydropyranyl lanosterol

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In dichloromethane	100%
With pyridinium p-toluenesulfonate In dichloromethane for 5h; Ambient temperature; Yield given;

: 79-63-0
tirucallol

: 108-24-7
acetic anhydride

: 2671-68-3
O-acetyl-lanosterol

Conditions

Conditions	Yield
With pyridine at 20℃;	100%
With pyridine at 20℃; for 12h;	84%
With pyridine at 20℃; for 12h;	84%

: 79-63-0
tirucallol

: 106065-41-2
2,8,24-lanostatriene

Conditions

Conditions	Yield
With sodium tosylate; thiamine diphosphate; diethylazodicarboxylate In tetrahydrofuran for 1.25h; Heating;	95%
With 5%-palladium/activated carbon; hydrogen In ethyl acetate; benzene at 20℃; Inert atmosphere;

: 79-63-0
tirucallol

: 68-12-2, 33513-42-7
N,N-dimethyl-formamide

: 115045-75-5
lanosta-8,24-dien-3β-yl formate

Conditions

Conditions	Yield
With diphenylphosphinopolystyrene; iodine In dichloromethane at 50℃; for 2h;	92%
With trichlorophosphate at 5 - 20℃; for 4h;	91%

: 79-63-0
tirucallol

: 98-09-9
benzenesulfonyl chloride

: lanost-8-en-3β-yl benzenesulfonate

Conditions

Conditions	Yield
With pyridine at 0℃; for 72h;	91%

: 79-63-0
tirucallol

: 88165-78-0, 107242-94-4
(3S,5R,10S,13R,14R,17R)-3-methoxy-4,4,10,13,14-pentamethyl-17-((R)-6-methylhept-5-en-2-yl)-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene

Conditions

Conditions	Yield
With sodium hydride; methyl iodide In tetrahydrofuran at 20℃; for 12h;	90%

: 79-63-0
tirucallol

: 220769-88-0
4,5-dichloroisothiazole-3-carboxylic acid chloride

: 4,5-Dichloro-isothiazole-3-carboxylic acid (3S,5R,10S,13R,14R,17R)-17-((R)-1,5-dimethyl-hex-4-enyl)-4,4,10,13,14-pentamethyl-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester

Conditions

Conditions	Yield
With pyridine In diethyl ether at 20 - 23℃;	88%

: 913966-90-2
2-bromo-3,4,4-trichloro-3-butenoyl chloride

: 79-63-0
tirucallol

: lanosterolyl 2-bromo-3,4,4-trichlorobut-3-enoate

Conditions

Conditions	Yield
With pyridine In benzene at 20 - 23℃;	87%

: 79-63-0
tirucallol

: 2094-72-6
1-Adamantanecarbonyl chloride

: lanosteryl 1-adamantylmethanoate

Conditions

Conditions	Yield
With pyridine In benzene Heating;	86%

: 79-63-0
tirucallol

: 484067-66-5
3,3,4-trichloro-3-butenoyl chloride

: 3β-lanosteryl 3,4,4-trichloro-3-butenoate

Conditions

Conditions	Yield
With pyridine In diethyl ether at 20 - 23℃;	82%

: 79-63-0
tirucallol

: 1200-22-2
(R)-1,2-dithiolane-3-pentanoic acid

: C38H62O2S2

Conditions

Conditions	Yield
Stage #1: (R)-1,2-dithiolane-3-pentanoic acid With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 5℃; for 0.0833333h; Stage #2: With triethylamine In dichloromethane at 0 - 5℃; for 0.916667h; Stage #3: tirucallol With dmap In dichloromethane at 25 - 30℃; for 5h; Enzymatic reaction;	82%

: 3634-56-8
isopropyldimethylsilyl chloride

: 79-63-0
tirucallol

: C35H62OSi

Conditions

Conditions	Yield
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 10h;	80%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 10h;	80%

: 108-30-5
succinic acid anhydride

: 79-63-0
tirucallol

: 1014978-53-0
4-[(3β)-lanosta-8,24-dien-3-yloxy]-4-oxobutanoic acid

Conditions

Conditions	Yield
With pyridine; dmap at 20℃; for 168h;	79%

: 79-63-0
tirucallol

: 1345457-17-1
(4R)-4-((5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-3-oxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanal

Conditions

Conditions	Yield
Stage #1: tirucallol With oxalyl dichloride; dimethyl sulfoxide In dichloromethane at -60 - -20℃; for 0.0333333h; Swern oxidation; Inert atmosphere; Stage #2: With triethylamine In dichloromethane at -20 - 25℃; Swern oxidation; Inert atmosphere; Stage #3: With ozone In dichloromethane at -50℃; for 0.283333h; Inert atmosphere;	78%

: 2596-47-6, 147677-05-2, 34749-55-8
(E)-3-(4-acetoxy-3-methoxyphenyl)acrylic acid

: 79-63-0
tirucallol

: 3-O-(trans-4-O-acetylferuloyl)-8,24,(5-α)-cholestandien-4,4,14-α-trimethyl-3-β-ol

Conditions

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 1.5h; Inert atmosphere;	77%

: 2459-09-8
4-pyridinecarboxylic acid, methyl ester

: 79-63-0
tirucallol

: Isonicotinic acid (3S,5R,10S,13R,14R,17R)-17-((R)-1,5-dimethyl-hex-4-enyl)-4,4,10,13,14-pentamethyl-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester

Conditions

Conditions	Yield
With n-butyllithium In tetrahydrofuran; hexane for 2h;	73%

: 79-63-0
tirucallol

: 13879-13-5, 54325-09-6, 5539-04-8
lanosta-8,24-dien-3-one

Conditions

Conditions	Yield
With quinolinium chlorochromate(VI) In dichloromethane at 20℃; for 18h;	70%
With chromium trioxide pyridine In dichloromethane for 24h; Ambient temperature;	65%
With pyridinium chlorochromate In dichloromethane at 20℃; for 2h;	45%

: 10258-70-5
β-oxopropyl formate

: 79-63-0
tirucallol

: 115045-75-5
lanosta-8,24-dien-3β-yl formate

Conditions

Conditions	Yield
DBN In tetrahydrofuran at 50 - 70℃; for 3h; Formylation;	70%

: 79-63-0
tirucallol

: 18303-41-8
(3S,5R,10S,13R,14R,17R,20R)-24,25-epoxylanosterol

Conditions

Conditions	Yield
With 3-chloro-benzenecarboperoxoic acid In chloroform at 0℃; for 3h;	70%
With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid In dichloromethane at 20℃; Cooling with ice;

: 79-63-0
tirucallol

: 516-28-9, 566-14-3, 97719-41-0, 6890-88-6
24-methylenelanost-8-en-3-ol

Conditions

Conditions	Yield
With Paracoccidiodes brasiliensis sterol C24-methyltransferase, recombinant; AdoMet Enzymatic reaction;	55%

: 79-63-0
tirucallol

: 24352-48-5
lanosteryl phosphorodichloridate

Conditions

Conditions	Yield
With pyridine; trichlorophosphate In acetone at 0℃; for 4h;	49%
With pyridine; trichlorophosphate In acetone

: 79-63-0
tirucallol

: inoterpene C

Conditions

Conditions	Yield
With oxygen; rose bengal In methanol for 2h; UV-irradiation;	5%

: 79-63-0
tirucallol

: 3α-fluorolanosterol

Conditions

Conditions	Yield
With diethylamino-sulfur trifluoride In n-heptane; dichloromethane at 20℃; for 0.166667h; Inert atmosphere;	1%

Lanosta-8,24-dien-3-ol,(3beta)- Specification

The Lanosta-8,24-dien-3-ol,(3beta)- is an organic compound with the formula C₃₀H₅₀O. The IUPAC name of this chemical is (3S,5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-[(2R)-6-methylhept-5-en-2-yl]-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol. With the CAS registry number 79-63-0, it is also named as (3β)-Lanosta-8,24-dien-3-ol. The product's categories are Miscellaneous Natural Products; Organics; Biochemistry; Hydroxysteroids; Steroids. Besides, it should be stored in a closed and cool place. It is used for atherosclerosis research.

Physical properties about Lanosta-8,24-dien-3-ol,(3beta)- are: (1)ACD/LogP: 10.52; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): 10.521; (4)ACD/LogD (pH 7.4): 10.521; (5)ACD/BCF (pH 5.5): 1000000; (6)ACD/BCF (pH 7.4): 1000000; (7)ACD/KOC (pH 5.5): 10000000; (8)ACD/KOC (pH 7.4): 10000000; (9)#H bond acceptors: 1; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 5; (12)Polar Surface Area: 20.23 Å²; (13)Index of Refraction: 1.53; (14)Molar Refractivity: 133.401 cm³; (15)Molar Volume: 431.845 cm³; (16)Polarizability: 52.884×10^-24cm³; (17)Surface Tension: 37.965 dyne/cm; (18)Density: 0.988 g/cm³; (19)Flash Point: 221.143 °C; (20)Enthalpy of Vaporization: 88.348 kJ/mol; (21)Boiling Point: 498.855 °C at 760 mmHg.

Uses of Lanosta-8,24-dien-3-ol,(3beta)-: it can be used to produce (5a)-euph-8-en-3b-ol at ambient temperature. It will need reagent H₂, catalyst Pd/C (10 percent) and solvent ethanol with reaction time of 4 hours. The yield is about 85%.

You can still convert the following datas into molecular structure:
(1)SMILES: C[C@H](CCC=C(C)C)[C@H]1CC[C@@]2([C@@]1(CCC3=C2CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)C
(2)InChI:InChI=1/C30H50O/c1-20(2)10-9-11-21(3)22-14-18-30(8)24-12-13-25-27(4,5)26(31)16-17-28(25,6)23(24)15-19-29(22,30)7/h10,21-22,25-26,31H,9,11-19H2,1-8H3/t21-,22-,25+,26+,28-,29-,30+/m1/s1
(3)InChIKey: CAHGCLMLTWQZNJ-BQNIITSRBP
(4)Std. InChI: InChI=1S/C30H50O/c1-20(2)10-9-11-21(3)22-14-18-30(8)24-12-13-25-27(4,5)26(31)16-17-28(25,6)23(24)15-19-29(22,30)7/h10,21-22,25-26,31H,9,11-19H2,1-8H3/t21-,22-,25+,26+,28-,29-,30+/m1/s1
(5)Std. InChIKey: CAHGCLMLTWQZNJ-BQNIITSRSA-N

Product Name

LANOSTEROL

Synthetic route

Lanosta-8,24-dien-3-ol,(3beta)- Specification

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