Product Name

  • Name

    Lincomycin hydrochloride monohydrate

  • EINECS 212-726-7
  • CAS No. 7179-49-9
  • Density
  • Solubility
  • Melting Point 156-158°
  • Formula C18H34N2O6S.HCl.H2O
  • Boiling Point 646.8 °C at 760 mmHg
  • Molecular Weight 461.01
  • Flash Point 345 °C
  • Transport Information
  • Appearance White powder
  • Safety 26
  • Risk Codes 36/37/38
  • Molecular Structure Molecular Structure of 7179-49-9 (Lincomycin hydrochloride monohydrate)
  • Hazard Symbols IrritantXi
  • Synonyms D-erythro-D-galacto-Octopyranoside,methyl 6,8-dideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-,monohydrochloride, monohydrate, trans-a- (8CI);D-erythro-a-D-galacto-Octopyranoside, methyl 6,8-dideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-,monohydrochloride, monohydrate, (2S-trans)-;Methyl 6,8-dideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-D-erythro-alpha-D-galacto-octopyranoside monohydrochloride monohydrate;Lincomycin, hydrochloride hydrate;Lincomycin HCL;
  • PSA 157.02000
  • LogP 0.20950

Lincomycin hydrochloride monohydrate Chemical Properties

IUPAC Name: (2S,4R)-N-[(1R,2R)-2-Hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide hydrate hydrochloride
Synonyms of Lincomycin, hydrochloride hydrate (CAS NO.7179-49-9): Lincomycin hydrochloride [USAN:JAN] ; CCRIS 9080 ; Lincocin ; Lincomix ; Lincomycin HCl ; Lincomycin hydrochloride ; Lincomycin hydrochloride monohydrate ; Lincomycin soluble ; Lincomycin, hydrochloride hydrate ; Methyl 6,8-dideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-D-erythro-alpha-D-galacto-octopyranoside monohydrochloride monohydrate ;  NSC 70731 ; UNII-M6T05Z2B68 ; D-erythro-D-galacto-Octapyranoside, methyl 6,8-dideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-, monohydrochloride, monohydrate, trans-alpha- ; D-erythro-alpha-D-galacto-Octopyranoside, methyl 6,8-dideoxy-6-(((1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-, monohydrochloride, monohydrate, (2S-trans)-
CAS NO: 7179-49-9
Classification Code: Antibacterial ; Drug / Therapeutic Agent ; Human Data
Molecular Formula of Lincomycin, hydrochloride hydrate (CAS NO.7179-49-9): C18H37ClN2O7S
Molecular Weight: 461.0136
Molecular Structure:

Appearance:White powder
storage temp:2-8°C
Merck:5500 
Polar Surface Area: 95 Å2
Flash Point: 345 °C
Enthalpy of Vaporization: 109.25 kJ/mol
Boiling Point of Lincomycin, hydrochloride hydrate (CAS NO.7179-49-9): 646.8 °C at 760 mmHg
Vapour Pressure: 1.85E-19 mmHg at 25°C

Lincomycin hydrochloride monohydrate Uses

 Lincomycin, hydrochloride hydrate (CAS NO.7179-49-9) has  a strong antibacterial effect ,which is similar to the Gram-positive bacteria.

Lincomycin hydrochloride monohydrate Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1gm/kg (1000mg/kg)   "Compounds Available for Fundamental Research, Volume II-6, Antibiotics, A Program of Upjohn Company Research Laboratory." Vol. 2(6), Pg. -, 1971.
mouse LD50 intravenous 214mg/kg (214mg/kg)   Drugs in Japan Vol. 6, Pg. 891, 1982.
rat LD50 intravenous 342mg/kg (342mg/kg)   Drugs in Japan Vol. 6, Pg. 891, 1982.
rat LD50 oral > 4gm/kg (4000mg/kg)   "Compounds Available for Fundamental Research, Volume II-6, Antibiotics, A Program of Upjohn Company Research Laboratory." Vol. 2(6), Pg. -, 1971.
rat LD50 subcutaneous 9778mg/kg (9778mg/kg)   "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 65, 1969.
women TDLo oral 192mg/kg/8D-I (192mg/kg) BLOOD: NORMOCYTIC ANEMIA Postgraduate Medical Journal. Vol. 59, Pg. 796, 1983.

Lincomycin hydrochloride monohydrate Safety Profile

Hazard Codes: IrritantXi
Risk Statements: 36/37/38 
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 26 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
RTECS: RH6315500
Poison by intravenous route. Moderately toxic by intraperitoneal route. Used as an antibacterial agent. When heated to decomposition it emits toxic fumes of SOx, NOx, and HCl.

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