Methyl 3-methyl-2-butenoate supplier

Name
Methyl 3-methyl-2-butenoate
EINECS 213-107-4
CAS No. 924-50-5
Article Data68
CAS DataBase
Density 0.916 g/cm³
Solubility Soluble in chloroform. Insoluble in water,
Melting Point -41°C
Formula C₆H₁₀O₂
Boiling Point 136.5 °C at 760 mmHg
Molecular Weight 114.144
Flash Point 32.1 °C
Transport Information UN 3272 3/PG 3
Appearance colorless transparent liquid
Safety 16-29-33
Risk Codes 10
Molecular Structure
Hazard Symbols Xi
Synonyms Methyl 3,3-dimethylacrylate
PSA 26.30000
LogP 1.12560

Synthetic route

: 67-56-1
methanol

: 541-47-9
3-Methylbutenoic acid

: 924-50-5
Methyl 3,3-dimethylacrylate

Conditions

Conditions	Yield
With [1-(3-sulfonic acid)]propyl-3-methylimidazolium hydrogen sulfate for 3h; Reflux; Green chemistry;	97.8%
With sulfuric acid	95%
With sulfuric acid for 16h; Heating;	92%

: 105245-42-9
tert-butyl(1-methoxyvinyl)dimethylsilane

: 67-64-1
acetone

: 924-50-5
Methyl 3,3-dimethylacrylate

Conditions

Conditions	Yield
Stage #1: tert-butyl(1-methoxyvinyl)dimethylsilane; acetone With C40H61Al3O3 In acetonitrile at 0 - 5℃; for 72h; Mukaiyama Aldol Addition; Stage #2: With hydrogenchloride In water; acetonitrile at 20℃; for 3h; Mukaiyama Aldol Addition;	90%

: 67-56-1
methanol

: 135765-56-9
C9H18ClNO3

A: 924-50-5
Methyl 3,3-dimethylacrylate

B: 82004-48-6
β-(N-methoxy-N-isopropoxyamino)-isovaleric acid methyl ester

Conditions

Conditions	Yield
With triethylamine 1.) -20 deg C, 6 h, 2.) 20 deg C, 1 h;	A 14% B 86%

...Expand

: 27652-13-7, 50465-52-6, 19041-17-9
(E)-4-bromo-3-methyl-2-butenoic acid methyl ester

A: 924-50-5
Methyl 3,3-dimethylacrylate

B: 91664-11-8
(E)-5-Isopropenyl-3-methyl-hex-2-enedioic acid dimethyl ester

Conditions

Conditions	Yield
With zinc In dimethyl sulfoxide for 4h;	A 10% B 68%

: 27652-13-7
(Z)-methyl-β-bromomethyl-β-methylacrylate

A: 924-50-5
Methyl 3,3-dimethylacrylate

B: 91664-12-9
(Z)-5-Isopropenyl-3-methyl-hex-2-enedioic acid dimethyl ester

Conditions

Conditions	Yield
With zinc In dimethyl sulfoxide for 4h;	A 10% B 67%

: 70569-70-9
β-(N-chloro-N-methoxyamino)-isovaleric acid methyl ester

: 115-11-7
isobutene

A: 924-50-5
Methyl 3,3-dimethylacrylate

B: 135765-48-9
β-isovaleric acid methyl ester

Conditions

Conditions	Yield
With sulfur dioxide 1.) 7 deg C, 24 h, 2.) 20 deg C, 2 h;	A 13% B 67%

...Expand

: 76430-13-2
2,2,3,3-tetracyano-4,4-dimethylcyclopentanone dimethyl acetal

A: 924-50-5
Methyl 3,3-dimethylacrylate

B: 76430-21-2
methyl 3,3-dimethyl-4,5,5-tricyano-4-pentenoate

C: 76430-18-7
methyl 3,3-dimethyl-4,4,5,5-tetracyanopentanoate

Conditions

Conditions	Yield
With water In acetonitrile at 80℃; for 12h;	A n/a B n/a C 63%

...Expand

: 101146-22-9
(2-Trifluoromethanesulfonyl-pentane-2-sulfonyl)-acetic acid methyl ester

: 924-50-5
Methyl 3,3-dimethylacrylate

Conditions

Conditions	Yield
With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate In dichloromethane; water	62%

: 70569-71-0
β-(N,N-dimethoxyamino)-isovaleric acid methyl ester

A: 924-50-5
Methyl 3,3-dimethylacrylate

B: 80552-91-6
3-(2-Methoxycarbonyl-1,1-dimethyl-ethyl-NNO-azoxy)-3-methyl-butyric acid methyl ester

Conditions

Conditions	Yield
With triethylamine hydrochloride In chloroform for 126h; Product distribution; Heating; various acyclic N,N-dialkoxyamines;	A 15% B 51.9%

: 63282-42-8
methyl 2-diazo-3-methylbutanoate

: 924-50-5
Methyl 3,3-dimethylacrylate

Conditions

Conditions	Yield
at 400℃; under 0.001 - 0.1 Torr;	47%

: 67-56-1
methanol

: 74966-50-0
4,4-dimethyl-2-(2-propylidene)-3-thietanone

A: 924-50-5
Methyl 3,3-dimethylacrylate

B: 74966-53-3
4-Isopropylidene-5-methoxy-2,2-dimethyl-[1,3]oxathiolane

Conditions

Conditions	Yield
In methanol for 3h; Irradiation;	A 28% B 22%

...Expand

: 74966-46-4
3-diazo-2,2,5,5-tetramethylthiolan-4-one

A: 924-50-5
Methyl 3,3-dimethylacrylate

B: 74966-52-2
2,2,4,4-Tetramethyl-thietane-3-carboxylic acid methyl ester

C: 74966-53-3
4-Isopropylidene-5-methoxy-2,2-dimethyl-[1,3]oxathiolane

Conditions

Conditions	Yield
In methanol Irradiation;	A 19% B 28% C 14%

...Expand

: 74966-50-0
4,4-dimethyl-2-(2-propylidene)-3-thietanone

A: 924-50-5
Methyl 3,3-dimethylacrylate

B: 74966-53-3
4-Isopropylidene-5-methoxy-2,2-dimethyl-[1,3]oxathiolane

Conditions

Conditions	Yield
In methanol Irradiation;	A 28% B 22%

: 67-56-1
methanol

A: 924-50-5
Methyl 3,3-dimethylacrylate

B: 74966-52-2
2,2,4,4-Tetramethyl-thietane-3-carboxylic acid methyl ester

C: 74966-53-3
4-Isopropylidene-5-methoxy-2,2-dimethyl-[1,3]oxathiolane

Conditions

Conditions	Yield
Irradiation;	A 19% B 27.8% C 14%

...Expand

: 70569-70-9
β-(N-chloro-N-methoxyamino)-isovaleric acid methyl ester

: 75-05-8
acetonitrile

A: 924-50-5
Methyl 3,3-dimethylacrylate

B: 43135-04-2
methyl β-(Nacetylamino)isovalerate

Conditions

Conditions	Yield
With silver fluoride at -78℃; for 15h;	A n/a B 27.8%

...Expand

: 69367-52-8, 70332-52-4, 114528-93-7, 26330-51-8
methyl 2-bromo-3-methylbutanoic ester

A: 616-45-5
2-pyrrolidinon

B: 924-50-5
Methyl 3,3-dimethylacrylate

C: 2857-97-8
trimethylsilyl bromide

Conditions

Conditions	Yield
With N-trimethylsilyl-pyrrolidin-2-one at 165 - 195℃; for 3h; Yields of byproduct given;	A n/a B 27% C n/a

...Expand

: 27830-36-0
methyl (2,2-dimethyl-3-oxocyclobutyl)acetate

A: 924-50-5
Methyl 3,3-dimethylacrylate

B: 38306-10-4
methyl 2-(2,2-dimethyl-5-oxotetrahydrofuran-3-yl)acetate

C: 121757-31-1
Methyl 2,2-dimethyl-4,5-dihydro-3-furanacetate

D: 121757-32-2
Methyl 2,2-dimethyl-5-(2,2-dimethyltetrahydro-3-(methoxycarbonyl)furan-5-ylidene)tetrahydro-3-furanacetate

Conditions

Conditions	Yield
With 4 A molecular sieve In dichloromethane for 72h; Irradiation; Further byproducts given;	A 16% B n/a C 12% D 22%

...Expand

: 67-56-1
methanol

: 75-25-2
Bromoform

: 67-64-1
acetone

: 924-50-5
Methyl 3,3-dimethylacrylate

Conditions

Conditions	Yield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In benzonitrile; acetonitrile at 20℃; for 5h;	22%

...Expand

: 3,3-dimethyl-4-oxo-oxetane-2-carboxylic acid methyl ester

A: 924-50-5
Methyl 3,3-dimethylacrylate

B: 15719-64-9, 15719-76-3, 97762-63-5
methylammonium carbonate

Conditions

Conditions	Yield
bei der Destillation im Vakuum ueber eine rotgluehende Platinspirale;

: 60-29-7
diethyl ether

: 85526-21-2
3,4-Dibromo-3-methyl-butan-2-one

: 124-41-4
sodium methylate

A: 924-50-5
Methyl 3,3-dimethylacrylate

B: 56830-25-2
β-methoxy-isovaleric acid methyl ester

...Expand

: 25859-52-3
methyl 3-methyl-3-butenoate

: 124-41-4
sodium methylate

A: 924-50-5
Methyl 3,3-dimethylacrylate

B: 56830-25-2
β-methoxy-isovaleric acid methyl ester

Conditions

Conditions	Yield
With diethyl ether

...Expand

: 85526-21-2
3,4-Dibromo-3-methyl-butan-2-one

: 124-41-4
sodium methylate

A: 924-50-5
Methyl 3,3-dimethylacrylate

B: 56830-25-2
β-methoxy-isovaleric acid methyl ester

Conditions

Conditions	Yield
With diethyl ether anfangs unter Kuehlung;
With diethyl ether

...Expand

: 69367-52-8, 70332-52-4, 114528-93-7, 26330-51-8
methyl 2-bromo-3-methylbutanoic ester

: 924-50-5
Methyl 3,3-dimethylacrylate

Conditions

Conditions	Yield
With N,N-diethylaniline

: 67-56-1
methanol

: 35044-52-1
ethyl 2-acetyl-3-methylbut-2-enoate

: 74-88-4
methyl iodide

: 924-50-5
Methyl 3,3-dimethylacrylate

Conditions

Conditions	Yield
With sodium methylate

...Expand

: 67-56-1
methanol

: 63364-70-5
isopropylideneketene

: 924-50-5
Methyl 3,3-dimethylacrylate

Conditions

Conditions	Yield
at -196.1℃;

: 67-56-1
methanol

: 27830-36-0
methyl (2,2-dimethyl-3-oxocyclobutyl)acetate

A: 924-50-5
Methyl 3,3-dimethylacrylate

B: 20602-89-5
(2,2-Dimethyl-cyclopropyl)-essigsaeuremethylester

: 113371-55-4, 113371-56-5
Methyl (3R*,5S*)-5-methoxy-2,2-dimethyltetrahydro-3-furanacetate

: 113371-55-4, 113371-56-5
Methyl (3R*,5R*)-5-methoxy-2,2-dimethyltetrahydro-3-furanacetate

Conditions

Conditions	Yield
for 16h; Irradiation; Yield given. Yields of byproduct given;

...Expand

: 31525-65-2
3-methyl-but-2-enal dimethyl acetal

A: 924-50-5
Methyl 3,3-dimethylacrylate

B: 107-86-8
3,3-dimethyl acrylaldehyde

C: 87128-47-0
3-Dimethoxymethyl-2,2-dimethyl-oxirane

Conditions

Conditions	Yield
With potassium fluoride; sodium fluoride; 3-chloro-benzenecarboperoxoic acid In dichloromethane 1.) 15 h, RT; 2.) 1 h, RT;

...Expand

: 100342-98-1
β,β-Di(3>methyl)acrylsaeure-methylester

: 924-50-5
Methyl 3,3-dimethylacrylate

Conditions

Conditions	Yield
With potassium hydroxide In methanol

: 144864-97-1
methyl tert-butyl(pivaloyl)acetate

A: 924-50-5
Methyl 3,3-dimethylacrylate

B: 10250-48-3
methyl 3,3-dimethylbutyrate

Conditions

Conditions	Yield
at 900℃; under 8E-05 Torr; Product distribution;

: 144864-97-1
methyl tert-butyl(pivaloyl)acetate

A: 924-50-5
Methyl 3,3-dimethylacrylate

B: 10250-48-3
methyl 3,3-dimethylbutyrate

C: 55107-14-7
Methyl 4,4-dimethyl-3-oxopentanoate

D: 115-11-7
isobutene

E: 108-59-8
malonic acid dimethyl ester

Conditions

Conditions	Yield
at 600℃; under 8E-05 Torr; Product distribution; other temperatures;

...Expand

: 924-50-5
Methyl 3,3-dimethylacrylate

: 39691-62-8
nonylmagnesium bromide

: methyl 3,3-dimethyldodecanoate

Conditions

Conditions	Yield
With copper(l) iodide; chloro-trimethyl-silane In tetrahydrofuran; diethyl ether at -15 - 20℃;	100%
With chloro-trimethyl-silane; copper(l) iodide In tetrahydrofuran at -15 - 20℃;
With copper(l) iodide; chloro-trimethyl-silane In tetrahydrofuran at -15 - 20℃;

: 924-50-5
Methyl 3,3-dimethylacrylate

: 42953-82-2
5,5-dimethylpyrazolidin-3-one

Conditions

Conditions	Yield
With hydrazine hydrate In ethanol at 20℃; for 5h; Reflux;	99%

: 924-50-5
Methyl 3,3-dimethylacrylate

: 2935-90-2
Methyl 3-mercaptopropionate

: 3-(2-methoxycarbonyl-ethylsulfanyl)-3-methylbutyric acid methyl ester

Conditions

Conditions	Yield
Stage #1: Methyl 3,3-dimethylacrylate With piperidine; N-benzyl-trimethylammonium hydroxide In methanol at 0℃; Inert atmosphere; Stage #2: Methyl 3-mercaptopropionate at 60℃; for 24h; Inert atmosphere;	97.23%
With piperidine; N-benzyl-trimethylammonium hydroxide In methanol at 0 - 60℃; for 24h; Inert atmosphere;	97%
With piperidine; N-benzyl-trimethylammonium hydroxide In methanol at 60℃; for 24h; Michael addition;	75%

: 924-50-5
Methyl 3,3-dimethylacrylate

: 108-68-9
3,5-Dimethylphenol

: 40662-14-4
4,4,5,7-tetramethyl-3,4-dihydrocoumarin

Conditions

Conditions	Yield
With methanesulfonic acid at 70℃; for 6h;	96%
With sulfuric acid Michael Addition; Reflux;	93%
With methanesulfonic acid at 20 - 70℃; for 17h;	92%

: 924-50-5
Methyl 3,3-dimethylacrylate

: 32064-67-8
tert-butylhydrazine

: 3-(N'-tert-Butyl-hydrazino)-3-methyl-butyric acid methyl ester

Conditions

Conditions	Yield
In Dimethyl ether for 168h;	96%

: 67-56-1
methanol

: 924-50-5
Methyl 3,3-dimethylacrylate

: methyl 2-iodo-3-methoxy-3-methylbutanoate

Conditions

Conditions	Yield
With ammonium cerium (IV) nitrate; iodine at 50℃; for 15h;	96%

: 924-50-5
Methyl 3,3-dimethylacrylate

: 108-68-9
3,5-Dimethylphenol

: 3,3,5,7-tetramethylchroman-2-one

Conditions

Conditions	Yield
With methanesulfonic acid at 70℃;	96%

: 924-50-5
Methyl 3,3-dimethylacrylate

: 17049-50-2
n-decyl magnesium bromide

: methyl 3,3-dimethyltridecanoate

Conditions

Conditions	Yield
With copper(l) iodide; chloro-trimethyl-silane In tetrahydrofuran; 2-methyltetrahydrofuran at -15 - 20℃; Inert atmosphere;	96%

: 924-50-5
Methyl 3,3-dimethylacrylate

: 36727-29-4
isononanoyl chloride

: 3,7,9,9-tetramethyl-2-decen-5-onic acid methyl ester

Conditions

Conditions	Yield
With aluminum (III) chloride; tin(IV) chloride at 40℃; for 5h; Time; Cooling with ice; Reflux;	95.4%
Stage #1: isononanoyl chloride With aluminum (III) chloride In dichloromethane at 30℃; for 0.666667h; Stage #2: Methyl 3,3-dimethylacrylate In dichloromethane at 38℃; for 1h; Temperature;
Stage #1: isononanoyl chloride With aluminum (III) chloride In dichloromethane for 5h; Stage #2: Methyl 3,3-dimethylacrylate In dichloromethane at 40℃; for 10h; Time;
Stage #1: isononanoyl chloride With anhydrous aluminum chloride, anhydrous lanthanum chloride, anhydrous lithium perchlorate on silica gel catalyst In dichloromethane at 0℃; for 1h; Stage #2: Methyl 3,3-dimethylacrylate In dichloromethane at 25 - 40℃; for 11h; Temperature;

: 924-50-5
Methyl 3,3-dimethylacrylate

: 58461-27-1
(+/-)-lavandulol

A: 23960-07-8
2-isopropenyl-5-methyl-4-hexen-1-yl 3-methyl-2-butenoate

B: 2-isopropenyl-5-methyl-4-hexen-1-yl 3-methyl-3-butenoate

Conditions

Conditions	Yield
With titanium(IV) isopropylate In toluene at 100℃; Temperature; Reagent/catalyst;	A 94.9% B n/a

...Expand

: 924-50-5
Methyl 3,3-dimethylacrylate

: 63881-44-7
2,3-dibromo-3-metyl-butenoate

Conditions

Conditions	Yield
With bromine In dichloromethane at 0℃; for 0.25h; Inert atmosphere; Schlenk technique;	94%
With bromine In dichloromethane at 0℃; for 10h;	73%
With tetrachloromethane; bromine
With bromine
With bromine In neat (no solvent) for 48h; from -50 deg C to -70 deg C;

: 924-50-5
Methyl 3,3-dimethylacrylate

: 105-67-9
2,4-Xylenol

: 249629-60-5
4,4,6,8-tetramethyldihydrocoumarin

Conditions

Conditions	Yield
With methanesulfonic acid at 70℃; Condensation; cyclization;	93%

: 924-50-5
Methyl 3,3-dimethylacrylate

: 106-95-6
allyl bromide

: 99799-91-4
2-(prop-1-en-2-yl)pent-4-en-1-ol

Conditions

Conditions	Yield
Stage #1: Methyl 3,3-dimethylacrylate With n-butyllithium; diisopropylamine In tetrahydrofuran at -78 - 0℃; for 1.83333h; Inert atmosphere; Cooling with acetone-dry ice; Stage #2: allyl bromide In tetrahydrofuran at -78 - 0℃; for 15h; Inert atmosphere; Cooling with acetone-dry ice; Stage #3: With lithium aluminium tetrahydride In tetrahydrofuran for 3h; Inert atmosphere;	93%
Stage #1: Methyl 3,3-dimethylacrylate; allyl bromide With lithium diisopropyl amide Inert atmosphere; Stage #2: With lithium aluminium tetrahydride Inert atmosphere;	93%

: 924-50-5
Methyl 3,3-dimethylacrylate

: methyl 3-hydroxy-3-methyl-2-iodobutanoate

Conditions

Conditions	Yield
With ammonium cerium (IV) nitrate; water; iodine In acetonitrile at 50℃; for 9h; Reagent/catalyst;	93%

: 924-50-5
Methyl 3,3-dimethylacrylate

: 556-24-1
methyl 3-methylbutanoate

Conditions

Conditions	Yield
With zinc copper In methanol for 24h; Heating;	88%
With magnesium In methanol at 10℃; for 2.5h;	78%
With platinum(IV) oxide Hydrogenation;

: 924-50-5
Methyl 3,3-dimethylacrylate

: 917-54-4
methyllithium

: 56763-70-3
2,4-dimethyl-3-penten-2-ol

Conditions

Conditions	Yield
In diethyl ether at 0℃; for 1h;	88%

: 924-50-5
Methyl 3,3-dimethylacrylate

: 700-13-0
Trimethylhydroquinone

: 40662-76-8
6-hydroxy-4,4,5,7,8-pentamethyl-3,4-dihydrocoumarin

Conditions

Conditions	Yield
With methanesulfonic acid	87%
With methanesulfonic acid at 70℃; for 3h;	81.2%
With methanesulfonic acid at 70℃; for 2h;	80%

: 924-50-5
Methyl 3,3-dimethylacrylate

: 18162-48-6
tert-butyldimethylsilyl chloride

: tert-butyl-(1-methoxy-3-methyl-buta-1,3-dienyloxy)-dimethyl-silane

Conditions

Conditions	Yield
With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; n-butyllithium; diisopropylamine In tetrahydrofuran at -78 - 20℃; for 1.5h;	87%

: 924-50-5
Methyl 3,3-dimethylacrylate

: 29637-56-7
methyl 3-amino-3-methyl-butanoate

Conditions

Conditions	Yield
With ammonia In methanol at 120℃; for 4h; Inert atmosphere; Microwave irradiation;	87%

: 924-50-5
Methyl 3,3-dimethylacrylate

: 59807-81-7
<(phenylsuilfonyl)methylene>dilithium

: 107006-44-0
1-benzenesulfonyl-4-methylpent-3-en-2-one

Conditions

Conditions	Yield
	86%

: 924-50-5
Methyl 3,3-dimethylacrylate

: 563-47-3
3-Chloro-2-methylpropene

: 2,6-dimethyl-4-(2'-methyl-2'-propenyl)-1,5-heptadien-4-ol

Conditions

Conditions	Yield
With magnesium In tetrahydrofuran Heating;	86%

: 924-50-5
Methyl 3,3-dimethylacrylate

: [1,1-(2)H2]-3-methyl-2-buten-1-ol

Conditions

Conditions	Yield
With lithium aluminium deuteride at 20℃; for 2h;	86%

: 924-50-5
Methyl 3,3-dimethylacrylate

: 6158-92-5
[1,1-2H2]-3-methyl-2-butenol

Conditions

Conditions	Yield
With lithium aluminium deuteride	86%
With lithium aluminium deuteride In diethyl ether at 0℃; for 1h; Inert atmosphere; Reflux;	76%

: 924-50-5
Methyl 3,3-dimethylacrylate

: (R)-1-methyl-4-(1-(phenylsulfonyl)propan-2-yl)benzene

: (6R)-2-methyl-5-(phenylsulfonyl)-6-p-tolylhept-2-en-4-one

Conditions

Yield

Stage #1: (R)-1-methyl-4-(1-(phenylsulfonyl)propan-2-yl)benzene With n-butyllithium In tetrahydrofuran at -78 - -50℃; Inert atmosphere; Glovebox; Schlenk technique;
Stage #2: With magnesium bromide ethyl etherate In tetrahydrofuran at -78 - 20℃; for 0h; Inert atmosphere; Glovebox; Schlenk technique;
Stage #3: Methyl 3,3-dimethylacrylate In tetrahydrofuran at -78 - 20℃; Inert atmosphere; Glovebox; Schlenk technique;

85%

Stage #1: (R)-1-methyl-4-(1-(phenylsulfonyl)propan-2-yl)benzene With n-butyllithium In tetrahydrofuran; hexane at -50℃; Inert atmosphere;
Stage #2: With magnesium bromide ethyl etherate In tetrahydrofuran; diethyl ether; hexane at -78 - 0℃; for 0.166667h; Inert atmosphere;
Stage #3: Methyl 3,3-dimethylacrylate In tetrahydrofuran; diethyl ether; hexane at -78 - 20℃; Inert atmosphere; enantioselective reaction;

77%

: 924-50-5
Methyl 3,3-dimethylacrylate

: 73945-79-6
7-methyl-3-methylene-7-octen-1-ol

: 7-methyl-3-methylene-7-octenyl senecioate

Conditions

Conditions	Yield
With titanium(IV) isopropylate Inert atmosphere; Heating;	84.7%

: 924-50-5
Methyl 3,3-dimethylacrylate

: (4-(tert-butyldimethylsilyloxy)butyl)magnesium chloride

: C15H30O2Si

Conditions

Conditions	Yield
Stage #1: (4-(tert-butyldimethylsilyloxy)butyl)magnesium chloride With zirconocene dichloride In tetrahydrofuran; toluene at 0℃; for 3h; Stage #2: Methyl 3,3-dimethylacrylate In tetrahydrofuran; toluene at 0 - 20℃;	84%

: 110-85-0
piperazine

: 924-50-5
Methyl 3,3-dimethylacrylate

: 1260115-90-9
dimethyl 3,3'-(piperazine-1,4-diyl)bis-(3-methylbutanoate)

Conditions

Conditions	Yield
In tetrahydrofuran; methanol at 20℃; for 24h; Aza-Michael addition; hyperbaric;	84%

Methyl 3-methyl-2-butenoate Chemical Properties

Molecular Structure of Methyl 3-methyl-2-butenoate (CAS NO.924-50-5):

IUPAC Name: methyl 3-methylbut-2-enoate
Empirical Formula: _C6H₁₀O₂
Molecular Weight: 114.1424
H bond acceptors: 2
H bond donors: 0
Freely Rotating Bonds: 2
Polar Surface Area: 26.3Å²
Index of Refraction: 1.42
Molar Refractivity: 31.52 cm³
Molar Volume: 124.4 cm³
Surface Tension: 25.2 dyne/cm
Density: 0.916 g/cm³
Flash Point: 32.1 °C
Enthalpy of Vaporization: 37.39 kJ/mol
Boiling Point: 136.5 °C at 760 mmHg
Vapour Pressure: 7.36 mmHg at 25°C
Melting point: -41°C
InChI
InChI=1/C6H10O2/c1-5(2)4-6(7)8-3/h4H,1-3H3
Smiles
C(\C=C(\C)C)(OC)=O
EINECS: 213-107-4
Product Categories: (intermediate of Gancyclovir)

Methyl 3-methyl-2-butenoate Safety Profile

Hazard Codes: Irritant Xi
Risk Statements: 10
R10:Flammable.
Safety Statements: 16-29-33
S16:Keep away from sources of ignition.
S29:Do not empty into drains.
S33:Take precautionary measures against static discharges.
RIDADR: UN 3272 3/PG 3
WGK Germany: 1
F: 8
Hazard Note: Irritant
HazardClass: 3
PackingGroup: III

Methyl 3-methyl-2-butenoate Specification

Methyl 3-methyl-2-butenoate , with CAS number of 924-50-5, can be called Senecioic acid, methyl ester (6CI) ; 3-Methyl-2-butenoic acid methyl ester ; 3-Methylcrotonic acid methyl ester ; Methyl 3,3-dimethacrylate ; Methyl 3,3-dimethylacrylate ; Methyl b,b-dimethylacrylate .

Product Name

Methyl 3-methyl-2-butenoate

Synthetic route

Methyl 3-methyl-2-butenoate Chemical Properties

Methyl 3-methyl-2-butenoate Safety Profile

Methyl 3-methyl-2-butenoate Specification

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